Morphological changes of Neisseria gonorrhoeae in amniotic fluid of pregnant women in their midtrimester. Acta Microbiol Hung 1992;39(1):21-30
Date
01/01/1992Pubmed ID
1632195Scopus ID
2-s2.0-0026486032 (requires institutional sign-in at Scopus site)Abstract
Ten selected samples of amniotic fluid obtained through transabdominal amniocentesis from 10 pregnant women in their 17th-19th weeks of pregnancy were investigated for the survival of Neisseria gonorrhoeae in amniotic fluid. In 8 cases an antibacterial effect was observed with morphological changes comparable to the effect of benzylpenicillin. When N. gonorrhoeae was inoculated in amniotic fluid at 10(5)-10(7) cells/ml, it survived as an average 2 h longer than after inoculation of 10(2)-10(4) cells/ml. Electron microscopic pictures of gonococci taken after 2.6 and 24 h incubation in amniotic fluid correlated with the growth curves. Electron microscopically there were marked morphologic changes of N. gonorrhoeae, viz. vacuolar degeneration of their cytoplasm with a damage to the bacterial wall up to its complete destruction and lysis of the cell.
Author List
Péc J, Mlyncek M, Moravcík P, Belej K, Lazárová ZMESH terms used to index this publication - Major topics in bold
Amniotic FluidFemale
Gonorrhea
Humans
Neisseria gonorrhoeae
Pregnancy
Pregnancy Complications, Infectious
Pregnancy Trimester, Second
