CURRICULUM VITAE
Antje Kroner-Milsch MD, PhD
Antje Kroner-Milsch MD, PhD
Associate Professor
Department of Neurosurgery
Division of Research
Department of Neurosurgery
Division of Research
OFFICE ADDRESS: |
VA Medical Center |
5000 W National Ave |
Milwaukee, WI 53295 |
EDUCATION: |
11/1995 - 06/2002 MD, Julius-Maximilians-University, Wuerzburg, Germany |
01/2004 - 08/2008 PhD, Julius-Maximilians-University, Wuerzburg, Germany |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
09/2008 - 07/2009 Postdoctoral Fellow, Neurology, Developmental Neurobiology, Julius-Maximilians-University, Wuerzburg, Germany |
08/2009 - 03/2014 Postdoctoral Fellow, Neurology, Centre for Research in Neuroscience, McGill University Health Centre, Montreal, QC |
04/2014 - 08/2015 Research Associate, Neurology, Centre for Research in Neuroscience, McGill University Health Centre, Montreal, QC |
FACULTY APPOINTMENTS: |
09/2015 - 06/2022 Assistant Professor, Neurosurgery, Research, Medical College of Wisconsin, VA Medical Center, 5000 W National Ave, Milwaukee, WI 53295 |
08/2016 - 06/2022 Assistant Professor (Secondary Appointment), Microbiology & Immunology, Medical College of Wisconsin, WI |
07/2022 - Present Associate Professor, Microbiology & Immunology, Medical College of Wisconsin, WI |
07/2022 - Present Associate Professor, Neurosurgery, Medical College of Wisconsin, VA Medical Center, 5000 W National Ave, Milwaukee, WI 53295 |
EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: |
01/2018 - 05/2022 Director (Seminar Course MMG 25300A), Microbiology & Immunology, Medical College of Wisconsin |
AWARDS AND HONORS: |
05/2004 - 04/2007 MD/ PhD Scholarship, University of Wuerzburg, Germany |
09/2005 Wyeth Young Investigator Award Multiple Sclerosis, Wyeth |
10/2007 Travel Grant, ECTRIMS |
05/2008 Chairs Fund Travel Grant, Gordon Research Conference Myelin |
02/2009 - 06/2009 Habilitation Scholarship, University of Wuerzburg, Germany |
08/2009 - 12/2009 Postdoctoral Fellowship, Canadian Institutes of Health Research (CIHR) Neuroinflammation Program |
01/2010 - 05/2010 Postdoctoral Fellowship Award, German Research Foundation (DFG) |
06/2010 - 03/2013 Postdoctoral Fellowship, Canadian Institutes of Health Research (CIHR) |
04/2013 - 03/2014 Postdoctoral Fellowship, Canadian Institutes of Health Research (CIHR) Neuroinflammation Program |
11/2013 Travel Grant, Canadian Institutes of Health Research (CIHR) Neuroinflammation Program |
11/2013 Travel Grant, Canadian Institutes of Health Research (CIHR) Neuroinflammation Program |
07/2016 Imagine More Award, Neuroscience Center, Medical College of Wisconsin |
11/2020 Outstanding Graduate School Educator, Medical College of Wisconsin |
10/2022 Faculty Service Award, Medical College of Wisconsin |
10/2022 Outstanding Committee Service Award, MCW |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
10/2009 - Present Society for Neuroscience (Member) |
01/2010 - Present German Association of Neuroscience (Member) |
01/2010 - 01/2020 Canadian Association of Neuroscience (Member) |
04/2016 - Present National Neurotrauma Society (Member) |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorship |
03/2018 - Present Frontiers in Molecular Neuroscience, Guest Associate Editor |
01/2019 - 01/2020 Frontiers Molecular Neuroscience, Topic Editor: Immune Cell Interactions with Target Cells |
06/2020 - Present Frontiers Cellular Neuroscience, Associate Editor: Non-Neuronal Cells |
08/2021 - Present Frontiers Cellular Neuroscience, Topic Editor: Schwann Cells |
Editorial Board |
04/01/2024 - Present Glial Health Research |
05/01/2024 - Present Glial Health Research |
Ad-Hoc Reviewer |
01/2010 - Present PlosOne |
02/2016 - Present Gene |
03/2016 - Present Journal of Neuroscience |
11/2016 - Present BMC Complementary and alternative medicine |
03/2017 - Present Journal of Neuroscience Research |
06/2017 - Present Molecular Cellular Neuroscience |
07/2017 - Present Free Radical Biology and Medicine |
