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CURRICULUM VITAE

David S. Marks MD
Vice Chair, Professor
Department of Medicine
Division of Cardiology

OFFICE ADDRESS:
The Hub for Collaborative Medicine
8701 Watertown Plank Road
Milwaukee, WI 53226

EDUCATION:
1984 - 1985 Teaching Assistant, Human Biology Core, Stanford University, Stanford
1985 - Present AB Stanford University, Stanford, CA (with distinction)
1989 - Present MD University of California, San Francisco, CA
2000 - Present Faculty Development Training Course, Medical College of Wisconsin, Milwaukee, WI
2004 - Present MBA Kellogg School of Management, Northwestern University, Chicago, IL

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
1989 - 1992 Assistant in Medicine, Brigham and Woman's Hospital, Boston, MA
1989 - 1990 Intern and Resident in Medicine, Brigham and Woman's Hospital, Boston, MA
1989 - 1995 Clinical and Research Fellow in Medicine and Cardiology, Harvard Medical School, Boston, MA
1994 - 1995 Interventional Cardiology Fellowship, Brigham and Women's Hospital, Boston, MA
1995 - 1996 Resident in Internal Medicine, Mayo Clinic, Rochester, MN
1995 - 1996 Advanced Interventional Cardiology Fellowship, Mayo Clinic, Rochester, MN
2000 - Present Advanced Peripheral Vascular Fellowship, Linder Center for Research and Education/ Christ Hospital, Cincinnati, OH

FACULTY APPOINTMENTS:
1984 - 1985 Teaching Assistant, Human Biology Core, Stanford University, Stanford, CA
1996 - 2000 Assistant Professor of Medicine, Medical College of Georgia, Augusta, GA
2000 Associate Professor of Medicine, Medical College of Georgia, Augusta, GA
2000 - 2007 Associate Professor of Medicine, Medical College of Wisconsin
2007 - 2011 Associate Professor of Medicine, Cardiovascular Medicine and Radiology, Medical College of Wisconsin, Milwaukee, WI
2011 - Present Professor of Medicine, Cardiovascular Medicine and Radiology, Medical College of Wisconsin, Milwaukee, WI

ADMINISTRATIVE APPOINTMENTS:
2006 - 2008 Director of Special Projects, Medical College Physicians, Medical College of Wisconsin, Milwaukee, WI
2008 - Present Vice Chair Clinical Programs, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
2018 - Present Department of Medicine, Interim Division Chief of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI

HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:
1996 - 2000 Physician, Augusta VA Medical Center, Augusta, GA
1996 - 2000 Physician, Medical College of Georgia Hospitals and Clinics, Augusta, GA
1996 - 2000 Director, Cardiac Catheterization Laboratories, Medical College of Georgia, Augusta, GA
2000 - Present Physician and Director, Cardiac Catheterization Laboratories, Froedtert Memorial Lutheran Hospital, Milwaukee, WI
2000 - Present Physician, Clement J. Zablocki Veterans Affairs Medical Center
2011 - Present Senior Medical Director, Inpatient Service, Froedtert Hospital, Milwaukee, WI
Milwaukee, WI

RESEARCH ADMINISTRATIVE APPOINTMENTS:
2001 - 2015 Director, Clinical Trials, Medical College of, Division of Cardiology
2006 - 2013 Member, Board of Directors (Secretary 2009 - 2013), INRange Systems, Inc., Altoona, PA
2006 - 2010 Chief Medical Officer, Viacor, Inc., Wilmington, MA

HOSPITAL STAFF PRIVILEGES:
1996 - 2000 Medical College of Georgia Health Hospital, Augusta, GA
1996 - 2000 Norwood Veterans Administration Hospital, Augusta, GA
2000 - Present Froedtert Hospital, Milwaukee, WI
2000 - Present Zablocki Veterans Administration Hospital, Milwaukee, WI
2004 - 2006 Community Memorial Hospital, Menomonee Falls, WI
2010 - Present St. Joseph's Hospital, West Bend, WI

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
American Board of Internal Medicine
09/16/1992
12/31/2022
Subspecialty Board of Cardiovascular Disease 11/10/1995 12/31/2015 Subspecialty Certification in Interventional
11/31/1999
12/31/2025
Cardiology
None
Meeting maintenance of certification requirements.
None
   
Licensure
Number Issue DateExpiration
Massachusetts
#74728
1989
None
Minnesota
#38247
09/16/1995
None
Georgia
#0118-2
1999
None
Wisconsin #
42189-020
06/06/2000
None
Ohio
#35-07-8175-M
06/29/2000
None
DEA
#BM2950992
12/03/2015
01/3120
    

AWARDS AND HONORS:
1984 American Heart Association Summer Research Award
2009 Medical College of Wisconsin Outstanding Faculty Service Recognition
2017 Faculty Vitality Award , Medical College of Wisconsin
2017 Lee Biblo, MD Excellence in Professionalism Award, Medical College Physicians, Medical College of Wisconsin

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
1995 - Present American College of Cardiology (Fellow)
2001 - Present Society for Cardiac Angiography & Interventions (Fellow)
2008 - Present Society of Cardiovascular Computed Tomography (Physician/Scientist Member)
2010 - Present American College of Physicians (Fellow)
2016 - Present Cardiovascular Center, Medical College of Wisconsin (Primary member)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Ad-Hoc Reviewer
1998 - Present Abstract referee, Journal of the American College of Cardiology
1999 - 2001 Manuscript review, American Heart Journal
2001 - 2006 Manuscript review, American Journal of Physiology
2003 - 2006 Abstract referee, American Heart Association Annual Scientific Meeting

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2000 - 2001 Medical Director, Wisconsin Society of Cath Lab Professionals

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2000 - 2002 Chairman, Cardiology Advisor Board, Novation Corporation
2005 - Present Member, Cardiovascular Council Steering Committee, University Health Systems/Vizient

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
RESPECT. IDE#: G990318. Randomized Evaluation of Recurrent Stroke comparing PFO Closure to Established Current Standard of Care Treatment
Source:
AGA, Inc. (ClinicalTrials.gov Identifier: NCT00465270)
Role & Effort:
Principal investigator
Dates:
2003 - Present
  
Title:
“PFO ACCESS Registry: Patent Foramen Ovale Closure with the Amplatzer PFO Occluder in Patients with recurrent Cryptogenic Stroke due to Presumed Paradoxical Embolism through a Patent Foramen Ovale who have Failed Conventional Drug therapy.” (ClinicalTrials.gov Identifier: NCT00583401)
Source:
AGA Medical, LLC
Role & Effort:
Sub-Investigator
Dates:
2007 - Present
  
Title:
“Interagency Registry of Mechanical Assisted Circulatory Support.” (INTERMACS) (ClinicalTrials.gov Identifier: NCT00119834)
Source:
NHLBI
Role & Effort:
Sub-Investigator
Dates:
2011 - Present
  
Title:
“GORE HELEX™ Septal Occluder / GORE® Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke or Imaging- Confirmed TIA in Patients with Patent Foramen Ovale (PFO). Study Protocol Number: HLX 06-03. (REDUCE)”. (ClinicalTrials.gov Identifier: NCT00738894)
Source:
W.L.Gore & Associates, Inc.
Role & Effort:
Principal-Investigator
Dates:
2012 - Present
  
Title:
“Samurai Clinical Study ImageReady™ MR Conditional Pacing System.” (SAMURAI) (ClinicalTrials.gov Identifier: NCT01781078)
Source:
Boston Scientific
Role & Effort:
Sub-Investigator
Dates:
2013 - Present
  
