CURRICULUM VITAE
Guilherme Garcia PhD
Guilherme Garcia PhD
Assistant Professor
Department of Biomedical Engineering
Department of Biomedical Engineering
OFFICE ADDRESS: |
Translational and Biomedical Research Center |
8701 Watertown Plank Rd |
Milwaukee, WI 53226 |
Phone: 414-955-4466 |
Fax: 414-955-6568 |
Email: ggarcia@mcw.edu |
EDUCATION: |
03/1996 - 07/1999 BS in Physics, Universidade Federal de Minas Gerais, Brazil |
08/1999 - 07/2001 MS in Physics, Universidade Federal de Minas Gerais, Brazil |
08/2001 - 01/2005 PhD in Physics, Universidade Federal de Minas Gerais, Brazil |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
03/2005 - 10/2008 Postdoctoral Fellow, Computational Biology Division, The Hamner Institutes for Health Sciences, Research Triangle Park, NC |
11/2008 - 01/2011 Postdoctoral Fellow, Department of Pharmacology, University of North Carolina, Chapel Hill, NC |
02/2011 - 02/2012 Postdoctoral Fellow, Universidade Federal de Minas Gerais, Brazil |
FACULTY APPOINTMENTS: |
03/2012 - 09/2012 Assistant Professor, Universidade Federal de São João Del Rei, Ouro Branco, MG, Brazil |
10/2012 - Present Assistant Professor, Department of Otolaryngology and Communication Sciences, Division of Research, Medical College of Wisconsin, Milwaukee, WI |
08/2016 - Present Assistant Professor, Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI |
ADMINISTRATIVE APPOINTMENTS: |
01/2011 - 12/2011 Organizer, Biophysics Seminar Series, Department of Physics, Universidade Federal de Minas Gerais |
03/2014 - 12/2014 Organizer, Biomedical Engineering Seminar Series (8 seminars during 2014), Biotechnology & Bioengineering Center, Medical College of Wisconsin |
AWARDS AND HONORS: |
10/2012 Best Poster Award, received by my M.S. student Tauanne Amarante, X-meeting 2012, Signaling and Metabolic Networking, Ontologies, Systems Biology |
05/09/2014 Medical College of Wisconsin Affiliated Hospital (MCWAH) Research Award, received by my student Corbin Sullivan M.D. for the research conducted during his resident research rotation, Medical College of Wisconsin |
10/13/2014 Best Poster Award in the 2014 Medical Student Research Day Poster Session, received by my student Gabriel Oland (3rd highest score among 115 posters), Medical College of Wisconsin |
10/19/2014 Best Resident Basic Science Research Award, received by my student Ruchin Patel M.D. for the research conducted during his resident research rotation, Wisconsin Society of Otolaryngology meeting |
04/14/2015 2015 AOA Carolyn L. Kuckein Student Research Fellowship award, received by my student Courtney Gaberino to conduct summer research in my lab, Alpha Omega Alpha Honor Medical Society |
10/15/2015 Best Poster Award in the 2015 Medical Student Research Day Poster Session, received by my student Courtney Gaberino (7th highest score among 106 posters), Medical College of Wisconsin |
05/19/2016 Best Poster Award, received by my student Courtney Gaberino (2nd place among 95 posters), American Rhinologic Society (ARS) meeting at the Combined Otolaryngology Spring Meetings (COSM) 2016 |
12/2018 Outstanding Graduate School Educator, Academic Year 2017-2018, Medical College of Wisconsin |
09/2019 Community of Innovators Award, Medical College of Wisconsin |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
2001 - Present Brazilian Physics Society |
2012 - Present Biophysical Society |
2014 - Present American Physics Society |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
08/2013 - Present Member, Resident Research Committee (reviews 3 resident research projects per year), Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
International |
Guilherme Garcia, Improving nasal surgery through bioengineering, IV Rhinology 2008, Sao Paulo, Brazil, 05/22/2008 - 05/24/2008 |
Regional |
Guilherme Garcia, Applying CFD to understand nasal physiology: atrophic rhinitis, a seminal study, 2007 ANSYS U.S. Regional Conference Series: California, San Diego, CA, 04/03/2007 - 04/05/2007 |
Guilherme Garcia, Fluid homeostasis and its influence on cilia motility, Mathematical and Computational Challenges in Cilia- and Flagella-Induced Fluid Dynamics, Ohio State University, 10/16/2012 |
Guilherme Garcia, Experimental validation of nasal airflow computer simulations using patient-specific models, IEEE USA Annual Meeting 2015 & 36th Great Lakes Biomedical Conference, Milwaukee, WI, 05/15/2015 |
Local |
Guilherme Garcia, Atrophic rhinitis: is there a relation between airflow and pathophysiology?, Department of Otolaryngology/Head and Neck Surgery, University of North Carolina at Chapel Hill, 09/07/2006 |
Guilherme Garcia, Computational model of extracellular nucleotide regulation in airway epithelia, Cystic Fibrosis Focus Group, University of Illinois at Urbana-Champaign, 06/18/2009 |
Guilherme Garcia, Electrophysiology of the respiratory epithelium: regulation of mucus hydration in cystic fibrosis patients, Department of Physiology and Biophysics, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil, 06/18/2010 |
Guilherme Garcia, Computational Fluid Dynamics applied to nasal physiology, Ear-nose-throat surgeons weekly meeting, Santa Casa Hospital, Belo Horizonte, Brazil, 06/13/2012 |
