Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Mesh term Polycomb Repressive Complex 1

Browse to parent terms:
Polycomb-Group Proteins
Ubiquitin-Protein Ligases

Description

A multisubunit polycomb protein complex with affinity for CHROMATIN that contains methylated HISTONE H3. It contains an E3 ubiquitin ligase activity that is specific for HISTONE H2A and works in conjunction with POLYCOMB REPRESSIVE COMPLEX 2 to effect EPIGENETIC REPRESSION.



Search for this term in our Faculty Database



View this term at the NCBI website