Limited cell-cycle dependence of the merocyanine 540-sensitized photoinactivation of L1210 leukemia cells. Photochem Photobiol 1992 Aug;56(2):277-80
Date
08/01/1992Pubmed ID
1502271DOI
10.1111/j.1751-1097.1992.tb02158.xScopus ID
2-s2.0-0026903579 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
L1210 leukemia cells were synchronized by a double thymidine block technique and then characterized with regard to their susceptibility to merocyanine 540 (MC540)-sensitized photoinactivation. Cells harvested 5 (G2/M phase) h after release from the second thymidine block were most susceptible to MC540-sensitized photoinactivation followed, in order of decreasing sensitivity, by cells harvested 2 (S phase) h and by cells harvested 7 (G1 phase) h after release from the second block. The expression of dye-binding sites changed very little during the cell cycle.
Author List
Qiu K, Traul DL, Sieber FAuthor
Fritz Sieber PhD Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsCell Cycle
Leukemia L1210
Photochemotherapy
Pyrimidinones
Radiation-Sensitizing Agents
Tumor Cells, Cultured
