CURRICULUM VITAE
Ellis D. Avner MD
Ellis D. Avner MD
Professor
Department of Pediatrics
Division of Nephrology
Department of Pediatrics
Division of Nephrology
OFFICE ADDRESS: |
Translational and Biomedical Research Center |
8701 Watertown Plank Rd |
Milwaukee, WI 53226 |
EDUCATION: |
1966 - 1970 A. B. Princeton University, Princeton, NJ |
1966 - 1970 AB - Religion, Princeton University, Princeton, NJ |
1971 - 1975 M.D. University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania |
1971 - 1975 MD, University of Pennsylvania School of Medicine, Philadelphia, PA |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
1975 - 1978 Internship/Residency, Pediatrics, (PL1-PL3), Children's Hospital, Boston, MA |
1975 - 1978 Internship/Residency, Children's Hospital; Boston, Massachusetts |
1978 - 1980 Fellowship, Children's Hospital, Pediatric Nephrology, Boston, MA |
1978 - 1980 Fellowship, Children's Hospital, Human Reproduction and Reproductive Biology, Boston, MA |
1978 - 1980 Fellowship, Pediatric/Nephrology, Children's Hospital, Boston, MA |
1978 - 1980 Laboratory of Human, Developmental Biology, Reproduction and Reproductive Biology, Boston, MA |
APPOINTMENTS AND POSITIONS |
APPOINTMENTS AND POSITIONS |
APPOINTMENTS AND POSITIONS |
MILITARY SERVICE: |
None |
FACULTY APPOINTMENTS: |
07/01/1980 - 06/30/1986 Assistant Professor, Pediatrics, Nephrology, University of Pittsburgh School of Medicine, Pittsburgh, PA |
1980 - 1986 Assistant Professor, Pediatrics, University of Pittsburgh School of Medicine |
07/01/1986 - 06/30/1988 Associate Professor, Pediatrics, Nephrology, University of Pittsburgh School of Medicine, Pittsburgh, PA |
1986 - 1988 Associate Professor, Pediatrics, University of Pittsburgh School of Medicine |
11/01/1988 - 06/30/1995 Professor, Pediatrics, Nephrology, University of Washington School of Medicine, Seattle, WA |
1988 - 1995 Professor, Pediatrics, University of Washington School of Medicine |
07/01/1995 - 06/30/2004 Gertrude Lee Chandler Tucker Professor and Chairman, Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH |
1995 - 2004 Gertrude Lee Chandler Tucker Professor and Chairman, Department of Pediatrics |
07/01/2004 - 03/01/2015 Professor, Pediatrics, Nephrology, Medical College of Wisconsin, Milwaukee, WI |
07/01/2004 - 03/01/2015 Associate Dean for Research, Medical College of Wisconsin, Milwaukee, WI |
2004 - 2012 Associate Dean for Research, Medical College of Wisconsin |
2004 - 2015 Professor, Pediatrics (Nephrology), Medical College of Wisconsin |
2004 - 2005 Adjunct Professor, Case Western Reserve University School of Medicine |
07/01/2007 - 03/01/2015 Professor, Physiology, Medical College of Wisconsin, Milwaukee, WI |
07/01/2007 - 03/15/2015 Co-Director, Clinical and Translational Science Institute, Medical College of Wisconsin, Milwaukee, WI |
2007 - 2015 Professor, Physiology, Medical College of Wisconsin |
2007 - 2011 Co-Director, Clinical and Translational Science Institute, Medical College of Wisconsin |
07/01/2008 - 03/01/2015 Adjunct Professor, Health Sciences, Marquette University, Milwaukee, WI |
07/01/2008 - 03/01/2015 Adjunct Professor, Marine and Freshwater Biomedical Sciences, University of Wisconsin, Milwaukee, Milwaukee, WI |
2008 - 2015 Marine and Freshwater Biomedical Sciences Center (MFBSC) Affiliate of the Great Lakes Water Institute, University of Wisconsin, Milwaukee |
2008 - 2015 Adjunct Professor, Marquette University, Milwaukee, Wisconsin |
07/01/2009 - 03/01/2015 Adjunct Professor, Electrical Engineering and Computing, Milwaukee School of Engineering, Milwaukee, WI |
03/01/2015 - Present Emeritus Professor, Pediatrics and Physiology, Nephrology, Medical College of Wisconsin, Milwaukee, WI |
2015 - Present Emeritus Professor, Pediatrics and Physiology, Medical College of Wisconsin |
Case Western Reserve University School of Medicine |
ADMINISTRATIVE APPOINTMENTS: |
1982 - 1988 Utilization Review Committee, Children's Hospital of Pittsburgh |
1983 - 1988 Resident Selection Committee, Children's Hospital of Pittsburgh |
1983 - 1988 Animal Research and Care Committee, Children's Hospital of Pittsburgh |
1984 - 1988 Chairman, Animal Research and Care Committee, Children's Hospital of Pittsburgh |
1985 - 1988 Chairman, Resident Selection Committee, Children's Hospital of Pittsburgh |
1986 - 1988 Research Advisory Committee, Children's Hospital of Pittsburgh |
1986 - 1988 Career Counseling Committee, University of Pittsburgh School of Medicine |
1986 - 1988 Career Counseling Committee, University of Pittsburgh School of Medicine |
1987 - 1988 Vice-Chairman, Research Advisory Committee, Children's Hospital of Pittsburgh |
1988 - 1995 Director, Seattle, Division of Nephrology, Children's Hospital and Medical Center |
1989 - 1995 Resident Selection Committee, Children's Hospital & Medical Center |
1989 - 1995 Research Advisory Committee, Children's Hospital and Medical Center |
1990 - 1995 Executive Committee on Transplantation, Children's Hospital and Medical Center |
1990 - 1992 Chronic Care Task Force, Children's Hospital and Medical Center |
1991 - 1993 Committee on Issues in Biomedical Research Integrity, University of Washington |
1991 - 1995 Faculty Council on Scientific Affairs, University of Washington |
1991 - 1995 Faculty Senator, University of Washington |
1991 - 1993 Committee on Issues in Biomedical Research Integrity, University of Washington |
1991 - 1995 Faculty Senator, University of Washington |
1991 - 1995 Faculty Council on Scientific Affairs, University of Washington |
1991 - 1994 Chairman, Animal Care and Use Committee, Children's Hospital and Medical Center |
1992 - 1995 Regular Lecturer, Pediatrics 512P: Seminars in Human Embryology and Teratology |
1992 - 1995 Regular Lecturer, Pediatrics 512P: Seminars in Human Embryology and Teratology |
1993 - 1995 Chairman, Fellowship Funding Committee Children's Hospital and Medical Center |
1993 - 1995 Contracts Committee, Children's University Medical Group |
1993 - 1995 Quality Improvement/Peer Review Committee, Children's Hospital and Medical Center |
1993 - 1995 Managed Care Committee, Department of Medicine, Children's Hospital and Medical |
1994 - 2004 Co-Chair, Reaggregation Design Team, Children's Hospital and Medical Center |
1994 - 1995 Regional Outreach Task Force, Children's Hospital and Medical Center |
1995 - 2004 Member, Executive Committee, Case Western Reserve University School of Medicine |
1995 - 2004 Chairman, Children's Research Foundation, Cleveland, Ohio |
1995 - 2004 Chairman, Children's Research Foundation |
1995 - 2004 Member, Executive Committee, Case Western Reserve University School of Medicine |
1995 - 2004 Director of Pediatrics, Rainbow Babies and Children's Hospital and University Hospitals of Cleveland |
1995 - 1998 Member, Board of Directors, University Faculty Practice Association, University Hospitals of Cleveland |
1995 - 2004 University Primary Care Physicians / University Faculty Practice Association Liaison Committee, University Hospitals of Cleveland |
1995 - 2004 Member, Council of Clinical Chairs, University Hospitals of Cleveland |
1995 - 2004 Executive Committee, Clinical Council, University Hospitals of Cleveland |
1995 - 2004 Member, Clinical Council, University Hospitals of Cleveland |
1995 - 2004 Member, Clinical Leadership Advisory Committee, University Hospitals of Cleveland |
1996 - 1998 Executive Committee, University Faculty Practice Association |
1996 - 2004 Member, Honorary Degree Committee, Case Western Reserve University |
1996 - 2002 Member, Strategic Planning Committee, Office of the Dean, Case Western Reserve University School of Medicine |
1996 - 2003 Member, Clinical Council Credentialing Subcommittee, University Hospitals of Cleveland |
1996 - 1998 Executive Committee, University Faculty Practice Association |
1996 - 2004 Member, Honorary Degree Committee, Case Western Reserve University |
1996 - 2002 Member, Strategic Planning Committee, Office of the Dean, Case Western Reserve University School of Medicine |
1997 - 2004 Member, Minority Faculty Development Committee, University Hospitals of Cleveland |
1997 - 1998 Chair, Department of Medicine Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Richard A. Walsh named Chairman, 1998) |
1997 - 1998 Chair, Department of Medicine Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Richard A. Walsh named Chairman, 1998) |
1998 - 2001 Member, Department of Reproductive Biology Chair Search Committee, Case Western Reserve University School of Medicine (Dr. James Liu named Chairman, 2001) |
1998 - 2004 Member, Tenure Compensation Committee, Case Western Reserve School of Medicine |
1998 - 2004 Member, Tenure Compensation Committee, Case Western Reserve School of Medicine |
1998 - 2003 Member, Internal Affiliation Committee, University Hospitals of Cleveland |
1998 - 2001 Member, Department of Reproductive Biology Chair Search Committee, Case Western Reserve University School of Medicine (Dr. James Liu named Chairman, 2001) |
1999 - 2001 Member, Department of Family Medicine Chair Search Committee, Case Western Reserve University School of Medicine (Dr. George Kikano named Chairman, 2001) |
1999 - 2004 Member, Program Advisory Committee, Howard Hughes Medical Institute Biomedical Research Support Program, Case Western Reserve University School of Medicine |
1999 - 2000 Chair, Department of Psychiatry Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Pedro Delgado named Chairman, 2000) |
1999 - 2001 Member, Faculty Council (University Hospitals of Cleveland representative), Case Western Reserve University School of Medicine |
1999 - 2004 Member, Program Advisory Committee, Howard Hughes Medical Institute Biomedical Research Support Program, Case Western Reserve University School of Medicine |
1999 - 2000 Chair, Department of Psychiatry Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Pedro Delgado named Chairman, 2000) |
1999 - 2001 Member, Faculty Council (University Hospitals of Cleveland representative), Case Western Reserve University School of Medicine |
1999 - 2001 Member, Department of Family Medicine Chair Search Committee, Case Western Reserve University School of Medicine (Dr. George Kikano named Chairman, 2001) |
1999 - 2004 Member, Ad Hoc Committee on Safety of Polyvinylchloride/Phthalates, University |
1999 - 2003 Policy Advisory Committee, Research Institute, University Hospitals of Cleveland |
1999 - 2003 Space Planning Committee, Research Institute, University Hospitals of Cleveland |
1999 - 2003 Member (Alternate), Executive Board, University Hospitals Faculty Services |
1999 - 2003 Member, Operational Advisory Committee, University Hospital Faculty Services |
1999 - 2004 Member, Mary B. Lee Endowment Fund Committee, University Hospitals of Cleveland |
2000 - 2003 Member, Conflict of Interest Policy Development Committee, University Hospitals Research Institute |
2000 - 2004 Member, Clinical Research Scholars Program Advisory Committee, Case Western |
2000 - 2004 Chair, Educational and Research Mission Workgroup, University Hospitals of Cleveland |
2000 - 2003 Member, Quality Monitoring Council, University Hospitals of Cleveland |
2000 - 2003 Member, Performance Indicators Advisory Committee, University Hospitals of Cleveland |
2000 - 2004 Member, CWRU/UHC Research and Intellectual Property Task Force, University Hospitals of Cleveland |
2000 - 2003 Member, Executive Committee, University Hospitals Research Institute |
2000 - 2004 Member, Clinical Research Scholars Program Advisory Committee, Case Western |
2001 - 2004 Co-Chair, Department of Pathology Chair Search Committee, Case Western Reserve University School of Medicine |
2001 - 2004 Member, Committee on Faculty Tenure, Case Western Reserve University School of |
2001 - 2004 Co-Chair, Department of Pathology Chair Search Committee, Case Western Reserve University School of Medicine |
2001 - 2004 Member, Medical Resource Management Steering Committee, University Hospitals of |
2001 - 2004 Chief Medical Officer, Rainbow Babies and Children's Hospital of University Hospitals of Cleveland Rainbow Babies and Children's Corporation Chair for Excellence in Pediatrics |
2001 - 2004 Member, Committee on Faculty Tenure, Case Western Reserve University School of |
2002 - 2003 Member, Faculty Partnering Committee, Case Western Reserve University |
2002 - 2004 Member, General Clinical Research Center Advisory Committee, Case Western Reserve University School of Medicine |
2002 - 2003 Member, Faculty Partnering Committee, Case Western Reserve University |
2002 - 2003 Member, Department of Orthopedics Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Randall Marcus named Chairman, 2003) |
2002 - 2003 Member, University Hospitals and Case Western Reserve University Affiliation Committee, University Hospitals of Cleveland |
2002 - 2003 Member, Department of Orthopedics Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Randall Marcus named Chairman, 2003) |
2002 - 2004 Member, General Clinical Research Center Advisory Committee, Case Western Reserve University School of Medicine |
2002 - 2003 Member, Blueprint for Change Committee (Rainbow Babies & Children's Hospital |
2003 - 2004 Chair (Executive Sponsor), and Member, Executive Steering Committee, Children's |
2003 - 2004 Member, Vice Dean for Research Advisory Committee, Case Western Reserve University School of Medicine |
2003 - 2004 Member, Vice Dean for Research Advisory Committee, Case Western Reserve University |
2004 - 2005 Chair, General Clinical Research Center Director, Search Committee, Medical College of Wisconsin (Dr. Theodore Kotchen named Director, 2005) |
2004 - 2015 Member, Dean's Council for Research, Medical College of Wisconsin |
2004 - 2008 Member, General Clinical Research Center Advisory Committee, Medical College of Wisconsin |
2004 - 2005 Chair, General Clinical Research Center Director, Search Committee, Medical College of Wisconsin (Dr. Theodore Kotchen named Director, 2005) |
2004 - Present Member, Dean's Council for Research, Medical College of Wisconsin |
2004 - 2008 Member, General Clinical Research Center Advisory Committee, Medical College of Wisconsin |
2004 - 2012 Founding Director, Children's Research Institute, Children's Hospital and Health System of Wisconsin |
2005 - 2015 Member, Foundation Grants & Awards Committee, Medical College of Wisconsin |
2005 - 2015 Member, Department of Pediatrics Promotions Committee, Medical College of Wisconsin |
2005 - 2015 Member, Internal Referral Committee, Medical College of Wisconsin |
2005 - 2015 Member, Clinical Research Scholars Selection Committee, Medical College of Wisconsin |
2005 - 2015 Internal Advisory Committee for the Cardiovascular Research Center, Medical College of Wisconsin |
2005 - Present Member, Internal Referral Committee, Medical College of Wisconsin |
2005 - Present Internal Advisory Committee for the Cardiovascular Research Center, Medical College of |
2005 - Present Bioinformatics Steering Committee, Medical College of Wisconsin |
2005 - Present Member, Foundation Grants & Awards Committee, Medical College of Wisconsin |
2005 - Present Member, Department of Pediatrics Promotions Committee, Medical College of Wisconsin |
2005 - Present Member, Clinical Research Scholars Selection Committee, Medical College of Wisconsin |
2005 - 2010 Bioinformatics Steering Committee, Medical College of Wisconsin |
2005 - 2012 Board of Directors, Foundation of the Children's Hospital and Health System of Wisconsin |
2005 - 2012 Member, Strategic Planning Committee, Children's Hospital and Health System Foundation |
2006 - 2012 Member, Medical College of Wisconsin, Research Core Evaluation Committee |
2006 - 2012 Member, Strategic Planning Research Task Force, Medical College of Wisconsin |
2006 - Present Member, Strategic Planning Research Task Force, Medical College of Wisconsin |
2006 - Present Member, Medical College of Wisconsin, Research Core Evaluation Committee |
2007 - 2015 Associate Director, Kidney Disease Center, Medical College of Wisconsin |
2007 - Present Associate Director, Kidney Disease Center, Medical College of Wisconsin |
2007 - 2015 Director, Multidisciplinary Translational Center for Childhood Polycystic Kidney Disease, Children's Hospital and Health System of Wisconsin |
2007 - 2012 Chair and Member, Children's Research Campaign Sub-Committee, Children's Hospital and Health System Foundation |
2008 - Present Member, Pediatrics Joint Task Force, Medical College of Wisconsin |
2008 - 2015 Member, Pediatrics Joint Task Force, Medical College of Wisconsin |
2009 - 2012 Dean's Research leadership Council, Medical College of Wisconsin |
2012 - 2015 Advisor, Children's Research Institute |
University of Washington |
Reserve University School of Medicine |
Medicine |
HOSPITAL ADMINISTRATIVE APPOINTMENTS |
Research Foundation / ECG Management Consultants Project |
Center, Seattle, WA |
Hospitals of Cleveland |
Cleveland |
Service Line), University Hospitals of Cleveland |
CLINICAL ADMINISTRATIVE APPOINTMENTS |
HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS: |
1982 - 1988 Utilization Review Committee, Children's Hospital of Pittsburgh |
1983 - 1988 Resident Selection Committee, Children's Hospital of Pittsburgh |
1983 - 1988 Animal Research and Care Committee, Children's Hospital of Pittsburgh |
1984 - 1988 Chairman, Animal Research and Care Committee, Children's Hospital of Pittsburgh |
1985 - 1988 Chairman, Resident Selection Committee, Children's Hospital of Pittsburgh |
1986 - 1988 Research Advisory Committee, Children's Hospital of Pittsburgh |
1987 - 1988 Vice-Chairman, Research Advisory Committee, Children's Hospital of Pittsburgh |
1988 - 1995 Director, Pediatrics, Division of Nephrology, Children's Hospital and Medical Center, Seattle, WA |
1989 - 1995 Research Advisory Committee, Children's Hospital and Medical Center |
1989 - 1995 Resident Selection Committee, Children's Hospital & Medical Center |
1990 - 1995 Executive Committee on Transplantation, Children's Hospital and Medical Center |
1990 - 1992 Chronic Care Task Force, Children's Hospital and Medical Center |
1991 - 1994 Chairman, Animal Care and Use Committee, Children's Hospital and Medical Center |
1993 - 1995 Contracts Committee, Children's University Medical Group |
1993 - 1995 Chairman, Fellowship Funding Committee Children's Hospital and Medical Center |
1993 - 1995 Quality Improvement/Peer Review Committee, Children's Hospital and Medical Center |
1993 - 1995 Managed Care Committee, Department of Medicine, Children's Hospital and Medical |
1994 - 2004 Co-Chair, Reaggregation Design Team, Children's Hospital and Medical Center |
1994 - 1995 Regional Outreach Task Force, Children's Hospital and Medical Center |
1995 - 1998 Member, Board of Directors, University Faculty Practice Association, University Hospitals of Cleveland |
1995 - 2004 Executive Committee, Clinical Council, University Hospitals of Cleveland |
1995 - 2004 Member, Clinical Leadership Advisory Committee, University Hospitals of Cleveland |
1995 - 2004 University Primary Care Physicians / University Faculty Practice Association Liaison Committee, University Hospitals of Cleveland |
1995 - 2004 Member, Council of Clinical Chairs, University Hospitals of Cleveland |
1995 - 2004 Member, Clinical Council, University Hospitals of Cleveland |
1995 - 2004 Director of Pediatrics, Rainbow Babies and Children's Hospital and University Hospitals |
1996 - 2003 Member, Clinical Council Credentialing Subcommittee, University Hospitals of Cleveland |
1997 - 2004 Member, Minority Faculty Development Committee, University Hospitals of Cleveland |
1998 - 2003 Member, Internal Affiliation Committee, University Hospitals of Cleveland |
1999 - 2004 Member, Ad Hoc Committee on Safety of Polyvinylchloride/Phthalates, University |
1999 - 2003 Member, Operational Advisory Committee, University Hospital Faculty Services |
1999 - 2004 Member, Mary B. Lee Endowment Fund Committee, University Hospitals of Cleveland |
1999 - 2003 Policy Advisory Committee, Research Institute, University Hospitals of Cleveland |
1999 - 2003 Member (Alternate), Executive Board, University Hospitals Faculty Services |
1999 - 2003 Space Planning Committee, Research Institute, University Hospitals of Cleveland |
2000 - 2003 Member, Executive Committee, University Hospitals Research Institute |
2000 - 2003 Member, Conflict of Interest Policy Development Committee, University Hospitals Research Institute |
2000 - 2004 Member, CWRU/UHC Research and Intellectual Property Task Force, University Hospitals of Cleveland |
2000 - 2003 Member, Performance Indicators Advisory Committee, University Hospitals of Cleveland |
2000 - 2003 Member, Quality Monitoring Council, University Hospitals of Cleveland |
2000 - 2004 Chair, Educational and Research Mission Workgroup, University Hospitals of Cleveland |
2001 - 2004 Chief Medical Officer, Rainbow Babies and Children's Hospital of University Hospitals of Cleveland Rainbow Babies and Children's Corporation Chair for Excellence in Pediatrics |
2001 - 2004 Member, Medical Resource Management Steering Committee, University Hospitals of |
2002 - 2003 Member, University Hospitals and Case Western Reserve University Affiliation Committee, University Hospitals of Cleveland |
2002 - 2003 Member, Blueprint for Change Committee (Rainbow Babies & Children's Hospital |
2003 - 2004 Chair (Executive Sponsor), and Member, Executive Steering Committee, Children's |
2004 - Present Director, Children's Research Institute, Children's Hospital and Health System of Wisconsin |
2005 - Present Member, Strategic Planning Committee, Children's Hospital and Health System Foundation |
2007 - Present Director, Polycystic Kidney Disease Clinic, Children's Hospital and Health System of Wisconsin |
2007 - Present Chair and Member, Children's Research Campaign Sub-Committee, Children's Hospital and Health System Foundation |
RESEARCH ADMINISTRATIVE APPOINTMENTS: |
1987 - Present Member, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1987 - Present Member, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1989 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1989 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1990 - Present Member, Ad-Hoc Scientific Study Section NIDDK (Diabetic Nephropathy) |
1990 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1990 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1990 - Present Member, Ad-Hoc Scientific Study Section NIDDK (Diabetic Nephropathy) |
1991 - Present Ad-Hoc Member, General Medicine B Study Section, NIDDK |
1991 - 1995 Regular Member, General Medicine B Study Section, NIDDK |
1991 - Present Ad-Hoc Member, General Medicine B Study Section, NIDDK |
1991 - 1995 Regular Member, General Medicine B Study Section, NIDDK |
1992 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development, Polycystic Kidney Disease) |
1992 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development, Polycystic Kidney Disease) |
1993 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development) |
1993 - 1995 Chairman, General Medicine B Study Section, NIDDK |
1993 - 1995 Chairman, General Medicine B Study Section, NIDDK |
1993 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development) |
1995 - 1996 Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1995 - 1999 Member, National Institutes of Health Reviewers Reserve |
1995 - 1996 Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1995 - 1999 Member, National Institutes of Health Reviewers Reserve |
2000 - 2001 Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
2000 - 2001 Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
2002 - Present Member, Committee on Scientific Study Section Reorganization, NIDDK |
2002 - Present Member, Committee on Scientific Study Section Reorganization, NIDDK |
2002 - Present Chairman, Ad-Hoc Scientific Study Section, NIAID (Cooperative Clinical Trial in Pediatric Transplantation) |
2002 - Present Chairman, Ad-Hoc Scientific Study Section, NIAID (Cooperative Clinical Trial in Pediatric Transplantation) |
2004 - 2015 Ad- Hoc Member, Kidney Development and Urology Study Section, NIDDK |
2004 - Present Ad- Hoc Member, Kidney Development and Urology Study Section, NIDDK |
2005 - Present Ad-Hoc Member, Intercellular Interactions Study Section, NIH |
2005 - 2015 Ad-Hoc Member, Intercellular Interactions Study Section, NIH |
