Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Mesh term Cyclin-Dependent Kinase Inhibitor p27

Browse to parent terms:
Cyclin-Dependent Kinase Inhibitor Proteins

Description

A cyclin-dependent kinase inhibitor that coordinates the activation of CYCLIN and CYCLIN-DEPENDENT KINASES during the CELL CYCLE. It interacts with active CYCLIN D complexed to CYCLIN-DEPENDENT KINASE 4 in proliferating cells, while in arrested cells it binds and inhibits CYCLIN E complexed to CYCLIN-DEPENDENT KINASE 2.



Search for this term in our Faculty Database



View this term at the NCBI website