Mesh term RecQ Helicases
Browse to parent terms:DNA Helicases
Description
A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.Browse to child terms:
Werner Syndrome Helicase
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