Faculty Collaboration Database -

CURRICULUM VITAE

Cara Lynn Mack MD

Chief, Professor
Department of Pediatrics
Division of Gastroenterology


OFFICE ADDRESS:
Children's Corporate Center
999 N 92 St
Milwaukee, WI 53226
Phone: 414-266-3872
Fax: 414-266-3676
Email: cmack@mcw.edu


EDUCATION:
1982 - 1986 BS, University of Wisconsin, Madison
1988 - 1992 MD, Loyola University Chicago, Stritch School of Medicine


POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
1992 - 1993 Internship, Pediatrics, University of Chicago Hospitals, Chicago, Illinois
1993 - 1995 Residency, Pediatrics, University of Chicago Hospitals, Chicago, Illinois
1995 - 1996 Chief Resident, Pediatrics, University of Chicago Hospitals, Chicago, Illinois
1998 - 2001 Fellowship, Pediatric Gastroenterology, Hepatology & Nutrition Children's Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, Illinois


FACULTY APPOINTMENTS:
2001 - 2002 Instructor, Department of Pediatrics, Division of Pediatric Gastroenterology and Hepatology, Children's Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, IL
2002 - 2008 Assistant Professor, Department of Pediatrics, Pediatric Gastroenterology, Hepatology & Nutrition, University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, CO
2003 - 2022 Assistant Professor (secondary appointment), Department of Medicine, Division of Allergy and Clinical Immunology, University of Colorado School of Medicine, Aurora, CO
2008 - 2016 Associate Professor, Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology & Nutrition, University of Colorado School of Medicine, Aurora, CO
2016 - 2022 Professor, Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology & Nutrition, University of Colorado School of Medicine, Aurora, CO
2018 - 2022 Tenured Professor & Hewit/Andrews Chair in Pediatric Liver Disease, Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology & Nutrition, University of Colorado School of Medicine, Aurora, CO
2022 - Present Professor and Division Chief, Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology & Nutrition, Medical College of Wisconsin, Children's Wisconsin, Milwaukee, WI


ADMINISTRATIVE APPOINTMENTS:
2009 - 2022 Member, Pediatric Indirect Costs Request Committee, University of Colorado School of Medicine
2012 - 2016 Member, Department of Pediatrics Promotions Midpoint Review Committee, University of Colorado School of Medicine
2015 - 2016 Member, Department of Pediatrics Promotions Committee, University of Colorado School of Medicine
2016 - 2022 Co-Chair, Department of Pediatrics Midpoint Promotions Review Committee, University of Colorado School of Medicine


EDUCATIONAL ADMINISTRATIVE APPOINTMENTS:
2012 - 2013 Associate Director- Fellowship Training Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, CHCO, University of Colorado School of Medicine
2013 - 2022 Director- Fellowship Training Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, CHCO, University of Colorado School of Medicine


HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:
2017 - 2022 Medical Director- Pediatric Liver Center, Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology & Nutrition, University of Colorado School of Medicine, Aurora, CO
2022 - Present Division Chief, Pediatrics, Division of Pediatric Gastroenterology, Hepatology & Nutrition, Medical College of Wisconsin, Milwaukee, WI


RESEARCH ADMINISTRATIVE APPOINTMENTS:
1986 - 1987 Laboratory Research Technician, University of Chicago, Chicago, IL
1987 - 1988 Laboratory Research Supervisor, Pathology, Michael Reese Hospital, Chicago, IL
2002 - 2022 Mack Laboratory PI/ Supervisor, Pediatrics, Pediatric Gastroenterology, Hepatology & Nutrition, University of Colorado School of Medicine, Aurora, CO
2013 - 2018 Member, Department of Pediatrics Research Institute Grant Review, University of Colorado School of Medicine
2016 - 2022 Director of GALIIP Pilot Awards, University of CO Gastrointestinal and Liver Innate Immune Program (GALIIP), University of Colorado School of Medicine, Aurora, CO


HOSPITAL STAFF PRIVILEGES:
1996 - 1998 Medical Staff Physician, General Pediatrics- Department of Pediatrics, Holy Cross Hospital, Chicago, Illinois
2001 - 2002 Instructor- Department of Pediatrics, Division of Gastroenterology and Hepatology, Children's Memorial Hospital, Chicago, Illinois
2002 - 2022 Attending Physician- Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology & Nutrition, CHCO and University of Colorado School of Medicine, Aurora, Colorado
2022 - Present Attending Physician- Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology & Nutrition, Children's Wisconsin, Medical College of Wisconsin, Milwaukee, WI


SPECIALTY BOARDS AND CERTIFICATION:


Board Certified	Issue Date	Expiration
American Board of Pediatrics	1995	2012
ABP- Gastroenterology	2005	2025
ABP- Transplant Hepatology	2006	2026


Licensure	Number	Issue Date	Expiration
Colorado License	DR-040900	2002	2023
Wisconsin Medical License	76745-20	2022	10/2023


AWARDS AND HONORS:
1983 Phi Eta Sigma, Freshman Honor Society
1986 Molecular Biology Degree, Honors Candidate
1989 Diabetes Young Investigator Award- Loyola University Stritch School of Medicine
1990 - 1992 Illinois Department of Public Health Scholarship
1999 Johnny Jenna Liver Scholar Award, Jenna Foundation
2005 March of Dimes Basil O'Connor Starter Scholar Research Award
2005 American Association for the Study of Liver Disease (AASLD), Pediatric Research Abstract Award, San Francisco, CA
2009 - 2015 Best Doctors in America
2013 Teacher of the Year, Fellowship Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital Colorado
2016 - 2020 Patient-Family Experience Excellence in Patient Care Award, CHCO (top 1% 2019; top 10-20% 2016, 2018, 2020), Children's Hospital Colorado
2017 - Present Fellow, AASLD
2018 - 2022 Tenure, University of Colorado School of Medicine
2018 - 2022 Hewit/Andrews Chair in Pediatric Liver Disease
2020 - Present Fellow, North American Society of Pediatric Gastroenterology, Hepatology & Nutrition (NASPGHAN)


MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
1995 - 2001 American Association of Pediatrics
1998 - Present American Association for the Study of Liver Disease (AASLD)
1999 - Present North American Society for Pediatric Gastroenterology (Hepatology and Nutrition (NASPGHAN))
2006 - 2018 Society for Pediatric Research (SPR)


EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Editorship
2003 - 2006 Co-editor: Journal of Pediatric Gastroenterology and Nutrition
2016 - 2021 Associate Editor: Hepatology
2019 - Present Editor, Liver Disease in Children, 5th Edition, Lippincott Williams & Wilkins, Cambridge University Press, PA. (eds: Suchy FJ, Sokol RJ, Balistreri WF, Shneider B, Mack CL and Bezerra J)
09/2021 - Present Editor, The Association of Pediatric Gastroenterology & Nutrition Nurses (APGNN), Introduction to Pediatric Liver Disease Module, APGNN Assessment-based Certificate Accreditation Program
Editorial Board
2014 - 2018 Editorial Board Member: Cellular and Molecular Gastroenterology and Hepatology
Journal Review
2004 - Present Reviewer for following journals: Gastroenterology; Hepatology; Journal of Pediatric Gastroenterology, Hepatology and Nutrition; Pediatric Research; Journal of Pediatrics; Pediatrics; Journal of Hepato
2004 Abstract reviewer for pediatric hepatology abstracts, World Congress on Pediatric Gastroenterology, Hepatology and Nutrition, Paris, France
2005 - Present Abstract reviewer for Digestive Diseases Weekly Annual Meeting- Pediatrics Section
2005 - 2008 Abstract reviewer for NASPGHAN Annual Meetings
2010 - 2014 Abstract reviewer for AASLD Annual Meetings
2018 - 2020 Abstract reviewer for NASPGHAN Annual Meetings


LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2005 - 2013 Member, Medical School Admissions Committee, University of Colorado School of Medicine
2006 - 2022 Member, Scholarship Oversight Committee, Section of Pediatric Gastroenterology, Hepatology and Nutrition, CHCO
2007 - 2022 Panel discussion member, Department of Pediatrics 2nd and 3rd year Fellowship Retreat, University of Colorado
2009 - 2022 Member, Pediatric Indirect Costs Request Committee, University of Colorado
2012 - 2021 Member, Pediatric 2ND Year Fellowship Scientific Writing Review, University of Colorado
2012 - 2021 Member, Pediatric Summer Student Research Internship Program, University of Colorado
2012 - 2016 Member, Department of Pediatrics Promotions Midpoint Review Committee, University of Colorado
2012 - 2013 Associate Director- Fellowship Training Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, CHCO
2013 - 2022 Director- Fellowship Training Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, CHCO
2013 - 2018 Member, Department of Pediatrics Research Institute Grant Review, University of Colorado
2014 - 2015 Member, Leadership for Innovative Team Science (LITeS), University of Colorado School of Medicine
2015 - 2022 Reviewer, Midpoint Internal Review of Internal Medicine- Pediatrics Residency Program, University of Colorado
2015 - 2016 Member, Department of Pediatrics Promotions Committee, University of Colorado
2015 - 2022 Reviewer, Colorado Clinical and Translational Sciences Institute Pre-K Program
2016 - 2022 Co-Chair, Department of Pediatrics Midpoint Promotions Review Committee, University of Colorado
2017 - 2022 Medical Director- Pediatric Liver Center, CHCO
2017 - 2018 Reviewer, Department of Medicine Outstanding Early Career Scholar Program, University of Colorado School of Medicine
2021 Member, Equity Certificate Program, University of Colorado Office of Diversity, Equity and Inclusion and Community Engagement
2022 member, Solid Organ Transplant Chief Search Committee, MCW, Froedtert Hosp., Children's WI
2022 Member, Surgeon-In-Chief Search Committee, MCW, Children's WI


NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2004 - Present Co-Investigator, Childhood Liver Disease Research Network (ChiLDReN)
2005 - 2008 Member, NASPGHAN Research Committee
2006 Member, NASPGHAN, Nominating Executive Committee
2009 - 2012 Chair, NASPGHAN, Hepatology Committee
2009 - 2014 Member, Regional Review Board, United Network of Organ Sharing
2011 - 2016 Regular Member, Digestive Diseases and Nutrition C Subcommittee of the Diabetes, Digestive and Kidney Diseases Initial Review Group, National Institute of Diabetes, Digestive and Kidney Diseases, NIH, Department of Health and Human Services
2012 - 2014 Member, AASLD Finance Committee
2013 Member, External Review Committee, University of California, Children's Hospital Los Angeles
2013 - 2016 Chair, AASLD Research Awards Committee (co-Chair in 2013)
2014 - 2016 Member, AASLD Foundation Board of Trustees
2015 - 2017 Chair, AASLD Special Interest Group (SIG) for Pediatric Liver Disorders
2017 - 2021 Chair, Data Safety Monitoring Board, Baylor College of Medicine and Texas Children's Hospital
2018 Member, AASLD Task Force
2018 - 2020 Member, Executive Council for NASPGHAN
2018 - 2020 Chair, AASLD Autoimmune Hepatitis Guidelines Committee
2018 - Present Chair, ChiLDReN Primary Sclerosing Cholangitis Working Group
2018 - Present Ad-hoc member, NIH NIDDK Hepatobiliary Pathophysiology Study Section
2020 - 2021 Member, AASLD Nominating Committee
2020 - Present Ad-hoc member, NIH NIDDK T32/ T35 Training Study Section.
2020 Member, External Review Committee, Children's Hospital of Philadelphia, Fred and Suzanne Biesecker Pediatric Liver Center.
2021 Pediatrics Representative, AASLD Scientific Program Committee
2022 Pediatrics Representative, AASLD-DDW Scientific Program Committee
2022 - 2023 Vice Chair, AASLD Cholestatic & Autoimmune Liver Diseases Special Interest Group


INTERNATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2006 - 2008 Member, World Congress- Federation of International Societies for Pediatric Gastroenterology, Hepatology and Nutrition Hepatology Committee

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:


Active
Peer Review
Title:	Colorado Center for Childhood Liver Disease Research Network- Subcontract
Source:	National Institutes of Health, NIDDK, 5 U01 DK062453
Role:	Co-Investigator
PI:	Sokol RJ
Dates:	09/15/2019 - 09/14/2024
Direct Funds:	$2,713,290

Title:	Mechanisms of neutrophil extracellular trap formation and contribution to fibrosis in biliary atresia
Source:	National Institutes of Health, NIDDK 5 U01 DK062453; ChiLDReN Translational Science Acceleration Supplement
Role:	PI
Dates:	07/01/2020 - 05/30/2022
Direct Funds:	$160,000

