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CURRICULUM VITAE

Amanda Brandow DO
Professor
Department of Pediatrics
Division of Hematology and Oncology - Pediatrics

OFFICE ADDRESS:
MACC Fund Research Center
8701 Watertown Plank Rd
Milwaukee, WI 53226

EDUCATION:
1993 - 1997 BA, Drake University, Des Moines, IA
1997 - 2001 DO, Midwestern University, Chicago College of Osteopathic Medicine, IL
2006 - 2008 M.S., Epidemiology, Medical College of Wisconsin, Milwaukee, WI

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
07/2001 - 06/2004 Resident, Pediatrics, Medical College of Wisconsin, Milwaukee, WI
07/2004 - 06/2005 Chief Resident, Pediatrics, Medical College of Wisconsin, Milwaukee, WI
07/2005 - 07/2008 Fellow, Pediatrics, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI
2006 - 2008 Master's Degree, Epidemiology, Thesis emphasis on functional outcomes in children with Sickle Cell Disease, Medical College of Wisconsin, Milwaukee, WI

FACULTY APPOINTMENTS:
08/2008 - 06/2014 Assistant Professor, Pediatrics, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI
07/2014 - Present Associate Professor of Pediatrics, Department of Pediatrics, Section of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
Professor, Pediatrics, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI

EDUCATIONAL ADMINISTRATIVE APPOINTMENTS:
04/2013 - Present Pediatric Hematology Resident Elective Coordinator and Educational Liason, Pediatric, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI
04/2013 - Present Associate Fellowship Program Director, Pediatric Hematology/Oncology Fellowship Program, Pediatrics, Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:
08/2008 - Present Attending Physician, Hematology, Children's Hospital of Wisconsin, 9000 W Wisconsin Ave, Milwaukee, WI

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
General Pediatrics
10/2004
12/2016
Pediatric Hematology-Oncology
03/2009
03/2016
   
Licensure
Number Issue DateExpiration
Wisconsin License
46333-21
02/28/2021
    

AWARDS AND HONORS:
1997 Magna Cum Laude, Drake University
1998 - 2001 Sigma Sigma Phi, National Osteopathic Medical Honor Society
2006 Recipient of Loan Repayment Program in Pediatric Research, NIH
2008 Recipient of Loan Repayment Program in Pediatric Research, NIH
2008 Pediatric Fellow Clinical Research Award; 1st place, Medical College of Wisconsin
2010 Recipient of Loan Repayment Program in Pediatric Research, NIH
2011 Recipient of Loan Repayment Program in Pediatric Research, NIH
2012 Recipient of Loan Repayment Program in Pediatric Research, NIH
2013 Top-Rated Doctors, Metro Milwaukee (top 10% of rated doctors in the metro-Milwaukee area), M Magazine

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
2005 - Present American Society of Pediatric Hematology/Oncology
2005 - Present American Society of Hematology
2013 - Present American Pain Society

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
09/2009 British Journal of Haematology
01/2010 Pediatric Blood and Cancer
03/2010 British Journal of Haematology
04/2010 British Journal of Haematology
05/2010 British Journal of Haematology
12/2010 Journal of Pediatric Hematology/Oncology
01/2011 Pediatric Blood and Cancer
02/2011 Journal of Pediatric Hematology/Oncology
03/2011 Advances in Hematology
05/2011 Pediatric Blood and Cancer
01/2012 Jouranl of Pediatrics Hematology/oncology
07/2012 Journal of Pediatrics
10/2012 The Journal of Pain
11/2012 Journal of Pediatrics
01/2013 The Journal of Pain
01/2013 Journal of Pediatric Hematology/Oncology
01/2013 Journal of Pediatric Hematology/Oncology
02/2013 Pediatrics
02/2013 PLOS
03/2013 Journal of Pediatric Hematology/Oncology
04/2013 Acta Hematologica
04/2013 Journal of Genetic Counseling
05/2013 American Journal of Hematology
06/2013 Pediatrics
07/2013 Pediatrics
07/2013 Acta Hematologica
09/2013 Journal of Pediatrics
10/2013 Journal of Pediatric Hematology/Oncology
10/2013 The Journal of Pain
02/2014 Pediatrics
02/2014 Journal of Pediatric Hematology/Oncology

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
02/2014 - Present Reviewer, Patient Centered Unit Study Section, Children's Research Institute

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
10/2013 - Present Research Mentor, Clinical Resesarch Training Institute, American Society of Hematology

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
Pharmacokinetics and Relative Bioavailability of a Liquid Formulation of Hydroxyurea in Pediatric Patients with Sickle Cell Anemia
Source:
NIH/NICHD
Role:
Co-Investigator
Dates:
06/2012 - Present
  
Title:
Quantiative Assessment of Neuropathic Pain in Pediatric Oncology Patients Treated with Fincristine
Source:
Midwest Athletes Agains Childhood Cancer Novel Initiatives Award
Role:
Principal Investiagtor
Dates:
08/2012 - 08/2014
Direct Funds:
$29,075
  
Title:
Peripheral Sensitization as a Novel Mechanism for Pain in Sickle Cell Disease
Source:
NIH Loan Repayment Program in Pediatric Research (4th Renewal)
Role:
Principal Investigator
Dates:
08/2012 - 07/2014
Direct Funds:
$17,000 (To loan repayment)
  
Title:
Peripheral Sensitization as a Novel Mechanism for Pain in Patients with Sickle Cell Disease
Source:
NIH/NHLBI 1K23HL 114636-01A1
Role:
Principal Investigator
Dates:
08/15/2013 - 05/31/2018
Direct Funds:
$645,000
  
Title:
The Role of Substance P in the Pathophysiology of Pain in Patients with Sickle Cell Disease
Source:
American Society of Hematology Junior Faculty Scholar Award
Role:
Principal Investigator
Dates:
07/01/2014 - 06/30/2017
Direct Funds:
$150,000
  
