Use of irradiated lymphocytes from immune donors for treatment of disseminated varicella. J Pediatr 1994 Apr;124(4):593-6
Date
04/01/1994Pubmed ID
8151475DOI
10.1016/s0022-3476(05)83139-7Scopus ID
2-s2.0-0028221855 (requires institutional sign-in at Scopus site) 12 CitationsAbstract
Four children with acute lymphocytic leukemia who had disseminated varicella were treated with infusions of apheresed, irradiated lymphocytes from healthy donors who had recently recovered from infection with varicella-zoster virus. Each patient had cessation of new lesion formation and umbilication of old lesions within 24 hours of the first lymphocyte transfusion. There were no side effects attributable to the infusions. A controlled trial of infusions of irradiated lymphocytes should be considered for treatment of disseminated infection with varicella-zoster virus in immunocompromised hosts.
Author List
Camitta B, Chusid MJ, Starshak RJ, Gottschall JLMESH terms used to index this publication - Major topics in bold
ChickenpoxChild
Child, Preschool
Female
Humans
Immunocompromised Host
Lymphocyte Transfusion
Lymphocytes
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Tissue Donors
