Mesh term Caspases, Initiator
Browse to parent terms:Caspases
Description
A subtype of caspases that contain long pro-domain regions that regulate the activation of the enzyme. The pro-domain regions contain protein-protein interaction motifs that can interact with specific signaling adaptor proteins such as DEATH DOMAIN RECEPTORS; DED SIGNALING ADAPTOR PROTEINS; and CARD SIGNALING ADAPTOR PROTEINS. Once activated, the initiator caspases can activate other caspases such as the EFFECTOR CASPASES.Browse to child terms:
Caspase 1
Caspase 10
Caspase 12
Caspase 2
Caspase 8
Caspase 9
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