Title:
AACVPR Registry. The American Association of Cardiovascular and Pulmonary Rehabilatation (AACVPR) Outpatient Cardiac Rehabilitation registry.
Source:
None
Role & Effort:
Sub-Investigator
Dates:
2013 - Present
  
Title:
Measurement of NonInvasive Blood Pressure in Neonates Through Adults and Special Populations (MISSION) (ClinicalTrials.gov Identifier: NCT02125331)
Source:
GE Healthcare
Role & Effort:
Principal Investigator
PI:
Dates:
2014 - Present
  
Title:
A Phase II, Randomized, Double-Blind, Multicenter, Multinational, Placebo-Controlled, Parallel-Groups Study to Evaluate the Safety and Efficacy of Intramuscular Injections of Allogeneic PLX-PAD Cells for the Treatment of Subjects with Intermittent Claudication (IC). PLX-PAD 1204-01.” (ClinicalTrials.gov Identifier: NCT01679990)
Source:
Pluristem Ltd
Role & Effort:
Sub-Investigator
Dates:
2015 - Present
  
Title:
Targeted, Highly Sensitive, Non-Invasive Cardiac Transplant Rejection Monitoring.” (ClinicalTrials.gov Identifier: NCT 02109575)
Source:
NHLBI
Role & Effort:
Sub-Investigator
Dates:
2015 - Present
  
Title:
Medtronic AdaptResponse Study.” (ClinicalTrials.gov Identifier: NCT02205359)
Source:
Medtronic, Inc.
Role & Effort:
Sub-Investigator
Dates:
2015 - Present
  
Title:
“A Phase IIB Randomized Double-Blind, Placebo Controlled - Study to Evaluate the Safety and Efficacy of JVS-100 Administered by Direct Intramuscular Injection as adjunct to revascularization of infrapopliteal lesions in subjects with advanced Peripheral Artery Disease (PAD) and tissue loss (ulceration and/or gangrene).”STOP-PAD. JTCS-007.” (ClinicalTrials.gov Identifier: NCT02544204)
Source:
Juventas
Role & Effort:
Sub-Investigator
Dates:
2016 - Present
  
Title:
A Phase 2/3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of GS 6615 on Exercise Capacity in Subjects with Symptomatic Hypertrophic Cardiomyopathy. GS-US-361-1157.” (ClinicalTrials.gov Identifier: NCT02291237)
Source:
Gilead Sciences, Inc.
Role & Effort:
Sub-Investigator
Dates:
2016 - Present
  
Title:
LAAO Registry. American College of Cardiology Foundation Left Atrial Appendage Occlusion Registry.
Source:
None
Role & Effort:
Principal-Investigator
Dates:
2016 - Present
  
Prior
Peer Review
Title:
Treat angina with Aggrastat and Determine the cost of therapy with invasive or conservative strategy (TIMI 18)
Source:
Merck and Company
Role & Effort:
Principal investigator
Dates:
1998 - 2000
  
Title:
Prevention of restenosis by Tranilast and its Outcomes (PRESTO): A phase III double-blind, placebo controlled trial of three doses of Tranilast
Source:
Bristol-Myers Squibb and Sanofi Research
Role & Effort:
Principal investigator
Dates:
1999 - 2000
  
Title:
(The OPERA Trial): “Omapatrilat in persons with enhanced riskof atheroscerotic events.”
Source:
Bristol-Myers Squibb
Role & Effort:
Principal investigator
Dates:
2000 - 2001
  
Title:
“Multi-center InSync™ Randomized Clinical Evaluation.”
Source:
Medtronic
Role & Effort:
Sub-investigator
Dates:
2000 - 2001
  
Title:
“InSyncIII / Attain OTW Trial.”
Source:
Medtronic, Inc.
Role & Effort:
Sub-investigator
Dates:
2001 - 2003
  
Title:
(REPLACE-2) Randomized Evaluation in PCI Linking Angiomax to Reduced Clinical Events
Source:
The Medicines Co.
Role & Effort:
Principal investigator
Dates:
2001 - 2003
  
Title:
(A-HeFT): The African American Heart Failure Trial.
Source:
Nitromed, Inc., and The Association of Black Cardiologists, Inc (ABC)
Role & Effort:
Sub-investigator
Dates:
2001 - 2004
  
Title:
A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate Pharmacokinetics and Pharmacodynamics of a 6 Hour or 24 Hour Levosimendan Infusion in Subjects with New York Heart Association Class III/IV Congestive Heart Failure.
Source:
Abbott Laboratories
Role & Effort:
Sub investigator
Dates:
2002 - 2003
  
Title:
Oasis-5: An International, Randomized, Double- Blind Study Evaluating the Efficacy and Safety of Fondaparinux versus Enoxaparin in the Acute Treatment of Unstable Angina / Non ST-Segment Elevation MI Acute Coronary Syndromes.
Source:
Sanofi Synthelabo
Role & Effort:
Sub-investigator
Dates:
2003 - 2005
  
Title:
PERISCOPE: A Double-Blind, Randomized Comparator-Controlled Study in Subjects with Type II Diabetus Mellitus Comparing the Effects of Pioglitazone HVL versus Glimepiride on the Rate of Progression of Atherosclerotic Disease as Measured by Intravascular Ultrasound.
Source:
Takeda Pharmacutical North America, Inc.
Role & Effort:
Sub-investigator
Dates:
2003 - 2005
  
Title:
LUNAR: A 12-week, Randomized, Open-Label, 3-Arm, Parallel Group, Multicenter, Phase IIIb Study Comparing the Efficacy and Safety of Rosuvastatin 20 mg and 40 mg with that of Atorvastatin 80 mg in Subjects with Acute Coronary Syndromes.
Source:
AstraZeneca
Role & Effort:
Sub-investigator
Dates:
2004 - 2005
  
Title:
“Clinical Applicability, Correlation, and Modeling of Cardiac CT”.
Source:
GEHC, Investigator Initiated Trial
Role & Effort:
Principal investigator
Dates:
2004 - 2016
  
Title:
STEEPLE: An International Phase 2-3, Stratified, Randomized, Open-label, Parallel-group Clinical Trial to Evaluate the Safety and Efficacy of a Single Intravenous Bolus of Enoxaparin Versus Intravenous Unfractionated Heparin in Patients Undergoing Non-emergent Percutaneous Coronary Intervention.
Source:
Stanofi-Aventis
Role & Effort:
Principal investigator
Dates:
2004 - 2005
  
Title:
SEPIA-PCI: A multinational, randomized, double-blind, double-dummy, exploratory, parallel-group, dose-ranging phase II Study to Evaluate the Pharmacodynamics, the safety and tolerability, and the pharmacokinetics of several Intravenous regimens of the factor Xa inhibitor otamixAban (XRP0673), in comparison to intravenous unfractionated heparin, in subjects undergoing non-urgent Percutaneous Coronary Intervention.
Source:
Sanofi-Aventis
Role & Effort:
Principal Investigator
Dates:
2004 - 2006
  
Title:
APEX-AMI: (Assessment of PEXelizumab in Acute Myocardial Infarction). A Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study of Pexelizumab in Patients with Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.
Source:
Alexion Clinical Research Studies
Role & Effort:
Sub-investigator
Dates:
2004 - 2005
  
