Mesh term Mad2 Proteins
Browse to parent terms:Cell Cycle Proteins
Nuclear Proteins
Description
Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES.Search for this term in our Faculty Database
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