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CURRICULUM VITAE

Ellis D. Avner MD
Professor
Department of Pediatrics
Division of Nephrology

OFFICE ADDRESS:
Translational and Biomedical Research Center
8701 Watertown Plank Rd
Milwaukee, WI 53226

EDUCATION:
1966 - 1970 A. B. Princeton University, Princeton, NJ
1966 - 1970 AB - Religion, Princeton University, Princeton, NJ
1971 - 1975 M.D. University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
1971 - 1975 MD, University of Pennsylvania School of Medicine, Philadelphia, PA

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
1975 - 1978 Internship/Residency, Pediatrics, (PL1-PL3), Children's Hospital, Boston, MA
1975 - 1978 Internship/Residency, Children's Hospital; Boston, Massachusetts
1978 - 1980 Fellowship, Children's Hospital, Pediatric Nephrology, Boston, MA
1978 - 1980 Fellowship, Children's Hospital, Human Reproduction and Reproductive Biology, Boston, MA
1978 - 1980 Fellowship, Pediatric/Nephrology, Children's Hospital, Boston, MA
1978 - 1980 Laboratory of Human, Developmental Biology, Reproduction and Reproductive Biology, Boston, MA
APPOINTMENTS AND POSITIONS
APPOINTMENTS AND POSITIONS
APPOINTMENTS AND POSITIONS

MILITARY SERVICE:
None

FACULTY APPOINTMENTS:
07/01/1980 - 06/30/1986 Assistant Professor, Pediatrics, Nephrology, University of Pittsburgh School of Medicine, Pittsburgh, PA
1980 - 1986 Assistant Professor, Pediatrics, University of Pittsburgh School of Medicine
07/01/1986 - 06/30/1988 Associate Professor, Pediatrics, Nephrology, University of Pittsburgh School of Medicine, Pittsburgh, PA
1986 - 1988 Associate Professor, Pediatrics, University of Pittsburgh School of Medicine
11/01/1988 - 06/30/1995 Professor, Pediatrics, Nephrology, University of Washington School of Medicine, Seattle, WA
1988 - 1995 Professor, Pediatrics, University of Washington School of Medicine
07/01/1995 - 06/30/2004 Gertrude Lee Chandler Tucker Professor and Chairman, Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH
1995 - 2004 Gertrude Lee Chandler Tucker Professor and Chairman, Department of Pediatrics
07/01/2004 - 03/01/2015 Professor, Pediatrics, Nephrology, Medical College of Wisconsin, Milwaukee, WI
07/01/2004 - 03/01/2015 Associate Dean for Research, Medical College of Wisconsin, Milwaukee, WI
2004 - 2012 Associate Dean for Research, Medical College of Wisconsin
2004 - 2015 Professor, Pediatrics (Nephrology), Medical College of Wisconsin
2004 - 2005 Adjunct Professor, Case Western Reserve University School of Medicine
07/01/2007 - 03/01/2015 Professor, Physiology, Medical College of Wisconsin, Milwaukee, WI
07/01/2007 - 03/15/2015 Co-Director, Clinical and Translational Science Institute, Medical College of Wisconsin, Milwaukee, WI
2007 - 2015 Professor, Physiology, Medical College of Wisconsin
2007 - 2011 Co-Director, Clinical and Translational Science Institute, Medical College of Wisconsin
07/01/2008 - 03/01/2015 Adjunct Professor, Health Sciences, Marquette University, Milwaukee, WI
07/01/2008 - 03/01/2015 Adjunct Professor, Marine and Freshwater Biomedical Sciences, University of Wisconsin, Milwaukee, Milwaukee, WI
2008 - 2015 Marine and Freshwater Biomedical Sciences Center (MFBSC) Affiliate of the Great Lakes Water Institute, University of Wisconsin, Milwaukee
2008 - 2015 Adjunct Professor, Marquette University, Milwaukee, Wisconsin
07/01/2009 - 03/01/2015 Adjunct Professor, Electrical Engineering and Computing, Milwaukee School of Engineering, Milwaukee, WI
03/01/2015 - Present Emeritus Professor, Pediatrics and Physiology, Nephrology, Medical College of Wisconsin, Milwaukee, WI
2015 - Present Emeritus Professor, Pediatrics and Physiology, Medical College of Wisconsin
Case Western Reserve University School of Medicine

ADMINISTRATIVE APPOINTMENTS:
1982 - 1988 Utilization Review Committee, Children's Hospital of Pittsburgh
1983 - 1988 Resident Selection Committee, Children's Hospital of Pittsburgh
1983 - 1988 Animal Research and Care Committee, Children's Hospital of Pittsburgh
1984 - 1988 Chairman, Animal Research and Care Committee, Children's Hospital of Pittsburgh
1985 - 1988 Chairman, Resident Selection Committee, Children's Hospital of Pittsburgh
1986 - 1988 Research Advisory Committee, Children's Hospital of Pittsburgh
1986 - 1988 Career Counseling Committee, University of Pittsburgh School of Medicine
1986 - 1988 Career Counseling Committee, University of Pittsburgh School of Medicine
1987 - 1988 Vice-Chairman, Research Advisory Committee, Children's Hospital of Pittsburgh
1988 - 1995 Director, Seattle, Division of Nephrology, Children's Hospital and Medical Center
1989 - 1995 Resident Selection Committee, Children's Hospital & Medical Center
1989 - 1995 Research Advisory Committee, Children's Hospital and Medical Center
1990 - 1995 Executive Committee on Transplantation, Children's Hospital and Medical Center
1990 - 1992 Chronic Care Task Force, Children's Hospital and Medical Center
1991 - 1993 Committee on Issues in Biomedical Research Integrity, University of Washington
1991 - 1995 Faculty Council on Scientific Affairs, University of Washington
1991 - 1995 Faculty Senator, University of Washington
1991 - 1993 Committee on Issues in Biomedical Research Integrity, University of Washington
1991 - 1995 Faculty Senator, University of Washington
1991 - 1995 Faculty Council on Scientific Affairs, University of Washington
1991 - 1994 Chairman, Animal Care and Use Committee, Children's Hospital and Medical Center
1992 - 1995 Regular Lecturer, Pediatrics 512P: Seminars in Human Embryology and Teratology
1992 - 1995 Regular Lecturer, Pediatrics 512P: Seminars in Human Embryology and Teratology
1993 - 1995 Chairman, Fellowship Funding Committee Children's Hospital and Medical Center
1993 - 1995 Contracts Committee, Children's University Medical Group
1993 - 1995 Quality Improvement/Peer Review Committee, Children's Hospital and Medical Center
1993 - 1995 Managed Care Committee, Department of Medicine, Children's Hospital and Medical
1994 - 2004 Co-Chair, Reaggregation Design Team, Children's Hospital and Medical Center
1994 - 1995 Regional Outreach Task Force, Children's Hospital and Medical Center
1995 - 2004 Member, Executive Committee, Case Western Reserve University School of Medicine
1995 - 2004 Chairman, Children's Research Foundation, Cleveland, Ohio
1995 - 2004 Chairman, Children's Research Foundation
1995 - 2004 Member, Executive Committee, Case Western Reserve University School of Medicine
1995 - 2004 Director of Pediatrics, Rainbow Babies and Children's Hospital and University Hospitals of Cleveland
1995 - 1998 Member, Board of Directors, University Faculty Practice Association, University Hospitals of Cleveland
1995 - 2004 University Primary Care Physicians / University Faculty Practice Association Liaison Committee, University Hospitals of Cleveland
1995 - 2004 Member, Council of Clinical Chairs, University Hospitals of Cleveland
1995 - 2004 Executive Committee, Clinical Council, University Hospitals of Cleveland
1995 - 2004 Member, Clinical Council, University Hospitals of Cleveland
1995 - 2004 Member, Clinical Leadership Advisory Committee, University Hospitals of Cleveland
1996 - 1998 Executive Committee, University Faculty Practice Association
1996 - 2004 Member, Honorary Degree Committee, Case Western Reserve University
1996 - 2002 Member, Strategic Planning Committee, Office of the Dean, Case Western Reserve University School of Medicine
1996 - 2003 Member, Clinical Council Credentialing Subcommittee, University Hospitals of Cleveland
1996 - 1998 Executive Committee, University Faculty Practice Association
1996 - 2004 Member, Honorary Degree Committee, Case Western Reserve University
1996 - 2002 Member, Strategic Planning Committee, Office of the Dean, Case Western Reserve University School of Medicine
1997 - 2004 Member, Minority Faculty Development Committee, University Hospitals of Cleveland
1997 - 1998 Chair, Department of Medicine Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Richard A. Walsh named Chairman, 1998)
1997 - 1998 Chair, Department of Medicine Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Richard A. Walsh named Chairman, 1998)
1998 - 2001 Member, Department of Reproductive Biology Chair Search Committee, Case Western Reserve University School of Medicine (Dr. James Liu named Chairman, 2001)
1998 - 2004 Member, Tenure Compensation Committee, Case Western Reserve School of Medicine
1998 - 2004 Member, Tenure Compensation Committee, Case Western Reserve School of Medicine
1998 - 2003 Member, Internal Affiliation Committee, University Hospitals of Cleveland
1998 - 2001 Member, Department of Reproductive Biology Chair Search Committee, Case Western Reserve University School of Medicine (Dr. James Liu named Chairman, 2001)
1999 - 2001 Member, Department of Family Medicine Chair Search Committee, Case Western Reserve University School of Medicine (Dr. George Kikano named Chairman, 2001)
1999 - 2004 Member, Program Advisory Committee, Howard Hughes Medical Institute Biomedical Research Support Program, Case Western Reserve University School of Medicine
1999 - 2000 Chair, Department of Psychiatry Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Pedro Delgado named Chairman, 2000)
1999 - 2001 Member, Faculty Council (University Hospitals of Cleveland representative), Case Western Reserve University School of Medicine
1999 - 2004 Member, Program Advisory Committee, Howard Hughes Medical Institute Biomedical Research Support Program, Case Western Reserve University School of Medicine
1999 - 2000 Chair, Department of Psychiatry Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Pedro Delgado named Chairman, 2000)
1999 - 2001 Member, Faculty Council (University Hospitals of Cleveland representative), Case Western Reserve University School of Medicine
1999 - 2001 Member, Department of Family Medicine Chair Search Committee, Case Western Reserve University School of Medicine (Dr. George Kikano named Chairman, 2001)
1999 - 2004 Member, Ad Hoc Committee on Safety of Polyvinylchloride/Phthalates, University
1999 - 2003 Policy Advisory Committee, Research Institute, University Hospitals of Cleveland
1999 - 2003 Space Planning Committee, Research Institute, University Hospitals of Cleveland
1999 - 2003 Member (Alternate), Executive Board, University Hospitals Faculty Services
1999 - 2003 Member, Operational Advisory Committee, University Hospital Faculty Services
1999 - 2004 Member, Mary B. Lee Endowment Fund Committee, University Hospitals of Cleveland
2000 - 2003 Member, Conflict of Interest Policy Development Committee, University Hospitals Research Institute
2000 - 2004 Member, Clinical Research Scholars Program Advisory Committee, Case Western
2000 - 2004 Chair, Educational and Research Mission Workgroup, University Hospitals of Cleveland
2000 - 2003 Member, Quality Monitoring Council, University Hospitals of Cleveland
2000 - 2003 Member, Performance Indicators Advisory Committee, University Hospitals of Cleveland
2000 - 2004 Member, CWRU/UHC Research and Intellectual Property Task Force, University Hospitals of Cleveland
2000 - 2003 Member, Executive Committee, University Hospitals Research Institute
2000 - 2004 Member, Clinical Research Scholars Program Advisory Committee, Case Western
2001 - 2004 Co-Chair, Department of Pathology Chair Search Committee, Case Western Reserve University School of Medicine
2001 - 2004 Member, Committee on Faculty Tenure, Case Western Reserve University School of
2001 - 2004 Co-Chair, Department of Pathology Chair Search Committee, Case Western Reserve University School of Medicine
2001 - 2004 Member, Medical Resource Management Steering Committee, University Hospitals of
2001 - 2004 Chief Medical Officer, Rainbow Babies and Children's Hospital of University Hospitals of Cleveland Rainbow Babies and Children's Corporation Chair for Excellence in Pediatrics
2001 - 2004 Member, Committee on Faculty Tenure, Case Western Reserve University School of
2002 - 2003 Member, Faculty Partnering Committee, Case Western Reserve University
2002 - 2004 Member, General Clinical Research Center Advisory Committee, Case Western Reserve University School of Medicine
2002 - 2003 Member, Faculty Partnering Committee, Case Western Reserve University
2002 - 2003 Member, Department of Orthopedics Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Randall Marcus named Chairman, 2003)
2002 - 2003 Member, University Hospitals and Case Western Reserve University Affiliation Committee, University Hospitals of Cleveland
2002 - 2003 Member, Department of Orthopedics Chair Search Committee, Case Western Reserve University School of Medicine (Dr. Randall Marcus named Chairman, 2003)
2002 - 2004 Member, General Clinical Research Center Advisory Committee, Case Western Reserve University School of Medicine
2002 - 2003 Member, Blueprint for Change Committee (Rainbow Babies & Children's Hospital
2003 - 2004 Chair (Executive Sponsor), and Member, Executive Steering Committee, Children's
2003 - 2004 Member, Vice Dean for Research Advisory Committee, Case Western Reserve University School of Medicine
2003 - 2004 Member, Vice Dean for Research Advisory Committee, Case Western Reserve University
2004 - 2005 Chair, General Clinical Research Center Director, Search Committee, Medical College of Wisconsin (Dr. Theodore Kotchen named Director, 2005)
2004 - 2015 Member, Dean's Council for Research, Medical College of Wisconsin
2004 - 2008 Member, General Clinical Research Center Advisory Committee, Medical College of Wisconsin
2004 - 2005 Chair, General Clinical Research Center Director, Search Committee, Medical College of Wisconsin (Dr. Theodore Kotchen named Director, 2005)
2004 - Present Member, Dean's Council for Research, Medical College of Wisconsin
2004 - 2008 Member, General Clinical Research Center Advisory Committee, Medical College of Wisconsin
2004 - 2012 Founding Director, Children's Research Institute, Children's Hospital and Health System of Wisconsin
2005 - 2015 Member, Foundation Grants & Awards Committee, Medical College of Wisconsin
2005 - 2015 Member, Department of Pediatrics Promotions Committee, Medical College of Wisconsin
2005 - 2015 Member, Internal Referral Committee, Medical College of Wisconsin
2005 - 2015 Member, Clinical Research Scholars Selection Committee, Medical College of Wisconsin
2005 - 2015 Internal Advisory Committee for the Cardiovascular Research Center, Medical College of Wisconsin
2005 - Present Member, Internal Referral Committee, Medical College of Wisconsin
2005 - Present Internal Advisory Committee for the Cardiovascular Research Center, Medical College of
2005 - Present Bioinformatics Steering Committee, Medical College of Wisconsin
2005 - Present Member, Foundation Grants & Awards Committee, Medical College of Wisconsin
2005 - Present Member, Department of Pediatrics Promotions Committee, Medical College of Wisconsin
2005 - Present Member, Clinical Research Scholars Selection Committee, Medical College of Wisconsin
2005 - 2010 Bioinformatics Steering Committee, Medical College of Wisconsin
2005 - 2012 Board of Directors, Foundation of the Children's Hospital and Health System of Wisconsin
2005 - 2012 Member, Strategic Planning Committee, Children's Hospital and Health System Foundation
2006 - 2012 Member, Medical College of Wisconsin, Research Core Evaluation Committee
2006 - 2012 Member, Strategic Planning Research Task Force, Medical College of Wisconsin
2006 - Present Member, Strategic Planning Research Task Force, Medical College of Wisconsin
2006 - Present Member, Medical College of Wisconsin, Research Core Evaluation Committee
2007 - 2015 Associate Director, Kidney Disease Center, Medical College of Wisconsin
2007 - Present Associate Director, Kidney Disease Center, Medical College of Wisconsin
2007 - 2015 Director, Multidisciplinary Translational Center for Childhood Polycystic Kidney Disease, Children's Hospital and Health System of Wisconsin
2007 - 2012 Chair and Member, Children's Research Campaign Sub-Committee, Children's Hospital and Health System Foundation
2008 - Present Member, Pediatrics Joint Task Force, Medical College of Wisconsin
2008 - 2015 Member, Pediatrics Joint Task Force, Medical College of Wisconsin
2009 - 2012 Dean's Research leadership Council, Medical College of Wisconsin
2012 - 2015 Advisor, Children's Research Institute
University of Washington
Reserve University School of Medicine
Medicine
HOSPITAL ADMINISTRATIVE APPOINTMENTS
Research Foundation / ECG Management Consultants Project
Center, Seattle, WA
Hospitals of Cleveland
Cleveland
Service Line), University Hospitals of Cleveland
CLINICAL ADMINISTRATIVE APPOINTMENTS

HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:
1982 - 1988 Utilization Review Committee, Children's Hospital of Pittsburgh
1983 - 1988 Resident Selection Committee, Children's Hospital of Pittsburgh
1983 - 1988 Animal Research and Care Committee, Children's Hospital of Pittsburgh
1984 - 1988 Chairman, Animal Research and Care Committee, Children's Hospital of Pittsburgh
1985 - 1988 Chairman, Resident Selection Committee, Children's Hospital of Pittsburgh
1986 - 1988 Research Advisory Committee, Children's Hospital of Pittsburgh
1987 - 1988 Vice-Chairman, Research Advisory Committee, Children's Hospital of Pittsburgh
1988 - 1995 Director, Pediatrics, Division of Nephrology, Children's Hospital and Medical Center, Seattle, WA
1989 - 1995 Research Advisory Committee, Children's Hospital and Medical Center
1989 - 1995 Resident Selection Committee, Children's Hospital & Medical Center
1990 - 1995 Executive Committee on Transplantation, Children's Hospital and Medical Center
1990 - 1992 Chronic Care Task Force, Children's Hospital and Medical Center
1991 - 1994 Chairman, Animal Care and Use Committee, Children's Hospital and Medical Center
1993 - 1995 Contracts Committee, Children's University Medical Group
1993 - 1995 Chairman, Fellowship Funding Committee Children's Hospital and Medical Center
1993 - 1995 Quality Improvement/Peer Review Committee, Children's Hospital and Medical Center
1993 - 1995 Managed Care Committee, Department of Medicine, Children's Hospital and Medical
1994 - 2004 Co-Chair, Reaggregation Design Team, Children's Hospital and Medical Center
1994 - 1995 Regional Outreach Task Force, Children's Hospital and Medical Center
1995 - 1998 Member, Board of Directors, University Faculty Practice Association, University Hospitals of Cleveland
1995 - 2004 Executive Committee, Clinical Council, University Hospitals of Cleveland
1995 - 2004 Member, Clinical Leadership Advisory Committee, University Hospitals of Cleveland
1995 - 2004 University Primary Care Physicians / University Faculty Practice Association Liaison Committee, University Hospitals of Cleveland
1995 - 2004 Member, Council of Clinical Chairs, University Hospitals of Cleveland
1995 - 2004 Member, Clinical Council, University Hospitals of Cleveland
1995 - 2004 Director of Pediatrics, Rainbow Babies and Children's Hospital and University Hospitals
1996 - 2003 Member, Clinical Council Credentialing Subcommittee, University Hospitals of Cleveland
1997 - 2004 Member, Minority Faculty Development Committee, University Hospitals of Cleveland
1998 - 2003 Member, Internal Affiliation Committee, University Hospitals of Cleveland
1999 - 2004 Member, Ad Hoc Committee on Safety of Polyvinylchloride/Phthalates, University
1999 - 2003 Member, Operational Advisory Committee, University Hospital Faculty Services
1999 - 2004 Member, Mary B. Lee Endowment Fund Committee, University Hospitals of Cleveland
1999 - 2003 Policy Advisory Committee, Research Institute, University Hospitals of Cleveland
1999 - 2003 Member (Alternate), Executive Board, University Hospitals Faculty Services
1999 - 2003 Space Planning Committee, Research Institute, University Hospitals of Cleveland
2000 - 2003 Member, Executive Committee, University Hospitals Research Institute
2000 - 2003 Member, Conflict of Interest Policy Development Committee, University Hospitals Research Institute
2000 - 2004 Member, CWRU/UHC Research and Intellectual Property Task Force, University Hospitals of Cleveland
2000 - 2003 Member, Performance Indicators Advisory Committee, University Hospitals of Cleveland
2000 - 2003 Member, Quality Monitoring Council, University Hospitals of Cleveland
2000 - 2004 Chair, Educational and Research Mission Workgroup, University Hospitals of Cleveland
2001 - 2004 Chief Medical Officer, Rainbow Babies and Children's Hospital of University Hospitals of Cleveland Rainbow Babies and Children's Corporation Chair for Excellence in Pediatrics
2001 - 2004 Member, Medical Resource Management Steering Committee, University Hospitals of
2002 - 2003 Member, University Hospitals and Case Western Reserve University Affiliation Committee, University Hospitals of Cleveland
2002 - 2003 Member, Blueprint for Change Committee (Rainbow Babies & Children's Hospital
2003 - 2004 Chair (Executive Sponsor), and Member, Executive Steering Committee, Children's
2004 - Present Director, Children's Research Institute, Children's Hospital and Health System of Wisconsin
2005 - Present Member, Strategic Planning Committee, Children's Hospital and Health System Foundation
2007 - Present Director, Polycystic Kidney Disease Clinic, Children's Hospital and Health System of Wisconsin
2007 - Present Chair and Member, Children's Research Campaign Sub-Committee, Children's Hospital and Health System Foundation

RESEARCH ADMINISTRATIVE APPOINTMENTS:
1987 - Present Member, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1987 - Present Member, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1989 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1989 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1990 - Present Member, Ad-Hoc Scientific Study Section NIDDK (Diabetic Nephropathy)
1990 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1990 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1990 - Present Member, Ad-Hoc Scientific Study Section NIDDK (Diabetic Nephropathy)
1991 - Present Ad-Hoc Member, General Medicine B Study Section, NIDDK
1991 - 1995 Regular Member, General Medicine B Study Section, NIDDK
1991 - Present Ad-Hoc Member, General Medicine B Study Section, NIDDK
1991 - 1995 Regular Member, General Medicine B Study Section, NIDDK
1992 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development, Polycystic Kidney Disease)
1992 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development, Polycystic Kidney Disease)
1993 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development)
1993 - 1995 Chairman, General Medicine B Study Section, NIDDK
1993 - 1995 Chairman, General Medicine B Study Section, NIDDK
1993 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development)
1995 - 1996 Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1995 - 1999 Member, National Institutes of Health Reviewers Reserve
1995 - 1996 Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1995 - 1999 Member, National Institutes of Health Reviewers Reserve
2000 - 2001 Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
2000 - 2001 Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
2002 - Present Member, Committee on Scientific Study Section Reorganization, NIDDK
2002 - Present Member, Committee on Scientific Study Section Reorganization, NIDDK
2002 - Present Chairman, Ad-Hoc Scientific Study Section, NIAID (Cooperative Clinical Trial in Pediatric Transplantation)
2002 - Present Chairman, Ad-Hoc Scientific Study Section, NIAID (Cooperative Clinical Trial in Pediatric Transplantation)
2004 - 2015 Ad- Hoc Member, Kidney Development and Urology Study Section, NIDDK
2004 - Present Ad- Hoc Member, Kidney Development and Urology Study Section, NIDDK
2005 - Present Ad-Hoc Member, Intercellular Interactions Study Section, NIH
2005 - 2015 Ad-Hoc Member, Intercellular Interactions Study Section, NIH
2008 - Present Ad-Hoc Reviewer, National Children's Study Adjunct Studies, NICHD
2008 - 2015 Ad-Hoc Reviewer, National Children's Study Adjunct Studies, NICHD
2009 - Present Ad-Hoc Reviewer, Kidney Development and Urology Study Section, NIDDK
2009 - Present Chairman, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
NATIONAL INSTITUTES OF HEALTH PEER-REVIEW

HOSPITAL STAFF PRIVILEGES:
1980 - 1988 Staff Nephrologist, Children's Hospital of Pittsburgh, Pittsburgh, PA
1980 - 1988 Staff Nephrologist, Children's Hospital of Pittsburgh
1988 - 1995 Director, Division of Nephrology, Children's Hospital and Medical Center, Seattle, WA
1988 - 1995 Staff Nephrologist, Children's Hospital Medical Center, Seattle
1988 - 1995 Staff Nephrologist, Seattle Children's Hospital
1995 - 2004 Staff Nephrologist, Rainbow Babies and Children's Hospital
1995 - 2004 Director of Pediatrics, Rainbow Babies and Children’s Hospital and University Hospitals, Cleveland, OH
1995 - 2004 Staff Nephrologist, Rainbow Babies and Children's Hospital, Cleveland
2001 - 2004 Chief Medical Officer, Rainbow Babies and Children’s Hospital of University Hospitals, Cleveland, OH
2004 - 2015 Staff Nephrologist, Children's Hospital of Wisconsin
2004 - 2015 Staff Nephrologist, Children's Hospital of Wisconsin
2004 - 2012 Founding Director, Rainbow Babies and Children’s Hospital of University Hospitals, Children’s Research Institute, Children’s Hospital and Health System of Wisconsin, Milwaukee, WI
2004 - Present Attending Physician, Division of Nephrology, Children’s Hospital and Health System of Wisconsin
2007 - Present Director, Polycystic Kidney Disease Program, Children’s Hospital and Health System of Wisconsin, Milwaukee, WI

SPECIALTY BOARDS AND CERTIFICATION:
Certificates
Issued By Issue DateExpiration
National Board of Medical Examiners
1976
None
American Board of Pediatrics
1980
None
Sub-Board of Pediatric Nephrology, American Board of Pediatrics
1982
None
 

Licensure
Number Issue DateExpiration
State of Massachusetts Temporary Licensure
1975
1980
State of Pennsylvania Licensure
1980
1988
State of Washington Licensure
1988
1995
State of Montana Licensure
1990
None
State of Ohio Licensure
1995
2005
State of Wisconsin Licensure
2004
None
 