Title:
PREMIUM: A Randomized Blinded Trial to Evaluate the Efficacy of Percutaneous Closure of Patent Foramen Ovale in Severe Intractable Migraine
Source:
AGA, Inc. (ClinicalTrials.gov Identifier: NCT00355056)
Role & Effort:
Principal Investigator
Dates:
2007 - 2015
  
Title:
IMPEDE-HF: A Prospective, Non-randomized, Longitudinal Study to Determine if Thoracic Impedance When Measured by the Optivol® Algorithm Provides Diagnostic Predictive Value in Management of Congestive Heart Failure.
Source:
Medtronic
Role & Effort:
Sub-investigator
Dates:
2007 - 2011
  
Title:
TAMARIS: A Randomized, Double-blind, Placebo-controlled Parallel Group Study of the Efficacy and Safety of 4 administrations of XRP0038/NV1FGF 4mg at 2 Week Intervals on Amputation or Any Death in Critical Limb Ischemia Patients With Skin Lesions. (ClinicalTrials.gov Identifier: NCT00566657)
Source:
Sanofi Aventis
Role & Effort:
Sub-investigator
Dates:
2008 - 2012
  
Title:
DETECT AC-052-510: A two-stage prospective observational cohort study in scleroderma patients to evaluate screening tests and the incidence of pulmonary arterial hypertension and pulmonary hypertension – Early, simple and reliable DETECTion of PAH in SSc. (ClinicalTrials.gov Identifier: NCT00706082)
Source:
Actelion Pharmaceuticals Ltd.
Role & Effort:
Sub-Investigator
Dates:
2008 - 2012
  
Title:
NIH, “A novel cardiovascular stent for the intrinsic reduction of restenosis and thrombus formation,” Small Business Technology Transfer (STTR) Award - R41
Source:
Vascular Prolifix, LLC
Role & Effort:
Sub-Investigator
Dates:
2008 - 2009
Direct Funds:
$99,983
  
Title:
ARISTOTLE: A Phase 3, Active (Warfarin) Controlled, Randomized, Double Blind, Parallel Arm Study to Evaluate Efficacy and Safety of Apixaban in Preventing Stroke and Systemic Embolism in Subject with Nonvalvular Atrial Fibrillation. (ClinicalTrials.gov Identifier: NCT00412984)
Source:
Bristol-Myers Squibb
Role & Effort:
Sub-investigator
Dates:
2008 - 2011
  
Title:
A multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of SCH 530348 in addition to Standard of Care in Subjects With Acute Coronary Syndrome: Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRA-CER) (ClinicalTrials.gov Identifier: NCT00527943)
Source:
Schering-Plough Research Institute
Role & Effort:
Sub-Investigator
Dates:
2009 - 2012
  
Title:
Clinical and Translational Science Institute of Southeastern Wisconsin, “Computational Cardiology: Translating theoretical and subject-specific computational fluid dynamics results into a specialized stent for coronary artery bifurcation lesions”
Source:
Translational Opportunity Grant of the Pilot and Collaborative Clinical and Translational Research Grants program
Role & Effort:
Principal Investigator
Dates:
2009 - 2010
Direct Funds:
$45,000
  
Title:
A Placebo-Controlled , Double-Blind, Randomized, Multi-Center Study to Assess the Effects of Dronedarone 400 mg BID for 12 weeks on Atrial Fibrillation Burden in Subjects with Permanent Pacemakers. DRONE_L_04316. (HESTIA) (ClinicalTrials.gov Identifier: NCT01135017)
Source:
Sanofi-Aventis U.S. Inc.
Role & Effort:
Sub-Investigator
Dates:
2010 - 2012
  
Title:
A Placebo-Controlled, Double-Blind, Randomized, Multi-center Study to Assess the Effects of Dronedarone 400 mg BID on Cardiac Geometry and Function in Patients With Atrial Fibrillation and Left Atrial Enlargement. (ODYSSEUS) (ClinicalTrials.gov Identifier: NCT01135017)
Source:
Sanofi-Aventis U.S. Inc.
Role & Effort:
Sub-Investigator
Dates:
2010 - 2012
  
Title:
A multicenter, randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy, safety, and tolerability of ixmyelocel-T in subjects with critical limb ischemia and no options for revascularization [PROTOCOL NUMBER: 55-1009-1]. REVIVE-CLI. (ClinicalTrials.gov Identifier: NCT01483898)
Source:
Aastrom Biosciences, Inc.
Role & Effort:
Sub-Investigator
Dates:
2012 - 2013
  
Title:
A randomized, double-blinded, placebo-controlled, phase IIa dose-ranging study to assess the safety, pharmacokinetics, and tolerability of multiple doses of sodium nitrite in diabetic patients with peripheral arterial disease (PAD) – SONIC TheraVasc-TV1001-002. (ClinicalTrials.gov Identifier: NCT01401517)
Source:
Theravasc, Inc.
Role & Effort:
Sub-Investigator
Dates:
2012 - 2013
  
Title:
“Determining the Risks of Magnetic Resonance Imaging in the Presence of Pacemakers and Implantable Cardioverter Defibrillators.” (MagnaSafe Registry) (ClinicalTrials.gov Identifier: NCT00907361)
Source:
Scripps Health
Role & Effort:
Sub-Investigator
Dates:
2012 - 2014
  
Title:
CARTO® 3 System and Real-Time Intracardiac Ultrasound for Ablation of Drug Refractory Recurrent Symptomatic Paroxysmal AF: Acute Procedural Outcomes Study. (IUAF) (ClinicalTrials.gov Identifier: NCT01716663)
Source:
Biosense Webster, Inc.
Role & Effort:
Sub-Investigator
Dates:
2012 - 2013
  
Title:
Amplatzer™ Cardiac Plug (ACP) Clinical Investigational Plan. (ClinicalTrials.gov Identifier: NCT01118299)
Source:
St. Jude Medical.
Role & Effort:
Sub-Investigator
Dates:
2013 - 2014
  
Title:
“A randomized, crossover design study of acute and chronic effects of sitagliptin on endothelial function in humans with type 2 diabetes on background metformin therapy”.(ClinicalTrials.gov Identifier: NCT01859793)
Source:
Merck Sharp &Dohme Corp., Investigator Initiated Trial
Role & Effort:
Sub- investigator
Dates:
2013 - 2016
  
Title:
SynCardia Freedom Driver System Study. (ClinicalTrials.gov Identifier: NCT00733447)
Source:
SynCardia Systems, Inc.
Role & Effort:
Sub-Investigator
Dates:
2013 - 2014
  
Title:
“Toward predictive personalized stenting to reduce restenosis and thrombosis” Proposed - A1
Source:
Marquette University
Role & Effort:
Sub-Investigator
Dates:
11/01/2014 - 2014
Direct Funds:
$105,557
  
Title:
Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Ischemic Heart Failure (RETRO-HF) (ClinicalTrials.gov Identifier: NCT01961726)
Source:
Juventas Therapeutics, Inc.
Role & Effort:
Principal Investigator
Dates:
2014 - 2015
  
Title:
Vascular Reactivity Assessment by a Novel Diagnostic Device, ANGIODEFENDER™, compared to using Brachial Artery Ultrasound Imaging (Protocol A-1302).”
Source:
Everist Health
Role & Effort:
Sub-Investigator
Dates:
2015 - 2016
  
Non-Peer Review
Title:
Physician characteristics, costs, and outcomes related to patients undergoing coronary interventions. A cooperative study between Blue-Cross/Blue-Shield of Georgia and the Medical College of Georgia’s Center for Healthcare Improvement
Source:
Medical College of Georgia’s Center for Healthcare Improvement
Role & Effort:
Principal investigator
Dates:
1998 - 2000
  