Title:	Diagnostic Biomarker Discovery in Pediatric Primary Sclerosing Cholangitis
Source:	Pediatric Liver Center Research Fund (patient/ family gift)
Role:	PI
Dates:	08/01/2021 - 07/30/2024
Direct Funds:	$100,000


Prior
Peer Review
Title:	Immunologic Mechanisms of Biliary Destruction in Biliary Atresia
Source:	National Institutes of Health, NIDDK, K08 DK60710-06
Role:	PI
Dates:	02/01/2002 - 12/30/2006
Direct Funds:	$500,000

Title:	Role of Cytokines and Autoimmunity in Murine Biliary Atresia
Source:	National Institutes of Health, NIDDK, R03 DK069818-01
Role:	PI
Dates:	09/30/2004 - 08/31/2006
Direct Funds:	$100,000

Title:	Role of Cytokines and Autoimmunity in Murine Biliary Atresia
Source:	March of Dimes Foundation, Basil O'Connor Starter Scholar Research Award
Role:	PI
Dates:	02/01/2005 - 07/31/2007
Direct Funds:	$150,000

Title:	Investigation of Pathogenic Autoreactive T cells in Biliary Atresia
Source:	American Liver Foundation, Biliary Atresia Research Initiative Grant
Role:	PI
Dates:	07/01/2006 - 06/30/2008
Direct Funds:	$200,000

Title:	T Cell-Mediated Mechanisms of Autoimmunity in Murine and Human Biliary Atresia
Source:	National Institutes of Health, NIDDK, 1 R01 DK078195-01
Role:	PI
Dates:	08/01/2007 - 07/30/2012
Direct Funds:	$922,500

Title:	Colorado Center for Childhood Liver Disease Research Network
Source:	NIH NIDDK; 5 U01 DK062453
Role:	Co-Investigator
Dates:	09/10/2009 - 09/09/2019
Direct Funds:	$3,933,196

Title:	T Cell-Mediated Mechanisms of Autoimmunity in Murine and Human Biliary Atresia
Source:	National Institutes of Health, NIDDK, NOT-OD09056 Recovery Act Funds for Admin. Suppl.
Role:	PI
Dates:	02/01/2010 - 01/31/2011
Direct Funds:	$66,900

Title:	Detection of HLA Predominance and Novel Shared Epitopes in Biliary Atresia
Source:	National Institutes of Health, NIDDK, 1 R56 DK087691-01
Role:	PI
Dates:	09/01/2010 - 02/31/2012
Direct Funds:	$225,000

Title:	A Pilot Withdrawal/Reinstitution Trial
Source:	FDA-OOP, R01 FD003709
Role:	Site PI
Dates:	2010 - 2018

Title:	Determining the importance of B cells to disease onset and progression in biliary atresia
Source:	Children's Hospital Colorado, CHC Research Institute for Bridge Funding
Role:	PI
Dates:	08/01/2012 - 07/30/2013
Direct Funds:	$100,000

Title:	The Role of Regulatory T Cells in the Pathogenesis of Murine Biliary Atresia
Source:	University of Colorado School of Medicine, Dean's Academic Enrichment Fund for Bridge Funding
Role:	PI
Dates:	08/01/2012 - 07/30/2013
Direct Funds:	$50,000

Title:	Significance of B cells and Humoral Immunity in the Pathogenesis of Biliary Atresia
Source:	National Institutes of Health, NIDDK, 1 R01 DK094937-01A1
Role:	PI
Dates:	06/01/2014 - 05/31/2019
Direct Funds:	$885,036

Title:	Institutional Training Grant in Pediatric Gastroenterology, University of Colorado
Source:	National Institutes of Health, NIDDK, 2T32 DK067009
Role:	MPI
Dates:	05/01/2015 - 01/31/2022
Direct Funds:	$1,928,845

Title:	Establishing an International Database for Pediatric PSC
Source:	Primary Sclerosing Cholangitis (PSC) Partners Seeking a Cure
Role:	Co-Investigator
Dates:	07/01/2017 - 06/30/2019
Direct Funds:	$100,000

Title:	Regulatory T cell dysfunction in biliary atresia
Source:	NASPGHAN Foundation/ Takeda Pharmaceutical Products Inc. Research Innovation Award, North American Society of Pediatric Gastroenterology, Hepatology and Nutrition Foundation
Role:	PI
Dates:	12/01/2017 - 11/30/2019
Direct Funds:	$150,000

Title:	Placebo controlled trial on the use of an ileal apical sodium bile acid transporter inhibitor (ASBTi) in progressive familial intrahepatic cholestasis.
Source:	Albireo Company
Role:	Site PI
Dates:	05/01/2019 - 01/31/2022

Title:	Role of the microbiome in biliary atresia-associated cholangitis
Source:	Baylor University, Texas Children's Hospital
Role:	Site PI
Dates:	08/01/2019 - 01/31/2022

Title:	The crosstalk of neutrophils and stellate cells in biliary atresia
Source:	University of Colorado GI & Liver Innate Immune Program
Role:	PI
Dates:	11/01/2019 - 10/31/2021
Direct Funds:	$25,000

Title:	A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Odevixibat (A4250) in Children with Biliary Atresia Who Have Undergone a Kasai Hepatoportoenterostomy
Source:	Albireo Company
Role:	Site PI
Dates:	12/10/2020 - 01/31/2022


INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Cara Mack, CHCO Liver Center- Family Symposium, University of CO School of Medicine, "Update on Pediatric Liver Diseases", Denver, Colorado, 2003 - 2004
Cara Mack, Topic Conferences, Section of Pediatric GI, Hepatology & Nutrition, CHCO, University of CO School of Medicine, Aurora, Colorado. Four individual 1 hour didactic sessions per year focused on a variety of liver disease topics including autoimmune hepatitis, neonatal cholestasis, management of biliary atresia, liver abscesses, infectious hepatitis, portal hypertension., 2003 - 2022
Cara Mack, Research in Progress, Section of Pediatric GI, Hepatology & Nutrition, CHCO, University of CO School of Medicine, Aurora, Colorado. Bi-annual update on my basic science and clinical research studies., 2003 - 2021
Cara Mack, Keynote Speaker, American Liver Foundation- local chapter, "Football Walk for Wellness", Denver, Colorado, 2006
Cara Mack, Department of Neonatology CME Series, CHCO, University of CO School of Medicine. "Neonatal Cholestasis", Aurora, Colorado, 2012
Cara Mack, CHCO Liver Center- Family Symposium- Riding it out with Liver Disease, "Latest Research in Liver Disease", Aurora, Colorado, 2013
Cara Mack, "Immunopathogenesis of Biliary Atresia", Mucosal Inflammation Program, Department of Medicine, University of CO School of Medicine, Aurora, Colorado, 2016
Cara Mack, "The Role of B cells and Humoral Immunity in the Pathogenesis of Biliary Atresia", Mucosal Inflammation Program, Department of Medicine, University of CO School of Medicine, Aurora, Colorado, 2017
Cara Mack, Presenter, Charting Pediatrics Podcast, CHCO, 2019
Cara Mack, "Regulatory T cell Dysfunction in Biliary Atresia", Mucosal Inflammation Program, Department of Medicine, University of CO School of Medicine, Aurora, Colorado, 2019
Cara Mack, Quarterly didactic topic conference presentations to faculty & GI fellows, Topics related to Research in Progress, Clinical Management of Biliary Atresia, AIH, PSC, Neonatal Cholestasis, Other, Children's Wisconsin, Division of Ped. GI, 2022 - Present

Regional
Cara Mack, The Integrated Department of Immunology Annual Retreat, "Biliary atresia is associated with CD4+ Th1 cell mediated inflammation", Denver, Colorado, 2003
Cara Mack, Research in Progress, Division of Allergy and Clinical Immunology, Department of Medicine, University of CO School of Medicine, Aurora, Colorado. Bi-annual update on our basic science research studies., 2003 - 2012
Cara Mack, Research in Progress, Perinatal Research Group, CHCO, University of CO School of Medicine. "Recent Investigations into Mechanisms of Bile Duct Injury in Biliary Atresia", Aurora, Colorado, 2010
Cara Mack, Research in Progress, Pelanda/Torres Lab Meeting, Department of Immunology, University of CO School of Medicine, Aurora, Colorado. Bi-annual update on our basic science research studies., 2014 - 2018
Cara Mack, Presenter, Children's Hospital Colorado Virtual CME Webinar, "The Jaundiced Infant- A Hepatologist's Perspective", Aurora, Colorado, 2021

