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Mesh term Proto-Oncogene Proteins c-bcl-6

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DNA-Binding Proteins
Proto-Oncogene Proteins
Transcription Factors


A DNA-binding protein that contains an N-terminal BTB (POZ) DOMAIN and C-terminal CYS2-HIS2 ZINC FINGERS. It represses GENETIC TRANSCRIPTION of target genes by recruiting HISTONE DEACETYLASES. Aberrant Blc-6 expression is associated with certain types of human B-CELL LYMPHOMA.

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