Guilherme Garcia, Can computer modeling become a diagnostic and surgical-planning tool in Rhinology?, MCW Summer Program for Undergraduate Research, Medical College of Wisconsin, 06/27/2013 |
Guilherme Garcia, Finite element analysis: a tool in computational biology, BBC Teachers Workshop, Medical College of Wisconsin, 07/11/2013 |
Guilherme Garcia, Towards virtual surgery of the nasal cavity using computational fluid dynamics, Marquette University, 03/28/2014 |
Guilherme Garcia, A career in Physics and Medicine, MCW Summer Program for Undergraduate Research, Medical College of Wisconsin, 07/18/2014 |
Guilherme Garcia, Towards virtual surgery of the nasal cavity using computational fluid dynamics, Class for grad students in Mechanical Engineering Department, UWM, 11/19/2015 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
International |
Garcia G.J.M., Dickman R., On the thresholds, probabilitiy densities and critical exponents of Bak-Sneppen-like models, LAWNP03 (VIII Latin American Workshop on Non-linear Physics), Salvador, BA, Brazil, 09/28/2003 - 10/03/2003 |
Garcia G.J.M., Martins D.A., Bailie N., Kimbell J.S., Investigation of atrophic rhinitis in humans using computational fluid dynamics models of the nasal passages, American Thoracic Society 2006 International Conference, San Diego, CA, USA, 05/19/2006 - 05/24/2006 |
Kimbell J.S., Kalisak D.L., Garcia G.J.M., Use of stereolithography to confirm computational fluid dynamics studies of nasal airflow patterns in atrophic rhinitis patient, American Thoracic Society 2006 International Conference, San Diego, CA, USA, 05/19/2006 - 05/24/2006 |
Garcia G.J.M., Carey S.A., Taylor A.B., Borhan A., Ultman J.S., Harkema J.R., Kimbell J.S., Ozone Uptake in the Nasal Passages of the Infant Rhesus Monkey: Predicting Lesion Location with Computational Fluid Dynamics, International Science Forum on Computational Toxicology, Research Triangle Park, NC, USA, 05/21/2007 - 05/23/2007 |
Kimbell J.S., Garcia G.J.M., Stanek J.J., Foureman G.L., Nasal Dosimetry in Childhood: Construction of Anatomically-Accurate Models, International Science Forum on Computational Toxicology, Research Triangle Park, NC, 05/21/2007 - 05/23/2007 |
Garcia G.J.M., Hariri B.M., Patel R.G., Rhee J.S., The relationship between nasal resistance to airflow and the airspace minimal cross-sectional area, 26th Congress of the European Rhinologic Society, Stockholm, Sweden, 07/03/2016 - 07/07/2016 |
National |
Garcia G.J.M., Dickman R., Critical exponents for anisotropic Bak-Sneppen models, XXVI National Meeting of Condensed Matter Physics (In Portuguese), Caxambu, MG, Brazil, 05/06/2003 - 05/10/2003 |
Garcia G.J.M., da Silva J.K.L., A model for the scaling of mammalian long bones, XXVI National Meeting of Condensed Matter Physics (In Portuguese), Caxambu, MG, Brazil, 05/06/2003 - 05/10/2003 |
Garcia G.J.M., Dickman R., Functional equations in modified Bak-Sneppen models, XXVI National Meeting of Condensed Matter Physics (In Portuguese), Caxambu, MG, Brazil, 05/06/2003 - 05/10/2003 |
Garcia G.J.M., da Silva J.K.L, A model for the scaling of mammalian long bones, X Brazilian Biomechanics Conference (In Portuguese), Ouro Preto, MG, Brazil, 06/03/2003 - 06/06/2003 |
Garcia G.J.M., Dickman R., The Bak-Sneppen model with absorbing states, XXVII National Meeting of Condensed Matter Physics (In Portuguese), Poços de Caldas, MG, Brazil, 05/04/2004 - 05/08/2004 |
Garcia G.J.M., Dickman R., Vieira M.N., Martins D.A., Airflow in the human nose: What is known and future perspectives, 37th Brazilian Otolaryngology Conference (In Portuguese), Fortaleza, CE, Brazil, 11/16/2004 - 11/20/2004 |
Garcia G.J.M., Bailie N., Martins D.A., Kimbell J.S., Atrophic rhinitis: A computational study of air conditioning in the nasal cavity, 38th Brazilian Otolaryngology Conference (In Portuguese), Salvador, BA, Brazil, 11/27/2006 - 12/01/2006 |
Garcia G.J.M., Tewksbury E.W., Wong B.A., Kimbell J.S., How efficiently does an atrophic nose filter the air?, 38th Brazilian Otolaryngology Conference (In Portuguese), Salvador, BA, Brazil, 11/27/2006 - 12/01/2006 |
Wong B.A., Tewksbury E.W., Garcia G.J.M., Kimbell J.S., Deposition efficiency of inhaled particles from 30 nm to 10 µm in different individual human nasal replicas, Society of Toxicology (SOT) 46th Annual Meeting, Charlotte, NC, USA, 03/25/2007 - 03/29/2007 |
Garcia G.J.M., Mitchell G., Martins D.A., Bailie N., Bernard E., Watterson J., Kimbell J.S., Can nasal symptoms be explained by abnormal airflow patterns in atrophic rhinitis?, 53rd Annual Meeting of the American Rhinologic Society, Washington, DC, USA, 09/15/2007 |
Garcia G.J.M., Nazridoust K., Kimbell J.S, Nanoparticle deposition in the rat nasal cavity: prediction of dose to the olfactory epithelium, Society of Toxicology (SOT) 47th Annual Meeting, Seattle, WA, USA, 03/16/2008 - 03/20/2008 |
Tewksbury E.W., Garcia G.J.M., Kimbell J.S., Wong B.A., Inter-human variability in nasal filtration of inhaled particles among nasal replicas of four healthy individuals, Respiratory Drug Delivery 2008, Scottsdale, AZ, USA, 05/11/2008 - 05/15/2008 |