Prior
Peer Review
Title:
Short-term Outcomes of Children with Sickle Cell Disease Treated for Vaso-Occlusive Crises
Source:
NIH Loan Repayment Program in Pediatric Research (initial award)
Role:
Principal Investigator
Dates:
07/2006 - 07/2008
Direct Funds:
$70,000 (to loan repayment)
  
Title:
Ruth L. Kirschstein National Research Service Award (NRSA)
Source:
NIH
Dates:
01/01/2008 - 06/30/2008
Direct Funds:
$49,190
  
Title:
Evaluation of Secondary and Tertiary Preventive Measures for Pain in Children with Sickle Cell Disease
Source:
NIH/NHLBI
Role:
Sickle Cell Scholar
PI:
Cheryl Hillery, MD
Dates:
06/15/2008 - 02/29/2012
Direct Funds:
$501,245
  
Title:
Utilization and Impact of Hydroxyurea in Children with Sickle Cell Disease
Source:
NIH Loan Repayment Program in Pediatric Research (1st renewal)
Role:
Principal Investigator
Dates:
07/2008 - 07/2010
Direct Funds:
$70,000 (to loan repayment)
  
Title:
Exploring Sensitivity to Pressure and Thermal Stimuli in Children with Sickle Cell Disease
Source:
NIH Loan Repayment Program in Pediatric Research (2nd renewal)
Role:
Principal Investigator
PI:
Amanda Brandow, DO
Dates:
07/2010 - 07/2011
Direct Funds:
$35,000 (to loan repayment)
  
Title:
Quantitative Sensory Testing in Humans with Sickle Cell Disease: A Pilot Study
Source:
Rebecca Slye Endowment (Children's Hospital of Wisconsin)
Role:
Principal Investigator
PI:
Amanda Brandow, DO
Dates:
01/2011 - 12/2011
Direct Funds:
$19,600
  
Title:
Clinically Meaningful Measurement of Pain in Children with Sickle Cell Disease
Source:
Rebecca Slye Endowment (Children’s Hospital of Wisconsin)
Role:
Co-Investigator
PI:
Matt Myrvik, PhD
Dates:
01/2011 - 12/2011
Direct Funds:
$16,000
  
Title:
Exploring Novel Pain Mechanisms in Humans with Sickle Cell Disease: Evaluation of Thermal Hypersensitivity and Identification of Risk Factors
Source:
NIH Loan Repayment Program in Pediatric Research (3rd renewal)
Role:
Principal Investigator
PI:
Amanda Brandow, DO
Dates:
08/2011 - Present
Direct Funds:
$35,000 (to loan repayment)
  
Non-Peer Review
Title:
The Effect of Montelukast on Markers of Neuorpathic Pain in Patients with Sickle Cell Disease
Source:
Children's Research Institute
Role:
Principal Investigator
Dates:
01/2014 - 12/2014
Direct Funds:
$41,000
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Women in Medicine: Work and Life Balance, American Medical Women’s Association, student chapter, Milwaukee, WI, 11/2005
Fever and Neutropenia, Children's Hospital of Wisconsin Hematology/Oncology Nursing Education Curriculum, Milwaukee, WI, 01/2006
Emergencies in Pediatric Leukemia, Children's Hospital of Wisconsin Transport Team Quarterly Educational Conference, Milwaukee, WI, 01/2007
Fever and Neutropenia, Children's Hospital of Wisconsin Hematology/Oncology Nursing Education Curriculum, Milwaukee, WI, 07/2007
Getting the Most out of Your First Year of Fellowship, Medical College of Wisconsin, Joint Fellowship Curriculum and Resident Retreat, Milwaukee, WI, 07/2007
Oncologic Emergencies, Children's Hospital of Wisconsin Hematology/Oncology Nursing Education, Milwaukee, WI, 08/2007
Pulmonary Complications of Sickle Cell Disease, Medical College of Wisconsin Sectionof PEdiatrifc Pulmonology Educational Seminar, Milwaukee, WI, 03/2009
Advancing the Care and Prevention of Pain in Children with Sickle Cell Disease, Children's Research Institute Academic Conference, Medical College of Wisconsin, Milwaukee, WI, 04/2009 - Present
Sickle Cell Disease Update: Focus on Pain Manifestation and Treatment, Wheaton Franciscan All Saints Hospital Grand Rounds - Yearly Sickle Cell Disease Lecture, Racine, WI, 05/2009
Hydroxyurea in Children with Sickle Cell Disease: Practice Patterns and Barriers to Utilization, Medical College of Wisconsin Epidemiology Seminar, Milwaukee, WI, 11/2009
Impact of Sickle Cell Disease on Health-related Quality of Life: Listening to the Voices of the Children, Wisconsin Association of Pediatric Hematology/Oncology Nurses (WAPHON) Quarterly Educational Conference, Milwaukee, WI, 11/2009
Impact of Sickle Cell Disease on Health-related Quality of Life: Listening to the Voices of the Children, Marquette Nursing Students, Milwaukee, WI, 03/2010
Novel Mechanisms of Pain in Sickle Cell Disease: A Bench to Bedside Approach, Medical College of Wisconsin Pediatric Hematology/Oncology Research Seminar, Milwaukee, WI, 03/2010
Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenia Purpura, Medical College of Wisconsin and Children's Hospital of Wisconsin Pediatric Critical Care Core Curriculum, Milwaukee, WI, 06/2011
Novel Mechanisms of Sickle Cell Pain: Thinking Outside the Sickled Cell, Children's Hospital of Wisconsin Grand Rounds, Milwaukee, WI, 10/2011
Pulmonary Complications of Sickle Cell Disease, Medical College of Wisconsin Section of Pediatric Pulmonology Educational Seminar, Milwaukee, WI, 01/2012
Ethics in Pediatric Pain Research, Medical College of Wisconsin, Milwaukee, WI, 06/2013
Sickle Cell Disease Emergencies, Medical College of Wisconsin/Children's Hospital of Wisconsin Pediatric Critical Care Core Curriculum, Milwaukee, WI, 06/2013
 