Title:
A prospective evaluation of continuous intra-arterial blood gas monitoring in patients undergoing complex coronary interventions
Source:
Internal
Role & Effort:
Principal investigator
Dates:
1998 - 1999
  
Title:
The long-term follow-up of patients with microvascular disease
Source:
Internal
Role & Effort:
Principal Investigator
Dates:
1998 - 2000
  
Title:
The formation of a retrospective database of coronary interventions
Source:
Internal
Role & Effort:
Principal investigator
Dates:
1998 - 2000
  
Title:
Clinical and pharmacologic outcomes for use of Kytril (Granisetron Hydrochloride) in the cardiac catheterization laboratory
Source:
Roche Laboratories
Role & Effort:
Principal investigator
Dates:
1999 - 2000
  
Title:
“Quantifying alterations in coronary artery hemodynamics using medical imaging data and computational fluid dynamics.”(Computational Modeling of Coronary Artery Blood Flow)
Source:
Marquette University internal funding
Role & Effort:
Principal investigator
Dates:
2009 - 2016
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
International
2008 Transcatheter Cardiovascular Therapeutics 2008, Washington, D.C. Viacor PTMA Case Presentation and Discussion.
 
National
1995 International Business Communications Restenosis Summit. Boston, MA, Nitric oxide as therapy for restenosis.
Washington, DC. Drug Eluting Stents: Medicine or Marketing?
RESPECT Investigators Meeting RESPECTful Experience
Current Effort with the Patent Foramen Ovale
2003 UHC Technology Assessment Symposium: Drug-eluting stents, Scottsdale, AZ. Drug-eluting stents and difficult patient subsets: what do we know?
2003 UHC Technology Assessment Update, Web Teleconference. Drug-eluting stent update.
2005 National Association of Health Data Organizations 20th Annual Meeting
2006 AGA Medical, Inc.
 
Regional
1997 Medical College of Georgia 29th Annual Internal Medicine Review, Sea Island, GA. Mitral valve prolapse--separating facts from fiction. Acute myocardial infarction--recognition and which therapy for which patient? Myocardial revascularization--rapidly evolving advances
1998 Stanford University, Cardiology Conference, Stanford, CA. Coronary
1995 American College of Cardiology, Georgia Chapter, Annual Meeting, Atlanta, GA. Beyond Syndrome X: the functional angiogram. Nitric oxide and interventional cardiology.
1996 32nd Annual Primary Care/Family Practice Symposium. Sea Island, GA. Acute myocardial infarction--recognition and therapy.
intervention in African-Americans: What do we really know?
1998 AAPA 27th Annual Conference, Atlanta, GA. Chest Pain.
2003 VHA Central Clinical Conference, Dayton OH. Drug-eluting stents: the
changing frontier.
2003 VHA East Atlantic Interventional Cardiology Council, web conference
Milwaukee, WI. Drug-eluting stents.
2014 Seventh Annual Wisconsin Diabetes Symposium, Milwaukee, WI. Management of the patient with diabetes and coronary artery disease: macrovascular considerations.
 
Local
1994 Hewlett Packard Scientific Advisory Board, Andover, MA, 1994. Nitric oxide: a multifunctional vascular regulator.
2002 Medical College of Wisconsin, Department of Medicine Grand Rounds, Milwaukee, WI. Percutaneous approaches to peripheral vascular disease.
2002 St. Francis Hospital Clinical Conference, Milwaukee, WI. Current therapy for
acute coronary syndrome.
Seminar, Milwaukee, WI. Catheterization laboratory update.
Current therapy for restenosis.
2004 AACN-GMAC Educational Program, Milwaukee, WI. New treatment modalities in the catheterization laboratory.
2005 Medical College of Wisconsin Congestive Heart Failure Symposium
2005 Medical College of Wisconsin Alumni Update, Milwaukee, WI. Disruptive
2006 Medical College of Wisconsin, Department of Medicine Grand Rounds, Milwaukee, WI. Drug-Eluting Stents: Evidence Based or Marketing?
2006 Medical College of Wisconsin Affiliated Hospital General Medical Education
2007 Medical College of Wisconsin Alumni Update, Milwaukee, WI. Coronary
2010 Medical College of Wisconsin, Department of Medicine New Faculty Orientation Program. Roles and goals for individual faculty and the DOM in the clinical enterprise.
2014 Froedtert Hospital, Community Education, Milwaukee, WI. Cardiovascular Clinical Trial Overview.
2014 Medical College of Wisconsin, Tech Terns Program, Milwaukee, WI. The importance of facilities for the future of medicine.
2014 Medical College of Wisconsin, Department of Medicine New Faculty Orientation Program. Roles and goals for individual faculty and the DOM in the clinical enterprise.
2014 Hamilton High School, Milwaukee, WI. Next generation of health care workers.
2015 Medical College of Wisconsin, Cardiovascular Grand Rounds. Milwaukee, WI. Management of the Patient with Coronary Artery Disease and Diabetes: Macrovascular Considerations, "What Is Past Is Prologue"
 
1996 Medical College of Georgia Grand Rounds, Augusta, GA. Nitric oxide and interventional cardiology. Chest pain and normal coronary arteries.
1997 Medical College of Georgia Grand Rounds, Augusta, GA. Indications for angioplasty and stents.
1997 Central State Hospital CME Program, Milledgevile, GA. Acute myocardial
Infarction. Chest pain in normal coronary arteries. Mitral valve prolapsed Update in interventional cardiology.
1998 Medical College of Georgia Cardiology Grand Rounds, Augusta, GA. Does practice make perfect?
2002 Milwaukee County Emergency Medical Services, Annual Educational
Seminar, Milwaukee, WI. Catheterization laboratory update.
2002 Aurora Sinai Medical Center, Cardiology Conference, Milwaukee, WI.
2002 Medical College of Wisconsin, Milwaukee, Department of Surgery Grand
Rounds, Milwaukee, WI. Current therapeutic options for myocardial
infarction.
2003 Medical College of Wisconsin, Milwaukee, WI. MCW Council.
Interventional cardiology in 2004.
2003 Medical College of Wisconsin, Milwaukee, WI. Symposium for Senior
Physicians Interventional cardiology in 2003: Drug eluting stents and more.
2003 VA Medical Center, Milwaukee, VA Grand Rounds, Milwaukee, WI.
Cardiovascular considerations in erectile dysfunction.
2005 Medical College of Wisconsin, Cardiology Grand Rounds. Milwaukee, WI. Drug eluting stents: Insights into complex medical progress.
Milwaukee, WI. Medical economics of congestive heart failure.
technology and cardiovascular medicine.
2006 Medical College of Wisconsin, Cardiac Stroke Symposium, Milwaukee
Retreat Content Expert: Faculty Disclosure and Accountability
2007 Medical College of Wisconsin, Cardiovascular Fellows Core Curriculum. Intra-aortic Balloon Pumps: Use and Abuse. Introduction to Business Principles in Medicine for Fellows.
Artery Disease: Angioplasty, Stents or Bypass Surgery?
2008 Medical College of Wisconsin, Cardiovascular Grand Rounds. Milwaukee, WI. Current Perspectives in Percutaneous Valve Repair: Marrying the Patient with the Technology.
2013 Medical College of Wisconsin, Department of Medicine New Faculty Orientation Program. Roles and goals for individual faculty and the DOM in the clinical enterprise.
 