Garcia G.J.M., Boucher R.C., Elston T.C, A model of water and ion transport in airway epithelia: CF vs. Normal cells, 24th Annual North American Cystic Fibrosis Conference, Baltimore, MA, USA, 10/21/2010 - 10/23/2010 |
Garcia G.J.M., Rhee J.S., Senior B.A., Kimbell J.S., Septal deviation and nasal resistance: An investigation using virtual surgery and computational fluid dynamics, Brazilian Physics Meeting 2011 (In Portuguese), Foz do Iguaçu, PR, Brazil, 06/05/2011 - 06/10/2011 |
Amarante T.D., Garcia G.J.M., da Silva J.K.L., Computational model for the regulation of extracellular nucleotides in the airway surface liquid lining the human respiratory tract, 1st Brazilian Workshop on Cellular Electrophysiology (In Portuguese), Belo Horizonte, MG, Brazil, 04/26/2012 - 04/28/2012 |
Garcia G.J.M., da Silva J.K.L., Scaling in biology - Bone allometry, XXV National Meeting of Condensed Matter Physics (In Portuguese), Caxambu, MG, Brazil, 05/07/2012 - 05/11/2012 |
Garcia G.J.M., Schroeter J.D., Kimbell J.S., Filtration of inhaled particles and toxic gases in the human nasal cavity, XXXV National Meeting of Condensed Matter Physics (In Portuguese), Águas de Lindóia, SP, Brazil, 05/14/2012 - 05/18/2012 |
Sullivan C.D., Garcia G.J.M., Frank D.O., Kimbell J.S., Rhee J.S., Perception of nasal patency correlates with changes in mucosal cooling after surgery for nasal obstruction, American Academy of Otolaryngology Annual Meeting 2013, Vancouver, Canada, 09/29/2013 - 10/02/2013 |
Garcia G.J.M., Amarante T.D , da Silva J.K.L, Effects of liquid height on the kinetics of extracellular nucleotides in airway epithelia, 27th Annual North American Cystic Fibrosis Conference, Salt Lake City, UT, USA, 10/17/2013 - 10/19/2013 |
Garcia G.J.M., Patel R., Frank-Ito D.O., Kimbell J.S., Rhee J.S., Computational streamline rhinometry: A novel method to evaluate nasal anatomy, Combined Otolaryngology Spring Meetings 2014 / American Rhinologic Society Spring Meeting 2014, Las Vegas, NV, USA, 05/14/2014 - 05/18/2014 |
Patel R., Garcia G.J.M., Frank-Ito D.O., Kimbell J.S., Rhee J.S., A method to quantify the confounding effect of the nasal cycle on nasal airway obstruction, American Academy of Otolaryngology Annual Meeting 2014, Orlando, FL, USA, 09/21/2014 - 09/24/2014 |
Straza M., Garcia G.J.M., Hariri B., Patel R., Albano K., Schultz C., Friedland D., Bovi J., Gamma Knife Radiosurgery for Acoustic Neuroma: Assessment of Quality and Outcomes, 2014 Meeting of the Society for Neuro Oncology, Miami, FL, USA, 11/13/2014 - 11/16/2014 |
Garcia G.J.M., Sullivan C.D., Frank-Ito D.O., Kimbell J.S., Rhee J.S., Perception of Better Nasal Patency Correlates with Increased Mucosal Cooling after Surgery for Nasal Obstruction, 67th Annual Meeting Division of Fluid Dynamics, American Physical Society, San Francisco, CA, USA, 11/23/2014 - 11/25/2014 |
Leschke T.M., Garcia G.J.M., Bock J.M., Computational fluid dynamic analysis of laryngeal particle deposition from inhaled corticosteroids, 2015 Annual Meeting of the American Laryngological Association at Combined Otolaryngological Spring Meetings (COSM), Boston, MA, USA, 04/22/2015 - 04/23/2015 |
Kimbell J.S., Garcia G.J.M., Frank-Ito D.O., Lazarow F.B., Protsenko D.E., Chen Z., Wong B.J., Upper airway reconstruction using anatomic optical coherence tomography: Effects of airway bend on airflow resistance, 2015 American Society of Pediatric Otolaryngology (ASPO) Spring Meeting at the Combined Otolaryngology Spring Meetings (COSM), Boston, MA, USA, 04/24/2015 - 04/26/2015 |
Dayal A., Rhee J.S., Garcia G.J.M., Impact of Middle vs. Inferior Turbinectomy on Nasal Aerodynamics, 2015 American Academy of Otolaryngology Head and Neck Surgery Annual Meeting, Dallas, TX, USA, 09/27/2015 - 09/30/2015 |
Gaberino C., Rhee J.S., Garcia G.J.M., Estimates of nasal airflow at the nasal cycle mid-point improve the correlation between objective and subjective measures of nasal patency, 2016 American Rhinologic Society (ARS) meeting at the Combined Otolaryngology Spring Meetings (COSM), Chicago, IL, USA, 05/19/2016 - 05/20/2016 |
Bailey R.S., Casey K., Pawar S.S., Garcia G.J.M., Nasal mucosa temperature in healthy individuals and its correlation to subjective nasal patency, 2016 American Rhinologic Society (ARS) meeting at the Combined Otolaryngology Spring Meetings (COSM), Chicago, IL, USA, 05/19/2016 - 05/20/2016 |
Borojeni A.A.T., Frank-Ito D.O., Kimbell J.S., Koenig L.J., Garcia G.J.M., Rhee J.S., Comparison of nasal airflow simulations in healthy nasal cavity models built from cone beam vs. conventional computed tomography, 2016 American Rhinologic Society (ARS) meeting at the Combined Otolaryngology Spring Meetings (COSM), Chicago, IL, USA, 05/19/2016 - 05/20/2016 |
Chivukula V.K., McGah P., Prisco A.R., Beckman J.A., Garcia G.J.M., Mahr C., Aliseda A., Apical inflow angulation and left ventricle size may impact LVAD thrombosis risk, Summer Biomechanics, Bioengineering, and Biotransport Conference, National Harbor, MD, USA, 06/29/2016 - 07/02/2016 |
Garcia G.J.M., Leschke T.M., Blumin J.H., Bock J.M., Computational Fluid Dynamics Analysis of Laryngeal Particle Deposition from Inhaled Corticosteroids, Modeling Laryngeal Biology, Madison, WI, USA, 07/07/2016 |