Regional
Women in Medicine: Work and Life Balance, American Medical Women's Association, Student Chapter, Milwaukee, WI, 11/2005
Impact of Sickle Cell Disease on Health-related Quality of Life: Listening to the Voices of the Children, Wisconsin Association of Pediatric Hematology/Oncology Nurses (WAPHYON) Quarterly Educational Conference, Milwauke, WI, 11/2008
Impact of Sickle Cell Disease on Health-related Quality of Life: Listening to the Voices of the Children, Wisconsin Association of Pediatric Hematology/Oncology Nurses (WAPHON) Quarterly Educational Conference, Milwaukee, WI, 11/2008
General Hematology, Wisconsin Association of Pediatric Hematology/Oncology Nurses (WAPHON) Board Review, Milwaukee, WI, 11/2010
Coagulation Disorders, Wisconsin Association of Pediatric Hematology/Oncology Nurses (WAPHON) Board Review, Milwaukee, WI, 11/2010
Anemia: Evaluation and Management for Primary Care Pediatricians, Children's Specialty Group/Children's Hospital of Wisconsin CME Podcast, Milwaukee, WI, 01/2012
Anemia: Evaluation and Mangement for Primary Care Pediatrician, Children's Specialty Group/Children's Hospital of Wisconsin CME Podcast, Wisconsin Dells, WI, 03/2015
 
National
Functional Outcomes of Children with Sickle Cell Disease Treated for Vaso-occlusive Painful Events, Memorial Healthcare System’s 2nd Annual National Sickle Cell Disease Research and Educational Symposium, Fort Lauderdale, FL, 02/2008
Evaluation of Secondary and Tertiary Preventive Measures for Pain in Children with Sickle Cell Disease, Sickle Cell Disease Clinical Research Meetings (NIH), Bethesda, MD, 08/2009
The Impact of a Multidisciplinary Pain Management Model on Sickle Cell Disease Hospitalizations, Sickle Cell Disease Clinical Research Meetings (NIH), Bethesda, MD, 08/2010
Anemia: Evaluation and Management for Primary Care Pediatricians, 54th Annual Pediatric Clinic Days sponsored by Children’s Hospital of Michigan, Detroit, MI, 10/2011
Establishing a Career in Patient Oriented Research, Young Investigator Workshop: A Research Career Starter. American Society of Pediatric Hematology/Oncology Annual Meeting, New Orleans, LA, 05/2012
 

PEER REVIEWED WORKSHOPS/PRESENTATIONS:
National
Brandow AM, Hansen S, Greenbaum LA, Vitamin D Deficient Rickets Presenting as Cardiopulmonary Arrest, American Academy of Pediatrics Annual Meeting - Poster Presentation, San Francisco, CA, 10/2004
Brandow AM, Rennie K, Scott JP, Hillery CA, Panepinto JA, Increased Red Blood Cell Adhesion is Associated with Priapism in Sickle Cell Disease, American Society of Hematology Annual Meeting - Poster Presentation, Orlando, FL, 12/2006
Brandow AM, Brousseau DC, Panepinto JA, Functional Outcomes of Children with Sickle Cell Disease Treated for Vaso-occlusive Painful Events, American Society of Hematology Annual Meeting - Oral Presentation, Atlanta, GA, 12/2007
Wandersee NJ, Uy T, Retherford D, Noon-Abdullah A, Frei AC, Brandow AM, Stucky CL, Hillery CA, Mechanical Hypersensitivity Occurs in a Mouse Model of Sickle Cell Disease, American Society of Hematology Annual Meeting - Poster Presentation, San Francisco, CA, 12/2008
Brandow AM, Jirovec DL, Panepinto JA, Hydroxyurea in Children with Sickle Cell Disease: Practice Patterns and Barriers to Utilization, American Society of Hematology Annual Meeting - Oral Presentation, New Orleans, LA, 12/2009
Brandow AM and Panepinto JA, Evaluation of Children with Sickle Cell Disease Treated for Chronic or Recurrent Pain using a Multidimensional Pain Management Model, American Society of Pediatric Hematology Oncology Annual Meeting - Poster Presentation, Montreal, Canada, 04/2010
Epping A, Jirovec DL, Newby RF, Panepinto JA, Brandow AM, Scott JP, Transitional Care: Educational and Employment Outcomes of Adults with Sickle Cell Disease, American Society of Pediatric Hematology Oncology Annual Meeting - Poster Presentation, Montreal, Canada, 04/2010
Epping A, Newby RF, Panepinto JA, Brandow AM, Jirovec DL, Scott JP, Patterns of Academic Achievement in Children with Sickle Cell Disease, American Society of Pediatric Hematology Oncology Annual Meeting - Poster Presentation, San Diego, CA, 12/2010
Brandow AM and Panepinto JA, Monitoring Hydroxyurea in Children with Sickle Cell Disease: Results of a National Provider Survey, Sickle Cell Disease Symposium and Scientific Meeting - Oral Presentation, Fort Lauderdale, FL, 02/2011
Brandow AM, Kattappuram R, Panepinto JA, Hydroxyurea Effectively Decreases the Probability of Acute Chest Syndrome in Children with Sickle Cell Disease, American Society of Pediatric Hematology Oncology Annual Meeting - Poster Presentation, Baltimore, MD, 04/2011
Brandow AM, Kattappuram R, Hillery CA, Stucky CL, Panepinto JA, Patients with sickle cell disease have increased sensitivity to cold and heat stimuli., American Society of Hematology Annual Meeting, San Diego, CA, 12/2011
Brandow AM, Farley RA, Panepinto JA, Existence of neuropathic pain in patines with sickle cell disease, American Society of Hematology Annual Meeting, Atlanta, GA, 12/2012
Myrvik MP, Brandow Am, Drendel Al, Hoffman RG, Yank K, Panepinto JA, Clinically meaningful measurement of pain in children with sickle cell disease, 7th Annual Sickle Cell Disease Research and Educational Symposium/National Sickle Cell Disease Scientific Meeting, Miami, FL, 04/2013
Brandow AM, Farley RA, Hoffmann RG, Panepinto JA, Teh use of neuopathic pain drugs in patients with sic kle cell disease is associated with older age and female gender, American Society of Hematology Annual Meeting, New Orleans, LA, 12/2013
Green NS, Thornburg C, Brandow AM, Sharma M, Bekele E, Smaldone A, Are difficulties in taking medication an impediment for children to use hydroxyurea?, American Society of Hematology Annual Meeting, New Orleans, LA, 12/2013
 