National
Cara Mack, AASLD Annual Meeting, Plenary Session Oral Presentation, "Adoptive transfer of liver T cells from murine biliary atresia results in periductal infiltrates in recipient SCID mice suggesting autoimmune mediated bile duct injury", San Francisco, California, 2005
Cara Mack, NASPGHAN Annual Meeting, "Meet the Professor" session, "Biliary Atresia", Salt Lake City, Utah, 2005
Cara Mack, NASPGHAN Annual Meeting, "Meet the Professor" session, "Neonatal Cholestasis", Orlando, Florida, 2006
Cara Mack, NASPGHAN Annual Meeting, "Meet the Professor" session, "Drug Hepatotoxicity", Salt Lake City, Utah, 2006
Cara Mack, NIH Workshop: Screening and Outcomes in Biliary Atresia, "Viral and the Immunological Pathogenesis of Biliary Atresia", Bethesda, Maryland, 2006
Cara Mack, NASPGHAN Annual Meeting, Post-graduate Course- "Treatment Controversies in Biliary Atresia", Orlando, Florida, 2006
Cara Mack, AASLD Henry and Lillian Stratton Basic Research Single Topic Conference: Pathobiology of Biliary Epithelia and Cholangiocarcinoma, "Cholangiocytes as Targets of Immune-Mediated Injury and Immune Modulators in Biliary Atresia", Atlanta, Georgia, 2008
Cara Mack, University of Virginia School of Medicine, Department of Pediatrics Grand Rounds, "Current Investigations of Pathogenesis and Optimizing Outcomes in Biliary Atresia", Charlottesville, Virginia, 2008
Cara Mack, Baylor University School of Medicine, Department of Pediatrics, Pediatric Gastroenterology, Hepatology and Nutrition Research Conference, "Evidence for Virus-Induced Autoimmunity in the Pathogenesis of Biliary Atresia", Houston, Texas, 2009
Cara Mack, American Academy of Pediatrics, 76th Perinatal & Developmental Medicine Symposium: Gastrointestinal Tract Development and Congenital Anomalies, "Neonatal Cholestasis" and "Evidence for Viral-Induced Autoimmunity in the Pathogenesis of Biliary Atresia", Aspen, Colorado, 2010
Cara Mack, Pediatric Academic Societies & Asian Society for Pediatric Research Annual Meeting, Recent Advances in Neonatal Cholestatic Disorders, "Biliary Atresia: New Insights into Pathogenesis", Denver, Colorado, 2011
Cara Mack, Emory University School of Medicine, Department of Pediatrics, Transplant Grand Rounds, "Evidence for Immune-Mediated Bile Duct Injury in the Pathogenesis of Biliary Atresia", Atlanta, Georgia, 2011
Cara Mack, NASPGHAN Annual Meeting, State of the Art Lecture, "Biliary Atresia: New Insights into Pathogenesis", Orlando, Florida, 2011
Cara Mack, GI Research Seminar, The Children's Hospital of Philadelphia, Division of Pediatric GI, Hepatology and Nutrition, "Immune dysregulation in the pathogenesis of biliary atresia", Philadelphia, Pennsylvania, 2012
Cara Mack, NASPGHAN Annual Meeting, Meet the Professor Breakfast, "Career Development for Women in Academic Medicine", Salt Lake City, Utah, 2012
Cara Mack, Sabin Research Institute Research Symposium, USC Children's Hospital LA, "Deciphering the Role of Adaptive Immunity in the Pathogenesis of Biliary Atresia", Los Angeles, California, 2013
Cara Mack, Primary Sclerosing Cholangitis Partners Seeking A Cure- 10th Annual Conference: "New Potential Therapies for Pediatric PSC" and "Teens: Every Question is Fair Game", Greenwood Village, Colorado, 2014
Cara Mack, AASLD Annual Meeting, AASLD Postgraduate Course - Clinical Implications of Inflammation and Immunity in Acute and Chronic Liver Disease, "Biliary Atresia: Mechanisms of Immune-Mediated Biliary Injury and Fibrosis", Boston, Massachusetts, 2014
Cara Mack, NASPGHAN Annual Meeting, State of the Art Lecture, "Unique Aspects of Neonatal Immunity Provide Clues to Etiology of Biliary Atresia", Washington D.C., 2015
Cara Mack, AASLD Annual Meeting, NASPGHAN/AASLD Pediatric Liver Disease Symposium, "Mechanisms of Liver Injury in Biliary Atresia", Boston, Massachusetts, 2016
Cara Mack, Mayo Clinic Rochester, Department of Pediatrics Grand Rounds, "Unique Aspects of the Neonatal Immunity Provide Clues to Etiology of Biliary Atresia", Rochester, Minnesota, 2016
Cara Mack, Childhood Liver Disease Research Network, "Autoantibody Microarray to Identify Autoantibodies in Biliary Atresia", Alexandria, Virginia, 2016
Cara Mack, AASLD/FDA Conference on Trial Design and Endpoints for Clinical Trial in Adults and Children with Primary Sclerosing Cholangitis, "A Critical Appraisal of Biomarkers That Can Be Used to Identify Subpopulations in Pediatric PSC", Silver Spring, Maryland, 2016
Cara Mack, NIH/ NIDDK Workshop. Biliary Atresia: A Clinical and Translational Science Research Workshop, "Autoimmunity in Biliary Atresia", Bethesda, Maryland, 2017
Cara Mack, AASLD Annual Meeting, Early Morning Workshop, "Update on Evidence for Pathogenesis of Biliary Atresia", Washington D.C., 2017
Cara Mack, NASPGHAN Annual Meeting, Post Graduate Course, "Update on Diagnostic and Prognostic Biomarkers and Therapeutic Interventions in Biliary Atresia", Las Vegas, Nevada, 2017
Cara Mack, NASPGHAN Annual Meeting, "Meet the Professor" session, "Diagnostic Workup of Neonatal Cholestasis", Las Vegas, Nevada, 2017
Cara Mack, AASLD Annual Meeting, Early Morning Workshop, "New Insights in Management of Primary Sclerosing Cholangitis", San Francisco, California, 2018
Cara Mack, Childhood Liver Disease Research Network, "Clinical Trial Design for Pediatric Primary Sclerosing Cholangitis", Alexandria, Virginia, 2018
Cara Mack, NASPGHAN Annual Meeting, Early Morning Workshop session, "Career Development and Promotion", Hollywood, Florida, 2018
Cara Mack, AASLD Annual Meeting, AASLD Postgraduate Course, "Biliary Atresia: Biomarkers of Disease and Predictors of Outcome", Boston, MA, 2019
Cara Mack, NASPGHAN Annual Meeting, Single Topic Symposium, Chronic Liver Disease Management for the General Gastroenterologist, "Group Discussion of Difficult Cases", Chicago, IL, 2019
Cara Mack, NASPGHAN Annual Meeting, Concurrent Session- Chronic Hepatitis, "Regulatory T Cell Dysfunction in Biliary Atresia", Chicago, IL, 2019
Cara Mack, NASPGHAN Annual Meeting, Meet the Professor session, "Autoimmune Hepatitis", Chicago, IL, 2019
Cara Mack, 7th Annual Pediatric IBD Research Day, Weill Cornell Medicine, "Pathophysiology of Liver Disease in IBD", NY, NY, 2019
Cara Mack, PSC Partners Seeking a Cure, Webinar Series, "Update on Pediatric PSC", https://youtu.be/AyC7d6QfBjw, Denver, CO, 2020
Cara Mack, NASPGHAN Annual Meeting, Concurrent Session- Guidelines, "AASLD Guidance and Guidelines for AIH in Adults and Children", Virtual Meeting, 2020
Cara Mack, PFIC Advocacy and Research Network, PFIC 101 Webinar, Organizer and Speaker for 2 talks: "PFIC 101: How genetic mutations lead to disease", "Clinical Trial Considerations and Future Therapies for PFIC", Virtual Meeting, 2020
Cara Mack, AASLD Annual Meeting, Cholestatic and Autoimmune Liver Diseases Special Interest Group Session, "What Is New in Pediatric PSC", Virtual Meeting, 2020
Cara Mack, AASLD/ NASPGHAN Pediatric Symposium, "Approach and Treatment of Typical Cases of Autoimmune Hepatitis", AASLD- The Liver Meeting, Virtual Meeting, 2021
Cara Mack, The Second Annual Pediatric Liver Disease and Transplantation Symposium, Advance Management of Biliary Atresia Webinar, Columbia University Irving Medical Center, "Innate Immune Activation in the Pathogenesis of Biliary Atresia", Virtual Meeting, 2021
Cara Mack, The Autoimmune Hepatitis Association Conference, "Guidelines for AIH- How we create them and why we need them", Indianapolis, IN, Virtual Meeting, 2021
Cara Mack, AAP 4th Year Transplant Hepatology Fellowship Program, "Update on Management of AIH and PSC", Virtual Meeting, 2022

International
Cara Mack, NASPGHAN Annual Meeting, Post-graduate Course- "Optimizing Outcomes in Biliary Atresia", Montreal, Canada, 2003
Cara Mack, NASPGHAN Annual Meeting, "Meet the Professor" session, "Portal Hypertension", Montreal, Canada, 2003
Cara Mack, Division of Pediatric GI, Hepatology and Nutrition Research Seminar, "Immunopathogenesis of Biliary Atresia", Sick Children's Hospital and University of Toronto, Toronto, Canada, 2008
Cara Mack, 7th International Sendai Symposium on Biliary Atresia, "Update on Investigations Pertaining to the Pathogenesis of Biliary Atresia", Sendai Conference on Biliary Atresia, Sendai, Japan, 2017
Cara Mack, Juntendo University Graduate School of Medicine, Department of Pediatrics Visiting Professor, "Unraveling the Pathogenesis of Biliary Atresia in Order to Optimize Outcomes", Tokyo, Japan, 2017
Cara Mack, National Taiwan University Children's Hospital, Department of Pediatrics Visiting Professor, "Recent Investigations in the Immunopathogenesis of Biliary Atresia", Taipei, Taiwan, 2018
Cara Mack, Annual Meeting of the Taiwan Society of Pediatric Gastroenterology, Hepatology and Nutrition, "Recent Advances in the Management of Cholestatic Liver Diseases in Children", Tainan, Taiwan, 2018
Cara Mack, Sick Kids Hospital Gastroenterology, Hepatology and Nutrition Research Day, "Recent Advances in Deciphering the Immunopathogenesis of Biliary Atresia", Toronto, Canada, 2019
Cara Mack, Sick Kids Hospital Gastroenterology, Hepatology and Nutrition Research Day, "Faculty Leader: Poster Walks- Liver Disease Research", Toronto, Canada, 2019
Cara Mack, World Congress of Pediatric Gastroenterology, Hepatology and Nutrition, "Biliary Atresia- Closer to Pathogenesis", Virtual Meeting, 2021


PEER REVIEWED WORKSHOPS/PRESENTATIONS:
National
SEE ABOVE UNDER INVITED LECTURES/WORKSHOPS/PRESENTATIONS


COMMITTEE SERVICE:
Hospital
See Local/ Regional Committee Positions above for information on committees associated with hospital/ university


EXTRAMURAL TEACHING:
Medical Student Education
08/01/2002 - 01/31/2022 University of Colorado School of Medicine, -Bi-annual presentation of case studies in gastrointestinal pathophysiology (small group discussions) -Lectures (10 times/year) to students on GI in-service rotations

Resident and Fellow Education
08/01/2002 - 01/31/2022 Children's Hospital Colorado, Residents - Lectures (10 times/year) to interns and residents on GI in-service rotations GI fellows -Quarterly formal lectures on pediatric liver diseases, Fellows’ Core Lecture Series, Section of GI & Hepatology Ward/clinic attending duties: Supervision and bedside teaching of medical students, residents and GI fellows, Inpatient Service, 10 weeks per year and outpatient Liver Clinic, 6-8 clinics/month
02/01/2022 - Present Children's Wisconsin, Medical College of Wisconsin, Residents - Lectures to interns and residents on Hepatology inpatient rotations GI fellows -Quarterly formal lectures on pediatric liver diseases, Fellows’ Core Lecture Series, Section of GI & Hepatology Ward/clinic attending duties: Supervision and bedside teaching of medical students, residents and GI fellows, Inpatient Service, 8 weeks per year and outpatient Liver Clinic, 4 clinics/month


EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
Undergraduate Students
Matthew Smith, University of Colorado School of Medicine, 06/01/2011 - 08/30/2011 research advisor, Identification of complement in experimental biliary atresia
Melissa Berg, University of Colorado School of Medicine, 06/01/2013 - 08/30/2013 research advisor, Identification of innate immune cytokines in biliary atresia
Ilona Schwarz, University of Colorado School of Medicine, 06/01/2016 - 08/30/2016 research advisor, Assessment of changes in bile acid transporter in response to liver virus infection
Caroline Smith, University of Colorado School of Medicine, 06/01/2017 - 08/30/2018 research advisor, 1 publication

Medical Students
Juri Boguniewicz, University of Colorado, 03/01/2009 - 05/30/2013 research advisor, publication- IVIg treatment in biliary atresia

Graduate Students
MS Committees
Julia Boster, University of Colorado School of Medicine, 06/01/2018 - 05/30/2020 Outcomes of hepatoblastoma and liver transplant, 1 publication
Sarah Kemme, University of Colorado School of Medicine, 06/01/2020 - 05/30/2021 CMV infection and outcomes in biliary atresia, 1 MIP
MS Students Advised
Dor Yoeli, University of Colorado School of Medicine, 05/01/2021 - 05/30/2022 Role of galectin-3 in biliary atresia, 1 MIP

Postdoctoral Students
Fabian Wehrmann, MD, University of Colorado School of Medicine, 09/01/2007 - 05/30/2009 research advisor, research project: “Determine antigen specificity and effector function of autoantibodies generated from B cell hybridomas in murine biliary atresia”

Clinical/Research Fellows
Barrett Barnes, University of Colorado School of Medicine, 07/01/2005 - 06/30/2007 research advisor, 1 publication
Brandy Lu, University of Colorado School of Medicine, 07/01/2007 - 06/30/2009 research advisor, 1 publication
Amy Feldman, University of Colorado School of Medicine, 07/01/2011 - 06/30/2013 research advisor, 1 publication
Melissa Sheiko, University of Colorado School of Medicine, 06/01/2013 - 06/01/2015 research advisor, 1 publication
27 fellows trained, University of Colorado School of Medicine and Children's Hospital Colorado, 07/01/2013 - 01/31/2022 career advisement and scholarship oversight based on director of fellowship role and T32 program director, 80% of fellow grads remain in academics; 30% remain in research related careers
Joseph Bednarek, University of Colorado School of Medicine, 07/01/2015 - 07/30/2019 research advisor, 2 publications; attainment of graduate school admission
Dania Brigham, University of Colorado School of Medicine, 07/01/2015 - 06/30/2017 research advisor, 1 publication
Sarah Kemme, University of Colorado School of Medicine, 07/01/2021 - 06/01/2022 Sarah Kemme, 1 MIP

Residents
Brandy Lu, University of Colorado School of Medicine, 08/01/2005 - 12/30/2005 research advisor, 1 publication
Jillian Mayer, University of Colorado School of Medicine, 05/01/2015 - 08/01/2017 research advisor, 1 publication
Michelle Corrado, University of Colorado School of Medicine, 03/01/2020 - 06/01/2021 research advisor, Role of HMGB1 in innate immune activation in biliary atresia
Dor Yoeli, University of Colorado School of Medicine, 05/01/2021 - 06/01/2022 research advisor, 2021 CU CCTSI Team Oriented Training Across Translational Sciences TL1 Award. 2021 AASLD Emerging Liver Scholar award.