Perkins E., Kimbell J.S., Garcia G.J.M., Buckmire R., Shah R., Use of computational fluid dynamics to predict glottic deposition of inhaled corticosteroids in the setting of vocal fold granulomas, The 2016 Fall Voice Conference, Scottsdale, AZ, USA, 10/13/2016 - 10/15/2016 |
Garcia G.J.M., Cherobin G., Casey K.P., Borojeni A.A.T., Koenig L.J., Voegels R., Rhee J.S., Effects of mucosal decongestion on nasal aerodynamics, 2016 American Academy of Otolaryngology Head and Neck Surgery Annual Meeting, San Diego, CA, USA, 10/18/2016 - 10/21/2016 |
Casey K.P., Garcia G.J.M., Borojeni A.A.T., Koenig L.J., Rhee J.S, Intranasal airflow distribution and perception of nasal patency, 2016 American Academy of Otolaryngology Head and Neck Surgery Annual Meeting, San Diego, CA, USA, 10/18/2016 - 10/21/2016 |
Garman K., Woodson B.T., Garcia G.J.M, Collapsible silicone tubes: an in vitro model for tracheal traction, 2016 American Academy of Otolaryngology Head and Neck Surgery Annual Meeting, San Diego, CA, USA, 10/18/2016 - 10/21/2016 |
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: |
High School Students |
07/01/2014 - 07/31/2014 Sean Flannery, Volunteer; During his research experience at MCW, Sean developed 3-dimensional models of the nasal anatomy, Medical College of Wisconsin |
Undergraduate Students |
05/30/2013 - 08/02/2013 Andrew Summers, Summer Research Program in Biomedical Engineering, Medical College of Wisconsin |
02/03/2014 - 06/02/2014 Benjamin Hariri, Volunteer (future medical student); During his research experience at MCW, Benjamin was involved in several research projects that resulted in 1 manuscript and 1 conference abstract., Medical College of Wisconsin |
05/27/2014 - 08/08/2014 Andrew Summers, Summer Research Program in Biomedical Engineering, Medical College of Wisconsin |
Medical Students |
08/01/2013 - 06/30/2015 Thomas Leschke, Research project during M2, M3, and M4 years supervised by myself and Dr. Jonathan Bock, which resulted in an oral presentation at COSM 2015, Medical College of Wisconsin |
11/01/2013 - 06/30/2016 Anupriya Dayal, Pathways (M1, M2, and M3 years), Medical College of Wisconsin |
11/01/2013 - 06/30/2015 Gabriel Oland, Pathways (M1 and M2 years), Medical College of Wisconsin |
11/01/2013 - 06/30/2016 Ryan Bailey, Pathways (M1, M2, and M3 years), Medical College of Wisconsin |
03/01/2014 - 06/30/2014 Shuyan Wei, Literature review on the effects of air temperature and humidity on mucociliary clearance, Medical College of Wisconsin |
05/01/2014 - 06/30/2016 Anthony Prisco, Dr. Prisco is an MD/PhD student who recently finished his PhD and is currently in his M3 year. Our research project aims to model the fluid mechanics of blood flow in patients with ventricular assistance devices, Medical College of Wisconsin |
05/28/2014 - 08/08/2014 Ryan Bailey, Medical Student Summer Research Program, Medical College of Wisconsin |
05/28/2014 - 07/25/2014 Gabriel Oland, Medical Student Summer Research Program, Medical College of Wisconsin |
11/01/2014 - 06/30/2016 Courtney Gaberino, Pathways (M1 and M2 years), Medical College of Wisconsin |
06/01/2015 - 08/11/2015 Courtney Gaberino, Medical Student Summer Research Program, Medical College of Wisconsin |
09/17/2015 - 06/30/2017 Jaroslaw Janczy, Pathways (M1 and M2 years), Medical College of Wisconsin |
11/01/2015 - 06/30/2017 Emily Lin, Pathways (M1 and M2 years), Medical College of Wisconsin |
11/01/2015 - 01/19/2018 Courtney Gaberino, Honors in Research Thesis, Medical College of Wisconsin |
Residents |
10/01/2012 - 03/31/2013 Corbin Sullivan, 3rd year resident in otolaryngology, Research rotation resulted in 2 publications in peer-reviewed journals, Medical College of Wisconsin |
11/01/2013 - 03/31/2014 Ruchin Patel, 3rd year resident in otolaryngology, Research rotation resulted in 2 publications in peer-reviewed journals, Medical College of Wisconsin |
11/01/2015 - 03/31/2016 Kevin Casey, 3rd year resident in otolaryngology, Research rotation resulted in 2 publications in peer-reviewed journals, Medical College of Wisconsin |
07/01/2016 - 11/30/2016 Derek Vanhille, 3rd year resident in otolaryngology, Research rotation resulted in 1 publication in a peer-reviewed journal, Medical College of Wisconsin |
EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Graduate Students |
MS Students Advised |
02/2011 - 01/2012 Tauanne Dias Amarante, Computational model for the regulation of extracellular nucleotides in the airway surface liquid lining the human respiratory tract., Universidade Federal de Minas Gerais |
09/01/2015 - Present Kevin Garman, Experimental studies of fluid-structure interactions in collapsible tubes, Marquette University |
PhD Students Advised |
08/01/2011 - 06/30/2016 Giancarlo Cherobin, M.D., Rhinomanometry performed via computational fluid dynamics, Universidade de Sao Paulo, Brazil |
COMMUNITY SERVICE ACTIVITIES: |
09/23/2013 Reviewer, Poster contest, Medical Student Summer Research Program 2013 |
09/29/2014 Reviewer, Poster contest, Medical Student Summer Research Program 2014 |
07/30/2015 Judge, Oral presentations, Undergraduate Summer Program 2015 |
