Mesh term Janus Kinases
Browse to parent terms:Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Description
A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains.Browse to child terms:
Janus Kinase 1
Janus Kinase 2
Janus Kinase 3
TYK2 Kinase
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