International
Brandow AM, Panepinto JA, The Impact of Vaso-occlusive Painful Events on the Health Related Quality of Life of Children with Sickle Cell Disease, International Society of Quality of Life Annual Meeting - Poster Presentation, Montevideo, Uruguay, 10/2008
 

COMMITTEE SERVICE:
Medical College of Wisconsin
2004 - 2005 Residency Selection Committee, Pediatrics, Medical College of Wisconsin
2006 - 2007 Residency Selection Committee, Pediatrics, Medical College of Wisconsin
2007 Participated in Curriculum Design for 2007-2008, Joint Fellowship Curriculum Committee, Pediatrics, Medical College of Wisconsin
2013 Member, Clinical Research Scholars Program Selection Committee Clinical and Translational Sciences Institute, Pediatrics, Medical College of Wisconsin
2013 Member, Faculty Scholarly Evaluation Committee, Hematology/Oncology/BMT, Pediatrics, Medical College of Wisconsin
2013 Member, Children's Specialty Group Professional Development Committee, Pediatrics, Medical College of Wisconsin
2013 - 2014 Member, Fellowship Committee, Hematology/Oncology/BMT, Pediatrics, Medical College of Wisconsin
2013 Member, Physician-Scientist Pathway Council, Pediatrics, Medical College of Wisconsin
2013 - Present Member, Joint Fellowship Curriculum Committee, Pediatrics, Medical College of Wisconsin
06/2014 - Present Member, Program Evaluation Committee, Hematology/Oncology/BMT, Pediatrics, Medical College of Wisconsin
06/2014 - Present Member, Clinical Competency Committee, Hematology/Oncology/BMT, Pediatrics, Medical College of Wisconsin
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Student Education
11/2005 American Medical Women’s Association, Student Chapter - Women in Medicine: Work and Life Balance
2005 Medical Interviewing Class - 8 week class for M1 students on conducting appropriate medical interviews using simulated patients
2008 Biochemistry case-based discussion, "Sickle Cell Disease"
2010 - 2011 Physician Scientist Pathway Small Group Facilitator (Spring Quarter) - Facilitated small group discussion revolving around clinical research skills
2012 Biochemistry case-based discussion, "Sickle Cell Disease"
2013 M1 Foundations of Clinical Medicine Course, Guest Facilitator, "How to Take a Pain History" (using a standardized patient with sickle cell disease)
 
Resident and Fellow Education
2004 - 2005 Professors’ Rounds - Led case based presentations and discussions for entire pediatric residency program and faculty
2004 - 2005 General Pediatric Ward Teaching Attending - conducted daily teaching attending rounds for 3-4 pediatric residents on the inpatient general pediatric ward team (2 months)
2004 - 2005 Senior Resident Morning Report - assisted in morning report for senior residents rotating on the inpatient pediatric service (12 months)
07/2007 Joint Fellowship Curriculum and Resident Retreat - Getting the Most out of your First Year of Fellowship
2008 - 2011 Pediatric Hematology/Oncology Fellowship Lecture Series - Thalassemia
2008 - 2009 Pediatric Hematology/Oncology Fellowship Lecture Series - Sickle Cell Disease
2009 - 2010 General Pediatric Ward Teaching Attending - Conducted daily teaching attending rounds for 3-4 pediatric residents on the inpatient general pediatric ward team (1 month)
2010 Clinical and Translational Science Institute Translational Human Genetics Course: Hemoglobinopathies
2010 Joint Fellowship Curriculum - Career Development Panel
2010 - 2011 Pediatric Sub-specialty Panel - Participated in Pediatric Special Interest Group’s panel discussion about subspecialty careers in pediatric medicine
07/2011 Pediatric Residency Lecture Series - Sickle Cell Disease
2011 Clinical and Translational Science Institute Translational Human Genetics Course: Hemoglobinopathies
2011 Pediatric Resident Noon Conference Lecture Series: Sickle Cell Disease, Anemia, Novel Mechanisms of Pain in Sickle Cell Disease
2011 Pediatric Resident Journal Club Facilitator PL3 Journal Club
2012 Pediatric Resident Journal Club Facilitator - PL3 Journal Club
2012 Pediatric Resident Noon Conference Lecture Series: Sickle Cell Disease, Anemia, Novel Mechanisms of Pain in Sickle Cell Disease
2012 Clinical and Translational Science Institute Translational Human Genetics Course: Hemoglobinopathies
2013 Pediatric Resident Noon Conference Lecture Series: Sickle Cell Disease, Anemia, Novel Mechanisms of Pain in Sickle Cell Disease
2013 Pediatric Resident Journal Club Faciliator - PL3 Journal Club
 
Continuing Medical Education
01/2006 - 07/2007 Hematology/Oncology Nursing Education Curriculum - Fever and Neutropenia
01/2007 - 09/2007 Transport Team Quarterly Educational Conference - Emergencies in Pediatric Leukemia
08/2007 Hematology/Oncology Nursing Education Curriculum - Oncologic Emergencies
12/15/2008 - 12/16/2008 Wisconsin Regional Transport Team Conference Simulation Lab Facilitator - Hematologic Emergencies
03/2009 Pediatric Pulmonology Educational Seminar - Pulmonary Complications of Sickle Cell Disease
04/2009 Children’s Research Institute Academic Conference - Advancing the Care and Prevention of Pain in Children with Sickle Cell Disease
11/2009 - 03/2010 Marquette Nursing Students Lecture - Impact of Sickle Cell Disease on Health-related Quality of Life: Listening to the Voices of the Children
11/2009 Epidemiology Seminar - Hydroxyurea in Children with Sickle Cell Disease: Practice Patterns and Barriers to Utilization
03/2010 Pediatric Hematology/Oncology Research Seminar - Novel Mechanisms of Pain in Sickle Cell Disease: A Bench to Bedside Approach
06/2011 Pediatric Critical Care Core Curriculum - Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenia Purpura
 