2008 - Present Ad-Hoc Reviewer, National Children's Study Adjunct Studies, NICHD |
2008 - 2015 Ad-Hoc Reviewer, National Children's Study Adjunct Studies, NICHD |
2009 - Present Ad-Hoc Reviewer, Kidney Development and Urology Study Section, NIDDK |
2009 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
NATIONAL INSTITUTES OF HEALTH PEER-REVIEW |
HOSPITAL STAFF PRIVILEGES: |
1980 - 1988 Staff Nephrologist, Children's Hospital of Pittsburgh, Pittsburgh, PA |
1980 - 1988 Staff Nephrologist, Children's Hospital of Pittsburgh |
1988 - 1995 Director, Division of Nephrology, Children's Hospital and Medical Center, Seattle, WA |
1988 - 1995 Staff Nephrologist, Children's Hospital Medical Center, Seattle |
1988 - 1995 Staff Nephrologist, Seattle Children's Hospital |
1995 - 2004 Staff Nephrologist, Rainbow Babies and Children's Hospital |
1995 - 2004 Director of Pediatrics, Rainbow Babies and Children’s Hospital and University Hospitals, Cleveland, OH |
1995 - 2004 Staff Nephrologist, Rainbow Babies and Children's Hospital, Cleveland |
2001 - 2004 Chief Medical Officer, Rainbow Babies and Children’s Hospital of University Hospitals, Cleveland, OH |
2004 - 2015 Staff Nephrologist, Children's Hospital of Wisconsin |
2004 - 2015 Staff Nephrologist, Children's Hospital of Wisconsin |
2004 - 2012 Founding Director, Rainbow Babies and Children’s Hospital of University Hospitals, Children’s Research Institute, Children’s Hospital and Health System of Wisconsin, Milwaukee, WI |
2004 - Present Attending Physician, Division of Nephrology, Children’s Hospital and Health System of Wisconsin |
2007 - Present Director, Polycystic Kidney Disease Program, Children’s Hospital and Health System of Wisconsin, Milwaukee, WI |
SPECIALTY BOARDS AND CERTIFICATION: |
Certificates | Issued By | Issue Date | Expiration |
National Board of Medical Examiners | 1976 | None | |
American Board of Pediatrics | 1980 | None | |
Sub-Board of Pediatric Nephrology, American Board of Pediatrics | 1982 | None | |
Licensure | Number | Issue Date | Expiration |
State of Massachusetts Temporary Licensure | 1975 | 1980 | |
State of Pennsylvania Licensure | 1980 | 1988 | |
State of Washington Licensure | 1988 | 1995 | |
State of Montana Licensure | 1990 | None | |
State of Ohio Licensure | 1995 | 2005 | |
State of Wisconsin Licensure | 2004 | None | |
AWARDS AND HONORS: |
1970 - Present Potts Award in Biblical Scholarship, Princeton University |
1970 - Present Woodrow Wilson National Scholar |
1970 - Present Potts Award in Biblical Scholarship, Princeton University |
1970 - Present Magna Cum Laude, Princeton University |
1970 - Present Magna Cum Laude, Princeton University |
1970 - Present Woodrow Wilson National Scholar |
1974 - Present Alpha Omega Alpha Honor Medical Society |
1974 - Present Alpha Omega Alpha Honor Medical Society |
1975 - Present Spencer Morris Prize in Medicine, University of Pennsylvania School of Medicine |
1975 - Present Spencer Morris Prize in Medicine, University of Pennsylvania School of Medicine |
1982 - 1985 Basil O'Connor Research Award, March of Dimes National Birth Defects Foundation |
1982 - 1985 Basil O'Connor Research Award, March of Dimes National Birth Defects Foundation |
1984 - 1987 New Investigator Research Award, National Institutes of Health |
1984 - 1987 New Investigator Research Award, National Institutes of Health |
1986 - Present Award of Tenure, University of Pittsburgh School of Medicine |
1986 - 1992 Councilor, International Pediatric Nephrology Association |
1986 - Present Award of Tenure, University of Pittsburgh School of Medicine |
1986 - 1992 Councilor, International Pediatric Nephrology Association |
1988 - 1991 Councilor, Society for Pediatric Research |
1988 - 1991 Councilor, Society for Pediatric Research |
1990 - Present Award of Tenure, University of Washington School of Medicine |
1990 - Present Award of Tenure, University of Washington School of Medicine |
1994 - Present Best Doctors in America, Woodward/White, Inc. |
1994 - Present Kidney Research Aid Fund Award (Institute of Child Health, London, England) |
1994 - Present Best Doctors in America, Woodward/White, Inc. |
1994 - Present Kidney Research Aid Fund Award, Institute of Child Health, London, England |
1995 - Present Mitchell Rubin Award in Pediatric Nephrology, Children’s Hospital of Buffalo |
1995 - Present Councilor, American Society of Pediatric Nephrology |
1995 - Present Award of Tenure, Case Western Reserve University School of Medicine |
1995 - 1997 Councilor, American Society of Pediatric Nephrology |
1995 - Present Award of Tenure, Case Western Reserve University School of Medicine |
1995 - Present Mitchell Rubin Lectureship and Award for Contributions to Pediatric Nephrology |
1996 - Present David Cornfeld Award in Pediatric Nephrology, Children’s Hospital of Philadelphia |
1996 - Present David Cornfeld Lectureship and Award in Pediatric Nephrology (Children's Hospital |
1997 - Present Dean's Distinguished Lecturer, Wayne State University School of Medicine |
1997 - Present Elected Fellow, American Association for the Advancement of Science "For outstanding contributions to unraveling the mechanisms of human polycystic kidney disease" |
1997 - 2000 Secretary/Treasurer, American Society of Pediatric Nephrology |
1997 - Present Foreign Member, Kazakhstan Academy of Medical Sciences |
1997 - 2000 Assistant Secretary, International Pediatric Nephrology Association |
1997 - Present Dean's Distinguished Lecturer, Wayne State University School of Medicine |
1997 - 2000 Assistant Secretary, International Pediatric Nephrology Association |
1997 - Present Foreign Member, Kazakhstan Academy of Medical Sciences |
1997 - 2000 Secretary/Treasurer, American Society of Pediatric Nephrology |
1997 - Present Elected Fellow, American Association for the Advancement of Science "For outstanding contributions to unraveling the mechanisms of human polycystic kidney disease" |
2000 - 2002 President-Elect, American Society of Pediatric Nephrology |
2000 - 2002 President-Elect, American Society of Pediatric Nephrology |
2001 - 2012 America's Top Doctors, Castle Connolly Medical Ltd. |
2001 - Present Distinguished Service Award in Health Care Education, Royal National Lao University, Lao PDR |
2001 - 2007 Member, Standing Committee, International Pediatric Association |
2001 - 2002 America's Top Doctors, Castle Connolly Medical Ltd. |
2001 - 2007 Member, Standing Committee, International Pediatric Association |
2001 - Present Distinguished Service Award in Health Care Education, Royal National Lao University, Lao PDR |
2001 - 2003 Million Dollar Professor, Case Western Reserve University |
2001 - 2010 Councilor, International Pediatric Nephrology Association |
2001 - 2003 Million Dollar Professor, Case Western Reserve University |
2001 - Present Councilor, International Pediatric Nephrology Association |
2001 - 2007 Standing Committee, International Pediatric Association |
2001 - Present Jean Pouliot Award and Lectureship in Pediatric Research, Montreal, Canada |
2001 - Present The Jean Pouliot Award and Lectureship in Pediatric Research, Montreal, Canada |
2002 - 2004 President, American Society of Pediatric Nephrology |
2002 - Present March of Dimes Distinguished Lecturer, New York Academy of Medicine |
2002 - 2004 Rainbow Babies Corporation, Chair for Excellence in Pediatrics |
2002 - Present Juvenile Diabetes Foundation Award , Research Achievement |
2002 - Present Juvenile Diabetes Foundation Award for Research Achievement |
2002 - 2004 President, American Society of Pediatric Nephrology |
2002 - Present March of Dimes Distinguished Lecturer, New York Academy of Medicine |
2003 - Present Howard Mermelstein Memorial Lecture, Children's Hospital of Pittsburgh |
2003 - 2004 Honored Member, Lifetime Achievement Award, Strathmore' Who's Who |
2003 - 2004 Honored Member, Lifetime Achievement Award, Strathmore’s Who’s Who |
2003 - 2004 President, Council of American Kidney Societies |
2003 - Present Howard Mermelstein Memorial Lecture, Children's Hospital of Pittsburgh |
2003 - 2004 President, Council of American Kidney Societies |
2003 - 2004 Honored Member, Lifetime Achievement Award, Strathmore' Who's Who |
2004 - 2007 Member, Executive Committee, International Pediatric Association |
2004 - Present Award of Tenure, Medical College of Wisconsin |
2004 - 2007 Member, Executive Committee, International Pediatric Association |
2004 - Present Award of Tenure, Medical College of Wisconsin |
2008 Invited IPNA Plenary Lecture, ESPN Annual Meeting, Lyon, France |
2008 - Present Henry L. Barnett Award for Excellence in Clinical Care and Education in Pediatric Nephrology, American Academy of Pediatrics |
2008 - Present Invited IPNA Plenary Lecture, ESPN Annual Meeting, Lyon, France |
2008 - Present Henry L. Barnett Lifetime Achievement Award, American Academy of Pediatric |
2009 - Present America’s Top Doctors Award, Castle Connolly Medical Ltd. |
2010 - Present Outstanding MCW Medical Student Teaching Award, Physiology |
2010 - Present Outstanding Medical Student Teaching Award, Medical College of Wisconsin (Physiology) |
2012 “America’s Top Pediatricians”, Consumers Research Council of America |
2012 “ Leading Nephrologists in WI”, The International Association of Healthcare Professionals |
2013 “Leading Physicians in the World” , The International Association of Healthcare Professionals |
2013 - Present Named "Leading Physicians in the World", IAHCP |
2014 - Present Invited Presidential Plenary Speaker, Pediatric Academic Societies Annual Meeting |
2014 - Present Invited Presidential Plenary Speaker, Pediatric Academic Societies Annual Meeting |
2014 - Present Inaugural Invited Speaker, Demetrius Ellis M.D. Annual Lecture in Pediatric Nephrology, Children's Hospital of Pittsburgh |
2014 - Present Inaugural Speaker, "Demetrius Ellis M.D. Annual Lecture in Pediatric Nephrology" Children's Hospital of Pittsburgh |
2014 Invited Plenary Speaker, Pediatric Academic Societies Annual Meeting |
2016 - Present Founders' Award for Lifetime Achievements in Pediatric Nephrology, American Society of Pediatric Nephrology |
2016 - Present Educational Excellence Award for Lifetime Global Achievements as an Educator, International Society of Pediatric Nephrology |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
1980 - Present American Society of Pediatric Nephrology (Member) |
1980 - Present American Society of Nephrology |
1980 - Present American Society of Pediatric Nephrology |
1980 - Present American Society of Nephrology (Member) |
1980 - Present Society for In Vitro Biology |
1980 - Present Society for In Vitro Biology (Member) |
1981 - Present International Society of Nephrology |
1981 - Present International Society of Nephrology (Member) |
1981 - Present International Pediatric Nephrology Association (Member) |
1981 - Present International Pediatric Nephrology Association |
1982 - Present American Society of Transplant Physicians (Member) |
1982 - Present American Society of Transplant Physicians |
1983 - Present American Federation for Clinical Research (Member) |
1983 - Present American Federation for Clinical Research |
1983 - Present American Journal of Diseases of Children |
1984 - 1988 Midwest Society for Pediatric Research |
1984 - Present In Vitro Cellular and Developmental Biology |
1984 - 1988 Midwest Society for Pediatric Research (Member) |
1985 - Present Society for Pediatric Research (elected) |
1985 - Present Society for Pediatric Research (elected) |
1986 - Present Sigma Xi - Scientific Research Society of North America (elected) |
1986 - Present Journal of Clinical Investigation |
1986 - Present Pediatric Nephrology |
1986 - Present American Society for Cell Biology (Member) |
1986 - Present Sigma Xi - Scientific Research Society of North America (elected) |
1986 - 1988 Pittsburgh Pediatric Society (Member) |
1986 - 1988 Pittsburgh Pediatric Society |
1986 - Present American Society for Cell Biology |
1987 - Present Pediatric Research |
1988 - 1989 Western Society for Pediatric Research (Member) |
1988 - Present American Journal of Medical Genetics |
1988 - Present Kidney International |
1989 - Present Fellow (American Academy of Pediatrics) |
1989 - 1995 Washington State Medical Association |
1989 - 1995 King County Medical Society |
1989 - 1995 North Pacific Pediatric Society |
1989 - 1995 Northwest Renal Society |
1989 - Present Western Society for Pediatric Research |
1989 - Present American Academy of Pediatrics (Fellow) |
1989 - 1995 Washington State Medical Association (m) |
1989 - 1995 Northwest Renal Society (Member) |
1989 - 1995 King County Medical Society (Member) |
1989 - 1994 Western Society for Pediatric Research |
1989 - 1995 North Pacific Pediatric Society (Member) |
1990 - 1995 Northwest Transplantation Society (Member) |
1990 - 1995 Northwest Transplantation Society |
1990 - Present Growth, Development (and Aging) |
1990 - Present Journal American Society of Nephrology |
1991 - Present American Journal of Physiology |
1992 - Present New England Journal of Medicine |
1992 - 2008 Kidney International |
1993 - Present American Pediatric Society (elected) |
1993 - Present American Pediatric Society (elected) |
1993 - Present American Journal of Kidney Diseases |
1993 - Present Scanning Electron Microscopy |
1993 - 2004 Seminars in Nephrology |
1993 - 1997 Pediatric Nephrology |
1994 - Present Pediatric Pathology |
1994 - 1996 Transplant Chronicles |
1995 - Present American Journal of Pathology |
1995 - 2004 Northern Ohio Pediatric Society |
1995 - 2004 Association of Medical School Pediatric Department (Chairman) |
1995 - 2004 Association of Medical School Pediatric Department Chairman |
1995 - 2004 Northern Ohio Pediatric Society (Member) |
1995 - 1999 American Journal of Kidney Diseases |
1996 - Present Journal of Urology |
1996 - Present Human Molecular Genetics |
1996 - Present Journal of Pediatrics |
1997 - 2004 Assistant Editor (Basic Science) (Pediatric Nephrology) |
1997 - Present Pediatrics |
2000 - 2008 Cooperating Editor (Kidney and Homeostasis) (Cell and Tissue Research) |
2001 - Present American Journal of Transplantation |
2001 - 2005 Renal Physicians Association |
2001 - 2005 Renal Physicians Association (Member) |
2004 - 2009 Pediatric Nephrology |
2004 - 2010 Current Pediatric Reviews |
2004 - 2013 Pediatric Research Leaders Association (SPR and APS (elected)) |
2004 - 2012 Current Reviews in Pediatrics |
2005 - Present Asian Journal of Pediatric Practice |
2005 - 2011 Journal of the American Society of Nephrology |
2009 - Present Journal of Pediatric Sciences |
2010 - Present Adolescent Health (Medicine and Therapeutics) |
2014 - Present Nature Reviews in Nephrology |
2014 - Present Trends in Molecular Medicine |
EDITORSHIPS/EDITORIAL BOARDS/REVIEW |
Journal Reviewer |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorial Board |
1992 - 2008 Kidney International |
1993 - 1997 Pediatric Nephrology |
1993 - 2004 Seminars in Nephrology |
1994 - 1996 Transplant Chronicles |
1995 - 1999 American Journal of Kidney Diseases |
1997 - 2004 Assistant Editor (Basic Science), Pediatric Nephrology |
2000 - 2008 Cooperating Editor (Kidney and Homeostasis), Cell and Tissue Research |
2004 - Present Pediatric Nephrology |
2004 - Present Current Reviews in Pediatrics |
2004 - 2012 Journal of the American Society of Nephrology |
2004 - Present Current Pediatric Reviews |
2005 - Present 2005- Journal of the American Society of Nephrology |
2005 - Present Asian Journal of Pediatric Practice |
2009 - Present Journal of Pediatric Sciences |
2010 - Present Adolescent Health, Medicine and Therapeutics |
Journal Review |
1983 - Present American Journal of Diseases of Children |
1984 - Present In Vitro Cellular and Developmental Biology |
1986 - Present Pediatric Nephrology |
1986 - Present Journal of Clinical Investigation |
1987 - Present Pediatric Research |
1988 - Present American Journal of Medical Genetics |
1988 - Present Kidney International |
1990 - Present Growth, Development, and Aging |
1990 - Present Journal American Society of Nephrology |
1991 - Present American Journal of Physiology |
1992 - Present New England Journal of Medicine |
1993 - Present American Journal of Kidney Diseases |
1993 - Present Scanning Electron Microscopy |
1994 - Present Pediatric Pathology |
1995 - Present American Journal of Pathology |
1996 - Present Journal of Urology |
1996 - Present Human Molecular Genetics |
1996 - Present Journal of Pediatrics |
1997 - Present Pediatrics |
2001 - Present American Journal of Transplantation |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
1980 - 1988 Member, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania |
1980 - 1988 Medical Advisory Board, National Kidney Foundation of Western Pennsylvania |
1980 - 1988 Medical Advisory Board, National Kidney Foundation of Western Pennsylvania |
1980 - 1988 Medical Advisory Board, National Kidney Foundation of Western Pennsylvania |
1983 - 1988 Secretary, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania |
1983 - 1988 Secretary, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania |
1983 - 1988 Secretary, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania |
1983 - 1988 Secretary, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania |
1984 - 1988 Chair, Animal Research and Care Committee, Children’s Hospital of Pittsburgh |
1985 - 1988 Chair, Resident Selection Committee, Children's Hospital of Pittsburgh |
1986 - 1988 Member, Research Advisory Committee, Children's Hospital of Pittsburgh |
1987 - 1988 Vice-Chair, Research Advisory Committee, Children's Hospital of Pittsburgh |
1989 - 1995 Medical Advisory Board, Northwest Kidney Foundation |
1989 - 1995 Medical Advisory Board, Northwest Kidney Foundation |
1989 - 1995 Member, Resident Selection Committee, Children's Hospital & Medical Center, Seattle |
1989 - 1995 Member, Medical Advisory Board, Northwest Kidney Foundation |
1989 - 1995 Member, Research Advisory Committee, Children's Hospital and Medical Center, Seattle |
1989 - 1995 Medical Advisory Board, Northwest Kidney Foundation |
1990 - 1992 Member, Chronic Care Task Force, Children's Hospital and Medical Center, Seattle |
1990 - 1995 Board Member, Northwest Organ Procurement Agency |
1990 - 1995 Board Member, Northwest Organ Procurement Agency |
1990 - 1995 Board Member, Northwest Organ Procurement Agency |
1990 - 1995 Member, Executive Committee on Transplantation, Children's Hospital and Medical Center, Seattle |
1992 - 1995 Medical Advisory Board, Starlight Foundation of Western Washington |
1992 - 1995 Medical Advisory Board, Starlight Foundation of Western Washington |
1992 - 1995 Medical Advisory Board, Starlight Foundation of Western Washington |
2001 - 2004 Member, Committee on Faculty Tenure, Case Western Reserve University School of Medicine |
2001 - 2003 Board Member, University Genetics, Inc. |
2001 - 2004 Member, Executive Committee, Rainbow Circle of Friends, Rainbow Babies & Children's |
2001 - 2004 Co-Chair, Department of Pathology Chair Search Committee, Case Western Reserve University School of Medicine |
2001 - 2004 Member, Executive Committee, Rainbow Circle of Friends, Rainbow Babies & Children's |
2001 - 2003 Board Member, University Genetics, Inc. |
2001 - 2004 Member, Executive Committee, Rainbow Circle of Friends, Rainbow Babies & Children's |
2001 - 2003 Board Member, University Genetics, Inc. |
2002 - 2003 Member, Case Western Reserve University School of Medicine Chair Search Committee, Department of Orthopedics |
2002 - 2004 Member, Subcommittee for Rainbow Babies & Children's Hospital, University Hospitals |
2002 - 2004 Member, General Clinical Research Center Advisory Committee, Case Western Reserve University School of Medicine |
2002 - 2004 Member, Subcommittee for Rainbow Babies & Children's Hospital, University Hospitals |
2002 - 2003 Member, Faculty Partnering Committee, Case Western Reserve University |
2002 - 2004 Member, Subcommittee for Rainbow Babies & Children's Hospital, University Hospitals |
2003 - Present Member, Board of Directors, Kidney and Urology Foundation of America |
2003 - 2004 Member, Research Advisory Committee, Case Western Reserve University School of Medicine |
2003 - Present Member, Board of Directors, Kidney and Urology Foundation of America |
2003 - 2007 Member, Board of Directors, International Pediatric Association Corporation |
2003 - Present Member, Board of Directors, Kidney and Urology Foundation of America |
2003 - 2007 Member, Board of Directors, International Pediatric Association Corporation |
2003 - 2007 Member, Board of Directors, International Pediatric Association Corporation |
2004 - 2005 Chair, General Clinical Research Center Director, Search Committee, Medical College of Wisconsin |
2004 Member, Dean’s Council for Research, Medical College of Wisconsin |
2004 - 2008 Member, General Clinical Research Center Advisory Committee, Medical College of Wisconsin |
2005 Member, Bioinformatics Steering Committee, Medical College of Wisconsin |
2005 Member, Internal Advisory Committee for the Cardiovascular Research Center, Medical College of Wisconsin |
2005 Member, Foundation Grants & Awards Committee, Medical College of Wisconsin |
2005 Associate Director, Kidney Disease Center, Medical College of Wisconsin |
2005 Member, Department of Pediatrics Promotions Committee, Medical College of Wisconsin |
2005 Member, Clinical Research Scholars Selection Committee, Medical College of Wisconsin |
2005 - Present Member, Board of Directors, Foundation of the Children's Hospital and Health System of Wisconsin |
2005 - Present Member, Board of Directors, Foundation of the Children's Hospital and Health System of Wisconsin |
2005 - Present Member, Board of Directors, Foundation of the Children's Hospital and Health System of Wisconsin |
2006 Member, Strategic Planning Research Task Force, Medical College of Wisconsin |
2006 Member, Research Core Evaluation Committee, Medical College of Wisconsin |
2007 Associate Director, Kidney Disease Center, Medical College of Wisconsin |
2008 Member, Planning Committee, Foundation of the Children’s Hospital and Health System of Wisconsin |
2008 Member, Pediatrics Joint Task Force, Medical College of Wisconsin |
2009 - Present Member, Cardiovascular Center Scientific Advisory Committee, Medical College of Wisconsin |
2009 - 2011 Member and Program Lecturer, Summer Program Undergraduate Research Committee, Medical College of Wisconsin |
2009 Member, Dean’s Research Leadership Council, Medical College of Wisconsin |
2009 - 2011 Member and Program Lecturer, Summer Program Undergraduate Research Committee, Medical College of Wisconsin |
2010 Elected, National Representative, Clinical Translational Science Award (CTSA) Child Health Oversight Committee, Medical College of Wisconsin |
2010 - 2013 Member, Cardiovascular Center Scientific Advisory Committee, Medical College of Wisconsin |
2011 Member, Search Committee, Department of OB/GYN |
Hospital Board of Trustees |
of Cleveland Board of Trustees |
of Cleveland Board of Trustees |
Hospital Board of Trustees |
Hospital Board of Trustees |
of Cleveland Board of Trustees |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
1980 - 1988 Member, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania |
1985 - 1995 Member, Medical Advisory Board, Northwest Kidney Foundation |
1985 - 1988 Member, Scientific Program Committee, Midwest Society for Pediatric Research Annual Meeting |
1987 Member, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1987 Member, Committee on Transplantation, American Society of Pediatric Nephrology |
1987 Member, International Scientific Program Committee, Eighth Congress of the International Pediatric Nephrology Association |
1988 Member, International Advisory Committee, Fourth International Workshop on Developmental Renal Physiology |
1989 Invited Participant, Somatic Cell and Molecular Genetics Workshop, Eleanor Roosevelt Institute for Cancer Research and the National Cancer Institute |
1989 Chair, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1989 Member, Scientific Grant Proposal Review, March of Dimes Birth Defects Foundation |
1990 - 1995 Member, Advisory Committee on Organ Procurement, Pacific Northwest Organ Society |
1990 Member, Scientific Grant Proposal Review, Veteran's Health Services and Research Administration |
1990 - 1995 Consultant, Scientific Review, Medical Research Council of Canada (Polycystic Kidney Disease, Renal Growth Factors) |