10/01/2015 Reviewer, Poster contest, Medical Student Summer Research Program 2015 |
12/02/2015 - 12/07/2015 Honors in Research award (2 theses reviewed) |
10/13/2016 Reviewer, Poster contest, Medical Student Summer Research Program 2016 |
10/05/2017 Reviewer, Poster contest, Medical Student Summer Research Program 2017 |
11/08/2018 Reviewer, Poster contest, Annual Graduate School Poster Session 2018 |
CLINICAL RESEARCH SCHOLARS PROGRAM: |
09/10/2013 - 06/23/2015 This program’s goal is to enable each Clinical Research Scholar to successfully compete for research funding. Each meeting (2 per month) starts with an hour-long seminar on topics related to clinical research (e.g., grant writing), tools available to researchers (e.g., biostatistics support, clinical databases), and career-development (e.g., time management). Each seminar is followed by an hour-long small group session, in which scholars review each other’s grants and manuscripts in a style similar to NIH study sections. |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Garcia GJM, Woodson BT. The collapsing anatomical structure is not always the primary site of flow limitation in obstructive sleep apnea. J Clin Sleep Med. 2020 Mar 15;16(3):345-346. PMCID: PMC7075099 |
2. Garcia GJM. lapdMouse: a data archive for advancing computational models of inhaled aerosol dosimetry. J Appl Physiol (1985). 2020 Feb 01;128(2):307-308. PMCID: PMC7052587 |
3. Moghaddam MG, Garcia GJM, Frank-Ito DO, Kimbell JS, Rhee JS. Virtual septoplasty: a method to predict surgical outcomes for patients with nasal airway obstruction. Int J Comput Assist Radiol Surg. 2020 Apr;15(4):725-735. PMCID: PMC7148186 |
4. Borojeni AAT, Garcia GJM, Moghaddam MG, Frank-Ito DO, Kimbell JS, Laud PW, Koenig LJ, Rhee JS. Normative ranges of nasal airflow variables in healthy adults. Int J Comput Assist Radiol Surg. 2020 Jan;15(1):87-98. PMCID: PMC6939154 |
5. Le TB, Moghaddam MG, Woodson BT, Garcia GJM. Airflow limitation in a collapsible model of the human pharynx: physical mechanisms studied with fluid-structure interaction simulations and experiments. Physiol Rep. 2019 May;7(10):e14099. PMCID: PMC6530458 |
6. Newsome H, L Lin E, Poetker DM, Garcia GJM. Clinical Importance of Nasal Air Conditioning: A Review of the Literature. Am J Rhinol Allergy. 2019 Nov;33(6):763-769. |
7. Frank-Ito DO, Kimbell JS, Borojeni AAT, Garcia GJM, Rhee JS. A hierarchical stepwise approach to evaluate nasal patency after virtual surgery for nasal airway obstruction. Clin Biomech (Bristol). 2019 Jan;61:172-180. PMCID: PMC6813815 |
8. Kimbell JS, Basu S, Garcia GJM, Frank-Ito DO, Lazarow F, Su E, Protsenko D, Chen Z, Rhee JS, Wong BJ. Upper airway reconstruction using long-range optical coherence tomography: Effects of airway curvature on airflow resistance. Lasers Surg Med. 2019 Feb;51(2):150-160. PMCID: PMC6424583 |
9. Ganjaei KG, Soler ZM, Mappus ED, Worley ML, Rowan NR, Garcia GJM, Matthews LJ, Dubno JR, Eckert MA, Schlosser RJ. Radiologic changes in the aging nasal cavity. Rhinology. 2019 Apr 01;57(2):117-124. PMCID: PMC6543530 |
10. Vanhille DL, Garcia GJM, Asan O, Borojeni AAT, Frank-Ito DO, Kimbell JS, Pawar SS, Rhee JS. Virtual Surgery for the Nasal Airway: A Preliminary Report on Decision Support and Technology Acceptance. JAMA Facial Plast Surg. 2018 Jan 01;20(1):63-69. PMCID: PMC5833667 |
11. Cherobin GB, Voegels RL, Gebrim EMMS, Garcia GJM. Sensitivity of nasal airflow variables computed via computational fluid dynamics to the computed tomography segmentation threshold. PLoS One. 2018;13(11):e0207178. PMCID: PMC6239298 |
12. Lin EL, Bock JM, Zdanski CJ, Kimbell JS, Garcia GJM. Relationship between degree of obstruction and airflow limitation in subglottic stenosis. Laryngoscope. 2018 Jul;128(7):1551-1557. PMCID: PMC5967982 |
13. Perkins EL, Basu S, Garcia GJM, Buckmire RA, Shah RN, Kimbell JS. Ideal Particle Sizes for Inhaled Steroids Targeting Vocal Granulomas: Preliminary Study Using Computational Fluid Dynamics. Otolaryngol Head Neck Surg. 2018 Mar;158(3):511-519. PMCID: PMC5832637 |
14. Ganjaei KG, Soler ZM, Mappus ED, Taylor RJ, Worley ML, Mulligan JK, Mattos JL, Rowan NR, Garcia GJM, Dubno JR, Eckert MA, Matthews LJ, Schlosser RJ. Novel Radiographic Assessment of the Cribriform Plate. Am J Rhinol Allergy. 2018 May;32(3):175-180. PMCID: PMC6346299 |
15. Casey KP, Borojeni AA, Koenig LJ, Rhee JS, Garcia GJ. Correlation between Subjective Nasal Patency and Intranasal Airflow Distribution. Otolaryngol Head Neck Surg. 2017 Apr;156(4):741-750. PMCID: PMC6062004 |
16. Gaberino C, Rhee JS, Garcia GJ. Estimates of nasal airflow at the nasal cycle mid-point improve the correlation between objective and subjective measures of nasal patency. Respir Physiol Neurobiol. 2017 Apr;238:23-32. PMCID: PMC5316304 |
17. Prisco AR, Aliseda A, Beckman JA, Mokadam NA, Mahr C, Garcia GJM. Impact of LVAD Implantation Site on Ventricular Blood Stagnation. ASAIO J. 2017;63(4):392-400. PMCID: PMC5478478 |
18. Bailey RS, Casey KP, Pawar SS, Garcia GJ. Correlation of Nasal Mucosal Temperature With Subjective Nasal Patency in Healthy Individuals. JAMA Facial Plast Surg. 2017 Jan 01;19(1):46-52. PMCID: PMC5247324 |