09/2017 - Present Neurochemistry International |
11/2017 - Present Nature Neuroscience |
01/2018 - Present Journal of Neuroinflammation |
02/2018 - Present Brain, Behavior, and Immunity |
07/2018 - Present CNS Neuroscience & Therapeutics |
01/2019 - Present Acta Neuropathologica Communications |
09/2019 - Present Scientific reports |
09/2019 - Present Oxidative Medicine and Cellular Longevity |
12/2019 - Present Neuroscience Letters |
12/2019 - Present Immunopharmacology and Immunotoxicology |
02/2020 - Present International Journal of Molecular Sciences |
03/2020 - Present Experimental and Molecular Pathology |
05/2020 - Present Brain Research Bulletin |
08/2020 - Present Neuroscience |
08/2020 - Present Glia |
09/2020 - Present Developmental Neurobiology |
11/2020 - Present Experimental Neurology |
02/2021 - Present Behavioral Brain Research |
05/2021 - Present Frontiers in Pharmacology |
07/2021 - Present Journal of Neurotrauma |
08/2021 - Present Journal of Neurotrauma |
08/2021 - Present Journal of Neuroimmunology |
12/2021 - Present Journal of Advanced Research |
06/2022 - Present Advanced Therapeutics |
06/01/2023 - Present Journal of Inflammation Research |
10/01/2023 - Present Nature Communications |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
08/2019 - 10/2020 Reviewer, CTSI |
11/2020 - 11/2021 Member, Neuroscience Research Workgroup, MCW |
12/01/2020 - Present Vice Chair, IACUC, VA Medical Center |
09/22/2021 - Present Chair, Institutional Biosafety Committee, VAMC |
INTERNATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
01/2017 - Present Reviewer, Wings for Life- Spinal Cord Research Foundation, Salzburg, Austria |
09/2020 - Present Reviewer, Independent Scientific Merit Review Panel, New Jersey Commission on Spinal Cord Research |
01/01/2021 - Present Member, Editorial Board, ODC-SCI (Spinal cord injury database) |
07/2021 Reviewer, PSI Foundation, ON, Canada |
08/01/2021 - Present Member, Community Board, ODC-SCI (Spinal Cord Injury Database) |
10/2021 Early Career Reviewer, NIH Study Section Clinical Neuroimmunology and Brain Tumors (CNBT) |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
Local |
Kroner, A., Role of macrophages after spinal cord injury, Seminar, Marquette University, 05/10/2016 |
Kroner, A., Inflammatory response after spinal cord injury, Seminar, Department of Microbiology, MCW, 05/24/2016 |
Kroner, A., Secondary damage in SCI, Neuroscience Board, MCW, Milwaukee, 11/21/2017 |
Kroner, A., Secondary injury after SCI, SCI Center, Clement J. Zablocki VAMC, Milwaukee, 12/08/2017 |
Kroner, A., Secondary damage after SCI, Seminar, Department of Biochemistry, MCW, 10/17/2018 |
Kroner, A., Inflammation after SCI, Immunolunch, Center for Immunology, MCW, Milwaukee, 11/20/2018 |
Kroner, A., Role of CCL3 after SCI, Neuroinflammation Group, MCW, Milwaukee, 11/29/2018 |
Kroner, A., Inflammation and secondary damage after SCI, Grand Rounds, Neurosurgery, MCW, Milwaukee, 12/21/2018 |
Kroner, A., Inflammation and hemorrhage after spinal cord injury, Center for Immunology Annual Scientific Retreat, Center fro Immunology, MCW, 03/12/2020 |
Kroner, A., Hemorrhage after Spinal cord injury, Round Table Discussion, Center for Immunology, MCW, Milwaukee, 11/13/2020 |
Antje Kroner, Secondary Damage: Interplay between inflammation and hemorrhage after SCI, SCI seminar, Clement J Zablocki VAMC, Milwaukee, 07/31/2023 |
Kroner, Antje, Targeting hemorrhage mediated damage after Spinal Cord Injury, Immunology Research Roundtable, MCW, 11/28/2023 - Present |
Kroner, Antje, Neuroinflammation and SCI, Neuroinflammation Collaboration- NRC, Neuroscience Research Center, MCW, 12/14/2023 - Present |
International |
Kroner, A., Inflammation after Spinal cord injury, Seminar, University of Wuerzburg, Germany, 05/02/2016 |
Kroner, A., Role of macrophage inflammatory protein (MIP)-1alpha (CCL3) and its receptors after spinal cord injury (SCI) and its influence on secondary damage, Wings for Life Annual Meeting, Salzburg, Austria, 05/11/2017 - 05/12/2017 |