1990 Scientific Advisor, Office for Research, University of Melbourne, Australia (Polycystic Kidney Disease) |
1990 Member, Ad-Hoc Scientific Study Section, NIDDK (Diabetic Nephropathy) |
1990 - 1995 Member, Board of Trustees, Northwest Organ Procurement Agency |
1990 Chair, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1991 Ad-Hoc Member, General Medicine B Study Section, NIDDK |
1991 - 1999 Member, Board of Scientific Advisors, Polycystic Kidney Research Foundation |
1991 - 1992 Member, Ad-Hoc Pediatric Committee, UNOS |
1991 - 1995 Member, General Medicine B Study Section, NIDDK |
1991 Member, International Organizing Committee, Fifth International Workshop on Developmental Renal Physiology |
1991 Member, NIH Planning Committee, Research and Training in Pediatric Nephrology |
1991 - 2000 Member, Research Committee, American Society of Pediatric Nephrology |
1992 Chair, Society for Pediatric Research Annual Meeting, Scientific Program (Nephrology) |
1992 - 1995 Member, Medical Advisory Board, Starlight Foundation of Western Washington |
1992 - 1997 Scientific Advisor, University of Colorado Center for the Study of Polycystic Kidney Disease |
1992 Scientific Advisor, Washington University Nephrology Center - Kidney Development |
1992 Chair, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development, Polycystic Kidney Disease) |
1992 - 1996 Member, Scientific Advisory Committee, North American Pediatric Renal Transplant Cooperative Study |
1992 Member, NIH Strategic Planning Committee (Pediatric Nephrology) |
1993 - 1999 Member, Pediatric Committee, American Society of Transplant Physicians |
1993 - 1999 Chair, Scientific Committee, International Study of Genetic Renal Diseases |
1993 - 1999 Member, Executive Committee, International Study of Genetic Renal Diseases |
1993 - 1999 Member, Scientific Advisory Committee, International Pediatric Nephrology Association |
1993 Member, Program Committee, Society for Pediatric Research Annual Meeting |
1993 Co-Chair, Program Committee, American Society of Nephrology Annual Meeting |
1993 Chair, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development) |
1993 - 1995 Chair, General Medicine B Study Section, NIDDK |
1994 - 1995 Member, Organizing Committee, 6th International Workshop on Developmental Nephrology |
1994 - 1995 Member, Scientific Program Committee, 10th Congress of the International Pediatric Nephrology Association |
1994 - 1995 Co-Chair, Pediatric Committee, American Society of Transplant Physicians |
1994 Scientific Reviewer, Wellcome Trust Grant Program (Molecular and Cell Biology) |
1995 - 1999 Member, National Institutes of Health Reviewers Reserve |
1995 Co-Chair, American Society of Nephrology Annual Meeting, Symposium on Renal Development/Differentiation |
1995 - 1998 Member, Peters and Scribner Awards Subcommittees, American Society of Nephrology |
1995 Member, Scientific Advisory Committee, Biomedical Research Cleveland |
1995 - 1996 Chair, Pediatric Committee, American Society of Transplant Physicians |
1995 Co-Chair, 10th Congress of the International Pediatric Nephrology Association, Symposium on Polycystic Kidney Disease |
1995 - 1996 Chair, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
1996 Chair, 1996 Basic Science Conference: Renal Developmental Biology, American Society of Nephrology |
1996 Co-Chair, Symposium on Disease Progression in Pediatric Chronic Renal Insufficiency, American Society of Pediatric Nephrology Annual Meeting |
1996 Member, Scientific Advisory Board, Center for Pediatric Research, Eastern Virginia Medical School |
1996 Member, Nominating Committee, American Society of Nephrology |
1997 Co-Chair, Symposium on Molecular Genetics and Renal Diseases, American Society of Pediatric Nephrology Annual Meeting |
1997 - 2005 Member, External Advisory Committee, Pediatric Nephrology Training Grant (T32-DK07662), University of Washington |
1997 - 1998 Member, Scientific Organizing Committee, 7th International Workshop on Developmental Nephrology |
1997 Moderator, , Free Communications Session on Recent Advances in Polycystic Kidney Disease, American Society of Pediatric Nephrology Annual Meeting |
1997 Chair, Task Force on Housestaff Recruitment, American Medical School Pediatric Department |
1997 - 1998 Member, Scientific Program Committee, 11th Congress of International Pediatric Nephrology Association |
1998 - 2001 Co-Chair, Scientific Program Committee, 12th Congress of International Pediatric Nephrology Association |
1998 - 2001 Member, National Organizing Committee, 12th Congress of International Pediatric Nephrology Association |
1998 Member, Strategic Planning Committee, NIH-Polycystic Kidney Disease Ad Hoc Advisory Committee |
1998 Member, Scientific Review Committee (Polycystic Kidney Disease), American Society of Nephrology Annual Meeting |
1998 Co-Chair, NIH-American Society of Nephrology Strategic Planning Committee, Renal Research Priorities: Growth, Development, Angiogenesis and Neoplasia |
1999 Member, NIH-American Society of Pediatric Nephrology Strategic Planning Committee, Research Priorities |
1999 - 2001 Member, Organizing Committee, 8th Annual International Workshop on Developmental Nephrology |
1999 Member, Executive Committee, NIH-American Society of Nephrology Strategic Planning Committee on Renal Research Priorities |
2000 - 2001 Chair, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease) |
2000 - 2004 Member, Program Planning Committee, Pediatric Academic Societies |
2000 - 2004 Member, Council of American Kidney Societies |
2001 - 2004 Member, Scientific Program Committee, The Thirteenth Congress of the International Pediatric Nephrology Association |
2001 - 2004 Board of Trustees, Executive Committee, Rainbow Circle of Friends, Rainbow Babies & Children’s Hospital |
2001 Co-Chair, Molecular Control of Renal Disease, 8th International Workshop: Developmental Nephrology, Victoria, British Columbia |
2001 Co-Chair, Polycystic Renal Disease in Pediatrics, 12th International Congress of Pediatric Nephrology, Seattle, Washington |
2001 - 2003 Member, Board of Trustees, University Genetics, Inc. |
2002 Session Chair, FASEB Conference: Molecular Mechanisms and Therapeutic Insights into PKD. Tucson, Arizona, ARPKD: Molecular Mechanisms in Pathogenesis of ARPKD |
2002 Member, External Scientific Advisory Committee, NIH Pediatric Scientist Training Program, Department of Pediatrics, Indiana University |
2002 Member, Senior Scholars Committee, American Pediatric Society |
2002 Co-Moderator, American Society of Pediatric Nephrology Annual Meeting, Baltimore, Maryland, Symposium on Cancer, Blood and the Kidney: Common Themes |
2002 - 2004 Board of Trustees, Subcommittee for Rainbow Babies & Children’s Hospital, University Hospitals of Cleveland, Rainbow Babies & Children’s Hospital |
2002 Member, Committee on Scientific Study Section Reorganization, NIDDK |
2002 Chair, Ad-Hoc Scientific Study Section, NIAID (Cooperative Clinical Trial in Pediatric Transplantation) |
2002 Co-Moderator, American Society of Nephrology Annual Meeting, Philadelphia, Pennsylvania, Symposium on PKD: New Genes and Mechanisms |
2002 Co-Moderator, American Society of Pediatric Nephrology Annual Meeting, Baltimore, Maryland, Symposium on Molecular Basis of Renal Development and Disease |
2003 Member, Nominating Committee, North American Pediatric Renal Transplant Cooperative Study |
2003 - 2004 Member, Nominating Committee, American Society of Nephrology |
2003 President, Council of American Kidney Societies |
2003 Co-Chair, Plenary Symposium, Pediatric Solid Organ Transplantation in the 21st Century, Pediatric Academic Societies Annual Meeting, Seattle, Washington |
2003 - 2004 Member, Scientific Program Committee, American Society of Nephrology, 2004 Annual Meeting |
2003 - 2007 Member, Board of Directors, International Pediatric Association Corporation |
2003 Member, Board of Directors, Kidney and Urology Foundation of America |
2004 - 2007 Member, Scientific Program Committee, 14th Congress of the International Pediatric Nephrology Association |
2004 Chair, Basic Science Symposium, Non-mammalian Models of Renal Development/Disease, American Society of Nephrology, 2004 Annual Meeting |
2004 Ad- Hoc Member, Kidney Development and Urology Study Section, NIDDK |
2004 - 2007 Member, Scientific Program Committee, 25th International Congress of the International Pediatric Association, Athens, Greece |
2004 Chair, Plenary Symposium, Common Urinary Tract Problems in Children, The 24th Congress of the International Pediatric Association |
2005 - 2010 Member, Nominations Committee, American Society of Pediatric Nephrology |
2005 Board of Directors, Foundation of the Children’s Hospital and Health System of Wisconsin |
2005 - 2007 Member, Finance and Development Committee, International Pediatric Association |
2005 - 2007 Member, 2005-2007 Awards, Research and Development Committee, American Society of Pediatric Nephrology |
2005 Ad-Hoc Member, Intercellular Interactions Study Section, NIH |
2005 - 2012 Member, Board of Directors, Foundation of the Children’s Hospital and Health System of Wisconsin |
2007 Chair, Scientific Advisory Board, Calesta Pharmaceuticals |
2007 - 2010 Member, Scientific Program Committee, 15th Congress of the International Pediatric Nephrology Association |
2007 - 2012 Member, External Scientific Advisory Committee, University of Texas Southwestern O’Brien Kidney Center |
2007 Moderator, Plenary Symposium: New Approaches to UTI-VUR, 25th International Congress of Pediatrics, Athens, Greece |
2007 Moderator, IPNA Symposium: Update on Common Childhood Kidney Problems, 25th International Congress of Pediatrics, Athens, Greece |
2008 Co-Director, 2nd Gerry Schwartz and Heather Reisman International Congress on Children with Chronic Diseases |
2008 Elected Member, Adjunct Studies Review Committee, National Children’s Study, NICHD |
2008 Ad-Hoc Reviewer, National Children’s Study Adjunct Studies, NICHD |
2009 Ad-Hoc Reviewer, Kidney Development and Urology Study Section, NIDDK |
2009 Member, Professional Advisory Board, ARPKD/CHF Alliance |
2009 - Present Member, Board of Directors, Autosomal Recessive Polycystic Kidney Disease- Congenital Hepatic Fibrosis Alliance |
2009 - Present Member, Student/Laboratory Selection Committee and Program Lecturer, Summer Program Undergraduate Research Committee, Medical College of Wisconsin |
2009 Chair, Ad-Hoc Study Section, Polycystic Kidney Disease, NIH |
2009 - Present Member, Cardiovascular Center Scientific Advisory Committee, Medical College of Wisconsin |
2012 Member, International Organizing Committee, 3rd International Conference on Pediatric Chronic Diseases, Disability and Human Development, Jerusalem, Israel |
2013 Scientific Advisor and Reviewer, Goldman Family Trust for PKD Research |
2013 Consultant, Human ADPKD Clinical Trials, Kadmon Pharmaceticals (SRA executed through MCW Grants and Contracts) |
2013 Member, Internal Advisory Committee, Children’s Environmental Health Center, NIEHS-ES004184-26 (P.I.: David Petering, University of Wisconsin, Milwaukee) |
2013 Consultant, Clinical Trials ARPKD, NIH- NHGRI (National Human Genome Research Institute) |
2013 Member, Infrastructure Task Force, American Society of Pediatric Nephrology |
2014 Invited Moderator, “Extra-renal manifestations, confounding factors, and biomarkers in PKD” FASEB PKD Meeting,Italy |
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
International |
State of the Art: Experimental Cystic Kidney Disease, Seventh International Congress of Pediatric Nephrology, Tokyo, Japan, 09/1986 - Present |
Development of Renal Epithelium in Organotypic Culture, Third International Workshop on Developmental Renal Physiology, Tokyo, Japan, 09/1986 - Present |
Recent Advances in Developmental Nephrology: Growth Factor Control of Nephrogenesis, Seventh International Congress of Pediatric Nephrology, Tokyo, Japan, 09/1986 - Present |
Organ Culture Models in the Study of Cystic Kidney Disease, Second International Workshop on Polycystic Kidney Disease, Oxford, England, 07/1987 - Present |
Renal Growth and Development: In Vitro Studies of Renal Organogenesis, American Physiological Society Annual Meeting, Montreal, Canada, 10/1988 - Present |
Experimental Approaches to Renal Cystic Disease, Eighth International Congress of Pediatric Nephrology, Toronto, Canada, 08/1989 - Present |
Growth Factors in Normal and Abnormal Renal Differentiation, International Workshop on Developmental Renal Physiology, Montreal, Canada, 08/1989 - Present |
New Developments in Pediatric Nephrology, American Academy of Pediatrics CME Course, Calgary, Alberta, CAN, 07/1991 - Present |
Altered Epithelial Polarity and Growth Factor Responses in Metanephric Maldevelopment, Fifth International Workshop on Developmental Renal Physiology, Tremezzo, Italy, 08/1992 - Present |
Cellular Pathophysiology of Polycystic Kidney Disease, Twelfth International Congress of Nephrology, Jerusalem, Israel, 06/1993 - Present |
The Biological Basis of Renal Dysplasia and Renal Cystic Disease, Annual Kidney Research Aid Fund Lecture, Institute of Child Health, London, England, 03/1994 - Present |
Progress in Pediatric Renal Disease, Child Health 200 - 2nd World Congress and Exposition, Pediatric Postgraduate Course, Vancouver, British Columbia, Canada, 06/1995 - Present |
Pathophysiology of Renal Cyst Formation: Implications for the Clinician, 10th Congress of the International Pediatric Nephrology Association, Santiago, Chile, 08/1995 - Present |
Cellular Pathophysiology of Cystic Kidney Disease: Insights into Future Therapies, 7th International Workshop on Developmental Nephrology, Stockholm, Sweden, 09/1998 - Present |
Cellular Pathophysiology of Polycystic Kidney Disease, 11th Congress of the International Pediatric Nephrology Association, London, England, 09/1998 - Present |
Polycystic Kidney Disease: Insights into Future Therapies, Princess Lilian Cardiology Foundation International Symposium, Brussels, Belgium, 10/1998 - Present |
Polycystic Kidney Disease, Brandeis Symposium - 30 Years of Pediatric Nephrology: Past, Present and Future, Freiberg, Germany, 06/1999 - Present |
Developmental Biology of Polycystic Kidney Disease, Annual Meeting of the Japanese Society of Nephrology, Tokyo, Japan, 06/1999 - Present |
Annual Meeting of the Japanese Society of Nephrology, Cellular Pathophysiology of Polycystic Kidney Disease, Tokyo, Japan, 06/1999 - Present |
Polycystic Kidney Disease, Departments of Pediatrics and Medicine, Kobe University, Kobe, Japan, 06/1999 - Present |
Factors Modulating Cyst Growth: New Therapeutic Targets in PKD, American Society of Pediatric Nephrology Annual Meeting, Toronto, Ontario, Canada, 10/2000 - Present |
Department of Pediatrics, Khon Kaen University, Khon Kaen, Thailand, 02/2001 - Present |
Renal Emergencies, Management of Complex Humanitarian Emergencies: Focus on Children and Families, Khon Kaen University, Khon Kaen, Thailand, 02/2001 - Present |
Department of Pediatrics, National University of Laos, Faculty of Medical Sciences, Vientiane, Laos, 02/2001 - Present |
From Laboratory Investigation to Patient Bedside: Polycystic Kidney Disease in the 21st Century, Jean Pouliot Lectureship, Montreal Children’s Hospital Research Institute and Hospital Sainte-Justine, Montreal, Canada, 03/2001 - Present |
Research Update: Cellular Pathophysiology of Polycystic Kidney Disease, Montreal Children’s Hospital Research Institute, Montreal, Montreal, Canada, 03/2001 - Present |
Departments of Medicine and Pediatrics, Wakayama Medical School, Wakayama, Japan, 11/2002 - Present |
Molecular and Cellular Pathophysiology of PKD, Plenary Speaker, Kinki Pediatric Nephrology Meeting, Osaka, Japan, 11/2002 - Present |
Renal Cystic Disease in the 21st Century: New Insights for the Clinician, 15th Israel Medical Week, Children’s Day in Medicine, Tel Aviv, Israel, 03/2004 - Present |
New Insights into the Treatment of Polycystic Kidney Disease, Plenary Speaker, 13th Congress of the International Pediatric Nephrology Association, Adelaide, Australia, 09/2004 - Present |
Functional Genomics: New Therapies for PKD in the 21st Century, 9th Asian Congress of Pediatric Nephrology, Beijing, China, 10/2005 - Present |
Clinical Evaluation of the Abnormal Urinalysis, National University of Nigeria, Pediatric Grand Rounds, Abuja, Nigeria, 10/2006 - Present |
Plenary Symposium: New Approaches to UTI-VUR, 25th International Congress of Pediatrics, Athens, Greece, 2007 |
IPNA Symposium: Update on Common Childhood Kidney Problems, 25th International Congress of Pediatrics, Athens, Greece, 2007 |
Hematuria and Glomerulonephritis: A Guide for the Perplexed Physician, Editor’s Choice Conference, Krakow, Poland, 06/2008 - Present |
Renal Cystic Disease: New Insights for the Clinician, Editor’s Choice Conference, Krakow, Poland, 06/2008 - Present |
New Therapies for PKD, Annual Meeting of the European Society of Pediatric Nephrology, Lyon, France, 09/2008 - Present |
Translational Research in PKD: New Therapies on the Horizon, 2nd Gerry Schwartz and Heather Reisman International Congress on Children with Chronic Diseases, Jerusalem, Israel, 12/2008 - Present |
“Developing therapies for chronic genetic diseases: PKD as a model” (Plenary Session) and “Challenges of Mentoring in the Current Pediatric Academic Environment”(Educational Symposium), International Congress on Childhood Chronic Diseases, Jerusalem, Israe, 12/2012 |
“Translational Therapies for Childhood Polycystic Kidney Disease”, Pediatric Academic Societies Invited Plenary Lecture; Symposium on “Hot Topics in Pediatric Research”, Vancouver, B.C., 05/2014 |
National |
Organ Culture in Renal Research, Conference on Cell/Tissue Culture in Renal Research, Bethesda, MD, 09/1985 - Present |
New Aspects of Polycystic Kidney Disease: Pathogenesis of Renal Cyst Formation, American Society of Nephrology Annual Meeting, Washington, DC, 12/1986 - Present |
In Vitro Approaches to the Study of Mammalian Nephrogenesis, New York Nephrology Society Invited Lecturer Series, New York, NY, 01/1988 - Present |
Transtubular Solute Transport in Experimental Cystic Nephrogenesis, Polycystic Kidney Research Foundation-Baxter Health Care Roundtable on New Insights into Polycystic Kidney Disease, Kansas City, KS, 09/1988 - Present |
Nephrology Update for the Pediatric Practitioner, American Academy of Pediatrics Annual Meeting, Seattle, WA, 05/1990 - Present |
The Value of In Vitro Methods in Renal Research, American Society of Pediatric Nephrology Annual Meeting, Anaheim, CA, 05/1990 - Present |
The Formation and Expansion of Renal Cysts, Renal Cystic Disorders, Annual Scientific Meeting of the National Kidney Foundation, Washington, DC, 11/1990 - Present |
New Approaches to Common Urinary Tract Problems in Children, Children’s Hospital and Medical Center CME Course, Seattle, WA, 09/1991 - Present |
Pediatric Nephrology Update, American Academy of Pediatrics CME Course, San Francisco, CA, 02/1992 - Present |
Murine Models of Recessive PKD, NIH Conference on Molecular Genetics of Kidney Disease, Reston, VA, 03/1992 - Present |
Growth Factor Alterations in Cystic Kidney Disease, Fifth International Workshop on PKD,, Kansas City, MO, 06/1992 - Present |
State of the Art: Molecular and Cell Biology of Polycystic Kidney Disease, Ninth Congress of the International Pediatric Nephrology Association, Jerusalem, Israel, 09/1992 - Present |
Epithelial Cell Pathophysiology in Polycystic Kidney Disease, Keystone Symposia on Epithelial and Neuronal Cell Polarity and Differentiation, Tamarron, CO, 02/1993 - Present |
The Responsibilities of Mentorship, University of Washington Biomedical Research Integrity Lecture Series, Seattle, WA, 07/1993 - Present |
Polycystic Kidney Disease" and "Hemolytic-Uremic Syndrome, 13th Annual Advanced Nephrology for the Consultant Postgraduate Course, San Diego, CA, 01/1994 - Present |
Pathogenesis and Manifestations of Cystic Renal Disorders, Pediatric Nephrology Seminar XXI, University of Miami Postgraduate Course, Miami, FL, 02/1994 - Present |
ESRD Therapy in the Infant and Young Child, Pediatric Nephrology Seminar XXI, University of Miami Postgraduate Course, Miami, FL, 02/1994 - Present |
The Case Against Preemptive Transplantation, North American Pediatric Renal Transplant Cooperative Study Annual Meeting, Newport Beach, CA, 04/1994 - Present |
The Cellular Basis of Renal Cyst Formation and Enlargement, Forefronts in Nephrology Symposium, International Society of Nephrology, Niagara, NY, 05/1994 - Present |
Common Urinary Tract Problems in Children, Children’s Hospital and Medical Center CME Course, Seattle, WA, 09/1994 - Present |
Epithelial-Mesenchymal Morphogenesis, American Society of Nephrology Annual Meeting, Orlando, FL, 10/1994 - Present |
Cellular Pathophysiology of Polycystic Kidney, NKF Symposium on Genetic and Developmental Aspects of Renal Disease, National Kidney Foundation Annual Meeting, Orlando, FL, 10/1994 - Present |
Molecular and Cellular Pathophysiology of Polycystic Kidney Disease, Spokane Society of Internal Medicine/National Kidney Foundation of Washington Annual Meeting, Spokane, WA, 02/1995 - Present |
Molecular Genetics of Polycystic Kidney Disease, Pediatric Nephrology Seminar XXII, University of Miami Postgraduate Course, Miami, FL, 02/1995 - Present |
Why Does Chronic Renal Disease in Children Progress?, Pediatric Nephrology Seminar XXII, University of Miami Postgraduate Course, Miami, FL, 02/1995 - Present |
Clinical Implications of the Molecular and Cellular Biology of Polycystic Kidney Disease, 11th Annual Mitchell Rubin Lectureship in Pediatric Nephrology, 03/1995 - Present |
Molecular and Cellular Biology of Normal and Abnormal Nephrogenesis, AMSPDC Frontiers in Science, San Diego, CA, 03/1995 - Present |
The Cell Biology of Renal Tubular Maldevelopment, 6th International Workshop on Developmental Nephrology, Airlie, VA, 08/1995 - Present |
Polycystic Kidney Disease in the Pediatric Patient, National Kidney Foundation Symposium on Polycystic Kidney Disease, National Kidney Foundation Annual Meeting, San Diego, CA, 11/1995 - Present |
Progressive Nephropathy: Mechanisms and Possible Therapies, Pediatric Nephrology Seminar XXIII, University of Miami Postgraduate Course, Miami, FL, 02/1996 - Present |
Pathogenesis of Renal Cystic Disease, Sixth Annual Workshop of the North American Pediatric Renal Transplant Cooperative Study, Washington, DC, 03/1996 - Present |
From Bench to Bedside: Polycystic Kidney Disease, David Cornfeld, M.D. Annual Lecture, Children’s Hospital of Philadelphia, PA, 04/1996 - Present |
From Bench to Bedside: Clinical Implications of Current Investigation in Polycystic Kidney Disease, Pediatric Grand Rounds, Johns Hopkins Hospital, Baltimore, MD, 10/1996 - Present |
Responsibilities of Mentoring, Association of American Medical Colleges Third Annual GREAT Conference,, Scottsdale, AZ, 10/1996 - Present |
Symposium on Disease Progression in Pediatric Chronic Renal Insufficiency, American Society of Pediatric Nephrology Annual Meeting, 1996 |
What is the Role of Molecular Genetics in Diagnosis of Renal Disease?”, Pediatric Nephrology Seminar XXIV, University of Miami Postgraduate Course, Miami, FL, 02/1997 - Present |
Ethical Implications of Genetic Diagnosis of Non-Lethal Renal Diseases, Pediatric Nephrology Seminar XXIV, University of Miami Postgraduate Course, Miami, FL, 02/1997 - Present |
The Contribution of GU Anomalies to ESRD: Is There Hope for Therapy?, Pediatric Nephrology Seminar XXIV, University of Miami Postgraduate Course, Miami, FL, 02/1997 - Present |
Molecular Genetics of Polycystic Kidney Disease, American Society of Pediatric Nephrology Annual Meeting, Washington, DC, 05/1997 - Present |
Three Rivers Clinical Pediatric Update, University of Pittsburgh School of Medicine, Pittsburgh, PA, 06/1997 - Present |
Pediatric Hypertension, 45th Annual Medical Alumni Day, Children’s Hospital of Pittsburgh, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, 06/1997 - Present |
Childhood Polycystic Kidney Disease, Kidney Foundation of Ohio 22nd Annual Renal Symposium, Cuyahoga Falls, OH, 09/1997 - Present |
American Medical School Pediatric Department, Task Force on Housestaff Recruitment, 1997 |
Basic Concepts, Pediatric Nephrology Seminar XXV, University of Miami Postgraduate Course, Miami, FL, 02/1998 - Present |