AWARDS AND HONORS:
1970 - Present Potts Award in Biblical Scholarship, Princeton University
1970 - Present Woodrow Wilson National Scholar
1970 - Present Potts Award in Biblical Scholarship, Princeton University
1970 - Present Magna Cum Laude, Princeton University
1970 - Present Magna Cum Laude, Princeton University
1970 - Present Woodrow Wilson National Scholar
1974 - Present Alpha Omega Alpha Honor Medical Society
1974 - Present Alpha Omega Alpha Honor Medical Society
1975 - Present Spencer Morris Prize in Medicine, University of Pennsylvania School of Medicine
1975 - Present Spencer Morris Prize in Medicine, University of Pennsylvania School of Medicine
1982 - 1985 Basil O'Connor Research Award, March of Dimes National Birth Defects Foundation
1982 - 1985 Basil O'Connor Research Award, March of Dimes National Birth Defects Foundation
1984 - 1987 New Investigator Research Award, National Institutes of Health
1984 - 1987 New Investigator Research Award, National Institutes of Health
1986 - Present Award of Tenure, University of Pittsburgh School of Medicine
1986 - 1992 Councilor, International Pediatric Nephrology Association
1986 - Present Award of Tenure, University of Pittsburgh School of Medicine
1986 - 1992 Councilor, International Pediatric Nephrology Association
1988 - 1991 Councilor, Society for Pediatric Research
1988 - 1991 Councilor, Society for Pediatric Research
1990 - Present Award of Tenure, University of Washington School of Medicine
1990 - Present Award of Tenure, University of Washington School of Medicine
1994 - Present Best Doctors in America, Woodward/White, Inc.
1994 - Present Kidney Research Aid Fund Award (Institute of Child Health, London, England)
1994 - Present Best Doctors in America, Woodward/White, Inc.
1994 - Present Kidney Research Aid Fund Award, Institute of Child Health, London, England
1995 - Present Mitchell Rubin Award in Pediatric Nephrology, Children’s Hospital of Buffalo
1995 - Present Councilor, American Society of Pediatric Nephrology
1995 - Present Award of Tenure, Case Western Reserve University School of Medicine
1995 - 1997 Councilor, American Society of Pediatric Nephrology
1995 - Present Award of Tenure, Case Western Reserve University School of Medicine
1995 - Present Mitchell Rubin Lectureship and Award for Contributions to Pediatric Nephrology
1996 - Present David Cornfeld Award in Pediatric Nephrology, Children’s Hospital of Philadelphia
1996 - Present David Cornfeld Lectureship and Award in Pediatric Nephrology (Children's Hospital
1997 - Present Dean's Distinguished Lecturer, Wayne State University School of Medicine
1997 - Present Elected Fellow, American Association for the Advancement of Science "For outstanding contributions to unraveling the mechanisms of human polycystic kidney disease"
1997 - 2000 Secretary/Treasurer, American Society of Pediatric Nephrology
1997 - Present Foreign Member, Kazakhstan Academy of Medical Sciences
1997 - 2000 Assistant Secretary, International Pediatric Nephrology Association
1997 - Present Dean's Distinguished Lecturer, Wayne State University School of Medicine
1997 - 2000 Assistant Secretary, International Pediatric Nephrology Association
1997 - Present Foreign Member, Kazakhstan Academy of Medical Sciences
1997 - 2000 Secretary/Treasurer, American Society of Pediatric Nephrology
1997 - Present Elected Fellow, American Association for the Advancement of Science "For outstanding contributions to unraveling the mechanisms of human polycystic kidney disease"
2000 - 2002 President-Elect, American Society of Pediatric Nephrology
2000 - 2002 President-Elect, American Society of Pediatric Nephrology
2001 - 2012 America's Top Doctors, Castle Connolly Medical Ltd.
2001 - Present Distinguished Service Award in Health Care Education, Royal National Lao University, Lao PDR
2001 - 2007 Member, Standing Committee, International Pediatric Association
2001 - 2002 America's Top Doctors, Castle Connolly Medical Ltd.
2001 - 2007 Member, Standing Committee, International Pediatric Association
2001 - Present Distinguished Service Award in Health Care Education, Royal National Lao University, Lao PDR
2001 - 2003 Million Dollar Professor, Case Western Reserve University
2001 - 2010 Councilor, International Pediatric Nephrology Association
2001 - 2003 Million Dollar Professor, Case Western Reserve University
2001 - Present Councilor, International Pediatric Nephrology Association
2001 - 2007 Standing Committee, International Pediatric Association
2001 - Present Jean Pouliot Award and Lectureship in Pediatric Research, Montreal, Canada
2001 - Present The Jean Pouliot Award and Lectureship in Pediatric Research, Montreal, Canada
2002 - 2004 President, American Society of Pediatric Nephrology
2002 - Present March of Dimes Distinguished Lecturer, New York Academy of Medicine
2002 - 2004 Rainbow Babies Corporation, Chair for Excellence in Pediatrics
2002 - Present Juvenile Diabetes Foundation Award , Research Achievement
2002 - Present Juvenile Diabetes Foundation Award for Research Achievement
2002 - 2004 President, American Society of Pediatric Nephrology
2002 - Present March of Dimes Distinguished Lecturer, New York Academy of Medicine
2003 - Present Howard Mermelstein Memorial Lecture, Children's Hospital of Pittsburgh
2003 - 2004 Honored Member, Lifetime Achievement Award, Strathmore' Who's Who
2003 - 2004 Honored Member, Lifetime Achievement Award, Strathmore’s Who’s Who
2003 - 2004 President, Council of American Kidney Societies
2003 - Present Howard Mermelstein Memorial Lecture, Children's Hospital of Pittsburgh
2003 - 2004 President, Council of American Kidney Societies
2003 - 2004 Honored Member, Lifetime Achievement Award, Strathmore' Who's Who
2004 - 2007 Member, Executive Committee, International Pediatric Association
2004 - Present Award of Tenure, Medical College of Wisconsin
2004 - 2007 Member, Executive Committee, International Pediatric Association
2004 - Present Award of Tenure, Medical College of Wisconsin
2008 Invited IPNA Plenary Lecture, ESPN Annual Meeting, Lyon, France
2008 - Present Henry L. Barnett Award for Excellence in Clinical Care and Education in Pediatric Nephrology, American Academy of Pediatrics
2008 - Present Invited IPNA Plenary Lecture, ESPN Annual Meeting, Lyon, France
2008 - Present Henry L. Barnett Lifetime Achievement Award, American Academy of Pediatric
2009 - Present America’s Top Doctors Award, Castle Connolly Medical Ltd.
2010 - Present Outstanding MCW Medical Student Teaching Award, Physiology
2010 - Present Outstanding Medical Student Teaching Award, Medical College of Wisconsin (Physiology)
2012 “America’s Top Pediatricians”, Consumers Research Council of America
2012 “ Leading Nephrologists in WI”, The International Association of Healthcare Professionals
2013 “Leading Physicians in the World” , The International Association of Healthcare Professionals
2013 - Present Named "Leading Physicians in the World", IAHCP
2014 - Present Invited Presidential Plenary Speaker, Pediatric Academic Societies Annual Meeting
2014 - Present Invited Presidential Plenary Speaker, Pediatric Academic Societies Annual Meeting
2014 - Present Inaugural Invited Speaker, Demetrius Ellis M.D. Annual Lecture in Pediatric Nephrology, Children's Hospital of Pittsburgh
2014 - Present Inaugural Speaker, "Demetrius Ellis M.D. Annual Lecture in Pediatric Nephrology" Children's Hospital of Pittsburgh
2014 Invited Plenary Speaker, Pediatric Academic Societies Annual Meeting
2016 - Present Founders' Award for Lifetime Achievements in Pediatric Nephrology, American Society of Pediatric Nephrology
2016 - Present Educational Excellence Award for Lifetime Global Achievements as an Educator, International Society of Pediatric Nephrology

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
1980 - Present American Society of Pediatric Nephrology (Member)
1980 - Present American Society of Nephrology
1980 - Present American Society of Pediatric Nephrology
1980 - Present American Society of Nephrology (Member)
1980 - Present Society for In Vitro Biology
1980 - Present Society for In Vitro Biology (Member)
1981 - Present International Society of Nephrology
1981 - Present International Society of Nephrology (Member)
1981 - Present International Pediatric Nephrology Association (Member)
1981 - Present International Pediatric Nephrology Association
1982 - Present American Society of Transplant Physicians (Member)
1982 - Present American Society of Transplant Physicians
1983 - Present American Federation for Clinical Research (Member)
1983 - Present American Federation for Clinical Research
1983 - Present American Journal of Diseases of Children
1984 - 1988 Midwest Society for Pediatric Research
1984 - Present In Vitro Cellular and Developmental Biology
1984 - 1988 Midwest Society for Pediatric Research (Member)
1985 - Present Society for Pediatric Research (elected)
1985 - Present Society for Pediatric Research (elected)
1986 - Present Sigma Xi - Scientific Research Society of North America (elected)
1986 - Present Journal of Clinical Investigation
1986 - Present Pediatric Nephrology
1986 - Present American Society for Cell Biology (Member)
1986 - Present Sigma Xi - Scientific Research Society of North America (elected)
1986 - 1988 Pittsburgh Pediatric Society (Member)
1986 - 1988 Pittsburgh Pediatric Society
1986 - Present American Society for Cell Biology
1987 - Present Pediatric Research
1988 - 1989 Western Society for Pediatric Research (Member)
1988 - Present American Journal of Medical Genetics
1988 - Present Kidney International
1989 - Present Fellow (American Academy of Pediatrics)
1989 - 1995 Washington State Medical Association
1989 - 1995 King County Medical Society
1989 - 1995 North Pacific Pediatric Society
1989 - 1995 Northwest Renal Society
1989 - Present Western Society for Pediatric Research
1989 - Present American Academy of Pediatrics (Fellow)
1989 - 1995 Washington State Medical Association (m)
1989 - 1995 Northwest Renal Society (Member)
1989 - 1995 King County Medical Society (Member)
1989 - 1994 Western Society for Pediatric Research
1989 - 1995 North Pacific Pediatric Society (Member)
1990 - 1995 Northwest Transplantation Society (Member)
1990 - 1995 Northwest Transplantation Society
1990 - Present Growth, Development (and Aging)
1990 - Present Journal American Society of Nephrology
1991 - Present American Journal of Physiology
1992 - Present New England Journal of Medicine
1992 - 2008 Kidney International
1993 - Present American Pediatric Society (elected)
1993 - Present American Pediatric Society (elected)
1993 - Present American Journal of Kidney Diseases
1993 - Present Scanning Electron Microscopy
1993 - 2004 Seminars in Nephrology
1993 - 1997 Pediatric Nephrology
1994 - Present Pediatric Pathology
1994 - 1996 Transplant Chronicles
1995 - Present American Journal of Pathology
1995 - 2004 Northern Ohio Pediatric Society
1995 - 2004 Association of Medical School Pediatric Department (Chairman)
1995 - 2004 Association of Medical School Pediatric Department Chairman
1995 - 2004 Northern Ohio Pediatric Society (Member)
1995 - 1999 American Journal of Kidney Diseases
1996 - Present Journal of Urology
1996 - Present Human Molecular Genetics
1996 - Present Journal of Pediatrics
1997 - 2004 Assistant Editor (Basic Science) (Pediatric Nephrology)
1997 - Present Pediatrics
2000 - 2008 Cooperating Editor (Kidney and Homeostasis) (Cell and Tissue Research)
2001 - Present American Journal of Transplantation
2001 - 2005 Renal Physicians Association
2001 - 2005 Renal Physicians Association (Member)
2004 - 2009 Pediatric Nephrology
2004 - 2010 Current Pediatric Reviews
2004 - 2013 Pediatric Research Leaders Association (SPR and APS (elected))
2004 - 2012 Current Reviews in Pediatrics
2005 - Present Asian Journal of Pediatric Practice
2005 - 2011 Journal of the American Society of Nephrology
2009 - Present Journal of Pediatric Sciences
2010 - Present Adolescent Health (Medicine and Therapeutics)
2014 - Present Nature Reviews in Nephrology
2014 - Present Trends in Molecular Medicine
EDITORSHIPS/EDITORIAL BOARDS/REVIEW
Journal Reviewer

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Editorial Board
1992 - 2008 Kidney International
1993 - 1997 Pediatric Nephrology
1993 - 2004 Seminars in Nephrology
1994 - 1996 Transplant Chronicles
1995 - 1999 American Journal of Kidney Diseases
1997 - 2004 Assistant Editor (Basic Science), Pediatric Nephrology
2000 - 2008 Cooperating Editor (Kidney and Homeostasis), Cell and Tissue Research
2004 - Present Pediatric Nephrology
2004 - Present Current Reviews in Pediatrics
2004 - 2012 Journal of the American Society of Nephrology
2004 - Present Current Pediatric Reviews
2005 - Present 2005- Journal of the American Society of Nephrology
2005 - Present Asian Journal of Pediatric Practice
2009 - Present Journal of Pediatric Sciences
2010 - Present Adolescent Health, Medicine and Therapeutics
Journal Review
1983 - Present American Journal of Diseases of Children
1984 - Present In Vitro Cellular and Developmental Biology
1986 - Present Pediatric Nephrology
1986 - Present Journal of Clinical Investigation
1987 - Present Pediatric Research
1988 - Present American Journal of Medical Genetics
1988 - Present Kidney International
1990 - Present Growth, Development, and Aging
1990 - Present Journal American Society of Nephrology
1991 - Present American Journal of Physiology
1992 - Present New England Journal of Medicine
1993 - Present American Journal of Kidney Diseases
1993 - Present Scanning Electron Microscopy
1994 - Present Pediatric Pathology
1995 - Present American Journal of Pathology
1996 - Present Journal of Urology
1996 - Present Human Molecular Genetics
1996 - Present Journal of Pediatrics
1997 - Present Pediatrics
2001 - Present American Journal of Transplantation

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
1980 - 1988 Member, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania
1980 - 1988 Medical Advisory Board, National Kidney Foundation of Western Pennsylvania
1980 - 1988 Medical Advisory Board, National Kidney Foundation of Western Pennsylvania
1980 - 1988 Medical Advisory Board, National Kidney Foundation of Western Pennsylvania
1983 - 1988 Secretary, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania
1983 - 1988 Secretary, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania
1983 - 1988 Secretary, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania
1983 - 1988 Secretary, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania
1984 - 1988 Chair, Animal Research and Care Committee, Children’s Hospital of Pittsburgh
1985 - 1988 Chair, Resident Selection Committee, Children's Hospital of Pittsburgh
1986 - 1988 Member, Research Advisory Committee, Children's Hospital of Pittsburgh
1987 - 1988 Vice-Chair, Research Advisory Committee, Children's Hospital of Pittsburgh
1989 - 1995 Medical Advisory Board, Northwest Kidney Foundation
1989 - 1995 Medical Advisory Board, Northwest Kidney Foundation
1989 - 1995 Member, Resident Selection Committee, Children's Hospital & Medical Center, Seattle
1989 - 1995 Member, Medical Advisory Board, Northwest Kidney Foundation
1989 - 1995 Member, Research Advisory Committee, Children's Hospital and Medical Center, Seattle
1989 - 1995 Medical Advisory Board, Northwest Kidney Foundation
1990 - 1992 Member, Chronic Care Task Force, Children's Hospital and Medical Center, Seattle
1990 - 1995 Board Member, Northwest Organ Procurement Agency
1990 - 1995 Board Member, Northwest Organ Procurement Agency
1990 - 1995 Board Member, Northwest Organ Procurement Agency
1990 - 1995 Member, Executive Committee on Transplantation, Children's Hospital and Medical Center, Seattle
1992 - 1995 Medical Advisory Board, Starlight Foundation of Western Washington
1992 - 1995 Medical Advisory Board, Starlight Foundation of Western Washington
1992 - 1995 Medical Advisory Board, Starlight Foundation of Western Washington
2001 - 2004 Member, Committee on Faculty Tenure, Case Western Reserve University School of Medicine
2001 - 2003 Board Member, University Genetics, Inc.
2001 - 2004 Member, Executive Committee, Rainbow Circle of Friends, Rainbow Babies & Children's
2001 - 2004 Co-Chair, Department of Pathology Chair Search Committee, Case Western Reserve University School of Medicine
2001 - 2004 Member, Executive Committee, Rainbow Circle of Friends, Rainbow Babies & Children's
2001 - 2003 Board Member, University Genetics, Inc.
2001 - 2004 Member, Executive Committee, Rainbow Circle of Friends, Rainbow Babies & Children's
2001 - 2003 Board Member, University Genetics, Inc.
2002 - 2003 Member, Case Western Reserve University School of Medicine Chair Search Committee, Department of Orthopedics
2002 - 2004 Member, Subcommittee for Rainbow Babies & Children's Hospital, University Hospitals
2002 - 2004 Member, General Clinical Research Center Advisory Committee, Case Western Reserve University School of Medicine
2002 - 2004 Member, Subcommittee for Rainbow Babies & Children's Hospital, University Hospitals
2002 - 2003 Member, Faculty Partnering Committee, Case Western Reserve University
2002 - 2004 Member, Subcommittee for Rainbow Babies & Children's Hospital, University Hospitals
2003 - Present Member, Board of Directors, Kidney and Urology Foundation of America
2003 - 2004 Member, Research Advisory Committee, Case Western Reserve University School of Medicine
2003 - Present Member, Board of Directors, Kidney and Urology Foundation of America
2003 - 2007 Member, Board of Directors, International Pediatric Association Corporation
2003 - Present Member, Board of Directors, Kidney and Urology Foundation of America
2003 - 2007 Member, Board of Directors, International Pediatric Association Corporation
2003 - 2007 Member, Board of Directors, International Pediatric Association Corporation
2004 - 2005 Chair, General Clinical Research Center Director, Search Committee, Medical College of Wisconsin
2004 Member, Dean’s Council for Research, Medical College of Wisconsin
2004 - 2008 Member, General Clinical Research Center Advisory Committee, Medical College of Wisconsin
2005 Member, Bioinformatics Steering Committee, Medical College of Wisconsin
2005 Member, Internal Advisory Committee for the Cardiovascular Research Center, Medical College of Wisconsin
2005 Member, Foundation Grants & Awards Committee, Medical College of Wisconsin
2005 Associate Director, Kidney Disease Center, Medical College of Wisconsin
2005 Member, Department of Pediatrics Promotions Committee, Medical College of Wisconsin
2005 Member, Clinical Research Scholars Selection Committee, Medical College of Wisconsin
2005 - Present Member, Board of Directors, Foundation of the Children's Hospital and Health System of Wisconsin
2005 - Present Member, Board of Directors, Foundation of the Children's Hospital and Health System of Wisconsin
2005 - Present Member, Board of Directors, Foundation of the Children's Hospital and Health System of Wisconsin
2006 Member, Strategic Planning Research Task Force, Medical College of Wisconsin
2006 Member, Research Core Evaluation Committee, Medical College of Wisconsin
2007 Associate Director, Kidney Disease Center, Medical College of Wisconsin
2008 Member, Planning Committee, Foundation of the Children’s Hospital and Health System of Wisconsin
2008 Member, Pediatrics Joint Task Force, Medical College of Wisconsin
2009 - Present Member, Cardiovascular Center Scientific Advisory Committee, Medical College of Wisconsin
2009 - 2011 Member and Program Lecturer, Summer Program Undergraduate Research Committee, Medical College of Wisconsin
2009 Member, Dean’s Research Leadership Council, Medical College of Wisconsin
2009 - 2011 Member and Program Lecturer, Summer Program Undergraduate Research Committee, Medical College of Wisconsin
2010 Elected, National Representative, Clinical Translational Science Award (CTSA) Child Health Oversight Committee, Medical College of Wisconsin
2010 - 2013 Member, Cardiovascular Center Scientific Advisory Committee, Medical College of Wisconsin
2011 Member, Search Committee, Department of OB/GYN
Hospital Board of Trustees
of Cleveland Board of Trustees
of Cleveland Board of Trustees
Hospital Board of Trustees
Hospital Board of Trustees
of Cleveland Board of Trustees

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
1980 - 1988 Member, Medical Advisory Board, National Kidney Foundation of Western Pennsylvania
1985 - 1995 Member, Medical Advisory Board, Northwest Kidney Foundation
1985 - 1988 Member, Scientific Program Committee, Midwest Society for Pediatric Research Annual Meeting
1987 Member, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1987 Member, Committee on Transplantation, American Society of Pediatric Nephrology
1987 Member, International Scientific Program Committee, Eighth Congress of the International Pediatric Nephrology Association
1988 Member, International Advisory Committee, Fourth International Workshop on Developmental Renal Physiology
1989 Invited Participant, Somatic Cell and Molecular Genetics Workshop, Eleanor Roosevelt Institute for Cancer Research and the National Cancer Institute
1989 Chair, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1989 Member, Scientific Grant Proposal Review, March of Dimes Birth Defects Foundation
1990 - 1995 Member, Advisory Committee on Organ Procurement, Pacific Northwest Organ Society
1990 Member, Scientific Grant Proposal Review, Veteran's Health Services and Research Administration
1990 - 1995 Consultant, Scientific Review, Medical Research Council of Canada (Polycystic Kidney Disease, Renal Growth Factors)
1990 Scientific Advisor, Office for Research, University of Melbourne, Australia (Polycystic Kidney Disease)
1990 Member, Ad-Hoc Scientific Study Section, NIDDK (Diabetic Nephropathy)
1990 - 1995 Member, Board of Trustees, Northwest Organ Procurement Agency
1990 Chair, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1991 Ad-Hoc Member, General Medicine B Study Section, NIDDK
1991 - 1999 Member, Board of Scientific Advisors, Polycystic Kidney Research Foundation
1991 - 1992 Member, Ad-Hoc Pediatric Committee, UNOS
1991 - 1995 Member, General Medicine B Study Section, NIDDK
1991 Member, International Organizing Committee, Fifth International Workshop on Developmental Renal Physiology
1991 Member, NIH Planning Committee, Research and Training in Pediatric Nephrology
1991 - 2000 Member, Research Committee, American Society of Pediatric Nephrology
1992 Chair, Society for Pediatric Research Annual Meeting, Scientific Program (Nephrology)
1992 - 1995 Member, Medical Advisory Board, Starlight Foundation of Western Washington
1992 - 1997 Scientific Advisor, University of Colorado Center for the Study of Polycystic Kidney Disease
1992 Scientific Advisor, Washington University Nephrology Center - Kidney Development
1992 Chair, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development, Polycystic Kidney Disease)
1992 - 1996 Member, Scientific Advisory Committee, North American Pediatric Renal Transplant Cooperative Study
1992 Member, NIH Strategic Planning Committee (Pediatric Nephrology)
1993 - 1999 Member, Pediatric Committee, American Society of Transplant Physicians
1993 - 1999 Chair, Scientific Committee, International Study of Genetic Renal Diseases
1993 - 1999 Member, Executive Committee, International Study of Genetic Renal Diseases
1993 - 1999 Member, Scientific Advisory Committee, International Pediatric Nephrology Association
1993 Member, Program Committee, Society for Pediatric Research Annual Meeting
1993 Co-Chair, Program Committee, American Society of Nephrology Annual Meeting
1993 Chair, Ad-Hoc Scientific Study Section, NIDDK (Kidney Development)
1993 - 1995 Chair, General Medicine B Study Section, NIDDK
1994 - 1995 Member, Organizing Committee, 6th International Workshop on Developmental Nephrology
1994 - 1995 Member, Scientific Program Committee, 10th Congress of the International Pediatric Nephrology Association
1994 - 1995 Co-Chair, Pediatric Committee, American Society of Transplant Physicians
1994 Scientific Reviewer, Wellcome Trust Grant Program (Molecular and Cell Biology)
1995 - 1999 Member, National Institutes of Health Reviewers Reserve
1995 Co-Chair, American Society of Nephrology Annual Meeting, Symposium on Renal Development/Differentiation
1995 - 1998 Member, Peters and Scribner Awards Subcommittees, American Society of Nephrology
1995 Member, Scientific Advisory Committee, Biomedical Research Cleveland
1995 - 1996 Chair, Pediatric Committee, American Society of Transplant Physicians
1995 Co-Chair, 10th Congress of the International Pediatric Nephrology Association, Symposium on Polycystic Kidney Disease
1995 - 1996 Chair, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
1996 Chair, 1996 Basic Science Conference: Renal Developmental Biology, American Society of Nephrology
1996 Co-Chair, Symposium on Disease Progression in Pediatric Chronic Renal Insufficiency, American Society of Pediatric Nephrology Annual Meeting
1996 Member, Scientific Advisory Board, Center for Pediatric Research, Eastern Virginia Medical School
1996 Member, Nominating Committee, American Society of Nephrology
1997 Co-Chair, Symposium on Molecular Genetics and Renal Diseases, American Society of Pediatric Nephrology Annual Meeting
1997 - 2005 Member, External Advisory Committee, Pediatric Nephrology Training Grant (T32-DK07662), University of Washington
1997 - 1998 Member, Scientific Organizing Committee, 7th International Workshop on Developmental Nephrology
1997 Moderator, , Free Communications Session on Recent Advances in Polycystic Kidney Disease, American Society of Pediatric Nephrology Annual Meeting
1997 Chair, Task Force on Housestaff Recruitment, American Medical School Pediatric Department
1997 - 1998 Member, Scientific Program Committee, 11th Congress of International Pediatric Nephrology Association
1998 - 2001 Co-Chair, Scientific Program Committee, 12th Congress of International Pediatric Nephrology Association
1998 - 2001 Member, National Organizing Committee, 12th Congress of International Pediatric Nephrology Association
1998 Member, Strategic Planning Committee, NIH-Polycystic Kidney Disease Ad Hoc Advisory Committee
1998 Member, Scientific Review Committee (Polycystic Kidney Disease), American Society of Nephrology Annual Meeting
1998 Co-Chair, NIH-American Society of Nephrology Strategic Planning Committee, Renal Research Priorities: Growth, Development, Angiogenesis and Neoplasia
1999 Member, NIH-American Society of Pediatric Nephrology Strategic Planning Committee, Research Priorities
1999 - 2001 Member, Organizing Committee, 8th Annual International Workshop on Developmental Nephrology
1999 Member, Executive Committee, NIH-American Society of Nephrology Strategic Planning Committee on Renal Research Priorities
2000 - 2001 Chair, Ad-Hoc Scientific Study Section, NIDDK (Polycystic Kidney Disease)
2000 - 2004 Member, Program Planning Committee, Pediatric Academic Societies
2000 - 2004 Member, Council of American Kidney Societies
2001 - 2004 Member, Scientific Program Committee, The Thirteenth Congress of the International Pediatric Nephrology Association
2001 - 2004 Board of Trustees, Executive Committee, Rainbow Circle of Friends, Rainbow Babies & Children’s Hospital
2001 Co-Chair, Molecular Control of Renal Disease, 8th International Workshop: Developmental Nephrology, Victoria, British Columbia
2001 Co-Chair, Polycystic Renal Disease in Pediatrics, 12th International Congress of Pediatric Nephrology, Seattle, Washington
2001 - 2003 Member, Board of Trustees, University Genetics, Inc.
2002 Session Chair, FASEB Conference: Molecular Mechanisms and Therapeutic Insights into PKD. Tucson, Arizona, ARPKD: Molecular Mechanisms in Pathogenesis of ARPKD
2002 Member, External Scientific Advisory Committee, NIH Pediatric Scientist Training Program, Department of Pediatrics, Indiana University
2002 Member, Senior Scholars Committee, American Pediatric Society
2002 Co-Moderator, American Society of Pediatric Nephrology Annual Meeting, Baltimore, Maryland, Symposium on Cancer, Blood and the Kidney: Common Themes
2002 - 2004 Board of Trustees, Subcommittee for Rainbow Babies & Children’s Hospital, University Hospitals of Cleveland, Rainbow Babies & Children’s Hospital
2002 Member, Committee on Scientific Study Section Reorganization, NIDDK
2002 Chair, Ad-Hoc Scientific Study Section, NIAID (Cooperative Clinical Trial in Pediatric Transplantation)
2002 Co-Moderator, American Society of Nephrology Annual Meeting, Philadelphia, Pennsylvania, Symposium on PKD: New Genes and Mechanisms
2002 Co-Moderator, American Society of Pediatric Nephrology Annual Meeting, Baltimore, Maryland, Symposium on Molecular Basis of Renal Development and Disease
2003 Member, Nominating Committee, North American Pediatric Renal Transplant Cooperative Study
2003 - 2004 Member, Nominating Committee, American Society of Nephrology
2003 President, Council of American Kidney Societies
2003 Co-Chair, Plenary Symposium, Pediatric Solid Organ Transplantation in the 21st Century, Pediatric Academic Societies Annual Meeting, Seattle, Washington
2003 - 2004 Member, Scientific Program Committee, American Society of Nephrology, 2004 Annual Meeting
2003 - 2007 Member, Board of Directors, International Pediatric Association Corporation
2003 Member, Board of Directors, Kidney and Urology Foundation of America
2004 - 2007 Member, Scientific Program Committee, 14th Congress of the International Pediatric Nephrology Association
2004 Chair, Basic Science Symposium, Non-mammalian Models of Renal Development/Disease, American Society of Nephrology, 2004 Annual Meeting
2004 Ad- Hoc Member, Kidney Development and Urology Study Section, NIDDK
2004 - 2007 Member, Scientific Program Committee, 25th International Congress of the International Pediatric Association, Athens, Greece
2004 Chair, Plenary Symposium, Common Urinary Tract Problems in Children, The 24th Congress of the International Pediatric Association
2005 - 2010 Member, Nominations Committee, American Society of Pediatric Nephrology
2005 Board of Directors, Foundation of the Children’s Hospital and Health System of Wisconsin
2005 - 2007 Member, Finance and Development Committee, International Pediatric Association
2005 - 2007 Member, 2005-2007 Awards, Research and Development Committee, American Society of Pediatric Nephrology
2005 Ad-Hoc Member, Intercellular Interactions Study Section, NIH
2005 - 2012 Member, Board of Directors, Foundation of the Children’s Hospital and Health System of Wisconsin
2007 Chair, Scientific Advisory Board, Calesta Pharmaceuticals
2007 - 2010 Member, Scientific Program Committee, 15th Congress of the International Pediatric Nephrology Association
2007 - 2012 Member, External Scientific Advisory Committee, University of Texas Southwestern O’Brien Kidney Center
2007 Moderator, Plenary Symposium: New Approaches to UTI-VUR, 25th International Congress of Pediatrics, Athens, Greece
2007 Moderator, IPNA Symposium: Update on Common Childhood Kidney Problems, 25th International Congress of Pediatrics, Athens, Greece
2008 Co-Director, 2nd Gerry Schwartz and Heather Reisman International Congress on Children with Chronic Diseases
2008 Elected Member, Adjunct Studies Review Committee, National Children’s Study, NICHD
2008 Ad-Hoc Reviewer, National Children’s Study Adjunct Studies, NICHD
2009 Ad-Hoc Reviewer, Kidney Development and Urology Study Section, NIDDK
2009 Member, Professional Advisory Board, ARPKD/CHF Alliance
2009 - Present Member, Board of Directors, Autosomal Recessive Polycystic Kidney Disease- Congenital Hepatic Fibrosis Alliance
2009 - Present Member, Student/Laboratory Selection Committee and Program Lecturer, Summer Program Undergraduate Research Committee, Medical College of Wisconsin
2009 Chair, Ad-Hoc Study Section, Polycystic Kidney Disease, NIH
2009 - Present Member, Cardiovascular Center Scientific Advisory Committee, Medical College of Wisconsin
2012 Member, International Organizing Committee, 3rd International Conference on Pediatric Chronic Diseases, Disability and Human Development, Jerusalem, Israel
2013 Scientific Advisor and Reviewer, Goldman Family Trust for PKD Research
2013 Consultant, Human ADPKD Clinical Trials, Kadmon Pharmaceticals (SRA executed through MCW Grants and Contracts)
2013 Member, Internal Advisory Committee, Children’s Environmental Health Center, NIEHS-ES004184-26 (P.I.: David Petering, University of Wisconsin, Milwaukee)
2013 Consultant, Clinical Trials ARPKD, NIH- NHGRI (National Human Genome Research Institute)
2013 Member, Infrastructure Task Force, American Society of Pediatric Nephrology
2014 Invited Moderator, “Extra-renal manifestations, confounding factors, and biomarkers in PKD” FASEB PKD Meeting,Italy