Graduate Student Education
2013 Clinical and Translational Science Institute Translational Human Genetics Course: Hemoglobinopathies
 

EXTRAMURAL TEACHING:
Medical Student Education
2004 - 2005 Medical College of Wisconsin/Children's Hospital of Wisconsin, General Pediatric Ward Teaching Attending - Conducted daily teaching attending rounds for 3-4 students on the inpatient general pediatric ward team (2 months)
2009 - 2010 Medical College of Wisconsin/Children's Hospital of Wisconsin, General Pediatric Ward Teaching Attending - Conducted daily teaching attending rounds for 3-4 students on the inpatient general pediatric ward team (1 month)
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
Nicholas Tadeo, Medical College of Wisconsin, 2013 - 2014 Clinical Advisor
Emily Roth, Medical College of Wisconsin, 2013 - 2014 Clinical Advisor
 
Residents
Matthew Ehrhardt, MD, Peds: Heme/Onc/BMT Fellow, Medical College of Wisconsin, 2012 - 2014 Scholarly Oversight Committee Member
 

CAREER DEVELOPMENT ACTIVITIES:
08/2009 - 08/2010 American Society of Hematology Clinical Research Training Institute - One of 20 selected to participate in this year-long education and mentoring program focused on training hematologists for careers in clinical research.
09/2009 - 09/2011 K30 Clinical Research Scholars Program, Medical College of Wisconsin - One of 12 selected to participate in the NIH sponsored program with the goal of training junior faculty for a successful career in clinical research.


