Disease characteristics and psychosocial factors: explaining the expression of quality of life in childhood epilepsy. Epilepsy Behav 2010 May;18(1-2):88-93
Date
05/19/2010Pubmed ID
20478747DOI
10.1016/j.yebeh.2010.02.023Scopus ID
2-s2.0-77953915925 (requires institutional sign-in at Scopus site) 55 CitationsAbstract
OBJECTIVES: To explore, identify and understand the contribution that biomedical and psychosocial factors make to the assessment of health-related quality of life (HRQL) of children and youth with epilepsy using the CHEQOL-25.
METHODS: We identified and measured variables that may influence HRQL; grouped the variables into four conceptual categories; and used simple and hierarchical linear regressions to model CHEQOL-25 as a function of these variable groupings. Participants were 8-15year olds with epilepsy and their parents.
RESULTS: 131 child and parent pairs participated. Overall, the unique variances associated with the biomedical and psychosocial variables are R(2)=0.22 and 0.29, respectively, for child self-reported HRQL and R(2)=0.11 and 0.13, respectively, for parent-proxy report.
CONCLUSIONS: This study increases our understanding of factors that contribute to the expression of HRQL in this population. These results should be interpreted with caution due to the limited sample size and large number of variables.
Author List
Ronen GM, Streiner DL, Verhey LH, Lach L, Boyle MH, Cunningham CE, Rosenbaum PL, North American Pediatric Epilepsy QOL Research GroupMESH terms used to index this publication - Major topics in bold
AdolescentChild
Epilepsy
Female
Health Status
Humans
Linear Models
Male
Parents
Quality of Life
Severity of Illness Index
Surveys and Questionnaires
