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CURRICULUM VITAE

Dawn Felicity Wolfgram MD
Associate Professor
Department of Medicine
Division of Nephrology

OFFICE ADDRESS:
Hub for Collaborative Medicine
8701 Watertown Plank Road
Milwaukee, WI 53226

EDUCATION:
09/1999 - 12/2002 B.S., Majors: Molecular and Cellular Biology and Psychology, University of Wisconsin-Madison, Madison
09/2003 - 05/2007 M.D., University of Wisconsin School of Medicine and Public Health, Madison, WI

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
07/01/2007 - 06/30/2010 Internal Medicine Residency, Medicine, University of Michigan, Ann Arbor, WI
07/2010 - 06/2012 Nephrology Fellowship, Department of Medicine, Division of Nephrology, University of Wisconsin Hospitals and Clinics, Madison, WI

FACULTY APPOINTMENTS:
07/2012 - 07/2018 Assistant Professor of Medicine, The Medical College of Wisconsin, WI, Department of Medicine, Division of Nephrology, Milwaukee, Milwaukee, WI
07/2012 - Present Staff Nephrologist, Section of Medicine, Division of Nephrology, Milwaukee VA Medical Center, Milwaukee, WI
07/2018 - Present Associate Professor of Medicine, Medicine, Nephrology, Medical College of Wisconsin, Milwaukee, WI
12/2018 - Present VA Nephrology Section Chief, Medicine, Nephrology, Zablocki VAMC, Milwaukee, WI

EDUCATIONAL ADMINISTRATIVE APPOINTMENTS:
07/2013 - 10/31/2016 Nephrology Fellowship Associate Program Director, Department of Medicine, Division of Nephrology, Medical College of Wisconsin, Milwaukee, WI
11/01/2016 - 07/01/2018 Nephrology Fellowship Program Director, Medicine, Nephrology, Medical College of Wisconsin

HOSPITAL STAFF PRIVILEGES:
07/2012 - Present Froedtert Memorial Lutheran Hospital, Milwaukee, WI
07/2012 - Present Clement J. Zablocki VA Medical Center, Milwaukee, WI

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
American Board of Internal Medicine
08/2010
12/2020
ABIM - Nephrology
10/2012
12/2022
 
Licensure
Number Issue DateExpiration
Wisconsin License
54313-20
04/16/2010
10/31/2021
 

AWARDS AND HONORS:
06/2000 - Present Medical Scholars Freshman Summer Research Program.
05/2001 - Present Letters and Science Summer Sophomore Apprenticeship Research Grant.
06/2001 - Present Hilldale Undergraduate Research Fellowship Award
06/2004 - Present Shapiro Summer Medical Research Fellowship Award
05/2007 - Present John Curtis Kimberly Award for 4th year Medical Student in Internal Medicine
09/2013 - 06/2015 Clinical Scholars Research Program, Clinical and Translational Science Institute of Southeast Wisconsin
07/2016 - 06/2017 James L Sebastian, MD Outstanding Teaching Award, Medical College of Wisconsin

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
07/2010 - 07/2013 National Kidney Foundation
07/2010 - Present American Society of Nephrology
06/2014 - 12/2016 Central Society for Clinical and Translational Research
01/2015 - 01/2018 International Society for Peritoneal Dialysis

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
01/2014 - Present BMC Nephrology
03/2014 - Present Peritoneal Dialysis International
09/2014 - Present Hemodialysis International
03/2016 - Present Clinical Journal of the American Society of Nephrology
09/2016 - Present Nephrology Self-Assessment and Kidney Self-Assessment Program Panel Reviewer
07/2018 - Present Journal of the American Society of Nephrology

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
06/04/2020 - 06/05/2020 Reviewer, Kidney, nutrition, obesity and diabetes study section, NIH

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
Intradialytic cerebral oximetry and cognitive decline in adults on hemodialysis
Source:
NIH/NIDDK
Role:
PI
Dates:
03/15/2018 - 03/14/2023
Direct Funds:
$882,618
 
Title:
A randomized clinical trial of a communication tool to improve access to palliative care for patients with end-stage renal disease
Source:
NIH
Role:
Site PI
PI:
Schwarze
Dates:
07/01/2019 - 05/31/2021
Direct Funds:
$25,000
 
