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Mesh term Thrombocytopenia, Neonatal Alloimmune

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Infant, Newborn, Diseases
Thrombocytopenia

Description

A condition in newborns caused by immunity of the mother to PLATELET ALLOANTIGENS on the fetal platelets. The PLATELETS, coated with maternal ANTIBODIES, are destroyed and removed by the fetal MONONUCLEAR PHAGOCYTE SYSTEM. Affected infants may have INTRACRANIAL HEMORRHAGES.



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