Mesh term Integrin alpha2beta1
Browse to parent terms:Platelet Membrane Glycoproteins
Receptors, Collagen
Receptors, Fibronectin
Receptors, Laminin
Receptors, Very Late Antigen
Description
An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.Search for this term in our Faculty Database
View this term at the NCBI website