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
Southeastern Wisconsin Clinical and Translational Science Award
Source:
National Institutes of Health (UL1RR031973)
Role:
Co-Principal Investigator
PI:
Reza Shaker, M.D.
Dates:
2010 - 2015
 
Title:
Polycystic Kidney Disease Research
Source:
Ellsworth Family Fund, Children’s Hospital Foundation
Role:
Principal Investigator
PI:
Self
Dates:
2011 - 2016
 
Title:
Children’s Environmental Health Center
Source:
NIEHS (ES-004184-24)
Role:
Director, Career Development
PI:
D .Petering, PhD
Dates:
2012 - 2014
 
Title:
Phase I-IIa Clinical Trial of KD-019 in ADPKD
Source:
Kadmon Pharmaceuticals
Role:
Primary Consultant
Dates:
2012 - 2015
 
Title:
Preliminary Studies: 20-HETE inhibition in human and murine PKD
Source:
Taisho Pharmaceuticals
Role:
Principal Investigator
PI:
Self
Dates:
2018 - 2020
 
Title:
new Therapies for the Treatment of ADPKD
Source:
Amy P. Goldman Foundation
Role:
Principal Investigator
PI:
Self
Dates:
2018 - 2021
 
Pending
Peer Review
Title:
Pre-Clinical Studies: Efficacy of 20-HETE inhibition in PKD
Source:
Taisho Pharmaceuticals
Role:
Principal Investigator
PI:
Self
Dates:
2014 - 2016
 
Title:
Phase I-IIa Clinical Study of multikinase inihibition in ARPKD
Source:
Kadmon Pharmaceuticals; NIDDK/NIH
Role:
Principal Investigator
PI:
Self
Dates:
2014 - 2018
 
Title:
Children’s Environmental Health Center
Source:
National Institutes of Environmental Health Safety (ES-004184-26)
Role:
Director, Career Development
PI:
D. Petering, PhD
Dates:
2014 - 2019
 
Prior
Peer Review
Title:
Renal Basement Membrane Formation
Source:
National Kidney Foundation of Western Pennsylvania
Role:
Principal Investigator
PI:
Self
Dates:
1981 - 1982
 
Title:
Organ Culture Studies of Renal Development
Source:
March of Dimes Birth Defects Foundation Basil O'Connor Starter Research Grant #2-857
Role:
Principal Investigator
PI:
Self
Dates:
1982 - 1985
 
Title:
Microdissection Studies in Murine Congenital Polycystic Kidney Disease
Source:
National Institutes of Health Biomedical Research Support Grant #SO7-RR0550723
Role:
Principal Investigator
PI:
Self
Dates:
1984 - 1986
 
Title:
Pathophysiology of Cyst Formation in Metanephric Organ Culture
Source:
National Institutes of Health (NIDDK), New Investigator Research Award R23-AM34891
Role:
Principal Investigator
PI:
Self
Dates:
1984 - 1987
 
Title:
Organ Culture Studies of Cystic Nephrogenesis in Congenital Murine Polycystic Disease
Source:
March of Dimes Birth Defects Foundation Basic Science Research Grant #1-954
Role:
Principal Investigator
PI:
Self
Dates:
1985 - 1987
 
Title:
Pathogenesis of Congenital Murine Cystic Nephrogenesis
Source:
National Institutes of Health (NIDDK), RO1-DK34891
Role:
Principal Investigator
PI:
Self
Dates:
1987 - 1992
 
Title:
Safety and Efficacy of Somatropin to Improve Short Stature in Chronic Renal Insufficiency (P.I. - Sandra L. Watkins, M.D.)
Source:
Genentech, Inc.
Role:
Co-Investigator
Dates:
1988 - 1991
 
Title:
Cellular Biology of Congenital Murine Cystogenesis
Source:
National Institutes of Health (NIDDK) RO1-DK44875
Role:
Principal Investigator
PI:
Self
Dates:
1991 - 1995
 
Title:
Pediatric Nephrology Molecular Biology-Cell Biology Training Grant
Source:
National Institutes of Health (NIDDK) T32-DK07662
Role:
Principal Investigator
PI:
Self
Dates:
1991 - 1996
 
Title:
Minority Faculty Development Award (Stephanie Orellana, Ph.D.)
Source:
National Institutes of Health DK44875-S1
Role:
Principal Investigator/Sponsor
PI:
Self
Dates:
1992 - 1995
 
Title:
Fellowship Trainee Award (Judith Pugh, M.D.)
Source:
National Kidney Foundation
Role:
Principal Investigator/Sponsor
PI:
Self
Dates:
1992 - 1993
 
Title:
Small Instrumentation Grant
Source:
National Institutes of Health (NIAID) AI3363
Role:
Principal Investigator
PI:
Self
Dates:
1992 - 1993
 
Title:
Physical Aspects of Cavitation in ESWL (P.I. - Ronald A. Roy, Ph.D.).
Source:
National Institutes of Health DK-43881
Role:
Co-Investigator
Dates:
1994 - 1996
 
Title:
Controlled Trial of Induction Therapy in Renal Transplantation
Source:
National Institutes of Health AI-37206
Role:
Center Principal Investigator
Dates:
1994 - 1996
 
Title:
Medical Teratology Training Program (P.I. - Philip E. Mirkes, Ph.D.)
Source:
National Institutes of Health HD-07456
Role:
Co-Investigator/Training Program Faculty
Dates:
1994 - 1996
 
Title:
Clinical Research Training in Renal Disease (P.I. – D. J. Sherrard, M.D.)
Source:
National Institutes of Health T32 DK-07721
Role:
Co-Investigator/Training Program Faculty
Dates:
1994 - 1996
 
Title:
Renal Developmental Biology Program
Source:
University Hospitals of Cleveland
Role:
Principal Investigator
PI:
Self
Dates:
1995 - 2000
 
Title:
Genetics in Training Grant (P.I. - Huntington Willard, Ph.D.)
Source:
National Institute of General Medical Sciences GM08613
Role:
Research Mentor
Dates:
1996 - 2001
 
Title:
Tyrosine Kinase Inhibition in Murine PKD
Source:
Wyeth-Ayerst Research
Role:
Principal Investigator
PI:
Self
Dates:
1996 - 1999
 
Title:
Conference on Renal Developmental Biology
Source:
National Institutes of Health DK-52001
Role:
Principal Investigator
PI:
Self
Dates:
1996 - 1997
 
Title:
Molecular Genetics of PKD in the Unique TGN737RPW Model
Source:
National Institutes of Health DK-51068
Role:
Co-Investigator
PI:
Richard P. Woychik, Ph.D
Dates:
1997 - 2000
 
Title:
Developmental Biology Training Grant (P.I. - Terry Magnuson, Ph.D.)Mentor
Source:
National Institute of Child Health and Human Development HD07104
Role:
Research Mentor
Dates:
1997 - 2001
 
Title:
Innovative Therapies in Murine Polycystic Kidney Disease
Source:
PKR Foundation 97002
Role:
Principal Investigator
PI:
Self
Dates:
1998 - 2000
 
Title:
The Center for Children’s Chronic Conditions
Source:
The Cleveland Foundation 97-0590
Role:
Principal Investigator
PI:
Self
Dates:
1998 - 2002
 
Title:
CWRU Nephrology Training Program
Source:
National Institutes of Health DK07470
Role:
Co- Principal Investigator
Dates:
1998 - 2004
 
Title:
Clinical Studies of Pediatric HUS
Source:
International Society of Nephrology
Role:
Research Mentor
Dates:
1999 - 2000
 
Title:
Interdisciplinary Center for Polycystic Kidney Disease Research
Source:
National Institutes of Health (1-P50-DK57306)
Role:
Principal Investigator
PI:
Self
Dates:
1999 - 2006
 
Title:
Project 3 of Center Grant: Pharmacological and Genetic Therapy of ARPKD
Source:
National institutes of Health (Overall Center P.I. – Ellis D. Avner, M.D.)
Role:
Principal Investigator
PI:
Self
Dates:
1999 - 2006
 
Title:
Core A of Center Grant: Administrative and Educational Core
Source:
National Institutes of Health
PI:
Ellis D. Avner, M.D
Dates:
1999 - 2006
 
Title:
Innovative Therapies for PKD: Pre-Clinical Studies
Source:
Polycystic Kidney Research Foundation
Role:
Principal Investigator
PI:
Self
Dates:
2000 - 2002
 
Title:
Clinical Studies of Childhood SLE and Renal Vaculitis
Source:
International Society of Nephrology
Role:
Research Mentor
Dates:
2000 - 2002
 
Title:
Supplement: PKD Magnet Center of Excellence
Source:
Polycystic Kidney Research Foundation
Role:
Principal Investigator
PI:
Self
Dates:
2000 - 2001
 
Title:
Combination Drug Therapies: Targeting the EGFR Axis in PKD
Source:
Wyeth-Ayerst Research Division
Role:
Principal Investigator
PI:
Self
Dates:
2000 - 2004
 
Title:
Characterization of Biliary Cell Abnormalities in Murine ARPKD
Source:
Polycystic Kidney Research Foundation
Role:
Research Mentor
Dates:
2000 - 2002
 
Title:
The Role of TGF-alpha in the Pathogenesis of ARPKD
Source:
National Institutes of Health K08 DK-59488
Role:
Research Mentor
Dates:
2001 - 2006
 
Title:
Biliary Epithelial Cells in Murine Autosomal Recessive Polycystic Kidney Disease
Source:
Swiss National Science Foundation
Role:
Research Mentor
Dates:
2002 - 2004
 
Title:
Clinical Studies of Glomerular Disease in Children
Source:
International Society of Nephrology
Role:
Research Mentor
Dates:
2002 - 2003
 
Title:
Novel c-Src inhibitors: Preclinical Studies in PKD
Source:
Wyeth-Ayerst Research
Role:
Principal Investigator
PI:
Self
Dates:
2003 - 2005
 
Title:
Fibrosis in the Renal and Hepatobiliary Lesions of ARPKD
Source:
The Scientific and Technical Research Council of Turkey; International Society of Nephrology
Role:
Research Mentor
Dates:
2003 - 2004
 
Title:
Hepatobiliary Fibrosis in Cystic Kidney
Source:
International Society of Nephrology
Role:
Research Mentor
Dates:
2003 - 2004
 
Title:
Segment Specific Distribution and Subcellular Localization of Fibrocystin during Renal Development (P.I. - W. E. Sweeney, Jr.)
Source:
PKD Foundation
Role:
Co-Principal Investigator
Dates:
2004 - 2006
 
Title:
Inhibition of EGFR Signaling in Rodent Models of PKD
Source:
Wyeth-Ayerst Research
Role:
Principal Investigator
PI:
Self
Dates:
2004 - 2006
 
Title:
The role of c-Src in the Pathophysiology of ARPKD
Source:
Medical College of Wisconsin, Advancing a Healthier Wisconsin
Role:
Principal Investigator
PI:
Self
Dates:
2006 - 2008
 
Title:
The Role of Heat Shock Proteins in Renal Injury
Source:
National Institutes of Health (4K08-DK075470)
Role:
Mentor
PI:
Rajasree Sreedharan
Dates:
2006 - 2013
 
Title:
Integrative Biology of Childhood Kidney Disease: Research Center of Excellence in Pediatric Nephrology
Source:
National Institutes of Health (1P50DK079306)
Role:
Principal Investigator
PI:
Overall Center, Administrative Core, Project 1: Modulation of Disease Prevention in ARPKD
Dates:
2007 - 2013
 
Title:
Pre-Clinical Studies of XL-784 in PKD
Source:
Exelixis Pharmaceuticals
Role:
Principal Investigator
PI:
Self
Dates:
2007 - 2009
 
Title:
Pre-Clinical Studies of Pan Erb-B inhibition in PKD
Source:
GlaxoSmithKline Pharmaceuticals
Role:
Principal Investigator
PI:
Self
Dates:
2008 - 2010
 
Title:
Tarceva as a Therapeutic Agent for ARPKD: Preclinical Studies
Source:
OSI Pharmaceuticals
Role:
Principal Investigator
PI:
Self
Dates:
2008 - 2011
 
Title:
Pre-Clinical Studies of Nimotuzumab in PKD
Source:
YM BioSciences, Calesca
Role:
Principal Investigator
PI:
Self
Dates:
2008 - 2010
 
Title:
ARRA 2009 Supplement: Integrative Biology of Childhood Kidney Disease
Source:
National Institutes of Health (3 P50 DK079306-03S1)
Role:
Principal Investigator
PI:
Self
Dates:
2009 - 2013
 
Title:
Southeastern Wisconsin Clinical and Translational Science Award
Source:
National Institutes of Health (UL1RR031973)
Role:
Co-principal investigator
PI:
Reza Shaker, M.D.
Dates:
2010 - 2012
 
Title:
Diversity Research Supplement Award (M.Saleh, M.D.)
Source:
NIH/NIDDK Supplement to P50DK079306
Role:
Principal Investigator
PI:
Self
Dates:
2010 - 2013
 
Title:
Pre-Clinical Studies of Erb-B1 Inhibition in PKD
Source:
OSI Pharmaceuticals
Role:
Principal Investigator
PI:
Self
Dates:
2010 - 2012
 
Title:
Pre-clinical Studies of XL-647 in PKD
Source:
Symphony Evolution, Inc
Role:
Principal Investigator
PI:
Self
Dates:
2010 - 2012
 
Title:
Summer Undergraduate Students Supplement Award
Source:
NIH/NIDDK Supplement to P50DK079306
Role:
Principal Investigator
PI:
Self
Dates:
2012 - 2013
 

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Chair, 1996 Basic Science Conference:, American Society of Nephrology, 1996
Free Communications Session on Recent Advances in Polycystic Kidney Disease, American Society of Pediatric Nephrology Annual Meeting, 1997
From Bench to Bedside: New Therapeutic Approaches to Childhood Polycystic Kidney Disease, Medical College of Wisconsin, Milwaukee, WI, 01/2004 - Present
Hematuria and Glomerulonephritis, Editor’s Choice Conference, Children’s Hospital of Wisconsin, Milwaukee, WI, 06/2005 - Present
New Therapeutic Targets for Polycystic Kidney (PKD), Department of Physiology Weekly Seminar, Medical College of Wisconsin, Milwaukee, WI, 05/2008 - Present
Translational Research in PKD: New Therapies on the Horizon, Children’s Research Institute Noon Academic Conference, Children’s Hospital Health System, Milwaukee, WI, 07/2008 - Present
Childhood Polycystic Kidney Disease in the 21st Century, Department of Pediatrics Grand Rounds, University of Wisconsin, Madison, WI, 01/2009 - Present
Evolving Concepts in the Evaluation and Treatment of Childhood Polycystic Kidney Disease, Pediatric Grand Rounds, Children’s Hospital of Wisconsin, Milwaukee, WI, 01/2009 - Present
ADPKD Therapeutics on the Horizon: Hope or Hype?, Division of Internal Medicine Nephrology Grand Rounds, Medical College of Wisconsin, Milwaukee, WI, 08/2009 - Present
Renal Bedside Physiology = Clinical Nephrology, 2010 Medical Physiology Course, Medical College of Wisconsin, Milwaukee, WI, 03/2010 - Present
“Clinical Correlations: Renal Physiology”, 2011 Medical Student Physiology Course, Medical College of Wisconsin, Milwaukee, WI, 02/2011
“Clinical Correlations:: Renal Physiology.", 2012 Medical Student Physiology Course, Medical College of Wisconsin, Milwaukee, WI, 02/2012
“Mentoring: A Guide for the Perplexed Mentor and Trainee.”, Children’s Research Institute, Milwaukee, WI, 01/2013
“Opportunities for Research in Pediatric Nephrology and Polycystic Kidney Disease.”, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, 01/2013
“Translational Biology of PKD: Insights into Future Therapies”, Department of Medicine, Nephrology Research Conference, Medical College of Wisconsin, Milwaukee, WI, 01/2013
“New Approaches to Translational Research in PKD.”, MSTP Training Program, Medical College of Wisconsin, Milwaukee, WI, 06/2013
 
Regional
Polycystic Kidney Disease in Renal Explants, Polycystic Kidney Research Foundation-Baxter Health Care Workshop on the Etiology and Pathogenesis of PKD, Lake Forest, IL, 09/1987 - Present
New Insights into Renal Cystic Disease, Plenary Session on Perinatal Pediatrics and Nephrology, American Academy of Pediatrics Annual Meeting, Chicago, IL, 10/1989 - Present
Update in Pediatric Nephrology, American Academy of Pediatrics Annual Spring Meeting, Chicago, IL, 03/1993 - Present
Challenges in the Diagnosis and Management of the Child with Hypertension, Pediatrics Today Conference, Rainbow Babies and Children’s Hospital, Cleveland, OH, 02/1996 - Present
Pediatric Nephrology: What is the Role of the Routine Urinalysis in Health Care Maintenance?, American Academy of Pediatrics Annual Meeting, Chicago, IL, 04/1996 - Present
Abnormal Epidermal Growth Factor Receptor Expression in Autosomal Recessive Polycystic Kidney Disease (ARPKD), Page-Wood International Symposium on Membrane Traffic in Health and Disease, Cleveland, OH, 09/1996 - Present
Mentoring in a Turbulent Health Care Environment, Dean’s Distinguished Lecture, Wayne State University School of Medicine, Detroit, MI, 10/1997 - Present
Parke-Davis Research, Pathophysiology of Polycystic Kidney Disease: Implications for the Development of Future Therapies, Ann Arbor, MI, 01/2000 - Present
Pathophysiology of Polycystic Kidney Disease: Implications for the Development of Future Therapies, Parke-Davis Research, Ann Arbor, MI, 01/2000 - Present
Departments of Pediatrics and Medicine, The University of Iowa College of Medicine, Iowa City, IA, 04/2000 - Present
ARPKD: An Integrated Perspective, Polycystic Kidney Research Foundation Annual Meeting, Chicago, IL, 06/2000 - Present
ARPKD: What the Future Holds, Polycystic Kidney Research Foundation Annual Meeting, Chicago, IL, 06/2000 - Present
Renal Crush Syndrome, Complex Humanitarian Emergencies Course, Case Western Reserve University, Cleveland, OH, 07/2001 - Present
Departments of Medicine and Pediatrics, Ohio State University, Columbus, OH, 10/2001 - Present
Renal Complications of Complex Humanitarian Emergencies, Complex Humanitarian Emergencies Course, Case Western Reserve University, Cleveland, OH, 06/2002 - Present
Targeting the EGFR Axis in PKD, FASEB Conference on Molecular Mechanisms and Therapeutic Insights into PKD, Tucson, AZ, 08/2002 - Present
Renal Complications of Complex Humanitarian Emergencies, Complex Humanitarian Emergencies Course, Case Western Reserve University, Cleveland, OH, 06/2003 - Present
Polycystic Kidney Disease: From Molecular Pathophysiology to New Therapies, University of Miami Pediatric Nephrology Symposium, Miami, FL, 02/2005 - Present
 
