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Mesh term Interferon-Stimulated Gene Factor 3

Browse to parent terms:
Adaptor Proteins, Signal Transducing
DNA-Binding Proteins
Transcription Factors


A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.

Browse to child terms:
Interferon-Stimulated Gene Factor 3, alpha Subunit
Interferon-Stimulated Gene Factor 3, gamma Subunit

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