Autosomal Polycystic Kidney Disease: New Approaches, Pediatric Nephrology Seminar XXV, University of Miami Postgraduate Course, Miami, FL, 02/1998 - Present |
Research Advances in Cystic Kidney Diseases, Keynote Address, Polycystic Kidney Research Foundation Annual Meeting, Washington, D.C, 06/1998 - Present |
Cellular Pathophysiology of ARPKD: Insights into Future Therapies, Renal Research Seminar, The Mt. Sinai Medical Center, New York, NY, 11/1998 - Present |
From Bench to Bedside: The Cellular Pathophysiology of Polycystic Kidney Disease, Pediatric Grand Rounds, Mt. Sinai Medical Center, New York, NY, 11/1998 - Present |
New Advances in Childhood Polycystic Kidney Disease, Pediatric Grand Rounds, University of Tennessee, Knoxville, TN, 03/1999 - Present |
New Insights into the Pathophysiology and Treatment of Polycystic Kidney Disease, New York Society of Nephrology, New York, NY, 03/1999 - Present |
State of the Art: Polycystic Kidney Disease, 3rd Northern California Pediatric Nephrology Symposium, San Francisco, CA, 10/1999 - Present |
State of the Art: Polycystic Kidney Disease, 3rd Northern California Pediatric Nephrology Symposium, San Francisco, CA, 10/1999 - Present |
Department of Pediatrics, Stanford University, San Francisco, CA, 10/1999 - Present |
Promising Novel Therapeutic Strategies for PKD, Clinical Science Symposium, American Society of Nephrology Annual Meeting, Miami, FL, 11/1999 - Present |
New Insights into the Diagnosis and Management of Childhood UTIs, Phoenix Children’s Hospital Winter Pediatric Update 2000, Phoenix, AZ, 02/2000 - 03/2000 |
Hematuria: A Guide for the Perplexed, Phoenix Children’s Hospital Winter Pediatric Update 2000, Phoenix, AZ, 02/2000 - 03/2000 |
Therapeutic Implications of EGFR Abnormalities in Polycystic Kidney Disease, Genetics Institute Medical Advisory Board Meeting, Boston, MA, 09/2000 - Present |
Proteinuria and the Nephrotic Syndrome, Children’s Hospital Winter Pediatric Update 2000, Phoenix, AZ, 2000 |
Department of Pediatrics, Phoenix Children’s Hospital, University of Arizona School of Medicine, 04/2001 - Present |
Office Management of Hematuria: Guide for the Perplexed, Office Management of Hematuria: Guide for the Perplexed, Cleveland, OH, 04/2001 - Present |
March of Dimes Visiting Professor, Department of Pediatrics, Albert Einstein College of Medicine, New York, NY, 02/2002 - Present |
From Bench to Bedside: New Therapies for Polycystic Kidney Disease, New York Academy of Medicine, New York, NY, 02/2002 - Present |
Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 03/2003 - Present |
Departments of Pediatrics and Medicine, State University of New York – Downstate, Brooklyn, NY, 06/2003 - Present |
Factors Modulating Cyst Growth: New Therapies for Polycystic Kidney Disease, Arkansas Children’s Hospital Research Institute, Little Rock, AR, 07/2003 - Present |
Plenary Symposium, Pediatric Solid Organ Transplantation in the 21st Century, Pediatric Academic Societies Annual Meeting, Seattle, WA, 2003 |
Scientific Program Committee, American Society of Nephrology, 2004 Annual Meeting, 2003 - 2004 |
Hematuria and Acute Glomerulonephritis, 24th International Congress of Pediatrics, Cancun, Mexico, 08/2004 - Present |
Urinary Tract Infections and Renal Scarring, 24th International Congress of Pediatrics, Cancun, Mexico, 08/2004 - Present |
Molecular and Cellular Pathophysiology of Polycystic Kidney Disease, University of Washington, Department of Pediatrics, Seattle, WA, 11/2004 - Present |
Plenary Symposium, Common Urinary Tract Problems in Children, 24th Congress of the International Pediatric Association, 2004 |
Basic Science Symposium, Non-mammalian Models of Renal Development/Disease, American Society of Nephrology Annual Meeting, 2004 |
Targeting the EGF Receptor in ARPKD- Special Research Conference on Innovative Therapies in ARPKD, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 05/2005 - Present |
New Therapeutic Targets for Polycystic Kidney Disease (PKD), ImClone Systems Incorporated, New York, NY, 07/2005 - Present |
EGFR Inhibitors: Effects on PKD Phenotypes, FASEB Summer Research Conference. New Insights in PKD: Molecular Pathways, Pathogenic Mechanisms and Translational Applications, Saxtons River, VT, 08/2005 - Present |
Hematuria: A Guide for the Perplexed Physician, Penn State University College of Medicine, Milton S. Hershey Medical Center, Pediatric Residents Noon Conference, Hershey, PA, 03/2006 - Present |
Renal Cystic Disease in the 21st Century: Insights for the Clinician, Penn State University College of Medicine, Milton S. Hershey Medical Center - Combined Medicine and Pediatric Grand Rounds, Hershey, PA, 03/2006 - Present |
New Approaches to Therapy in PKD, Albert Einstein College of Medicine, Pediatric Grand Rounds, Bronx, NY, 02/2007 - Present |
Targeting Signaling Intermediates in PKD: Therapeutic Efficacy of Src-Inhibition, Polycystic Kidney Disease, FASEB Summer Research Conference, Snowmass, CO, 07/2008 - Present |
PKD: New Insights into Future Therapy”, Academic Pediatric Nephrology Symposium: Bench, Bedside and Beyond (Bernard Sidney Kaplan Festschrift), Children’s Hospital of Philadelphia, Phildelphia, PA, 05/2009 - Present |
ARPKD: Current and Future Management of Progressive Renal Disease, Symposium on Autosomal Recessive Renal Disease, 15th International Congress of the International Pediatric Nephrology Association, New York, NY, 08/2010 - Present |
“Future Therapies for PKD: The Impact of Translational Research.”, First Annual Dr.Demetrius Ellis Lectureship, Children’s Hospital of Pittsburgh, Pittsburgh, 02/2014 |
Professional Advisory Board, ARPKD/CHF Alliance |
Regional |
Polycystic Kidney Disease in Renal Explants, Polycystic Kidney Research Foundation-Baxter Health Care Workshop on the Etiology and Pathogenesis of PKD, Lake Forest, IL, 09/1987 - Present |
New Insights into Renal Cystic Disease, Plenary Session on Perinatal Pediatrics and Nephrology, American Academy of Pediatrics Annual Meeting, Chicago, IL, 10/1989 - Present |
Update in Pediatric Nephrology, American Academy of Pediatrics Annual Spring Meeting, Chicago, IL, 03/1993 - Present |
Challenges in the Diagnosis and Management of the Child with Hypertension, Pediatrics Today Conference, Rainbow Babies and Children’s Hospital, Cleveland, OH, 02/1996 - Present |
Pediatric Nephrology: What is the Role of the Routine Urinalysis in Health Care Maintenance?, American Academy of Pediatrics Annual Meeting, Chicago, IL, 04/1996 - Present |
Abnormal Epidermal Growth Factor Receptor Expression in Autosomal Recessive Polycystic Kidney Disease (ARPKD), Page-Wood International Symposium on Membrane Traffic in Health and Disease, Cleveland, OH, 09/1996 - Present |
Mentoring in a Turbulent Health Care Environment, Dean’s Distinguished Lecture, Wayne State University School of Medicine, Detroit, MI, 10/1997 - Present |
Parke-Davis Research, Pathophysiology of Polycystic Kidney Disease: Implications for the Development of Future Therapies, Ann Arbor, MI, 01/2000 - Present |
Pathophysiology of Polycystic Kidney Disease: Implications for the Development of Future Therapies, Parke-Davis Research, Ann Arbor, MI, 01/2000 - Present |
Departments of Pediatrics and Medicine, The University of Iowa College of Medicine, Iowa City, IA, 04/2000 - Present |
ARPKD: An Integrated Perspective, Polycystic Kidney Research Foundation Annual Meeting, Chicago, IL, 06/2000 - Present |
ARPKD: What the Future Holds, Polycystic Kidney Research Foundation Annual Meeting, Chicago, IL, 06/2000 - Present |
Renal Crush Syndrome, Complex Humanitarian Emergencies Course, Case Western Reserve University, Cleveland, OH, 07/2001 - Present |
Departments of Medicine and Pediatrics, Ohio State University, Columbus, OH, 10/2001 - Present |
Renal Complications of Complex Humanitarian Emergencies, Complex Humanitarian Emergencies Course, Case Western Reserve University, Cleveland, OH, 06/2002 - Present |
Targeting the EGFR Axis in PKD, FASEB Conference on Molecular Mechanisms and Therapeutic Insights into PKD, Tucson, AZ, 08/2002 - Present |
Renal Complications of Complex Humanitarian Emergencies, Complex Humanitarian Emergencies Course, Case Western Reserve University, Cleveland, OH, 06/2003 - Present |
Polycystic Kidney Disease: From Molecular Pathophysiology to New Therapies, University of Miami Pediatric Nephrology Symposium, Miami, FL, 02/2005 - Present |
Local |
Chair, 1996 Basic Science Conference:, American Society of Nephrology, 1996 |
Free Communications Session on Recent Advances in Polycystic Kidney Disease, American Society of Pediatric Nephrology Annual Meeting, 1997 |
From Bench to Bedside: New Therapeutic Approaches to Childhood Polycystic Kidney Disease, Medical College of Wisconsin, Milwaukee, WI, 01/2004 - Present |
Hematuria and Glomerulonephritis, Editor’s Choice Conference, Children’s Hospital of Wisconsin, Milwaukee, WI, 06/2005 - Present |
New Therapeutic Targets for Polycystic Kidney (PKD), Department of Physiology Weekly Seminar, Medical College of Wisconsin, Milwaukee, WI, 05/2008 - Present |
Translational Research in PKD: New Therapies on the Horizon, Children’s Research Institute Noon Academic Conference, Children’s Hospital Health System, Milwaukee, WI, 07/2008 - Present |
Childhood Polycystic Kidney Disease in the 21st Century, Department of Pediatrics Grand Rounds, University of Wisconsin, Madison, WI, 01/2009 - Present |
Evolving Concepts in the Evaluation and Treatment of Childhood Polycystic Kidney Disease, Pediatric Grand Rounds, Children’s Hospital of Wisconsin, Milwaukee, WI, 01/2009 - Present |
ADPKD Therapeutics on the Horizon: Hope or Hype?, Division of Internal Medicine Nephrology Grand Rounds, Medical College of Wisconsin, Milwaukee, WI, 08/2009 - Present |
Renal Bedside Physiology = Clinical Nephrology, 2010 Medical Physiology Course, Medical College of Wisconsin, Milwaukee, WI, 03/2010 - Present |
“Clinical Correlations: Renal Physiology”, 2011 Medical Student Physiology Course, Medical College of Wisconsin, Milwaukee, WI, 02/2011 |
“Clinical Correlations:: Renal Physiology.", 2012 Medical Student Physiology Course, Medical College of Wisconsin, Milwaukee, WI, 02/2012 |
“Mentoring: A Guide for the Perplexed Mentor and Trainee.”, Children’s Research Institute, Milwaukee, WI, 01/2013 |
“Opportunities for Research in Pediatric Nephrology and Polycystic Kidney Disease.”, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, 01/2013 |
“Translational Biology of PKD: Insights into Future Therapies”, Department of Medicine, Nephrology Research Conference, Medical College of Wisconsin, Milwaukee, WI, 01/2013 |
“New Approaches to Translational Research in PKD.”, MSTP Training Program, Medical College of Wisconsin, Milwaukee, WI, 06/2013 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
1986 - 1988 Member, Career Counseling Committee, University of Pittsburgh School of Medicine |
1991 - 1993 Member, Committee on Issues in Biomedical Research Integrity, University of Washington |
1991 - 1995 Faculty Senator, University of Washington |
1991 - 1995 Member, Faculty Council on Scientific Affairs, University of Washington |
1995 - 2004 Member, Executive Committee, Case Western Reserve University School of Medicine |
1996 - 2002 Member, Strategic Planning Committee, Office of the Dean, Case Western Reserve University School of Medicine |
1996 - 2004 Member, Honorary Degree Committee, Case Western Reserve University |
1997 - 1998 Chair, Chair Search Committee, Department of Medicine, Case Western Reserve University School of Medicine |
1998 - 2004 Member, Tenure Compensation Committee, Case Western Reserve School of Medicine |
1998 - 2001 Member, Chair Search Committee, Department of Reproductive Biology, Case Western Reserve University School of Medicine |
1999 - 2000 Chair, Chair Search Committee, Department of Psychiatry, Case Western Reserve University School of Medicine |
1999 - 2004 Member, Program Advisory Committee, Howard Hughes Medical Institute Biomedical Research Support Program, Case Western Reserve University School of Medicine |
1999 - 2001 Member, Chair Search Committee, Department of Family Medicine, Case Western Reserve University School of Medicine |
1999 - 2001 Member, Faculty Council, Case Western Reserve University School of Medicine |
2000 - 2004 Member, Clinical Research Scholars Program Advisory Committee, Case Western Reserve University School of Medicine |
2002 - 2003 Member, Chair Search Committee, Department of Orthopedics, Case Western Reserve University School of Medicine |
2010 - 2015 Member, Scientific Program Advisory Committee, Master of Science in Clinical & Translational Health, Medical College of Wisconsin |
2010 - 2015 Member, Scientific Program Advisory Committee, Master of Science in Clinical & Translational Health, Medical College of Wisconsin |
2011 Internal Advisor, Children’s Environmental Health Sciences Core Center |
2011 - Present Member, CTSI Citizens Advisory Council, CTSI Community Engagement Key Function |
2011 Chair, Research Committee, Department of Pediatrics, Medical College of Wisconsin |
2011 - 2013 Member, Transitional Leadership Group, Department of Pediatrics, Medical College of Wisconsin |
2011 - Present Member, Research Advisory Board, Cancer Cell Biology Research Program, Medical College of Wisconsin |
2011 - Present Board Member, Internal Advisory Board, Cancer Center, Medical College of Wisconsin |
2012 Member, Finance Committee, Department of Pediatrics, Medical College of Wisconsin |
2012 - Present Member, Internal Advisory Board, Medical College of Wisconsin Cancer Center |
Hospital |
1982 - 1988 Member, Utilization Review Committee, Children's Hospital of Pittsburgh |
1983 - 1988 Member, Animal Research and Care Committee, Children's Hospital of Pittsburgh |
1983 - 1988 Member, Resident Selection Committee, Children's Hospital of Pittsburgh |
1991 - 1994 Chair, Animal Care and Use Committee, Children's Hospital and Medical Center, Seattle |
1993 - 1995 Member, Quality Improvement/Peer Review Committee, Children's Hospital and Medical Center, Seattle |
1993 - 1995 Member, Managed Care Committee, Department of Medicine, Children's Hospital and Medical Center, Seattle |
1993 - 1995 Chair, Fellowship Funding Committee, Children's Hospital and Medical Center, Seattle |
1993 - 1995 Member, Contracts Committee, Children's University Medical Group, Seattle |
1994 - 1995 Member, Regional Outreach Task Force, Children’s Hospital and Medical Center, Seattle |
1994 - 2004 Co-Chair, Facilities Design Team, Children’s Hospital and Medical Center, Seattle |
1995 - 2004 Member, Executive Committee, Clinical Council, University Hospitals of Cleveland |
1995 - 2004 Member, Clinical Council, University Hospitals of Cleveland |
1995 - 2004 Chair, Children’s Research Foundation, Cleveland |
1995 - 2004 Member, Clinical Leadership Advisory Committee, University Hospitals of Cleveland |
1995 - 2004 Member, University Primary Care Physicians / University Faculty Practice Association Liaison Committee, University Hospitals of Cleveland |
1995 - 2004 Member, Council of Clinical Chairs, University Hospitals of Cleveland |
1995 - 1998 Member, Board of Directors, University Faculty Practice Association, University Hospitals of Cleveland |
1996 - 1998 Member, Executive Committee, University Faculty Practice Association |
1996 - 2003 Member, Clinical Council Credentialing Subcommittee, University Hospitals of Cleveland |
1997 - 2004 Member, Minority Faculty Development Committee, University Hospitals of Cleveland |
1998 - 2003 Member, Internal Affiliation Committee, University Hospitals of Cleveland |
1999 - 2003 Member, Executive Board, University Hospitals Faculty Services |
1999 - 2003 Member, Policy Advisory Committee, Research Institute, University Hospitals of Cleveland |
1999 - 2003 Member, Operational Advisory Committee, University Hospital Faculty Services |
1999 - 2003 Member, Space Planning Committee, Research Institute, University Hospitals of Cleveland |
1999 - 2004 Member, Ad Hoc Committee, Safety of Polyvinylchloride/Phthalates, University Hospitals of Cleveland |
1999 - 2004 Member, Mary B. Lee Endowment Fund Committee, University Hospitals of Cleveland |
2000 - 2003 Member, Executive Committee, University Hospitals Research Institute, Cleveland |
2000 - 2003 Member, Quality Monitoring Council, University Hospitals of Cleveland |
2000 - 2003 Member, Performance Indicators Advisory Committee, University Hospitals of Cleveland |
2000 - 2004 Chair, Educational and Research Mission Workgroup, University Hospitals of Cleveland |
2000 - 2003 Member, Conflict of Interest Policy Development Committee, University Hospitals Research Institute, Cleveland |
2000 - 2004 Member, CWRU/UHC Research and Intellectual Property Task Force, University Hospitals of Cleveland |
2001 - 2004 Member, Medical Resource Management Steering Committee, University Hospitals of Cleveland |
2002 - 2003 Member, Blueprint for Change Committee (Rainbow Babies & Children’s Hospital Service Line), University Hospitals of Cleveland |
2002 - 2003 Member, Affiliation Committee, University Hospitals and Case Western Reserve University, Cleveland |
2003 - 2004 Chair, Executive Steering Committee, Children’s Research Foundation / ECG Management Consultants Project |
2005 - 2012 Member, Strategic Planning Committee, Children’s Hospital and Health System Foundation, Milwaukee |
2007 - 2012 Chair, Children’s Research Campaign Sub-Committee, Children’s Hospital and Health System Foundation, Milwaukee |
2013 - Present Ex Officio Research Advisor, Children’s Research Institute |
MCW TEACHING ACTIVITIES: |
Medical Student Education |
2013 Senior Mentor, K-12 Club, Department of Pediatrics |
2013 Advisor, T-32 Training Grant Program, Department of Pediatrics |
2013 Facilitator, “Professionalism”; 3rd year MCW Medical Students |
EXTRAMURAL TEACHING: |
Medical Student Education |
1992 - 1995 University of Washington, 1992-1995 Regular Lecturer, Pediatrics 512P: Seminars in Human Embryology and Teratology |
1992 - 1995 University of Washington, Regular Lecturer, Pediatrics 512P: Seminars in Human Embryology and Teratology |
Graduate Student Education |
1987 Albert Einstein College of Medicine, Bronx, New York, Department of Pediatrics |
10/1991 Washington University, St. Louis, Missouri, Department of Medicine |
1993 University of Toronto and Hospital for Sick Children, Toronto, Canada, Departments of Medicine and Pediatrics |
Continuing Medical Education |
02/1992 Stanford University, Palo Alto, California, Department of Molecular and Cellular Physiology |
02/1993 Stanford University, Palo Alto, CA, Department of Molecular and Cellular Physiology |
06/1994 Mayo Clinic, Rochester, Minnesota, Department of Medicine |
12/1994 University of Alabama at Birmingham, Department of Medicine |
03/1995 State University of New York - Buffalo, NY, Department of Pediatrics |
12/1995 Indiana University School of Medicine, Indianapolis, IN, Departments of Medicine and Anatomy and Cell Biology |
01/1996 Harvard University and the Children’s Hospital, Boston, MA, Departments of Pediatrics and Anesthesia |
04/1996 University of Pennsylvania School of Medicine, Philadelphia, PA, Department of Pediatrics |
10/1996 Johns Hopkins University School of Medicine, Baltimore, Maryland, Department of Pediatrics |
10/1997 Wayne State University School of Medicine, Children’s Hospital of Michigan, Detroit, Michigan, Department of Pediatrics |
11/1998 Mt. Sinai School of Medicine, New York, NY, Departments of Pediatrics and Medicine |
02/1999 National University of Laos, Faculty of Medical Sciences, Vientiane, Laos, Department of Pediatrics |
02/1999 Khon Kaen University, Khon Kaen, Thailand, Department of Pediatrics |
10/1999 University of California San Francisco, San Francisco, CA, Department of Pediatrics |
06/2003 Emory University School of Medicine, Atlanta, GA, Department of Pediatrics |
11/2004 University of Washington School of Medicine, Seattle, WA, Department of Pediatrics |
03/2006 Penn State University, Milton S. Hershey Medical Center, Hershey, PA, Department of Pediatrics |
02/2007 Albert Einstein College of Medicine, Children’s Hospital at Montefiore, New York, NY, Departments of Pediatrics and Medicine |
12/2008 Technion University and Rambam Medical Center, Haifa, Israel, Departments of Pediatrics and Physiology |
01/2009 University of Wisconsin, School of Medicine and Public Health, Madison, WI, Department of Pediatrics |
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Undergraduate Students |
2011 - Present Katherine Eisenbrown, Medical College of Wisconsin |
Postdoctoral Students |
2010 - Present Megan Determan, Medical College of Wisconsin |
2013 - Present Ameya Patil, M.D., Research, Medical College of Wisconsin, Current Position: Assistant Professor of Pediatrics |
EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Medical Students |
1997 - 1999 Ali Harari, M.D. |
1998 - 2001 Crystal Murcia |
Postdoctoral Students |
1989 - 1991 Yuko Ozawa, M.D., Ph.D., Nagoya University |
1990 - 1993 Ruth McDonald, M.D. |
1990 - 1993 Consuelo Glen, M.D. |
1990 - 1993 Jeroen Nauta, M.D., Ph.D. |
1990 - 1993 Consuelo Glen, M.D. |
1991 - 1994 Gregory Sliman, M.D. |
1991 - 1994 Judith Pugh, M.D. |
1992 - 1995 John Brandt, M.D., Professor of Pediatrics; Director, Pediatric Nephrology; University of New Mexico, Albuquerque, NM |
1993 - 1996 Robert Holleman, M.D, Professor of Clinical Pediatrics; Director, Pediatric Residency Program and Chief of Pediatric Nephrology; University of South Carolina School of Medicine ,Columbia, SC |
1993 - 1996 Nicole Becker, M.D. |
1994 - 1997 Mark Joseph, M.D., Associate Professor of Pediatrics (Nephrology); Phoenix Children’s Hospital, Phoenix, AZ |
1994 - 1998 Annamaria T. Kausz, M.D., M.S., Associate Professor of Pediatrics and Medicine (Nephrology); Tufts University School of Medicine, Boston, MA |
1998 - 2000 Koichi Nakanishi, M.D., Ph.D., Associate Professor and Chief, Pediatric Nephrology; Wakayama University Medical Center, Wakayama, Japan |
1998 - 2000 Noel Murcia, Ph.D., Clinical Assistant Professor, Department of Pediatrics; Case Western Reserve University, Cleveland, OH |
1999 - 2002 Dana Schwartz, Case Western Reserve University |
1999 - 2000 Fatima Tsalicova, M.D., Staff Nephrologist, Institute of Pediatrics and Children’s Surgery; Moscow, Russia |
2000 - 2002 Suwanee Wisanuyotin, M.D., Associate Professor of Pediatric Nephrology; Director, Pediatric Residency Program; Khon Kaen University, Khon Kaen, Thailand |
2000 - 2003 Kiyoshi Hamahira, M.D., Chief, Pediatric Renal Unit; Himeji Red Cross Hospital, Himeji, Japan |
2001 - 2006 Katherine MacRae Dell, M.D., Professor Pediatrics; Director, Division of Pediatric Nephrology; Case Western Reserve University, Cleveland, OH |
2002 - 2003 Aysun Bayazit, M.D., Professor and Director, Department of Pediatric Nephrology; Cukurova University School of Medicine, Adana, Turkey |
2002 - 2004 Rodo O. von Vigier, M.D., Professor of Pediatrics; Director, Pediatric Nephrology; University of Berne, Basil, Switzerland |
2003 - 2004 Ali Duzova, M.D., Associate Professor, Division of Pediatric Nephrology; Hacettepe University, Ankara, Turkey |
2005 - 2006 Nahoko Yata, M.D., Ph.D., Associate Professor, Wakayama University Medical Center, Wakayama, Japan |
2007 - Present Frank Park, Ph.D., Associate Professor, Department of Medicine (Nephrology); Medical College of Wisconsin, Milwaukee, WI |
2007 - Present Eduardo Lau, Ph.D. |
2007 - Present Carol Moreno-Quinn, M.D., Ph.D., Assistant Professor, Department of Physiology (Genetics); Medical College of Wisconsin, Milwaukee, WI |
2007 - 2009 Nadezda Zheleznova, Ph.D., Post Doctoral Fellow, Department of Physiology; Medical College of Wisconsin, Milwaukee, WI |
2007 - Present Priya Pais, MBBS |
2007 - Present Ashraf El-Meanawy, M.D., Ph.D. |
2007 - 2009 Xiaogang Li, Ph.D., Research, Associate Professor, University of Colorado |
2010 - 2013 Kandai Nozu M.D.;PhD, Research, Kobe University, Current Position: Associate Professor of Pediatrics; Director Pediatric Nephrology |
2012 - 2015 Shireen Hashmat, MBBS, Research, University of Chicago School of Medicine, Current Position: Assistant Professor of Pediatrics |
PATENT: |
2006 - Present Allelic Series of Genomic Modification in Cells - Application Serial Number 09/103,846. Filed 12/04; Awarded 2006
Richard P. Woychik, Ph.D., Terry R. Magnuson, Ph.D., and Ellis D. Avner, M.D.
