Faculty Collaboration Database

Adenocarcinoma of the pancreas: current management of resectable and locally advanced disease. South Med J 1991 May;84(5):566-70

Date

05/01/1991

Pubmed ID

2035074

Scopus ID

2-s2.0-0025777556 (requires institutional sign-in at Scopus site)   24 Citations

Abstract

Surgical resection alone for patients with adenocarcinoma of the pancreas has rarely resulted in cure, and long-term survival is uncommon. The magnitude of the operation has historically prevented many patients from receiving multimodality therapy with systemic chemotherapy or radiation (external beam and intraoperative). Improved rates of operative morbidity and mortality, technical advances in intraoperative radiotherapy, and encouraging results from studies combining radiation and chemotherapy have renewed interest in innovative treatments for this disease. We review the rationale for the current management of patients with resectable and locally advanced adenocarcinoma of the pancreas and the current trial at The University of Texas M.D. Anderson Cancer Center.

Author List

Evans DB, Rich TA, Byrd DR, Ames FC

Author

Douglas B. Evans MD Chair, Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adenocarcinoma
Combined Modality Therapy
Fluorouracil
Humans
Intraoperative Period
Pancreatic Neoplasms
Tomography, X-Ray Computed