Title:
Best Case/Worst Case: a multisite randomized clinical trial of scenario planning for patients with end-stage kidney disease
Source:
NIH/NIA
Role:
Site PI
PI:
Gretchen Schwarze
Dates:
06/01/2020 - 02/28/2025
Direct Funds:
$15,000
 
Non-Peer Review
Title:
Changes in Cerebral Perfusion During Hemodialysis
Source:
Kendall Research Grant and Fraternal Order of the Eagles Research Grant
Role:
PI
Dates:
02/2016 - Present
Direct Funds:
$35,000
 
Title:
Cerebrovascular Reactivity Impact on Brain Structure in Hemodialysis Patients
Source:
Daniel M. Soref Charitable Trust
Role:
PI
Dates:
11/10/2020 - Present
Direct Funds:
$5,000
 
Prior
Peer Review
Title:
Thrombospondin and angiogenesis
Source:
Hilldale Research Foundation
Role:
Student Research
PI:
Deane Mosher
Dates:
06/1991 - 08/2001
Direct Funds:
$3,000
 
Title:
Identification of human embryonic stem cells in infarcted mouse myocardium
Source:
Shapiro Summer Reseach Program
Role:
Medical Student Research
PI:
Timothy Kamp
Dates:
06/2004 - 08/2004
Direct Funds:
$3,000
 
Title:
Association between intra-dialytic hypotension and cognitive test scores in patients on dialysis
Source:
Research Affairs Committee and Froedtert Hospital Foundation
Role:
PI
Dates:
05/2013 - 09/2014
Direct Funds:
$25,000
 
Title:
Systolic Blood Pressure Intervention Trial
Source:
NIH/NHLBI/NIA/NIDDK/NINDS
Role:
site co-investigator
PI:
William Cushman
Dates:
09/2013 - 08/2016
 
Title:
Small Equipment Grant
Source:
MCW Research Affairs
Role:
PI
Dates:
05/2018 - Present
Direct Funds:
$15,000
 
Non-Peer Review
Title:
Development of a 16 amino acid probe for use in electron and fluorescent microscopy
Source:
NIC/NCI
Role:
Intramural Research Training Awardee
PI:
Siriam Subramaniam
Dates:
12/2003 - 08/2003
 
Title:
Indicators of renal recovery in patients with acute kidney injury requiring renal replacement therapy
Role:
Resident research
PI:
Micheal Hueng
Dates:
08/2008 - 06/2010
 
Title:
Diuretic dosing in hypercalciuric patients with history of nephrolithiasis and effects on 24 hour urinary calcium excretion
Role:
PI
Dates:
05/2011 - 06/2012
 
Title:
Development of clostridium difficle colitis in peritoneal dialysis patients with peritonitis
Role:
PI
Dates:
12/2011 - 03/2012
 
Title:
Changes in dementia prevalence after dialysis initiation by dialysis modality
Source:
Division of Nephrology Funds
Role:
PI
Dates:
09/2013 - 08/2014
 
Title:
Dialytic hemodynamics and association with gait speed in elderly hemodialysis patients
Source:
Froedtert Hospital Foundation
Role:
PI
Dates:
07/2014 - 03/2015
Direct Funds:
$1,000
 

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Wolfgram Dawn, Geriatric Nephrology, Lunch and Learn at Moorland Reserve Clinic, New Berlin, WI, 05/30/2013
Wolfgram Dawn, Management of hypertension and diabetes in patients with advanced chronic kidney disease, Medical College of Wisconsin- Medicine Grand Rounds, Milwaukee, WI, 04/18/2014
Wolfgram Dawn, Geriatric Nephrology:cognitive and functional outcomes in the dialysis population, Nephrology Division Research Conference, Milwaukee, WI, 01/16/2015
Wolfgram Dawn, Results of the Systolic Blood Pressure Intervention Trial: Implications for blood pressure treatment, Nephrology Research Conference, Milwaukee, WI, 02/02/2016
Wolfgram Dawn, Outcomes in Cognitive and Functional Status in Dialysis Patients, Geriatric Division Research Conference, Milwaukee, WI, 03/04/2016
Wolfgram Dawn, Kidney outcomes in SPRINT, Nephrology Research Conference, Milwaukee, WI, 03/21/2017
Wolfgram Dawn, Management of Hyponatremia, Endocrinology Grand Rounds, Milwaukee, WI, 08/17/2017
Dawn Wolfgram, Intradialytic cerebral oximetry and cognitive outcomes, MCW Division of Geriatrics/Gerontology Research Seminar, Medical College of Wisconsin. Milwaukee, WI, 01/11/2019
 