Kroner, A., Targeting inflammation to reduce secondary damage after SCI, International Symposium on Neural Regeneration, Asilomar, Pacific Grove, CA, 11/27/2017 - 11/30/2017 |
Kroner, A., Role of macrophage inflammatory protein (MIP)-1alpha (CCL3) and its receptors after spinal cord injury (SCI) and its influence on secondary damage, Wings for Life Annual Meeting, Salzburg, Austria, 04/23/2018 - 04/25/2018 |
Pelisch, N., Stehlik, K., Aperi, A., Rosas, J., Kroner, A., Role of macrophage inflammatory protein (MIP)-1alpha (CCL3) and its receptors after spinal cord injury (SCI) and its influence on secondary damage, Wings for Life Annual Meeting, Salzburg, Austria, 05/08/2019 - 05/10/2019 |
Kroner, A, Inflammation after Spinal Cord Injury, International Online SCI Research Seminars (IOSCIRS), virtual, 12/15/2020 |
Antje Kroner, Neuroinflammation n the injured spinal cord, Symposium: Inflammation and Neurological Disorders, Wuerzburg, Germany, 10/15/2022 |
S. Kafura, A. Bachmann, J. Page K. Satkunendrarajah and A. Kroner, Role of heme binding proteins after spinal cord injury, Wings for Life Scientific Meeting, Salzburg, Austria, 05/16/2023 - 05/17/2023 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
Local |
Kroner, A., Modulating Inflammation and Secondary Damage in a Mouse Model of Spinal Cord Injury By Targeting IL-12 and IL-23, From Community to Battlefield, MCW, Milwaukee, 12/07/2017 |
National |
Kroner, A., Aperi, B., Stehlik, K., David S., Expression and role of pro-inflammatory cytokines IL-12 and, National Neurotrauma Society, Annual Meeting, Lexington, KY, 06/26/2016 - 06/29/2016 |
Kroner, A., Expression and role of the pro-inflammatory chemokine CCL3 and its receptors after spinal cord injury (SCI) and its influence on secondary damage, National Neurotrauma Society, Snowbird, UT, 07/08/2017 - 07/12/2017 |
Pelisch, N., Kroner, A., Macrophage inflammatory protein-1alpha (CCL3) and its receptors contribute to secondary damage following spinal cord injury, National Neurotrauma Society, Philadelphia, PA, 06/30/2019 - 07/03/2019 |
Kishan Patel, Nicolas Pelisch, Antje Kroner, Role of hemopexin in secondary damage after spinal cord injury, Global Neurosurgery Conference, virtual, 09/11/2020 |
International |
Kroner A., Noguiera Santos E., Lopez-Vales R, David S., MK2 contributes to regeneration after peripheral nerve injury., Society of Neuroscience, Annual Meeting, Chicago, IL, 10/17/2015 - 10/21/2015 |
Kroner A., Aperi, B., Stehlik, K., David S., Expression and role of IL-12 and IL-23 in spinal cord injury, Society for Neuroscience Annual Meeting, San Diego, CA, 11/12/2016 - 11/16/2016 |
Zarruk, J.G., Noguiera Santos E., Kroner A., David S., Transplantation of bone marrow‐derived, endMS conference, Toronto, ON, Canada, 12/06/2016 - 12/09/2016 |
Kroner, A., Role and expression of CCL3 and its receptors after spinal cord injury, Society for Neuroscience, Washington, DC, 11/11/2017 - 11/15/2017 |
Kroner, A., MIP-1alpha (CCL3): A role in spinal cord injury (SCI) and secondary damage, National and International Neurotrauma Society Meeting, Toronto, ON Canada, 08/13/2018 - 08/16/2018 |
Kroner, A., Role of IL-12, IL-23 and their receptors after spinal cord injury (SCI) and their impact on secondary damage, Society for Neuroscience, San Diego, CA, 11/03/2018 - 11/07/2018 |
Rosas, J., Pelisch, N., Stehlik, K., Aperi, B., Swartz, K., Kroner, A., The pro-inflammatory cytokine IL-12 impairs recovery after spinal cord injury., Gordon Research Conference, Waterville Valley, NH, 06/17/2019 |
Jose Rosas, Nicolas Pelisch, Brandy Aperi, Kyle Stehlik, Karin Swartz, Antje Kroner, Absence of IL-12p40 mediates a beneficial effect on recovery after spinal cord injury., Society for Neuroscience Annual Meeting, Chicago, 10/19/2019 - 10/22/2019 |
Nicolas Pelisch, Kyle Stehlik, Brandy Aperi, Antje Kroner1, Role of Macrophage inflammatory protein-1alpha (CCL3) in secondary damage following contusive spinal cord injury, Society for Neuroscience Annual Meeting, Chicago, 10/19/2019 - 10/22/2019 |
