Medical College of Wisconsin
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Mesh term Receptors, Tumor Necrosis Factor, Member 25

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Receptors, Death Domain
Receptors, Tumor Necrosis Factor

Description

A tumor necrosis factor receptor subtype with specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15. It is found in tissues containing LYMPHOCYTES and may play a role in regulating lymphocyte homeostasis and APOPTOSIS. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.



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