COMMITTEE SERVICE:
Medical College of Wisconsin
2000 - Present Member/Interviewer, Intern Selection Committee, Medical College of Wisconsin
2000 - Present Member, Fellow Selection Committee, Medical College of Wisconsin
2004 - 2005 Director, Milwaukee EMS Cardiology Practicum, Medical College of Wisconsin
2005 - 2006 Member, Ad Hoc Advisory Committee for Professional and Institutional Practices in Human Research, Medical College of Wisconsin
2005 - 2007 Member, Compensation Committee, Cardiology, Medicine, Medical College of Wisconsin
2006 - 2008 Member, Nominations Committee, Medical College of Wisconsin
2007 - Present Member, Ad Hoc Research Conflict of Interest Committee, Medical College of Wisconsin
2007 - 2008 Member, Practice Planning Committee, Medical College Physicians
2009 - Present Member, MCP/FH Joint Marketing Committee, Medical College of Wisconsin
2012 - Present Chair, Ad Hoc Non-Cancer Center Clinical Trials Exploratory Committee, Medical College of Wisconsin
2013 - 2016 Patient Safety and Quality Officer, Medical College of Wisconsin
2013 - Present Senior Scientific Advisor, Research Strategy Cardiovascular Workgroup, Medical College of Wisconsin
2015 - 2017 Co-Chair, Search Committee for Chief of Cardiothoracic Surgery, Medical College of Wisconsin
2015 - 2016 Co-Chair, Search Committee for Medical Director, Advanced Heart Failure, Medical College of Wisconsin
2016 - 2017 Search Committee for Chief of Cardiovascular Medicine, Medical College of Wisconsin
 
Hospital
2000 - 2018 Director, Cardiac Catheterization Laboratory Morbidity and Mortality Review, Froedtert Hospital
2003 - 2005 Member, Cardiovascular Steering Committee, (Joint), Froedtert Hospital
2003 - 2005 Member, Supply Cost Initiative Steering Committee, Froedtert Hospital
2006 - 2008 Member, Vascular Care Strategic Planning Committee (Joint), Froedtert Hospital
2006 - 2008 Member, Cardiac Care Strategic Planning Committee, (Joint), Froedtert Hospital
2009 - Present Member, Inpatient Services Operations Committee, Froedtert Hospital
2009 - 2013 Member, Readmission Steering Group (Joint), Froedtert Hospital
2009 - Present Member (Co-Chair 2013-present), SEAc PPI Sub-Committee, Froedtert Hospital
2009 - Present Member, Hospital Advisory Committee, Froedtert Hospital
2009 - Present Member, Inpatient Services Steering Committee, Froedtert Hospital
2009 - 2013 Member, Outpatient Business Process Team (Juran) (Joint), Froedtert Hospital
2010 - Present Member, Joint Quality Committee (Joint), Froedtert Hospital
2012 - Present Member, Capital Budget Committee, Froedtert Hospital
2013 - 2014 Member, Joint Organizational Excellence Committee (Joint), Froedtert Hospital
2014 - Present Member, Value Based Care Initiative Executive Committee, Froedtert Hospital
 

MCW TEACHING ACTIVITIES:
Medical Student Education
2008 - 2017 Lecturer, Introduction to Internship Course
 
Resident and Fellow Education
2000 - Present Cardiology ward and consult attending
2000 - Present Invasive/interventional cardiology instruction including coordination, curriculum, and education in the technical and intellectual arts of invasive and interventional cardiology.
2000 - Present Cardiology Ward and Consultation Attending
2000 - Present Lecturer, cardiology fellow core conference, cardiology grand round presentations, direct cardiology catheterization conference, clinical research advocate/advisor.
Emergency Medicine Grand Rounds Presentations
 

EXTRAMURAL TEACHING:
Medical Student Education
2002 - 2003 Second year physical diagnosis cardiology course director; Clinical Advisor for Clinical Education During Research (CEDR); Medical Scientist Training Program (MSTP); and ICE Clinical Teacher
2004 - 2006 Health Profession Undergraduate Students, Director, Milwaukee EMS Cardiovascular Practicum
2010 Health Profession Undergraduate Students, Shadowing experience for Summer Program for Undergraduate Research (SPUR).
2011 - Present Master Clinician Pathway Faculty Advisor
 
Continuing Medical Education
2005 - Present Tip-TV™ Training in Partnership Program Supplement for Imaging Professionals, XR: Cardiac Interventions. GE Healthcare, Waukesha, WI
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Marks DS, Vita JA, Keaney JF Jr., Loscalzo J., Journal of Clinical Investigation 1995; 96:2630-2638, Complete Inhibition of Neointimal Hyperplasia Following Vascular Injury by a Unique Adduct of Nitric Oxide.
2. Burchenal JEB, Marks DS, Schweiger MJ, Mann JT, Rothman MT, Ganz P, Adelman B, Bittl JA, American Journal of Cardiology 1998;82:511-515, Effects of Direct Thrombin Inhibition with Bivalirudin (Hirulog) on Restenosis After Coronary Angioplasty.
3. Seligman RW, Robinson JBV, Marks DS, Catheterization and Cardiovascular Interventions 1999;46;218-222, Functional Assessment of Internal Mammary Artery Bypass Grafts.
4. Alla SR, Jagadesan M, Marks DS, The Journal of Invasive Cardiology 1999; 11:627-630, Dilutional Acidosis Complicating Rotational Atherectomy.
5. Marks DS, Mensah GA, Kennard ED, Detre K, Holmes DR. The American Heart Journal 2000:140(1):162-9, Race, Baseline Characteristics, and Clinical Outcomes After Coronary Intervention: The New Approaches in Coronary Interventions (NACI) Registry.
6. Robinson VJB, Corley JH, Marks DS, Eberhardt LW, Eubig C, Burke GJ, Prisant LM. American Journal Roegenology 2000;174(5):1349-52, Causes of Transient Dilation of the Left Ventricle During Myocardial Perfusion Imaging.
7. East MA, Jollis JG, Nelson CL, Marks D, Peterson ED. Journal of the American College of Cardiology 2003;41(6):949-54, The Influence of Left Ventricular Hypertrophy on Survival in Patients With Coronary Artery Disease: Do Race and Gender Matter?
8. Naidu SS, Selzer F, Jacobs A, Faxon D, Marks DS, Johnston J, Detre K, Wilensky RL. American Journal of Cardiology 2003;92(10):1160-4, Renal Insufficiency is an Independent Predictor of Mortality After Percutaneous Coronary Intervention.
9. Marks DS, Gudapati S, Prisant LS, Weir B, diDonato-Gonzalez C, Waller JL, Houghton JL. Journal of Clinical Hypertension 2004;6(6):304-309. Mortality in Patients with Microvascular Disease.
10. Mehta RH, Marks DS, Califf RM, Sohn S, Pieper KS, Van de Werf F, Peterson ED, Ohman EM, White HD, Topol EJ, MD, Granger CB. American Journal of Medicine 2006;119:70.e1-70e8. Differences in the Clinical and Angiographic Features and Outcomes in African American and Caucasians with Acute Myocardial Infarction.
11. Mannebach PC, Dieter RS, Marks DS. Angiology 2006;57:526-529. Use of Gadolinium-Based Angiography for Renal Artery Stenting in a Patient with Renal Insufficiency.
12. Sack S, Kahlert P, Bilodeau L, Pièrard LA, Lancellotti P, Legrand V, Bartunek J, Vanderheyden M, Hoffmann R, Schauerte P, Shiota T, Marks DS, Erbel R, Ellis SG. Circulation: Cardiovascular Interventions 2009, 2:277-284. Percutaneous Transvenous Mitral Annuloplasty: Initial Human Experience with a Novel Coronary Sinus Implant Device.
13. Timothy J. Gundert TJ, Marsden AJ, Yang W, Marks DS, LaDisa JF Jr. IEEE Transactions on Biomedical Engineering 2012, 59:1992-2002. Identification of Hemodynamically Optimal Coronary Stent Designs Based on Vessel Diameter.
14. Singh S, Tarima S, Rana V, Marks DS, Conti M, Idstein K, Biblo LA, Fletcher KE. Journal of Hospital Medicine (Online) 2012, 7(7);551-6. Impact of Localizing General Medicine Teams to a Single Nursing Unit.
15. Caroll JD, Saver JL, Thaler DE, Smalling RW, Berry S, MaDonald LA, Marks DS, Tirschwell DL. New England Journal of Medicine 2013, 368:1092-100. Closure of Patent Foramen Ovale versus Medical Therapy after Cryptogenic Stroke
16. Karn D, Marks DS, Wein M, Kong AL. J Womens Health 2015, 24(10); 795-800. Benign Arterial Calcification on Screening Mammogram: A Marker for Coronary Artery Disease?
17. Ellwein L, Marks DS, Migrino R, Foley W, Sherman S, LaDisa J. Catheterization and Cardiovascular Interventions 2016, 87(7):1244-1255. Image-Based Quantification of 3D Morphology for Bifurcations in the Left Coronary Artery: Application to Stent Design.
18. Saver J, Carroll J, Thaler D, Smalling R, MacDonald L, Marks DS, Tirschwell D. New England Journal of Medicine; 2017, 377:1022-1032. Long-Term Comparison of Closure of Patent Foramen Ovale versus Medical-Therapy after Cryptogenic Stroke.
19. Tirschwell DL, Turner M, Thaler D, Choulerton J, Marks D, Carroll J, MacDonald L, Smalling RW, Koullick M. Gu NY, Dhoble A, Saver J. Journal of Medical Economics. Cost-effectiveness analysis of percutaneous device closure as secondary stroke prevention in patients with a patent foramen ovale who survived a prior cryptogenic stroke. https://doi.org/10.1080/13696998.2018.1456445 (Accepted).
 