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Kam J, Panepinto JA, Brandow AM, Brousseau DC. Parental perception of quality of hospital care for children with sickle cell disease. WMJ. 2008 May;107(3):131-5.
2. Brandow AM, Brousseau DC, Panepinto JA. Postdischarge pain, functional limitations and impact on caregivers of children with sickle cell disease treated for painful events. Br J Haematol. 2009 Mar;144(5):782-8. PMCID: PMC3118502
3. Brousseau DC, Mukonje T, Brandow AM, Nimmer M, Panepinto JA. Dissatisfaction with hospital care for children with sickle cell disease not due only to race and chronic disease. Pediatr Blood Cancer. 2009 Aug;53(2):174-8.
4. Brandow AM, Brousseau DC, Pajewski NM, Panepinto JA. Vaso-occlusive painful events in sickle cell disease: impact on child well-being. Pediatr Blood Cancer. 2010 Jan;54(1):92-7. PMCID: PMC3114448
5. Brandow AM, Jirovec DL, Panepinto JA. Hydroxyurea in children with sickle cell disease: practice patterns and barriers to utilization. Am J Hematol. 2010 Aug;85(8):611-3. PMCID: PMC2911651
6. Brandow AM, Weisman SJ, Panepinto JA. The impact of a multidisciplinary pain management model on sickle cell disease pain hospitalizations. Pediatr Blood Cancer. 2011 May;56(5):789-93. PMCID: PMC3069506
7. Brandow AM, Liem R. "Sickle Cell Disease in the Emergency Department: Atypical Complications and Management". Clin Pediatr Emerg Med. 2011 Sep 01;12(3):202-212. PMCID: PMC3172721
8. Brandow AM, Panepinto JA. Monitoring toxicity, impact, and adherence of hydroxyurea in children with sickle cell disease. Am J Hematol. 2011 Sep;86(9):804-6. PMCID: PMC3804029
9. Hillery CA, Kerstein PC, Vilceanu D, Barabas ME, Retherford D, Brandow AM, Wandersee NJ, Stucky CL. Transient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease. Blood. 2011 Sep 22;118(12):3376-83. PMCID: PMC3179403
10. Brandow AM, Stucky CL, Hillery CA, Hoffmann RG, Panepinto JA. Patients with sickle cell disease have increased sensitivity to cold and heat. Am J Hematol. 2013 Jan;88(1):37-43. PMCID: PMC3552380
11. Anderson C, Torres S, Gokuli S, Brandow AM, Panepinto JA. Assessment of communication modes in patients and families with sickle cell disease. Pediatr Blood Cancer. 2013 May;60(5):887.
12. Epping AS, Myrvik MP, Newby RF, Panepinto JA, Brandow AM, Scott JP. Academic attainment findings in children with sickle cell disease. J Sch Health. 2013 Aug;83(8):548-53.
13. Myrvik MP, Brandow AM, Drendel AL, Yan K, Hoffmann RG, Panepinto JA. Clinically meaningful measurement of pain in children with sickle cell disease. Pediatr Blood Cancer. 2013 Oct;60(10):1689-95. PMCID: PMC3993972
14. Brandow AM, Farley RA, Panepinto JA. Neuropathic pain in patients with sickle cell disease. Pediatr Blood Cancer. 2014 Mar;61(3):512-7. PMCID: PMC4357477
15. Dobrozsi, S, Flood V, Panepinto JA, Scott JP, Brandow AM. Vitamin B12 deficiency: the great masquerader. Pediatr Blood Cancer 2014; 61:753-5.
16. Bekele E, Thornburg CD, Brandow AM, Sharma M, Smaldone AM, Jin Z, Green NS. Do difficulties in swallowing medication impede the use of hydroxyurea in children? Pediatr Blood Cancer. 2014 Sep;61(9):1536-9. PMCID: PMC4184198
17. Myrvik MP, Drendel AL, Brandow AM, Yan K, Hoffmann RG, Panepinto JA. A Comparison of Pain Assessment Measures in Pediatric Sickle Cell Disease: Visual Analog Scale Versus Numeric Rating Scale. J Pediatr Hematol Oncol. 2015 Apr;37(3):190-4.
18. Wong TE, Brandow AM, Lim W, Lottenberg R. Update on the use of hydroxyurea therapy in sickle cell disease. Blood. 2014 Dec 18;124(26):3850-7; quiz 4004. PMCID: PMC4271176
19. Brandow AM, Farley RA, Dasgupta M, Hoffmann RG, Panepinto JA. The use of neuropathic pain drugs in children with sickle cell disease is associated with older age, female sex, and longer length of hospital stay. J Pediatr Hematol Oncol. 2015 Jan;37(1):10-5. PMCID: PMC4270887
20. Brandow AM, Farley RA, Panepinto JA Early insights into the neurobiology of pain in sickle cell disease: A systematic review of the literature. Pediatr Blood Cancer. 2015 May 13:doi: 10.1002/pbc.25574 PMID:25976161
21. Estepp JH, Melloni C, Thornburg CD, Wiczling P, Rogers Z, Rothman JA, Green NS, Liem R, Brandow AM, Crary SE, Howard TH, Morris MH, Lewandowski A, Garg U, Jusko WJ, Neville KA, Best Pharmaceuticals for Children Act-Pediatric Trials Network Administrative Core Committee. Pharmacokinetics and bioequivalence of a liquid formulation of hydroxyurea in children with sickle cell anemia. J Clin Pharmacol. 2016 Mar;56(3):298-306. PMCID: PMC4892120
22. Brandow AM, Panepinto JA. Clinical Interpretation of Quantitative Sensory Testing as a Measure of Pain Sensitivity in Patients With Sickle Cell Disease. J Pediatr Hematol Oncol. 2016 May;38(4):288-93. PMCID: PMC4856159
23. Brandow AM, Nimmer M, Simmons T, Charles Casper T, Cook LJ, Chumpitazi CE, Paul Scott J, Panepinto JA, Brousseau DC. Impact of emergency department care on outcomes of acute pain events in children with sickle cell disease. Am J Hematol. 2016 Dec;91(12):1175-1180.
24. Brandow AM et al. The impact of a multidisciplinary pain management model on sickle cell disease pain hospitalizations. Pediatr Blood Cancer. 2010 Dec 15:
25. Brandow AM, Farley RA, Panepinto JA. Early insights into the neurobiology of pain in sickle cell disease: A systematic review of the literature. Pediatr Blood Cancer. 2015 Sep;62(9):1501-11. PMCID: PMC4515148
26. Brandow AM, Wandersee NJ, Dasgupta M, Hoffmann RG, Hillery CA, Stucky CL, Panepinto JA. Substance P is increased in patients with sickle cell disease and associated with haemolysis and hydroxycarbamide use. Br J Haematol. 2016 Oct;175(2):237-245. PMCID: PMC5063705
27. Acquazzino MA, Igler EC, Dasgupta M, Simpson P, Browning MB, Brandow AM. Patient-reported neuropathic pain in adolescent and young adult cancer patients. Pediatr Blood Cancer. 2017 Mar;64(3).
28. Brandow AM, Zappia KJ, Stucky CL. Sickle cell disease: a natural model of acute and chronic pain. Pain. 2017 Apr;158 Suppl 1(Suppl 1):S79-S84. PMCID: PMC5350013
29. Darbari DS, Brandow AM. Pain-measurement tools in sickle cell disease: where are we now? Hematology Am Soc Hematol Educ Program. 2017 Dec 08;2017(1):534-541. PMCID: PMC6142608
30. Curtis S, Brandow AM. Responsiveness of Patient-Reported Outcome Measurement Information System (PROMIS) pain domains and disease-specific patient-reported outcome measures in children and adults with sickle cell disease. Hematology Am Soc Hematol Educ Program. 2017 Dec 08;2017(1):542-545. PMCID: PMC6142574
31. Brandow AM, DeBaun MR. Key Components of Pain Management for Children and Adults with Sickle Cell Disease. Hematol Oncol Clin North Am. 2018 Jun;32(3):535-550. PMCID: PMC6800257