|
08/2009 - Present Methods of Modulating Cell Proliferation and Cyst Formation in Polycystic Kidney and Liver Diseases. Patent # 20080167382 Published August 2009. Ellis D. Avner, Richard Roman, William E. Sweeney. |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Avner ED, Satz J, Plotkin SA: Hypoglycorrhachia in young infants with viral meningitis. J Pediatr 87:833-834, 1975. PMID: 1185362 |
2. Avner ED, Harmon WE, Ingelfinger JR, Levey RH, Grupe WE. Mortality of chronic hemodialysis comparable to that of renal transplantation in pediatric end-stage renal disease. Proc Clin Dial Transplant Forum. 1979;9:1-4. |
3. Avner ED, Harmon WE, Grupe WE, Ingelfinger JR, Eraklis AJ, Levey RH: Mortality of chronic hemodialysis and renal transplantation in pediatric end-stage renal disease. Pediatrics 67:412-416, 1981. PMID: 399499 |
4. Avner ED, Ellis D, Jaffe R, Bowen A: Neonatal radiocontrast nephropathy simulating infantile polycystic kidney disease. J Pediatr 100:85-87, 1982. PMID: 7199081 |
5. Avner ED, Ellis D, Temple T, Jaffe R: Metanephric development in serum-free organ culture. In Vitro Cell Dev Biol 18:675-682, 1982. PMID: 7129481 |
6. Avner ED, Ingelfinger JR, Herrin JT, Link DA, Marcus E, Tolkoff-Rubin NE, Russell-Getz L, Rubin RH: Single-dose amoxicillin therapy of uncomplicated pediatric urinary tract infections. J Pediatr 102:623-627, 1983. PMID: 6339708 |
7. Ellis D, Avner ED, Transue D, Yunis EJ, Drash AL, Becker DJ: Diabetic nephropathy in adolescence: Appearance during improved glycemic control. Pediatrics 71:824-829, 1983. PMID: 6340051 |
8. Avner ED, Sweeney WE, Ellis D: Cyst formation in metanephric organ culture induced by cis-dichlorodiammine platinum (II). Experientia 39:74-76, 1983. PMID: 6681778 |
9. Avner ED, Jaffe R, Temple T, Ellis D, Chung AE: The development of renal basement membrane glycoproteins in metanephric organ culture. Lab Invest 48:263-268, 1983. PMID: 6827806 |
10. Avner ED, Ellis D, Jaffe R: Veno-occlusive disease of the liver associated with cysteamine treatment of nephropathic cystinosis. J Pediatr 102:793-796, 1983. PMID: 6842343 |
11. Avner ED, Sweeney WE, Piesco NP, Ellis D: A new model of glucocorticoid- induced cystic metanephric maldevelopment. Experientia 40:489-490, 1984. PMID: 6723915 |
12. Avner ED, Piesco NP, Sweeney WE, Studnicki FM, Fetterman GH, Ellis D: Hydrocortisone-induced cystic metanephric maldevelopment in serum-free organ culture. Lab Invest 50:208-218, 1984. PMID: 6694360 |
13. Avner ED, Sweeney WE, Finegold DN, Piesco NP, Ellis D: Sodium-potassium adenosine tri-phosphatase activity mediates cyst formation in metanephric organ culture. Kidney Int 28:447-455, 1985. PMID: 2999498 |
14. Avner ED, Sweeney WE, Piesco NP, Ellis D: Growth factor requirements of metanephric differentiation in serum-free murine organ culture. In Vitro Cell Dev Bio 21:297-304, 1985. PMID: 3894316 |
15. Ellis D, Avner ED, Rosenthal JT, Taylor RJ, Young LW, Palumbi MA, Hakala TR: Renal function and somatic growth in pediatric cadaveric renal transplant recipients receiving prednisone-cyclosporine immunosuppression. Am J Dis Child 139:1161-1167, 1985. PMID: 3904407 |
16. Avner ED, Sweeney WE, Piesco NP, Ellis D: Regression of genetically determined polycystic kidney disease in murine organ culture. Experientia 42:77-80, 1986. PMID: 3943602 |
17. Ellis D, Avner ED: Renal failure and dialysis therapy in children with hepatic failure in the perioperative period of orthotopic liver transplantation. Clin Nephrol 25:295-303, 1986. PMID: 3524924 |
18. Ellis D, Avner ED, Kurs-Lasky M, Richards M, Becker DJ: Effects of improved glycemic control on microalbuminemia in adolescents with insulin-dependent diabetes mellitus. Int J Pediatr Nephrol 7:31-39, 1986. PMID: 3957559 |
19. Ellis D, Turocy JW, Sweeney WE, Avner ED: Partial characterization and ontogeny of renal cytosolic glucocorticoid receptors in mouse kidney. J Steroid Biochem 24:997-1003,1986. PMID: 3724151 |
20. Ellis D, Avner ED, Starzl TE: Renal failure in children with hepatic failure undergoing liver transplantation. J Pediatr 108:393-398, 1986. PMID: 3512808. 2010 PMCID PMC2976655. |
21. Ptachinski RJ, Burckart GJ, Rosenthal JT, Venkataramanan R, Howrie DL, Taylor RJ, Avner ED, Hakala TR: Cyclosporine pharmacokinetics in children following cadaveric renal transplantation. Transplant Proc 18:766-768, 1986. |
22. Avner ED, Sweeney WE, Piesco NP, Ellis D: Triiodothyronine-induced cyst formation in metanephric organ culture: The role of increased Na-KATPase activity. J Lab Clin Med l09:441-454, 1987. PMID: 3029256 |
23. Osorio AM, Thun MJ, Novak RF, Van Cura EJ, Avner ED: Silica and glomerulonephritis. Am J Kidney Dis 9:224-231, 1987. PMID: 3030097 |
24. Ellis D, Tran SD, Eagon PK, Avner ED: Reversible inhibition of cytosolic glucocorticoid receptors by mercurial agents. Application in the measurement of total and unoccupied receptors. J Recept Res 7:761-774, 1987. PMID: 3656273 |
25. Avner ED, Studnicki FM, Young MC, Sweeney WE, Piesco NP, Ellis D, Fetterman GH: Congenital murine polycystic kidney disease: I. The ontogeny of tubular cyst formation. Pediatr Nephrol 1:587-596, 1987. PMID: 3153336 |
26. Ellis D. Sothi TD, Avner ED: Glucocorticoids modulate renal glucocorticoid receptors and Na-K ATPase activity. Kidney Int 32:464-471, 1987. PMID: 2828745 |
27. Avner ED: Renal cystic disease: Insights from recent experimental investigations. Nephron 48:89-93, 1988. PMID: 3278246 |
28. Curto KA, Sweeney WE, Avner ED, Piesco NP, Curthoys NP: Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of the mouse kidney. J Histochem Cytochem 36:159-166, 1988. PMID: 2891746 |
29. Avner ED, Piesco NP, Sweeney WE, Ellis D: Renal epithelial development in organotypic culture. Pediatr Nephrol 2:92-99, 1988. PMID: 3153007 |
30. Avner ED, Sweeney WE, Ellis D: Congenital murine polycystic kidney disease: II. Pathogenesis of tubular cyst formation. Pediatr Nephrol 2:210-218, 1988. PMID: 2856368 |
31. Ellis D, Sothi TD, Curthoys NP, Ballou B, Avner ED: Regulation of glucocorticoid receptors and Na-K ATPase activity by hydrocortisone in proximal tubular epithelial cells. In Vitro Cell Dev Biol 24:811-816, 1988. PMID: 2900828 |
32. Morris SM, Kepka DM, Sweeney WE, Avner ED: Abundance of mRNAs encoding urea cycle enzymes in fetal and neonatal mouse liver. Arch Biochem Biophys. 269:175-180, 1989. PMID: 2464968 |
33. Ellis D, Coonrod BA, Dorman JS, Kelsey SF, Becker DJ, Avner ED, Orchard TJ: Choice of urine sample predictive of microalbuminuria in patients with insulin-dependent diabetes mellitus. Am J Kidney Dis. 13:321-328, 1989. PMID: 2705450 |
34. Avner ED, Sweeney WE, Ellis D: In vitro modulation of tubular cyst regression in murine polycystic kidney disease. Kidney Int 36:960-968, 1989. PMID: 2557482 |
35. Avner ED, Sweeney WE Jr. Polypeptide growth factors in metanephric growth and segmental nephron differentiation. Pediatr Nephrol. 1990 Jul;4(4):372-7. |
36. Avner ED, Sweeney, WE: Polypeptide growth factors in metanephric growth and segmental nephron differentiation. Pediatr Nephrol 4:372-377, 1990. PMID: 2206907 |
37. Tapper D, Watkins S, Burns M, Hickman RO, Avner ED: Comprehensive management of renal failure in infants. Arch Surg 125:1276-1281, 1990. |
38. Avner ED: Polypeptide growth factors and the kidney: a developmental perspective. Pediatr Nephrol 4:345-353, 1990. PMID: 2206902 |
39. Morris SM Jr, Sweeney WE Jr, Kepka DM, O'Brien WE, Avner ED. Localization of arginine biosynthetic enzymes in renal proximal tubules and abundance of mRNA during development. Pediatr Res. 1991 Feb;29(2):151-4. |
40. Sweeney WE, Avner ED: Intact organ culture of murine metanephros. J Tissue Cult Methods 13:163-168, 1991. |
41. McDonald R, Avner ED: Cystic disease in children. Seminars Nephrol 11:632-643, 1991. PMID: 1767136 |
42. Sweeney WE, Avner ED: Pathophysiology of renal tubular cyst formation in murine models of polycystic kidney disease. Contributions to Nephrology 97:23-34, 1992. PMID: 1633715 |
43. Sweeney WE Jr, Avner ED. Pathophysiology of renal tubular cyst formation in murine models of polycystic kidney disease. Contrib Nephrol. 1992;97:23-34. |
44. Kemper KJ, Avner ED. The case against screening urinalyses for asymptomatic bacteriuria in children. Am J Dis Child. 1992 Mar;146(3):343-6. |
45. Kemper KJ, Avner ED: The case against screening urinalysis for asymptomatic bacteriuria in children. Am J Dis Child 146:343-346, 1992. PMID: 1543183 |
46. Avner ED, Sweeney WE Jr, Nelson WJ. Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease. Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7447-51. PMCID: PMC49727 |
47. Fouser L, Avner ED: Physiology and cell biology update: Normal and abnormal nephrogenesis. Am J Kidney Dis 21:64-70, 1993. PMID: 8418629 |
48. Nauta J, Sweeney WE, Ozawa Y, Avner ED: Dual renal tubular and biliary epithelial abnormalities in a new murine model of autosomal recessive polycystic kidney disease. Pediatr Nephrol 7:163-172, 1993. PMID: 8476712 |
49. Avner ED: Renal developmental diseases. Semin Nephrol 13:427-435, 1993. PMID: 8210806 |
50. Avner ED: Epithelial polarity and differentiation in polycystic kidney disease. J Cell Science (Suppl) 17:217-222, 1993. PMID: 8144700 |
51. Ozawa Y, Nauta J, Sweeney WE, Avner ED: A new murine model of autosomal recessive polycystic kidney disease. Jap J Nephrol 35:349-354, 1993. PMID: 8341011 |
52. Moyer JH, Lee-Tischler MJ, Kwon HJ, Schrick JJ, Avner ED, Sweeney WE, Godfrey VL, Cacheiro NLA, Wilkinson JE, Woychik RP: Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. Science 264:1329-1333, 1994. PMID: 8191288 |
53. Brandt J, Fouser L, Watkins S, Zelikovic I, Tarr P, Nazar-Stewart V, Avner ED: E. coli 0157:H7 associated hemolytic uremic syndrome after ingestion of contaminated hamburgers. J Pediatr 125: 519-526, 1994. PMID: 7931869 |
54. Tapper D, Tarr P, Avner ED, Brandt J, Waldhausen J: Lessons learned in the management of hemolytic uremic syndrome in children. J Pediatr Surg 30: 158-163, 1995. |
55. Avner ED (ed): Pediatric fluid and electrolyte therapy. Pediatr Ann 24: 9-54, 1995. |
56. Avner ED: Disorders of sodium and water balance. Pediatr Ann 24: 23-30, 1995. PMID: 7715960 |
57. Avner ED: Gene time for polycystic kidney disease. Lancet 344:833-834, 1994. PMID: 7916394 |
58. Sliman GH, Winters WD, Shaw DW, Avner ED: Hypercalciuria and nephrocalcinosis in the Oculocerebrorenal Syndrome J. Urol 153: 1244-1246, 1995. PMID: 7869519 |
59. Avner ED, Chavers B, Sullivan EK, Tejani A: Renal transplantation and chronic dialysis in children and adolescents: The 1993 annual report of the North American Renal Transplant Cooperative Study. Pediatr Nephrol 9: 61-73, 1995. PMID: 7742226 |
60. Becker N, Avner ED: Congenital nephropathies and uropathies. Pediatr Clin North Amer 42: 1319-1341, 1995. PMID: 8614589 |
61. Orellana S, Avner ED: Cystic maldevelopment of the kidney. Sem Nephrol 15: 341-352, 1995. PMID: 7569413 |
62. Nauta J, Sweeney WE, Rutledge J, Avner ED: Biliary epithelial cells from mice with congenital polycystic kidney disease are hyperresponsive to epidermal growth factor. Pediatr Res 37: 755-763, 1995. PMID: 7651760 |
63. Orellana S, Sweeney WE, Neff C, Avner ED: Epidermal growth factor receptor expression is abnormal in murine polycystic kidney. Kidney Int 47:490-499. 1995. PMID: 7723235 |
64. Holleman RC, Avner ED: Renal cystic disorders. Curr Pediatr 5: 80-85, 1995. |
65. Pugh J, Sweeney WE, Avner ED: The tyrosine kinase activity of the EGF receptor in murine metanephric organ culture. Kidney Int 47: 774-781, 1995. PMID: 7752576 |
66. Holleman R, Avner ED: Clinical quiz: Hypertension in an adolescent with a hypokalemic metabolic acidosis. Pediatr Nephrol 9:783-784, 1995. PMID: 8747126 |
67. Guay-Woodford L, Muechar G, Hopkins S, Avner ED, Germino G, Guillot A, Herrin J, Holleman R, Irons D, Primack W, Thompson P, Waldo F, Lunt P, Zerres K: The severe perinatal form of Autosomal Recessive Polycystic Kidney Disease maps to chromosome 6p21.1-p12: Implications for genetic counseling. Am J Hum Genet 56: 1101-1107, 1995. PMID: 7726165 |
68. Johnson JA, Grande JP, Roche PC, Sweeney WE, Avner ED, Kumar R: 1α25 Dihydroxyvitamin D3 receptor ontogeny in fetal renal development. Am J Physiol 38:F419-F428, 1995. PMID: 7573491 |
69. Becker N, Rutledge JC, Avner ED: Clinical quiz: Acute renal failure in an adolescent with JRA. Pediatr Nephrol 9:785-787, 1995. PMID: 8747127 |
70. Foreman JW, Benson LL, Wellons M, Avner ED, Sweeney WE, Nissim IL, Nissim IT: Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester (CDE) model of cystinosis. J Am Soc Nephrol 6:269-272, 1995. PMID: 7579095 |
71. Yoder BK, Richards WG, Sweeney WE, Wilkinson JE, Avner ED, Woychik RP: Insertional mutagenesis and molecular analysis of a new gene associated with polycystic kidney disease. Proceed Assoc Amer Physicians 107: 314-323, 1995. |
72. Orellana S, Neff C, Sweeney WE, Avner ED: Novel Madin Darby canine kidney cell clones exhibit unique phenotypes in response to morphogens. In Vitro Cell Dev Biol 32:329-339, 1996. PMID: 8842747 |
73. Jabs K, Sullivan EK, Avner ED, Harmon WE: Alternate-day steroid dosing improves growth without adversely affecting graft survival of long term graft function: A report of the North American Pediatric Renal Transplant Cooperative Study. Transplantation 61:31-36. 1996. PMID: 8560569 |
74. Guay-Woodford LM, Bryda EC, Christine B, Lindsey JR, Collier WR, Avner ED, E'Eustachio P, Flaherty L. Evidence that two phenotypically distinct mouse PKD mutations, bpk and jcpk, are allelic. Kidney Int 50:1158-1165, 1996. PMID: 8887273 |
75. Yoder BK, Richards WG, Sommardahl CS, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP: Functional correction of the renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA. Kidney Int 50:1240-1248, 1996. PMID: 8887283 |
76. Wilson P, Avner ED: Renal maldevelopment of the kidney and urinary tract. Pediatr Nephrol 10:828-830, 1996. |
77. Lens XM, Onuchic LF, Wu G, Hayashi T, Daoust M, Mochizuki T, Santarina B, Stockwin JM, Mucher G, Becker J, Sweeney WE, Avner ED, Guay-Woodford L, Zerres K, Somlo S, Germino GG: An integrated genetic and physical map of the autosomal recessive polycystic kidney disease region. Genomics 41: 463-466, 1997. PMID: 9169147 |
78. Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP. Differential rescue of the renal and hepatic disease in an ARPKD mouse mutant: a new model to study the liver lesion. Amer J Pathol 150: 2231-2241, 1997. PMID: 9176412 |
79. Becker N, Avner ED, Watkins, SL: Improved outcome of young children on nightly automated peritoneal dialysis. Pediatr Nephrol 11:676-679, 1997. PMID: 9438640 |
80. Sweeney WE, Avner ED: The role of hepatocyte growth factor at progressive stages of metanephric development. In Vitro Cell & Develop Biol 34:189-194, 1997. PMID: 9542659 |
81. Sommardahl CS, Woychik RP, Sweeney WE, Avner ED, Wilkinson JE: Efficacy of taxol in the orpk mouse model of polycystic kidney disease. Pediatr Nephrol 11:728-733, 1997. PMID: 9438653 |
82. Davis ID, Oehlenschlager W, O'Riordan MA, Avner ED: Pediatric percutaneous renal biopsy: Should this procedure be performed in an outpatient setting? Pediatr Nephrol 12:96-100, 1998. PMID: 9543363 |
83. Orellana SA, Avner ED: Cell and molecular biology of kidney development. Sem Neph 18:233-243, 1998. PMID: 9613864 |
84. Davis ID, Bunchman TE, Grimm PC, Benfield MR, Briscoe DM, Harmon WH, Alexander SR, Avner ED: Pediatric renal transplantation: Indications and special considerations. A position paper from the Pediatric Committee of the American Society of Transplant Physicians. Pediatr Transplant 2:117-129, 1998. PMID: 10082443 |
85. Mucher G, Becker J, Knapp M, Buttner R, Moser M, Rudnik-Schoneborn S, Somlo S, Germino G, Onuchic L, Avner ED, Guay-Woodford L, Zerres K: Fine mapping of the autosomal recessive polycystic kidney disease locus (PKHD1) and the genes MCM, RDS, CKII-β, GSTA1 at 6p21.1-12. Genomics 48:40-45, 1998. |
86. Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU. Morphological and functional characterization of a conditionally immortalized collecting tubule cell line. Am J Physiol Renal Physiol. 1998 Nov 01;275(5):F802-F811. |
87. Brandt JR, Joseph MW, Fouser LS, Tarr PI, Zelikovic I, McDonald RA, Avner ED, McAfee NC, Watkins SL: Cholelithiasis following Escherichia coli 0157:H7-associated hemolytic uremic syndrome. Pediatr Nephrol 12:222-225, 1998. PMID: 9630042 |
88. Takacs-Jarret M, Sweeney WE, Avner ED, Cotton CU: Morphological and functional characterization of a conditionally immortalized collecting tubule cell line. Amer J Physiol 275: 802-811, 1998. PMID: 9815138 |
89. Murcia NS, Woychik RP, Avner ED: The molecular biology of polycystic kidney disease. Pediatr Nephrol 12:721-726, 1998. PMID: 9874315 |
90. Richards WG, Sweeney WE, Yoder BK, Wilkinson JE, Woychik RP, Avner ED: Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease. J Clin Invest 101:935-939, 1998. PMID: 9486961 |
91. Sweeney WE, Avner ED: Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease. Amer J Physiol 44: F387-F394, 1998. PMID: 9729511 |
92. Woychik RP, Klebig ML, Justice MJ, Magnuson TR, Avner ED: Functional genomics in the post-genome era. Mutation Research 400: 3-14, 1998. PMID: 9685569 |
93. Murcia NS, Sweeney WE, Avner ED: New insights into the molecular pathophysiology of polycystic kidney disease. Kidney Int 55:1187-1197, 1999. PMID: 10200981 |
94. Zerres K, Mucher G, Becker J, Steinkamm C, Rudnik-Schoneborn S, Heikkila P, Rapola J, Salonen R, Germino GG, Somlo S, Avner ED, Harman LA, Stockwin JM, Guay-Woodford LM: Prenatal diagnosis of autosomal recessive polycystic kidney disease (ARPKD): Molecular genetics, clinical experience and fetal morphology. Amer J Med Genet 76:137-144, 1998. PMID: 9511976 |
95. Brandt JR, Avner ED, Hickman RO, Watkins SL. Safety and efficacy of erythropoietin in children with chronic renal failure. Pediatr Nephrol 13: 143-147, 1999. PMID: 10229004 |
96. Cotton CU, Avner ED. PKD and CF: An interesting family provides insight into the molecular pathophysiology of polycystic kidney disease. Amer J Kid Dis 32: 1081-1083, 1998. PMID: 9856528 |
97. Avner ED, Woychik RP, Dell KM, Sweeney WE. Cellular pathophysiology of cystic kidney disease: Insight into future therapies. Inter J Dev Biol 43: 457-461, 1999. PMID: 10535324 |
98. Park JH, Dixit MP, Onuchic LF, Wu G, Goncharuk AN, Kneitz S, Santarina LB, Hayashi T, Avner ED, Guay-Woodford L, Zerres K, Germino GG, Somlo S. A 1 Mb BAC/PAC-based physical map of the autosomal recessive polycystic kidney disease gene (PKHD1) region on chromosome 6. Genomics 57: 249-255, 1999. PMID: 10198164 |
99. Sweeney WE, Futey L, Frost P, Avner ED. In vitro modulation of cyst formation by a novel tyrosine kinase inhibitor. Kidney Int 56: 406-413, 1999. PMID: 10432378 |
100. Avner ED. Glomerulosclerosis and hypoplasia - A common theme? Kidney Int 56:1962-1963, 1999. PMID: 10571808 |
101. Nakanishi K, Sweeney WE, Zerres K, Guay-Woodford LG, Avner ED. Proximal tubular cysts in fetal human autosomal recessive polycystic kidney disease. J Amer Soc Nephrol 11:760-763, 2000. PMID: 10752536 |
102. Nakanishi K, Sweeney WE, Avner ED. Polycystic kidney disease: Insights into future therapies. J Dev Nephrol: 8:3-9, 2000. |
103. Sweeney WE, Chen Y, Nakanishi K, Frost P, Avner ED. Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor. Kidney Int 57:33-40, 2000. PMID: 10620185 |
104. Onuchic LF, Mrug M, Lakings AL, Muecher G, Becker J, Zerres K. Avner ED, Dixit M, Somlo S, Germino GG, Guay-Woodford LM. Genomic organization of the KIAA0057 gene that encodes a TRAM-like protein and its exclusion as a polycystic kidney and hepatic disease 1 (PKHD1) candidate gene. Mammalian Genome 10: 1175-1178, 1999. PMID: 10594243 |
105. Hofmann Y, Becker J, Wright F, Avner ED, Mrug M, Guay-Woodford LM, Somlo S, Zerres K, Germino GG, Onuchic LF. Genomic structure of the gene for the human P1 protein (MCM3) and its exclusion as a candidate for autosomal recessive polycystic kidney disease. Euro J Human Gen 8: 163-166 (2000). PMID: 10780780 |
106. Nakanishi K, Sweeney WE, Avner ED. Segment-specific c-ErbB2 expression in human autosomal recessive polycystic kidney disease. J Amer Soc Nephrol 12:379-384, 2001. PMID: 11158230 |
107. Nakanishi K, Gattone II V, Sweeney WE, Avner ED. Renal dysfunction but not cystic change is ameliorated by neonatal EGF in bpk mice. Pediatr Nephrol 16:48-50, 2001. PMID: 11198603 |
108. Nakanishi K, Sweeney WE, Dell KM, Cotton C, Avner ED. Role of CFTR in autosomal recessive polycystic kidney disease. J Amer Soc Nephrol 12:719-725, 2001. PMID: 11274233 |
109. Nakanishi K, Sweeney WE, Avner ED, Murcia NS. Expression of the Oak Ridge polycystic kidney (orpk) disease gene during kidney development and maturation. Pediatr Nephrol 16:219-226, 2001. PMID: 11322368 |
110. Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU. Generation and phenotype of cell lines derived from CF and non-CF mice that carry the H-2Kb-tsA58 transgene. Am J Physiol 280:C228-C236, 2001. PMID: 11158230 |
111. Davis ID, Dell KM, Sweeney WE, Avner ED: Can progression of autosomal dominant or autosomal recessive polycystic kidney disease be prevented? Seminars in Nephrology 21:430-440, 2001. PMID: 11559884 |
112. Avner ED: Childhood ADPKD - Answers and more questions. Kidney Int 59:1979-1980, 2001. PMID: 11318972 |
113. Nakanishi K, Sweeney WE Jr, Avner ED. Segment-specific c-ErbB2 expression in human autosomal recessive polycystic kidney disease. J Am Soc Nephrol. 2001 Feb;12(2):379-384. |
114. Dell KM, Nemo R, Sweeney WE, Levin J, Frost P, Avner ED. A novel inhibitor of TNF-Alpha converting enzyme ameliorates polycystic kidney disease. Kidney Int 60:1240-1248, 2001. PMID: 11576338 |
115. Sweeney WE, Kusner L, Carlin CR, Chang S, Futey L, Cotton CU, Avner ED. Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD. Amer J Physiol 281:C1695-1705, 2001. PMID: 11600434 |
116. Onuchic LF, Mrug M, Hou X, Eggerman T, Bergmann C, Zerres K, Avner ED, Furu L, Somlo S, Nagasawa Y, Germino GG, Guay-Woodford LM. Refinement of the autosomal recessive polycystic kidney disease (PKHD1) interval and exclusion of an EF hand-containing gene as PKHD1 candidate gene. Amer J Med Genetics 110(4):346-352, 2002. PMID: 12116208 |
117. Onuchic LF, Furu L, Nagasawa Y, Hou X, Eggerman T, Ren Z, Bergmann C, Sanderek J, Esquivel E, Zeltner R, Rudnic-Schoneborn S, Mrug M, Sweeney W, Avner ED, Zerres K, Guay-Woodford LM, Somlo S, Germino GG. PKHD1, the polycystic kidney and hepatic disease 1 gene (PKHD1) encodes a novel large protein containing multiple IPT domains and PbH1 repeats. Amer J Human Genetics 70:1305-1317, 2002. PMID: 11898128 |
118. Nagasawa Y, Matthiesen S, Onuchic LF, Hou X, Bergmann C, Esquivel E, Senderek J, Ren Z, Zeltner R, Furu L, Avner ED, Moser M, Somlo S, Guay-Woodford L, Buttner R, Zerres K, Germino G. Identification and characterization of the human ARPKD gene. J Am Soc Nephrol 13:2246-2258, 2002. |
119. Wisanuyotin S, Dell KM, Vogt BA, O'Riordan MA, Avner ED, Davis ID. Complications of peritoneal dialysis in children with Eagle-Barrett Syndrome. Ped Nephrol, 18:159-163, 2003. PMID: 12579407. |