Books, Chapters, and Reviews
1. Marks DS and Loscalzo J.: Vasoreactive Diseases; Molecular Approach in Molecular Interventions and Local Drug Delivery in Cardiovascular Disease. Edelman ER, ed. WB Saunders, LTD., London, 1995.
2. Cummings JP, Carroll JD, Marks DS, Matuszewski KA, Ratko TA, Skiles D. Technology Report: Drug-Eluting Stents. UHC Clinical Practice Advancement Center Monograph. University Health System Consortium, Oak Brook, IL, 2002.
3. Ratko TA, Cummings JP, Marks DS, Matuszewski KA. UHC High-Impact Technology Brief: Transcatheter Closure of Atrial Septal Defects. University Health System Consortium, Oak Brook, IL, 2005.
 
Abstracts
1. Simpson JB, Johnson DE, Thaplliyal HV, Marks DS, Braden LJ :Transluminal Atherectomy: A New Approach to Atherosclerotic Vascular Disease. Circulation ; 72:111-146, 1985.
2. Marks DS, Osborne JA, Daley WL, Keaney JF, Scharfstein J, Himmel K, Oscalzo J, Vita JA. Regression Diet Produces a Hypercontractile State in the Coronary Arteries of Miniature Swine. Clinical Research; 40(2):274A, 1992.
3. Daley WL, Keaney JF, Scharfstein J, Marks DS, Himmel K, Loscalzo J, Vita JA, Improvement in Endothelial Vasomotor Function Precedes Physical Regression of Atherosclerosis in Swine Iliac Arteries. Clinical Research; 40(2):150A 1992.
4. Marks DS, Osborne JA, Himmel KS, Vita JA, Vasomotor Consideration in the Choice of Contrast Media, Journal of the American College of Cardiology, 21(2Suppl A);208A, 1993.
5. Marks DS, Vita JA, Keaney JF Jr., Loscalzo J, Complete Inhibition of Neointimal Hyperplasis Following Vascular Injury by a Unique Adduct of Nitric Oxide. Circulation; 90 (4Pt2): 1-298, 1994.
6. Meckel CR, Ahmed W, Ferguson JJ, Strony J, Marks DS, Manuelian D, Adelman B, Bittl J, on behalf of the Hirulog Angioplasty Study Investigators. Angiographic Predictors of Severe Dissection During Balloon Angiopalsty A report from the Hirulog Angioplasty Study. Circulation; 90(4Pt2):I-64, 1994.
7. Marks DS, Vita JA, Keaney JR, Jr., Loscalzo J, Inhibition of Coronary Vasospasm Following Balloon Injury by a Unique Adduct of Nitric Oxide. Circulation; 92(8):1-392, 1995.
8. Burchenal JEB, Marks DS, Schweiger MJ, Mann JT, Rothman MT, Adelman B, Bittle JA., Direct Thrombin Inhibition with Hirulog Does Not Prevent Restenosis After Coronary Angioplasty. Circulation; 92(8): 1-608, 1995.
9. Davis SF, Marks DS, Wang F, Ganz P, Mudge GH. Cytomegaloviris Accelerates Allograft Arteriosclerosis in Cardiac Transplant Recipients. Journal of the American College of Cardiology; 27(2 Suppl A):283A, 1996.
10. Marks DS, Pompili VH, Jeong MH, Owen WG, Katusic ZS, Holmes DR, Swartz RS. Sustained Tissue Nitric Oxide Release After Local Delivery of a Novel Nitric Oxide Donor. Journal of the American College of Cardiology; 27(2suppA):217A, 1996.
11. Schwartz RS, Marks DS, Srivatsa SS, Camrud AR, Camrud LJ, Katusic ZS. Local Nitric Oxide Synthase Inhibition Caused Marked Coronary Neointimal Hyperplasia and Platelet Thrombosis; Circulation; 94(8);1-154, 1996.
12. Robinson VJB, Gunter LE, Marks DS, Raibon SA, Ohdav AC, Corley JH, Eubig J, Yoder H, Burke GJ, Localized Transient Ischemic Dilation as a Marker of Severe Coronary Artery Stenosis. Journal of Investigative Medicine; 46:30a, 1998.
13. Marks DS, Mensah GA, Kennard ED, Holmes DR. Importance of Gender in Predicting Long-term Clinical Outcomes in African-Americans Undergoing Coronary Interventions. Journal of the American College of Cardiology; 33:2A, 1999.
14. Marks DS, Mensah GA, Kennard ED, Holmes DR. Significant Differences in Baseline Characteristics of African-American Patients Undergoing Coronary Interventions. Journal of the American College of Cardiology; 33:2A, 1999.
15. Seligman RW, Robinson JBV, Venkatesh B, Shah VB, Eubig C, Litaker M, Corley J, Marks DS, Raibon S, Reece S, Dicks G, Yoder J, Burke G. Adenosine Infusion in Humans Dilates Conduit Veins. FASEB Journal; 13:a108, 1999.
16. Seligman RW, Robinson JBV, Venkatesh B, Shah VB, Eubig C, Litaker M, Corley J, Marks DS, Raibon S, Reece S, Discs G, Yoder J, Burke G. Adenosine Infusion in Humans Dilates Conduit Veins. Journal of Investigative Medicine; 47;208a, 1999.
17. Theodorakis MH, Marks DS, Rubin JW, Catarrhs JD. Effects of Adenosine on Coronary Endothelium-Bound (CCEB) Angiotensin-Converting Enzyme (ACE) - substrate Hydrolysis, In Vivo. 1999 Vaso.
18. Marks DS, Effron MB, Mensah GA, Fitzpatric S, Tcheng JE, Kereiakes DJ. Abciximab Markedly Reduces 30-day Adverese Outcomes in Blsck Patients Undergoing Coronary Interventions. Circulation; 100:I-104, 1999.
19. East MA, Buell HE, Jollis JG, Marks DS, Peterson ED. Left Ventricular Hypertrophy Partly Accounts for Survival Differences between Black and White Patients. Circulation;102:I-266, 2000.
20. Marks DS, Mensah GA, Bastos EM, Califf RM. Increased Late Mortality in Black Patients Treated with Thrombolysis. Circulation;102:II-795, 2000.
21. Marks DS, Gudapati SB, Waller J, Houghton JL, Prisant LM, Carr AA, Weir EB, diDonato-Gonzalez C. Coronary Flow Reserve Predicts Mortality in Patients with Suspected Myocardial Ischemia and Normal Coronary Arteries. Journal of the American College of Cardiology; 35:384A, 2000.
22. Taylor AT, Athar MM, Marks DS, Wagner PJ, diDonato-Gonzalez C. Depression and Anxiety Modifies the Expression of Coronary Artery Disease. 13th Asean Congress of Cardiology - Singapore, June 2000.