32. Hankins JS, Estepp JH, Hodges JR, Villavicencio MA, Robison LL, Weiss MJ, Kang G, Schreiber JE, Porter JS, Kaste SC, Saving KL, Bryant PC, Deyo JE, Nottage KA, King AA, Brandow AM, Lebensburger JD, Adesina O, Chou ST, Zemel BS, Smeltzer MP, Wang WC, Gurney JG. Sickle Cell Clinical Research and Intervention Program (SCCRIP): A lifespan cohort study for sickle cell disease progression from the pediatric stage into adulthood. Pediatr Blood Cancer. 2018 Sep;65(9):e27228.
33. Brandow AM, Hansen K, Nugent M, Pan A, Panepinto JA, Stucky CL. Children and adolescents with sickle cell disease have worse cold and mechanical hypersensitivity during acute painful events. Pain. 2019 Feb;160(2):407-416. PMCID: PMC6768435
34. Asnani MR, Francis DK, Brandow AM, Hammond Gabbadon CE, Ali A. Interventions for treating neuropathic pain in people with sickle cell disease. Cochrane Database Syst Rev. 2019 Jul 05;7(7):CD012943. PMCID: PMC6609827
35. Sadler KE, Langer SN, Menzel AD, Moehring F, Erb AN, Brandow AM, Stucky CL. Gabapentin alleviates chronic spontaneous pain and acute hypoxia-related pain in a mouse model of sickle cell disease. Br J Haematol. 2019 Oct;187(2):246-260. PMCID: PMC6786911
36. Karafin MS, Chen G, Wandersee NJ, Brandow AM, Hurley RW, Simpson P, Ward D, Li SJ, Field JJ. Chronic pain in adults with sickle cell disease is associated with alterations in functional connectivity of the brain. PLoS One. 2019;14(5):e0216994. PMCID: PMC6527293
37. Singh A, Yan K, Brandow AM, Panepinto JA. Longitudinal Trend in Emergency Department Reliance for Pain Among Sickle Cell Disease Patients in Wisconsin. J Pediatr Hematol Oncol. 2019 Oct;41(7):e438-e442.
38. Murad MH, Liem RI, Lang ES, Akl EA, Meerpohl JJ, DeBaun MR, Tisdale JF, Brandow AM, Lanzkron SM, Chou ST, Webb S, Mustafa RA. 2019 sickle cell disease guidelines by the American Society of Hematology: methodology, challenges, and innovations. Blood Adv. 2019 Dec 10;3(23):3945-3950. PMCID: PMC6963245
39. Sharma D, Brandow AM. Neuropathic pain in individuals with sickle cell disease. Neurosci Lett. 2020 Jan 01;714:134445.
40. Farrell AT, Panepinto J, Carroll CP, Darbari DS, Desai AA, King AA, Adams RJ, Barber TD, Brandow AM, DeBaun MR, Donahue MJ, Gupta K, Hankins JS, Kameka M, Kirkham FJ, Luksenburg H, Miller S, Oneal PA, Rees DC, Setse R, Sheehan VA, Strouse J, Stucky CL, Werner EM, Wood JC, Zempsky WT. End points for sickle cell disease clinical trials: patient-reported outcomes, pain, and the brain. Blood Adv. 2019 Dec 10;3(23):3982-4001. PMCID: PMC6963237
41. Brandow AM, Carroll CP, Creary S, Edwards-Elliott R, Glassberg J, Hurley RW, Kutlar A, Seisa M, Stinson J, Strouse JJ, Yusuf F, Zempsky W, Lang E. American Society of Hematology 2020 guidelines for sickle cell disease: management of acute and chronic pain. Blood Adv. 2020 Jun 23;4(12):2656-2701. PMCID: PMC7322963
42. Curtis SA, Brandow AM, DeVeaux M, Zeltermam D, Devine L, Roberts JD. Daily Cannabis Users with Sickle Cell Disease Show Fewer Admissions than Others with Similar Pain Complaints. Cannabis Cannabinoid Res. 2020;5(3):255-262. PMCID: PMC7480712
43. Román ME, Highland J, Retherford D, Pan AY, Panepinto JA, Brandow AM. Neuropathic pain is associated with poor health-related quality of life in adolescents with sickle cell disease: A preliminary report. Pediatr Blood Cancer. 2020 Dec;67(12):e28698.
44. Glaros A, Brandow AM. Neuropathic pain in sickle cell disease: measurement and management. Hematology Am Soc Hematol Educ Program. 2020 Dec 04;2020(1):553-561. PMCID: PMC7727515
45. Singh A, Danda V, Van Swol L, Scott JP, Brandow AM, Panepinto JA. Recommendation to reality: Closing the transcranial Doppler screening gap for children with sickle cell anemia. Pediatr Blood Cancer. 2021 Feb;68(2):e28831.
46. Singh A, Brandow AM, Panepinto JA. COVID-19 in individuals with sickle cell disease/trait compared with other Black individuals. Blood Adv. 2021 Apr 13;5(7):1915-1921. PMCID: PMC8015795
47. Mucalo L, Brandow AM, Dasgupta M, Mason SF, Simpson PM, Singh A, Taylor BW, Woods KJ, Yusuf FI, Panepinto JA. Comorbidities are risk factors for hospitalization and serious COVID-19 illness in children and adults with sickle cell disease. Blood Adv. 2021 Jul 13;5(13):2717-2724. PMCID: PMC8248962
48. Rampersaud E, Kang G, Palmer LE, Rashkin SR, Wang S, Bi W, Alberts NM, Anghelescu D, Barton M, Birch K, Boulos N, Brandow AM, Brooke RJ, Chang TC, Chen W, Cheng Y, Ding J, Easton J, Hodges JR, Kanne CK, Levy S, Mulder H, Patel AP, Puri L, Rosencrance C, Rusch M, Sapkota Y, Sioson E, Sharma A, Tang X, Thrasher A, Wang W, Yao Y, Yasui Y, Yergeau D, Hankins JS, Sheehan VA, Downing JR, Estepp JH, Zhang J, DeBaun M, Wu G, Weiss MJ. A polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease. Blood Adv. 2021 Jul 27;5(14):2839-2851. PMCID: PMC8341359
49. Curtis SA, Raisa BM, Roberts JD, Hendrickson JE, Starrels J, Lesley D, Michelle D, Daniel Z, Brandow AM. Non-crisis related pain occurs in adult patients with sickle cell disease despite chronic red blood cell exchange transfusion therapy. Transfus Apher Sci. 2022 Apr;61(2):103304. PMCID: PMC9838733
50. Brandow AM, Liem RI. Advances in the diagnosis and treatment of sickle cell disease. J Hematol Oncol. 2022 Mar 03;15(1):20. PMCID: PMC8895633
51. Strouse JJ, Brandow AM. Web Exclusive. Annals for Hospitalists Inpatient Notes - Clinical Pearls-Acute Pain Episodes in Sickle Cell Disease. Ann Intern Med. 2022 Mar;175(3):HO2-HO3.
52. Singh A, Brandow AM, Wun T, Shet AS. COVID-19 and venous thromboembolism risk in patients with sickle cell disease. Blood Adv. 2022 Aug 09;6(15):4408-4412. PMCID: PMC9239700
53. Carroll CP, Brandow AM. Chronic Pain: Prevalence and Management. Hematol Oncol Clin North Am. 2022 Dec;36(6):1151-1165.
54. Mucalo L, Brandow AM, Singh A. A perspective on the sickle cell disease international COVID-19 registry. Best Pract Res Clin Haematol. 2022 Sep;35(3):101385. PMCID: PMC9509018
55. Allison RL, Burand A, Torres DN, Brandow AM, Stucky CL, Ebert AD. Sickle cell disease patient plasma sensitizes iPSC-derived sensory neurons from sickle cell disease patients. bioRxiv. 2023 Jan 10. PMCID: PMC9882050
56. Singh A, Dasgupta M, Retherford D, Baker M, Hulihan M, Brandow AM. Surveillance for the Rare Condition of Sickle Cell Disease in Wisconsin. WMJ. 2022 Dec;121(4):297-300. PMCID: PMC10026077
57. Mucalo L, Field JJ, Highland J, Khan H, Hankins JS, Singh A, Brandow AM. Preliminary construct validity of patient-reported outcomes to assess chronic pain in adults with sickle cell disease. Blood Adv. 2023 Jul 25;7(14):3658-3665. PMCID: PMC10365933
58. Sadler KE, Atkinson SN, Ehlers VL, Waltz TB, Hayward M, Rodríguez García DM, Salzman NH, Stucky CL, Brandow AM. Gut microbiota and metabolites drive chronic sickle cell disease pain. bioRxiv. 2023 Apr 28. PMCID: PMC10168372
 