120. Drotar D, Avner ED. Critical choices in mentoring the next generation of academic pediatricians: Nine circles of hell or salvation? J of Pediatrics 142, 1-2, 2003. PMID: 12520243. |
121. Torres V, Sweeney WE, Qian Q, Harris PC, Frost P, Avner ED: EGF receptor tyrosine kinase inhibition attenuates PKD development in Han:SPRD rats. Kidney Inter 64:1573-1579, 2003. PMID: 14531789. |
122. Davis ID, Ho M, Hupertz V, Avner ED. Survival of childhood polycystic kidney disease following renal transplantation: The impact of advanced hepatobiliary disease. Ped Transplant 7:364-369, 2003. PMID: 14738296. |
123. Bayazit A, Vogt BA, Dell KM, Davis ID, Noyan A, Anarat A, Avner ED, Erhard P, Weiss M. Effect of the peritoneal dialysis prescription on pentosidine in children. Ped Nephrol 18:1049-1054, 2003. PMID: 12898376. |
124. Sweeney WE, Hamahira K, Sweeney J, Garcia-Gattell M, Frost P, Avner ED. Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability. Kidney Inter 64:1310-1319, 2003. PMID: 12969149. |
125. Grimm DH, Cai Y, Chauvet V, Rajendran V, Avner ED, Sweeney W, Somlo S, Caplan MJ. Polycystin-1 localization is a function of polycystin-2 expression in mammalian cells. J Biol Chem 278:36786-36793, 2003. PMID: 12840011. |
126. Furu L, Onuchic LF, Gharavi A, Hou X, Esquivel E, Nagasawa Y, Bergmann C, Senderek J, Avner ED, Zerres K, Germino GG, Guay-Woodford LM, Somlo S: Milder presentation of recessive polycystic kidney disease requires presence of amino acid substitution mutations. J Am Soc Nephrol 14:2004-2014, 2003. PMID: 12874454. |
127. Dell KM, Nemo R, Sweeney WE, Avner ED. EGF-Related growth factors in the pathogenesis of murine ARPKD. Kidney Inter 65:2018-2029, 2004. PMID: 15496147. |
128. Torres VE, Sweeney WE, Wang X, Qian Q, Harris PC, Frost P, Avner, ED. Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition is not protective in PCK Rats. Kidney Inter 66(5):1766-73, 2004. PMID: 15496147. |
129. Consugar M, Anderson SA, Rossetti S, Pankratz VS, Ward CJ, Torra R, Coto E, El-Youssef M, Kantarci S, Utsch B, Hildebrandt F, Sweeney WE, Avner ED, Torres VE, Cunningham JM, Harris.PC. Haplotype analysis improves molecular diagnostics of autosomal recessive polycystic kidney disease (ARPKD). Am J Kidney Dis 45(1):77-87, 2005. PMID: 15696446. |
130. Sweeney WE and Avner ED. Molecular and Cellular Pathophysiology of Autosomal Recessive Polycystic Kidney Disease. Cell Tissue Res 326:671-685, 2006. PMID: 16767405. |
131. Gunay-Aygun M, Avner ED et al. First Office of Rare Disorders (ORD)-National Institutes of Health (NIH) Workshop on Autosomal Recessive Polycystic Kidney Disease and Congenital Hepatic Fibrosis (ARPKD/CHF) Summary Statement. J Pediatr. 149 (2):159-64, 2006. PMID: 16887426. |
132. Sweeney WE, Avner ED. Renal cystic disease: new insights for the clinician. Pediatr Clin North Am 53:889-909, 2006. PMID: 17027616 |
133. Sweeney WE, von Vigier RO, Frost P, Avner ED. Src inhibition ameliorates autosomal recessive polycystic kidney disease in the BPK murine model. J Am Soc Nephrol. 19:1331-1341, 2008. PMCID: PMC2440293. |
134. Park F, Sweeney WE, Jia G, Roman RJ, Avner ED. 20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease. J Am Soc Nephrol. 19:1929-1940, 2008. PMCID: PMC2551562. |
135. Park F, Sweeney WE Jr, Jia G, Akbulut T, Mueller B, Falck JR, Birudaraju S, Roman RJ, Avner ED. Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD. Am J Physiol Renal Physiol. 2009 Mar;296(3):F575-82. PMCID: PMC2660198 |
136. Park, F, Sweeney WE, Guanggfu J, Akbulut T, Mueller B, Falck J, Birudaraju S, Roman R, Avner ED. Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD. Amer J Physiol Renal. 296:575-582, 2009. PMCID: PMC2660198. |
137. Akbulut T, Regner KR, Roman RJ, Avner ED, Falck JR, Park F. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism. Am J Physiol Renal Physiol. 2009 Sep;297(3):F662-70. PMCID: PMC2739708 |
138. Dell KM, Avner ED. Polycystic kidney disease, autosomal recessive. In: Pagon RA, Bird TC, Dolan CR, Stephens K, editors GeneReviews. [Internet] 2009. PMID: 20301501. |
139. Lau EC, Janson MM, Roesler MR, Avner ED, Strawn EY, Bick DP. Birth of a healthy infant following preimplantation PKHD1 haplotyping for autosomal recessive polycystic kidney disease using multiple displacement amplification. J Assist Reprod Genet. 2010 Jul;27(7):397-407. PMCID: PMC2922704 |
140. Sweeney WE, Avner ED. Diagnosis and management of childhood polycystic kidney disease. Pediatr Nephrol. 26 (5): 675-692.2011. PMID 21046169. |
141. Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE, Park F. Loss of activator of G protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents. FASE J. 2011 March 7. [epub ahead of print]. PMID 21343176. |
142. Liu W, Fan LX, Zhou X, Sweeney WE Jr, Avner ED, Li X. HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells. PLoS One. 2012;7(11):e49418. PMCID: PMC3496684 |
143. O'Meara CC, Hoffman M, Sweeney WE Jr, Tsaih SW, Xiao B, Jacob HJ, Avner ED, Moreno C. Role of genetic modifiers in an orthologous rat model of ARPKD. Physiol Genomics. 2012 Aug 01;44(15):741-53. PMCID: PMC3774585 |
144. McDonald RA, Avner ED. Inherited polycystic kidney disease in children. Semin Nephrol. 1991 Nov;11(6):632-42. |
145. Avner ED. Polypeptide growth factors and the kidney: a developmental perspective. Pediatr Nephrol. 1990 Jul;4(4):345-53. |
146. Morris SM Jr, Kepka DM, Sweeney WE Jr, Avner ED. Abundance of mRNAs encoding urea cycle enzymes in fetal and neonatal mouse liver. Arch Biochem Biophys. 1989 Feb 15;269(1):175-80. |
147. Avner ED, Sweeney WE Jr, Ellis D. In vitro modulation of tubular cyst regression in murine polycystic kidney disease. Kidney Int. 1989 Dec;36(6):960-8. |
148. Ellis D, Coonrod BA, Dorman JS, Kelsey SF, Becker DJ, Avner ED, Orchard TJ. Choice of urine sample predictive of microalbuminuria in patients with insulin-dependent diabetes mellitus. Am J Kidney Dis. 1989 Apr;13(4):321-8. |
149. Ellis D, Sothi TD, Avner ED. Glucocorticoids modulate renal glucocorticoid receptors and Na-K ATPase activity. Kidney Int. 1987 Oct;32(4):464-71. |
150. Ellis D, Sothi TD, Curthoys NP, Ballou B, Avner ED. Regulation of glucocorticoid receptors and Na-K ATPase activity by hydrocortisone in proximal tubular epithelial cells. In Vitro Cell Dev Biol. 1988 Aug;24(8):811-6. |
151. Curto KA, Sweeney WE, Avner ED, Piesco NP, Curthoys NP. Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney. J Histochem Cytochem. 1988 Feb;36(2):159-66. |
152. Avner ED, Sweeney WE Jr, Young MC, Ellis D. Congenital murine polycystic kidney disease. II. Pathogenesis of tubular cyst formation. Pediatr Nephrol. 1988 Apr;2(2):210-8. |
153. Avner ED, Sweeney WE Jr, Piesco NP, Ellis D. Triiodothyronine-induced cyst formation in metanephric organ culture: the role of increased Na-K-adenosine triphosphatase activity. J Lab Clin Med. 1987 Apr;109(4):441-53. |
154. Osorio AM, Thun MJ, Novak RF, Van Cura EJ, Avner ED. Silica and glomerulonephritis: case report and review of the literature. Am J Kidney Dis. 1987 Mar;9(3):224-30. |
155. Avner ED, Sweeney WE Jr, Finegold DN, Piesco NP, Ellis D. Sodium-potassium ATPase activity mediates cyst formation in metanephric organ culture. Kidney Int. 1985 Sep;28(3):447-55. |
156. Avner ED, Piesco NP, Sweeney WE Jr, Ellis D. Renal epithelial development in organotypic culture. Pediatr Nephrol. 1988 Jan;2(1):92-9. |
157. Avner ED, Studnicki FE, Young MC, Sweeney WE Jr, Piesco NP, Ellis D, Fettermann GH. Congenital murine polycystic kidney disease. I. The ontogeny of tubular cyst formation. Pediatr Nephrol. 1987 Oct;1(4):587-96. |
158. Avner ED. Renal cystic disease. Insights from recent experimental investigations. Nephron. 1988;48(2):89-93. |
159. Ellis D, Avner ED, Starzl TE. Renal failure in children with hepatic failure undergoing liver transplantation. J Pediatr. 1986 Mar;108(3):393-8. PMCID: PMC2976655 |
160. Ellis D, Avner ED. Renal failure and dialysis therapy in children with hepatic failure in the perioperative period of orthotopic liver transplantation. Clin Nephrol. 1986 Jun;25(6):295-303. |
161. Ellis D, Tran SD, Eagon PK, Avner ED. Reversible inhibition of cytosolic glucocorticoid receptors by mercurial agents. Application in the measurement of total and unoccupied receptors. J Recept Res. 1987;7(5):761-74. |
162. Avner ED, Sweeney WE Jr, Piesco NP, Ellis D. Growth factor requirements of organogenesis in serum-free metanephric organ culture. In Vitro Cell Dev Biol. 1985 May;21(5):297-304. |
163. Ellis D, Avner ED, Rosenthal JT, Taylor RJ, Young LW, Palumbi MA, Hakala TR. Renal function and somatic growth in pediatric cadaveric renal transplantation with cyclosporine-prednisone immunosuppression. Am J Dis Child. 1985 Nov;139(11):1161-7. |
164. Avner ED, Sweeney WE Jr, Piesco NP, Ellis D. Regression of genetically determined polycystic kidney disease in murine organ culture. Experientia. 1986 Jan 15;42(1):77-80. |
165. Ellis D, Avner ED, Kurs-Lasky M, Richards M, Becker DJ. Effects of improved glycemic control on microalbuminuria in adolescents with insulin-dependent diabetes mellitus. Int J Pediatr Nephrol. 1986;7(1):31-8. |
166. Avner ED, Ingelfinger JR, Herrin JT, Link DA, Marcus E, Tolkoff-Rubin NE, Russell-Getz L, Rubin RH. Single-dose amoxicillin therapy of uncomplicated pediatric urinary tract infections. J Pediatr. 1983 Apr;102(4):623-7. |
167. Ellis D, Avner ED, Transue D, Yunis EJ, Drash AL, Becker DJ. Diabetic nephropathy in adolescence: appearance during improved glycemic control. Pediatrics. 1983 May;71(5):824-9. |
168. Avner ED, Sweeney WE Jr, Ellis D. Cyst formation in metanephric organ culture induced by cis-dichlorodiammineplatinum (II). Experientia. 1983 Jan 15;39(1):74-6. |
169. Avner ED, Piesco NP, Sweeney WE Jr, Studnicki FM, Fetterman GH, Ellis D. Hydrocortisone-induced cystic metanephric maldevelopment in serum-free organ culture. Lab Invest. 1984 Feb;50(2):208-18. |
170. Ellis D, Turocy JF, Sweeney WE Jr, Avner ED. Partial characterization and ontogeny of renal cytosolic glucocorticoid receptors in mouse kidney. J Steroid Biochem. 1986 May;24(5):997-1003. |
171. Avner ED, Sweeney WE Jr, Piesco NP, Ellis D. A new model of glucocorticoid-induced metanephric maldevelopment. Experientia. 1984 May 15;40(5):489-90. |
172. Avner ED, Jaffe R, Temple T, Ellis D, Chung AE. Development of renal basement membrane glycoproteins in metanephric organ culture. Lab Invest. 1983 Mar;48(3):263-8. |
173. Avner ED, Ellis D, Jaffe R. Veno-occlusive disease of the liver associated with cysteamine treatment of nephropathic cystinosis. J Pediatr. 1983 May;102(5):793-6. |
174. Avner ED, Villee DB, Schneeberger EE, Grupe WE. An organ culture model for the study of metanephric development. J Urol. 1983 Mar;129(3):660-4. |
175. Avner ED, Harmon WE, Grupe WE, Ingelfinger JR, Eraklis AJ, Levey RH. Mortality of chronic hemodialysis and renal transplantation in pediatric end-stage renal disease. Pediatrics. 1981 Mar;67(3):412-6. |
176. Avner ED, Ellis D, Jaffe R, Bowen A. Neonatal radiocontrast nephropathy simulating infantile polycystic kidney disease. J Pediatr. 1982 Jan;100(1):85-7. |
177. Avner ED. Gene time for polycystic kidney disease. Lancet. 1994 Sep 24;344(8926):833-4. |
178. Johnson JA, Grande JP, Roche PC, Sweeney WE Jr, Avner ED, Kumar R. 1 alpha, 25-dihydroxyvitamin D3 receptor ontogenesis in fetal renal development. Am J Physiol. 1995 Sep;269(3 Pt 2):F419-28. |
179. Orellana SA, Avner ED. Cystic maldevelopment of the kidney. Semin Nephrol. 1995 Jul;15(4):341-52. |
180. Nauta J, Sweeney WE, Rutledge JC, Avner ED. Biliary epithelial cells from mice with congenital polycystic kidney disease are hyperresponsive to epidermal growth factor. Pediatr Res. 1995 Jun;37(6):755-63. |
181. Foreman JW, Benson LL, Wellons M, Avner ED, Sweeney W, Nissim I, Nissim I. Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester model of cystinosis. J Am Soc Nephrol. 1995 Aug;6(2):269-72. |
182. Pugh JL, Sweeney WE Jr, Avner ED. Tyrosine kinase activity of the EGF receptor in murine metanephric organ culture. Kidney Int. 1995 Mar;47(3):774-81. |
183. Sliman GA, Winters WD, Shaw DW, Avner ED. Hypercalciuria and nephrocalcinosis in the oculocerebrorenal syndrome. J Urol. 1995 Apr;153(4):1244-6. |
184. Fouser L, Avner ED. Normal and abnormal nephrogenesis. Am J Kidney Dis. 1993 Jan;21(1):64-70. |
185. Ozawa Y, Nauta J, Sweeney WE, Avner ED. A new murine model of autosomal recessive polycystic kidney disease. Nihon Jinzo Gakkai Shi. 1993 Apr;35(4):349-54. |
186. Nauta J, Ozawa Y, Sweeney WE Jr, Rutledge JC, Avner ED. Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease. Pediatr Nephrol. 1993 Apr;7(2):163-72. |
187. Jabs K, Sullivan EK, Avner ED, Harmon WE. Alternate-day steroid dosing improves growth without adversely affecting graft survival or long-term graft function. A report of the North American Pediatric Renal Transplant Cooperative Study. Transplantation. 1996 Jan 15;61(1):31-6. |
188. Becker N, Avner ED. Congenital nephropathies and uropathies. Pediatr Clin North Am. 1995 Dec;42(6):1319-41. |
189. Avner ED. Epithelial polarity and differentiation in polycystic kidney disease. J Cell Sci Suppl. 1993;17:217-22. |
190. Avner ED. Renal developmental diseases. Semin Nephrol. 1993 Sep;13(5):427-35. |
191. Moyer JH, Lee-Tischler MJ, Kwon HY, Schrick JJ, Avner ED, Sweeney WE, Godfrey VL, Cacheiro NL, Wilkinson JE, Woychik RP. Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. Science. 1994 May 27;264(5163):1329-33. |
192. Brandt JR, Fouser LS, Watkins SL, Zelikovic I, Tarr PI, Nazar-Stewart V, Avner ED. Escherichia coli O 157:H7-associated hemolytic-uremic syndrome after ingestion of contaminated hamburgers. J Pediatr. 1994 Oct;125(4):519-26. |
193. Guay-Woodford LM, Muecher G, Hopkins SD, Avner ED, Germino GG, Guillot AP, Herrin J, Holleman R, Irons DA, Primack W. The severe perinatal form of autosomal recessive polycystic kidney disease maps to chromosome 6p21.1-p12: implications for genetic counseling. Am J Hum Genet. 1995 May;56(5):1101-7. PMCID: PMC1801440 |
194. Avner ED, Chavers B, Sullivan EK, Tejani A. Renal transplantation and chronic dialysis in children and adolescents: the 1993 annual report of the North American Pediatric Renal Transplant Cooperative Study. Pediatr Nephrol. 1995 Feb;9(1):61-73. |
195. Avner ED. Clinical disorders of water metabolism: hyponatremia and hypernatremia. Pediatr Ann. 1995 Jan;24(1):23-30. |
196. Orellana SA, Sweeney WE, Neff CD, Avner ED. Epidermal growth factor receptor expression is abnormal in murine polycystic kidney. Kidney Int. 1995 Feb;47(2):490-9. |
197. Becker N, Rutledge JC, Avner ED. Clinical quiz. Differential diagnosis of a patient with Wegener's granulomatosis. Pediatr Nephrol. 1995 Dec;9(6):785-7. |
198. Holleman R, Avner ED. Clinical quiz. Differential diagnosis of a patient with hypertension. Pediatr Nephrol. 1995 Dec;9(6):783-4. |
199. Brandt JR, Joseph MW, Fouser LS, Tarr PI, Zelikovic I, McDonald RA, Avner ED, McAfee NG, Watkins SL. Cholelithiasis following Escherichia coli O157:H7-associated hemolytic uremic syndrome. Pediatr Nephrol. 1998 Apr;12(3):222-5. |
200. Orellana SA, Avner ED. Cell and molecular biology of kidney development. Semin Nephrol. 1998 May;18(3):233-43. |
201. Murcia NS, Sweeney WE Jr, Avner ED. New insights into the molecular pathophysiology of polycystic kidney disease. Kidney Int. 1999 Apr;55(4):1187-97. |
202. Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU. Morphological and functional characterization of a conditionally immortalized collecting tubule cell line. Am J Physiol. 1998 Nov;275(5):F802-11. |
203. Orellana SA, Neff CD, Sweeney WE, Avner ED. Novel Madin Darby canine kidney cell clones exhibit unique phenotypes in response to morphogens. In Vitro Cell Dev Biol Anim. 1996 Jun;32(6):329-39. |
204. Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP. Functional correction of renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA. Kidney Int. 1996 Oct;50(4):1240-8. |
205. Guay-Woodford LM, Bryda EC, Christine B, Lindsey JR, Collier WR, Avner ED, D'Eustachio P, Flaherty L. Evidence that two phenotypically distinct mouse PKD mutations, bpk and jcpk, are allelic. Kidney Int. 1996 Oct;50(4):1158-65. |
206. Onuchic LF, Mrug M, Lakings AL, Muecher G, Becker J, Zerres K, Avner ED, Dixit M, Somlo S, Germino GG, Guay-Woodford LM. Genomic organization of the KIAA0057 gene that encodes a TRAM-like protein and its exclusion as a polycystic kidney and hepatic disease 1 (PKHD1) candidate gene. Mamm Genome. 1999 Dec;10(12):1175-8. |
207. Park JH, Dixit MP, Onuchic LF, Wu G, Goncharuk AN, Kneitz S, Santarina LB, Hayashi T, Avner ED, Guay-Woodford L, Zerres K, Germino GG, Somlo S. A 1-Mb BAC/PAC-based physical map of the autosomal recessive polycystic kidney disease gene (PKHD1) region on chromosome 6. Genomics. 1999 Apr 15;57(2):249-55. |
208. Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP. Differential rescue of the renal and hepatic disease in an autosomal recessive polycystic kidney disease mouse mutant. A new model to study the liver lesion. Am J Pathol. 1997 Jun;150(6):2231-41. PMCID: PMC1858312 |
209. Lens XM, Onuchic LF, Wu G, Hayashi T, Daoust M, Mochizuki T, Santarina LB, Stockwin JM, Mücher G, Becker J, Sweeny WE Jr, Avner ED, Guay-Woodford L, Zerres K, Somlo S, Germino GG. An integrated genetic and physical map of the autosomal recessive polycystic kidney disease region. Genomics. 1997 May 01;41(3):463-6. |
210. Sommardahl CS, Woychik RP, Sweeney WE, Avner ED, Wilkinson JE. Efficacy of taxol in the orpk mouse model of polycystic kidney disease. Pediatr Nephrol. 1997 Dec;11(6):728-33. |
211. Becker N, Brandt JR, Sutherland TA, Avner ED, Watkins SL. Improved outcome of young children on nightly automated peritoneal dialysis. Pediatr Nephrol. 1997 Dec;11(6):676-9. |
212. Richards WG, Sweeney WE, Yoder BK, Wilkinson JE, Woychik RP, Avner ED. Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease. J Clin Invest. 1998 Mar 01;101(5):935-9. PMCID: PMC508642 |
213. Zerres K, Mücher G, Becker J, Steinkamm C, Rudnik-Schöneborn S, Heikkilä P, Rapola J, Salonen R, Germino GG, Onuchic L, Somlo S, Avner ED, Harman LA, Stockwin JM, Guay-Woodford LM. Prenatal diagnosis of autosomal recessive polycystic kidney disease (ARPKD): molecular genetics, clinical experience, and fetal morphology. Am J Med Genet. 1998 Mar 05;76(2):137-44. |
214. Sweeney WE Jr, Avner ED. The role of hepatocyte growth factor (HGF) at progressive stages of metanephric development. In Vitro Cell Dev Biol Anim. 1998 Feb;34(2):189-94. |
215. Davis ID, Oehlenschlager W, O'Riordan MA, Avner ED. Pediatric renal biopsy: should this procedure be performed in an outpatient setting? Pediatr Nephrol. 1998 Feb;12(2):96-100. |
216. Sweeney WE Jr, Avner ED. Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease. Am J Physiol. 1998 Sep;275(3):F387-94. |
217. Woychik RP, Klebig ML, Justice MJ, Magnuson TR, Avner ED. Functional genomics in the post-genome era. Mutat Res. 1998 May 25;400(1-2):3-14. |
218. Cotton CU, Avner ED. PKD and CF: an interesting family provides insight into the molecular pathophysiology of polycystic kidney disease. Am J Kidney Dis. 1998 Dec;32(6):1081-3. |
219. Murcia NS, Woychik RP, Avner ED. The molecular biology of polycystic kidney disease. Pediatr Nephrol. 1998 Nov;12(9):721-6. |
220. Davis ID, Bunchman TE, Grimm PC, Benfield MR, Briscoe DM, Harmon WE, Alexander SR, Avner ED. Pediatric renal transplantation: indications and special considerations. A position paper from the Pediatric Committee of the American Society of Transplant Physicians. Pediatr Transplant. 1998 May;2(2):117-29. |
221. Brandt JR, Avner ED, Hickman RO, Watkins SL. Safety and efficacy of erythropoietin in children with chronic renal failure. Pediatr Nephrol. 1999 Feb;13(2):143-7. |
222. Avner ED, Woychik RP, Dell KM, Sweeney WE. Cellular pathophysiology of cystic kidney disease: insight into future therapies. Int J Dev Biol. 1999;43(5):457-61. |
223. Sweeney WE, Futey L, Frost P, Avner ED. In vitro modulation of cyst formation by a novel tyrosine kinase inhibitor. Kidney Int. 1999 Aug;56(2):406-13. |
224. Avner ED. Glomerulosclerosis and hypoplasia--a common theme? Kidney Int. 1999 Nov;56(5):1962-3. |
225. Sweeney WE, Chen Y, Nakanishi K, Frost P, Avner ED. Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor. Kidney Int. 2000 Jan;57(1):33-40. |
226. Hofmann Y, Becker J, Wright F, Avner ED, Mrug M, Guay-Woodford LM, Somlo S, Zerres K, Germino GG, Onuchic LF. Genomic structure of the gene for the human P1 protein (MCM3) and its exclusion as a candidate for autosomal recessive polycystic kidney disease. Eur J Hum Genet. 2000 Mar;8(3):163-6. |
227. Nakanishi K, Sweeney WE Jr, Zerres K, Guay-Woodford LM, Avner ED. Proximal tubular cysts in fetal human autosomal recessive polycystic kidney disease. J Am Soc Nephrol. 2000 Apr;11(4):760-763. |
228. Nakanishi K, Gattone VH 2nd, Sweeney WE, Avner ED. Renal dysfunction but not cystic change is ameliorated by neonatal epidermal growth factor in bpk mice. Pediatr Nephrol. 2001 Jan;16(1):45-50. |
229. Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU. Generation and phenotype of cell lines derived from CF and non-CF mice that carry the H-2K(b)-tsA58 transgene. Am J Physiol Cell Physiol. 2001 Jan;280(1):C228-36. |
230. Nakanishi K, Sweeney WE Jr, Avner ED, Murcia NS. Expression of the orpk disease gene during kidney development and maturation. Pediatr Nephrol. 2001 Mar;16(3):219-26. |
231. Avner ED. Childhood ADPKD: answers and more questions. Kidney Int. 2001 May;59(5):1979-80. |
232. Nakanishi K, Sweeney WE Jr, Macrae Dell K, Cotton CU, Avner ED. Role of CFTR in autosomal recessive polycystic kidney disease. J Am Soc Nephrol. 2001 Apr;12(4):719-725. |
233. Dell KM, Nemo R, Sweeney WE Jr, Levin JI, Frost P, Avner ED. A novel inhibitor of tumor necrosis factor-alpha converting enzyme ameliorates polycystic kidney disease. Kidney Int. 2001 Oct;60(4):1240-8. |
234. Davis ID, MacRae Dell K, Sweeney WE, Avner ED. Can progression of autosomal dominant or autosomal recessive polycystic kidney disease be prevented? Semin Nephrol. 2001 Sep;21(5):430-40. |
235. Sweeney WE Jr, Kusner L, Carlin CR, Chang S, Futey L, Cotton CU, Dell KM, Avner ED. Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD. Am J Physiol Cell Physiol. 2001 Nov;281(5):C1695-705. |
236. Onuchic LF, Furu L, Nagasawa Y, Hou X, Eggermann T, Ren Z, Bergmann C, Senderek J, Esquivel E, Zeltner R, Rudnik-Schöneborn S, Mrug M, Sweeney W, Avner ED, Zerres K, Guay-Woodford LM, Somlo S, Germino GG. PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats. Am J Hum Genet. 2002 May;70(5):1305-17. PMCID: PMC447605 |
237. Onuchic LF, Mrug M, Hou X, Eggermann T, Bergmann C, Zerres K, Avner ED, Furu L, Somlo S, Nagasawa Y, Germino GG, Guay-Woodford LM. Refinement of the autosomal recessive polycystic kidney disease (PKHD1) interval and exclusion of an EF hand-containing gene as a PKHD1 candidate gene. Am J Med Genet. 2002 Jul 15;110(4):346-52. |
238. Torres VE, Sweeney WE Jr, Wang X, Qian Q, Harris PC, Frost P, Avner ED. EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats. Kidney Int. 2003 Nov;64(5):1573-9. |
239. Sweeney WE Jr, Hamahira K, Sweeney J, Garcia-Gatrell M, Frost P, Avner ED. Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability. Kidney Int. 2003 Oct;64(4):1310-9. |