23. Marks DS, Gudapati SB, Kleczka JF, Murphy SA, Cannon CP, Braunwald E, Gibson CM. Electrocardiographic Left Ventricular Hypertrophy is Associated with Mortality and Left Ventricular Rupture in Patients with Acute Myocardial Infarction. Journal of the American College of Cardiology 39:331A, 2002.
24. Naidu SS, Selzer F, Jacobs AK, Faxon D, Marks DS, Johnston JM, Detre K, Wilensky RL. Renal Insufficiency is an Independent Predictor of Mortality After Percutaneous Coronary Intervention: Current Results From the NHLBI Dynamic Registry. Journal of the American College of Cardiology 41:1A, 2003.
25. Marks DS, Ratko TA, Matuszewski KA, Oinonen MJ, Cummings JP. Utility of an Online Clinical Database for Tracking Innovative Technology: The Academic Drug Eluting Stent Experience. Journal of the American College of Cardiology 43:399A, 2004.
26. Marks DS, Ratko TA, Matuszewski KA, Oinonen MJ, Cummings JP. Clinical and Demographic Impact of Drug Eluting Stents: The US Academic Experience. Journal of the American College of Cardiology 43:402A, 2004.
27. Mehta RH, Marks DS, Sohn S, Granger CB. African Americans Have Higher Long-term Mortality and More Stroke and Bleeding Than Caucasians Followin g Reperfusion Therapy for Acute Myocardial Infarction. Circulation 111:III-798, 2004.
28. Grant ME, Oinonen MJ, Cummings JP, Matuszewski KA, Marks DS. Impact of Glycoprotein Use on Clinical and Economic Outcomes in PCI Stented Patients in Academic Health Centers. Annual Meeting of the American College of Clinical Pharmacology, Dallas, TX, 2004.
29. Marks DS, Cummings JP, Oinonen MJ, Yun HJ, Ratko TA, Matuszewski KA. Financial and Clinical Factors Associated With the Use of Drug Eluting Stents: A Temporal Analysis. Journal of the Americal College of Cardiology. 45:17A, 2005.
30. Marks DS, Cummings JP, Oinonen MJ, Yun HJ, Ratko TA, Matuszewski KA. Financial, Clinical and Social Factors Associated With the Utilization of Drug Eluting Stents. Journal of the Americal College of Cardiology. 45:73A, 2005.
31. Zouras KW, Kleczka J, Marks DS, Siegel R, Presberg K, Woods T, Cinquegrani M, Syed A, Syed A, Soto FJ. Nitroprusside (NTP) in the Assessment of Pulmonary Hypertension (PH) Associated with Elevated Left Ventricular (LV) Filling Pressures due to Diastolic Dysfunction. Chest: 128:138S-a, 2005.
32. Soto FJ, Siegel R, Marks DS, Kleczka J, Woods T, Maloney JP, Syed A, Syed A, Gupta S, Presberg K. Performance of Pulmonary Capillary Wedge Pressure (PCWP) vs. Left Ventricular End Diastolic Pressure (LVEDP) in the Diagnosis/Classification of Patients with Suspect Pulmonary Arterial Hypertension (PAH). Chest 128:137S-a.
33. Zouras W, Siegel R, Cinquegrani M, Marks DS, Kleczka J, Presberg K, Woods T, Soto FJ. Changes in V Wave During a Nitric Oxide Vasodilator Trial: Unmasking Left Ventricular Dysfunction. AJRCCM 3:A168, 2006.
34. Gupta N, Kleczka J, Siegel R, Presberg K, Marks DS, Zouras W, Soto FJ. Estimation of Cardiac Index In Patients With Pulmonary Hypertension: Thermal Dilution Vs. Fick's Method. AJRCCM 3;A416, 2006.
35. Soto FJ, Jain P, Kleczka J, Siegel R, Woods T, Marks DS Presberg K. Clinical and Hemodynamic Impact of Subcutaneous (SQ) Treprostinil in the Management of Pulmonary Arterial Hypertension (PAH): Single Center Experience. Chest 2006; 130S (4): 120S.
36. Soto FJ, Girotra S, Cain H, Kleczka J, Siegel R, Marks DS, Woods T, Janusz J, Presberg KW. Longer Time Interval Between Infusion Site Changes for Subcutaneous (SQ) Treprostinil (Remodulin ®) in Patients with Pulmonary Hypertension (PH): Tolerance and Safety. Am J Resp Crit Care Med A401, Volume 175, April 2007.
37. Jacob S, Goyal A, Presberg K, Csuka ME, Kleczka J, Siegel R, Marks DS, Soto FJ. Prevalence of Elevated Left Ventricular End-Diastolic Pressure (LVEDP) in Patients With Connective Tissue Disease (CTD) and Pulmonary Hypertension (PH) Accepted for Poster presentation, ATS Meeting, Toronto, Canada May 2008.
38. Sack S, Kahlert P, Hoffman R, Pierard L, Lancellotti P, Legrand V, Bartunek J, Vanderheyden M, Bilodeau L, Shiota T, Marks DS, Ellis S. Percutaneous Transvenous Mitral Annuloplasty: Clinical Development of a Novel Coronary Sinus Device. Journal of the American College of Cardiology 51 (10 Supp A), A75, 2008.
39. Williams A, Freeman J, Migrino R, Koo B, Marks DS, Foley D, LaDisa J, Jr. Computational simulations from CT angiography demonstrate altered hemodynamics in realistic stented coronary artery bifurcations. Annals of Biomedical Engineering, Biomedical Engineering Society, Pittsburgh, 2009.
40. Nomeland S, Migrino R, Marks DS, LaDisa J, Jr. Image-based quantification of 3-D morphology for bifurcations in the left coronary artery: application to stent design. Accepted for podium presentation - FDA Computational Modeling for Cardiovascular Devices workshop in Rockville, MD, 2010.
41. Simpson JB, Johnson DE, Thaplliyal HV, Marks DS, Braden LJ :Transluminal Atherectomy: A New Approach to Atherosclerotic Vascular Disease. Circulation ; 72:111-146, 1985.
42. Marks DS, Osborne JA, Daley WL, Keaney JF, Scharfstein J, Himmel K, Oscalzo J,
43. Vita JA. Regression Diet Produces a Hypercontractile State in the Coronary Arteries of Miniature Swine. Clinical Research; 40(2):274A, 1992.
