Medical College of Wisconsin
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Mesh term Crk-Associated Substrate Protein

Browse to parent terms:
Adaptor Proteins, Signal Transducing
Phosphoproteins

Description

Crk-associated substrate was originally identified as a highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It is a signal transducing adaptor protein that undergoes tyrosine PHOSPHORYLATION in signaling pathways that regulate CELL MIGRATION and CELL PROLIFERATION.



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