Books, Chapters, and Reviews
1. Cohen G, Brandow AM. Jaundiced Newborn. On-line Nelson's 18th Edition. www.nelsonpediatrics.com.
2. Camitta B, Brandow AM. Primary Polycythemia. Nelson Textbook of Pediatrics 19th Edition.
3. Camitta B, Brandow AM. Secondary Polycythemia. Nelson Textbook of Pediatrics 19th Edition.
4. Camitta B, Brandow AM. Anatomy and Function of the Spleen. Nelson Textbook of Pediatrics 19th Edition.
5. Camitta B, Brandow AM. Splenomegaly. Nelson Textbook of Pediatrics 19th Edition.
6. Camitta B, Brandow AM. Hypersplenism, Splenic Trauma, and Splenectomy. Nelson Textbook of Pediatrics 19th Edition.
7. Brandow AM, Camitta B. Primary Polycythemia. Nelson Textbook of Pediatrics 20th Edition.
8. Brandow AM, Camitta B. Primary Polycythemia; Secondary Polycythemia; Anatomy and Function of the Spleen; Splenomegaly; Hypersplenism, Splenic Trauma, and Splenectomy. Nelson Textbook of Pediatrics 20th Edition. 2011.
 
Editorials, Letters to Editor, Other
1. Brandow AM, Panepinto JA. Hydroxyurea use in sickle cell disease: the battle with low prescription rates, poor patient compliance and fears of toxicities. Expert Rev Hematol. 2010 Jun;3(3):255-60. PMCID: PMC3793890
2. Brandow AM. Book Review: Neonatal Hematology: Pathogenesis, Diagnosis, and Management of Hematologic Problems. J Pediatr Hematol Oncol (in press, 2013).
 
Non-Refereed Journal Publications/Original Papers
1. Brandow AM. Acute Painful Events in Children with Sickle Cell Disease. Pediatric Rounds (Children's Hospital of Wisconsin Publication); January 2010.
 
Abstracts
1. Brandow AM, Punzalan RC, Stephany K, Helsell C, Gill JC. Novel Treatment Approaches in Combination with Rituximab for Immune Tolerance Induction in Severe Hemophilia B. Blood 2007;110(11):61B.
2. Brandow AM, Brousseau DC, Panepinto JA. Functional Outcomes of Children with Sickle Cell Disease Treated for Vaso-occlusive Painful Events. Blood 2007;110(11):33a.
3. Brandow AM, Jirovec DL, Panepinto JA. Hydroxyurea in Children with Sickle Cell Disease: Practice Patterns and Barriers to Utilization. Blood 2009; 114:242
4. Brandow AM, Hansen S, Greenbaum LA. Vitamin D Deficient Rickets Presenting as Cardiopulmonary Arrest. Pediatric Critical Care Medicine 2004;5:511
5. Brandow AM, Hansen S, Greenbaum LA. Vitamin D Deficient Rickets Presenting as Cardiopulmonary Arrest. Pediatric Critical Care Medicine 2004;5:511.
6. Brandow AM, Rennie K, Scott JP, Hillery CA, Panepinto JA. Increased Red Blood Cell Adhesion is Associated with Priapism in Sickle Cell Disease. Blood 2006;108(11):363a.
7. Brandow AM, Panepinto JA. The Impact of Vaso-occlusive Painful Events on the Health Related Quality of Life of Children with Sickle Cell Disease. The Quality of Life Research Journal 2008, A-42, Abstract #1789.
8. Wandersee NJ, Uy T, Retherford D, Noon-Abdullah A, Frei AC, Brandow AM, Stucky CL, Hillery CA. Mechanical Hypersensitivity Occurs in a Mouse Model of Sickle Cell Disease. Blood 2008;112: 2473.
9. Epping A, Newby RF, Panepinto JA, Brandow AM, Jirovec DL, Scott JP. Patterns of Academic Achievement in Children with Sickle Cell Disease. Pediatr Blood Cancer 2009;52:703-4.
10. Brandow AM and Panepinto JA. Evaluation of Children with Sickle Cell Disease Treated for Chronic or Recurrent Pain using a Multidimensional Pain Management Model. Pediatr Blood Cancer 2010;54:833.
11. Epping A, Jirovec DL, Newby RF, Panepinto JA, Brandow AM, Scott JP. Transitional Care: Educational and Employment Outcomes of Adults with Sickle Cell Disease. Pediatr Blood Cancer 2010;54:835.
12. Brandow AM, Kattappuram R, Panepinto JA. Hydroxyurea Effectively Decreases the Probability of Acute Chest Syndrome in Children with Sickle Cell Disease. Pediatr Blood Cancer 2010;56:949.
13. Brandow AM, Brousseau DC, Pajewski NM, Panepinto JA. Vaso-occlusive painful events in sickle cell disease: Impact on child well-being. Pediatric Blood & Cancer. 2011; 54: 92–97.