Regional
Wolfgram Dawn, Geriatric Nephrology, Wisconsin Update in Geriatric Medicine and Board Review Course, Lake Geneva, WI, 09/20/2015
Wolfgram Dawn, Kidney Diseases/Disorders, Wisconsin Update in Geriatric Medicine and Board Review Course, Fontana, WI, 09/29/2017
Dawn Wolfgram and Judith Siers-Poisson, Advancing Kidney Health Initiative on Wisconsin Public Radio, Wisconsin Public Radio-Central Time, Madison, WI, 08/01/2019
Dawn Wolfgram, Cognitive Function In Dialysis, National Kidney Foundation of Wisconsin Dialysis Symposium, Milwaukee, WI (Virtual), 11/12/2020 - Present
 
National
Dawn Wolfgram, Peer Mentoring for Peritoneal Dialysis Program, VA Innovators to Experience Demo Day, Washington, DC, 08/29/2018
 
International
Dawn Wolfgram, Brain-Kidney Axis, American Society of Nephrology, Washington, DC, 11/07/2019
 

PEER REVIEWED WORKSHOPS/PRESENTATIONS:
Local
Hannah DF, Panetti TS, Mosher DF., Lysophospholipid induced endothelial cell migration: the role of extracellular matrix proteins and vascular endothelial cell growth factor, Mini-Symposium: Cell Signaling and Growth Control, Madison, Wisconsin, 06/2000
Hannah DF, Kamp TJ., Identification of human embryonic stems cells in infarcted mouse myocardium, University of Wisconsin Medical School Research Forum, Madison, Wisconsin, 08/2004
Wolfgram Dawn, Intradialytic hemodynamic stability and functional status, Department of Medicine Research Retreat, Milwaukee, WI, 03/13/2015
Wolfgram DF, Marconnect K, Intradialytic hemodynamics and cerebral perfusion, Department of Medicine Research Retreat, Milwaukee, WI, 03/10/2017
Richerson W, Schmit B, Wolfgram D, Changes in Cerebral White Matter Integrity in Hemodialysis Patients, Department of Medicine Research Retreat, Milwaukee, WI, 03/06/2020
 
Regional
Hannah DF, Rhabdomyolysis on an 82 year old man on lipid lowering therapy, American College of Physicians Wisconsin Chapter Annual Meeting, Milwaukee, WI, 10/2006
Wolfgram DF, Pre-dialysis fluid overload is an important predictor of renal recovery in patients with acute kidney injury requiring renal replacement therapy, Midwest Nephrology Fellow's Conference, Chicago, Illinois, 10/2010
 
National
Wolfgram DF, Song P, Hu Y, Kommareddi M, Heung M., The association between fluid overload and recovery of renal function in acute kidney injury, National Kidney Foundation. Spring Clinical Meeting, Las Vegas, Nevada, 06/2011
Wolfgram DF, Foster D, Schlageter K, Wilkinson S, Jorgenson L Jones L, Astor BC, Chan M, Risk factors associated with development of clostridium difficle colitis in peritoneal dialysis patients with peritonitis, Annual Dialysis Conference, St. Louis, Missouri, 03/2012
 
International
Wolfgram DF, Song, P, Hu Y, Heung M, Predictors of dialysis independence in patients with acute kidney injury requiring renal replacement therapy, American Society of Nephrology Annual Meeting, San Diego, California, 11/2009
Wolfgram DF, Astor BC, Gundo V, Jhagroo RA, Standard dose hydrochlorothiazide is associated with less urinary calcium reduction compared to chlorthalidone, American Society of Nephrology, San Diego, California, 11/2012
Wolfgram DF, Szabo, A, Murray AM, Whittle J., Differences in incidence of dementia based on dialysis modality, American Society of Nephrology Annual Meeting, Atlanta, Georgia, 11/2013
Wolfgram DF, Marconnect K, Intradialytic hemodynamics and cerebral perfusion, American Society of Nephrology Annual Meeting, New Orleans, LA, 11/03/2017
Wolfgram DF, Richerson W, Veenedaal C, Schmit B., Intradialytic Cerebral Perfusion and Cognitive Outcomes in Older Adults on Hemodialysis, American Society of Nephrology, Washington, DC, 11/07/2019
 