240. Wisanuyotin S, Dell KM, Vogt BA, O'Riordan MA, Avner ED, Davis ID. Complications of peritoneal dialysis in children with Eagle-Barrett syndrome. Pediatr Nephrol. 2003 Feb;18(2):159-63. |
241. Drotar D, Avner ED. Critical choices in mentoring the next generation of academic pediatricians: nine circles of hell or salvation? J Pediatr. 2003 Jan;142(1):1-2. |
242. Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ. Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. J Biol Chem. 2003 Sep 19;278(38):36786-93. |
243. Bayazit AK, Vogt BA, Dell KM, Davis ID, Noyan A, Anarat A, Avner ED, Erhard P, Weiss MF. Effect of the peritoneal dialysis prescription on pentosidine in children. Pediatr Nephrol. 2003 Oct;18(10):1049-54. |
244. MacRae Dell K, Nemo R, Sweeney WE Jr, Avner ED. EGF-related growth factors in the pathogenesis of murine ARPKD. Kidney Int. 2004 Jun;65(6):2018-29. |
245. Torres VE, Sweeney WE Jr, Wang X, Qian Q, Harris PC, Frost P, Avner ED. Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats. Kidney Int. 2004 Nov;66(5):1766-73. |
246. Consugar MB, Anderson SA, Rossetti S, Pankratz VS, Ward CJ, Torra R, Coto E, El-Youssef M, Kantarci S, Utsch B, Hildebrandt F, Sweeney WE, Avner ED, Torres VE, Cunningham JM, Harris PC. Haplotype analysis improves molecular diagnostics of autosomal recessive polycystic kidney disease. Am J Kidney Dis. 2005 Jan;45(1):77-87. |
247. Gunay-Aygun M, Avner ED, Bacallao RL, Choyke PL, Flynn JT, Germino GG, Guay-Woodford L, Harris P, Heller T, Ingelfinger J, Kaskel F, Kleta R, LaRusso NF, Mohan P, Pazour GJ, Shneider BL, Torres VE, Wilson P, Zak C, Zhou J, Gahl WA. Autosomal recessive polycystic kidney disease and congenital hepatic fibrosis: summary statement of a first National Institutes of Health/Office of Rare Diseases conference. J Pediatr. 2006 Aug;149(2):159-64. PMCID: PMC2918414 |
248. Sweeney WE Jr, Avner ED. Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD). Cell Tissue Res. 2006 Dec;326(3):671-85. |
249. Avner ED, Sweeney WE Jr. Renal cystic disease: new insights for the clinician. Pediatr Clin North Am. 2006 Oct;53(5):889-909, ix. |
250. Sweeney WE Jr, von Vigier RO, Frost P, Avner ED. Src inhibition ameliorates polycystic kidney disease. J Am Soc Nephrol. 2008 Jul;19(7):1331-41. PMCID: PMC2440293 |
251. Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE Jr, Park F. Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents. FASEB J. 2011 Jun;25(6):1844-55. PMCID: PMC3101034 |
252. Avner ED, McDonough AA, Sweeney WE Jr. Transport, cilia, and PKD: must we in (cyst) on interrelationships? Focus on "Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease". Am J Physiol Cell Physiol. 2012 May 15;302(10):C1434-5. PMCID: PMC3362002 |
253. Liu W, Fan LX, Zhou X, Sweeney WE Jr, Avner ED, Li X. HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells. PLoS One. 2012;7(11):e49418. PMCID: PMC3496684 |
254. Kwon M, Pavlov TS, Nozu K, Rasmussen SA, Ilatovskaya DV, Lerch-Gaggl A, North LM, Kim H, Qian F, Sweeney WE Jr, Avner ED, Blumer JB, Staruschenko A, Park F. G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21462-7. PMCID: PMC3535663 |
255. Telega G, Cronin D, Avner ED. New approaches to the autosomal recessive polycystic kidney disease patient with dual kidney-liver complications. Pediatr Transplant. 2013 Jun;17(4):328-35. PMCID: PMC3663883 |
256. Zhou X, Fan LX, Sweeney WE Jr, Denu JM, Avner ED, Li X. Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease. J Clin Invest. 2013 Jul;123(7):3084-98. PMCID: PMC4101988 |
257. Fan LX, Zhou X, Sweeney WE Jr, Wallace DP, Avner ED, Grantham JJ, Li X. Smac-mimetic-induced epithelial cell death reduces the growth of renal cysts. J Am Soc Nephrol. 2013 Dec;24(12):2010-22. PMCID: PMC3839552 |
258. Sweeney WE Jr, Avner ED. Pathophysiology of childhood polycystic kidney diseases: new insights into disease-specific therapy. Pediatr Res. 2014 Jan;75(1-2):148-57. PMCID: PMC3953890 |
259. Sweeney WE Jr, Avner ED. Emerging Therapies for Childhood Polycystic Kidney Disease. Front Pediatr. 2017;5:77. PMCID: PMC5395658 |
260. Sweeney WE, Frost P, Avner ED. Tesevatinib ameliorates progression of polycystic kidney disease in rodent models of autosomal recessive polycystic kidney disease. World J Nephrol. 2017 Jul 06;6(4):188-200. PMCID: PMC5500456 |
261. Patil A, Sweeney WE Jr, Pan CG, Avner ED. Unique interstitial miRNA signature drives fibrosis in a murine model of autosomal dominant polycystic kidney disease. World J Nephrol. 2018 Sep 07;7(5):108-116. PMCID: PMC6134266 |
262. Avner ED, Satz J, Plotkin SA. Letter: Hypoglycorrachia in young infants with viral meningitis. J Pediatr. 1975 Nov;87(5):833-4. |
263. Avner ED, Ellis D, Temple T, Jaffe R. Metanephric development in serum-free organ culture. In Vitro. 1982 Aug;18(8):675-82. |
264. Davis ID, Ho M, Hupertz V, Avner ED. Survival of childhood polycystic kidney disease following renal transplantation: the impact of advanced hepatobiliary disease. Pediatr Transplant. 2003 Oct;7(5):364-9. |
265. Park F, Sweeney WE, Jia G, Roman RJ, Avner ED. 20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease. J Am Soc Nephrol. 2008 Oct;19(10):1929-39. PMCID: PMC2551562 |
266. Sweeney WE Jr, Avner ED. Diagnosis and management of childhood polycystic kidney disease. Pediatr Nephrol. 2011 May;26(5):675-92. |
267. Levy H, Jia S, Pan A, Zhang X, Kaldunski M, Nugent ML, Reske M, Feliciano RA, Quintero D, Renda MM, Woods KJ, Murkowski K, Johnson K, Verbsky J, Dasu T, Ideozu JE, McColley S, Quasney MW, Dahmer MK, Avner E, Farrell PM, Cannon CL, Jacob H, Simpson PM, Hessner MJ. Identification of molecular signatures of cystic fibrosis disease status with plasma-based functional genomics. Physiol Genomics. 2019 Jan 01;51(1):27-41. PMCID: PMC6383551 |
268. Nozu K, Sweeney WEJ, Avner ED. Fìbrocystin/polyductin and pathophysiology of autosomal recessive polycystic kidney disease Polycystic Kidney Disease: From Bench to Bedside. March 01, 2015:43-58. |
269. Sweeney WE, Gunay-Aygun M, Patil A, Avner ED. Childhood polycystic kidney disease Pediatric Nephrology, Seventh Edition. 1 January 2015:1103-1153. |
270. Avner ED, Harmon WE, Niaudet P, Yoshikawa N, Emma F, Goldstein SL. Preface Pediatric Nephrology, Seventh Edition. 1 January 2015:v-viii. |
271. Avner ED, Harmon WE, Niaudet P, Yoshikawa N, Emma F, Goldstein SL. Pediatric nephrology, seventh edition Pediatric Nephrology, Seventh Edition. 1 January 2015:1-2730. |
272. Park F, Sweeney WE, Jia G, Akbulut T, Mueller B, Falck JR, Birudaraju S, Roman RJ, Avner ED. Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD (American Journal of Physiology - Renal Physiology (2009) 296, (F575-F582) DOI: 10.1152/ajprenal.90705.2008) American Journal of Physiology - Renal Physiology. October 2009;297(4). |
273. Avner ED, Kliegman RM. Preface Pediatric Clinics of North America. October 2006;53(5). |
274. Avner ED, Kliegman RM. Preface Pediatric Clinics of North America. August 2006;53(4). |
275. Sweeney WE, Avner ED. Embryogenesis and Anatomic Development of the Kidney Fetal and Neonatal Physiology: Third Edition. December 01, 2003;2-2:1223-1229. |
276. Furu L, Onuchic LF, Gharavi A, Hou X, Esquivel EL, Nagasawa Y, Bergmann C, Senderek J, Avner E, Zerres K, Germino GG, Guay-Woodford LM, Somlo S. Milder presentation of recessive polycystic kidney disease requires presence of amino acid substitution mutations. J Am Soc Nephrol. 2003 Aug;14(8):2004-14. |
277. Nagasawa Y, Matthiesen S, Onuchic LF, Hou X, Bergmann C, Esquivel E, Senderek J, Ren Z, Zeltner R, Furu L, Avner E, Moser M, Somlo S, Guay-Woodford L, Büttner R, Zerres K, Germino GG. Identification and characterization of Pkhd1, the mouse orthologue of the human ARPKD gene. J Am Soc Nephrol. 2002 Sep;13(9):2246-58. |
278. Avner ED. Cellular Pathophysiology of Polycystic Kidney Disease: Insights into Future Therapy Japanese Journal of Nephrology. January 1999;41(3):233-235. |
279. Avner ED. Genetic disease of the kidney: Introduction Seminars in Nephrology. 1999;19(4):311. |
280. Mücher G, Becker J, Knapp M, Büttner R, Moser M, Rudnik-Schöneborn S, Somlo S, Germino G, Onuchic L, Avner E, Guay-Woodford L, Zerres K. Fine mapping of the autosomal recessive polycystic kidney disease locus (PKHD1) and the genes MUT, RDS, CSNK2 beta, and GSTA1 at 6p21.1-p12. Genomics. 1998 Feb 15;48(1):40-5. |
281. Woychik RP, Klebig ML, Justice MJ, Magnuson TR, Avner ED. Erratum: Functional genomics in the post-genome era (Mutation Research 400 (1998) (3-14) PII: 2002751098000232) Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998;422(2):367. |
282. Wilson P, Avner E. Session VIII. Renal maldevelopment of the kidney and urinary tract Pediatric Nephrology. 1996;10(6):828-830. |
283. Tapper D, Tarr P, Avner E, Brandt J, Waldhausen J. Lessons learned in the management of hemolytic uremic syndrome in children. J Pediatr Surg. 1995 Feb;30(2):158-63. |
284. Holleman RC, Avner ED. Cystic disorders of the kidney in children Current Paediatrics. June 1995;5(2):80-85. |
285. . From the Centers for Disease Control and Prevention. Update: multistate outbreak of Escherichia coli O157:H7 infections from hamburgers--Western United States, 1992-1993. JAMA. 1993 May 05;269(17):2194-6. |
286. Kemper KJ, Avner ED. The case against screening urinalyses for asymptomatic bacteriuria in children Pediatric Nephrology. April 1993;7(2):129. |
287. Sweeney WE, Avner ED. Intact organ culture of murine metanephros Journal of tissue culture methods: Tissue Culture Association manual of cell, tissue, and organ culture procedures. September 1991;13(3):163-168. |
288. Zelikovic I, Avner ED. Neonatal, congenital, and hereditary disorders of the kidney and urinary tract Current Opinion in Pediatrics. 1991;3(2):250-255. |
289. Tapper D, Watkins S, Burns M, Hickman RO, Avner E. Comprehensive management of renal failure in infants. Arch Surg. 1990 Oct;125(10):1276-81. |
290. Osorio AM, Thun MJ, Novak RF, an Cura EJ, Avner ED. Silica and Glomerulonephritis: Case Report and Review of the Literature American Journal of Kidney Diseases. 1987;9(3):224-230. |
291. Curto KA, Sweeney WE, Avner ED, Curthoys NP. Appearance of γ-glutamyltranspeptidase (γGT) during fetal development of the mouse kidney Federation Proceedings. 1985;44(5). |
292. Avner ED, Ellis D, Jaffe R. Reply The Journal of Pediatrics. December 1983;103(6):1009. |
293. Ingelfinger JR, Avner ED, Tolkoff-Rubin NE. Single dose amoxicillin (S) treatment of uncomplicated urinary tract infections (UTI) as effective as conventional therapy (C) Pediatric Research. 1981;15(4 II). |
Books, Chapters, and Reviews |
1. Spitzer A, Avner ED (Eds), Inheritance of Kidney and Urinary Tract Disease, Academic Publishers, The Netherlands, 1990. |
2. Holliday M, Barratt M, Avner ED (eds): Pediatric Nephrology, 3rd Edition, Williams and Wilkins, 1994. |
3. Barratt TM, Avner ED, Harmon W (eds): Pediatric Nephrology, 4th Edition. Lippincott, Williams and Wilkins, 1999. |
4. Avner ED, Harmon W, Niaudet P (eds): Pediatric Nephrology, 5th Edition. Lippincott, Williams and Wilkins, 2004. |
5. Avner ED, Kliegman RM (eds): Pediatric Clinics of North America, Volume 54 (4), Scientific Foundations of Clinical Practice, Part I. August 2006. |
6. Avner ED, Kliegman RM (eds): Pediatric Clinics of North America, Volume 54 (5), Scientific Foundations of Clinical Practice, Part II. October 2006. |
7. Avner ED, Harmon W, Niaudet P, Yoshikawa N (eds): Pediatric Nephrology, 6th Edition. Springer-Verlag, 2009. |
8. Avner ED, Ingelfinger JR. Renal disorders: Hematuria. In: Graef J and Cone T (Eds), Manual of Pediatric Therapeutics, 2nd edition, Little, Brown and Co., 1980, pp 205-228. |
9. Avner ED, Harmon WE, Ingelfinger JR, Levey RH, Grupe WE. Mortality of chronic hemodialysis comparable to that of renal transplantation in pediatric end-stage renal disease. Proc Clin Dial Transplant Forum 9:1-4, 1980. |
10. Avner ED, Ingelfinger JR. Special considerations in the pediatric patient. In: Rieselbach RE and Garnick ME (Eds). Cancer and the Kidney, Lea and Feibiger, 1982, pp 275-306. |
11. Avner ED, Sweeney WE, Ellis D. Serum-free organ culture of embryonic mouse metanephros. In: Sato G, Sirbasku D, and Barnes D (Eds). Cell Culture Methods for Molecular and Cell Biology, Vol. 3: Methods for Serum-Free Culture of Epithelial and Fibroblastic Cells. A.R. Liss, 1984, pp 33-43. |
12. Avner ED, Ellis D. Diuretic therapy in pediatric patients. In: Puschett JB, Greenberg A (Eds). The Diuretic Manual, Elsevier Scientific Publishing Co., 1985, pp 115-126. |
13. Ellis D, Avner ED. Fluid and electrolyte disorders in pediatric patients. In: Puschett JB (Ed), Disorders of Fluid and Electrolyte Balance: Diagnosis and Management, Churchill Livingstone, 1985, pp 217-230. |
14. Ellis D, Avner ED. Acute and chronic renal failure. In: Schwartz GR, Safar P, Stone J, Storey P, and Wagner D (Eds). Principles and Practice of Emergency Medicine, 2nd edition, W.B. Saunders, 1986, pp 129-154. |
15. Ellis D, Avner ED. Renal and genitourinary disorders in Davis H and Zitelli B (Eds). Gower Atlas of Pediatric Physical Diagnosis, Medical Publishing Ltd, 1987, pp 13.1-13.15. |
16. Avner ED. Experimental aspects of renal cystic disease. In: Murakami K, Kitagawa T, Yabuta K, Sakai T (Eds). Recent Advances in Pediatric Nephrology, Elsevier, 1987, pp 389-393. |
17. Avner ED. Growth factor requirements of nephrogenesis following natural embryonic induction. In: Murakami K, Kitagawa T, Yabuta K, Sakai T (Eds). Recent Advances in Pediatric Nephrology, Elsevier, 1987, pp 417-421. |
18. Avner ED. Polycystic kidney disease in renal explants. In: Carone F, Dobbie JW (Eds), Advances in the Pathogenesis of Polycystic Kidney Disease, pp 137-141, Baxter, 1990. |
19. Avner ED. Metanephric development in serum-free organ culture. In: Bellinger M (Ed), Dialogues in Pediatric Urology: Animal Models for the Study of Congenital Urological Disorders, 8:2-5, W. J. Miller, 1990. |
20. Avner ED, Ellis D, Ichikawa I, Yared A. Normal neonates and the maturational development of homeostatic mechanisms. In: Ichikawa I (Ed), Pediatric Textbook of Fluids and Electrolytes, Williams and Wilkins, 1990, pp 107-118. |
21. Avner ED, Hazinski TA, Dabbagh S, Ellis D. Fluid and electrolyte abnormalities in the stressed neonate. In: Ichikawa I (Ed), Pediatric Textbook of Fluids and Electrolytes, Williams and Wilkins, 1990, pp 402-414. |
22. Avner ED, McAteer JA, Evan AP. Experimental models of cysts and cystic kidneys. In: Gardner KD, Bernstein J (eds), The Cystic Kidney, Kluwer Academic Publishers, 1990, pp 55-98. |
23. Zelikovic I, Avner ED. Neonatal, congenital, and hereditary disorders of the kidneys and urinary tract. Curr Opin Pediatr 3: 250-255, 1991 Current Sciences. |
24. Avner ED. Embryogenesis and anatomical development of the kidney. In: Polin RA, Fox WW (Eds), Fetal and Neonatal Physiology, W.B. Saunders, 1991, pp 1181-1187. |
25. Ellis D, Avner ED. Acute and chronic renal failure. In: Schwartz GR, Cayten CG, Mangelsen MA, Mayer TA (eds), Principles and Practice of Emergency Medicine, 3rd edition, Lea and Ferbiger, 1992, pp 1592-1616. |
26. Avner ED. Renal hypoplasia and dysplasia. In: Burg F, Ingelfinger J, Wald E (eds), Gellis and Kagan's Current Pediatric Therapy, 14th Edition, W.B. Saunders, 1993, pp 346-347. |
27. Watkins SL, Avner ED. Renal dysplasia and renal cystic disease. In: Holliday M, Barratt M, Avner ED (eds), Pediatric Nephrology, 3rd edition, Williams and Wilkins, 1994, pp 467-490. |
28. Wilson PD, Avner ED. Cell biology of polycystic kidney disease. In: Gabow PA, Grantham JJ (eds), Proceedings of the Fifth International Workshop on Polycystic Kidney Disease, PKR Foundation, 1993, pp 99-102. |
29. Avner ED. Abnormal growth factor responses in PKD. In: Gabow PA, Grantham JJ (eds), Proceedings of the Fifth International Workshop on Polycystic Kidney Diseases, PKR Foundation, 1993, pp 106-108. |
30. Avner ED. Medullary cystic disease and medullary sponge kidney. In: Greenberg A (ed), NKF Nephrology Primer, W.B. Saunders, 1994, pp 178-181. |
31. Avner ED. Polycystic kidney disease. In: Drukker A, Grushkin A (eds), Pediatric and Adolescent Medicine: Pediatric Nephrology, Karger AG, 1994, pp 63-78. |
32. Sliman G, Avner ED. OKT3 in pediatric transplant recipients. In: Tejani A, Fine R (eds), Pediatric Renal Transplantation, Wiley, 1994, pp 291-306. |
33. Watkins SL, Avner ED. Henoch-Schonlein purpura. In: Jacobson H, Striker G, Klahr S (eds), Principles and Practice of Nephrology, 2nd edition, Mosby, 1995, pp 168-172. |
34. McDonald R, Avner ED. Murine models of polycystic kidney disease. In: Watson M, Torres VE (eds), Polycystic Kidney Disease, Oxford University Press, 1995, pp 63-87. |
35. Avner ED. The history of renal transplantation. Transpl Chron 2: 8-10, 1995. |
36. Avner ED, Sweeney WE, Orellana S. Role of growth factors in cell proliferation. In: Grantham JJ, Davidow C,Foo I, Dirks JH (eds), Forefronts in nephrology: The molecular basis of renal cystic disease. Kidney Int 47: 715-732, 1995. |
37. Avner ED. Academic pediatrics in the 21st century. Newsletter of the Northern Ohio Pediatric Society, July, 1996. |
38. Davis ID, Vogt BA, Avner ED. Renal transplantation in infants and young children. Transplant Chronicles 4: 16-18, 1996. |
39. Avner ED. Renal hypoplasia and dysplasia. In: Burg F, Ingelfinger J, Polin R, Wald E (eds), Current Pediatric Therapy 16th Edition. W.B. Saunders, 1998, pp 832-833. |
40. Avner ED. Medullary cystic disease. In: Greenberg A, Cheung AK, Coffman TM, Falk RJ, Jennette JC (eds), NKF Primer on Kidney Diseases 2nd Edition. Academic Press, 1998, pp 323-328. |
41. Avner ED. Medullary sponge kidney. In: Greenberg A, Cheung AK, Coffman TM, Falk RJ, Jennette JC (eds), NKF Primer on Kidney Diseases 2nd Edition. Academic Press, 1998, pp 343-344. |
42. Avner ED. Progressive nephropathies: Pathophysiology and potential therapies. In: Strauss J (ed), Pediatric Nephrology: Anniversary Issues - Current Concepts in Diagnosis and Management, University of Miami Press, 2000, pp 91-101. |
43. Holleman R, Avner ED. Polycystic kidney disease in children. In: Strauss J (ed), Pediatric Nephrology: Continuing Challenges, University of Miami Press, 1997, pp 3-25. |
44. Brandt J, Avner ED, Hemolytic uremic syndrome. In: Neilson E, Couser WE (eds), Immunologic Renal Diseases, Raven Press, 1997, pp 1161-1179. |
45. Avner ED. Embryogenesis and anatomic development of the kidney. In: Polin R, Fox WW (eds), Fetal and Neonatal Physiology, 2nd edition, W.B. Saunders, 1997, pp 1554-1559. |
46. Avner ED, Of mice and men: The value of mice in the study of autosomal recessive polycystic kidney disease (ARPKD). Polycystic Kidney Foundation Newsletter, 12:4-5, 1997. |
47. Avner ED. Commentary for renal transplantation, chronic dialysis, and chronic renal insufficiency in children and adolescents. The 1995 Annual Report of the North American Pediatric Renal Transplant Cooperative Study. In: Stockman JA (ed), 1998 Year Book of Pediatrics, Mosby, 1998, pp 323-324. |
48. McDonald RA, Watkins SL, Avner ED. Polycystic kidney disease. In: Barratt TM, Avner ED, Harmon W (eds), Pediatric Nephrology, 4th Edition. Lippincott, Williams and Wilkins, 1999, pp 459-474. |
49. Watkins SL, McDonald RA, Avner ED. Renal dysplasia, hypoplasia, and miscellaneous cystic disorders. In: Barratt TM, Avner ED, Harmon W (eds), Pediatric Nephrology 4th Edition. Lippincott Williams and Wilkins, 1999, pp 415-425. |
50. Vogt BA, Davis ID, Avner ED. The Kidney. In: Klaus ME, Fanaroff AF (eds), Care of the High Risk Neonate. W.B. Saunders, 2001, pp 425-446. |
51. Ellis D, Avner ED, Maino JC, Schwartz GR. Renal Failure. In: Schwartz GR, Hanke BK, Mayer TA, Cohen JS, Dunn JD, Howton JC, Isaacman DJ, Roth P, Rothrock SG, Ungar JR (eds), Principles and Practice of Emergency Medicine, 4th Edition. Williams & Wilkins, 1998, pp 33-747. |
52. Avner ED. 1998 research update in polycystic kidney disease. 9th Annual Conference on Polycystic Kidney Disease (June 1998). www.pkdcure.org. |
53. Avner ED (ed). Genetic diseases of the kidney. Sem Nephrol 19: (4), 1999. |
54. Avner ED. Introduction: Genetic diseases of the kidney. Sem Nephrol 19: (4) 311-313, 1999. |
55. Davis ID, Avner ED. Fluid and electrolyte management. In: Fanaroff AA, Martin RJ (eds), Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. Harcourt Health Sciences, 2001, pp 619-627. |
56. Davis ID, Stork JE, Avner ED. Acid-base physiology and disorders in the neonate. In: Fanaroff AA, Martin RJ (eds), Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. Harcourt Health Sciences, 2001, pp 627-634. |
57. Vogt BA, Avner ED. The kidney and the urinary tract. In: Fanaroff AA, Martin RJ (eds), Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. Harcourt Sciences, 2001, pp. 1517-1536. |
58. Avner ED. Polycystic kidney disease. In: Burg FD, Ingelfinger JR, Polin RA, Gershon A (eds), Gellis and Kagan's Current Pediatric Therapy 17. W.B. Saunders, 2002, pp 828-831. |
59. Nakanishi K, Sweeney WE, Avner ED. PKD in Childhood. In: Ito K, Asano Y, Endo H, Miterai T, Higashihara E (eds), Annual Review Kidney 2001. Chugai Igaku Co., 2001, pp 189-195. |
60. Dell KM, Avner ED. Clinical presentation and evaluation of cystic disease. In: Postlethwaite RJ, Webb NJA (eds), Clinical Paediatric Nephrology, 3rd edition, Oxford University Press, 2003, pp 329-340. |
61. Dell KM, Avner ED. Autosomal Recessive Polycystic Kidney Disease (July 2001). In: GeneClinics: Clinical Genetic Information Resource [database online]. Copyright, University of Washington, Seattle. Available at http://www.geneclinics.org. 2001. |
62. Sweeney WE, Dell KM, Cotton CU, Carlin C, Orellana SE, Avner ED. Therapeutic intervention in PKD: An update from the Rainbow Center for Childhood PKD. Polycystic Kidney Research Foundation Newsletter, 16:12, 2001. |
63. Avner ED. Medullary cystic disease. In: Greenberg AG, Cheung AK, Coffman TM, Falk RJ, Jennette JC (eds), Primer on Kidney Diseases, Third Edition. Academic Press, 2001, pp 313-316. |
64. Davis ID, Avner ED. Chapters 500-514 - Glomerular Diseases; Clinical Evaluation of the Child with Hematuria; Isolated Glomerular Diseases with Recurrent Gross Hematuria; Glomerulonephritis Associated with Infections; Membranous Glomerulopathy; Membranoproliferative (Mesangiocapillary) Glomerulonephritis; Glomerulonephritis Associated with Systemic Lupus Erythematosis; Henoch-Schonlein Purpura Nephritis; Rapidly Progressive (Crescentic) Glomerulonephritis; Goodpasture Disease; Hemolytic-Uremic Syndrome; Upper Urinary Tract Causes of Hematuria; Hematologic Diseases Causing Hematuria; Anatomic Abnormalities Associated with Hematuria; Lower Urinary Tract Causes of Hematuria. In: Behrman RE, Kliegman RM, Jensen HB (eds), Nelson Textbook of Pediatrics, 17th edition, W.B. Saunders, 2003, pp 1731-1751. |
65. Dell KM, Avner ED. Chapters 520-524 - Tubular Function; Renal Tubular Acidosis; Nephrogenic Diabetes Insipidus; Bartter/Gitelman Syndromes and Other Inherited Tubular Transport Abnormalities; Tubulointerstitial Nephritis. In: Behrman RE, Kliegman RM, Jensen HB (eds), Nelson Textbook of Pediatrics, 17th edition, W.B. Saunders, 2003, pp 1758-1761. |