Faculty
Richard Hendrickson, University of Colorado School of Medicine, 01/01/2005 - 01/01/2006 research advisor, 1 publication
Jonathan Roach, University of Colorado School of Medicine, 08/01/2014 - 08/01/2018 research advisor, 1 publication


PROGRAMMATIC DEVELOPMENTS:
Educational Programs
Fellow
2007 - 2016 2007, 2008, 2009, 2016 Faculty, NASPGHAN Peds GI Fellows Confs.
2013 - 2022 Director- Fellowship Training Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition. Maintenance of T32 training grant.
Faculty
2011 Course Director of AASLD/NASPGHAN symposium, Update on Pediatric Autoimmune Liver Diseases, AASLD Annual Meeting, San Francisco, CA
2014 Course Director and Moderator: Special Interest Group Symposium, AASLD Annual Meeting, Controversies in the Management of Primary Sclerosing Cholangitis in Children and Adults, Boston, MA


COMMUNITY SERVICE ACTIVITIES:
2003 - 2004 Speaker at "Update on Pediatric Liver Diseases", The Children's Hospital Liver Center, weekend symposium for families of children with liver disease, Denver, CO
2006 Keynote Speaker, American Liver Foundation- local chapter, "Football Walk for Wellness" Fundraiser Event, Denver, CO
2012 - 2013 Organizer of Children's Hospital Colorado team for local annual fundraising event for liver research: "Kickin' for Kids" kickball tournament, Boulder, CO
2013 Speaker at CHCO Liver Symposium for families with pediatric liver disease ("Riding it out with Liver Disease"). Didactic lecture on "Latest Research in Liver Disease", Aurora, CO
2014 Speaker at the PSC Partners Seeking A Cure 10th Annual Conference: "New Potential Therapies for Pediatric PSC" and "Teens: Every Question is Fair Game", Denver, CO
2018 Speaker, American Liver Foundation/ Digestive Health Institute/ CHCO "Pediatric Liver Center: Ask the Experts", June 30, 2018.
2019 Speaker, Progressive Familial Intrahepatic Cholestasis Advocacy and Resource Network, Inc. and Albireo Company. Video presentation to increase awareness of PFIC disease in community.
2020 Speaker, Progressive Familial Intrahepatic Cholestasis Advocacy and Resource Network, Inc. and Albireo Company. Video presentation to increase awareness of impact of PFIC disease on patients and famil
2020 Speaker, PSC Partners Seeking a Cure Podcast on Pediatric PSC: https://www.dropbox.com/s/tl4z9nym3mtwom2/episode_19_dr.%20cara%20mack.mp3?dl=0
2021 Moderator, PSC Partners Seeking a Cure, ROADMAP webinar, "The PSC Research Landscape: Now and Into the Future: Identifying Research Questions"
2021 Speaker, Children's Hospital Colorado Provider Education Video, "Update on Management of Autoimmune Hepatitis" (CHCO website and YouTube)
2021 Moderator, PSC Partners Seeking a Cure, ROADMAP webinar, "The PSC Research Landscape: Now and Into the Future: Five Concepts in PSC"


GLOBAL HEALTH ACTIVITIES:
2016 Volunteer- surgical assistant, Northwest Haiti Christian Medical Mission, June 19-25, 2016.
2017 Volunteer- general pediatric care in rural settings, Northwest Haiti Christian Medical Mission, June 12-24, 2017.