COMMITTEE SERVICE:
Medical College of Wisconsin
06/2013 - Present Member, Key Clinical Faculty, Nephrology, Medicine, Medical College of Wisconsin
07/2013 - Present Interviewer, Internal Medicine Selection Committee, Medicine, Medical College of Wisconsin
09/2013 - 01/2017 Member, Program Evaluation Committee, Medicine, Medical College of Wisconsin
09/2013 - Present Member, Clinical Competency Commitee, Nephrology, Medicine, Medical College of Wisconsin
07/2017 - Present Member, Council for Women's Advocacy, Medical College of Wisconsin
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Student Education
11/2012 - 11/2018 M2 Renal lectures: Kidney Pathology and Clincial Correlations 1/year
10/25/2019 Kidney Stones
 
Resident and Fellow Education
01/2013 Clinical Pathological Correlation Case
01/2013 - Present Geriatric Nephrology Curriculum for Fellows
03/2013 - Present Nephrology Journal Club for Fellows
09/2014 Resident Journal Club
06/2016 - Present Attend VA noon report 1-2/month
07/2016 - Present Peritoneal Dialysis Curriculum for Fellows
03/2017 - Present Resident Academic Half Day: Nephrology Lectures 1-2 per year
 

EXTRAMURAL TEACHING:
Resident and Fellow Education
01/2013 - Present Zablocki VA Medical Center, Attending on nephrology consult service 3 months per year
01/2013 - 01/2015 Zablocki VA Medical Center, Attending for general medicine ward. 0.5-1 month per year
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
David Holzer, Medical College of Wisconsin, 05/28/2018 - 08/10/2018 Research Supervisor, Poster at MSSRP Research Day
 
Clinical/Research Fellows
Kristine Sunio, Medical College of Wisconsin, 07/2013 - 12/2013 Mentored fellow research project, published paper
Zubin Lathara, Medical College of Wisconsin, 07/2014 - 12/2014 Mentored fellows research project, published paper
Naveet Bal, Medical College of Wisconsin, 11/01/2016 - 06/30/2017 Mentored Fellow Research Project
 

PROGRAMMATIC DEVELOPMENTS:
 