19. A T Borojeni A, Frank-Ito DO, Kimbell JS, Rhee JS, Garcia GJM. Creation of an idealized nasopharynx geometry for accurate computational fluid dynamics simulations of nasal airflow in patient-specific models lacking the nasopharynx anatomy. Int J Numer Method Biomed Eng. 2017 May;33(5). PMCID: PMC5311034 |
20. Pawar SS, Garcia GJ, Rhee JS. Advances in Technology for Functional Rhinoplasty: The Next Frontier. Facial Plast Surg Clin North Am. 2017 May;25(2):263-270. |
21. Aliseda A, Chivukula VK, Mcgah P, Prisco AR, Beckman JA, Garcia GJ, Mokadam NA, Mahr C. LVAD Outflow Graft Angle and Thrombosis Risk. ASAIO J. 2017;63(1):14-23. PMCID: PMC5201113 |
22. Garcia GJM, Hariri BM, Patel RG, Rhee JS. The relationship between nasal resistance to airflow and the airspace minimal cross-sectional area. J Biomech. 2016 Jun 14;49(9):1670-1678. PMCID: PMC4885785 |
23. Dayal A., Rhee J.S., Garcia G.J.M. (2016) Impact of Middle vs. Inferior Total Turbinectomy on Nasal Aerodynamics. Otolaryngology Head and Neck Surgery, in press. DOI 10.1177/0194599816644915. |
24. Garcia GJ, Schroeter JD, Kimbell JS. Olfactory deposition of inhaled nanoparticles in humans. Inhal Toxicol. 2015;27(8):394-403. PMCID: PMC4745908 |
25. Garcia GJ, Patel RG, Frank-Ito DO, Kimbell JS, Rhee JS. Response to Dr Chung's Question on Simulating the Nasal Cycle with Computational Fluid Dynamics. Otolaryngol Head Neck Surg. 2015 Aug;153(2):308-9. PMCID: PMC4745903 |
26. Hariri BM, Rhee JS, Garcia GJ. Identifying patients who may benefit from inferior turbinate reduction using computer simulations. Laryngoscope. 2015 Dec;125(12):2635-41. PMCID: PMC4641847 |
27. Patel RG, Garcia GJ, Frank-Ito DO, Kimbell JS, Rhee JS. Simulating the nasal cycle with computational fluid dynamics. Otolaryngol Head Neck Surg. 2015 Feb;152(2):353-60. PMCID: PMC4402730 |
28. Amarante TD, da Silva JK, Garcia GJ. Effects of airway surface liquid height on the kinetics of extracellular nucleotides in airway epithelia. J Theor Biol. 2014 Dec 21;363:427-35. |
29. Frank-Ito DO, Kimbell JS, Laud P, Garcia GJ, Rhee JS. Predicting postsurgery nasal physiology with computational modeling: current challenges and limitations. Otolaryngol Head Neck Surg. 2014 Nov;151(5):751-9. PMCID: PMC4405156 |
30. Kota P, Buchner G, Chakraborty H, Dang YL, He H, Garcia GJM, Kubelka J, Gentzsch M, Stutts MJ, Dokholyan NV. The N-terminal domain allosterically regulates cleavage and activation of the epithelial sodium channel. J Biol Chem. 2014 Aug 15;289(33):23029-23042. PMCID: PMC4132802 |
31. Garcia GJ, Kimbell JS, Frank-Ito DO. In reference to Regional peak mucosal cooling predicts the perception of nasal patency. Laryngoscope. 2014 May;124(5):E210. PMCID: PMC3996834 |
32. Rhee JS, Sullivan CD, Frank DO, Kimbell JS, Garcia GJ. A systematic review of patient-reported nasal obstruction scores: defining normative and symptomatic ranges in surgical patients. JAMA Facial Plast Surg. 2014;16(3):219-25; quiz 232. PMCID: PMC4072745 |
33. Sullivan CD, Garcia GJ, Frank-Ito DO, Kimbell JS, Rhee JS. Perception of better nasal patency correlates with increased mucosal cooling after surgery for nasal obstruction. Otolaryngol Head Neck Surg. 2014 Jan;150(1):139-47. PMCID: PMC3917722 |
34. Kimbell JS, Frank DO, Laud P, Garcia GJ, Rhee JS. Changes in nasal airflow and heat transfer correlate with symptom improvement after surgery for nasal obstruction. J Biomech. 2013 Oct 18;46(15):2634-43. PMCID: PMC3959863 |
35. Herschlag G.J., Garcia G.J.M., Button B., Tarran R., Lindley B., Reinhardt B., Elston T.C., Forest G.; A mechanochemical model for auto-regulation of lung airway surface liquid volume. Journal of Theoretical Biology 325, 42-51, 2013. |
36. Garcia G.J.M., Boucher R.C., Elston T.C.; Biophysical model of ion transport across human respiratory epithelia allows quantification of ion permeabilities. Biophysical Journal 104, 716-726, 2013. |
37. Kimbell J.S., Garcia G.J.M., Frank D.O., Cannon D.E., Pawar S.S., Rhee J.S.; Computed nasal resistance compared with patient-reported symptoms in surgically treated nasal airway passages. American Journal of Rhinology & Allergy 26, e94-e98, 2012. |
38. Rhee J.S., Pawar S.S., Garcia G.J.M., Kimbell J.S.; Towards Personalized Nasal Surgery Using Computational Fluid Dynamics: A Preliminary Report. Archives of Facial Plastic Surgery 13, 305-310, 2011. |
39. Schroeter J.D., Garcia G.J.M., Kimbell J.S.; Effects of Surface Smoothness on Inertial Particle Deposition in Human Nasal Models. Journal of Aerosol Science 42, 52-63, 2011. |
40. Garcia G.J.M., Rhee J.S., Senior B.A., Kimbell J.S.; Septal deviation and nasal resistance: An investigation using virtual surgery and computational fluid dynamics. American Journal of Rhinology & Allergy 24, e46-e53, 2010. |
41. Pawar S.S., Garcia G.J.M., Kimbell J.S., Rhee J.S.; Objective measures in aesthetic and functional nasal surgery: Perspectives on nasal form and function. Facial Plastic Surgery 26, 320-327, 2010. |
42. Schroeter J.D., Garcia G.J.M., Kimbell J.S.; A computational fluid dynamics approach to assess inter-human variability in hydrogen sulfide nasal dosimetry. Inhalation Toxicology 22, 277-286, 2010. |