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Mack CL, Millis JM, Whitington PF, and Alonso EM Pulmonary Complications Following Liver Transplantation in Pediatric Patients. Pediatr Transplant 2000;4:39-44. PMID: 10731057
2. Mack CL, Kavorik P and Emerick KM. Early Speech Delay and Hepatitis as Presenting Signs of Homocystinuria, J Pediatr Gastroenterol Nutr 2001;33(2):221-23.
3. Mack CL, Ferrario M, Abecassis M, Whitington PF, Superina RA, Alonso EM. Living Donor Liver Transplantation for Children in Liver Failure and Concurrent Multiple Organ System Failure. Liver Transplant 2001;7:890-895. PMID: 11679988.
4. Mack CL, Superina RA, Whitington PF. Surgical Restoration of Portal Flow Corrects Procoagulant and Anticoagulant Deficiencies Associated with Extrahepatic Portal Vein Thrombosis. J Peds 2003;142(2):197-9. PMID: 12584545
5. Mack CL, Neville K, Miller SD. Microglia are Transformed into Competent Antigen Presenting Cells and Effector Cells in a Murine Model of Multiple Sclerosis. Jrl Neuroimmun 2003;144(1-2):68-79. PMID: 14597100
6. Zhang DY, Sabla G, Shivakumar P, Tiao G, Sokol RJ, Mack C, Shneider BL, Aronow B, Bezerra JA. Coordinate expression of regulatory genes differentiates embryonic and perinatal forms of biliary atresia. Hepatology 2004;39(4):954-62. PMID: 15057899
7. Mack CL, Tucker R, Sokol RJ, Karrer FM, Kotzin B, Whitington PF, Miller SD. Biliary Atresia is Associated with CD4+, Th1 Cell Mediated Portal Tract Inflammation. Pediatr Res 2004; 56(1):79-87. PMID: 15128911, PMCID: PMC1948976
8. Whitington PF, Malladi P, Melin-Aldana H, Azzam R, Mack CL and Sahai A. Expression of osteopontin correlates with portal biliary proliferation and fibrosis in biliary atresia. Pediatr Res 2005;57(6):837-844. PMID: 15845635
9. Mack CL, Tucker RM, Sokol RJ, Kotzin BL. Armed CD4+ Effector Cells and Activated Macrophages Participate in Bile Duct Injury in Murine Biliary Atresia. Clin Immunol 2005;115(2):200-209. PMID: 15885644, PMCID: PMC1950158
10. Mack CL, Zelko FA, Lokar J, Superina RM, Alonso EM, Blei AT and Whitington PF. Surgically Restoring Portal Blood Flow to the Liver in Children with Primary Extrahepatic Portal Vein Thrombosis Improves Fluid Neurocognitive Ability. Pediatrics 2006;117(3):405-412. PMID: 16481447
11. Whitworth JR, Mack CL, O'Connor JA, Narkewicz MR, Mengshol S, Sokol RJ. Acute hepatitis and liver failure associated with influenza A infection in children. J Pediatr Gastroenterol Nutr 2006;43(4):536-8. PMID: 17033532
12. Mack CL, Tucker RM, Lu BR, Sokol RJ, Fontenot AP, Ueno Y and Gill RG, Cellular and Humoral Autoimmunity Directed at Bile Duct Epithelia in Murine Biliary Atresia, Hepatology 2006;44:1231-1239. PMID: 17058262, PMCID: PMC1948978
13. Tucker RM, Hendrickson RJ, Mukaida N, Gill RG and Mack CL. Progressive Biliary Destruction in the Absence of a Functional Tumor Necrosis Factor-alpha Pathway in a Murine Model of Biliary Atresia. Viral Immunol 2007;20(1):34-43. PMID: 17425419, PMCID: PMC1978183
14. Mack CL, Falta MT, Sullivan AK, Karrer F, Sokol RJ, Fontenot AP, Oligoclonal Expansions of CD4+ and CD8+ T Cells in the Target Organ of Patients with Biliary Atresia, Gastroenterology. 2007;133(1):278-287. PMID: 17631149, PMCID: PMC1949019
15. Sokal EM, Goldstein D, Ciocca M, Lewindon P, Ni YH, Silveira T, Sibal A, Dhawan A, Mack C, Bucuvalas J; End-Stage Liver Disease Working Group. End-stage liver disease and liver transplant: current situation and key issues. J Pediatr Gastroenterol Nutr 2008;47(2):239-46.
16. Barnes BH, Tucker RM, Wehrmann F, Mack DG, Ueno Y, Mack CL. Cholangiocytes as immune modulators in rotavirus-induced murine biliary atresia. Liver Int 2009;29(8):1253-61. PMID: 19040538, PMCID: PMC3783657
17. Rand EB, Karpen SJ, Kelly S, Mack CL, Malatack JJ, Sokol RJ, Whitington PF. Treatment of neonatal hemochromatosis with exchange transfusion and intravenous immunoglobulin. J Pediatr 2009;155(4):566-71. PMID: 19560784
18. Lu BR, Brindley SM, Tucker RM, Lambert CL, Mack CL. Alpha-enolase autoantibodies cross-reactive to viral proteins in a mouse model of biliary atresia. Gastroenterology 2010; 139(5):1753-61. PMID: 20659472, PMCID: PMC3792016
19. Law YM, Mack CL, Sokol RJ, Rice M, Parsley L, Ivy D. Cardiopulmonary manifestations of portovenous shunts from congenital absence of the portal vein: Pulmonary hypertension and pulmonary vascular dilatation. Pediatr Transplant 2011;15(8):E162-8. PMID: 20565694, PMCID: PMC3203339
20. Brindley SM, Martin A, Tucker RM, Karrer F, Fontenot AP, Mack CL. Cytomegalovirus-specific T cell reactivity in biliary atresia at the time of diagnosis is associated with deficits in regulatory T cells. Hepatology 2012;55(4):1130-8. PMID: 2105891, PMCID: PMC3319336
21. Tucker RM and Mack CL. Generation of a cholangiocytes specific cDNA expression library for the identification of B and T cell autoantigens in murine biliary disease. Hepatol Res 2012;42(5):502-7. PMID: 22236071, PMCID: PMC3798039
22. Mack CL, Gonzalez-Peralta RP, Gupta N, Leung D, Narkewicz MR, Roberts EA, Rosenthal P, Schwarz KB. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Practice Guidelines: Diagnosis and Management of Hepatitis C Infection in Infants, Children and Adolescents. J Pediatr Gastroenterol Nutr 2012;54(6):838-55. PMID: 22487950
23. Mack CL, Anderson KM, Aubrey MT, Rosenthal P, Sokol RJ, Freed BM. Lack of HLA predominance and HLA shared epitopes in biliary Atresia. SpringerPlus 2013;2(1):42. PMID: 23505615, PMCID: PMC3595468
24. Schwarz KB, Haber BH, Philip R, Mack CL, Jeffrey M, Kevin B, Bezerra JA, Karpen SJ, Nanda K, Shneider BL, Turmelle YP, Whitington PF, Molleston JP, Murray KF, Ng VL, René R, Wang KS, Sokol RJ, Magee JC; for the Childhood Liver Disease Research and Education Network. Extra-hepatic anomalies in infants with biliary atresia: results of a large prospective North American multi-center study. Hepatology. 2013;58(5):1724-31. PMID: 23703680, PMCID: PMC3844083
25. Tucker RM, Feldman AG, Fenner EK, Mack CL. Regulatory T cells inhibit Th1 cell-mediated bile duct injury in murine biliary atresia. J Hepatol. 2013;59(4):790-6. PMID: 23685050, PMCID: PMC3855478
26. Feldman AG, Tucker RM, Fenner EK, Pelanda R, Mack CL. B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia. PLoS One. 2013;8(8):e73644. PMID: 23991203, PMCID: PMC3749125
27. Siberry GK, Abzug MJ, Nachman S, Bohannon B, Brady MT, Dominguez KL, Handelsman E, Mofenson LM, Nesheim S, Bhattacharya D, Clarke D, Esbenshade JC, Edwards KM, Flynn P, Gaur A, Gigliotti F, Harrison G, Hobbs CV, Kimberlin D, Kleiman MB, Koumans EH, Kroger A, Levin MJ, Mack CL, Marais B, Maron G, McAuley J, Menzies HJ, Moscicki AB, Narkewicz M, Rutstein R, Seward J, Shimamura M, Steinbach WJ, Wilson GJ. Executive summary: 2013 update of the guidelines for the prevention and treatment of opportunistic infections in HIV-exposed and HIV-infected children. Pediatr Infect Dis J. 2013;32(12):1303-07. PMID: 24569304, PMCID: PMC3937852
28. Siberry GK, Abzug MJ, Nachman S, Brady MT, Dominguez KL, Handelsman E, Mofenson LM, Nesheim S, Bhattacharya D, Bohannon B, Clarke D, Edwards KM, Esbenshade JC, Flynn P, Gaur A, Gigliotti F, Harrison G, Hobbs CV, Kimberlin D, Kleiman MB, Koumans EH, Kroger A, Levin MJ, Mack CL, Marais BJ, Maron G, McAuley J, Menzies HJ, Moscicki AB, Narkewicz MR, Rutstein R, Seward J, Shimamura M, Steinbach WJ, Wilson GJ. Guidelines for the prevention and treatment of opportunistic infections in HIV-exposed and HIV-infected children: recommendations from the National Institutes of Health, Centers for Disease Control and Prevention, the HIV Medicine Association of the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics. Pediatr Infect Dis J. 2013;32 Suppl 2. PMID: 24569199, PMCID: PMC3937852
29. Fenner E, Boguniewicz J, Tucker RM, Feldman A, Mack CL. High dose intravenous immunoglobulin abrogates biliary obstruction in a mouse model of biliary atresia. Pediatr Res 2014;76(1):72-80. PMID: 24727948. PMCID: PMC4062601
30. Bezerra JA, Spino C, Magee JC, Shneider BL, Rosenthal P, Wang KS, Erlichman J, Haber B, Hertel PM, Karpen SJ, Kerkar N, Loomes KM, Molleston JP, Murray KF, Romero R, Schwarz KB, Shepherd R, Suchy FJ, Turmelle YP, Whitington PF, Moore J, Sherker AH, Robuck PR, Sokol RJ; Childhood Liver Disease Research and Education Network (ChiLDREN;...Mack C...). Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial. JAMA. 2014;311(17):1750-9. PMID: 24794368
31. Ng VL, Haber BH, Magee JC, Miethke A, Murray KF, Michail S, Karpen SJ, Kerkar N, Molleston JP, Romero R, Rosenthal P, Schwarz KB, Shneider BL, Turmelle YP, Alonso EM, Sherker AH, Sokol RJ; Childhood Liver Disease Research and Education Network (CHiLDREN;...Mack C...). Medical status of 219 children with biliary atresia surviving long-term with their native livers: results from a North American multicenter consortium. J Pediatr. 2014;165(3):539-546.
32. Kamath BM, Chen Z, Romero R, Fredericks EM, Alonso EM, Arnon R, Heubi J, Hertel PM, Karpen SJ, Loomes KM, Murray KF, Rosenthal P, Schwarz KB, Subbarao G, Teckman JH, Turmelle YP, Wang KS, Sherker AH, Sokol RJ, Magee JC; Childhood Liver Disease Research Network (ChiLDReN;...Mack C...). Quality of Life and Its Determinants in a Multicenter Cohort of Children with Alagille Syndrome. J Pediatr 2015;167(2):390-6. PMID: 26059338
33. Shneider BL, Magee JC, Karpen SJ, Rand EB, Narkewicz MR, Bass LM, Schwarz K, Whitington PF, Bezerra JA, Kerkar N, Haber B, Rosenthal P, Turmelle YP, Molleston JP, Murray KF, Ng VL, Wang KS, Romero R, Squires RH, Arnon R, Sherker AH, Moore J, Ye W, Sokol RJ; Childhood Liver Disease Research Network (ChiLDReN;...Mack C...). Total Serum Bilirubin within 3 Months of Hepatoportoenterostomy Predicts Short-Term Outcomes in Biliary Atresia. J Pediatr. 2016;170:211-217. PMID: 26725209
34. Sheiko MA, Golden-Mason L, Giugliano S, Waasdorp-Hurtado C, Mack CL, Narkewicz M, Rosen HR. CD4+ and CD8+ T Cell Activation in Children with Hepatitis C, J Pediatr 2016;170:142-48. PMID: 26743497
35. Fawaz R, Baumann U, Ekong U, Fischler B, Hadzic N, Mack CL, McLin V, Molleston JP, Neimark E, Ng VL, Karpen SJ. Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), J Pediatr Gastroenterol Nutr 2017;64(1):154-168. PMID: 27429428
36. Sundaram SS, Mack CL, Feldman AG, Sokol RJ. Biliary Atresia: Indications and Timing of Liver Transplantation and Optimization of Pre-Transplant Care. Liver Transpl 2017;23(1):96-109.PMID: 27650268
37. Wang KS, Tiao G, Bass LM, Hertel PM, Mogul D, Kerkar N, Clifton M, Azen C, Bull L, Rosenthal P, Stewart D, Superina R, Arnon R, Bozic M, Brandt ML, Dillon PA, Fecteau A, Iyer K, Kamath B, Karpen S, Karrer F, Loomes KM, Mack C, Mattei P, Miethke A, Soltys K, Turmelle YP, West K, Zagory J, Goodhue C, Shneider BL; The Childhood Liver Disease Research Network (ChiLDReN). Analysis of surgical interruption of the enterohepatic circulation as a treatment for pediatric cholestasis. Hepatology. 2017;65(5):1645-1654. PMID: 28027587
38. Sheiko MA, Sundaram SS, Capocelli KE, Pan Z, McCoy AM, Mack CL. Outcomes in Pediatric Autoimmune Hepatitis and Significance of Azathioprine Metabolites. J Pediatr Gastroenterol Nutr. 2017;65(1):80-85. PMID: 28272159
39. Deneau M, El-Matary W, Valentino P, Abdou R, Alqoaer K, Amin M, Amir A, Auth M, Bazerbachi F, Broderick A, Chan A, Cotter J, Doan S, El-Youssef M, Ferrari F, Furuya K, Gottrand F, Gottrand M, Gupta N, Homan M, Kamath B, Kim KM, Kolho K, Konidari A, Koot B, Iorio R, Ledder O, Mack C, Marotine M, Miloh T, Mohan P, OCathain N, Papdopoulou A, Ricciuto A, Saubermann L, Sathya P, Shteyer E, Smolka V, Tanaka A, Varier R, Venkat V, Vitola B, Vos M, Woynarowski M, Yap J, Jensen MK. The natural history of primary sclerosing cholangitis in 781 children: an international, multicenter collaboration. Hepatology 2017;66(2):518-27. PMID: 28390159