 
Clinical Programs
05/2019 Implementation of VA Peritoneal Dialysis Program
 
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Panetti TS, Hannah DF, Avraamides C, Gaughan JP, Marcinkiewicz C, Huttenlocher A, Mosher DF. Extracellular matrix molecules regulate endothelial cell migration stimulated by lysophosphatidic acid. J Thromb Haemost. 2004 Sep;2(9):1645-56.
2. Heung M, Wolfgram DF, Kommareddi M, Hu Y, Song PX, Ojo AO. Fluid overload at initiation of renal replacement therapy is associated with lack of renal recovery in patients with acute kidney injury. Nephrol Dial Transplant. 2012 Mar;27(3):956-61. PMCID: PMC3471547
3. Wolfgram DF, Foster D, Astor BC, Chan MR. Development of Clostridium difficile colitis in peritoneal dialysis patients treated for peritonitis. Perit Dial Int. 2012 Nov-Dec;32(6):666-8. PMCID: PMC3524895
4. Wolfgram DF, Gundu V, Astor BC, Jhagroo RA. Hydrochlorothiazide compared to chlorthalidone in reduction of urinary calcium in patients with kidney stones. Urolithiasis. 2013 Aug;41(4):315-22.
5. Wolfgram DF, Sunio L, Vogt E, Smith HM, Visotcky A, Laud P, Whittle J. Haemodynamics during dialysis and cognitive performance. Nephrology (Carlton). 2014 Dec;19(12):771-6. PMCID: PMC4452995
6. Wolfgram DF, Szabo A, Murray AM, Whittle J. Risk of dementia in peritoneal dialysis patients compared with hemodialysis patients. Perit Dial Int. 2015 Mar-Apr;35(2):189-98. PMCID: PMC4406314
7. Wolfgram D, Vogt E, Jahn AL, Smith HM, Sussman J, Visotcky A, Laud P, Whittle J. Hemodynamics During Dialysis and Changes in Cognitive Performance. WMJ. 2016 12;115(6):311-6.
8. Wolfgram DF, Lathara Z, Szabo A, Whittle J. Dialytic hemodynamics are associated with changes in gait speed. Hemodial Int. 2017 10;21(4):566-574. PMCID: PMC5440226
9. Wolfgram DF, Garcia K, Evans G, Zamanian S, Tang R, Wiegmann T, Sharma R, Campbell R, Whittle J, SPRINT Study Research Group. Association of Albuminuria and Estimated Glomerular Filtration Rate with Functional Performance Measures in Older Adults with Chronic Kidney Disease. Am J Nephrol. 2017;45(2):172-179.
10. Cheung AK, Rahman M, Reboussin DM, Craven TE, Greene T, Kimmel PL, Cushman WC, Hawfield AT, Johnson KC, Lewis CE, Oparil S, Rocco MV, Sink KM, Whelton PK, Wright JT Jr, Basile J, Beddhu S, Bhatt U, Chang TI, Chertow GM, Chonchol M, Freedman BI, Haley W, Ix JH, Katz LA, Killeen AA, Papademetriou V, Ricardo AC, Servilla K, Wall B, Wolfgram D, Yee J, SPRINT Research Group. Effects of Intensive BP Control in CKD. J Am Soc Nephrol. 2017 Sep;28(9):2812-2823. PMCID: PMC5576945
11. Rocco MV, Sink KM, Lovato LC, Wolfgram DF, Wiegmann TB, Wall BM, Umanath K, Rahbari-Oskoui F, Porter AC, Pisoni R, Lewis CE, Lewis JB, Lash JP, Katz LA, Hawfield AT, Haley WE, Freedman BI, Dwyer JP, Drawz PE, Dobre M, Cheung AK, Campbell RC, Bhatt U, Beddhu S, Kimmel PL, Reboussin DM, Chertow GM, SPRINT Research Group. Effects of Intensive Blood Pressure Treatment on Acute Kidney Injury Events in the Systolic Blood Pressure Intervention Trial (SPRINT). Am J Kidney Dis. 2018 03;71(3):352-361. PMCID: PMC5828778
12. Wolfgram DF. Filtering the Evidence: Is There a Cognitive Cost of Hemodialysis? J Am Soc Nephrol. 2018 04;29(4):1087-1089. PMCID: PMC5875964
13. Wolfgram DF. Intradialytic Cerebral Hypoperfusion as Mechanism for Cognitive Impairment in Patients on Hemodialysis. J Am Soc Nephrol. 2019 11;30(11):2052-2058. PMCID: PMC6830804
14. Sturgill D.A, Bal N, Nagavally S, Wolfgram D.F. The Relationship between Dialysis Metrics and Patient-Reported Cognition, Fatigue, and Physical Function Kidney Dis. DOI:10.1159/000508919.
15. Richerson WT, Umfleet LG, Schmit BD, Wolfgram DF. Changes in Cerebral Volume and White Matter Integrity in Adults on Hemodialysis and Relationship to Cognitive Function. Nephron. 2020 Oct 13:1-9.
16. Rapp SR, Gaussoin SA, Sachs BC, Chelune G, Supiano MA, Lerner AJ, Wadley VG, Wilson VM, Fine LJ, Whittle JC, Auchus AP, Beddhu S, Berlowitz DR, Bress AP, Johnson KC, Krousel-Wood M, Martindale-Adams J, Miller EC, Rifkin DE, Snyder JK, Tamariz L, Wolfgram DF, Cleveland ML, Yang M, Nichols LO, Bryan RN, Reboussin DM, Williamson JD, Pajewski NM, SPRINT Research Group. Effects of intensive versus standard blood pressure control on domain-specific cognitive function: a substudy of the SPRINT randomised controlled trial. Lancet Neurol. 2020 11;19(11):899-907.
 

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