National
Organ Culture in Renal Research, Conference on Cell/Tissue Culture in Renal Research, Bethesda, MD, 09/1985 - Present
New Aspects of Polycystic Kidney Disease: Pathogenesis of Renal Cyst Formation, American Society of Nephrology Annual Meeting, Washington, DC, 12/1986 - Present
In Vitro Approaches to the Study of Mammalian Nephrogenesis, New York Nephrology Society Invited Lecturer Series, New York, NY, 01/1988 - Present
Transtubular Solute Transport in Experimental Cystic Nephrogenesis, Polycystic Kidney Research Foundation-Baxter Health Care Roundtable on New Insights into Polycystic Kidney Disease, Kansas City, KS, 09/1988 - Present
Nephrology Update for the Pediatric Practitioner, American Academy of Pediatrics Annual Meeting, Seattle, WA, 05/1990 - Present
The Value of In Vitro Methods in Renal Research, American Society of Pediatric Nephrology Annual Meeting, Anaheim, CA, 05/1990 - Present
The Formation and Expansion of Renal Cysts, Renal Cystic Disorders, Annual Scientific Meeting of the National Kidney Foundation, Washington, DC, 11/1990 - Present
New Approaches to Common Urinary Tract Problems in Children, Children’s Hospital and Medical Center CME Course, Seattle, WA, 09/1991 - Present
Pediatric Nephrology Update, American Academy of Pediatrics CME Course, San Francisco, CA, 02/1992 - Present
Murine Models of Recessive PKD, NIH Conference on Molecular Genetics of Kidney Disease, Reston, VA, 03/1992 - Present
Growth Factor Alterations in Cystic Kidney Disease, Fifth International Workshop on PKD,, Kansas City, MO, 06/1992 - Present
State of the Art: Molecular and Cell Biology of Polycystic Kidney Disease, Ninth Congress of the International Pediatric Nephrology Association, Jerusalem, Israel, 09/1992 - Present
Epithelial Cell Pathophysiology in Polycystic Kidney Disease, Keystone Symposia on Epithelial and Neuronal Cell Polarity and Differentiation, Tamarron, CO, 02/1993 - Present
The Responsibilities of Mentorship, University of Washington Biomedical Research Integrity Lecture Series, Seattle, WA, 07/1993 - Present
Polycystic Kidney Disease" and "Hemolytic-Uremic Syndrome, 13th Annual Advanced Nephrology for the Consultant Postgraduate Course, San Diego, CA, 01/1994 - Present
Pathogenesis and Manifestations of Cystic Renal Disorders, Pediatric Nephrology Seminar XXI, University of Miami Postgraduate Course, Miami, FL, 02/1994 - Present
ESRD Therapy in the Infant and Young Child, Pediatric Nephrology Seminar XXI, University of Miami Postgraduate Course, Miami, FL, 02/1994 - Present
The Case Against Preemptive Transplantation, North American Pediatric Renal Transplant Cooperative Study Annual Meeting, Newport Beach, CA, 04/1994 - Present
The Cellular Basis of Renal Cyst Formation and Enlargement, Forefronts in Nephrology Symposium, International Society of Nephrology, Niagara, NY, 05/1994 - Present
Common Urinary Tract Problems in Children, Children’s Hospital and Medical Center CME Course, Seattle, WA, 09/1994 - Present
Epithelial-Mesenchymal Morphogenesis, American Society of Nephrology Annual Meeting, Orlando, FL, 10/1994 - Present
Cellular Pathophysiology of Polycystic Kidney, NKF Symposium on Genetic and Developmental Aspects of Renal Disease, National Kidney Foundation Annual Meeting, Orlando, FL, 10/1994 - Present
Molecular and Cellular Pathophysiology of Polycystic Kidney Disease, Spokane Society of Internal Medicine/National Kidney Foundation of Washington Annual Meeting, Spokane, WA, 02/1995 - Present
Molecular Genetics of Polycystic Kidney Disease, Pediatric Nephrology Seminar XXII, University of Miami Postgraduate Course, Miami, FL, 02/1995 - Present
Why Does Chronic Renal Disease in Children Progress?, Pediatric Nephrology Seminar XXII, University of Miami Postgraduate Course, Miami, FL, 02/1995 - Present
Clinical Implications of the Molecular and Cellular Biology of Polycystic Kidney Disease, 11th Annual Mitchell Rubin Lectureship in Pediatric Nephrology, 03/1995 - Present
Molecular and Cellular Biology of Normal and Abnormal Nephrogenesis, AMSPDC Frontiers in Science, San Diego, CA, 03/1995 - Present
The Cell Biology of Renal Tubular Maldevelopment, 6th International Workshop on Developmental Nephrology, Airlie, VA, 08/1995 - Present
Polycystic Kidney Disease in the Pediatric Patient, National Kidney Foundation Symposium on Polycystic Kidney Disease, National Kidney Foundation Annual Meeting, San Diego, CA, 11/1995 - Present
Progressive Nephropathy: Mechanisms and Possible Therapies, Pediatric Nephrology Seminar XXIII, University of Miami Postgraduate Course, Miami, FL, 02/1996 - Present
Pathogenesis of Renal Cystic Disease, Sixth Annual Workshop of the North American Pediatric Renal Transplant Cooperative Study, Washington, DC, 03/1996 - Present
From Bench to Bedside: Polycystic Kidney Disease, David Cornfeld, M.D. Annual Lecture, Children’s Hospital of Philadelphia, PA, 04/1996 - Present
From Bench to Bedside: Clinical Implications of Current Investigation in Polycystic Kidney Disease, Pediatric Grand Rounds, Johns Hopkins Hospital, Baltimore, MD, 10/1996 - Present
Responsibilities of Mentoring, Association of American Medical Colleges Third Annual GREAT Conference,, Scottsdale, AZ, 10/1996 - Present
Symposium on Disease Progression in Pediatric Chronic Renal Insufficiency, American Society of Pediatric Nephrology Annual Meeting, 1996
What is the Role of Molecular Genetics in Diagnosis of Renal Disease?”, Pediatric Nephrology Seminar XXIV, University of Miami Postgraduate Course, Miami, FL, 02/1997 - Present
Ethical Implications of Genetic Diagnosis of Non-Lethal Renal Diseases, Pediatric Nephrology Seminar XXIV, University of Miami Postgraduate Course, Miami, FL, 02/1997 - Present
The Contribution of GU Anomalies to ESRD: Is There Hope for Therapy?, Pediatric Nephrology Seminar XXIV, University of Miami Postgraduate Course, Miami, FL, 02/1997 - Present
Molecular Genetics of Polycystic Kidney Disease, American Society of Pediatric Nephrology Annual Meeting, Washington, DC, 05/1997 - Present
Three Rivers Clinical Pediatric Update, University of Pittsburgh School of Medicine, Pittsburgh, PA, 06/1997 - Present
Pediatric Hypertension, 45th Annual Medical Alumni Day, Children’s Hospital of Pittsburgh, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, 06/1997 - Present
Childhood Polycystic Kidney Disease, Kidney Foundation of Ohio 22nd Annual Renal Symposium, Cuyahoga Falls, OH, 09/1997 - Present
American Medical School Pediatric Department, Task Force on Housestaff Recruitment, 1997
Basic Concepts, Pediatric Nephrology Seminar XXV, University of Miami Postgraduate Course, Miami, FL, 02/1998 - Present
Autosomal Polycystic Kidney Disease: New Approaches, Pediatric Nephrology Seminar XXV, University of Miami Postgraduate Course, Miami, FL, 02/1998 - Present
Research Advances in Cystic Kidney Diseases, Keynote Address, Polycystic Kidney Research Foundation Annual Meeting, Washington, D.C, 06/1998 - Present
Cellular Pathophysiology of ARPKD: Insights into Future Therapies, Renal Research Seminar, The Mt. Sinai Medical Center, New York, NY, 11/1998 - Present
From Bench to Bedside: The Cellular Pathophysiology of Polycystic Kidney Disease, Pediatric Grand Rounds, Mt. Sinai Medical Center, New York, NY, 11/1998 - Present
New Advances in Childhood Polycystic Kidney Disease, Pediatric Grand Rounds, University of Tennessee, Knoxville, TN, 03/1999 - Present
New Insights into the Pathophysiology and Treatment of Polycystic Kidney Disease, New York Society of Nephrology, New York, NY, 03/1999 - Present
State of the Art: Polycystic Kidney Disease, 3rd Northern California Pediatric Nephrology Symposium, San Francisco, CA, 10/1999 - Present
State of the Art: Polycystic Kidney Disease, 3rd Northern California Pediatric Nephrology Symposium, San Francisco, CA, 10/1999 - Present
Department of Pediatrics, Stanford University, San Francisco, CA, 10/1999 - Present
Promising Novel Therapeutic Strategies for PKD, Clinical Science Symposium, American Society of Nephrology Annual Meeting, Miami, FL, 11/1999 - Present
New Insights into the Diagnosis and Management of Childhood UTIs, Phoenix Children’s Hospital Winter Pediatric Update 2000, Phoenix, AZ, 02/2000 - 03/2000
Hematuria: A Guide for the Perplexed, Phoenix Children’s Hospital Winter Pediatric Update 2000, Phoenix, AZ, 02/2000 - 03/2000
Therapeutic Implications of EGFR Abnormalities in Polycystic Kidney Disease, Genetics Institute Medical Advisory Board Meeting, Boston, MA, 09/2000 - Present
Proteinuria and the Nephrotic Syndrome, Children’s Hospital Winter Pediatric Update 2000, Phoenix, AZ, 2000
Department of Pediatrics, Phoenix Children’s Hospital, University of Arizona School of Medicine, 04/2001 - Present
Office Management of Hematuria: Guide for the Perplexed, Office Management of Hematuria: Guide for the Perplexed, Cleveland, OH, 04/2001 - Present
March of Dimes Visiting Professor, Department of Pediatrics, Albert Einstein College of Medicine, New York, NY, 02/2002 - Present
From Bench to Bedside: New Therapies for Polycystic Kidney Disease, New York Academy of Medicine, New York, NY, 02/2002 - Present
Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 03/2003 - Present
Departments of Pediatrics and Medicine, State University of New York – Downstate, Brooklyn, NY, 06/2003 - Present
Factors Modulating Cyst Growth: New Therapies for Polycystic Kidney Disease, Arkansas Children’s Hospital Research Institute, Little Rock, AR, 07/2003 - Present
Plenary Symposium, Pediatric Solid Organ Transplantation in the 21st Century, Pediatric Academic Societies Annual Meeting, Seattle, WA, 2003
Scientific Program Committee, American Society of Nephrology, 2004 Annual Meeting, 2003 - 2004
Hematuria and Acute Glomerulonephritis, 24th International Congress of Pediatrics, Cancun, Mexico, 08/2004 - Present
Urinary Tract Infections and Renal Scarring, 24th International Congress of Pediatrics, Cancun, Mexico, 08/2004 - Present
Molecular and Cellular Pathophysiology of Polycystic Kidney Disease, University of Washington, Department of Pediatrics, Seattle, WA, 11/2004 - Present
Plenary Symposium, Common Urinary Tract Problems in Children, 24th Congress of the International Pediatric Association, 2004
Basic Science Symposium, Non-mammalian Models of Renal Development/Disease, American Society of Nephrology Annual Meeting, 2004
Targeting the EGF Receptor in ARPKD- Special Research Conference on Innovative Therapies in ARPKD, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 05/2005 - Present
New Therapeutic Targets for Polycystic Kidney Disease (PKD), ImClone Systems Incorporated, New York, NY, 07/2005 - Present
EGFR Inhibitors: Effects on PKD Phenotypes, FASEB Summer Research Conference. New Insights in PKD: Molecular Pathways, Pathogenic Mechanisms and Translational Applications, Saxtons River, VT, 08/2005 - Present
Hematuria: A Guide for the Perplexed Physician, Penn State University College of Medicine, Milton S. Hershey Medical Center, Pediatric Residents Noon Conference, Hershey, PA, 03/2006 - Present
Renal Cystic Disease in the 21st Century: Insights for the Clinician, Penn State University College of Medicine, Milton S. Hershey Medical Center - Combined Medicine and Pediatric Grand Rounds, Hershey, PA, 03/2006 - Present
New Approaches to Therapy in PKD, Albert Einstein College of Medicine, Pediatric Grand Rounds, Bronx, NY, 02/2007 - Present
Targeting Signaling Intermediates in PKD: Therapeutic Efficacy of Src-Inhibition, Polycystic Kidney Disease, FASEB Summer Research Conference, Snowmass, CO, 07/2008 - Present
PKD: New Insights into Future Therapy”, Academic Pediatric Nephrology Symposium: Bench, Bedside and Beyond (Bernard Sidney Kaplan Festschrift), Children’s Hospital of Philadelphia, Phildelphia, PA, 05/2009 - Present
ARPKD: Current and Future Management of Progressive Renal Disease, Symposium on Autosomal Recessive Renal Disease, 15th International Congress of the International Pediatric Nephrology Association, New York, NY, 08/2010 - Present
“Future Therapies for PKD: The Impact of Translational Research.”, First Annual Dr.Demetrius Ellis Lectureship, Children’s Hospital of Pittsburgh, Pittsburgh, 02/2014
Professional Advisory Board, ARPKD/CHF Alliance
 
International
State of the Art: Experimental Cystic Kidney Disease, Seventh International Congress of Pediatric Nephrology, Tokyo, Japan, 09/1986 - Present
Development of Renal Epithelium in Organotypic Culture, Third International Workshop on Developmental Renal Physiology, Tokyo, Japan, 09/1986 - Present
Recent Advances in Developmental Nephrology: Growth Factor Control of Nephrogenesis, Seventh International Congress of Pediatric Nephrology, Tokyo, Japan, 09/1986 - Present
Organ Culture Models in the Study of Cystic Kidney Disease, Second International Workshop on Polycystic Kidney Disease, Oxford, England, 07/1987 - Present
Renal Growth and Development: In Vitro Studies of Renal Organogenesis, American Physiological Society Annual Meeting, Montreal, Canada, 10/1988 - Present
Experimental Approaches to Renal Cystic Disease, Eighth International Congress of Pediatric Nephrology, Toronto, Canada, 08/1989 - Present
Growth Factors in Normal and Abnormal Renal Differentiation, International Workshop on Developmental Renal Physiology, Montreal, Canada, 08/1989 - Present
New Developments in Pediatric Nephrology, American Academy of Pediatrics CME Course, Calgary, Alberta, CAN, 07/1991 - Present
Altered Epithelial Polarity and Growth Factor Responses in Metanephric Maldevelopment, Fifth International Workshop on Developmental Renal Physiology, Tremezzo, Italy, 08/1992 - Present
Cellular Pathophysiology of Polycystic Kidney Disease, Twelfth International Congress of Nephrology, Jerusalem, Israel, 06/1993 - Present
The Biological Basis of Renal Dysplasia and Renal Cystic Disease, Annual Kidney Research Aid Fund Lecture, Institute of Child Health, London, England, 03/1994 - Present
Progress in Pediatric Renal Disease, Child Health 200 - 2nd World Congress and Exposition, Pediatric Postgraduate Course, Vancouver, British Columbia, Canada, 06/1995 - Present
Pathophysiology of Renal Cyst Formation: Implications for the Clinician, 10th Congress of the International Pediatric Nephrology Association, Santiago, Chile, 08/1995 - Present
Cellular Pathophysiology of Cystic Kidney Disease: Insights into Future Therapies, 7th International Workshop on Developmental Nephrology, Stockholm, Sweden, 09/1998 - Present
Cellular Pathophysiology of Polycystic Kidney Disease, 11th Congress of the International Pediatric Nephrology Association, London, England, 09/1998 - Present
Polycystic Kidney Disease: Insights into Future Therapies, Princess Lilian Cardiology Foundation International Symposium, Brussels, Belgium, 10/1998 - Present
Polycystic Kidney Disease, Brandeis Symposium - 30 Years of Pediatric Nephrology: Past, Present and Future, Freiberg, Germany, 06/1999 - Present
Developmental Biology of Polycystic Kidney Disease, Annual Meeting of the Japanese Society of Nephrology, Tokyo, Japan, 06/1999 - Present
Annual Meeting of the Japanese Society of Nephrology, Cellular Pathophysiology of Polycystic Kidney Disease, Tokyo, Japan, 06/1999 - Present
Polycystic Kidney Disease, Departments of Pediatrics and Medicine, Kobe University, Kobe, Japan, 06/1999 - Present
Factors Modulating Cyst Growth: New Therapeutic Targets in PKD, American Society of Pediatric Nephrology Annual Meeting, Toronto, Ontario, Canada, 10/2000 - Present
Department of Pediatrics, Khon Kaen University, Khon Kaen, Thailand, 02/2001 - Present
Renal Emergencies, Management of Complex Humanitarian Emergencies: Focus on Children and Families, Khon Kaen University, Khon Kaen, Thailand, 02/2001 - Present
Department of Pediatrics, National University of Laos, Faculty of Medical Sciences, Vientiane, Laos, 02/2001 - Present
From Laboratory Investigation to Patient Bedside: Polycystic Kidney Disease in the 21st Century, Jean Pouliot Lectureship, Montreal Children’s Hospital Research Institute and Hospital Sainte-Justine, Montreal, Canada, 03/2001 - Present
Research Update: Cellular Pathophysiology of Polycystic Kidney Disease, Montreal Children’s Hospital Research Institute, Montreal, Montreal, Canada, 03/2001 - Present
Departments of Medicine and Pediatrics, Wakayama Medical School, Wakayama, Japan, 11/2002 - Present
Molecular and Cellular Pathophysiology of PKD, Plenary Speaker, Kinki Pediatric Nephrology Meeting, Osaka, Japan, 11/2002 - Present
Renal Cystic Disease in the 21st Century: New Insights for the Clinician, 15th Israel Medical Week, Children’s Day in Medicine, Tel Aviv, Israel, 03/2004 - Present
New Insights into the Treatment of Polycystic Kidney Disease, Plenary Speaker, 13th Congress of the International Pediatric Nephrology Association, Adelaide, Australia, 09/2004 - Present
Functional Genomics: New Therapies for PKD in the 21st Century, 9th Asian Congress of Pediatric Nephrology, Beijing, China, 10/2005 - Present
Clinical Evaluation of the Abnormal Urinalysis, National University of Nigeria, Pediatric Grand Rounds, Abuja, Nigeria, 10/2006 - Present
Plenary Symposium: New Approaches to UTI-VUR, 25th International Congress of Pediatrics, Athens, Greece, 2007
IPNA Symposium: Update on Common Childhood Kidney Problems, 25th International Congress of Pediatrics, Athens, Greece, 2007
Hematuria and Glomerulonephritis: A Guide for the Perplexed Physician, Editor’s Choice Conference, Krakow, Poland, 06/2008 - Present
Renal Cystic Disease: New Insights for the Clinician, Editor’s Choice Conference, Krakow, Poland, 06/2008 - Present
New Therapies for PKD, Annual Meeting of the European Society of Pediatric Nephrology, Lyon, France, 09/2008 - Present
Translational Research in PKD: New Therapies on the Horizon, 2nd Gerry Schwartz and Heather Reisman International Congress on Children with Chronic Diseases, Jerusalem, Israel, 12/2008 - Present
“Developing therapies for chronic genetic diseases: PKD as a model” (Plenary Session) and “Challenges of Mentoring in the Current Pediatric Academic Environment”(Educational Symposium), International Congress on Childhood Chronic Diseases, Jerusalem, Israe, 12/2012
“Translational Therapies for Childhood Polycystic Kidney Disease”, Pediatric Academic Societies Invited Plenary Lecture; Symposium on “Hot Topics in Pediatric Research”, Vancouver, B.C., 05/2014
 

COMMITTEE SERVICE:
Medical College of Wisconsin
1986 - 1988 Member, Career Counseling Committee, University of Pittsburgh School of Medicine
1991 - 1993 Member, Committee on Issues in Biomedical Research Integrity, University of Washington
1991 - 1995 Faculty Senator, University of Washington
1991 - 1995 Member, Faculty Council on Scientific Affairs, University of Washington
1995 - 2004 Member, Executive Committee, Case Western Reserve University School of Medicine
1996 - 2002 Member, Strategic Planning Committee, Office of the Dean, Case Western Reserve University School of Medicine
1996 - 2004 Member, Honorary Degree Committee, Case Western Reserve University
1997 - 1998 Chair, Chair Search Committee, Department of Medicine, Case Western Reserve University School of Medicine
1998 - 2004 Member, Tenure Compensation Committee, Case Western Reserve School of Medicine
1998 - 2001 Member, Chair Search Committee, Department of Reproductive Biology, Case Western Reserve University School of Medicine
1999 - 2000 Chair, Chair Search Committee, Department of Psychiatry, Case Western Reserve University School of Medicine
1999 - 2004 Member, Program Advisory Committee, Howard Hughes Medical Institute Biomedical Research Support Program, Case Western Reserve University School of Medicine
1999 - 2001 Member, Chair Search Committee, Department of Family Medicine, Case Western Reserve University School of Medicine
1999 - 2001 Member, Faculty Council, Case Western Reserve University School of Medicine
2000 - 2004 Member, Clinical Research Scholars Program Advisory Committee, Case Western Reserve University School of Medicine
2002 - 2003 Member, Chair Search Committee, Department of Orthopedics, Case Western Reserve University School of Medicine
2010 - 2015 Member, Scientific Program Advisory Committee, Master of Science in Clinical & Translational Health, Medical College of Wisconsin
2010 - 2015 Member, Scientific Program Advisory Committee, Master of Science in Clinical & Translational Health, Medical College of Wisconsin
2011 Internal Advisor, Children’s Environmental Health Sciences Core Center
2011 - Present Member, CTSI Citizens Advisory Council, CTSI Community Engagement Key Function
2011 Chair, Research Committee, Department of Pediatrics, Medical College of Wisconsin
2011 - 2013 Member, Transitional Leadership Group, Department of Pediatrics, Medical College of Wisconsin
2011 - Present Member, Research Advisory Board, Cancer Cell Biology Research Program, Medical College of Wisconsin
2011 - Present Board Member, Internal Advisory Board, Cancer Center, Medical College of Wisconsin
2012 Member, Finance Committee, Department of Pediatrics, Medical College of Wisconsin
2012 - Present Member, Internal Advisory Board, Medical College of Wisconsin Cancer Center
 
Hospital
1982 - 1988 Member, Utilization Review Committee, Children's Hospital of Pittsburgh
1983 - 1988 Member, Animal Research and Care Committee, Children's Hospital of Pittsburgh
1983 - 1988 Member, Resident Selection Committee, Children's Hospital of Pittsburgh
1991 - 1994 Chair, Animal Care and Use Committee, Children's Hospital and Medical Center, Seattle
1993 - 1995 Member, Quality Improvement/Peer Review Committee, Children's Hospital and Medical Center, Seattle
1993 - 1995 Member, Managed Care Committee, Department of Medicine, Children's Hospital and Medical Center, Seattle
1993 - 1995 Chair, Fellowship Funding Committee, Children's Hospital and Medical Center, Seattle
1993 - 1995 Member, Contracts Committee, Children's University Medical Group, Seattle
1994 - 1995 Member, Regional Outreach Task Force, Children’s Hospital and Medical Center, Seattle
1994 - 2004 Co-Chair, Facilities Design Team, Children’s Hospital and Medical Center, Seattle
1995 - 2004 Member, Executive Committee, Clinical Council, University Hospitals of Cleveland
1995 - 2004 Member, Clinical Council, University Hospitals of Cleveland
1995 - 2004 Chair, Children’s Research Foundation, Cleveland
1995 - 2004 Member, Clinical Leadership Advisory Committee, University Hospitals of Cleveland
1995 - 2004 Member, University Primary Care Physicians / University Faculty Practice Association Liaison Committee, University Hospitals of Cleveland
1995 - 2004 Member, Council of Clinical Chairs, University Hospitals of Cleveland
1995 - 1998 Member, Board of Directors, University Faculty Practice Association, University Hospitals of Cleveland
1996 - 1998 Member, Executive Committee, University Faculty Practice Association
1996 - 2003 Member, Clinical Council Credentialing Subcommittee, University Hospitals of Cleveland
1997 - 2004 Member, Minority Faculty Development Committee, University Hospitals of Cleveland
1998 - 2003 Member, Internal Affiliation Committee, University Hospitals of Cleveland
1999 - 2003 Member, Executive Board, University Hospitals Faculty Services
1999 - 2003 Member, Policy Advisory Committee, Research Institute, University Hospitals of Cleveland
1999 - 2003 Member, Operational Advisory Committee, University Hospital Faculty Services
1999 - 2003 Member, Space Planning Committee, Research Institute, University Hospitals of Cleveland
1999 - 2004 Member, Ad Hoc Committee, Safety of Polyvinylchloride/Phthalates, University Hospitals of Cleveland
1999 - 2004 Member, Mary B. Lee Endowment Fund Committee, University Hospitals of Cleveland
2000 - 2003 Member, Executive Committee, University Hospitals Research Institute, Cleveland
2000 - 2003 Member, Quality Monitoring Council, University Hospitals of Cleveland
2000 - 2003 Member, Performance Indicators Advisory Committee, University Hospitals of Cleveland
2000 - 2004 Chair, Educational and Research Mission Workgroup, University Hospitals of Cleveland
2000 - 2003 Member, Conflict of Interest Policy Development Committee, University Hospitals Research Institute, Cleveland
2000 - 2004 Member, CWRU/UHC Research and Intellectual Property Task Force, University Hospitals of Cleveland
2001 - 2004 Member, Medical Resource Management Steering Committee, University Hospitals of Cleveland
2002 - 2003 Member, Blueprint for Change Committee (Rainbow Babies & Children’s Hospital Service Line), University Hospitals of Cleveland
2002 - 2003 Member, Affiliation Committee, University Hospitals and Case Western Reserve University, Cleveland
2003 - 2004 Chair, Executive Steering Committee, Children’s Research Foundation / ECG Management Consultants Project
2005 - 2012 Member, Strategic Planning Committee, Children’s Hospital and Health System Foundation, Milwaukee
2007 - 2012 Chair, Children’s Research Campaign Sub-Committee, Children’s Hospital and Health System Foundation, Milwaukee
2013 - Present Ex Officio Research Advisor, Children’s Research Institute
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Student Education
2013 Senior Mentor, K-12 Club, Department of Pediatrics
2013 Advisor, T-32 Training Grant Program, Department of Pediatrics
2013 Facilitator, “Professionalism”; 3rd year MCW Medical Students
 

EXTRAMURAL TEACHING:
Medical Student Education
1992 - 1995 University of Washington, 1992-1995 Regular Lecturer, Pediatrics 512P: Seminars in Human Embryology and Teratology
1992 - 1995 University of Washington, Regular Lecturer, Pediatrics 512P: Seminars in Human Embryology and Teratology
 
Continuing Medical Education
02/1992 Stanford University, Palo Alto, California, Department of Molecular and Cellular Physiology
02/1993 Stanford University, Palo Alto, CA, Department of Molecular and Cellular Physiology
06/1994 Mayo Clinic, Rochester, Minnesota, Department of Medicine
12/1994 University of Alabama at Birmingham, Department of Medicine
03/1995 State University of New York - Buffalo, NY, Department of Pediatrics
12/1995 Indiana University School of Medicine, Indianapolis, IN, Departments of Medicine and Anatomy and Cell Biology
01/1996 Harvard University and the Children’s Hospital, Boston, MA, Departments of Pediatrics and Anesthesia
04/1996 University of Pennsylvania School of Medicine, Philadelphia, PA, Department of Pediatrics
10/1996 Johns Hopkins University School of Medicine, Baltimore, Maryland, Department of Pediatrics
10/1997 Wayne State University School of Medicine, Children’s Hospital of Michigan, Detroit, Michigan, Department of Pediatrics
11/1998 Mt. Sinai School of Medicine, New York, NY, Departments of Pediatrics and Medicine
02/1999 National University of Laos, Faculty of Medical Sciences, Vientiane, Laos, Department of Pediatrics
02/1999 Khon Kaen University, Khon Kaen, Thailand, Department of Pediatrics
10/1999 University of California San Francisco, San Francisco, CA, Department of Pediatrics
06/2003 Emory University School of Medicine, Atlanta, GA, Department of Pediatrics
11/2004 University of Washington School of Medicine, Seattle, WA, Department of Pediatrics
03/2006 Penn State University, Milton S. Hershey Medical Center, Hershey, PA, Department of Pediatrics
02/2007 Albert Einstein College of Medicine, Children’s Hospital at Montefiore, New York, NY, Departments of Pediatrics and Medicine
12/2008 Technion University and Rambam Medical Center, Haifa, Israel, Departments of Pediatrics and Physiology
01/2009 University of Wisconsin, School of Medicine and Public Health, Madison, WI, Department of Pediatrics
 
Graduate Student Education
1987 Albert Einstein College of Medicine, Bronx, New York, Department of Pediatrics
10/1991 Washington University, St. Louis, Missouri, Department of Medicine
1993 University of Toronto and Hospital for Sick Children, Toronto, Canada, Departments of Medicine and Pediatrics
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Undergraduate Students
Katherine Eisenbrown, Medical College of Wisconsin, 2011 - Present
 
Postdoctoral Students
Megan Determan, Medical College of Wisconsin, 2010 - Present
Ameya Patil, M.D., Medical College of Wisconsin, 2013 - Present Research, Current Position: Assistant Professor of Pediatrics
 

EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
Ali Harari, M.D., 1997 - 1999
Crystal Murcia, 1998 - 2001
 
Postdoctoral Students
Yuko Ozawa, M.D., Ph.D., Nagoya University, 1989 - 1991
Ruth McDonald, M.D., 1990 - 1993
Consuelo Glen, M.D., 1990 - 1993
Jeroen Nauta, M.D., Ph.D., 1990 - 1993
Consuelo Glen, M.D., 1990 - 1993
Gregory Sliman, M.D., 1991 - 1994
Judith Pugh, M.D., 1991 - 1994
John Brandt, M.D., 1992 - 1995 Professor of Pediatrics; Director, Pediatric Nephrology; University of New Mexico, Albuquerque, NM
Robert Holleman, M.D, 1993 - 1996 Professor of Clinical Pediatrics; Director, Pediatric Residency Program and Chief of Pediatric Nephrology; University of South Carolina School of Medicine ,Columbia, SC
Nicole Becker, M.D., 1993 - 1996
Mark Joseph, M.D., 1994 - 1997 Associate Professor of Pediatrics (Nephrology); Phoenix Children’s Hospital, Phoenix, AZ
Annamaria T. Kausz, M.D., M.S., 1994 - 1998 Associate Professor of Pediatrics and Medicine (Nephrology); Tufts University School of Medicine, Boston, MA
Koichi Nakanishi, M.D., Ph.D., 1998 - 2000 Associate Professor and Chief, Pediatric Nephrology; Wakayama University Medical Center, Wakayama, Japan
Noel Murcia, Ph.D., 1998 - 2000 Clinical Assistant Professor, Department of Pediatrics; Case Western Reserve University, Cleveland, OH
Dana Schwartz, Case Western Reserve University, 1999 - 2002
Fatima Tsalicova, M.D., 1999 - 2000 Staff Nephrologist, Institute of Pediatrics and Children’s Surgery; Moscow, Russia
Suwanee Wisanuyotin, M.D., 2000 - 2002 Associate Professor of Pediatric Nephrology; Director, Pediatric Residency Program; Khon Kaen University, Khon Kaen, Thailand
Kiyoshi Hamahira, M.D., 2000 - 2003 Chief, Pediatric Renal Unit; Himeji Red Cross Hospital, Himeji, Japan
Katherine MacRae Dell, M.D., 2001 - 2006 Professor Pediatrics; Director, Division of Pediatric Nephrology; Case Western Reserve University, Cleveland, OH
Aysun Bayazit, M.D., 2002 - 2003 Professor and Director, Department of Pediatric Nephrology; Cukurova University School of Medicine, Adana, Turkey
Rodo O. von Vigier, M.D., 2002 - 2004 Professor of Pediatrics; Director, Pediatric Nephrology; University of Berne, Basil, Switzerland
Ali Duzova, M.D., 2003 - 2004 Associate Professor, Division of Pediatric Nephrology; Hacettepe University, Ankara, Turkey
Nahoko Yata, M.D., Ph.D., 2005 - 2006 Associate Professor, Wakayama University Medical Center, Wakayama, Japan
Frank Park, Ph.D., 2007 - Present Associate Professor, Department of Medicine (Nephrology); Medical College of Wisconsin, Milwaukee, WI
Eduardo Lau, Ph.D., 2007 - Present
Carol Moreno-Quinn, M.D., Ph.D., 2007 - Present Assistant Professor, Department of Physiology (Genetics); Medical College of Wisconsin, Milwaukee, WI
Nadezda Zheleznova, Ph.D., 2007 - 2009 Post Doctoral Fellow, Department of Physiology; Medical College of Wisconsin, Milwaukee, WI
Priya Pais, MBBS, 2007 - Present
Ashraf El-Meanawy, M.D., Ph.D., 2007 - Present
Xiaogang Li, Ph.D., Associate Professor, University of Colorado, 2007 - 2009 Research
Kandai Nozu M.D.;PhD, Kobe University, 2010 - 2013 Research, Current Position: Associate Professor of Pediatrics; Director Pediatric Nephrology
Shireen Hashmat, MBBS, University of Chicago School of Medicine, 2012 - 2015 Research, Current Position: Assistant Professor of Pediatrics
 

PATENT:
2006 - Present Allelic Series of Genomic Modification in Cells - Application Serial Number 09/103,846. Filed 12/04; Awarded 2006 Richard P. Woychik, Ph.D., Terry R. Magnuson, Ph.D., and Ellis D. Avner, M.D.
08/2009 - Present Methods of Modulating Cell Proliferation and Cyst Formation in Polycystic Kidney and Liver Diseases. Patent # 20080167382 Published August 2009. Ellis D. Avner, Richard Roman, William E. Sweeney.


