Faculty Collaboration Database

Association of airway abnormalities and risk factors in 37 subglottic stenosis patients. Otolaryngol Head Neck Surg 2006 Sep;135(3):434-7

Date

09/05/2006

Pubmed ID

16949978

DOI

10.1016/j.otohns.2006.04.013

Scopus ID

2-s2.0-33747891322 (requires institutional sign-in at Scopus site)   61 Citations

Abstract

OBJECTIVES: The study objective is to characterize the airway abnormalities in a series of patients with subglottic stenosis (SGS) as they relate to etiology and risk factors.

STUDY DESIGN AND SETTING: Retrospective review, academic medical center. Airway characteristics, patient demographics, and suspected risk factors were recorded from a database of SGS cases from 2001 to 2004.

RESULTS: Thirty-seven patients with SGS were identified; 22 of 37 had isolated SGS (59%). Intubation (10 of 37, 27%), high tracheotomy (4 of 37, 11%), and reflux (5 of 37, 14%) comprised the bulk of cases; 13 of 37 (35%) were considered idiopathic. Of 22 patients with isolated SGS, the majority 18 of 22 (P = 0.06) were women, 59% of which were idiopathic. Multiple-level cases (0 of 15) were idiopathic (P < 0.001). Intubation was the most common cause of multiple site stenosis (6 of 15, 40%).

CONCLUSIONS: The majority of patients in this study had isolated lesions. These patients tend to have no apparent risk factors. Multi-level cases are associated with prolonged intubation and known injuries. The nature of "idiopathic" stenoses is discussed.

SIGNIFICANCE: Clinical examination of SGS may be meaningful in understanding the etiology of the stenosis.

Author List

Poetker DM, Ettema SL, Blumin JH, Toohill RJ, Merati AL

Authors

Joel H. Blumin MD Chief, Professor in the Otolaryngology and Communication Sciences department at Medical College of Wisconsin
David M. Poetker MD Chief, Professor in the Otolaryngology and Communication Sciences department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Cohort Studies
Cough
Dyspnea
Female
Gastroesophageal Reflux
Glottis
Humans
Intubation, Intratracheal
Laryngoscopy
Laryngostenosis
Male
Middle Aged
Retrospective Studies
Risk Factors
Sex Factors
Tracheal Stenosis
Tracheotomy