43. Garcia G.J.M., Kimbell J.S.; Deposition of inhaled nanoparticles in the rat nasal passages: dose to the olfactory region. Inhalation Toxicology 21, 1165-1175, 2009. |
44. Garcia G.J.M., Schroeter J.D., Segal R.A., Stanek J., Foureman G.L., Kimbell J.S.; Dosimetry of nasal uptake of soluble and reactive gases: a first study of inter-human variability. Inhalation Toxicology 21, 607-618, 2009. |
45. Garcia G.J.M., Tewksbury E.W., Wong B.A., Kimbell J.S.; Interindividual variability in nasal filtration as a function of nasal cavity geometry. Journal of Aerosol Medicine and Pulmonary Drug Delivery 22, 139-155, 2009. |
46. Garcia G.J.M., Bailie N., Martins D.A., Kimbell J.S.; Atrophic rhinitis: A CFD study of air conditioning in the nasal cavity. Journal of Applied Physiology 103, 1082-1092, 2007. |
47. Carey S.A., Minard K.R., Trease L.L., Wagner J.G., Garcia G.J.M., Ballinger C.A., Kimbell J.S., Plopper C.G., Corley R.A., Postlethwait E.M., Harkema J.R.; Three-dimensional mapping of ozone-induced injury in the nasal airways of monkeys using magnetic resonance imaging and morphometric techniques. Toxicologic Pathology 35, 27-40, 2007. |
48. Garcia G.J.M., Silva J.K.L.; Interspecific allometry of bone dimensions: A review of the theoretical models. Physics of Life Reviews 3, 188-209, 2006. |
49. Silva J.K.L., Garcia G.J.M., Barbosa L.A.; Allometric scaling laws of metabolism. Physics of Life Reviews 3, 229-261, 2006. |
50. Barbosa L.A., Garcia G.J.M., Silva J.K.L.; The scaling of maximum and basal metabolic rates of mammals and birds. Physica A 359, 547-554, 2006. |
51. Dickman R., Garcia G.J.M.; Absorbing-state phase transitions with extremal dynamics. Physical Review E 71, 066113, 2005. |
52. Garcia G.J.M., Dickman R.; Asymmetric dynamics and critical behavior in the Bak-Sneppen model. Physica A 342, 516-528, 2004. |
53. Garcia G.J.M., Dickman R.; On the thresholds, probability densities, and critical exponents of Bak-Sneppen-like models. Physica A 342, 164-170, 2004. |
54. Garcia G.J.M., Silva J.K.L.; On the scaling of mammalian long bones. Journal of Experimental Biology 207, 1577-1584, 2004. |
55. Garcia G.J.M., Dickman R.; On singular probability densities generated by extremal dynamics. Physica A 332, 318-336, 2004. |
56. Kokshenev V.B., Silva J.K.L., Garcia G.J.M.; Long-bone allometry of terrestrial mammals and the geometric-shape and elastic-force constraints of bone evolution. Journal of Theoretical Biology 224, 551-556, 2003. |
57. Campbell DA, Moghaddam MG, Rhee JS, Garcia GJM. Narrowed Posterior Nasal Airway Limits Efficacy of Anterior Septoplasty. Facial Plast Surg Aesthet Med. 2021;23(1):13-20. PMCID: PMC7876352 |
58. Basu S, Holbrook LT, Kudlaty K, Fasanmade O, Wu J, Burke A, Langworthy BW, Farzal Z, Mamdani M, Bennett WD, Fine JP, Senior BA, Zanation AM, Ebert CS Jr, Kimple AJ, Thorp BD, Frank-Ito DO, Garcia GJM, Kimbell JS. Numerical evaluation of spray position for improved nasal drug delivery. Sci Rep. 2020 Jun 29;10(1):10568. PMCID: PMC7324389 |
59. Le TB, Garcia GJM. Simulating airway collapse in obstructive sleep apnea using fluid-structure interaction methodologies Frontiers in Biomedical Devices, BIOMED - 2018 Design of Medical Devices Conference, DMD 2018. 2018. |
60. Garcia GJM, Mitchell G, Bailie N, Thornhill D, Watterson J, Kimbell JS. Visualization of nasal airflow patterns in a patient affected with atrophic rhinitis using particle image velocimetry Journal of Physics: Conference Series. 1 October 2007;85(1). |
61. da Silva JKL, Garcia GJM, Barbosa LA. Allometric scaling laws of metabolism Physics of Life Reviews. December 2006;3(4):229-261. |
62. Garcia GJM, da Silva JKL. Interspecific allometry of bone dimensions: A review of the theoretical models Physics of Life Reviews. September 2006;3(3):188-209. |
63. Barbosa LA, Garcia GJM, Da Silva JKL. The scaling of maximum and basal metabolic rates of mammals and birds Physica A: Statistical Mechanics and its Applications. 1 January 2006;359(1-4):547-554. |
64. Garcia GJM, Dickman R. Asymmetric dynamics and critical behavior in the Bak-Sneppen model Physica A: Statistical Mechanics and its Applications. 1 November 2004;342(3-4):516-528. |
65. Garcia GJM, Dickman R. On singular probability densities generated by extremal dynamics Physica A: Statistical Mechanics and its Applications. 1 February 2004;332(1-4):318-336. |
66. Garcia GJM, Dickman R. On the thresholds, probability densities, and critical exponents of Bak-Sneppen-like models Physica A: Statistical Mechanics and its Applications. 15 October 2004;342(1-2 SPEC. ISS.):164-170. |
67. Kokshenev VB, Silva JK, Garcia GJ. Long-bone allometry of terrestrial mammals and the geometric-shape and elastic-force constraints of bone evolution. J Theor Biol. 2003 Oct 21;224(4):551-6. |
68. Cherobin GB, Voegels RL, Pinna FR, Gebrim EMMS, Bailey RS, Garcia GJM. Rhinomanometry Versus Computational Fluid Dynamics: Correlated, but Different Techniques. Am J Rhinol Allergy. 2021 Mar;35(2):245-255. |