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Avner ED, Satz J, Plotkin SA: Hypoglycorrhachia in young infants with viral meningitis. J Pediatr 87:833-834, 1975. PMID: 1185362
2. Avner ED, Harmon WE, Ingelfinger JR, Levey RH, Grupe WE. Mortality of chronic hemodialysis comparable to that of renal transplantation in pediatric end-stage renal disease. Proc Clin Dial Transplant Forum. 1979;9:1-4.
3. Avner ED, Harmon WE, Grupe WE, Ingelfinger JR, Eraklis AJ, Levey RH: Mortality of chronic hemodialysis and renal transplantation in pediatric end-stage renal disease. Pediatrics 67:412-416, 1981. PMID: 399499
4. Avner ED, Ellis D, Jaffe R, Bowen A: Neonatal radiocontrast nephropathy simulating infantile polycystic kidney disease. J Pediatr 100:85-87, 1982. PMID: 7199081
5. Avner ED, Ellis D, Temple T, Jaffe R: Metanephric development in serum-free organ culture. In Vitro Cell Dev Biol 18:675-682, 1982. PMID: 7129481
6. Avner ED, Ingelfinger JR, Herrin JT, Link DA, Marcus E, Tolkoff-Rubin NE, Russell-Getz L, Rubin RH: Single-dose amoxicillin therapy of uncomplicated pediatric urinary tract infections. J Pediatr 102:623-627, 1983. PMID: 6339708
7. Ellis D, Avner ED, Transue D, Yunis EJ, Drash AL, Becker DJ: Diabetic nephropathy in adolescence: Appearance during improved glycemic control. Pediatrics 71:824-829, 1983. PMID: 6340051
8. Avner ED, Sweeney WE, Ellis D: Cyst formation in metanephric organ culture induced by cis-dichlorodiammine platinum (II). Experientia 39:74-76, 1983. PMID: 6681778
9. Avner ED, Jaffe R, Temple T, Ellis D, Chung AE: The development of renal basement membrane glycoproteins in metanephric organ culture. Lab Invest 48:263-268, 1983. PMID: 6827806
10. Avner ED, Ellis D, Jaffe R: Veno-occlusive disease of the liver associated with cysteamine treatment of nephropathic cystinosis. J Pediatr 102:793-796, 1983. PMID: 6842343
11. Avner ED, Sweeney WE, Piesco NP, Ellis D: A new model of glucocorticoid- induced cystic metanephric maldevelopment. Experientia 40:489-490, 1984. PMID: 6723915
12. Avner ED, Piesco NP, Sweeney WE, Studnicki FM, Fetterman GH, Ellis D: Hydrocortisone-induced cystic metanephric maldevelopment in serum-free organ culture. Lab Invest 50:208-218, 1984. PMID: 6694360
13. Avner ED, Sweeney WE, Finegold DN, Piesco NP, Ellis D: Sodium-potassium adenosine tri-phosphatase activity mediates cyst formation in metanephric organ culture. Kidney Int 28:447-455, 1985. PMID: 2999498
14. Avner ED, Sweeney WE, Piesco NP, Ellis D: Growth factor requirements of metanephric differentiation in serum-free murine organ culture. In Vitro Cell Dev Bio 21:297-304, 1985. PMID: 3894316
15. Ellis D, Avner ED, Rosenthal JT, Taylor RJ, Young LW, Palumbi MA, Hakala TR: Renal function and somatic growth in pediatric cadaveric renal transplant recipients receiving prednisone-cyclosporine immunosuppression. Am J Dis Child 139:1161-1167, 1985. PMID: 3904407
16. Avner ED, Sweeney WE, Piesco NP, Ellis D: Regression of genetically determined polycystic kidney disease in murine organ culture. Experientia 42:77-80, 1986. PMID: 3943602
17. Ellis D, Avner ED: Renal failure and dialysis therapy in children with hepatic failure in the perioperative period of orthotopic liver transplantation. Clin Nephrol 25:295-303, 1986. PMID: 3524924
18. Ellis D, Avner ED, Kurs-Lasky M, Richards M, Becker DJ: Effects of improved glycemic control on microalbuminemia in adolescents with insulin-dependent diabetes mellitus. Int J Pediatr Nephrol 7:31-39, 1986. PMID: 3957559
19. Ellis D, Turocy JW, Sweeney WE, Avner ED: Partial characterization and ontogeny of renal cytosolic glucocorticoid receptors in mouse kidney. J Steroid Biochem 24:997-1003,1986. PMID: 3724151
20. Ellis D, Avner ED, Starzl TE: Renal failure in children with hepatic failure undergoing liver transplantation. J Pediatr 108:393-398, 1986. PMID: 3512808. 2010 PMCID PMC2976655.
21. Ptachinski RJ, Burckart GJ, Rosenthal JT, Venkataramanan R, Howrie DL, Taylor RJ, Avner ED, Hakala TR: Cyclosporine pharmacokinetics in children following cadaveric renal transplantation. Transplant Proc 18:766-768, 1986.
22. Avner ED, Sweeney WE, Piesco NP, Ellis D: Triiodothyronine-induced cyst formation in metanephric organ culture: The role of increased Na-KATPase activity. J Lab Clin Med l09:441-454, 1987. PMID: 3029256
23. Osorio AM, Thun MJ, Novak RF, Van Cura EJ, Avner ED: Silica and glomerulonephritis. Am J Kidney Dis 9:224-231, 1987. PMID: 3030097
24. Ellis D, Tran SD, Eagon PK, Avner ED: Reversible inhibition of cytosolic glucocorticoid receptors by mercurial agents. Application in the measurement of total and unoccupied receptors. J Recept Res 7:761-774, 1987. PMID: 3656273
25. Avner ED, Studnicki FM, Young MC, Sweeney WE, Piesco NP, Ellis D, Fetterman GH: Congenital murine polycystic kidney disease: I. The ontogeny of tubular cyst formation. Pediatr Nephrol 1:587-596, 1987. PMID: 3153336
26. Ellis D. Sothi TD, Avner ED: Glucocorticoids modulate renal glucocorticoid receptors and Na-K ATPase activity. Kidney Int 32:464-471, 1987. PMID: 2828745
27. Avner ED: Renal cystic disease: Insights from recent experimental investigations. Nephron 48:89-93, 1988. PMID: 3278246
28. Curto KA, Sweeney WE, Avner ED, Piesco NP, Curthoys NP: Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of the mouse kidney. J Histochem Cytochem 36:159-166, 1988. PMID: 2891746
29. Avner ED, Piesco NP, Sweeney WE, Ellis D: Renal epithelial development in organotypic culture. Pediatr Nephrol 2:92-99, 1988. PMID: 3153007
30. Avner ED, Sweeney WE, Ellis D: Congenital murine polycystic kidney disease: II. Pathogenesis of tubular cyst formation. Pediatr Nephrol 2:210-218, 1988. PMID: 2856368
31. Ellis D, Sothi TD, Curthoys NP, Ballou B, Avner ED: Regulation of glucocorticoid receptors and Na-K ATPase activity by hydrocortisone in proximal tubular epithelial cells. In Vitro Cell Dev Biol 24:811-816, 1988. PMID: 2900828
32. Morris SM, Kepka DM, Sweeney WE, Avner ED: Abundance of mRNAs encoding urea cycle enzymes in fetal and neonatal mouse liver. Arch Biochem Biophys. 269:175-180, 1989. PMID: 2464968
33. Ellis D, Coonrod BA, Dorman JS, Kelsey SF, Becker DJ, Avner ED, Orchard TJ: Choice of urine sample predictive of microalbuminuria in patients with insulin-dependent diabetes mellitus. Am J Kidney Dis. 13:321-328, 1989. PMID: 2705450
34. Avner ED, Sweeney WE, Ellis D: In vitro modulation of tubular cyst regression in murine polycystic kidney disease. Kidney Int 36:960-968, 1989. PMID: 2557482
35. Avner ED, Sweeney WE Jr. Polypeptide growth factors in metanephric growth and segmental nephron differentiation. Pediatr Nephrol. 1990 Jul;4(4):372-7.
36. Avner ED, Sweeney, WE: Polypeptide growth factors in metanephric growth and segmental nephron differentiation. Pediatr Nephrol 4:372-377, 1990. PMID: 2206907
37. Tapper D, Watkins S, Burns M, Hickman RO, Avner ED: Comprehensive management of renal failure in infants. Arch Surg 125:1276-1281, 1990.
38. Avner ED: Polypeptide growth factors and the kidney: a developmental perspective. Pediatr Nephrol 4:345-353, 1990. PMID: 2206902
39. Morris SM Jr, Sweeney WE Jr, Kepka DM, O'Brien WE, Avner ED. Localization of arginine biosynthetic enzymes in renal proximal tubules and abundance of mRNA during development. Pediatr Res. 1991 Feb;29(2):151-4.
40. Sweeney WE, Avner ED: Intact organ culture of murine metanephros. J Tissue Cult Methods 13:163-168, 1991.
41. McDonald R, Avner ED: Cystic disease in children. Seminars Nephrol 11:632-643, 1991. PMID: 1767136
42. Sweeney WE, Avner ED: Pathophysiology of renal tubular cyst formation in murine models of polycystic kidney disease. Contributions to Nephrology 97:23-34, 1992. PMID: 1633715
43. Sweeney WE Jr, Avner ED. Pathophysiology of renal tubular cyst formation in murine models of polycystic kidney disease. Contrib Nephrol. 1992;97:23-34.
44. Kemper KJ, Avner ED. The case against screening urinalyses for asymptomatic bacteriuria in children. Am J Dis Child. 1992 Mar;146(3):343-6.
45. Kemper KJ, Avner ED: The case against screening urinalysis for asymptomatic bacteriuria in children. Am J Dis Child 146:343-346, 1992. PMID: 1543183
46. Avner ED, Sweeney WE Jr, Nelson WJ. Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease. Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7447-51. PMCID: PMC49727
47. Fouser L, Avner ED: Physiology and cell biology update: Normal and abnormal nephrogenesis. Am J Kidney Dis 21:64-70, 1993. PMID: 8418629
48. Nauta J, Sweeney WE, Ozawa Y, Avner ED: Dual renal tubular and biliary epithelial abnormalities in a new murine model of autosomal recessive polycystic kidney disease. Pediatr Nephrol 7:163-172, 1993. PMID: 8476712
49. Avner ED: Renal developmental diseases. Semin Nephrol 13:427-435, 1993. PMID: 8210806
50. Avner ED: Epithelial polarity and differentiation in polycystic kidney disease. J Cell Science (Suppl) 17:217-222, 1993. PMID: 8144700
51. Ozawa Y, Nauta J, Sweeney WE, Avner ED: A new murine model of autosomal recessive polycystic kidney disease. Jap J Nephrol 35:349-354, 1993. PMID: 8341011
52. Moyer JH, Lee-Tischler MJ, Kwon HJ, Schrick JJ, Avner ED, Sweeney WE, Godfrey VL, Cacheiro NLA, Wilkinson JE, Woychik RP: Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. Science 264:1329-1333, 1994. PMID: 8191288
53. Brandt J, Fouser L, Watkins S, Zelikovic I, Tarr P, Nazar-Stewart V, Avner ED: E. coli 0157:H7 associated hemolytic uremic syndrome after ingestion of contaminated hamburgers. J Pediatr 125: 519-526, 1994. PMID: 7931869
54. Tapper D, Tarr P, Avner ED, Brandt J, Waldhausen J: Lessons learned in the management of hemolytic uremic syndrome in children. J Pediatr Surg 30: 158-163, 1995.
55. Avner ED (ed): Pediatric fluid and electrolyte therapy. Pediatr Ann 24: 9-54, 1995.
56. Avner ED: Disorders of sodium and water balance. Pediatr Ann 24: 23-30, 1995. PMID: 7715960
57. Avner ED: Gene time for polycystic kidney disease. Lancet 344:833-834, 1994. PMID: 7916394
58. Sliman GH, Winters WD, Shaw DW, Avner ED: Hypercalciuria and nephrocalcinosis in the Oculocerebrorenal Syndrome J. Urol 153: 1244-1246, 1995. PMID: 7869519
59. Avner ED, Chavers B, Sullivan EK, Tejani A: Renal transplantation and chronic dialysis in children and adolescents: The 1993 annual report of the North American Renal Transplant Cooperative Study. Pediatr Nephrol 9: 61-73, 1995. PMID: 7742226
60. Becker N, Avner ED: Congenital nephropathies and uropathies. Pediatr Clin North Amer 42: 1319-1341, 1995. PMID: 8614589
61. Orellana S, Avner ED: Cystic maldevelopment of the kidney. Sem Nephrol 15: 341-352, 1995. PMID: 7569413
62. Nauta J, Sweeney WE, Rutledge J, Avner ED: Biliary epithelial cells from mice with congenital polycystic kidney disease are hyperresponsive to epidermal growth factor. Pediatr Res 37: 755-763, 1995. PMID: 7651760
63. Orellana S, Sweeney WE, Neff C, Avner ED: Epidermal growth factor receptor expression is abnormal in murine polycystic kidney. Kidney Int 47:490-499. 1995. PMID: 7723235
64. Holleman RC, Avner ED: Renal cystic disorders. Curr Pediatr 5: 80-85, 1995.
65. Pugh J, Sweeney WE, Avner ED: The tyrosine kinase activity of the EGF receptor in murine metanephric organ culture. Kidney Int 47: 774-781, 1995. PMID: 7752576
66. Holleman R, Avner ED: Clinical quiz: Hypertension in an adolescent with a hypokalemic metabolic acidosis. Pediatr Nephrol 9:783-784, 1995. PMID: 8747126
67. Guay-Woodford L, Muechar G, Hopkins S, Avner ED, Germino G, Guillot A, Herrin J, Holleman R, Irons D, Primack W, Thompson P, Waldo F, Lunt P, Zerres K: The severe perinatal form of Autosomal Recessive Polycystic Kidney Disease maps to chromosome 6p21.1-p12: Implications for genetic counseling. Am J Hum Genet 56: 1101-1107, 1995. PMID: 7726165
68. Johnson JA, Grande JP, Roche PC, Sweeney WE, Avner ED, Kumar R: 1α25 Dihydroxyvitamin D3 receptor ontogeny in fetal renal development. Am J Physiol 38:F419-F428, 1995. PMID: 7573491
69. Becker N, Rutledge JC, Avner ED: Clinical quiz: Acute renal failure in an adolescent with JRA. Pediatr Nephrol 9:785-787, 1995. PMID: 8747127
70. Foreman JW, Benson LL, Wellons M, Avner ED, Sweeney WE, Nissim IL, Nissim IT: Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester (CDE) model of cystinosis. J Am Soc Nephrol 6:269-272, 1995. PMID: 7579095
71. Yoder BK, Richards WG, Sweeney WE, Wilkinson JE, Avner ED, Woychik RP: Insertional mutagenesis and molecular analysis of a new gene associated with polycystic kidney disease. Proceed Assoc Amer Physicians 107: 314-323, 1995.
72. Orellana S, Neff C, Sweeney WE, Avner ED: Novel Madin Darby canine kidney cell clones exhibit unique phenotypes in response to morphogens. In Vitro Cell Dev Biol 32:329-339, 1996. PMID: 8842747
73. Jabs K, Sullivan EK, Avner ED, Harmon WE: Alternate-day steroid dosing improves growth without adversely affecting graft survival of long term graft function: A report of the North American Pediatric Renal Transplant Cooperative Study. Transplantation 61:31-36. 1996. PMID: 8560569
74. Guay-Woodford LM, Bryda EC, Christine B, Lindsey JR, Collier WR, Avner ED, E'Eustachio P, Flaherty L. Evidence that two phenotypically distinct mouse PKD mutations, bpk and jcpk, are allelic. Kidney Int 50:1158-1165, 1996. PMID: 8887273
75. Yoder BK, Richards WG, Sommardahl CS, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP: Functional correction of the renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA. Kidney Int 50:1240-1248, 1996. PMID: 8887283
76. Wilson P, Avner ED: Renal maldevelopment of the kidney and urinary tract. Pediatr Nephrol 10:828-830, 1996.
77. Lens XM, Onuchic LF, Wu G, Hayashi T, Daoust M, Mochizuki T, Santarina B, Stockwin JM, Mucher G, Becker J, Sweeney WE, Avner ED, Guay-Woodford L, Zerres K, Somlo S, Germino GG: An integrated genetic and physical map of the autosomal recessive polycystic kidney disease region. Genomics 41: 463-466, 1997. PMID: 9169147
78. Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP. Differential rescue of the renal and hepatic disease in an ARPKD mouse mutant: a new model to study the liver lesion. Amer J Pathol 150: 2231-2241, 1997. PMID: 9176412
79. Becker N, Avner ED, Watkins, SL: Improved outcome of young children on nightly automated peritoneal dialysis. Pediatr Nephrol 11:676-679, 1997. PMID: 9438640
80. Sweeney WE, Avner ED: The role of hepatocyte growth factor at progressive stages of metanephric development. In Vitro Cell & Develop Biol 34:189-194, 1997. PMID: 9542659
81. Sommardahl CS, Woychik RP, Sweeney WE, Avner ED, Wilkinson JE: Efficacy of taxol in the orpk mouse model of polycystic kidney disease. Pediatr Nephrol 11:728-733, 1997. PMID: 9438653
82. Davis ID, Oehlenschlager W, O'Riordan MA, Avner ED: Pediatric percutaneous renal biopsy: Should this procedure be performed in an outpatient setting? Pediatr Nephrol 12:96-100, 1998. PMID: 9543363
83. Orellana SA, Avner ED: Cell and molecular biology of kidney development. Sem Neph 18:233-243, 1998. PMID: 9613864
84. Davis ID, Bunchman TE, Grimm PC, Benfield MR, Briscoe DM, Harmon WH, Alexander SR, Avner ED: Pediatric renal transplantation: Indications and special considerations. A position paper from the Pediatric Committee of the American Society of Transplant Physicians. Pediatr Transplant 2:117-129, 1998. PMID: 10082443
85. Mucher G, Becker J, Knapp M, Buttner R, Moser M, Rudnik-Schoneborn S, Somlo S, Germino G, Onuchic L, Avner ED, Guay-Woodford L, Zerres K: Fine mapping of the autosomal recessive polycystic kidney disease locus (PKHD1) and the genes MCM, RDS, CKII-β, GSTA1 at 6p21.1-12. Genomics 48:40-45, 1998.
86. Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU. Morphological and functional characterization of a conditionally immortalized collecting tubule cell line. Am J Physiol Renal Physiol. 1998 Nov 01;275(5):F802-F811.
87. Brandt JR, Joseph MW, Fouser LS, Tarr PI, Zelikovic I, McDonald RA, Avner ED, McAfee NC, Watkins SL: Cholelithiasis following Escherichia coli 0157:H7-associated hemolytic uremic syndrome. Pediatr Nephrol 12:222-225, 1998. PMID: 9630042
88. Takacs-Jarret M, Sweeney WE, Avner ED, Cotton CU: Morphological and functional characterization of a conditionally immortalized collecting tubule cell line. Amer J Physiol 275: 802-811, 1998. PMID: 9815138
89. Murcia NS, Woychik RP, Avner ED: The molecular biology of polycystic kidney disease. Pediatr Nephrol 12:721-726, 1998. PMID: 9874315
90. Richards WG, Sweeney WE, Yoder BK, Wilkinson JE, Woychik RP, Avner ED: Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease. J Clin Invest 101:935-939, 1998. PMID: 9486961
91. Sweeney WE, Avner ED: Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease. Amer J Physiol 44: F387-F394, 1998. PMID: 9729511
92. Woychik RP, Klebig ML, Justice MJ, Magnuson TR, Avner ED: Functional genomics in the post-genome era. Mutation Research 400: 3-14, 1998. PMID: 9685569
93. Murcia NS, Sweeney WE, Avner ED: New insights into the molecular pathophysiology of polycystic kidney disease. Kidney Int 55:1187-1197, 1999. PMID: 10200981
94. Zerres K, Mucher G, Becker J, Steinkamm C, Rudnik-Schoneborn S, Heikkila P, Rapola J, Salonen R, Germino GG, Somlo S, Avner ED, Harman LA, Stockwin JM, Guay-Woodford LM: Prenatal diagnosis of autosomal recessive polycystic kidney disease (ARPKD): Molecular genetics, clinical experience and fetal morphology. Amer J Med Genet 76:137-144, 1998. PMID: 9511976
95. Brandt JR, Avner ED, Hickman RO, Watkins SL. Safety and efficacy of erythropoietin in children with chronic renal failure. Pediatr Nephrol 13: 143-147, 1999. PMID: 10229004
96. Cotton CU, Avner ED. PKD and CF: An interesting family provides insight into the molecular pathophysiology of polycystic kidney disease. Amer J Kid Dis 32: 1081-1083, 1998. PMID: 9856528
97. Avner ED, Woychik RP, Dell KM, Sweeney WE. Cellular pathophysiology of cystic kidney disease: Insight into future therapies. Inter J Dev Biol 43: 457-461, 1999. PMID: 10535324
98. Park JH, Dixit MP, Onuchic LF, Wu G, Goncharuk AN, Kneitz S, Santarina LB, Hayashi T, Avner ED, Guay-Woodford L, Zerres K, Germino GG, Somlo S. A 1 Mb BAC/PAC-based physical map of the autosomal recessive polycystic kidney disease gene (PKHD1) region on chromosome 6. Genomics 57: 249-255, 1999. PMID: 10198164
99. Sweeney WE, Futey L, Frost P, Avner ED. In vitro modulation of cyst formation by a novel tyrosine kinase inhibitor. Kidney Int 56: 406-413, 1999. PMID: 10432378
100. Avner ED. Glomerulosclerosis and hypoplasia - A common theme? Kidney Int 56:1962-1963, 1999. PMID: 10571808
101. Nakanishi K, Sweeney WE, Zerres K, Guay-Woodford LG, Avner ED. Proximal tubular cysts in fetal human autosomal recessive polycystic kidney disease. J Amer Soc Nephrol 11:760-763, 2000. PMID: 10752536
102. Nakanishi K, Sweeney WE, Avner ED. Polycystic kidney disease: Insights into future therapies. J Dev Nephrol: 8:3-9, 2000.
103. Sweeney WE, Chen Y, Nakanishi K, Frost P, Avner ED. Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor. Kidney Int 57:33-40, 2000. PMID: 10620185
104. Onuchic LF, Mrug M, Lakings AL, Muecher G, Becker J, Zerres K. Avner ED, Dixit M, Somlo S, Germino GG, Guay-Woodford LM. Genomic organization of the KIAA0057 gene that encodes a TRAM-like protein and its exclusion as a polycystic kidney and hepatic disease 1 (PKHD1) candidate gene. Mammalian Genome 10: 1175-1178, 1999. PMID: 10594243
105. Hofmann Y, Becker J, Wright F, Avner ED, Mrug M, Guay-Woodford LM, Somlo S, Zerres K, Germino GG, Onuchic LF. Genomic structure of the gene for the human P1 protein (MCM3) and its exclusion as a candidate for autosomal recessive polycystic kidney disease. Euro J Human Gen 8: 163-166 (2000). PMID: 10780780
106. Nakanishi K, Sweeney WE, Avner ED. Segment-specific c-ErbB2 expression in human autosomal recessive polycystic kidney disease. J Amer Soc Nephrol 12:379-384, 2001. PMID: 11158230
107. Nakanishi K, Gattone II V, Sweeney WE, Avner ED. Renal dysfunction but not cystic change is ameliorated by neonatal EGF in bpk mice. Pediatr Nephrol 16:48-50, 2001. PMID: 11198603
108. Nakanishi K, Sweeney WE, Dell KM, Cotton C, Avner ED. Role of CFTR in autosomal recessive polycystic kidney disease. J Amer Soc Nephrol 12:719-725, 2001. PMID: 11274233
109. Nakanishi K, Sweeney WE, Avner ED, Murcia NS. Expression of the Oak Ridge polycystic kidney (orpk) disease gene during kidney development and maturation. Pediatr Nephrol 16:219-226, 2001. PMID: 11322368
110. Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU. Generation and phenotype of cell lines derived from CF and non-CF mice that carry the H-2Kb-tsA58 transgene. Am J Physiol 280:C228-C236, 2001. PMID: 11158230
111. Davis ID, Dell KM, Sweeney WE, Avner ED: Can progression of autosomal dominant or autosomal recessive polycystic kidney disease be prevented? Seminars in Nephrology 21:430-440, 2001. PMID: 11559884
112. Avner ED: Childhood ADPKD - Answers and more questions. Kidney Int 59:1979-1980, 2001. PMID: 11318972
113. Nakanishi K, Sweeney WE Jr, Avner ED. Segment-specific c-ErbB2 expression in human autosomal recessive polycystic kidney disease. J Am Soc Nephrol. 2001 Feb;12(2):379-384.
114. Dell KM, Nemo R, Sweeney WE, Levin J, Frost P, Avner ED. A novel inhibitor of TNF-Alpha converting enzyme ameliorates polycystic kidney disease. Kidney Int 60:1240-1248, 2001. PMID: 11576338
115. Sweeney WE, Kusner L, Carlin CR, Chang S, Futey L, Cotton CU, Avner ED. Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD. Amer J Physiol 281:C1695-1705, 2001. PMID: 11600434
116. Onuchic LF, Mrug M, Hou X, Eggerman T, Bergmann C, Zerres K, Avner ED, Furu L, Somlo S, Nagasawa Y, Germino GG, Guay-Woodford LM. Refinement of the autosomal recessive polycystic kidney disease (PKHD1) interval and exclusion of an EF hand-containing gene as PKHD1 candidate gene. Amer J Med Genetics 110(4):346-352, 2002. PMID: 12116208
117. Onuchic LF, Furu L, Nagasawa Y, Hou X, Eggerman T, Ren Z, Bergmann C, Sanderek J, Esquivel E, Zeltner R, Rudnic-Schoneborn S, Mrug M, Sweeney W, Avner ED, Zerres K, Guay-Woodford LM, Somlo S, Germino GG. PKHD1, the polycystic kidney and hepatic disease 1 gene (PKHD1) encodes a novel large protein containing multiple IPT domains and PbH1 repeats. Amer J Human Genetics 70:1305-1317, 2002. PMID: 11898128
118. Nagasawa Y, Matthiesen S, Onuchic LF, Hou X, Bergmann C, Esquivel E, Senderek J, Ren Z, Zeltner R, Furu L, Avner ED, Moser M, Somlo S, Guay-Woodford L, Buttner R, Zerres K, Germino G. Identification and characterization of the human ARPKD gene. J Am Soc Nephrol 13:2246-2258, 2002.
119. Wisanuyotin S, Dell KM, Vogt BA, O'Riordan MA, Avner ED, Davis ID. Complications of peritoneal dialysis in children with Eagle-Barrett Syndrome. Ped Nephrol, 18:159-163, 2003. PMID: 12579407.
120. Drotar D, Avner ED. Critical choices in mentoring the next generation of academic pediatricians: Nine circles of hell or salvation? J of Pediatrics 142, 1-2, 2003. PMID: 12520243.
121. Torres V, Sweeney WE, Qian Q, Harris PC, Frost P, Avner ED: EGF receptor tyrosine kinase inhibition attenuates PKD development in Han:SPRD rats. Kidney Inter 64:1573-1579, 2003. PMID: 14531789.
122. Davis ID, Ho M, Hupertz V, Avner ED. Survival of childhood polycystic kidney disease following renal transplantation: The impact of advanced hepatobiliary disease. Ped Transplant 7:364-369, 2003. PMID: 14738296.
123. Bayazit A, Vogt BA, Dell KM, Davis ID, Noyan A, Anarat A, Avner ED, Erhard P, Weiss M. Effect of the peritoneal dialysis prescription on pentosidine in children. Ped Nephrol 18:1049-1054, 2003. PMID: 12898376.
124. Sweeney WE, Hamahira K, Sweeney J, Garcia-Gattell M, Frost P, Avner ED. Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability. Kidney Inter 64:1310-1319, 2003. PMID: 12969149.
125. Grimm DH, Cai Y, Chauvet V, Rajendran V, Avner ED, Sweeney W, Somlo S, Caplan MJ. Polycystin-1 localization is a function of polycystin-2 expression in mammalian cells. J Biol Chem 278:36786-36793, 2003. PMID: 12840011.
126. Furu L, Onuchic LF, Gharavi A, Hou X, Esquivel E, Nagasawa Y, Bergmann C, Senderek J, Avner ED, Zerres K, Germino GG, Guay-Woodford LM, Somlo S: Milder presentation of recessive polycystic kidney disease requires presence of amino acid substitution mutations. J Am Soc Nephrol 14:2004-2014, 2003. PMID: 12874454.
127. Dell KM, Nemo R, Sweeney WE, Avner ED. EGF-Related growth factors in the pathogenesis of murine ARPKD. Kidney Inter 65:2018-2029, 2004. PMID: 15496147.
128. Torres VE, Sweeney WE, Wang X, Qian Q, Harris PC, Frost P, Avner, ED. Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition is not protective in PCK Rats. Kidney Inter 66(5):1766-73, 2004. PMID: 15496147.
129. Consugar M, Anderson SA, Rossetti S, Pankratz VS, Ward CJ, Torra R, Coto E, El-Youssef M, Kantarci S, Utsch B, Hildebrandt F, Sweeney WE, Avner ED, Torres VE, Cunningham JM, Harris.PC. Haplotype analysis improves molecular diagnostics of autosomal recessive polycystic kidney disease (ARPKD). Am J Kidney Dis 45(1):77-87, 2005. PMID: 15696446.
130. Sweeney WE and Avner ED. Molecular and Cellular Pathophysiology of Autosomal Recessive Polycystic Kidney Disease. Cell Tissue Res 326:671-685, 2006. PMID: 16767405.
131. Gunay-Aygun M, Avner ED et al. First Office of Rare Disorders (ORD)-National Institutes of Health (NIH) Workshop on Autosomal Recessive Polycystic Kidney Disease and Congenital Hepatic Fibrosis (ARPKD/CHF) Summary Statement. J Pediatr. 149 (2):159-64, 2006. PMID: 16887426.
132. Sweeney WE, Avner ED. Renal cystic disease: new insights for the clinician. Pediatr Clin North Am 53:889-909, 2006. PMID: 17027616
133. Sweeney WE, von Vigier RO, Frost P, Avner ED. Src inhibition ameliorates autosomal recessive polycystic kidney disease in the BPK murine model. J Am Soc Nephrol. 19:1331-1341, 2008. PMCID: PMC2440293.
134. Park F, Sweeney WE, Jia G, Roman RJ, Avner ED. 20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease. J Am Soc Nephrol. 19:1929-1940, 2008. PMCID: PMC2551562.
135. Park F, Sweeney WE Jr, Jia G, Akbulut T, Mueller B, Falck JR, Birudaraju S, Roman RJ, Avner ED. Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD. Am J Physiol Renal Physiol. 2009 Mar;296(3):F575-82. PMCID: PMC2660198
136. Park, F, Sweeney WE, Guanggfu J, Akbulut T, Mueller B, Falck J, Birudaraju S, Roman R, Avner ED. Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD. Amer J Physiol Renal. 296:575-582, 2009. PMCID: PMC2660198.
137. Akbulut T, Regner KR, Roman RJ, Avner ED, Falck JR, Park F. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism. Am J Physiol Renal Physiol. 2009 Sep;297(3):F662-70. PMCID: PMC2739708
138. Dell KM, Avner ED. Polycystic kidney disease, autosomal recessive. In: Pagon RA, Bird TC, Dolan CR, Stephens K, editors GeneReviews. [Internet] 2009. PMID: 20301501.
139. Lau EC, Janson MM, Roesler MR, Avner ED, Strawn EY, Bick DP. Birth of a healthy infant following preimplantation PKHD1 haplotyping for autosomal recessive polycystic kidney disease using multiple displacement amplification. J Assist Reprod Genet. 2010 Jul;27(7):397-407. PMCID: PMC2922704
140. Sweeney WE, Avner ED. Diagnosis and management of childhood polycystic kidney disease. Pediatr Nephrol. 26 (5): 675-692.2011. PMID 21046169.
141. Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE, Park F. Loss of activator of G protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents. FASE J. 2011 March 7. [epub ahead of print]. PMID 21343176.
142. Liu W, Fan LX, Zhou X, Sweeney WE Jr, Avner ED, Li X. HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells. PLoS One. 2012;7(11):e49418. PMCID: PMC3496684
143. O'Meara CC, Hoffman M, Sweeney WE Jr, Tsaih SW, Xiao B, Jacob HJ, Avner ED, Moreno C. Role of genetic modifiers in an orthologous rat model of ARPKD. Physiol Genomics. 2012 Aug 01;44(15):741-53. PMCID: PMC3774585
144. McDonald RA, Avner ED. Inherited polycystic kidney disease in children. Semin Nephrol. 1991 Nov;11(6):632-42.
145. Avner ED. Polypeptide growth factors and the kidney: a developmental perspective. Pediatr Nephrol. 1990 Jul;4(4):345-53.
146. Morris SM Jr, Kepka DM, Sweeney WE Jr, Avner ED. Abundance of mRNAs encoding urea cycle enzymes in fetal and neonatal mouse liver. Arch Biochem Biophys. 1989 Feb 15;269(1):175-80.
