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Mesh term Cyclic Nucleotide Phosphodiesterases, Type 4

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3',5'-Cyclic-AMP Phosphodiesterases

Description

A cyclic nucleotide phosphodiesterase subfamily that is found predominantly in inflammatory cells and may play a role in the regulation of CELL-MEDIATED IMMUNITY. The enzyme family includes over twenty different variants that occur due to multiple ALTERNATIVE SPLICING of the mRNA of at least four different genes.



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