Nicolas Pelisch, Kishan Patel, Antje Kroner, Role of hemorrhage and impact of heme-binding proteins after spinal cord injury, ISNR Conference, Asilomar, CA, 01/26/2020 - 01/30/2020 |
Dan Reinhardt, Christina Dolick, Dante Graham, Kyle Stehlik, Antje Kroner, Kajana Satkunendrarajah, Nimodipine prevents spasticity and promotes motor recovery after spinal cord injury, Proceedings of Technological Advances in Science, Medicine and Engineering Conference 2021 (Tasme), virtual, 07/03/2021 - 07/04/2021 |
Antje Kroner, Nicolas Pelisch, Jose Rosas, Role of chemokine messaging after Spinal Cord Injury, Proceedings of Technological Advances in Science, Medicine and Engineering Conference 2021 (TASME), Virtual, 07/03/2021 - 07/04/2021 |
Jose Rosas, Nicolas Pelisch, Brandy Aperi, Kyle Stehlik, Matt Budde, Karin Swartz, Antje Kroner, IL-12p40 contributes to secondary damage and functional impairment after spinal cord injury, Proceedings of Technological Advances in Science, Medicine and Engineering Conference 2021 (Tasme), virtual, 07/03/2021 - 07/04/2021 |
Nicolas Pelisch, Jose Rosas, Kyle Stehlik, Brandy Aperi, Antje Kroner, Role of the heme-binding protein Hemopexin following spinal cord injury, Proceedings of Technological Advances in Science, Medicine and Engineering Conference 2021 (TASME), virtual, 07/03/2021 - 07/04/2021 |
Justin Page, Jose Rosas Almanza, Brandy Aperi, Kyle Stehlik, Antje Kroner, The functional role and therapeutic potential of heme binding proteins after cervical SCI, Society For Neuroscience, San Diego, CA, 11/12/2022 - 11/15/2022 |
Justin Page, Shannon Kafura, Alexandra Bachmann, Jose Rosas Almanza, Kajana Satkunendrarajah & Antje Kroner, The functional role and therapeutic potential of heme binding proteins after cervical SCI, International Symposium on Neural Regeneration, Stevenson, WA, 04/24/2023 - 04/27/2023 |
Alexandra Bachmann, Justin Page, Kajana Satkunendrarajah, Antje Kroner, CCR5 inhibition using maraviroc after spinal cord injury, Central Nervous System Injury and Repair
Gordon Research Conference, Lucca, Italy, 07/09/2023 - 07/14/2023 |
Alexandra Bachmann, Justin Page, Anthony Raimondi, Shannon Kafura, Emma Tabor, Antje Kroner, Inhibition of CCR5 improves functional recovery and reduces secondary tissue damage after thoracic SCI, Society for Neuroscience, Washington DC, 11/11/2023 - 11/15/2023 |
H. SWEETMAN, D. GRAHAM, A. KRONER, S. GOSGNACH, C. M. OLSEN, K. SATKUNENDRARAJAH, PSTR341.09 / Z22 - Sensory cortical control of locomotion after spinal cord injury, Society for Neuroscience, Washington DC, 11/11/2023 - 11/15/2023 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
07/04/2016 - Present Member, Research Affairs Committee, MCW |
11/01/2016 - Present Member, Equipment Committee, VA Medical Center |
11/26/2018 - 05/30/2020 Member, Search Committee, Neuroscience Research Center, MCW |
12/01/2022 - Present Member, Search Committee, Center for Immunology, MCW |
Hospital |
02/02/2016 - Present Scientific Member, IACUC, VA Medical Center |
MEDICAL COLLEGE TEACHING ACTIVITIES: |
Graduate Student Education |
01/01/2018 - Present Course Director: Seminar Course |
01/25/2021 - Present Instructor: Foundations in Biomedical Sciences IV |
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Graduate Students |
PhD Committees |
Daniel Fehrenbach, Medical College of Wisconsin, 01/18/2018 - 11/22/2020 CD14 and the Macrophage in Salt-Sensitive Hypertension and Renal Injury, Graduation |
Seung Yi Lee, MCW, 09/01/2019 - 04/15/2022 From Characterization to Treatment of
Cervical Spinal Cord Injury in Rat Models Using
Multimodal Magnetic Resonance Imaging, Graduation |
PhD Students Advised |
Jose Rosas, Medical College of Wisconsin, 02/01/2018 - 12/15/2022 IL-12 Promotes Secondary Damage and Locomotor Impairment in Spinal Cord Injury., Graduation |
Postdoctoral Students |
Nicolas Pelisch, MCW, 02/2019 - 10/2021 Supervising PI |
EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED: |
High School Students |
Athena Kafkas, SUPREMES Program, 02/01/2020 - 08/01/2021 Supervising PI |
Undergraduate Students |
Rebecca Kolbeck, MCW, VA Neuroscience Labs, 06/05/2017 - 08/15/2017 Supervising PI |
Morgan Weaver, MCW, VA Neuroscience Labs, 06/09/2017 - 07/17/2017 Supervising PI |
Edward O'Reilly, MCW/ Marquette, 09/01/2017 - 12/21/2017 Supervising PI |
Nicholas Schneider, MCW/ Marquette, 09/01/2017 - 12/21/2017 Supervising PI |
COMMUNITY SERVICE ACTIVITIES: |
05/06/2018 Organizer for local "Wings for Life World Run" Fundraiser |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. David S, Jhelum P, Ryan F, Jeong SY, Kroner A. Dysregulation of Iron Homeostasis in the Central Nervous System and the Role of Ferroptosis in Neurodegenerative Disorders. Antioxid Redox Signal. 2022 Jul;37(1-3):150-170. |
2. Pelisch N, Rosas Almanza J, Stehlik KE, Aperi BV, Kroner A. Use of a Self-Delivering Anti-CCL3 FANA Oligonucleotide as an Innovative Approach to Target Inflammation after Spinal Cord Injury. eNeuro. 2021;8(2). PMCID: PMC7986543 |
3. Pelisch N, Rosas Almanza J, Stehlik KE, Aperi BV, Kroner A. CCL3 contributes to secondary damage after spinal cord injury. J Neuroinflammation. 2020 Nov 27;17(1):362. PMCID: PMC7694914 |
4. Reinhardt DR, Stehlik KE, Satkunendrarajah K, Kroner A. Bilateral cervical contusion spinal cord injury: A mouse model to evaluate sensorimotor function. Exp Neurol. 2020 Sep;331:113381. |
5. Kroner A, Rosas Almanza J. Role of microglia in spinal cord injury. Neurosci Lett. 2019 Sep 14;709:134370. |
6. David S, Kroner A, Greenhalgh AD, Zarruk JG, López-Vales R. Myeloid cell responses after spinal cord injury. J Neuroimmunol. 2018 Aug 15;321:97-108. |
7. Kaplan A, Morquette B, Kroner A, Leong S, Madwar C, Sanz R, Banerjee SL, Antel J, Bisson N, David S, Fournier AE. Small-Molecule Stabilization of 14-3-3 Protein-Protein Interactions Stimulates Axon Regeneration. Neuron. 2017 Mar 08;93(5):1082-1093.e5. |
8. Greenhalgh AD, Passos Dos Santos R, Zarruk JG, Salmon CK, Kroner A, David S. Arginase-1 is expressed exclusively by infiltrating myeloid cells in CNS injury and disease. Brain Behav Immun. 2016 Aug;56:61-7. |
9. Sadovnick AD, Traboulsee AL, Bernales CQ, Ross JP, Forwell AL, Yee IM, Guillot-Noel L, Fontaine B, Cournu-Rebeix I, Alcina A, Fedetz M, Izquierdo G, Matesanz F, Hilven K, Dubois B, Goris A, Astobiza I, Alloza I, Antigüedad A, Vandenbroeck K, Akkad DA, Aktas O, Blaschke P, Buttmann M, Chan A, Epplen JT, Gerdes LA, Kroner A, Kubisch C, Kümpfel T, Lohse P, Rieckmann P, Zettl UK, Zipp F, Bertram L, Lill CM, Fernandez O, Urbaneja P, Leyva L, Alvarez-Cermeño JC, Arroyo R, Garagorri AM, García-Martínez A, Villar LM, Urcelay E, Malhotra S, Montalban X, Comabella M, Berger T, Fazekas F, Reindl M, Schmied MC, Zimprich A, Vilariño-Güell C. Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients. G3 (Bethesda). 2016 Jul 07;6(7):2073-9. PMCID: PMC4938660 |
10. Lill CM, Luessi F, Alcina A, Sokolova EA, Ugidos N, de la Hera B, Guillot-Noël L, Malhotra S, Reinthaler E, Schjeide BM, Mescheriakova JY, Mashychev A, Wohlers I, Akkad DA, Aktas O, Alloza I, Antigüedad A, Arroyo R, Astobiza I, Blaschke P, Boyko AN, Buttmann M, Chan A, Dörner T, Epplen JT, Favorova OO, Fedetz M, Fernández O, García-Martínez A, Gerdes LA, Graetz C, Hartung HP, Hoffjan S, Izquierdo G, Korobko DS, Kroner A, Kubisch C, Kümpfel T, Leyva L, Lohse P, Malkova NA, Montalban X, Popova EV, Rieckmann P, Rozhdestvenskii AS, Schmied C, Smagina IV, Tsareva EY, Winkelmann A, Zettl UK, Binder H, Cournu-Rebeix I, Hintzen R, Zimprich A, Comabella M, Fontaine B, Urcelay E, Vandenbroeck K, Filipenko M, Matesanz F, Zipp F, Bertram L. Genome-wide significant association with seven novel multiple sclerosis risk loci. J Med Genet. 2015 Dec;52(12):848-55. |