147. Avner ED, Sweeney WE Jr, Ellis D. In vitro modulation of tubular cyst regression in murine polycystic kidney disease. Kidney Int. 1989 Dec;36(6):960-8.
148. Ellis D, Coonrod BA, Dorman JS, Kelsey SF, Becker DJ, Avner ED, Orchard TJ. Choice of urine sample predictive of microalbuminuria in patients with insulin-dependent diabetes mellitus. Am J Kidney Dis. 1989 Apr;13(4):321-8.
149. Ellis D, Sothi TD, Avner ED. Glucocorticoids modulate renal glucocorticoid receptors and Na-K ATPase activity. Kidney Int. 1987 Oct;32(4):464-71.
150. Ellis D, Sothi TD, Curthoys NP, Ballou B, Avner ED. Regulation of glucocorticoid receptors and Na-K ATPase activity by hydrocortisone in proximal tubular epithelial cells. In Vitro Cell Dev Biol. 1988 Aug;24(8):811-6.
151. Curto KA, Sweeney WE, Avner ED, Piesco NP, Curthoys NP. Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney. J Histochem Cytochem. 1988 Feb;36(2):159-66.
152. Avner ED, Sweeney WE Jr, Young MC, Ellis D. Congenital murine polycystic kidney disease. II. Pathogenesis of tubular cyst formation. Pediatr Nephrol. 1988 Apr;2(2):210-8.
153. Avner ED, Sweeney WE Jr, Piesco NP, Ellis D. Triiodothyronine-induced cyst formation in metanephric organ culture: the role of increased Na-K-adenosine triphosphatase activity. J Lab Clin Med. 1987 Apr;109(4):441-53.
154. Osorio AM, Thun MJ, Novak RF, Van Cura EJ, Avner ED. Silica and glomerulonephritis: case report and review of the literature. Am J Kidney Dis. 1987 Mar;9(3):224-30.
155. Avner ED, Sweeney WE Jr, Finegold DN, Piesco NP, Ellis D. Sodium-potassium ATPase activity mediates cyst formation in metanephric organ culture. Kidney Int. 1985 Sep;28(3):447-55.
156. Avner ED, Piesco NP, Sweeney WE Jr, Ellis D. Renal epithelial development in organotypic culture. Pediatr Nephrol. 1988 Jan;2(1):92-9.
157. Avner ED, Studnicki FE, Young MC, Sweeney WE Jr, Piesco NP, Ellis D, Fettermann GH. Congenital murine polycystic kidney disease. I. The ontogeny of tubular cyst formation. Pediatr Nephrol. 1987 Oct;1(4):587-96.
158. Avner ED. Renal cystic disease. Insights from recent experimental investigations. Nephron. 1988;48(2):89-93.
159. Ellis D, Avner ED, Starzl TE. Renal failure in children with hepatic failure undergoing liver transplantation. J Pediatr. 1986 Mar;108(3):393-8. PMCID: PMC2976655
160. Ellis D, Avner ED. Renal failure and dialysis therapy in children with hepatic failure in the perioperative period of orthotopic liver transplantation. Clin Nephrol. 1986 Jun;25(6):295-303.
161. Ellis D, Tran SD, Eagon PK, Avner ED. Reversible inhibition of cytosolic glucocorticoid receptors by mercurial agents. Application in the measurement of total and unoccupied receptors. J Recept Res. 1987;7(5):761-74.
162. Avner ED, Sweeney WE Jr, Piesco NP, Ellis D. Growth factor requirements of organogenesis in serum-free metanephric organ culture. In Vitro Cell Dev Biol. 1985 May;21(5):297-304.
163. Ellis D, Avner ED, Rosenthal JT, Taylor RJ, Young LW, Palumbi MA, Hakala TR. Renal function and somatic growth in pediatric cadaveric renal transplantation with cyclosporine-prednisone immunosuppression. Am J Dis Child. 1985 Nov;139(11):1161-7.
164. Avner ED, Sweeney WE Jr, Piesco NP, Ellis D. Regression of genetically determined polycystic kidney disease in murine organ culture. Experientia. 1986 Jan 15;42(1):77-80.
165. Ellis D, Avner ED, Kurs-Lasky M, Richards M, Becker DJ. Effects of improved glycemic control on microalbuminuria in adolescents with insulin-dependent diabetes mellitus. Int J Pediatr Nephrol. 1986 Jan-Mar;7(1):31-8.
166. Avner ED, Ingelfinger JR, Herrin JT, Link DA, Marcus E, Tolkoff-Rubin NE, Russell-Getz L, Rubin RH. Single-dose amoxicillin therapy of uncomplicated pediatric urinary tract infections. J Pediatr. 1983 Apr;102(4):623-7.
167. Ellis D, Avner ED, Transue D, Yunis EJ, Drash AL, Becker DJ. Diabetic nephropathy in adolescence: appearance during improved glycemic control. Pediatrics. 1983 May;71(5):824-9.
168. Avner ED, Sweeney WE Jr, Ellis D. Cyst formation in metanephric organ culture induced by cis-dichlorodiammineplatinum (II). Experientia. 1983 Jan 15;39(1):74-6.
169. Avner ED, Piesco NP, Sweeney WE Jr, Studnicki FM, Fetterman GH, Ellis D. Hydrocortisone-induced cystic metanephric maldevelopment in serum-free organ culture. Lab Invest. 1984 Feb;50(2):208-18.
170. Ellis D, Turocy JF, Sweeney WE Jr, Avner ED. Partial characterization and ontogeny of renal cytosolic glucocorticoid receptors in mouse kidney. J Steroid Biochem. 1986 May;24(5):997-1003.
171. Avner ED, Sweeney WE Jr, Piesco NP, Ellis D. A new model of glucocorticoid-induced metanephric maldevelopment. Experientia. 1984 May 15;40(5):489-90.
172. Avner ED, Jaffe R, Temple T, Ellis D, Chung AE. Development of renal basement membrane glycoproteins in metanephric organ culture. Lab Invest. 1983 Mar;48(3):263-8.
173. Avner ED, Ellis D, Jaffe R. Veno-occlusive disease of the liver associated with cysteamine treatment of nephropathic cystinosis. J Pediatr. 1983 May;102(5):793-6.
174. Avner ED, Villee DB, Schneeberger EE, Grupe WE. An organ culture model for the study of metanephric development. J Urol. 1983 Mar;129(3):660-4.
175. Avner ED, Harmon WE, Grupe WE, Ingelfinger JR, Eraklis AJ, Levey RH. Mortality of chronic hemodialysis and renal transplantation in pediatric end-stage renal disease. Pediatrics. 1981 Mar;67(3):412-6.
176. Avner ED, Ellis D, Jaffe R, Bowen A. Neonatal radiocontrast nephropathy simulating infantile polycystic kidney disease. J Pediatr. 1982 Jan;100(1):85-7.
177. Avner ED. Gene time for polycystic kidney disease. Lancet. 1994 Sep 24;344(8926):833-4.
178. Johnson JA, Grande JP, Roche PC, Sweeney WE Jr, Avner ED, Kumar R. 1 alpha, 25-dihydroxyvitamin D3 receptor ontogenesis in fetal renal development. Am J Physiol. 1995 Sep;269(3 Pt 2):F419-28.
179. Orellana SA, Avner ED. Cystic maldevelopment of the kidney. Semin Nephrol. 1995 Jul;15(4):341-52.
180. Nauta J, Sweeney WE, Rutledge JC, Avner ED. Biliary epithelial cells from mice with congenital polycystic kidney disease are hyperresponsive to epidermal growth factor. Pediatr Res. 1995 Jun;37(6):755-63.
181. Foreman JW, Benson LL, Wellons M, Avner ED, Sweeney W, Nissim I, Nissim I. Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester model of cystinosis. J Am Soc Nephrol. 1995 Aug;6(2):269-72.
182. Pugh JL, Sweeney WE Jr, Avner ED. Tyrosine kinase activity of the EGF receptor in murine metanephric organ culture. Kidney Int. 1995 Mar;47(3):774-81.
183. Sliman GA, Winters WD, Shaw DW, Avner ED. Hypercalciuria and nephrocalcinosis in the oculocerebrorenal syndrome. J Urol. 1995 Apr;153(4):1244-6.
184. Fouser L, Avner ED. Normal and abnormal nephrogenesis. Am J Kidney Dis. 1993 Jan;21(1):64-70.
185. Ozawa Y, Nauta J, Sweeney WE, Avner ED. A new murine model of autosomal recessive polycystic kidney disease. Nihon Jinzo Gakkai Shi. 1993 Apr;35(4):349-54.
186. Nauta J, Ozawa Y, Sweeney WE Jr, Rutledge JC, Avner ED. Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease. Pediatr Nephrol. 1993 Apr;7(2):163-72.
187. Jabs K, Sullivan EK, Avner ED, Harmon WE. Alternate-day steroid dosing improves growth without adversely affecting graft survival or long-term graft function. A report of the North American Pediatric Renal Transplant Cooperative Study. Transplantation. 1996 Jan 15;61(1):31-6.
188. Becker N, Avner ED. Congenital nephropathies and uropathies. Pediatr Clin North Am. 1995 Dec;42(6):1319-41.
189. Avner ED. Epithelial polarity and differentiation in polycystic kidney disease. J Cell Sci Suppl. 1993;17:217-22.
190. Avner ED. Renal developmental diseases. Semin Nephrol. 1993 Sep;13(5):427-35.
191. Moyer JH, Lee-Tischler MJ, Kwon HY, Schrick JJ, Avner ED, Sweeney WE, Godfrey VL, Cacheiro NL, Wilkinson JE, Woychik RP. Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. Science. 1994 May 27;264(5163):1329-33.
192. Brandt JR, Fouser LS, Watkins SL, Zelikovic I, Tarr PI, Nazar-Stewart V, Avner ED. Escherichia coli O 157:H7-associated hemolytic-uremic syndrome after ingestion of contaminated hamburgers. J Pediatr. 1994 Oct;125(4):519-26.
193. Guay-Woodford LM, Muecher G, Hopkins SD, Avner ED, Germino GG, Guillot AP, Herrin J, Holleman R, Irons DA, Primack W. The severe perinatal form of autosomal recessive polycystic kidney disease maps to chromosome 6p21.1-p12: implications for genetic counseling. Am J Hum Genet. 1995 May;56(5):1101-7. PMCID: PMC1801440
194. Avner ED, Chavers B, Sullivan EK, Tejani A. Renal transplantation and chronic dialysis in children and adolescents: the 1993 annual report of the North American Pediatric Renal Transplant Cooperative Study. Pediatr Nephrol. 1995 Feb;9(1):61-73.
195. Avner ED. Clinical disorders of water metabolism: hyponatremia and hypernatremia. Pediatr Ann. 1995 Jan;24(1):23-30.
196. Orellana SA, Sweeney WE, Neff CD, Avner ED. Epidermal growth factor receptor expression is abnormal in murine polycystic kidney. Kidney Int. 1995 Feb;47(2):490-9.
197. Becker N, Rutledge JC, Avner ED. Clinical quiz. Differential diagnosis of a patient with Wegener's granulomatosis. Pediatr Nephrol. 1995 Dec;9(6):785-7.
198. Holleman R, Avner ED. Clinical quiz. Differential diagnosis of a patient with hypertension. Pediatr Nephrol. 1995 Dec;9(6):783-4.
199. Brandt JR, Joseph MW, Fouser LS, Tarr PI, Zelikovic I, McDonald RA, Avner ED, McAfee NG, Watkins SL. Cholelithiasis following Escherichia coli O157:H7-associated hemolytic uremic syndrome. Pediatr Nephrol. 1998 Apr;12(3):222-5.
200. Orellana SA, Avner ED. Cell and molecular biology of kidney development. Semin Nephrol. 1998 May;18(3):233-43.
201. Murcia NS, Sweeney WE Jr, Avner ED. New insights into the molecular pathophysiology of polycystic kidney disease. Kidney Int. 1999 Apr;55(4):1187-97.
202. Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU. Morphological and functional characterization of a conditionally immortalized collecting tubule cell line. Am J Physiol. 1998 11;275(5):F802-11.
203. Orellana SA, Neff CD, Sweeney WE, Avner ED. Novel Madin Darby canine kidney cell clones exhibit unique phenotypes in response to morphogens. In Vitro Cell Dev Biol Anim. 1996 Jun;32(6):329-39.
204. Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP. Functional correction of renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA. Kidney Int. 1996 Oct;50(4):1240-8.
205. Guay-Woodford LM, Bryda EC, Christine B, Lindsey JR, Collier WR, Avner ED, D'Eustachio P, Flaherty L. Evidence that two phenotypically distinct mouse PKD mutations, bpk and jcpk, are allelic. Kidney Int. 1996 Oct;50(4):1158-65.
206. Onuchic LF, Mrug M, Lakings AL, Muecher G, Becker J, Zerres K, Avner ED, Dixit M, Somlo S, Germino GG, Guay-Woodford LM. Genomic organization of the KIAA0057 gene that encodes a TRAM-like protein and its exclusion as a polycystic kidney and hepatic disease 1 (PKHD1) candidate gene. Mamm Genome. 1999 Dec;10(12):1175-8.
207. Park JH, Dixit MP, Onuchic LF, Wu G, Goncharuk AN, Kneitz S, Santarina LB, Hayashi T, Avner ED, Guay-Woodford L, Zerres K, Germino GG, Somlo S. A 1-Mb BAC/PAC-based physical map of the autosomal recessive polycystic kidney disease gene (PKHD1) region on chromosome 6. Genomics. 1999 Apr 15;57(2):249-55.
208. Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP. Differential rescue of the renal and hepatic disease in an autosomal recessive polycystic kidney disease mouse mutant. A new model to study the liver lesion. Am J Pathol. 1997 Jun;150(6):2231-41. PMCID: PMC1858312
209. Lens XM, Onuchic LF, Wu G, Hayashi T, Daoust M, Mochizuki T, Santarina LB, Stockwin JM, Mücher G, Becker J, Sweeny WE Jr, Avner ED, Guay-Woodford L, Zerres K, Somlo S, Germino GG. An integrated genetic and physical map of the autosomal recessive polycystic kidney disease region. Genomics. 1997 May 01;41(3):463-6.
210. Sommardahl CS, Woychik RP, Sweeney WE, Avner ED, Wilkinson JE. Efficacy of taxol in the orpk mouse model of polycystic kidney disease. Pediatr Nephrol. 1997 Dec;11(6):728-33.
211. Becker N, Brandt JR, Sutherland TA, Avner ED, Watkins SL. Improved outcome of young children on nightly automated peritoneal dialysis. Pediatr Nephrol. 1997 Dec;11(6):676-9.
212. Richards WG, Sweeney WE, Yoder BK, Wilkinson JE, Woychik RP, Avner ED. Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease. J Clin Invest. 1998 Mar 01;101(5):935-9. PMCID: PMC508642
213. Zerres K, Mücher G, Becker J, Steinkamm C, Rudnik-Schöneborn S, Heikkilä P, Rapola J, Salonen R, Germino GG, Onuchic L, Somlo S, Avner ED, Harman LA, Stockwin JM, Guay-Woodford LM. Prenatal diagnosis of autosomal recessive polycystic kidney disease (ARPKD): molecular genetics, clinical experience, and fetal morphology. Am J Med Genet. 1998 Mar 05;76(2):137-44.
214. Sweeney WE Jr, Avner ED. The role of hepatocyte growth factor (HGF) at progressive stages of metanephric development. In Vitro Cell Dev Biol Anim. 1998 Feb;34(2):189-94.
215. Davis ID, Oehlenschlager W, O'Riordan MA, Avner ED. Pediatric renal biopsy: should this procedure be performed in an outpatient setting? Pediatr Nephrol. 1998 Feb;12(2):96-100.
216. Sweeney WE Jr, Avner ED. Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease. Am J Physiol. 1998 09;275(3):F387-94.
217. Woychik RP, Klebig ML, Justice MJ, Magnuson TR, Avner ED. Functional genomics in the post-genome era. Mutat Res. 1998 May 25;400(1-2):3-14.
218. Cotton CU, Avner ED. PKD and CF: an interesting family provides insight into the molecular pathophysiology of polycystic kidney disease. Am J Kidney Dis. 1998 Dec;32(6):1081-3.
219. Murcia NS, Woychik RP, Avner ED. The molecular biology of polycystic kidney disease. Pediatr Nephrol. 1998 Nov;12(9):721-6.
220. Davis ID, Bunchman TE, Grimm PC, Benfield MR, Briscoe DM, Harmon WE, Alexander SR, Avner ED. Pediatric renal transplantation: indications and special considerations. A position paper from the Pediatric Committee of the American Society of Transplant Physicians. Pediatr Transplant. 1998 May;2(2):117-29.
221. Brandt JR, Avner ED, Hickman RO, Watkins SL. Safety and efficacy of erythropoietin in children with chronic renal failure. Pediatr Nephrol. 1999 Feb;13(2):143-7.
222. Avner ED, Woychik RP, Dell KM, Sweeney WE. Cellular pathophysiology of cystic kidney disease: insight into future therapies. Int J Dev Biol. 1999;43(5):457-61.
223. Sweeney WE, Futey L, Frost P, Avner ED. In vitro modulation of cyst formation by a novel tyrosine kinase inhibitor. Kidney Int. 1999 Aug;56(2):406-13.
224. Avner ED. Glomerulosclerosis and hypoplasia--a common theme? Kidney Int. 1999 Nov;56(5):1962-3.
225. Sweeney WE, Chen Y, Nakanishi K, Frost P, Avner ED. Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor. Kidney Int. 2000 Jan;57(1):33-40.
226. Hofmann Y, Becker J, Wright F, Avner ED, Mrug M, Guay-Woodford LM, Somlo S, Zerres K, Germino GG, Onuchic LF. Genomic structure of the gene for the human P1 protein (MCM3) and its exclusion as a candidate for autosomal recessive polycystic kidney disease. Eur J Hum Genet. 2000 Mar;8(3):163-6.
227. Nakanishi K, Sweeney WE Jr, Zerres K, Guay-Woodford LM, Avner ED. Proximal tubular cysts in fetal human autosomal recessive polycystic kidney disease. J Am Soc Nephrol. 2000 Apr;11(4):760-763.
228. Nakanishi K, Gattone VH 2nd, Sweeney WE, Avner ED. Renal dysfunction but not cystic change is ameliorated by neonatal epidermal growth factor in bpk mice. Pediatr Nephrol. 2001 Jan;16(1):45-50.
229. Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU. Generation and phenotype of cell lines derived from CF and non-CF mice that carry the H-2K(b)-tsA58 transgene. Am J Physiol Cell Physiol. 2001 Jan;280(1):C228-36.
230. Nakanishi K, Sweeney WE Jr, Avner ED, Murcia NS. Expression of the orpk disease gene during kidney development and maturation. Pediatr Nephrol. 2001 Mar;16(3):219-26.
231. Avner ED. Childhood ADPKD: answers and more questions. Kidney Int. 2001 May;59(5):1979-80.
232. Nakanishi K, Sweeney WE Jr, Macrae Dell K, Cotton CU, Avner ED. Role of CFTR in autosomal recessive polycystic kidney disease. J Am Soc Nephrol. 2001 Apr;12(4):719-725.
233. Dell KM, Nemo R, Sweeney WE Jr, Levin JI, Frost P, Avner ED. A novel inhibitor of tumor necrosis factor-alpha converting enzyme ameliorates polycystic kidney disease. Kidney Int. 2001 Oct;60(4):1240-8.
234. Davis ID, MacRae Dell K, Sweeney WE, Avner ED. Can progression of autosomal dominant or autosomal recessive polycystic kidney disease be prevented? Semin Nephrol. 2001 Sep;21(5):430-40.
235. Sweeney WE Jr, Kusner L, Carlin CR, Chang S, Futey L, Cotton CU, Dell KM, Avner ED. Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD. Am J Physiol Cell Physiol. 2001 Nov;281(5):C1695-705.
236. Onuchic LF, Furu L, Nagasawa Y, Hou X, Eggermann T, Ren Z, Bergmann C, Senderek J, Esquivel E, Zeltner R, Rudnik-Schöneborn S, Mrug M, Sweeney W, Avner ED, Zerres K, Guay-Woodford LM, Somlo S, Germino GG. PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats. Am J Hum Genet. 2002 May;70(5):1305-17. PMCID: PMC447605
237. Onuchic LF, Mrug M, Hou X, Eggermann T, Bergmann C, Zerres K, Avner ED, Furu L, Somlo S, Nagasawa Y, Germino GG, Guay-Woodford LM. Refinement of the autosomal recessive polycystic kidney disease (PKHD1) interval and exclusion of an EF hand-containing gene as a PKHD1 candidate gene. Am J Med Genet. 2002 Jul 15;110(4):346-52.
238. Torres VE, Sweeney WE Jr, Wang X, Qian Q, Harris PC, Frost P, Avner ED. EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats. Kidney Int. 2003 Nov;64(5):1573-9.
239. Sweeney WE Jr, Hamahira K, Sweeney J, Garcia-Gatrell M, Frost P, Avner ED. Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability. Kidney Int. 2003 Oct;64(4):1310-9.
240. Wisanuyotin S, Dell KM, Vogt BA, O'Riordan MA, Avner ED, Davis ID. Complications of peritoneal dialysis in children with Eagle-Barrett syndrome. Pediatr Nephrol. 2003 Feb;18(2):159-63.
241. Drotar D, Avner ED. Critical choices in mentoring the next generation of academic pediatricians: nine circles of hell or salvation? J Pediatr. 2003 Jan;142(1):1-2.
242. Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ. Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. J Biol Chem. 2003 Sep 19;278(38):36786-93.
243. Bayazit AK, Vogt BA, Dell KM, Davis ID, Noyan A, Anarat A, Avner ED, Erhard P, Weiss MF. Effect of the peritoneal dialysis prescription on pentosidine in children. Pediatr Nephrol. 2003 Oct;18(10):1049-54.
244. MacRae Dell K, Nemo R, Sweeney WE Jr, Avner ED. EGF-related growth factors in the pathogenesis of murine ARPKD. Kidney Int. 2004 Jun;65(6):2018-29.
245. Torres VE, Sweeney WE Jr, Wang X, Qian Q, Harris PC, Frost P, Avner ED. Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats. Kidney Int. 2004 Nov;66(5):1766-73.
246. Consugar MB, Anderson SA, Rossetti S, Pankratz VS, Ward CJ, Torra R, Coto E, El-Youssef M, Kantarci S, Utsch B, Hildebrandt F, Sweeney WE, Avner ED, Torres VE, Cunningham JM, Harris PC. Haplotype analysis improves molecular diagnostics of autosomal recessive polycystic kidney disease. Am J Kidney Dis. 2005 Jan;45(1):77-87.
247. Gunay-Aygun M, Avner ED, Bacallao RL, Choyke PL, Flynn JT, Germino GG, Guay-Woodford L, Harris P, Heller T, Ingelfinger J, Kaskel F, Kleta R, LaRusso NF, Mohan P, Pazour GJ, Shneider BL, Torres VE, Wilson P, Zak C, Zhou J, Gahl WA. Autosomal recessive polycystic kidney disease and congenital hepatic fibrosis: summary statement of a first National Institutes of Health/Office of Rare Diseases conference. J Pediatr. 2006 Aug;149(2):159-64. PMCID: PMC2918414
248. Sweeney WE Jr, Avner ED. Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD). Cell Tissue Res. 2006 Dec;326(3):671-85.
249. Avner ED, Sweeney WE Jr. Renal cystic disease: new insights for the clinician. Pediatr Clin North Am. 2006 Oct;53(5):889-909, ix.
250. Sweeney WE Jr, von Vigier RO, Frost P, Avner ED. Src inhibition ameliorates polycystic kidney disease. J Am Soc Nephrol. 2008 Jul;19(7):1331-41. PMCID: PMC2440293
251. Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE Jr, Park F. Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents. FASEB J. 2011 Jun;25(6):1844-55. PMCID: PMC3101034
252. Avner ED, McDonough AA, Sweeney WE Jr. Transport, cilia, and PKD: must we in (cyst) on interrelationships? Focus on "Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease". Am J Physiol Cell Physiol. 2012 May 15;302(10):C1434-5. PMCID: PMC3362002
253. Liu W, Fan LX, Zhou X, Sweeney WE Jr, Avner ED, Li X. HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells. PLoS One. 2012;7(11):e49418. PMCID: PMC3496684
254. Kwon M, Pavlov TS, Nozu K, Rasmussen SA, Ilatovskaya DV, Lerch-Gaggl A, North LM, Kim H, Qian F, Sweeney WE Jr, Avner ED, Blumer JB, Staruschenko A, Park F. G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21462-7. PMCID: PMC3535663
255. Telega G, Cronin D, Avner ED. New approaches to the autosomal recessive polycystic kidney disease patient with dual kidney-liver complications. Pediatr Transplant. 2013 Jun;17(4):328-35. PMCID: PMC3663883
256. Zhou X, Fan LX, Sweeney WE Jr, Denu JM, Avner ED, Li X. Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease. J Clin Invest. 2013 Jul;123(7):3084-98. PMCID: PMC4101988
257. Fan LX, Zhou X, Sweeney WE Jr, Wallace DP, Avner ED, Grantham JJ, Li X. Smac-mimetic-induced epithelial cell death reduces the growth of renal cysts. J Am Soc Nephrol. 2013 Dec;24(12):2010-22. PMCID: PMC3839552
258. Sweeney WE Jr, Avner ED. Pathophysiology of childhood polycystic kidney diseases: new insights into disease-specific therapy. Pediatr Res. 2014 Jan;75(1-2):148-57. PMCID: PMC3953890
259. Sweeney WE Jr, Avner ED. Emerging Therapies for Childhood Polycystic Kidney Disease. Front Pediatr. 2017;5:77. PMCID: PMC5395658
260. Sweeney WE, Frost P, Avner ED. Tesevatinib ameliorates progression of polycystic kidney disease in rodent models of autosomal recessive polycystic kidney disease. World J Nephrol. 2017 Jul 06;6(4):188-200. PMCID: PMC5500456
261. Patil A, Sweeney WE Jr, Pan CG, Avner ED. Unique interstitial miRNA signature drives fibrosis in a murine model of autosomal dominant polycystic kidney disease. World J Nephrol. 2018 09 07;7(5):108-116. PMCID: PMC6134266
262. Avner ED, Satz J, Plotkin SA. Letter: Hypoglycorrachia in young infants with viral meningitis. J Pediatr. 1975 Nov;87(5):833-4.
263. Avner ED, Ellis D, Temple T, Jaffe R. Metanephric development in serum-free organ culture. In Vitro. 1982 Aug;18(8):675-82.
264. Davis ID, Ho M, Hupertz V, Avner ED. Survival of childhood polycystic kidney disease following renal transplantation: the impact of advanced hepatobiliary disease. Pediatr Transplant. 2003 Oct;7(5):364-9.
265. Park F, Sweeney WE, Jia G, Roman RJ, Avner ED. 20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease. J Am Soc Nephrol. 2008 Oct;19(10):1929-39. PMCID: PMC2551562
266. Sweeney WE Jr, Avner ED. Diagnosis and management of childhood polycystic kidney disease. Pediatr Nephrol. 2011 May;26(5):675-92.
267. Levy H, Jia S, Pan A, Zhang X, Kaldunski M, Nugent ML, Reske M, Feliciano RA, Quintero D, Renda MM, Woods KJ, Murkowski K, Johnson K, Verbsky J, Dasu T, Ideozu JE, McColley S, Quasney MW, Dahmer MK, Avner E, Farrell PM, Cannon CL, Jacob H, Simpson PM, Hessner MJ. Identification of molecular signatures of cystic fibrosis disease status with plasma-based functional genomics. Physiol Genomics. 2019 01 01;51(1):27-41. PMCID: PMC6383551
268. Nozu K, Sweeney WEJ, Avner ED. Fìbrocystin/polyductin and pathophysiology of autosomal recessive polycystic kidney disease Polycystic Kidney Disease: From Bench to Bedside. March 01, 2015:43-58.
269. Sweeney WE, Gunay-Aygun M, Patil A, Avner ED. Childhood polycystic kidney disease Pediatric Nephrology, Seventh Edition. 1 January 2015:1103-1153.
270. Avner ED, Harmon WE, Niaudet P, Yoshikawa N, Emma F, Goldstein SL. Preface Pediatric Nephrology, Seventh Edition. 1 January 2015:v-viii.
271. Avner ED, Harmon WE, Niaudet P, Yoshikawa N, Emma F, Goldstein SL. Pediatric nephrology, seventh edition Pediatric Nephrology, Seventh Edition. 1 January 2015:1-2730.
272. Park F, Sweeney WE, Jia G, Akbulut T, Mueller B, Falck JR, Birudaraju S, Roman RJ, Avner ED. Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD (American Journal of Physiology - Renal Physiology (2009) 296, (F575-F582) DOI: 10.1152/ajprenal.90705.2008) American Journal of Physiology - Renal Physiology. October 2009;297(4).
273. Avner ED, Kliegman RM. Preface Pediatric Clinics of North America. October 2006;53(5).
274. Avner ED, Kliegman RM. Preface Pediatric Clinics of North America. August 2006;53(4).
275. Sweeney WE, Avner ED. Embryogenesis and Anatomic Development of the Kidney Fetal and Neonatal Physiology: Third Edition. December 01, 2003;2-2:1223-1229.
276. Furu L, Onuchic LF, Gharavi A, Hou X, Esquivel EL, Nagasawa Y, Bergmann C, Senderek J, Avner E, Zerres K, Germino GG, Guay-Woodford LM, Somlo S. Milder presentation of recessive polycystic kidney disease requires presence of amino acid substitution mutations. J Am Soc Nephrol. 2003 Aug;14(8):2004-14.
277. Nagasawa Y, Matthiesen S, Onuchic LF, Hou X, Bergmann C, Esquivel E, Senderek J, Ren Z, Zeltner R, Furu L, Avner E, Moser M, Somlo S, Guay-Woodford L, Büttner R, Zerres K, Germino GG. Identification and characterization of Pkhd1, the mouse orthologue of the human ARPKD gene. J Am Soc Nephrol. 2002 Sep;13(9):2246-58.
278. Avner ED. Cellular Pathophysiology of Polycystic Kidney Disease: Insights into Future Therapy Japanese Journal of Nephrology. January 1999;41(3):233-235.
279. Avner ED. Genetic disease of the kidney: Introduction Seminars in Nephrology. 1999;19(4):311.
280. Mücher G, Becker J, Knapp M, Büttner R, Moser M, Rudnik-Schöneborn S, Somlo S, Germino G, Onuchic L, Avner E, Guay-Woodford L, Zerres K. Fine mapping of the autosomal recessive polycystic kidney disease locus (PKHD1) and the genes MUT, RDS, CSNK2 beta, and GSTA1 at 6p21.1-p12. Genomics. 1998 Feb 15;48(1):40-5.
281. Woychik RP, Klebig ML, Justice MJ, Magnuson TR, Avner ED. Erratum: Functional genomics in the post-genome era (Mutation Research 400 (1998) (3-14) PII: 2002751098000232) Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998;422(2):367.
282. Wilson P, Avner E. Session VIII. Renal maldevelopment of the kidney and urinary tract Pediatric Nephrology. 1996;10(6):828-830.
283. Tapper D, Tarr P, Avner E, Brandt J, Waldhausen J. Lessons learned in the management of hemolytic uremic syndrome in children. J Pediatr Surg. 1995 Feb;30(2):158-63.
284. Holleman RC, Avner ED. Cystic disorders of the kidney in children Current Paediatrics. June 1995;5(2):80-85.
285. . From the Centers for Disease Control and Prevention. Update: multistate outbreak of Escherichia coli O157:H7 infections from hamburgers--Western United States, 1992-1993. JAMA. 1993 May 05;269(17):2194-6.
286. Kemper KJ, Avner ED. The case against screening urinalyses for asymptomatic bacteriuria in children Pediatric Nephrology. April 1993;7(2):129.
287. Sweeney WE, Avner ED. Intact organ culture of murine metanephros Journal of tissue culture methods: Tissue Culture Association manual of cell, tissue, and organ culture procedures. September 1991;13(3):163-168.
288. Zelikovic I, Avner ED. Neonatal, congenital, and hereditary disorders of the kidney and urinary tract Current Opinion in Pediatrics. 1991;3(2):250-255.
289. Tapper D, Watkins S, Burns M, Hickman RO, Avner E. Comprehensive management of renal failure in infants. Arch Surg. 1990 Oct;125(10):1276-81.
290. Osorio AM, Thun MJ, Novak RF, an Cura EJ, Avner ED. Silica and Glomerulonephritis: Case Report and Review of the Literature American Journal of Kidney Diseases. 1987;9(3):224-230.
291. Curto KA, Sweeney WE, Avner ED, Curthoys NP. Appearance of γ-glutamyltranspeptidase (γGT) during fetal development of the mouse kidney Federation Proceedings. 1985;44(5).
292. Avner ED, Ellis D, Jaffe R. Reply The Journal of Pediatrics. December 1983;103(6):1009.
293. Ingelfinger JR, Avner ED, Tolkoff-Rubin NE. Single dose amoxicillin (S) treatment of uncomplicated urinary tract infections (UTI) as effective as conventional therapy (C) Pediatric Research. 1981;15(4 II).
 
