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Mesh term Receptor Activator of Nuclear Factor-kappa B

Browse to parent terms:
Receptors, Tumor Necrosis Factor

Description

A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.



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