Faculty Collaboration Database

Outcomes of acid suppressive therapy in patients with posterior laryngitis. Otolaryngol Head Neck Surg 2001 Jan;124(1):16-22

Date

03/03/2001

Pubmed ID

11228446

DOI

10.1067/mhn.2001.112200

Scopus ID

2-s2.0-0035142361 (requires institutional sign-in at Scopus site)   64 Citations

Abstract

OBJECTIVE: To evaluate the results of acid suppressive therapy (AST) in posterior laryngitis (PL) patients with and without documented pharyngeal acid reflux (PAR).

METHODS: The charts of all patients with PL who received AST and who had undergone pharyngeal pH monitoring were reviewed. Results of AST in patients with PL with and without documented PAR were evaluated by laryngeal examination, symptom scores, and self-reported overall benefit.

RESULTS: Thirty-nine patients with PL had received AST and undergone pharyngeal pH monitoring. Follow-up ranged from 2 to 27 months. Laryngeal findings were improved in patients with and without PAR. Pretreatment total symptom scores were significantly greater than that of posttreatment in patients with and without documented PAR. Overall benefit from AST was reported by the majority of PL patients with and without documented PAR.

CONCLUSION: These findings support the use of AST to reduce or eliminate signs and symptoms in PL regardless of documentation of PAR.

Author List

Ulualp SO, Toohill RJ, Shaker R

Author

Reza Shaker MD Assoc Provost, Sr Assoc Dean, Ctr Dir, Chief, Prof in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Aged
Anti-Ulcer Agents
Enzyme Inhibitors
Female
Follow-Up Studies
Gastric Acid
Gastroesophageal Reflux
Histamine H2 Antagonists
Humans
Hydrogen-Ion Concentration
Laryngitis
Male
Middle Aged
Proton Pump Inhibitors
Retrospective Studies
Severity of Illness Index