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Cyclic neutropenia in identical twins. Am J Med 1986 May;80(5):994-6

Date

05/01/1986

Pubmed ID

3706384

DOI

10.1016/0002-9343(86)90651-0

Scopus ID

2-s2.0-0022461244 (requires institutional sign-in at Scopus site)   4 Citations

Abstract

Cyclic neutropenia developed in identical twin girls. The onset of neutropenia in these children occurred three years apart. Neutrophil cycling diminished, and symptoms decreased in the initially affected twin during a five-year follow-up. Some cases of cyclic neutropenia may be genetically determined; however, the onset and clinical manifestations may be modified by other internal and external factors. There may also be a prodromal period during which neutrophils cycle, but the patient is neither neutropenic nor symptomatic.

Author List

Chusid MJ, Casper JT, Camitta BM, McCreadie SR

Authors

Bruce m. Camitta Professor in the Pediatrics department at Medical College of Wisconsin
James Casper MD Emeritus Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Agranulocytosis
Diseases in Twins
Female
Humans
Leukocyte Count
Neutropenia
Neutrophils
Periodicity
Time Factors
Twins, Monozygotic