Books, Chapters, and Reviews
1. Spitzer A, Avner ED (Eds), Inheritance of Kidney and Urinary Tract Disease, Academic Publishers, The Netherlands, 1990.
2. Holliday M, Barratt M, Avner ED (eds): Pediatric Nephrology, 3rd Edition, Williams and Wilkins, 1994.
3. Barratt TM, Avner ED, Harmon W (eds): Pediatric Nephrology, 4th Edition. Lippincott, Williams and Wilkins, 1999.
4. Avner ED, Harmon W, Niaudet P (eds): Pediatric Nephrology, 5th Edition. Lippincott, Williams and Wilkins, 2004.
5. Avner ED, Kliegman RM (eds): Pediatric Clinics of North America, Volume 54 (4), Scientific Foundations of Clinical Practice, Part I. August 2006.
6. Avner ED, Kliegman RM (eds): Pediatric Clinics of North America, Volume 54 (5), Scientific Foundations of Clinical Practice, Part II. October 2006.
7. Avner ED, Harmon W, Niaudet P, Yoshikawa N (eds): Pediatric Nephrology, 6th Edition. Springer-Verlag, 2009.
8. Avner ED, Ingelfinger JR. Renal disorders: Hematuria. In: Graef J and Cone T (Eds), Manual of Pediatric Therapeutics, 2nd edition, Little, Brown and Co., 1980, pp 205-228.
9. Avner ED, Harmon WE, Ingelfinger JR, Levey RH, Grupe WE. Mortality of chronic hemodialysis comparable to that of renal transplantation in pediatric end-stage renal disease. Proc Clin Dial Transplant Forum 9:1-4, 1980.
10. Avner ED, Ingelfinger JR. Special considerations in the pediatric patient. In: Rieselbach RE and Garnick ME (Eds). Cancer and the Kidney, Lea and Feibiger, 1982, pp 275-306.
11. Avner ED, Sweeney WE, Ellis D. Serum-free organ culture of embryonic mouse metanephros. In: Sato G, Sirbasku D, and Barnes D (Eds). Cell Culture Methods for Molecular and Cell Biology, Vol. 3: Methods for Serum-Free Culture of Epithelial and Fibroblastic Cells. A.R. Liss, 1984, pp 33-43.
12. Avner ED, Ellis D. Diuretic therapy in pediatric patients. In: Puschett JB, Greenberg A (Eds). The Diuretic Manual, Elsevier Scientific Publishing Co., 1985, pp 115-126.
13. Ellis D, Avner ED. Fluid and electrolyte disorders in pediatric patients. In: Puschett JB (Ed), Disorders of Fluid and Electrolyte Balance: Diagnosis and Management, Churchill Livingstone, 1985, pp 217-230.
14. Ellis D, Avner ED. Acute and chronic renal failure. In: Schwartz GR, Safar P, Stone J, Storey P, and Wagner D (Eds). Principles and Practice of Emergency Medicine, 2nd edition, W.B. Saunders, 1986, pp 129-154.
15. Ellis D, Avner ED. Renal and genitourinary disorders in Davis H and Zitelli B (Eds). Gower Atlas of Pediatric Physical Diagnosis, Medical Publishing Ltd, 1987, pp 13.1-13.15.
16. Avner ED. Experimental aspects of renal cystic disease. In: Murakami K, Kitagawa T, Yabuta K, Sakai T (Eds). Recent Advances in Pediatric Nephrology, Elsevier, 1987, pp 389-393.
17. Avner ED. Growth factor requirements of nephrogenesis following natural embryonic induction. In: Murakami K, Kitagawa T, Yabuta K, Sakai T (Eds). Recent Advances in Pediatric Nephrology, Elsevier, 1987, pp 417-421.
18. Avner ED. Polycystic kidney disease in renal explants. In: Carone F, Dobbie JW (Eds), Advances in the Pathogenesis of Polycystic Kidney Disease, pp 137-141, Baxter, 1990.
19. Avner ED. Metanephric development in serum-free organ culture. In: Bellinger M (Ed), Dialogues in Pediatric Urology: Animal Models for the Study of Congenital Urological Disorders, 8:2-5, W. J. Miller, 1990.
20. Avner ED, Ellis D, Ichikawa I, Yared A. Normal neonates and the maturational development of homeostatic mechanisms. In: Ichikawa I (Ed), Pediatric Textbook of Fluids and Electrolytes, Williams and Wilkins, 1990, pp 107-118.
21. Avner ED, Hazinski TA, Dabbagh S, Ellis D. Fluid and electrolyte abnormalities in the stressed neonate. In: Ichikawa I (Ed), Pediatric Textbook of Fluids and Electrolytes, Williams and Wilkins, 1990, pp 402-414.
22. Avner ED, McAteer JA, Evan AP. Experimental models of cysts and cystic kidneys. In: Gardner KD, Bernstein J (eds), The Cystic Kidney, Kluwer Academic Publishers, 1990, pp 55-98.
23. Zelikovic I, Avner ED. Neonatal, congenital, and hereditary disorders of the kidneys and urinary tract. Curr Opin Pediatr 3: 250-255, 1991 Current Sciences.
24. Avner ED. Embryogenesis and anatomical development of the kidney. In: Polin RA, Fox WW (Eds), Fetal and Neonatal Physiology, W.B. Saunders, 1991, pp 1181-1187.
25. Ellis D, Avner ED. Acute and chronic renal failure. In: Schwartz GR, Cayten CG, Mangelsen MA, Mayer TA (eds), Principles and Practice of Emergency Medicine, 3rd edition, Lea and Ferbiger, 1992, pp 1592-1616.
26. Avner ED. Renal hypoplasia and dysplasia. In: Burg F, Ingelfinger J, Wald E (eds), Gellis and Kagan's Current Pediatric Therapy, 14th Edition, W.B. Saunders, 1993, pp 346-347.
27. Watkins SL, Avner ED. Renal dysplasia and renal cystic disease. In: Holliday M, Barratt M, Avner ED (eds), Pediatric Nephrology, 3rd edition, Williams and Wilkins, 1994, pp 467-490.
28. Wilson PD, Avner ED. Cell biology of polycystic kidney disease. In: Gabow PA, Grantham JJ (eds), Proceedings of the Fifth International Workshop on Polycystic Kidney Disease, PKR Foundation, 1993, pp 99-102.
29. Avner ED. Abnormal growth factor responses in PKD. In: Gabow PA, Grantham JJ (eds), Proceedings of the Fifth International Workshop on Polycystic Kidney Diseases, PKR Foundation, 1993, pp 106-108.
30. Avner ED. Medullary cystic disease and medullary sponge kidney. In: Greenberg A (ed), NKF Nephrology Primer, W.B. Saunders, 1994, pp 178-181.
31. Avner ED. Polycystic kidney disease. In: Drukker A, Grushkin A (eds), Pediatric and Adolescent Medicine: Pediatric Nephrology, Karger AG, 1994, pp 63-78.
32. Sliman G, Avner ED. OKT3 in pediatric transplant recipients. In: Tejani A, Fine R (eds), Pediatric Renal Transplantation, Wiley, 1994, pp 291-306.
33. Watkins SL, Avner ED. Henoch-Schonlein purpura. In: Jacobson H, Striker G, Klahr S (eds), Principles and Practice of Nephrology, 2nd edition, Mosby, 1995, pp 168-172.
34. McDonald R, Avner ED. Murine models of polycystic kidney disease. In: Watson M, Torres VE (eds), Polycystic Kidney Disease, Oxford University Press, 1995, pp 63-87.
35. Avner ED. The history of renal transplantation. Transpl Chron 2: 8-10, 1995.
36. Avner ED, Sweeney WE, Orellana S. Role of growth factors in cell proliferation. In: Grantham JJ, Davidow C,Foo I, Dirks JH (eds), Forefronts in nephrology: The molecular basis of renal cystic disease. Kidney Int 47: 715-732, 1995.
37. Avner ED. Academic pediatrics in the 21st century. Newsletter of the Northern Ohio Pediatric Society, July, 1996.
38. Davis ID, Vogt BA, Avner ED. Renal transplantation in infants and young children. Transplant Chronicles 4: 16-18, 1996.
39. Avner ED. Renal hypoplasia and dysplasia. In: Burg F, Ingelfinger J, Polin R, Wald E (eds), Current Pediatric Therapy 16th Edition. W.B. Saunders, 1998, pp 832-833.
40. Avner ED. Medullary cystic disease. In: Greenberg A, Cheung AK, Coffman TM, Falk RJ, Jennette JC (eds), NKF Primer on Kidney Diseases 2nd Edition. Academic Press, 1998, pp 323-328.
41. Avner ED. Medullary sponge kidney. In: Greenberg A, Cheung AK, Coffman TM, Falk RJ, Jennette JC (eds), NKF Primer on Kidney Diseases 2nd Edition. Academic Press, 1998, pp 343-344.
42. Avner ED. Progressive nephropathies: Pathophysiology and potential therapies. In: Strauss J (ed), Pediatric Nephrology: Anniversary Issues - Current Concepts in Diagnosis and Management, University of Miami Press, 2000, pp 91-101.
43. Holleman R, Avner ED. Polycystic kidney disease in children. In: Strauss J (ed), Pediatric Nephrology: Continuing Challenges, University of Miami Press, 1997, pp 3-25.
44. Brandt J, Avner ED, Hemolytic uremic syndrome. In: Neilson E, Couser WE (eds), Immunologic Renal Diseases, Raven Press, 1997, pp 1161-1179.
45. Avner ED. Embryogenesis and anatomic development of the kidney. In: Polin R, Fox WW (eds), Fetal and Neonatal Physiology, 2nd edition, W.B. Saunders, 1997, pp 1554-1559.
46. Avner ED, Of mice and men: The value of mice in the study of autosomal recessive polycystic kidney disease (ARPKD). Polycystic Kidney Foundation Newsletter, 12:4-5, 1997.
47. Avner ED. Commentary for renal transplantation, chronic dialysis, and chronic renal insufficiency in children and adolescents. The 1995 Annual Report of the North American Pediatric Renal Transplant Cooperative Study. In: Stockman JA (ed), 1998 Year Book of Pediatrics, Mosby, 1998, pp 323-324.
48. McDonald RA, Watkins SL, Avner ED. Polycystic kidney disease. In: Barratt TM, Avner ED, Harmon W (eds), Pediatric Nephrology, 4th Edition. Lippincott, Williams and Wilkins, 1999, pp 459-474.
49. Watkins SL, McDonald RA, Avner ED. Renal dysplasia, hypoplasia, and miscellaneous cystic disorders. In: Barratt TM, Avner ED, Harmon W (eds), Pediatric Nephrology 4th Edition. Lippincott Williams and Wilkins, 1999, pp 415-425.
50. Vogt BA, Davis ID, Avner ED. The Kidney. In: Klaus ME, Fanaroff AF (eds), Care of the High Risk Neonate. W.B. Saunders, 2001, pp 425-446.
51. Ellis D, Avner ED, Maino JC, Schwartz GR. Renal Failure. In: Schwartz GR, Hanke BK, Mayer TA, Cohen JS, Dunn JD, Howton JC, Isaacman DJ, Roth P, Rothrock SG, Ungar JR (eds), Principles and Practice of Emergency Medicine, 4th Edition. Williams & Wilkins, 1998, pp 33-747.
52. Avner ED. 1998 research update in polycystic kidney disease. 9th Annual Conference on Polycystic Kidney Disease (June 1998). www.pkdcure.org.
53. Avner ED (ed). Genetic diseases of the kidney. Sem Nephrol 19: (4), 1999.
54. Avner ED. Introduction: Genetic diseases of the kidney. Sem Nephrol 19: (4) 311-313, 1999.
55. Davis ID, Avner ED. Fluid and electrolyte management. In: Fanaroff AA, Martin RJ (eds), Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. Harcourt Health Sciences, 2001, pp 619-627.
56. Davis ID, Stork JE, Avner ED. Acid-base physiology and disorders in the neonate. In: Fanaroff AA, Martin RJ (eds), Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. Harcourt Health Sciences, 2001, pp 627-634.
57. Vogt BA, Avner ED. The kidney and the urinary tract. In: Fanaroff AA, Martin RJ (eds), Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. Harcourt Sciences, 2001, pp. 1517-1536.
58. Avner ED. Polycystic kidney disease. In: Burg FD, Ingelfinger JR, Polin RA, Gershon A (eds), Gellis and Kagan's Current Pediatric Therapy 17. W.B. Saunders, 2002, pp 828-831.
59. Nakanishi K, Sweeney WE, Avner ED. PKD in Childhood. In: Ito K, Asano Y, Endo H, Miterai T, Higashihara E (eds), Annual Review Kidney 2001. Chugai Igaku Co., 2001, pp 189-195.
60. Dell KM, Avner ED. Clinical presentation and evaluation of cystic disease. In: Postlethwaite RJ, Webb NJA (eds), Clinical Paediatric Nephrology, 3rd edition, Oxford University Press, 2003, pp 329-340.
61. Dell KM, Avner ED. Autosomal Recessive Polycystic Kidney Disease (July 2001). In: GeneClinics: Clinical Genetic Information Resource [database online]. Copyright, University of Washington, Seattle. Available at http://www.geneclinics.org. 2001.
62. Sweeney WE, Dell KM, Cotton CU, Carlin C, Orellana SE, Avner ED. Therapeutic intervention in PKD: An update from the Rainbow Center for Childhood PKD. Polycystic Kidney Research Foundation Newsletter, 16:12, 2001.
63. Avner ED. Medullary cystic disease. In: Greenberg AG, Cheung AK, Coffman TM, Falk RJ, Jennette JC (eds), Primer on Kidney Diseases, Third Edition. Academic Press, 2001, pp 313-316.
64. Davis ID, Avner ED. Chapters 500-514 - Glomerular Diseases; Clinical Evaluation of the Child with Hematuria; Isolated Glomerular Diseases with Recurrent Gross Hematuria; Glomerulonephritis Associated with Infections; Membranous Glomerulopathy; Membranoproliferative (Mesangiocapillary) Glomerulonephritis; Glomerulonephritis Associated with Systemic Lupus Erythematosis; Henoch-Schonlein Purpura Nephritis; Rapidly Progressive (Crescentic) Glomerulonephritis; Goodpasture Disease; Hemolytic-Uremic Syndrome; Upper Urinary Tract Causes of Hematuria; Hematologic Diseases Causing Hematuria; Anatomic Abnormalities Associated with Hematuria; Lower Urinary Tract Causes of Hematuria. In: Behrman RE, Kliegman RM, Jensen HB (eds), Nelson Textbook of Pediatrics, 17th edition, W.B. Saunders, 2003, pp 1731-1751.
65. Dell KM, Avner ED. Chapters 520-524 - Tubular Function; Renal Tubular Acidosis; Nephrogenic Diabetes Insipidus; Bartter/Gitelman Syndromes and Other Inherited Tubular Transport Abnormalities; Tubulointerstitial Nephritis. In: Behrman RE, Kliegman RM, Jensen HB (eds), Nelson Textbook of Pediatrics, 17th edition, W.B. Saunders, 2003, pp 1758-1761.
66. Vogt BA, Avner ED. Chapters 515-519, 525-527 - Introduction to the Child with Proteinuria, Transient Proteinuria, Orthostatic (Postural) Proteinuria, Fixed Proteinuria, Nephrotic Syndrome, Toxic Nephropathy, Cortical Necrosis, Renal Failure. In: Behrman RE, Kliegman RM, Jensen HB (eds), Nelson Textbook of Pediatrics, 17th edition, W.B. Saunders, 2003, 1751-1757, pp 1766-1775.
67. Sweeney WE, Avner ED. Embryogenesis and Anatomic Development of the Kidney. In: Polin RA, Fox WW, Abman SH (eds), Fetal and Neonatal Physiology, 3rd edition, W.B. Saunders, 2004, pp 1223-1228.
68. Dell KM, McDonald R, Watkins S, Avner ED. Polycystic Kidney Disease. In: Avner ED, Harmon W, Niaudet P (eds): Pediatric Nephrology, 5th Edition. Lippincott, Williams and Wilkins, 2004, pp 675-699.
69. Avner ED, Wilson P. Renal disease genes and their developmental implications. Proceedings of the 8th International Workshop on Developmental Nephrology. Ped Nephrol, 18:193-195, 2003.
70. Davis ID, Avner ED. Chapters 509-523 - Glomerular Diseases; Clinical Evaluation of the Child with Hematuria; Isolated Glomerular Diseases with Recurrent Gross Hematuria; Glomerulonephritis Associated with Infections; Membranous Glomerulopathy; Membranoproliferative (Mesangiocapillary) Glomerulonephritis; Glomerulonephritis Associated with Systemic Lupus Erythematosis; Henoch-Schonlein Purpura Nephritis; Rapidly Progressive (Crescentic) Glomerulonephritis; Goodpasture Disease; Hemolytic-Uremic Syndrome; Upper Urinary Tract Causes of Hematuria; Hematologic Diseases Causing Hematuria; Anatomic Abnormalities Associated with Hematuria; Lower Urinary Tract Causes of Hematuria. In: Kliegman RM, Behrman RE, Jensen HB (eds), Nelson Textbook of Pediatrics, 18th edition, W.B. Saunders, 2007; pp 2163-2187.
71. Dell KM, Avner ED. Chapters 529-533 - Tubular Function; Renal Tubular Acidosis; Nephrogenic Diabetes Insipidus; Bartter/Gitelman Syndromes and Other Inherited Tubular Transport Abnormalities; Tubulointerstitial Nephritis. In: Kliegman RM, Behrman RE, Jensen HB (eds), Nelson Textbook of Pediatrics, 18th edition, W.B. Saunders, 2007; pp 2197-2205.
72. Vogt BA, Avner ED. Chapters 515-519,525-527 - Introduction to the Child with Proteinuria, Transient Proteinuria, Orthostatic (Postural) Proteinuria, Fixed Proteinuria, Nephrotic Syndrome, Toxic Nephropathy, Cortical Necrosis, Renal Failure. In: Kliegman RM, Behrman RE, Jensen HB (eds), Nelson Textbook of Pediatrics, 18th edition, W.B. Saunders, 2007; pp 2178-2184; 2189-2196.
73. Greenbaum L, Avner E: Cystic Kidney Diseases. In: Clinical Pediatric Nephrology. K.K. Kher,
74. S. P. Makker, and H. W. Schnaper, eds. London, Martin Dunitz. pp 329-340, 2007.
75. Dell KM, Avner ED. Autosomal Recessive Polycystic Kidney Disease (July 2006). In: GeneClinics: Clinical Genetic Information Resource [database online]. Copyright, University of Washington, Seattle. Available at http://www.geneclinics.org. 2006.
76. Vogt BA, Avner ED. The Kidney and the Urinary Tract. In Fanaroff AA, Martin RJ (eds) Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant, 8th Edition. Harcourt Health Sciences, 2009.
77. Sweeney WE, Avner ED. Embryogenesis and Anatomic Development of the Kidney. In: Polin RA, Fox WW, Abman SH (eds), Fetal and Neonatal Physiology, 4th Edition. W. B. Saunders, 2009 (In Press).
78. Dell KM, Avner ED. Autosomal Recessive Polycystic Kidney Disease (July 2008). In: GeneClinics: Clinical Genetic Information Resource [database online]. Copyright, University of Washington, Seattle. Available at http://www.geneclinics.org. 2008.
79. Dell KM, Sweeney WE, Avner ED. Polycystic Kidney Disease. In: Avner ED, Harmon W, Niaudet P, Yoshikawa N (eds): Pediatric Nephrology, 6th Edition. Springer-Verlag, 2009; pp 849-888.
80. Pan CG, Avner ED: Chapters 508-511;514-Introduction to Glomerular Disease; Clinical Evaluation of the Child with Hematuria: Isolated Glomerular Diseases with Recurrent Gross Hematuria; Glomerulonephritis Associated With Infections; Glomerulonephritis Associated with SLE. In: Kliegman RM, Stanton BF, St.Geme J, Schor N, Berman RE (eds), Nelson Textbook of Pediatrics, 19th edition, Elsevier, 2011 (In Press)
81. 129-134 Van Why SK, Avner ED: Chapters 512-513;515-518-Membranous Glomerulopathry; Membranoproliferative Glomerulonephritis; Henoch-Schonlein Purpura Nephritis, Rapidly Progressive Glomerulonephritis; Goodpasture Disease; Hemolytic Uremic Syndrome. In: Kliegman RM, Stanton BF, St.Geme J, Schor N,Berman RE (eds), Nelson Textbook of Pediatrics,19th edition, Elsevier, 2011 (In Press)
82. 135-141 Porter CC, Avner ED: Chapters 519-521;524,525,532,533-Transient Proteinuria; Orthostatic Proteinuria, Tubulointerstitial Nephritis; Toxic Nephropathy. In: Kliegman RM, Stanton BF, St.Geme J, Schor N, Berman RE (eds), Nelson Textbook of Pediatrics,19th edition, Elsevier, 2011 (In Press)
83. 142-144 Pais P, Avner ED: Chapters 523;526,527;534-Introduction to the Child with Proteinuria; Fixed Proteinuria; Nephrotic Syndrome; Cortical Necrosis. In: Kliegman RM, Stanton BF, St.Geme J, Schor N, Berman RE (eds), Nelson Textbook of Pediatrics, 19th edition, Elsevier, 2011 (In Press)
84. 145-149 Sreedharan R, Avner ED: Chapters 528-533;535-Tubular Function; Renal Tubular Acidosis, Nephrogenic Diabetes Insipidus; Barrter/Gitelman Syndromes and Other Inherited Tubular Transport Abnormalities; Renal Failure. In: Kliegman RM, Stanton BF, St.Geme J, Schor N, Berman RE (eds), Nelson Textbook of Pediatrics, 19th edition, Elsevier, 2011 (In Press)
 
