Mesh term Congenital Hyperinsulinism
Browse to parent terms:Hyperinsulinism
Hypoglycemia
Infant, Newborn, Diseases
Pancreatic Diseases
Description
A familial, nontransient HYPOGLYCEMIA with defects in negative feedback of GLUCOSE-regulated INSULIN release. Clinical phenotypes include HYPOGLYCEMIA; HYPERINSULINEMIA; SEIZURES; COMA; and often large BIRTH WEIGHT. Several sub-types exist with the most common, type 1, associated with mutations on an ATP-BINDING CASSETTE TRANSPORTERS (subfamily C, member 8).Browse to child terms:
Nesidioblastosis
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