Medical College of Wisconsin
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Adrenal cortical carcinoma. World J Surg 2001 Jul;25(7):914-26

Date

09/27/2001

Pubmed ID

11572033

DOI

10.1007/s00268-001-0030-7

Scopus ID

2-s2.0-0034915765 (requires institutional sign-in at Scopus site)   295 Citations

Abstract

Adrenal cortical carcinoma is a rare endocrine tumor for which complete surgical resection is the only potentially curative treatment. Accurate preoperative evaluation (biochemical and radiographic) of the patient who presents with an adrenal mass maximizes the opportunity for the patient to undergo a complete, margin-negative resection of the primary tumor, which is the most powerful prognostic variable for long-term survival. The response to chemotherapy or mitotane is modest in patients with advanced disease. Hopefully, an improved understanding of the molecular pathogenesis of this challenging tumor will lead to the development of more effective therapies in the future.

Author List

Dackiw AP, Lee JE, Gagel RF, Evans DB

Author

Douglas B. Evans MD Chair, Professor in the Surgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adrenal Cortex
Adrenal Cortex Neoplasms
Adrenocortical Carcinoma
Humans
Radiography