11. Schrewe L, Lill CM, Liu T, Salmen A, Gerdes LA, Guillot-Noel L, Akkad DA, Blaschke P, Graetz C, Hoffjan S, Kroner A, Demir S, Böhme A, Rieckmann P, ElAli A, Hagemann N, Hermann DM, Cournu-Rebeix I, Zipp F, Kümpfel T, Buttmann M, Zettl UK, Fontaine B, Bertram L, Gold R, Chan A. Investigation of sex-specific effects of apolipoprotein E on severity of EAE and MS. J Neuroinflammation. 2015 Dec 16;12:234. PMCID: PMC4681148 |
12. Siqueira Mietto B, Kroner A, Girolami EI, Santos-Nogueira E, Zhang J, David S. Role of IL-10 in Resolution of Inflammation and Functional Recovery after Peripheral Nerve Injury. J Neurosci. 2015 Dec 16;35(50):16431-42. PMCID: PMC6605511 |
13. David S, Greenhalgh AD, Kroner A. Macrophage and microglial plasticity in the injured spinal cord. Neuroscience. 2015 Oct 29;307:311-8. |
14. Zarruk JG, Berard JL, Passos dos Santos R, Kroner A, Lee J, Arosio P, David S. Expression of iron homeostasis proteins in the spinal cord in experimental autoimmune encephalomyelitis and their implications for iron accumulation. Neurobiol Dis. 2015 Sep;81:93-107. |
15. Kroner A, Greenhalgh AD, Zarruk JG, Passos Dos Santos R, Gaestel M, David S. TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord. Neuron. 2014 Sep 03;83(5):1098-116. |
16. Lill CM, Schilling M, Ansaloni S, Schröder J, Jaedicke M, Luessi F, Schjeide BM, Mashychev A, Graetz C, Akkad DA, Gerdes LA, Kroner A, Blaschke P, Hoffjan S, Winkelmann A, Dörner T, Rieckmann P, Steinhagen-Thiessen E, Lindenberger U, Chan A, Hartung HP, Aktas O, Lohse P, Buttmann M, Kümpfel T, Kubisch C, Zettl UK, Epplen JT, Zipp F, Bertram L. Assessment of microRNA-related SNP effects in the 3' untranslated region of the IL22RA2 risk locus in multiple sclerosis. Neurogenetics. 2014 May;15(2):129-34. |
17. International Multiple Sclerosis Genetics Consortium, Lill CM, Schjeide BM, Graetz C, Ban M, Alcina A, Ortiz MA, Pérez J, Damotte V, Booth D, Lopez de Lapuente A, Broer L, Schilling M, Akkad DA, Aktas O, Alloza I, Antigüedad A, Arroyo R, Blaschke P, Buttmann M, Chan A, Compston A, Cournu-Rebeix I, Dörner T, Epplen JT, Fernández Ó, Gerdes LA, Guillot-Noël L, Hartung HP, Hoffjan S, Izquierdo G, Kemppinen A, Kroner A, Kubisch C, Kümpfel T, Li SC, Lindenberger U, Lohse P, Lubetzki C, Luessi F, Malhotra S, Mescheriakova J, Montalban X, Papeix C, Paredes LF, Rieckmann P, Steinhagen-Thiessen E, Winkelmann A, Zettl UK, Hintzen R, Vandenbroeck K, Stewart G, Fontaine B, Comabella M, Urcelay E, Matesanz F, Sawcer S, Bertram L, Zipp F. MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis. Brain. 2013 Jun;136(Pt 6):1778-82. PMCID: PMC3673463 |
18. Ip CW, Kroner A, Groh J, Huber M, Klein D, Spahn I, Diem R, Williams SK, Nave KA, Edgar JM, Martini R. Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse. PLoS One. 2012;7(8):e42554. PMCID: PMC3414455 |
19. Schulz K, Kroner A, David S. Iron efflux from astrocytes plays a role in remyelination. J Neurosci. 2012 Apr 04;32(14):4841-7. PMCID: PMC6620916 |
20. David S, Kroner A. Repertoire of microglial and macrophage responses after spinal cord injury. Nat Rev Neurosci. 2011 Jun 15;12(7):388-99. |
21. Nischwitz S, Cepok S, Kroner A, Wolf C, Knop M, Müller-Sarnowski F, Pfister H, Rieckmann P, Hemmer B, Ising M, Uhr M, Bettecken T, Holsboer F, Müller-Myhsok B, Weber F. More CLEC16A gene variants associated with multiple sclerosis. Acta Neurol Scand. 2011 Jun;123(6):400-6. |
22. Nischwitz S, Cepok S, Kroner A, Wolf C, Knop M, Müller-Sarnowski F, Pfister H, Roeske D, Rieckmann P, Hemmer B, Ising M, Uhr M, Bettecken T, Holsboer F, Müller-Myhsok B, Weber F. Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis. J Neuroimmunol. 2010 Oct 08;227(1-2):162-6. |
23. Kohl B, Groh J, Wessig C, Wiendl H, Kroner A, Martini R. Lack of evidence for a pathogenic role of T-lymphocytes in an animal model for Charcot-Marie-Tooth disease 1A. Neurobiol Dis. 2010 Apr;38(1):78-84. |
24. Kroner A, Ip CW, Thalhammer J, Nave KA, Martini R. Ectopic T-cell specificity and absence of perforin and granzyme B alleviate neural damage in oligodendrocyte mutant mice. Am J Pathol. 2010 Feb;176(2):549-55. PMCID: PMC2808063 |
