Faculty Collaboration Database

The role of ultrasound in the surgical management of patients diagnosed with ductal carcinoma in situ of the breast. Breast J 2006;12(3):212-5

Date

05/11/2006

Pubmed ID

16684318

DOI

10.1111/j.1075-122X.2006.00244.x

Scopus ID

2-s2.0-33646265534 (requires institutional sign-in at Scopus site)   3 Citations

Abstract

The purpose of this study was to determine the usefulness of ultrasound (US) as an adjunct to mammography (MMG) in the surgical treatment planning for patients with ductal carcinoma in situ (DCIS) of the breast. A total of 119 patients diagnosed with DCIS, who were treated between 1999 and 2002, were identified from the institutional database. US and MMG size of suspicious abnormalities, pathologic tumor size, and findings of axillary US and surgical axillary evaluation were analyzed. The median size difference of US versus pathologic tumor size and MMG versus pathologic tumor size was 1.0 and 2.0 cm, respectively. Correlation coefficients for US versus pathologic tumor size and MMG versus pathologic tumor size were 0.53 and -0.09, respectively. The negative and positive predictive values of axillary US to predict nodal disease were 93% and 27%, respectively. US evaluation appears to be a useful tool in conjunction with MMG in determining the extent of disease in patients diagnosed with DCIS. However, the low positive predictive value of US for evaluating metastases to axillary lymph nodes does not justify the routine use of this modality for axillary evaluation in patients with DCIS. Therefore the use of US for patients diagnosed with DCIS needs further investigation.

Author List

Khakpour N, Zager JS, Yen T, Stephens T, Kuerer HM, Singletary ES, Ross MI, Hunt KK, Babiera GV

Author

Tina W F Yen MD, MS Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Aged
Aged, 80 and over
Breast Neoplasms
Carcinoma in Situ
Carcinoma, Ductal, Breast
Female
Humans
Mammography
Middle Aged
Observer Variation
Predictive Value of Tests
Reproducibility of Results
Ultrasonography