40. Mark JA, Mack CL, Marwan AI, Kramer RE. Use of fully covered self-expanding metal biliary stents in pediatrics: a case series. J Pediatr Gastroenterol Nutr 2018;66(3):71-75. PMID: 28837510
41. Cotter J, Browne L, Capocelli K, McCoy A, Mack CL. Lack of correlation of liver tests with fibrosis stage at diagnosis in pediatric primary sclerosing cholangitis. J Pediatr Gastroenterol Nutr 2018;66(2):227-233. PMID: 29356767
42. Ng VL, Sorensen LG, Alonso EM, Fredericks EM, Ye W, Moore J, Karpen SJ, Shneider BL, Molleston JP, Bezerra JA,Murray KF, Loomes KM, Rosenthal P, Squires RH, Wang K, Arnon R, Schwarz KB, Turmelle YP, Haber BH, Sherker AH, Magee JC, Sokol RJ; Childhood Liver Disease Research Network (ChiLDReN... Mack CL...). Neurodevelopmental Outcome of Young Children with Biliary Atresia and Native Liver: Results from the ChiLDReN Study. J Pediatr. 2018;196:139-147. PMID: 29519540
43. Bednarek J, Traxinger B, Brigham D, Roach J, Orlicky D, Wang D, Pelanda R, Mack CL. Cytokine-producing B cells promote immune-mediated bile duct injury in murine biliary atresia. Hepatology 2018;68(5):1890-1904. PMID: 29679373
44. Bezerra JA, Wells RG, Mack CL, Karpen SJ, Hoofnagle JH, Doo E, Sokol RJ. Biliary atresia: Clinical and research challenges for the 21st century. Hepatology 2018;68(3):1163-1173. PMID: 29604222
45. Alonso EM, Ye W, Hawthorne K, Venkat V, Loomes KM, Mack CL, Hertel PM, Karpen SJ, Kerkar N, Molleston JP, Murray KF, Romero R, Rosenthal P, Schwarz KB, Shneider BL, Suchy FJ, Turmelle YP, Wang KS, Sherker AH, Sokol RJ, Bezerra JA, Magee JC; ChiLDReN Network. Impact of Steroid Therapy on Early Growth in Infants with Biliary Atresia: The Multicenter Steroids in Biliary Atresia Randomized Trial. J Pediatr. 2018;202:179-185. PMID: 30244988
46. Shneider BL, Spino C, Kamath BM, Magee JC, Bass LM, Setchell KD, Miethke A, Molleston JP, Mack CL, Squires RH, Murray KF, Loomes KM, Rosenthal P, Karpen SJ, Leung DH, Guthery SL, Thomas D, Sherker AH, Sokol RJ; Childhood Liver Disease Research Network. Placebo-Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome. Hepatol Commun. 2018;2(10):1184-1198. PMID: 30288474
47. Deneau MR, Mack CL, Abdou R, Amin M, Amir A, Auth M et al. GGT reduction is associated with favorable outcomes in pediatric PSC. Hepatol Commun 2018;2(11):1369-78. PMID: 30411083
48. Mack CL, Spino C, Alonso EA, Bezerra JA, Moore J, Goodhue C, Ng V, Karpen SJ, Venkat V, Loomes K, Wang K, Sherker A, Magee J, Sokol RJ and the ChiLDReN Network. A Phase I/IIa trial of intravenous immunoglobulin therapy following portoenterostomy in infants with biliary atresia (PRIME study). J Pediatr Gastroenterol Nutr 2019;68(4):495-501. PMID: 30664564
49. Kim S, Moore J, Alonso E, Bednarek J, Bezerra JA, Goodhue C, Karpen SJ, Loomes KM, Magee JC, Ng VL, Sherker AH, Smith C, Spino C, Venkat V, Wang K, Sokol RJ, Mack CL and the Childhood Liver Disease Research Network. Correlation of Immune Markers with Outcomes in Biliary Atresia Following Intravenous Immunoglobulin Therapy. Hepatol Commun 2019;3(5):685-696. PMID: 31061956
50. Jaramillo C, Gilani A, Haag M, Donaldson N, Mack CL. Synovial Cell Sarcoma in an Adolescent Liver Transplant Recipient. ACG Case Rep J. 2019;6(5):e00091. PMID: 31616756
51. Taylor SA, Assis DN, Mack CL. The Contribution of B Cells in Autoimmune Liver Diseases. Semin Liver Dis 2019;39(4):422-31. PMID: 31226726, PMCID: PMC6800599
52. Deneau M, Perito E, Ricciuto A, Gupta N, Kamath BM, Vitola B, Smolka V, Ferrari F, Amir AZ, Miloh T, Papadopoulou A, Mohan P, Mack C, Kolho KL, Iorio R, El-Matary W, Venkat V, Chan A, Saubermann L, Valentino PL, Shah U, Miethke A, Lin H, Jensen MK. Ursodeoxycholic Aicd Therapy in Pediatric Primary Sclerosing Cholangitis: Predictors of GGT Normalization and Favorable Clinical Course. J Pediatr 2019;209:92-96. PMID: 30878206
53. Black D, Mack C, Kerkar N, Miloh T, Sundaram S, Anand R, Gupta A, Alonso E, Arnon R, Bulut P, Karpen S, Lin CH, Rosenthal P, Ryan M, Squires R, Valentino P, Elsea S, Shneider BL. A Prospective Trial of Withdrawal and Reinstitution of Ursodeoxycholic Acid in Pediatric Primary Sclerosing Cholangitis (WUPPSC). Hepatol Commun 2019;3(11):1482-1495. PMID: 31701072, PMCID: PMC6824074
54. Feldman AG, Hsu EK, Mack CL. The Importance of Prioritizing Pre- and Post-Transplant Immunizations in An Era of Vaccine Refusal and Epidemic Outbreaks. Transplantation 2020;104(1):33-38. PMID: 31876696
55. Deneau M, Valentino P, Mack C, Alqoaer K, Amin M, Amir A, Aumar M, Auth M, Broderick A, DiGuglielmo M, Draijer LG, El-Matary W, Ferrari F, Furuya K, Gottrand F, Gupta N, Homan M, Jensen MK, Kamath BM, Kim KM, Kolho KL, Koot BG, Iorio R, Martinez M, Miloh T, Mohan P, Palle S, Papadopoulou A, Ricciuto A, Saubermann L, Sathya P, Shteyer E, Smolka V, Tanaka A, Varier R, Venkat V, Vitola B, Woynarowski M, Guthery S. Assessing the Validity of Adult-derived Prognostic models for PSC outcomes in children. J Pediatr Gastroenterol Nutr. 2020;70(1):12-17. PMID: 31651664
56. Kamath BM, Wen Y, Goodrich NP, Loomes KM, Romero R, Heubi JE, Leung DH, Spinner NB, Piccoli DA, Alonso EM, Guthery SL, Karpen SJ, Mack CL, Molleston JP, Murray KF, Rosenthal P, Squires JE, Teckman JH, Wang KS, Thompson RJ, Magee JC, Sokol RJ, the Childhood Liver Disease Research Network. Outcomes of Childhood Cholestasis in Alagille Syndrome: Results of a Multicenter Observational Study. Hepatol Commun. 2020;4(3):387-398.
57. Mack CL, Adams D, Assis DN, Kerkar N, Manns MP, Mayo MJ, Vierling JM, Alsawas M, Murad MH, Czaja AJ. Diagnosis and management of autoimmune hepatitis in adults and children: 2019 practice guidance and guidelines from the American Association for the Study of Liver Diseases. Hepatology 2020;72(2):671-722. PMID: 31863477
58. Kamath BM, Spino C, McLain R, Magee JC, Setchell KD, Miethke A, Molleston JP, Mack CL, Squires RH, Alonso EM, Murray KF, Loomes KM, Jensen MK, Karpen SJ, Rosenthal P, Thomas D, Sokol RJ, Shneider BL. Unraveling the Relationship between Itching, Scratch Scales, and Biomarkers in Children with Alagille Syndrome. Hepatol Comm 2020;4(7):1012-1018. PMID: 32626833 / PMCID: PMC7327199
59. Vierling JM, Kerkar N, Czaja AJ, Mack CL, Adams D, Assis D, Manns M, Mayo M, Nayfeh T, Majzoub AMMM, Alzuabi MA, Ding J, Haffar S, Murad MH, Alsawas M. Immunosuppressive Treatment Regimens in Autoimmune Hepatitis: Systematic Reviews and Meta-Analyses Supporting AASLD Guidelines. Hepatology 2020;72(2):753-769. PMID: 32500593
60. Feldman AG, Parsons JA, Dutmer CM, Veerapandiyan A, Hafberg E, Maloney N, Mack CL. Subacute Liver Failure Following Gene Replacement Therapy for Spinal Muscular Atrophy Type I. Jrl Pediatr 2020;225:252-258. PMID: 32473148
61. Azeltine MW, Chavez E, Nemec KM, Benarek JM, Asokan R, Balasubramaniyan N, Zgheib C, Mack CL, Roach JP. Inflammation Drives miRNAs to limit hepatocyte bile acid transport in biliary atresia. Jrl Surg Res 2020;256:663-72. PMID: 32818799
62. Venkat V, Ng VL, Magee JC, Wen Y, Hawthorne K, Harpavat S, Molleston JP, Murray KF, Wang KS, Soufi N, Bass LM, Alonso EM, Bezerra JA, Jensen MK, Kamath BM, Loomes KM, Mack CL, Rosenthal P, Shneider BL, Squires RH, Sokol RJ, Karpen SJ, Childhood Liver Disease Research Network. Modeling outcomes in children with biliary atresia with native liver after 2 years of age. Hepatol Comm 2020;4(12):1824-34.
63. Teckman J, Rosenthal P, Hawthorne K, Spino C, Bass LM, Murray KF, Kerkar N, Magee JC, Karpen S, Heubi JE, Molleston JP, Squires RH, Kamath BM, Guthery SL, Loomes KM, Sherker AH, Sokol RJ; ChiLDReN (Childhood Liver Disease Research Network, ... Mack, CL...). Longitudinal Outcomes in Young Patients with Alpha-1-Antitrypsin Deficiency with Native Liver Reveal that Neonatal Cholestasis is a Poor Predictor of Future Portal Hypertension. J Pediatr. 2020;227:81-86. PMID: 32663593
64. El-Matary W, Guthery SL, Amir AZ, DiGuglielmo M, Draijer LG, Furuya KN, Gupta N, Hochberg JT, Horslen S, Kerkar N, Koot BG, Laborda TJ, Loomes KM, Mack C, Martinez M, Miethke A, Miloh T, Mogul D, Mohammed S, Moroz S, Ovchinsky N, Perito ER, Rao G, Ricciuto A, Sathya P, Schwarz KB, Shah U, Singh R, Soufi N, Valentino PL, Zizzo A, Deneau MR. Colorectal Dysplasia and Cancer in Pediatric-onset Ulcerative Colitis Associated with Primary Sclerosing Cholangitis. Clin Gastroenterol Hepatol. 2021;19(5):1067-1070. PMID: 32360820
65. Deneau MR, Mack C, Perito ER, Ricciuto A, Valentino PL, Amin M, Amir AZ, Aumar M Auth M, Broderic A, et al. The Sclerosing Cholangitis Outcomes in Pediatrics (SCOPE) index: a prognostic tool for children. Hepatology 2021;73(3):1074-1087. PMID: 32464706
66. Luo Y, Brigham D, Bednarek J, Torres R, Wang D, Ahmad S, Mack CL. Unique cholangiocyte-targeted IgM autoantibodies correlate with poor outcomes in biliary atresia. Hepatology 2021;73(5):1855-1867. PMID: 32767570
67. Deneau MR, Mack C, Mogul D, Perito ER, Valentino PL, Amir AZ et al. Oral vancomycin, ursodeoxycholic acid or no therapy for pediatric primary sclerosing cholangitis: a matched analysis. Hepatology 2021;73(3):1061-1073. PMID: 32946600
68. Kemme S, Stahl M, Brigham D, Lovell MA, Nakano T, Feldman AG, Mack C. Outcomes of severe seronegative hepatitis-associated aplastic anemia: a pediatric case series. J Pediatr Gastroenterol Nutr 2021;72(2):194-201. PMID 32925550
69. Kemme S, Feldman AG, Mack C. Severe Seronegative Hepatitis-Associated Aplastic Anemia: Looking for the Best Treatment. J Pediatr Gastroenterol Nutr. 2021;73(2):e48. PMID: 34016886
70. Martinez M, Perito ER, Valentino P, Mack CL, Aumar M, Broderick A, Draijer LG, Fagundes EDT, Furuya KN, Gupta N, Horslen S, Jonas MM, Kamath BM, Kerkar N, Kim KM, Kolho KL, Koot BG, Laborda TJ, Lee CK, Loomes KM, Miloh T, Mogul D, Mohammed S, Ovchinsky N, Rao G, Ricciuto A, Schwarz KB, Smolka V, Tanaka A, Tessier MEM, Venkat VL, Vitola BE, Woynarowski M, Zerofsky M, Deneau MR. Recurrence of primary sclerosing cholangitis after liver transplant in children: an international observational study. Hepatology 2021;74(4):2047-2057. PMID: 34008252
71. Yoeli D, Choudhury RA, Sundaram SS, Mack CL, Roach JP, Karrer FM, Wachs ME, Adams MA. Primary versus salvage liver transplantation for biliary atresia: A retrospective cohort study. Jrl Ped Surg, accepted, Dec. 2021.
72. Luo Y, Bednarek J, Chaidez A, Atif S, Wang D, Mack CL. Regulatory T cell (Treg) CTLA-4 deficits in biliary atresia (BA) and disease rescue with Treg augmentation in murine BA. Gastro Hep Advances, in press, Dec. 2021.
73. Calinescu AM, Madadi-Sanjani O, Mack C, Schreiber RA, Kelly D, Petersen C, Wildhaber BE. Cholangitis definition and treatment after Kasai hepatoportoenterostomy for biliary atresia: a Delphi process and international expert panel. J Clin Med 2022;11:494.
74. Shneider, BL, Spino CA, Kamath BM, Magee JC, Ignacio RV, Huang S, Horslen SP, Molleston JP, Miethke aG, Kohli R, Leung DH, Jensen MK, Loomes KM, Karpen SJ, Mack C, et al. Impact of Long-term administration of Maralixibat on children with cholestasis secondary to Alagille syndrome. Hepatl Commun. Apr. 2022, in-press
75. Chaidez A, Pan Z, Sundaram SS, Boster J, Lovell M, Sokol RJ, Mack CL. The discriminatory ability of FibroScan liver stiffness measurement, controlled attenuation parameter and FibroScan-AST to predict severity of liver disease in children, Hepatol Commun, Accepted for publication 4/12/2022.