25. Kroner A, Schwab N, Ip CW, Ortler S, Göbel K, Nave KA, Mäurer M, Martini R, Wiendl H. Accelerated course of experimental autoimmune encephalomyelitis in PD-1-deficient central nervous system myelin mutants. Am J Pathol. 2009 Jun;174(6):2290-9. PMCID: PMC2684193 |
26. Kroner A, Schwab N, Ip CW, Leder C, Nave KA, Mäurer M, Wiendl H, Martini R. PD-1 regulates neural damage in oligodendroglia-induced inflammation. PLoS One. 2009;4(2):e4405. PMCID: PMC2635015 |
27. Ip CW, Kroner A, Kohl B, Wessig C, Martini R. Tacrolimus (FK506) causes disease aggravation in models for inherited peripheral myelinopathies. Neurobiol Dis. 2009 Feb;33(2):207-12. |
28. Buttmann M, Nowak E, Kroner A, Hemmer B, Lesch KP, Rieckmann P. Analysis of the stathmin rs182455 single nucleotide promoter polymorphism in patients with multiple sclerosis. J Neurogenet. 2008;22(3):181-6. |
29. Kroner A, Schwab N, Ip CW, Sommer C, Wessig C, Wiendl H, Martini R. The co-inhibitory molecule PD-1 modulates disease severity in a model for an inherited, demyelinating neuropathy. Neurobiol Dis. 2009 Jan;33(1):96-103. |
30. International Multiple Sclerosis Genetics Consortium (IMSGC). Refining genetic associations in multiple sclerosis. Lancet Neurol. 2008 Jul;7(7):567-9. PMCID: PMC2696028 |
31. Ip CW, Kohl B, Kleinschnitz C, Reuss B, Nave KA, Kroner A, Martini R. Origin of CD11b+ macrophage-like cells in the CNS of PLP-overexpressing mice: low influx of haematogenous macrophages and unchanged blood-brain-barrier in the optic nerve. Mol Cell Neurosci. 2008 Aug;38(4):489-94. |
32. Ortler S, Leder C, Mittelbronn M, Zozulya AL, Knolle PA, Chen L, Kroner A, Wiendl H. B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis. Eur J Immunol. 2008 Jun;38(6):1734-44. |
33. Weber F, Fontaine B, Cournu-Rebeix I, Kroner A, Knop M, Lutz S, Müller-Sarnowski F, Uhr M, Bettecken T, Kohli M, Ripke S, Ising M, Rieckmann P, Brassat D, Semana G, Babron MC, Mrejen S, Gout C, Lyon-Caen O, Yaouanq J, Edan G, Clanet M, Holsboer F, Clerget-Darpoux F, Müller-Myhsok B. IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations. Genes Immun. 2008 Apr;9(3):259-63. |
34. Yu X, Koczan D, Sulonen AM, Akkad DA, Kroner A, Comabella M, Costa G, Corongiu D, Goertsches R, Camina-Tato M, Thiesen HJ, Nyland HI, Mørk SJ, Montalban X, Rieckmann P, Marrosu MG, Myhr KM, Epplen JT, Saarela J, Ibrahim SM. mtDNA nt13708A variant increases the risk of multiple sclerosis. PLoS One. 2008 Feb 13;3(2):e1530. PMCID: PMC2217590 |
35. Leder C, Schwab N, Ip CW, Kroner A, Nave KA, Dornmair K, Martini R, Wiendl H. Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice. Mol Cell Neurosci. 2007 Nov;36(3):416-24. |
36. Kroner A, Grimm A, Johannssen K, Mäurer M, Wiendl H. The genetic influence of the nonclassical MHC molecule HLA-G on multiple sclerosis. Hum Immunol. 2007 May;68(5):422-5. |
37. Ey B, Kobsar I, Blazyca H, Kroner A, Martini R. Visualization of degenerating axons in a dysmyelinating mouse mutant with axonal loss. Mol Cell Neurosci. 2007 May;35(1):153-60. |
38. Ip CW, Kroner A, Crocker PR, Nave KA, Martini R. Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice. Neurobiol Dis. 2007 Jan;25(1):105-11. |
39. Buck D, Kroner A, Rieckmann P, Mäurer M, Wiendl H. Analysis of the C/T(-1) single nucleotide polymorphism in the CD40 gene in multiple sclerosis. Tissue Antigens. 2006 Oct;68(4):335-8. |
40. Gronen F, Ruprecht K, Weissbrich B, Klinker E, Kroner A, Hofstetter HH, Rieckmann P. Frequency analysis of HLA-B7-restricted Epstein-Barr virus-specific cytotoxic T lymphocytes in patients with multiple sclerosis and healthy controls. J Neuroimmunol. 2006 Nov;180(1-2):185-92. |
41. Ip CW, Kroner A, Bendszus M, Leder C, Kobsar I, Fischer S, Wiendl H, Nave KA, Martini R. Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes. J Neurosci. 2006 Aug 02;26(31):8206-16. PMCID: PMC6673777 |
42. Salih HR, Wintterle S, Krusch M, Kroner A, Huang YH, Chen L, Wiendl H. The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans. Exp Hematol. 2006 Jul;34(7):888-94. |