69. Farnoud A, Tofighian H, Baumann I, Garcia GJM, Schmid O, Gutheil E, Rashidi MM. Large eddy simulations of airflow and particle deposition in pulsating bi-directional nasal drug delivery Physics of Fluids. 1 October 2020;32(10). |
70. Zarandi MAF, Garman K, Rhee JS, Woodson BT, Garcia GJM. Effect of tube length on the buckling pressure of collapsible tubes. Comput Biol Med. 2021 Sep;136:104693. PMCID: PMC8440427 |
71. Vicory J, Garcia GJM, Rhee JS, Enquobahrie A. Toward automatic atlas-based surgical planning for septoplasty. Int J Comput Assist Radiol Surg. 2022 Feb;17(2):403-411. |
72. Hartfield PJ, Janczy J, Sharma A, Newsome HA, Sparapani RA, Rhee JS, Woodson BT, Garcia GJM. Anatomical determinants of upper airway collapsibility in obstructive sleep apnea: A systematic review and meta-analysis. Sleep Med Rev. 2023 Apr;68:101741. PMCID: PMC11493082 |
73. Garcia GJM, Wolf JJ, Campbell DA, Bailey RS, Sparapani RA, Welzig CM, Woodson BT. Mandibular advancement reduces pharyngeal collapsibility by enlarging the airway rather than affecting velopharyngeal compliance. Physiol Rep. 2023 Feb;11(3):e15558. PMCID: PMC9909385 |
74. Venn J, Larkee CE, Garcia GJM, Rayz VL, LaDisa JF Jr. A workflow for viewing biomedical computational fluid dynamics results and corresponding data within virtual and augmented reality environments. Front Med Technol. 2023;5:1096289. PMCID: PMC9996009 |
75. Dey S, Tunio M, Boryc LC, Hodgson BD, Garcia GJM. Quantifying strategies to minimize aerosol dispersion in dental clinics Experimental and Computational Multiphase Flow. 2023. |
76. Dey S, Tunio M, Boryc LC, Hodgson BD, Garcia GJM. Quantifying strategies to minimize aerosol dispersion in dental clinics. Exp Comput Multiph Flow. 2023;5(3):290-303. PMCID: PMC10042415 |
77. Fillion-Robin JC, Bray A, Vicory J, Clipp RB, Garcia GJM, Rhee JS, Enquobahrie A. An Integrated Virtual Surgical Planning System for Nasal Airway Obstruction Proceedings - International Symposium on Biomedical Imaging. 2023;2023-April. |
78. Kimbell JS, Garcia GJM, Schroeter JD, Sheth P, Vallorz EL, Saluja B, Babiskin AH, Tian G, Walenga RL. Nasal steroid spray simulations using measured spray characteristics in healthy and rhinitic nasal passages Journal of Aerosol Science. November 2023;174. |
79. Garcia GJM, Catalano D, Shum A, Larkee CE, Rhee JS. Estimation of Nasal Airway Cross-sectional Area From Endoscopy Using Depth Maps: A Proof-of-Concept Study. Otolaryngol Head Neck Surg. 2024 Jun;170(6):1581-1589. |
80. Lesnick A, Samuels TL, Seabloom D, Wuertz B, Ojha A, Seelig D, Ondrey F, Wiedmann TS, Hogan C, Torii E, Ouyang H, Yan K, Garcia GJM, Bock JM, Johnston N. Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling. Laryngoscope Investig Otolaryngol. 2024 Feb;9(1):e1219. PMCID: PMC10866582 |
81. Hamdan AT, Cherobin GB, Voegels RL, Rhee JS, Garcia GJM. Effects of Mucosal Decongestion on Nasal Aerodynamics: A Pilot Study Otolaryngology - Head and Neck Surgery (United States). 2024. |
82. Hamdan AT, Cherobin GB, Voegels RL, Rhee JS, Garcia GJM. Effects of Mucosal Decongestion on Nasal Aerodynamics: A Pilot Study. Otolaryngol Head Neck Surg. 2024 Jun;170(6):1696-1704. PMCID: PMC11441408 |
83. Hamdan AT, Rungmanee S, Sattaratpaijit N, Shammout N, Woodson BT, Garcia GJM. Impact of posture and CPAP on nasal airflow. Respir Physiol Neurobiol. 2024 Jul;325:104268. |
84. Hamdan AT, Cherobin GB, Voegels RL, Rhee JS, Garcia GJM. Effects of Mucosal Decongestion on Nasal Aerodynamics: A Pilot Study Otolaryngology - Head and Neck Surgery (United States). June 2024;170(6):1696-1704. |
85. Garcia GJM, Woodson BT. Do Patients With Multilevel Collapse Need Multilevel Surgery? JAMA Otolaryngol Head Neck Surg. 2024 Oct 01;150(10):877-878. |
86. Kumar D, Woodson BT, Garcia GJM. Phenotypes of Velopharyngeal Tube Law in Obstructive Sleep Apnea. Otolaryngol Head Neck Surg. 2025 Jan;172(1):336-345. PMCID: PMC11698636 |
87. Dey S, Bock JM, Garcia GJM. Dry powder inhaler deposition in the larynx and the risk of steroid inhaler laryngitis: A computational fluid dynamics study Journal of Aerosol Science. January 2025;183. |
Books, Chapters, and Reviews |
1. Garcia G.J.M., Picher M., Zuo P., Okada S.F., Lazarowski E.R., Button B., Boucher R.C., Elston T.C.; Computational model for the regulation of extracellular ATP and adenosine in airway epithelia. In Purinergic regulation of respiratory diseases (M. Picher and R.C. Boucher, eds.), Chapter 3, Springer Publishing, ISBN-13: 978-9400712164. Subcellular Biochemistry 55, 51-74, 2011. |
Non-Refereed Journal Publications/Original Papers |
1. Garcia G.J.M., Kimbell J.S., Barnum B.T., Cragun M.; Expanding engineering analysis tools to biomedical applications: Using an example of nasal airflow in patients with septal deviations. NAFEMS 2008, 2008. |
2. Tewksbury E.W., Garcia G.J.M., Kimbell J.S., Wong B.A.; Inter-human variability in nasal filtration of inhaled particles among nasal replicas of four healthy individuals. Respiratory Drug Delivery 2008, 767-770, 2008. |
3. Garcia G.J.M., Mitchell G., Bailie N., Thornhill D., Watterson J., Kimbell J.S.; Visualization of nasal airflow patterns in a patient affected with atrophic rhinitis using particle image velocimetry. Journal of Physics: Conference Series 85, 012032, 2007. |