Books, Chapters, and Reviews
1. Sokol RJ and Mack CL, Etiopathogenesis of Biliary Atresia. Semin Liver Dis 2001; 21(4):517-24.
2. Sokol RJ, Mack CL, Narkewicz MR, Karrer FM. Pathogenesis and outcome of biliary atresia: current concepts, J Pediatr Gastroenterol Nut 2003;37(1):4-21.
3. Sokol RJ, Mack CL, Optimizing Outcomes and Bridging Biliary Atresia into Adulthood. Hepatology 2005;41(2):231-3. PMID: 15657917
4. Mack CL, Sokol RJ, Unraveling the Pathogenesis and Etiology of Biliary Atresia. Pediatr Res 2005;57(5 Pt 2):87R-94R. PMID: 15817506
5. Mack CL, Serum Cytokines as Biomarkers of Disease and Clues to Pathogenesis, Hepatology 2007;46(1):6-8. PMID: 17596866
6. Mack CL, The Pathogenesis of Biliary Atresia: Evidence for Virus-Induced Autoimmune Disease, Semin Liver Dis 2007;27(3):233-42. PMID: 17682970, PMCID: PMC3796656.
7. Lu BR and Mack CL. Inflammation and Biliary Tract Injury, Curr Opin Gastroenter 2009;25(3):260-264. PMID: 19396964
8. Brumbaugh D, Mack C. Conjugated hyperbilirubinemia in children. Pediatr Rev 2012;33(7):291-302. PMID: 22753787.
9. Feldman AG, Mack CL. Biliary atresia: cellular dynamics and immune dysregulation. Semin Pediatr Surg 2012;21(3):192-200. PMID: 22800972, PMCID: PMC3399127
10. Mack CL, Feldman AG, Sokol RJ. Clues to the etiology of bile duct injury in biliary atresia. Sem Liv Dis 2012;32(4):307-316. PMID: 23397531, PMCID: PMC3827890
11. Feldman A, Mack CL. Biliary Atresia: Clinical Lessons Learned. J Pediatr Gastroenterol Nutr 2015; 61(2):167-175. PMID 25658057
12. Mack CL. What Causes Biliary Atresia? Unique Aspects of the Neonatal Immune System Provide Clues to Disease Pathogenesis. Cell Mol Gastroenterol Hepatol 2015;1(3):267-274. PMID: 26090510
13. Cotter JM, Mack CL. Primary sclerosing cholangitis: Unique aspects of disease in children. Clin Liver Dis. 2017;10(5):120-123. PMID: 30992770
14. Kilgore A, Mack CL. Update on investigations pertaining to the pathogenesis of biliary atresia. Pediatr Surg Int 2017;33(12):1233-41. PMID: 29063959
15. Kamath B, Mack CL. From hepatocyte to cholangiocyte: the remarkable potential of transdifferentiation to treat cholestatic diseases. Hepatology. 2019;69(4):1828-1830. PMID 30179266
16. Goldberg A, Mack CL. Inherited cholestatic diseases in the era of personalized medicine. Clin Liver Dis 2020;15(3):105-109. PMID: 32257121; PMCID: PMC7128029
17. Karpen SJ, Kelly D, Mack C, Stein P. Ileal bile acid transporter inhibition as an anticholestatic therapeutic target in biliary atresia and other cholestatic disorders. Hepatol Int. 2020;14(5):677-89. PMID: 32653991
18. Kemme S, Mack CL. Pediatric Autoimmune Liver Diseases: Autoimmune Hepatitis & Primary Sclerosing Cholangitis. Pediatr Clin North Amer. 2021;68(6):1293-1307. PMID: 34736590
19. Corrado M, Mack CL. Diagnostic Tools for Early Detection of Biliary Atresia- is a Newborn Screen Attainable? Clin Liv Disease. 2022;19(1):25-28.
20. Boster J, Feldman A, Mack CL, Sokol RJ, Sundaram SS. Malnutrition in biliary atresia: Assessment, management and outcomes. Liv Transpl. 2021 Oct 20. Online ahead of print. DOI:10.002/lt.26339. PMID: 34669243
21. Sokol RJ, Mack CL. Biliary Atresia and the Ductal Plate. In: Murray KF and Larson AM (eds.), Fibrocystic Diseases of the Liver, Humana Press, New York. 2010:179-199.
22. Chambers B, Mack C. Neonatal hyperbilirubinemia. In: Bajaj L, Hambidge SJ, Kerby G and Nyquist A (eds.), Berman's Pediatric Decision Making, 5th Edition, Elsevier Mosby, PA. 2011:288-291.
23. Lu B, Mack C. Elevated liver tests after six months of age. In: Bajaj L, Hambidge SJ, Kerby G and Nyquist A (eds.), Berman's Pediatric Decision Making, 5th Edition, Elsevier Mosby, PA. 2011:234-237.
24. Lu B, Mack C. Infectious hepatitis. In: Bajaj L, Hambidge SJ, Kerby G and Nyquist A (eds.), Berman's Pediatric Decision Making, 5th Edition, Elsevier Mosby, PA. 2011:588-591.
25. Mack CL. Editor-Hepatology, Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition, 1st Edition, Castle, Connolly Publishing. 2011.
26. Kerkar N, Mack CL. Autoimmune hepatitis. In: Suchy FJ, Sokol RJ and Balistreri WF (eds.), Liver Disease in Children, 4th Edition, Lippincott Williams & Wilkins, PA. 2013.
27. Sokol RJ, Narkewicz MR, Sundaram SS, Mack CL. Chpt. 22 "Liver and Pancreas", In: Hay, Levin, Deterding and Abzug (eds.), CURRENT Diagnosis and Treatment Pediatrics, 23rd Edition, McGraw Hill Professional 2014.
28. Sundaram S, Mack CL. Abnormalities of Carbohydrate Metabolism and the Liver. Chpt. 73. In: Wylie and Hyams (eds.), Pediatric Gastrointestinal and Liver Disease, 5th Edition, Elsevier 2015.
29. Molla-Hosseini D, Mack CL. Pediatric PSC. Chpt. 3. In: Forman L. (ed.) Primary Sclerosing Cholangitis, 1st Edition, Springer 2016.
30. Boster J, Mack CL. Neonatal Cholestasis and Biliary Atresia. In: Encyclopedia of Gastroenterology, 2nd Edition, 2019.
31. Suchy FJ, Mack CL. Chpt. 62. Anatomy, Embryology, Developmental Anomalies and Pediatric Disorders of the Biliary Tract. In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease, 11th edition, Elsevier 2019.
32. Mack CL, Gourley G. Jaundice. Wylie and Hams (eds.), Chpt 16. In: Wylie and Hyams (eds.), Pediatric Gastrointestinal and Liver Disease, 6th Edition, Elsevier 2020.
33. Sundaram S, Mack CL. Abnormalities of Carbohydrate Metabolism and the Liver. Chpt. 73. In: Wylie and Hyams (eds.), Pediatric Gastrointestinal and Liver Disease, 6th Edition, Elsevier 2020.
34. Sokol RJ, Narkewicz MR, Mark JA, Mack CL, Feldman AG, Sundaram SS: Liver & Pancreas. In: Hay WW, Levin MJ, Deterding RR, Abzug MJ, (eds), Current Pediatric Diagnosis & Treatment, 25th edition McGraw-Hill Medical, NY NY, 2020.
35. Kerkar N, Mack CL. Autoimmune hepatitis. In: Suchy FJ, Sokol RJ, Balistreri WF, Shneider B, Mack CL and Bezerra J (eds.), Liver Disease in Children, 5th Edition, Lippincott Williams & Wilkins, PA. 2020.
36. Taylor S, Narkewicz M, Mack CL. Disorders of Iron Storage. In: Suchy FJ, Sokol RJ, Balistreri WF, Shneider B, Mack CL and Bezerra J (eds.), Liver Disease in Children, 5th Edition, Lippincott Williams & Wilkins, PA. 2020.