43. Wang Ip C, Kroner A, Fischer S, Berghoff M, Kobsar I, Mäurer M, Martini R. Role of immune cells in animal models for inherited peripheral neuropathies. Neuromolecular Med. 2006;8(1-2):175-90. |
44. Linker RA, Kroner A, Horn T, Gold R, Mäurer M, Bendszus M. Iron particle-enhanced visualization of inflammatory central nervous system lesions by high resolution: preliminary data in an animal model. AJNR Am J Neuroradiol. 2006;27(6):1225-9. PMCID: PMC8133929 |
45. Kobsar I, Oetke C, Kroner A, Wessig C, Crocker P, Martini R. Attenuated demyelination in the absence of the macrophage-restricted adhesion molecule sialoadhesin (Siglec-1) in mice heterozygously deficient in P0. Mol Cell Neurosci. 2006 Apr;31(4):685-91. |
46. Zavala-Góngora R, Kroner A, Bernthaler P, Knaus P, Brehm K. A member of the transforming growth factor-beta receptor family from Echinococcus multilocularis is activated by human bone morphogenetic protein 2. Mol Biochem Parasitol. 2006 Apr;146(2):265-71. |
47. Vogler S, Goedde R, Miterski B, Gold R, Kroner A, Koczan D, Zettl UK, Rieckmann P, Epplen JT, Ibrahim SM. Association of a common polymorphism in the promoter of UCP2 with susceptibility to multiple sclerosis. J Mol Med (Berl). 2005 Oct;83(10):806-11. |
48. Kroner A, Vogel F, Kolb-Mäurer A, Kruse N, Toyka KV, Hemmer B, Rieckmann P, Mäurer M. Impact of the Asp299Gly polymorphism in the toll-like receptor 4 (tlr-4) gene on disease course of multiple sclerosis. J Neuroimmunol. 2005 Aug;165(1-2):161-5. |
49. Kroner A, Mehling M, Hemmer B, Rieckmann P, Toyka KV, Mäurer M, Wiendl H. A PD-1 polymorphism is associated with disease progression in multiple sclerosis. Ann Neurol. 2005 Jul;58(1):50-7. |
50. Rosche B, Cepok S, Stei S, Vogel F, Grummel V, Hoffmann S, Kroner A, Mäurer M, Rieckmann P, Sommer N, Hemmer B. The role of the polio virus receptor and the herpesvirus entry mediator B genes for the development of MS. J Neuroimmunol. 2004 Nov;156(1-2):171-7. |
51. Kroner A, Mäurer M, Loserth S, Kleinschnitz C, Hemmer B, Rosche B, Toyka KV, Rieckmann P. Analysis of the monocyte chemoattractant protein 1 -2518 promoter polymorphism in patients with multiple sclerosis. Tissue Antigens. 2004 Jul;64(1):70-3. |
52. Spiliotis M, Kroner A, Brehm K. Identification, molecular characterization and expression of the gene encoding the epidermal growth factor receptor orthologue from the fox-tapeworm Echinococcus multilocularis. Gene. 2003 Dec 24;323:57-65. |
53. Zavala-Góngora R, Kroner A, Wittek B, Knaus P, Brehm K. Identification and characterisation of two distinct Smad proteins from the fox-tapeworm Echinococcus multilocularis. Int J Parasitol. 2003 Dec;33(14):1665-77. |
54. Brehm K, Wolf M, Beland H, Kroner A, Frosch M. Analysis of differential gene expression in Echinococcus multilocularis larval stages by means of spliced leader differential display. Int J Parasitol. 2003 Sep 30;33(11):1145-59. |
55. Konrad C, Kroner A, Spiliotis M, Zavala-Góngora R, Brehm K. Identification and molecular characterisation of a gene encoding a member of the insulin receptor family in Echinococcus multilocularis. Int J Parasitol. 2003 Mar;33(3):301-12. |
56. David S, Ryan F, Jhelum P, Kroner A. Ferroptosis in Neurological Disease. Neuroscientist. 2023 Oct;29(5):591-615. |
57. Rosas Almanza J, Stehlik KE, Page JJ, Xiong SH, Tabor EG, Aperi B, Patel K, Kodali R, Kurpad S, Budde MD, Tarima S, Swartz K, Kroner A. IL-12p40 promotes secondary damage and functional impairment after spinal cord contusional injury. J Neurosci Res. 2022 Dec;100(12):2213-2231. |
58. Page JJ, Almanza JR, Xiong S, Aishwarya V, Kroner A. Self-delivering mRNA inhibitors of MK2 improve outcomes after spinal cord injury. J Neuroimmunol. 2023 Jun 15;379:578103. |
59. St-Pierre MK, González Ibáñez F, Kroner A, Tremblay MÈ. Microglia/macrophages are ultrastructurally altered by their proximity to spinal cord injury in adult female mice. J Neuroinflammation. 2023 Nov 21;20(1):273. PMCID: PMC10664529 |
