Medical College of Wisconsin
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Mesh term NAV1.5 Voltage-Gated Sodium Channel

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Voltage-Gated Sodium Channels

Description

A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function.



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