Mesh term Receptors, Tumor Necrosis Factor, Type I
Browse to parent terms:Receptors, Death Domain
Receptors, Tumor Necrosis Factor
Description
A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.Search for this term in our Faculty Database
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