Editorials, Letters to Editor, Other
1. Avner ED Introduction: Fluid and Electrolytes. Pediatr Ann. 1995 Jan 1;24(1):15
 
Abstracts
1. Guay-Woodford LM, Bryda EC, Lindsay JR, Avner ED, Flaherty L: The mouse bpk mutation, a model of autosomal recessive polycystic kidney disease, and jcpk, a phenotypically distinct PKD mutation are allelic. Presented at the Society for Pediatric Research Annual Meeting, May 1996. Pediatr Res 39:361A, 1996.
2. Richards WG, Yoder BK, Sweeney WE, Wilkinson JE, Avner ED, Woychik RP: A hypomorphic allele of the EGF-R (Waved-2) abrogates collecting duct cyst formation in a mouse polycystic kidney disease model. Presented at the American Society of Nephrology Annual Meeting, November 1996. J Amer Soc Nephrol 7:1604, 1996.
3. Sommardahl CS, Wilkinson JE, Sweeney WE, Avner ED, Woychik RP: The effect of taxol on cystic kidney and liver lesions in the TgN737Rpw mouse model of polycystic kidney disease. Presented at the American Society of Nephrology Annual Meeting, November 1996. J Amer Soc Nephrol 7:1605, 1996.
4. Sweeney WE, Avner ED: BPK cyst fluid contains EGF and TGF-a like peptides which are mitogenic and phosphorylate apical EGF-R. Presented at the American Society of Nephrology Annual Meeting, November 1996. J Amer Soc Nephrol 7:1606, 1996.
5. Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP: Differential genetic rescue of the phenotype in an ARPKD mouse mutant: A new model to study the liver lesion and proximal tubule defects. Presented at the American Society of Nephrology Annual Meeting, November 1996. J Amer Soc Nephrol 7:1610, 1996.
6. Cotton CU, Takacs-Jarrett M, Sweeney WE, Avner ED: Conditional immortalization of murine renal collecting tubule cells. Presented at the Society of General Physiology Meeting, 1996. J Gen Physiol 108: 22A, 1996.
7. Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU: Generation of a conditionally immortalized renal cell line. Pediatr Pulm Supplement 13: A153, 1996.
8. Avner ED, Sweeney WE, Orellana S: Abnormal epidermal growth factor receptor expression in autosomal recessive polycystic kidney disease (ARPKD). Presented at the 6th International Workshop on Developmental Nephrology, Airle, VA 1995. Pediatr Nephrol 10: C180, 1996.
9. Orellana SA, Winkler DJ, Avner ED: Prostaglandin E1 and serum modulate Madin Darby canine kidney cell responses to hepatocyte growth factor. Presented at the 6th International Congress on Cell Biology and 36th American Society for Cell Biology Annual Meeting, December 1996. Mol Biol of the Cell 7: 114a, 1996.
10. Jones B, Yoder BK, Sweeney WE, Avner ED, Wilkinson JE, Woychik RP. Pattern of expression of the TG737 gene in the postnatal developing kidney. Presented at the American Society of Nephrology Annual Meeting, November, 1997, J Amer Soc Nephrol, 8:1729, 1997.
11. Yoder BK, Wilkinson JE, Avner ED, Woychik RP. The TG737 protein interacts with polycystin (PKD1) and proteins controlling epithelial polarity, EGFR stability and cellular differentiation. Presented at the American Society of Nephrology Annual Meeting, November, 1997, J Amer Soc Nephrol 8:1783, 1997.
12. Woychik RP, Murcia N, Yoder BK, Richards WG, Wilkinson JE, Dunlap J, Sweeney WE, Avner ED. Analysis of the expression and function of the TG737 polycystic kidney gene during mammalian development. Presented at the American Society of Nephrology Annual Meeting, November, 1997, J Amer Soc Nephrol 8:1779, 1997.
13. Sweeney WE, Futey L, Cotton CC, Avner ED. Isolation and characterization of conditionally immortalized principal cells from the BPK model of ARPKD. Presented at the American Society of Nephrology Annual Meeting, November 1997, J Amer Soc Nephrol 8:1761, 1997.
14. Ward DT, Sweeney WE, Avner ED, Harris HW. Purified apical membrane endosomes from rat kidney inner medullary collecting duct contain endogenous membrane-bound tyrosine kinase (TK) and phosphatase (TP) activities. Pediatr Res 43:315A, 1998.
15. Avner ED. Cellular pathophysiology of polycystic kidney disease. Presented at the 11th Congress of the International Pediatric Nephrology Association meeting, September, 1998, Ped Nephr 12:C47, 1998.
16. Sweeney WE, Murcia N, Jones B, Woychik RP, Avner ED. Expression of TG737 gene in developing kidney. Presented at the American Society of Nephrology Annual Meeting, October, 1998, J Amer Soc Nephrol 9:1952, 1998.
17. Sweeney WE, Avner ED. Proximal tubular cysts in fetal human ARPKD. Presented at the American Society of Nephrology Annual Meeting, October, 1998, J Amer Soc Nephrol 9:1953, 1998.
18. Sweeney WE, Avner ED, Elmer HL, Cotton CU. CFTR is required for cAMP-dependent in vitro renal cyst formation. Presented at the American Society of Nephrology Annual Meeting, October, 1998, J Amer Soc Nephrol 9:1954, 1998.
19. Nakanishi K, Sweeney WE, Avner ED. Segment specific C-erb B-2 expression in human autosomal recessive polycystic kidney disease (ARPKD). Presented at the American Society of Nephrology Annual Meeting, November, 1999, J Amer Soc Nephrol 10:2127, 1999.
20. Nakanishi K, LI L, Wu G, Sweeney WE, Somlo S, Avner ED. Characterization of cyst development and growth in Pkd2WS25/- mice. Presented at the American Society of Nephrology Annual Meeting, November, 1999, J Amer Soc Nephrol 10:2125, 1999.
21. Harari A, Sweeney WE, Magnuson T, Avner ED. Renal development and function in epidermal growth factor receptor (EGFR) null mice. Presented at the American Society of Nephrology Annual Meeting, November, 1999, J Amer Soc Nephrol 10:2106, 1999.
22. Nakanishi K, Gattone II V, Sweeney WE, Avner ED. Effect of exogenous epidermal growth factor (EGF) on polycystic kidney disease (PKD) in bpk cystic mice. Presented at the American Society of Nephrology Annual Meeting, November, 1999, J Amer Soc Nephrol 10:2126, 1999.
23. Onuchik LF, Hofmann Y, Mrug M, Becker J, Dixit MP, Avner ED, Somlo S, Zerres K, Guay-Woodford LM, Germino GG - ARPKD Consortium. Genomic structure and exclusion of two candidate genes for the PKHD1 locus and three new polymorphic markers within the critical interval. Presented at the American Society of Nephrology Annual Meeting, November, 1999, J Amer Soc Nephrol 10:2133, 1999.
24. Dell KM, Sweeney WE, Frost P, Levin J, Avner ED. Treatment with a novel inhibitor of transforming growth factor-alpha (TGF-α) secretion ameliorates disease in murine autosomal recessive polycystic kidney disease. Presented at the American Society of Nephrology Annual Meeting, October 2000, J Amer Soc Nephrol 11:388, 2000.
25. Nakanishi K, Sweeney WE, Dell KM, Cotton CU, Avner ED. Cystic fibrosis transmembrane conductance regulator (CFTR) activity is not required for cyst formation in murine autosomal recessive polycystic kidney disease (ARPKD) mouse model. Presented at the American Society of Nephrology Annual Meeting, October, 2000, J Amer Soc Nephrol 11:395, 2000.
26. Corsillo L, Carlin C, Sweeney WE, Avner ED. Phenotypic Analysis of Conditionally Immortalized Principal Cells Isolated from the BPK Murine Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD). Presented at the American Society of Nephrology Annual Meeting, October, 2000, J Amer Soc Nephrol 11:388, 2000.
27. Kusner L, Carlin C, Sweeney WE, Avner ED. Phenotypic analysis of conditionally immortalized principal cells isolated from the BPK murine model of ARPKD. Presented at the Annual Meeting of the American Society for Cell Biology, December 2000, Mol Biol Cell 11:489a, 2000.
28. Hamahira K, Sweeney WE, Dell KM, Frost P, Avner ED. Treatment with a second-generation tyrosine kinase inhibitor (EKB-569) alone or in combination with an inhibitor of TGF-α secretion ameliorates cyst progression in murine ARPKD. Presented at the American Society of Nephrology Annual Meeting, October 2001. Amer Soc Nephrol 12:536A, 2001.
29. Dell KM, Nemo R, Sweeney WE, Avner ED. Expression of heparin-binding EGF and amphiregulin in murine ARPKD. Presented at the American Society of Nephrology Annual Meeting, October 2001.J Amer Soc Nephrol 12:534A, 2001.
30. Wang X, Sweeney WE, Lager DJ, Harris PC, Frost P, Avner ED, Torres VE. The intraperitoneal administration of EKI-785 has opposing effects on the development of polycystic kidney disease in Han:SPRD and PCK rats. Presented at the American Society of Nephrology Annual Meeting, October 2001. J Amer Soc Nephrol 12:547A, 2001.
31. Onuchik LF, Furu L, Nagasawa Y, Mrug M, Eggerman T, Bergmann C, Sweeney WE, Avner ED, Zerres K, Guay-Woodford LM, Somlo S, Germino GG, ARPKD Consortium. Refinement of the PKHD1 interval and analysis of candidate expressed sequences. Presented at the American Society of Nephrology Annual Meeting, October, 2001.J Amer Soc Nephrol 12:543A, 2001.
32. 9, Dell KM, Vogt BA, O'Riordan MA, Avner ED, Davis ID. Complications of peritoneal dialysis (PD) in Eagle-Barrett syndrome (EBS). Presented at the Pediatric Academic Societies Annual Meeting, 2002, Ped Research, 51:433A, 2002.
33. Dell KM, Nemo R, Sweeney WE, Avner ED. Evidence for a role of multiple epidermal growth factor receptor (EGFR) ligands in the pathogenesis of ARPKD. Presented at the Pediatric Academic Societies Annual Meeting, 2002, Ped Research, 51:421A, 2002.
34. Hamahira K, Sweeney WE, Gatrell-Garcia M, Dell KM, Frost P, Avner ED. Tyrosine kinase inhibitor (EKB) alone or in combination with an inhibitor of TGF-α secretion ameliorates cyst progression in murine ARPKD. Presented at the Pediatric Academic Societies Annual Meeting, 2002, Ped Research, 51:422A, 2002.
35. Sweeney WE, Chang S, Jelinsky S, Brown G, Slocum D, Frost P, Avner ED. Expression profiling of normal and cystic collecting tubules in the BPK murine model of ARPKD. Presented at the American Society of Nephrology Annual Meeting, October, 2002. J Amer Soc Nephrol 13:117A, 2002.
36. Hamahira K, Sweeney WE, Avner ED. Role of apoptosis and proliferation on cyst formation in the BPK model of ARPKD. Presented at the American Society of Nephrology Annual Meeting, October, 2002. Presented at the American Society of Nephrology Annual Meeting, October, 2002. J Amer Soc Nephrol 13:112A, 2002.
37. Dell KM, Nemo R, Sweeney WE, Avner ED. Abnormalities in the heparin-binding EGF/ErbB4/EGFR axis in murine ARPKD. Presented at the American Society of Nephrology Annual Meeting, October, 2002. J Amer Soc Nephrol 13:107A, 2002.
38. Grimm D, Praetorius H, Cai Y, Geng L, Zeltner R, Sweeney WE, Avner ED, Somlo S, Spring K, Caplan M. A role for polycystin-2 in the cilium mechanostimulation pathway. Presented at the American Society of Nephrology Meeting, October, 2002. J Amer Soc Nephrol 13:47A, 2002.
39. Geng L, Nishimura S, Cai Y, Velazquez H, Tian X, Wu G, Sweeney WE, Avner ED, Somlo S. Cells derived from mouse kidney retain epithelial properties despite loss or over-expression of polycystin-2. Presented at the American Society of Nephrology Annual Meeting, October, 2002. J Amer Soc Nephrol 13:115A 2002.
40. Nagasawa Y, Mathiessen S, Onuchic L, Hou X, Esquivel E, Ren Z, Zeltner R, Bregmann C, Furu L, Avner ED, Moser M, Somlo S, Guay-Woodford L, Buettner R, Zerres K, Germino G. Identification and characterization of mouse Pkhd1. Presented at the American Society of Nephrology Annual Meeting, October 2002. J Amer Soc Nephrol 13:111A, 2002.
41. von Vigier RO, Sweeney WE, Avner ED. Segment-specific markers of the developing rat nephron. Presented at the Pediatric Academic Societies Annual Meeting, 2003. Ped Research 53:520A, 2003.
42. Dell KM, Nemo R, Sweeney WE, Avner ED. Transforming growth factor-alpha is not required for cystogenesis in ARPKD. Presented at the Pediatric Academic Societies Annual Meeting, 2003. Ped Research 53:516A, 2003.
43. Sweeney WE, Chang S, Frost P, Avner ED. Identification of novel therapeutic targets through expression profiling of control and cystic principal cells in the BPK murine model of ARPKD. Presented at the Pediatric Academic Societies Annual Meeting, 2003. Ped Research 53:516A, 2003.
44. von Vigier RO, Sweeney WE, Frost P, Avner ED. Inhibition of c-Src ameliorates cyst progression in murine ARPKD. Presented at the American Society of Nephrology Annual Meeting, 2003. J Amer Soc Nephrol 14:110A, 2003.
45. von Vigier RO, Sweeney WE, Duzova A, Carlin CR, Avner ED. Characterization of PKHD1 expression in murine and human ARPKD. Presented at the American Society of Nephrology Annual Meeting, 2003. J Amer Soc Nephrol 14:362, 2003.
46. Torres VE, Sweeney WE, Wang X, Qian Q, Harris PC, Frost P, Avner ED. Inhibition of epidermal growth factor receptor tyrosine kinase activity worsens in polycystic kidney disease in PCK rats. Presented at the American Society of Nephrology Annual Meeting, 2003. J Amer Soc Nephrol 14:109A, 2003.
47. Sweeney WE, von Vigier R, Carlin CR, Punashthiti R, Ward C, Harris P, Avner ED. Characterization of PKHD1 Expression in Murine and Human ARPK. Presented at the Pediatric Academic Societies Annual Meeting 2004. Ped Research 55:574A, 2004.
48. von Vigier RO, Sweeney WE, Murcia NS, Frost P, Avner ED. Receptor Tyrosine Kinase Inhibition attenuates Hepatobiliary Abnormalities in a murine model of Autosomal Recessive Polycystic Kidney Disease. Presented at The American Society of Nephrology Annual Meeting, 2004. J Amer Soc Nephrol 15:212A, 2004.
49. Sweeney WE, Avner ED. "New Therapies for PKD: From Bench to Bedside" presented at The American Society of Nephrology Annual Meeting, 2004. J Amer Soc Nephrol 15:89A, 2004.
50. Sweeney WE, Frost P, Avner ED. Inhibition of c-Src Ameliorates Cyst Progression in the PCK Rat. Presented at The Pediatric Academic Societies Annual Meeting, 2005. Washington, D.C. Ped Research 57:1509, 2005.
51. Sweeney WE, Donohoe DL, Avner ED. Inhibition of ErbB2 Decreases c-Src Activity and Ameliorates Renal and Biliary Cystic Abnormalities in the PCK Rat. J Amer Soc Nephrol 16:225A, 2005.
52. Sweeney WE, Donohoe DL, Gibbons J, Avner ED. A dual c-Src and c-Abl inhibitor decreases hepatic and renal fibrosis in an orthologous model of autosomal recessive polycystic kidney disease (ARPKD). Presented at The Pediatric Academic Societies Meeting, 2006. San Francisco, California. Ped Research 59:149 (#4804.40), 2006.
53. Sweeney WE, Donohoe DL, Gibbons J, Avner ED. Pan-ErbB2 Receptor Inhibition Decreases Hepatic and Renal Fibrosis in an Orthologous Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD). Presented at The Pediatric Academic Societies Meeting, 2006. San Francisco, California. Ped Research 59:149 (#4804.41), 2006
54. Sweeney WE, Donohoe DL, Avner ED. Therapeutic Potential of pp60(cSrc) Inhibition in Autosomal Dominant Polycystic Kidney Disease (ADPKD). Presented at the American Society of Nephrology Annual Meeting, 2006, San Diego, California. J Amer Soc Nephrol 17:778A, 2006.
55. Sweeney WE, Park F, Donohoe DL, Avner ED. The Role of 20-HETE. An Arachidonic Acid Metabolite on Cellular Proliferation in Autosomal Recessive Polycystic Kidney Disease (ARPKD). Presented at the Annual Meeting of the Pediatric Academic Societies, Toronto, Canada, 2007. Ped Research 61:197 (#7918.9), 2007.
56. Elliott J, Israeli S, Sweeney WE, Avner ED, Wilson P. c-Src is Effective as Therapy for ADPKD. American Society of Nephrology Annual Meeting. San Francisco. November 2007. J Am Soc Nephrol 18: 364A, 2007
57. Park F, Sweeney WE, Jia G, Roman RJ, Avner ED. Contribution of cytochrome P450 metabolites to the abnormal proliferation of renal epithelial cells in a murine model of PKD. American Society of Nephrology Annual Meeting. San Francisco, California. November 2007. J Am Soc Nephrol 18: 129A, 2007
58. Park F, Sweeney WE, Avner, ED. Chronic blockade of 20-HETE production attenuates cyst formation in a rodent model of Autosomal Recessive Polycystic Kidney Disease. Presented at the Pediatric Academic Societies, Honolulu, Hawaii. May 2008
59. Moreno Quinn C, Sweeney WE, Lazar J, Jacob, H, Avner ED. Development of a Rat Model of ARPKD to Study Genetic Modifier Loci. Presented at the American Society of Nephrology Annual Meeting, Philadelphia, Pennsylvania. Poster Session (#F-PO1119), November 2008.
60. Park F, Jia G, Akbulut T, Sweeney WE, Avner ED. Chronic Inhibition of Angiotensin Converting Enzyme Improves Renal Function. Presented at the American Society of Nephrology Annual Meeting, Philadelphia, Pennsylvania. Poster Session (#SA-PO2402), November 2008.
61. Nadella R, Blumer JB, Qian F, Sweeney WE, Avner ED, Wilson PD, Lanier SM, Park F. Aberrant Expression of AGS3 in Genetic Models of Polycystic Kidney Disease. Presented at the American Society of Nephrology Annual Meeting, San Diego, California. Poster Session (#F-PO1660) October 2009.
62. Sweeney WE, Nozu K, Peters DJM, Avner ED. Characterization of a Hypomorphic Pkd1 Mouse Model of ADPKD. Abstract (3481) Presented at the Renal Week 2010 of the American Society of Nephrology, Denver, Colorado. November 2010.
63. Sweeney WE, Nozu K, Frost P, Schwasinger E, Avner ED. Multi-kinase inhibition effectively ameliorates renal cystic disease in preclinical models of PKD. Abstract - to be presented at the 2011 Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference, Saxtons River, Vermont. June 2011.
64. O'Meara C, Sweeney WE, Hoffman M, Yeo NC, Tsaih SW, Lazar J, Jacob HJ, Avner ED, Moreno C. Role of genetic modifiers in an orthologous model of ARPKD. Abstract - to be presented at the 2011 Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference, Saxtons River, Vermont. June 2011.
65. Li X, Avner ED. Abstract - to be presented at the 2011 Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference, Saxtons River, Vermont. June 2011.