66. Vogt BA, Avner ED. Chapters 515-519, 525-527 - Introduction to the Child with Proteinuria, Transient Proteinuria, Orthostatic (Postural) Proteinuria, Fixed Proteinuria, Nephrotic Syndrome, Toxic Nephropathy, Cortical Necrosis, Renal Failure. In: Behrman RE, Kliegman RM, Jensen HB (eds), Nelson Textbook of Pediatrics, 17th edition, W.B. Saunders, 2003, 1751-1757, pp 1766-1775. |
67. Sweeney WE, Avner ED. Embryogenesis and Anatomic Development of the Kidney. In: Polin RA, Fox WW, Abman SH (eds), Fetal and Neonatal Physiology, 3rd edition, W.B. Saunders, 2004, pp 1223-1228. |
68. Dell KM, McDonald R, Watkins S, Avner ED. Polycystic Kidney Disease. In: Avner ED, Harmon W, Niaudet P (eds): Pediatric Nephrology, 5th Edition. Lippincott, Williams and Wilkins, 2004, pp 675-699. |
69. Avner ED, Wilson P. Renal disease genes and their developmental implications. Proceedings of the 8th International Workshop on Developmental Nephrology. Ped Nephrol, 18:193-195, 2003. |
70. Davis ID, Avner ED. Chapters 509-523 - Glomerular Diseases; Clinical Evaluation of the Child with Hematuria; Isolated Glomerular Diseases with Recurrent Gross Hematuria; Glomerulonephritis Associated with Infections; Membranous Glomerulopathy; Membranoproliferative (Mesangiocapillary) Glomerulonephritis; Glomerulonephritis Associated with Systemic Lupus Erythematosis; Henoch-Schonlein Purpura Nephritis; Rapidly Progressive (Crescentic) Glomerulonephritis; Goodpasture Disease; Hemolytic-Uremic Syndrome; Upper Urinary Tract Causes of Hematuria; Hematologic Diseases Causing Hematuria; Anatomic Abnormalities Associated with Hematuria; Lower Urinary Tract Causes of Hematuria. In: Kliegman RM, Behrman RE, Jensen HB (eds), Nelson Textbook of Pediatrics, 18th edition, W.B. Saunders, 2007; pp 2163-2187. |
71. Dell KM, Avner ED. Chapters 529-533 - Tubular Function; Renal Tubular Acidosis; Nephrogenic Diabetes Insipidus; Bartter/Gitelman Syndromes and Other Inherited Tubular Transport Abnormalities; Tubulointerstitial Nephritis. In: Kliegman RM, Behrman RE, Jensen HB (eds), Nelson Textbook of Pediatrics, 18th edition, W.B. Saunders, 2007; pp 2197-2205. |
72. Vogt BA, Avner ED. Chapters 515-519,525-527 - Introduction to the Child with Proteinuria, Transient Proteinuria, Orthostatic (Postural) Proteinuria, Fixed Proteinuria, Nephrotic Syndrome, Toxic Nephropathy, Cortical Necrosis, Renal Failure. In: Kliegman RM, Behrman RE, Jensen HB (eds), Nelson Textbook of Pediatrics, 18th edition, W.B. Saunders, 2007; pp 2178-2184; 2189-2196. |
73. Greenbaum L, Avner E: Cystic Kidney Diseases. In: Clinical Pediatric Nephrology. K.K. Kher, |
74. S. P. Makker, and H. W. Schnaper, eds. London, Martin Dunitz. pp 329-340, 2007. |
75. Dell KM, Avner ED. Autosomal Recessive Polycystic Kidney Disease (July 2006). In: GeneClinics: Clinical Genetic Information Resource [database online]. Copyright, University of Washington, Seattle. Available at http://www.geneclinics.org. 2006. |
76. Vogt BA, Avner ED. The Kidney and the Urinary Tract. In Fanaroff AA, Martin RJ (eds) Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant, 8th Edition. Harcourt Health Sciences, 2009. |
77. Sweeney WE, Avner ED. Embryogenesis and Anatomic Development of the Kidney. In: Polin RA, Fox WW, Abman SH (eds), Fetal and Neonatal Physiology, 4th Edition. W. B. Saunders, 2009 (In Press). |
78. Dell KM, Avner ED. Autosomal Recessive Polycystic Kidney Disease (July 2008). In: GeneClinics: Clinical Genetic Information Resource [database online]. Copyright, University of Washington, Seattle. Available at http://www.geneclinics.org. 2008. |
79. Dell KM, Sweeney WE, Avner ED. Polycystic Kidney Disease. In: Avner ED, Harmon W, Niaudet P, Yoshikawa N (eds): Pediatric Nephrology, 6th Edition. Springer-Verlag, 2009; pp 849-888. |
80. Pan CG, Avner ED: Chapters 508-511;514-Introduction to Glomerular Disease; Clinical Evaluation of the Child with Hematuria: Isolated Glomerular Diseases with Recurrent Gross Hematuria; Glomerulonephritis Associated With Infections; Glomerulonephritis Associated with SLE. In: Kliegman RM, Stanton BF, St.Geme J, Schor N, Berman RE (eds), Nelson Textbook of Pediatrics, 19th edition, Elsevier, 2011 (In Press) |
81. 129-134 Van Why SK, Avner ED: Chapters 512-513;515-518-Membranous Glomerulopathry; Membranoproliferative Glomerulonephritis; Henoch-Schonlein Purpura Nephritis, Rapidly Progressive Glomerulonephritis; Goodpasture Disease; Hemolytic Uremic Syndrome. In: Kliegman RM, Stanton BF, St.Geme J, Schor N,Berman RE (eds), Nelson Textbook of Pediatrics,19th edition, Elsevier, 2011 (In Press) |
82. 135-141 Porter CC, Avner ED: Chapters 519-521;524,525,532,533-Transient Proteinuria; Orthostatic Proteinuria, Tubulointerstitial Nephritis; Toxic Nephropathy. In: Kliegman RM, Stanton BF, St.Geme J, Schor N, Berman RE (eds), Nelson Textbook of Pediatrics,19th edition, Elsevier, 2011 (In Press) |
83. 142-144 Pais P, Avner ED: Chapters 523;526,527;534-Introduction to the Child with Proteinuria; Fixed Proteinuria; Nephrotic Syndrome; Cortical Necrosis. In: Kliegman RM, Stanton BF, St.Geme J, Schor N, Berman RE (eds), Nelson Textbook of Pediatrics, 19th edition, Elsevier, 2011 (In Press) |
84. 145-149 Sreedharan R, Avner ED: Chapters 528-533;535-Tubular Function; Renal Tubular Acidosis, Nephrogenic Diabetes Insipidus; Barrter/Gitelman Syndromes and Other Inherited Tubular Transport Abnormalities; Renal Failure. In: Kliegman RM, Stanton BF, St.Geme J, Schor N, Berman RE (eds), Nelson Textbook of Pediatrics, 19th edition, Elsevier, 2011 (In Press) |
Editorials, Letters To Editor, Other |
1. Avner ED Introduction: Fluid and Electrolytes. Pediatr Ann. 1995 Jan 1;24(1):15 |
Abstracts |
1. Guay-Woodford LM, Bryda EC, Lindsay JR, Avner ED, Flaherty L: The mouse bpk mutation, a model of autosomal recessive polycystic kidney disease, and jcpk, a phenotypically distinct PKD mutation are allelic. Presented at the Society for Pediatric Research Annual Meeting, May 1996. Pediatr Res 39:361A, 1996. |
2. Richards WG, Yoder BK, Sweeney WE, Wilkinson JE, Avner ED, Woychik RP: A hypomorphic allele of the EGF-R (Waved-2) abrogates collecting duct cyst formation in a mouse polycystic kidney disease model. Presented at the American Society of Nephrology Annual Meeting, November 1996. J Amer Soc Nephrol 7:1604, 1996. |
3. Sommardahl CS, Wilkinson JE, Sweeney WE, Avner ED, Woychik RP: The effect of taxol on cystic kidney and liver lesions in the TgN737Rpw mouse model of polycystic kidney disease. Presented at the American Society of Nephrology Annual Meeting, November 1996. J Amer Soc Nephrol 7:1605, 1996. |
4. Sweeney WE, Avner ED: BPK cyst fluid contains EGF and TGF-a like peptides which are mitogenic and phosphorylate apical EGF-R. Presented at the American Society of Nephrology Annual Meeting, November 1996. J Amer Soc Nephrol 7:1606, 1996. |
5. Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP: Differential genetic rescue of the phenotype in an ARPKD mouse mutant: A new model to study the liver lesion and proximal tubule defects. Presented at the American Society of Nephrology Annual Meeting, November 1996. J Amer Soc Nephrol 7:1610, 1996. |
6. Cotton CU, Takacs-Jarrett M, Sweeney WE, Avner ED: Conditional immortalization of murine renal collecting tubule cells. Presented at the Society of General Physiology Meeting, 1996. J Gen Physiol 108: 22A, 1996. |
7. Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU: Generation of a conditionally immortalized renal cell line. Pediatr Pulm Supplement 13: A153, 1996. |
8. Avner ED, Sweeney WE, Orellana S: Abnormal epidermal growth factor receptor expression in autosomal recessive polycystic kidney disease (ARPKD). Presented at the 6th International Workshop on Developmental Nephrology, Airle, VA 1995. Pediatr Nephrol 10: C180, 1996. |
9. Orellana SA, Winkler DJ, Avner ED: Prostaglandin E1 and serum modulate Madin Darby canine kidney cell responses to hepatocyte growth factor. Presented at the 6th International Congress on Cell Biology and 36th American Society for Cell Biology Annual Meeting, December 1996. Mol Biol of the Cell 7: 114a, 1996. |
10. Jones B, Yoder BK, Sweeney WE, Avner ED, Wilkinson JE, Woychik RP. Pattern of expression of the TG737 gene in the postnatal developing kidney. Presented at the American Society of Nephrology Annual Meeting, November, 1997, J Amer Soc Nephrol, 8:1729, 1997. |
11. Yoder BK, Wilkinson JE, Avner ED, Woychik RP. The TG737 protein interacts with polycystin (PKD1) and proteins controlling epithelial polarity, EGFR stability and cellular differentiation. Presented at the American Society of Nephrology Annual Meeting, November, 1997, J Amer Soc Nephrol 8:1783, 1997. |
12. Woychik RP, Murcia N, Yoder BK, Richards WG, Wilkinson JE, Dunlap J, Sweeney WE, Avner ED. Analysis of the expression and function of the TG737 polycystic kidney gene during mammalian development. Presented at the American Society of Nephrology Annual Meeting, November, 1997, J Amer Soc Nephrol 8:1779, 1997. |
13. Sweeney WE, Futey L, Cotton CC, Avner ED. Isolation and characterization of conditionally immortalized principal cells from the BPK model of ARPKD. Presented at the American Society of Nephrology Annual Meeting, November 1997, J Amer Soc Nephrol 8:1761, 1997. |
14. Ward DT, Sweeney WE, Avner ED, Harris HW. Purified apical membrane endosomes from rat kidney inner medullary collecting duct contain endogenous membrane-bound tyrosine kinase (TK) and phosphatase (TP) activities. Pediatr Res 43:315A, 1998. |
15. Avner ED. Cellular pathophysiology of polycystic kidney disease. Presented at the 11th Congress of the International Pediatric Nephrology Association meeting, September, 1998, Ped Nephr 12:C47, 1998. |
16. Sweeney WE, Murcia N, Jones B, Woychik RP, Avner ED. Expression of TG737 gene in developing kidney. Presented at the American Society of Nephrology Annual Meeting, October, 1998, J Amer Soc Nephrol 9:1952, 1998. |
17. Sweeney WE, Avner ED. Proximal tubular cysts in fetal human ARPKD. Presented at the American Society of Nephrology Annual Meeting, October, 1998, J Amer Soc Nephrol 9:1953, 1998. |
18. Sweeney WE, Avner ED, Elmer HL, Cotton CU. CFTR is required for cAMP-dependent in vitro renal cyst formation. Presented at the American Society of Nephrology Annual Meeting, October, 1998, J Amer Soc Nephrol 9:1954, 1998. |
19. Nakanishi K, Sweeney WE, Avner ED. Segment specific C-erb B-2 expression in human autosomal recessive polycystic kidney disease (ARPKD). Presented at the American Society of Nephrology Annual Meeting, November, 1999, J Amer Soc Nephrol 10:2127, 1999. |
20. Nakanishi K, LI L, Wu G, Sweeney WE, Somlo S, Avner ED. Characterization of cyst development and growth in Pkd2WS25/- mice. Presented at the American Society of Nephrology Annual Meeting, November, 1999, J Amer Soc Nephrol 10:2125, 1999. |
21. Harari A, Sweeney WE, Magnuson T, Avner ED. Renal development and function in epidermal growth factor receptor (EGFR) null mice. Presented at the American Society of Nephrology Annual Meeting, November, 1999, J Amer Soc Nephrol 10:2106, 1999. |
22. Nakanishi K, Gattone II V, Sweeney WE, Avner ED. Effect of exogenous epidermal growth factor (EGF) on polycystic kidney disease (PKD) in bpk cystic mice. Presented at the American Society of Nephrology Annual Meeting, November, 1999, J Amer Soc Nephrol 10:2126, 1999. |
23. Onuchik LF, Hofmann Y, Mrug M, Becker J, Dixit MP, Avner ED, Somlo S, Zerres K, Guay-Woodford LM, Germino GG - ARPKD Consortium. Genomic structure and exclusion of two candidate genes for the PKHD1 locus and three new polymorphic markers within the critical interval. Presented at the American Society of Nephrology Annual Meeting, November, 1999, J Amer Soc Nephrol 10:2133, 1999. |
24. Dell KM, Sweeney WE, Frost P, Levin J, Avner ED. Treatment with a novel inhibitor of transforming growth factor-alpha (TGF-α) secretion ameliorates disease in murine autosomal recessive polycystic kidney disease. Presented at the American Society of Nephrology Annual Meeting, October 2000, J Amer Soc Nephrol 11:388, 2000. |
25. Nakanishi K, Sweeney WE, Dell KM, Cotton CU, Avner ED. Cystic fibrosis transmembrane conductance regulator (CFTR) activity is not required for cyst formation in murine autosomal recessive polycystic kidney disease (ARPKD) mouse model. Presented at the American Society of Nephrology Annual Meeting, October, 2000, J Amer Soc Nephrol 11:395, 2000. |
26. Corsillo L, Carlin C, Sweeney WE, Avner ED. Phenotypic Analysis of Conditionally Immortalized Principal Cells Isolated from the BPK Murine Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD). Presented at the American Society of Nephrology Annual Meeting, October, 2000, J Amer Soc Nephrol 11:388, 2000. |
27. Kusner L, Carlin C, Sweeney WE, Avner ED. Phenotypic analysis of conditionally immortalized principal cells isolated from the BPK murine model of ARPKD. Presented at the Annual Meeting of the American Society for Cell Biology, December 2000, Mol Biol Cell 11:489a, 2000. |
28. Hamahira K, Sweeney WE, Dell KM, Frost P, Avner ED. Treatment with a second-generation tyrosine kinase inhibitor (EKB-569) alone or in combination with an inhibitor of TGF-α secretion ameliorates cyst progression in murine ARPKD. Presented at the American Society of Nephrology Annual Meeting, October 2001. Amer Soc Nephrol 12:536A, 2001. |
29. Dell KM, Nemo R, Sweeney WE, Avner ED. Expression of heparin-binding EGF and amphiregulin in murine ARPKD. Presented at the American Society of Nephrology Annual Meeting, October 2001.J Amer Soc Nephrol 12:534A, 2001. |
30. Wang X, Sweeney WE, Lager DJ, Harris PC, Frost P, Avner ED, Torres VE. The intraperitoneal administration of EKI-785 has opposing effects on the development of polycystic kidney disease in Han:SPRD and PCK rats. Presented at the American Society of Nephrology Annual Meeting, October 2001. J Amer Soc Nephrol 12:547A, 2001. |
31. Onuchik LF, Furu L, Nagasawa Y, Mrug M, Eggerman T, Bergmann C, Sweeney WE, Avner ED, Zerres K, Guay-Woodford LM, Somlo S, Germino GG, ARPKD Consortium. Refinement of the PKHD1 interval and analysis of candidate expressed sequences. Presented at the American Society of Nephrology Annual Meeting, October, 2001.J Amer Soc Nephrol 12:543A, 2001. |
32. 9, Dell KM, Vogt BA, O'Riordan MA, Avner ED, Davis ID. Complications of peritoneal dialysis (PD) in Eagle-Barrett syndrome (EBS). Presented at the Pediatric Academic Societies Annual Meeting, 2002, Ped Research, 51:433A, 2002. |
33. Dell KM, Nemo R, Sweeney WE, Avner ED. Evidence for a role of multiple epidermal growth factor receptor (EGFR) ligands in the pathogenesis of ARPKD. Presented at the Pediatric Academic Societies Annual Meeting, 2002, Ped Research, 51:421A, 2002. |
34. Hamahira K, Sweeney WE, Gatrell-Garcia M, Dell KM, Frost P, Avner ED. Tyrosine kinase inhibitor (EKB) alone or in combination with an inhibitor of TGF-α secretion ameliorates cyst progression in murine ARPKD. Presented at the Pediatric Academic Societies Annual Meeting, 2002, Ped Research, 51:422A, 2002. |
35. Sweeney WE, Chang S, Jelinsky S, Brown G, Slocum D, Frost P, Avner ED. Expression profiling of normal and cystic collecting tubules in the BPK murine model of ARPKD. Presented at the American Society of Nephrology Annual Meeting, October, 2002. J Amer Soc Nephrol 13:117A, 2002. |
36. Hamahira K, Sweeney WE, Avner ED. Role of apoptosis and proliferation on cyst formation in the BPK model of ARPKD. Presented at the American Society of Nephrology Annual Meeting, October, 2002. Presented at the American Society of Nephrology Annual Meeting, October, 2002. J Amer Soc Nephrol 13:112A, 2002. |
37. Dell KM, Nemo R, Sweeney WE, Avner ED. Abnormalities in the heparin-binding EGF/ErbB4/EGFR axis in murine ARPKD. Presented at the American Society of Nephrology Annual Meeting, October, 2002. J Amer Soc Nephrol 13:107A, 2002. |
38. Grimm D, Praetorius H, Cai Y, Geng L, Zeltner R, Sweeney WE, Avner ED, Somlo S, Spring K, Caplan M. A role for polycystin-2 in the cilium mechanostimulation pathway. Presented at the American Society of Nephrology Meeting, October, 2002. J Amer Soc Nephrol 13:47A, 2002. |
39. Geng L, Nishimura S, Cai Y, Velazquez H, Tian X, Wu G, Sweeney WE, Avner ED, Somlo S. Cells derived from mouse kidney retain epithelial properties despite loss or over-expression of polycystin-2. Presented at the American Society of Nephrology Annual Meeting, October, 2002. J Amer Soc Nephrol 13:115A 2002. |
40. Nagasawa Y, Mathiessen S, Onuchic L, Hou X, Esquivel E, Ren Z, Zeltner R, Bregmann C, Furu L, Avner ED, Moser M, Somlo S, Guay-Woodford L, Buettner R, Zerres K, Germino G. Identification and characterization of mouse Pkhd1. Presented at the American Society of Nephrology Annual Meeting, October 2002. J Amer Soc Nephrol 13:111A, 2002. |
41. von Vigier RO, Sweeney WE, Avner ED. Segment-specific markers of the developing rat nephron. Presented at the Pediatric Academic Societies Annual Meeting, 2003. Ped Research 53:520A, 2003. |
42. Dell KM, Nemo R, Sweeney WE, Avner ED. Transforming growth factor-alpha is not required for cystogenesis in ARPKD. Presented at the Pediatric Academic Societies Annual Meeting, 2003. Ped Research 53:516A, 2003. |
43. Sweeney WE, Chang S, Frost P, Avner ED. Identification of novel therapeutic targets through expression profiling of control and cystic principal cells in the BPK murine model of ARPKD. Presented at the Pediatric Academic Societies Annual Meeting, 2003. Ped Research 53:516A, 2003. |
44. von Vigier RO, Sweeney WE, Frost P, Avner ED. Inhibition of c-Src ameliorates cyst progression in murine ARPKD. Presented at the American Society of Nephrology Annual Meeting, 2003. J Amer Soc Nephrol 14:110A, 2003. |
45. von Vigier RO, Sweeney WE, Duzova A, Carlin CR, Avner ED. Characterization of PKHD1 expression in murine and human ARPKD. Presented at the American Society of Nephrology Annual Meeting, 2003. J Amer Soc Nephrol 14:362, 2003. |
46. Torres VE, Sweeney WE, Wang X, Qian Q, Harris PC, Frost P, Avner ED. Inhibition of epidermal growth factor receptor tyrosine kinase activity worsens in polycystic kidney disease in PCK rats. Presented at the American Society of Nephrology Annual Meeting, 2003. J Amer Soc Nephrol 14:109A, 2003. |
47. Sweeney WE, von Vigier R, Carlin CR, Punashthiti R, Ward C, Harris P, Avner ED. Characterization of PKHD1 Expression in Murine and Human ARPK. Presented at the Pediatric Academic Societies Annual Meeting 2004. Ped Research 55:574A, 2004. |
48. von Vigier RO, Sweeney WE, Murcia NS, Frost P, Avner ED. Receptor Tyrosine Kinase Inhibition attenuates Hepatobiliary Abnormalities in a murine model of Autosomal Recessive Polycystic Kidney Disease. Presented at The American Society of Nephrology Annual Meeting, 2004. J Amer Soc Nephrol 15:212A, 2004. |
49. Sweeney WE, Avner ED. "New Therapies for PKD: From Bench to Bedside" presented at The American Society of Nephrology Annual Meeting, 2004. J Amer Soc Nephrol 15:89A, 2004. |
50. Sweeney WE, Frost P, Avner ED. Inhibition of c-Src Ameliorates Cyst Progression in the PCK Rat. Presented at The Pediatric Academic Societies Annual Meeting, 2005. Washington, D.C. Ped Research 57:1509, 2005. |
51. Sweeney WE, Donohoe DL, Avner ED. Inhibition of ErbB2 Decreases c-Src Activity and Ameliorates Renal and Biliary Cystic Abnormalities in the PCK Rat. J Amer Soc Nephrol 16:225A, 2005. |
52. Sweeney WE, Donohoe DL, Gibbons J, Avner ED. A dual c-Src and c-Abl inhibitor decreases hepatic and renal fibrosis in an orthologous model of autosomal recessive polycystic kidney disease (ARPKD). Presented at The Pediatric Academic Societies Meeting, 2006. San Francisco, California. Ped Research 59:149 (#4804.40), 2006. |
53. Sweeney WE, Donohoe DL, Gibbons J, Avner ED. Pan-ErbB2 Receptor Inhibition Decreases Hepatic and Renal Fibrosis in an Orthologous Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD). Presented at The Pediatric Academic Societies Meeting, 2006. San Francisco, California. Ped Research 59:149 (#4804.41), 2006 |
54. Sweeney WE, Donohoe DL, Avner ED. Therapeutic Potential of pp60(cSrc) Inhibition in Autosomal Dominant Polycystic Kidney Disease (ADPKD). Presented at the American Society of Nephrology Annual Meeting, 2006, San Diego, California. J Amer Soc Nephrol 17:778A, 2006. |
55. Sweeney WE, Park F, Donohoe DL, Avner ED. The Role of 20-HETE. An Arachidonic Acid Metabolite on Cellular Proliferation in Autosomal Recessive Polycystic Kidney Disease (ARPKD). Presented at the Annual Meeting of the Pediatric Academic Societies, Toronto, Canada, 2007. Ped Research 61:197 (#7918.9), 2007. |
56. Elliott J, Israeli S, Sweeney WE, Avner ED, Wilson P. c-Src is Effective as Therapy for ADPKD. American Society of Nephrology Annual Meeting. San Francisco. November 2007. J Am Soc Nephrol 18: 364A, 2007 |
57. Park F, Sweeney WE, Jia G, Roman RJ, Avner ED. Contribution of cytochrome P450 metabolites to the abnormal proliferation of renal epithelial cells in a murine model of PKD. American Society of Nephrology Annual Meeting. San Francisco, California. November 2007. J Am Soc Nephrol 18: 129A, 2007 |
58. Park F, Sweeney WE, Avner, ED. Chronic blockade of 20-HETE production attenuates cyst formation in a rodent model of Autosomal Recessive Polycystic Kidney Disease. Presented at the Pediatric Academic Societies, Honolulu, Hawaii. May 2008 |
59. Moreno Quinn C, Sweeney WE, Lazar J, Jacob, H, Avner ED. Development of a Rat Model of ARPKD to Study Genetic Modifier Loci. Presented at the American Society of Nephrology Annual Meeting, Philadelphia, Pennsylvania. Poster Session (#F-PO1119), November 2008. |
60. Park F, Jia G, Akbulut T, Sweeney WE, Avner ED. Chronic Inhibition of Angiotensin Converting Enzyme Improves Renal Function. Presented at the American Society of Nephrology Annual Meeting, Philadelphia, Pennsylvania. Poster Session (#SA-PO2402), November 2008. |
61. Nadella R, Blumer JB, Qian F, Sweeney WE, Avner ED, Wilson PD, Lanier SM, Park F. Aberrant Expression of AGS3 in Genetic Models of Polycystic Kidney Disease. Presented at the American Society of Nephrology Annual Meeting, San Diego, California. Poster Session (#F-PO1660) October 2009. |
62. Sweeney WE, Nozu K, Peters DJM, Avner ED. Characterization of a Hypomorphic Pkd1 Mouse Model of ADPKD. Abstract (3481) Presented at the Renal Week 2010 of the American Society of Nephrology, Denver, Colorado. November 2010. |
63. Sweeney WE, Nozu K, Frost P, Schwasinger E, Avner ED. Multi-kinase inhibition effectively ameliorates renal cystic disease in preclinical models of PKD. Abstract - to be presented at the 2011 Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference, Saxtons River, Vermont. June 2011. |
64. O'Meara C, Sweeney WE, Hoffman M, Yeo NC, Tsaih SW, Lazar J, Jacob HJ, Avner ED, Moreno C. Role of genetic modifiers in an orthologous model of ARPKD. Abstract - to be presented at the 2011 Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference, Saxtons River, Vermont. June 2011. |
65. Li X, Avner ED. Abstract - to be presented at the 2011 Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference, Saxtons River, Vermont. June 2011. |