44. Daley WL, Keaney JF, Scharfstein J, Marks DS, Himmel K, Loscalzo J, Vita JA, Improvement in Endothelial Vasomotor Function Precedes Physical Regression of Atherosclerosis in Swine Iliac Arteries. Clinical Research; 40(2):150A 1992.
45. Marks DS, Osborne JA, Himmel KS, Vita JA, Vasomotor Consideration in the Choice of Contrast Media, Journal of the American College of Cardiology, 21(2Suppl A);208A, 1993.
46. Marks DS, Vita JA, Keaney JF Jr., Loscalzo J, Complete Inhibition of Neointimal Hyperplasis Following Vascular Injury by a Unique Adduct of Nitric Oxide. Circulation; 90 (4Pt2): 1-298, 1994.
47. Meckel CR, Ahmed W, Ferguson JJ, Strony J, Marks DS, Manuelian D, Adelman B, Bittl J, on behalf of the Hirulog Angioplasty Study Investigators. Angiographic Predictors of Severe Dissection During Balloon Angiopalsty A report from the Hirulog Angioplasty Study. Circulation; 90(4Pt2):I-64, 1994.
48. Marks DS, Vita JA, Keaney JR, Jr., Loscalzo J, Inhibition of Coronary Vasospasm Following Balloon Injury by a Unique Adduct of Nitric Oxide. Circulation; 92(8):1-392, 1995.
49. Burchenal JEB, Marks DS, Schweiger MJ, Mann JT, Rothman MT, Adelman B, Bittle JA., Direct Thrombin Inhibition with Hirulog Does Not Prevent Restenosis After Coronary Angioplasty. Circulation; 92(8): 1-608, 1995.
50. Davis SF, Marks DS, Wang F, Ganz P, Mudge GH. Cytomegaloviris Accelerates Allograft Arteriosclerosis in Cardiac Transplant Recipients. Journal of the American College of Cardiology; 27(2 Suppl A):283A, 1996.
51. Marks DS, Pompili VH, Jeong MH, Owen WG, Katusic ZS, Holmes DR, Swartz RS. Sustained Tissue Nitric Oxide Release After Local Delivery of a Novel Nitric Oxide Donor. Journal of the American College of Cardiology; 27(2suppA):217A, 1996.
52. Schwartz RS, Marks DS, Srivatsa SS, Camrud AR, Camrud LJ, Katusic ZS. Local Nitric Oxide Synthase Inhibition Caused Marked Coronary Neointimal Hyperplasia and Platelet Thrombosis; Circulation; 94(8);1-154, 1996.
53. Robinson VJB, Gunter LE, Marks DS, Raibon SA, Ohdav AC, Corley JH, Eubig J, Yoder H, Burke GJ, Localized Transient Ischemic Dilation as a Marker of Severe Coronary Artery Stenosis. Journal of Investigative Medicine; 46:30a, 1998.
54. Marks DS, Mensah GA, Kennard ED, Holmes DR. Importance of Gender in Predicting Long-term Clinical Outcomes in African-Americans Undergoing Coronary Interventions. Journal of the American College of Cardiology; 33:2A, 1999.
55. Marks DS, Mensah GA, Kennard ED, Holmes DR. Significant Differences in Baseline Characteristics of African-American Patients Undergoing Coronary Interventions. Journal of the American College of Cardiology; 33:2A, 1999.
56. Seligman RW, Robinson JBV, Venkatesh B, Shah VB, Eubig C, Litaker M, Corley J, Marks DS, Raibon S, Reece S, Dicks G, Yoder J, Burke G. Adenosine Infusion in Humans Dilates Conduit Veins. FASEB Journal; 13:a108, 1999.
57. Seligman RW, Robinson JBV, Venkatesh B, Shah VB, Eubig C, Litaker M, Corley J, Marks DS, Raibon S, Reece S, Discs G, Yoder J, Burke G. Adenosine Infusion in Humans Dilates Conduit Veins. Journal of Investigative Medicine; 47;208a, 1999.
58. Marks DS, Effron MB, Mensah GA, Fitzpatric S, Tcheng JE, Kereiakes DJ. Abciximab Markedly Reduces 30-day Adverese Outcomes in Black Patients Undergoing Coronary Interventions. Circulation; 100:I-104, 1999.
59. Carroll JD, Saver JL, Thaler DE, Smalling RW, Berry S, MacDonald LA, Marks DS, Tirschwell DL for the RESPECT Investigators. The RESPECT Trial: The Final Results with Primary End Point Analyses. Presented at TCT 2012.
60. Saver JL, Thaler D, Smalling R, Carroll J, Berry S, MacDonald L, Marks D, Tirschwell D, Book D, Goldstein LB. Qualifying and Outcome Strokes in the RESPECT PFO Trial: Additional Evidence of Treatment Effect. Presented at International Stroke Conference, February 2013.
61. Thaler D, Saver J, Smalling R, Carroll J, Berry S, MacDonald L, Marks D, Tirschwell D, Book D, Goldstein L for the RESPECT Trialists. Further Analysis of Confirmed Endpoint Recurrent Strokes in PFO patients in the RESPECT Trial. Presented at Euro PCR, May 2013.
62. Thaler D, Saver J, Smalling R, Carroll J, Berry S, MacDonald L, Marks D, Tirschwell D, Book D, Goldstein L for the RESPECT Trialists. Effect of Having an Amplatzer Patent Foramen Occlusion Device in Place in the RESPECT Trial. Presented at European Stroke Conference May 2013. Cerebrovascular Dis 2013, 35(Supp 3) 106.
63. Carroll JD, Saver JL, Thaler DE, Smalling R, MacDonald LA, Marks DS, Tirschwell DL for the RESPECT Investigators. Randomized Evaluation of Recurrent Stroke Comparing PFO closure to Established Current Standard of Care Treatment (RESPECT) Trial - Long-Term Results. Accepted as late breaking abstract TCT 2015.
64. Mechanisms of Recurrent Ischemic Stroke Under Medical Versus Device Therapy: Long Term Follow-Up in the RESPECT PFO Trial abstract
65. Smalling RW, Carroll J, Saver J, Thaler D, Bull T, Bauer K, McDonald L, Marks DS, Tirschwell D. Procedural and Long Term Safety of PFO Closure in Cryptogenic Stroke: Insights from the RESPECT Trial. International Stroke Conference. Stroke, 47:AWP422, 2013
66. Tischwell DL, Marks DS, MacDonald L, Smalling RW, Carroll J, Gu NY, Koullick M, Saver J, and Thaler D. Cost-effectiveness of Percutaneous PFO Closure in Patients with Hhistory of Cryptogenic Stroke in the United States. International Society for Pharmacoeconomics and Outcomes 22nd Annual International Meeting. Value in Health, 20:A8, 2017.