Editorials, Letters to Editor, Other
1. Mack CL. Introducing Ronald J. Sokol, MD- our 2018 AASLD president. Hepatology 2018;67(5):1669-1672. PMID: 29466842

Abstracts
1. C.L. Mack, P. Kavorik and K.M. Emerick, Early Speech Delay and Hepatitis as Presenting Signs of Homocystinuria, Poster Presentation, 1999 NASPGAN Meetings, Denver, Colorado.
2. *C.L. Mack, M. Abecassis, E.M. Alonso, P.F. Whitington, R.A. Superina, Urgent Living Related Liver Transplantation in Children with Fulminant Hepatic Failure or Acute Decompensated Cirrhosis, Poster Presentation at AST/ASTS Transplant 2000 Meetings, May, 2000, Chicago, Illinois and Oral Presentation at the International Liver Transplantation Society Meetings, June, 2000, Buenos Aires, Argentina.
3. C.L. Mack, M. Ferrario, M. Abecassis, P.F. Whitington, R.A. Superina, E.M. Alonso, Living Donor Liver Transplantation for Children in Liver Failure and Concurrent Multiple Organ System Failure, Poster Presentation at AASLD Annual Meetings, November, 2000, Dallas, TX.
4. *C.L. Mack, J. Lokar, F. Zelko, R.A. Superina, P.F. Whitington, Attention Span Deficits in Children with Extrahepatic Portal Vein Thrombosis, Oral Presentation, AGA, DDW Annual Meetings, May, 2001, Atlanta, Georgia.
5. C.L. Mack, D.A. Bambini, J. Lokar, P.F. Whitington, R.A. Superina, Coagulation Abnormalities in Pediatric Extrahepatic Portal Vein Thrombosis- Is REX Shunt the Cure? Poster Presentation, AASLD, DDW Annual Meetings, May, 2001, Atlanta, Georgia.
6. C.L. Mack, K.L. Neville and S.D. Miller, Role of Microglia as Antigen Presenting Cells and Effector Cells in Theiler's Murine Encephalomyelitis Virus-Induced Demyelination Disease, Poster Presentation, FASEB Autoimmunity Conference, June, 2001, Vermont.
7. *C.L. Mack, R.M. Tucker, B.L. Kotzin, R.J. Sokol, P.F. Whitington and S.D. Miller, Biliary Atresia is Associated with CD4+ Th1-Cell Mediated Portal Tract Inflammation, Oral Presentation, NASPGHAN, October, 2003, Montreal.
8. R.M. Tucker, R.J. Sokol, B.L. Kotzin and C.L. Mack, Immune Cell Mediated Biliary Destruction in a Murine Model of Biliary Atresia, Poster Presentation, NASPGHAN, October, 2003, Montreal.
9. *C.L. Mack, R.M. Tucker, R.J. Sokol, B.L. Kotzin, Validation of Rotavirus Murine Model of Biliary Atresia: Immune Mediated Bile Duct Injury, Oral Presentation, AASLD, October, 2004, Boston, MA.
10. J. Whitworth, R. Sokol, M. Narkkewicz, J. O'Connor, J. Haas, C. Mack, Acute Hepatitis and Acute Liver Failure Associated with Influenza A Infection, Poster Presentation, AASLD, October, 2004, Boston, MA.
11. *C. Mack, F. Zelko, R. Superina, A. Blei, P. Whitington, Minimal Portosystemic Encephalopathy is Reversed after Re-establishment of Portal Blood Flow in Children with Extrahepatic Portal Vein Thrombosis, Oral Presentation, AASLD, October, 2004, Boston, MA.
12. R.J. Hendrickson, R.M. Tucker, R.G. Gill and C.L. Mack, Progressive biliary destruction in the absence of a functional tumor necrosis factor pathway in murine biliary atresia, Poster Presentation, AASLD, November, 2005, San Francisco, CA.
13. *C.L. Mack, R.M. Tucker, R.G. Gill, Adoptive transfer of liver T cells from murine biliary atresia results in periductal infiltrates in recipient SCID mice suggesting autoimmune mediated bile duct injury, Oral Presentation, Plenary Session III- Basic Sciences, AASLD, November, 2005, San Francisco, CA.
14. B. Barnes, R.M. Tucker, C.L. Mack, The role of bile duct epithelia as antigen presenting cells in the murine model of biliary atresia, Poster Presentation, NASPGHAN Annual Meeting, 2006, Orlando, FL.
15. *C.L. Mack, M. Falta, A. Sullivan, F. Karrer, R.J. Sokol, A.P. Fontenot, Oligoclonal expansions of CD4+ and CD8+ T cells in patients with biliary atresia, Oral Presentation, Advances in Pediatric Hepatology, AASLD, October, 2006, Boston, MA.
16. R.M. Tucker, R.G. Gill and C.L. Mack, Generation of T-cell Hybridomas Specific for Bile Duct and Rhesus Rotavirus Antigens in a Murine Model of Biliary Atresia, Poster Presentation, American Association of Immunologists Annual Meeting, 2007, Miami Beach, FL.
17. *B.R. Lu, S. Brindley, R.M. Tucker, C. Lambert and C.L. Mack, Serum Autoantibodies Reactive to Cholangiocyte Cytosolic Proteins in Murine Biliary Atresia, Oral Presentation, Annual Digestive Diseases Weekly Meeting, 2008, San Diego, CA.
18. *B.R. Lu, S. Brindley, R.M. Tucker, C. Lambert and C.L. Mack, Serum Autoantibodies Reactive to Alpha-Enolase and Vimentin in Murine and Human Biliary Atresia, Oral Presentation, Advances in Pediatric Hepatology, AASLD, October, 2008, San Francisco, CA.
19. F. Wehrmann, B.R. Lu, R.M. Tucker and C.L. Mack, Generation of B-cell Hybridomas Producing Antibodies Reactive to Bile Duct Epithelial Proteins in Murine BA, Poster Presentation, Autoimmune Liver Diseases, AASLD, October, 2008, San Francisco, CA.
20. *R.M. Tucker, S.M. Brindley, C.L. Mack, Regulatory T cell Dysfunction in Murine Biliary Atresia, Oral Presentation, Pediatric Hepatology: Translational Research, AASLD, November, 2010, Boston, MA.
21. C.L. Mack, F. Karrer, S. Brindley, A. Martin, A.P. Fontenot, Liver T cell Activation and IFN-g production in response to CMV peptides in Biliary Atresia Patients at the Time of Diagnosis, Poster Presentation, Pediatric Hepatology, AASLD, November, 2010, Boston, MA.
22. A. Feldman, R. Tucker, R. Pelanda, C. L. Mack, Critical Role of B Cells in the Development of Bile Duct Injury and Obstruction in Murine Biliary Atresia, Poster Presentation, Pediatric Hepatology, AASLD, November, 2011, San Francisco, CA.
23. C.L. Mack, K. Anderson, MT. Aubrey, R.J. Sokol, B.M. Freed, Lack of HLA Predominance and HLA Shared Epitopes in Biliary Atresia, Poster Presentation, Pediatric Hepatology, AASLD, November, 2012, Boston, MA.
24. *E.K. Peiffer, J. Boguniewicz, R.M. Tucker, R.J. Sokol, C.L. Mack, High Dose IgG Therapy in Murine Biliary Atresia Results in Decreased Bile Duct Injury Through Expansion of Regulatory T Cells and Inhibition of CD4 Th1 Cytokine Production, Oral Presentation, Experimental and Translational Research in Pediatric Hepatology, AASLD, November, 2012, Boston, MA.
25. *J. Boguniewicz, E.K. Peiffer, R.M. Tucker, R.J. Sokol, C.L. Mack, High Dose IgG Therapy in Murine Biliary Atresia Protects From Bile Duct Injury, Oral Presentation, NASPGHAN Annual Meeting, 2012, Salt Lake City, UT.
26. M. Boruta, C.L. Mack, and R.J. Sokol. Neonatal Acute Liver Failure as a Presentation of Congenital Hemophagocytic Lymphohistiocytosis, Poster Presentation, NASPGHAN Annual Meeting, 2013, Chicago, IL.
27. S. Fernando, C.Mack, F. Karrer, D. Dovel, and S. Sundaram. Hepatic arteriovenolymphatic malformation masquerading as severe pulmonary hypertension and high output cardiac failure. Poster presentation, NASPGHAN Annual Meeting, 2013, Chicago, IL.
28. K.S. Wang, B.L. Shneider, C. Azen, R. Arnon, L. Bass, M.A. Bozic, M.L. Brandt, M. Clifton, P.A. Dillon, A. Fecteau, S.J. Karpen, C.L. Mack, et al. Analysis of surgical interruption of the enterohepatic circulation as a treatment for pediatric cholestasis: a retrospective, multi-institutional study, Poster presentation, AASLD, 2014, Boston, MA.
29. B. Traxinger, J. Roach, D. Molla Hosseini, R. Pelanda, A. Rengasamy, C.L. Mack. B cell activation in the rotavirus-induced mouse model of biliary atresia, Poster presentation, 16th Annual Colorado Immunology Conference, Department of Immunology & Microbiology, University of CO Anschutz Medical Campus, 2015, Vail, CO.
30. B. Traxinger, J. Roach, D. Molla Hosseini, R. Pelanda, A. Rengasamy, C.L. Mack. The Role of B Cells as Antigen Presenting Cells and Immune Activators in a Mouse Model of Biliary Atresia, Poster presentation, AASLD, 2015, San Francisco, CA.
31. R. Asokan, K. El Kasmi, B. Traxinger, J. Roach, B. Natarajavelalar and C.L. Mack. The Rotavirus Induced Mouse Model of Biliary Atresia is Associated with Down Regulation of Bile Acid Transporters that are Restored in B cell Deficient Mice, Poster presentation, AASLD, 2015, San Francisco, CA.
32. M.A. Sheiko, S.S. Sundaram, K.E. Capocelli, P. Zhaoxing, A.M. McCoy, C.L. Mack. The Natural History of Autoimmune Hepatitis and Corresponding Azathioprine Dosing in Children, Poster presentation, AASLD, 2015, San Francisco, CA.
33. M.A. Sheiko, S. Giugliano, C. Waasdorp-Hurtado, MD, C.L. Mack, M. Narkewicz, H.R. Rosen, L. Golden. CD4+ helper T Cell Activation in Children with Hepatitis C, Poster presentation, AASLD, 2015, San Francisco, CA.
34. J. Mark, C.L. Mack, R. Kramer, Outcomes of metallic biliary stent placement in children, Poster presentation, NASPGHAN World Congress, 2016, Montreal, Canada.
35. *M.R. Deneau, W. El-Matary, R. Varier, A, Konidari, T.A. Miloh, E. Shteyer, O. Ledder, R. Abdou, B. Vitola, M. Homan, A. Papadopoulou, K.N. Furuya, ...C. Mack et.al. Natural history of primary sclerosing cholangitis in 500 children: data from the Pediatric PSC Consortium, Oral presentation, AASLD, 2016, Boston, MA.
36. *M.R. Deneau, W. El-Matary, R. Varier, A, Konidari, T.A. Miloh, E. Shteyer, O. Ledder, R. Abdou, B. Vitola, M. Homan, A. Papadopoulou, K.N. Furuya, ...C. Mack et.al. Ursodeoxycholic acid treatment does not improve liver outcomes in pediatric PSC: a multicenter, international collaboration, Oral presentation, AASLD, 2016, Boston, MA.
37. M.R. Deneau, W. El-Matary, R. Varier, A, Konidari, T.A. Miloh, E. Shteyer, O. Ledder, R. Abdou, B. Vitola, M. Homan, A. Papadopoulou, K.N. Furuya, ...C. Mack et.al. Laboratory predictors of longterm prognosis in primary sclerosing cholangitis: data from the pediatric PSC consortium, Poster presentation, AASLD, 2016, Boston, MA.
38. M.R. Deneau, W. El-Matary, R. Varier, A, Konidari, T.A. Miloh, E. Shteyer, O. Ledder, R. Abdou, B. Vitola, M. Homan, A. Papadopoulou, K.N. Furuya, ...C. Mack et.al. Primary sclerosing cholangitis and autoimmune sclerosing cholangitis are associated with similar outcomes: data from the pediatric PSC consortium, Poster presentation, AASLD, 2016, Boston, MA.
39. J. Bednarek, B. Traxinger, D. Molla-Hosseini, R. Pelanda, C. Mack. B cell mechanisms of T cell activation in the murine model of biliary atresia. Poster presentation, AASLD, 2016, Boston, MA.
40. *R.J. Sokol, C. Spino, J. Moore, J.A. Bezerra, P.F. Whitington, S.J. Karpen, K.M. Loomes, V.L. Ng, V.L. Venkat, K.S. Wang, C.J. Goodhue, A.H. Sherker, J.C. Magee, C.L. Mack. Intravenous Immunoglobulin following portoenterostomy in biliary atresia: a phase 1/2A trial, Oral presentation, Late Breaking Abstract, AASLD, 2016, Boston, MA.
41. J. Mark, C. Mack, R. Kramer. Use of Self Expanding Metal Biliary Stents at a Pediatric Center, a Case Series, Poster presentation, World Congress of Pediatric Gastroenterology Hepatology and Nutrition, 2016, Montreal, Canada.
42. J.M. Cotter, L.P Browne, K.E. Capocelli, A. McCoy, C.L. Mack. Pediatric PSC: Moderate liver fibrosis, mild strictures and lack of biomarker correlation. CHCO Department of Pediatrics Research Poster Session, May, 2017, Aurora, CO.
43. D. Molla Hosseini, R. Howison, Q.Z. Li, C.L. Mack. Identification of autoantibodies in biliary atresia: autoantigen microarray technology. Poster presentation, Biliary Atresia: A Clinical and Translational Science Research Workshop, NIH, June 2017, Bethesda, MD.
44. J. Bednarek, B. Traxinger, D. Molla Hossieni, R. Pelanda, C.L. Mack. Dual Role of B cells in the T cell-mediated bile duct injury of murine biliary atresia. Poster presentation, Biliary Atresia: A Clinical and Translational Science Research Workshop, NIH, June 2017, Bethesda, MD.
45. S. Kim, J. Moore, R.J. Sokol, C. Spino, J. Moore, J.A. Bezerra, P.F. Whitington, S.J. Karpen, K.M. Loomes, V.L. Ng, V.L. Venkat, K.S. Wang, C.J. Goodhue, A.H. Sherker, J.C. Magee, and C.L. Mack. Correlation of immune markers with short-term outcomes in biliary atresia following IVIg treatment. Poster presentation, AASLD, October 2017, Washington D.C.
46. S. Kim, J. Moore, R.J. Sokol, C. Spino, J. Moore, J.A. Bezerra, P.F. Whitington, S.J. Karpen, K.M. Loomes, V.L. Ng, V.L. Venkat, K.S. Wang, C.J. Goodhue, A.H. Sherker, J.C. Magee, and C.L. Mack. Correlation of immune markers with short-term outcomes in biliary atresia following IVIg treatment. Poster presentation, NASPGHAN, Nov. 2017, Las Vegas, NV.
47. *B. Shneider, ... C.L. Mack et al. Results of ITCH, A Multi-center Randomized Double-blind Placebo-controlled Trial of Maralixibat, an Ileal Apical Sodium-dependent Bile Acid Transporter Inhibitor (ASBTi), for Pruritus in Alagille Syndrome (ALGS). Oral presentations, AASLD, 2017, Washington D.C. and NASPGHAN, 2017, Las Vegas
48. B. Kamath, ... C.L. Mack et al. Unraveling the Relationship between Itching, Scratch Scales and Biomarkers in Children with Alagille Syndrome. Poster presentation, AASLD, 2017, Washington D.C.
49. *R. Thompson, ... C.L. Mack, et al. Phase 2 open-label efficacy and safety study of the apical sodium-dependent bile acid transporter inhibitor maralixibat in children with progressive familial intrahepatic cholestasis: 48-week interim efficacy analysis. Oral presentation, AASLD, 2017, Washington D.C.
50. *M. Deneau, ... C. Mack et al. Improvement in GGT predicts event-free survival in primary sclerosing cholangitis regardless of ursodeoxycholic acid treatment: data from the Pediatric PSC Consortium. Oral presentation, AASLD, 2017, Washington D.C.
51. M. Deneau, ... C. Mack et al. Validating the Mayo model of primary sclerosing cholangitis outcomes in children: data from the Pediatric PSC Consortium. Poster presentation, AASLD, 2017, Washington D.C.
52. D.D. Black, C.L. Mack, N. Kerkar, et al. Initial results of the WUPPSC study- prospective multicenter withdrawal of UDCA in pediatric PSC. Poster presentation, DDW, 2018, Washington D.C.
53. M. Deneau, ... C.L. Mack, et al. Variability in Diagnostic and Therapeutic Strategies for Pediatric Primary Sclerosing Cholangitis between Centers in the Pediatric PSC Consortium, Poster presentation, AASLD, 2018, San Francisco, CA
54. *M. Deneau, .... C.L. Mack, et al. Clinical Outcomes of Oral Vancomycin Therapy for Children with Primary Sclerosing Cholangitis in the Pediatric PSC Consortium, Oral presentation, AASLD, 2018, San Francisco, CA
55. M. Bannerman, C.L. Mack, et al. Inflammation Drives microRNA Expression to Limit Hepatocyte Bile Acid Synthesis and Transport in the Biliary Atresia Mouse Model, Poster presentation, *Poster of Distinction, AASLD, 2018, San Francisco, CA
56. *V. Venkat,... C.L. Mack, et al. Predictors of Outcome in Children with Biliary Atresia Surviving with Native Liver at Two Years of Age, Oral presentation, AASLD, 2018, San Francisco, CA
57. *D.D. Black, C.L. Mack, N. Kerkar, et al. Results of the WUPPSC study: prospective multicenter withdrawal of ursodeoxycholic acid in pediatric primary sclerosing cholangitis, Oral presentation, NASPGHAN, 2018, Hollywood, FL.
58. *R. Thompson, D. Kelly, S. Rajwal, A. Miethke, N. Soufi, C. Rivet, I. Jankowska, C. Mack, T. Jaeckin, R.H. Squires, K.M. Loomes. Growth analysis in children with PFIC treated with the ASBT inhibitor maralixibat. Oral presentation, EASL International Liver Congress, 2019, Vienna, Austria.
59. Y. Luo, D. Brigham, J. Bednarek, R. Torres, C. Mack. Cholangiocyte-specific IgM autoantibodies correlate with poor outcome in biliary atresia. *Poster presentation with Distinction, AASLD Annual Meeting, 2019, Boston, MA.
60. M. Martinez,... C. Mack... M. Deneau. Primary sclerosing cholangitis immune reactivity pre-transplant is a predictor of recurrent disease after liver transplantation. Oral presentation, AASLD Annual Meeting, 2019, Boston, MA.
61. J. Bednarek, Y. Luo, R. Torres, C.L. Mack. Biliary atresia is associated with regulatory T cell abnormalities and Treg enhancer therapy attenuates disease in murine BA. Oral presentation, AASLD Annual Meeting, 2019, Boston, MA.
62. K. Loomes,... C. Mack... R. Thompson. Genotype and dose-dependent response to maralixibat in patients with bile salt export pump deficiency. Oral presentation, AASLD Annual Meeting, 2019, Boston, MA.
63. Kemme, S, Brigham D, Feldman A, Stahl M, Nakano T, Mack C. Immunosuppressive Therapy and Outcomes of Severe Seronegative Immune-Mediated Hepatitis and Aplastic Anemia. Poster presentation, NASPGHAN Annual Meeting. 2019, Chicago, IL.
64. K. Loomes,... C. Mack... R. Thompson. Analysis from Phase 2 INDIGO study demonstrates transplant-free survival for pediatric patients with PFIC2. Late-breaking abstract oral presentation, Digital International Liver Congress (EASL), August 2020.
65. J. Hochberg, ...C. L. Mack..., M. Deneau. Pediatric PSC is Associated with Poor Outcomes in Racial/Ethnic Minorities. Poster Presentation, AASLD The Liver Meeting, November 2020, Virtual.
66. B.L. Shneider,.... C.L. Mack, ...R.J. Sokol. Preliminary Analysis of ITCH and IMAGINE II- Outcome of Long Term Administration of Maralixibat in Children with Alagille Syndrome. Oral Presentation, AASLD The Liver Meeting, November 2020, Virtual.
67. D. Yoeli, Z. Wang, Y. Luo, A. Chaidez, M. Adams, C. Huang, C. Mack, N. Alvarez. Galectin-3 levels in clinical and murine models of pediatric cholestatic liver disease. American Society for Transplantation Annual Meeting 2021, Virtual.
68. *R.J. Thompson, H.J. Verkade, E. Gonzalès, S. Karpen, C. Mack, K. Loomes, L. Kjems, P. Horn, Long-term Treatment Benefits of Odevixibat, an Ileal Bile Acid Transporter Inhibitor, in Children With Progressive Familial Intrahepatic Cholestasis: Secondary and Exploratory Efficacy Outcomes During the Phase 3 PEDFIC 1 and PEDFIC 2 Studies, Oral Presentation, 6th World Congress of Pediatric Gastroenterology, Hepatology and Nutrition, June 2021, Virtual.
69. *Y. Luo, A. Chaidez, C. Shearn, A. McKee, C.L. Mack. Neutrophil Activation in Biliary Atresia. Oral presentation. Childhood Liver Disease Research Network Scientific Meeting, September 2021, Virtual.
70. *Y. Luo, A. Chaidez, C. Shearn, A. McKee, C.L. Mack. Neutrophil Activation in Biliary Atresia. Poster presentation- Chosen presentation for Pediatric Liver Disorders Special Interest Group Poster Debrief Session. AASLD- The Liver Meeting, November 2021, Virtual.
71. D. Yoeli, Y. Luo, A. Chaidez, Z. Wang, M.A. Adams, C.A. Huang, C.L. Mack, N. Navarro-Alvarez. Galectin-3 as a biomarker and potential therapeutic target in biliary atresia. Poster presentation. AASLD- The Liver Meeting, November 2021, Virtual.
72. *A. Chaidez, M. Lovell, Z. Pan, K. Rivas, J. Boster, R. Sokol, S. Sundaram, C. Mack. FibroScan correlates with ISHAK fibrosis stage in pediatric liver disease and FibroScan-AST predicts severity of pediatric NAFLD. Oral presentation- Pediatric Hepatology: Metabolic and Genetic Diseases. Parallel Session. AASLD- The Liver Meeting, November 2021, Virtual.
73. M.R. Deneau, J.P. Stevens, E.R. Perito,... C.L. Mack, et al. and the Pediatric PSC Consortium. Immunosuppression did not alter outcomes in pediatric PSC with AIH overlap. Poster presentation. AASLD- The Liver Meeting, November 2021, Virtual.
74. J. Stevens, N. Gupta, ... C. Mack, et al. and the Pediatric PSC Consortium. The role of liver biopsy in the diagnosis and prognosis of pediatric PSC and autoimmune hepatitis overlap. Poster presentation. AASLD- The Liver Meeting, November 2021, Virtual.
75. S. Taylor, S. Harpavat, K.D. Gromer, S.J. Karpen, E. M. Alonso, C.L. Mack, Serum levels of 3 cytokines in BA at the time of Kasai portoenterostomy are associated with future outcomes. Poster presentation. AASLD- The Liver Meeting, November 2021, Virtual.
76. *E. Gonzales,... C.Mack, et al. Relationships between changes in autotaxin, pruritus, and serum bile acids after odevixibat treatment in patients with PFIC: data from a pooled analysis. Oral presentation- Pediatric Hepatology: Metabolic and Genetic Diseases Parallel Session. AASLD- The Liver Meeting, November 2021, Virtual.
77. *S. Khushal, ... C. Mack et al. and the Pediatric PSC Consortium. IBD after liver transplantation in children with PSC. Oral presentation- Clinical/ Translational Research in Pediatric Hepatology Parallel Session. AASLD- The Liver Meeting, November 2021, Virtual.

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