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CURRICULUM VITAE

John A. Charlson MD
Associate Professor
Department of Medicine
Division of Hematology and Oncology - Medicine

OFFICE ADDRESS:
Clinical Cancer Center
9200 W Wisconsin Ave
Milwaukee, WI 53226

EDUCATION:
09/1989 - 05/1993 B.A., Biology, Luther College, Decorah, IA
09/1995 - 05/1999 M.D., University of Iowa College of Medicine, Iowa City, IA

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
07/1999 - 06/2002 Resident, Internal Medicine, Medical College of Wisconsin Affiliated Hospitals, Milwaukee, WI
07/2005 - 06/2007 Fellow, Division of Neoplastic Diseases, Medical College of Wisconsin Affiliated Hospitals, Milwaukee, WI

FACULTY APPOINTMENTS:
07/2002 - 06/2003 Chief Resident and Instructor, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
07/2003 - 06/2005 Assistant Professor, Department of Medicine, Hospitalist, Medical College of Wisconsin, Milwaukee, WI
07/2007 - Present Assistant Professor, Department of Medicine, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:
07/2002 - Present Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Ave., Milwaukee, WI 53226
07/2002 - 06/2005 Zablocki VA Medical Center, 5000 W. National Ave., Milwaukee, WI 53295

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
American Board of Internal Medicine
09/2002
09/2012
ABIM – Medical Oncology
02/2008
02/2018
 
Licensure
Number Issue DateExpiration
Wisconsin License
42947-020
10/2003
10/2011
 

AWARDS AND HONORS:
05/2004 Outstanding Performance Award, Primary Care Division, Clement Zablocki VA Medical Center, Milwaukee, WI
09/2004 Top Ten Teaching Award, Medical Students, 2003-4, Department of Medicine
09/2004 Top Ten Teaching Award, Residents, 2003-4, Department of Medicine
10/2006 Donald J. Schuenke Cancer Fellowship
12/2008 Top 20 Outpatient Physicians, Froedtert Hospital
09/2009 Best Doctors, 2009-2010, 2010-11

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
10/2006 - Present American Society of Clinical Oncology
10/2008 - Present NSABP
09/2009 - Present Connective Tissue Oncology Society

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Non-Peer Review
Title:
“A Multicenter, Open-Label Single-Arm Study of YONDELIS (trabectedin) for Subjects With Locally Advanced or Metastatic Soft Tissue Sarcoma Who Have Relapsed or Are Refractory to Standard of Care Treatment”
Source:
Johnson & Johnson Pharmaceutical R&D – ET743-SAR-3002
Role:
Principal Investigator, MCW site
Dates:
09/2007 - Present
 
Title:
TDM4370g: A Randomized, Multicenter, Phase III Open-label Study of the Efficacy and Safety of Trastuzumab-MCC-DM1 vs. Capecitabine + Lapatinib in Her-2 Positive Metastatic Breast Cancer
Source:
Genentech
Role:
Principal Investigator, MCW Site
Dates:
06/2009 - Present
 
Prior
Non-Peer Review
Title:
“A Phase I/II Study of IMC-A12 and Doxorubicin in Advanced Soft Tissue Sarcoma”
Source:
Coordinated through University of Chicago Phase II Consortium
Role:
Principal Investigator, MCW site
Dates:
02/2009 - 12/2010
 

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Lab Overutilization and Resident Education, MCW General Internal Medicine Division Meeting, Milwaukee, WI, 03/31/2004
42 y/o man with HIV and rash, Clinicopathologic Case Conference (CPC), Clement J. Zablocki VA Medical Center, Milwaukee, WI, 11/18/2004
Taking Care of Older Patients in Different Settings: A Physician Panel, Panel Discussion, Sponsored by MCW student chapters of ACP, AGS, 03/12/2007
Oncologic Emergencies, Emergency Medicine Grand Rounds, MCW Emergency Medicine Residency, 03/06/2008
Nutrition and Breast Cancer Risk, Women’s Health Event, St. Matthew’s Lutheran Church, Wauwatosa, WI, 01/31/2010
Long-Term Effects of Breast Cancer Treatment, Medicine Grand Rounds, MCW Department of Medicine, 02/26/2010
 
Regional
Poster presentation – Hospitalists Providing Clinical Continuing Education for Inpatient Medical Nurses, Midwest SGIM regional meeting, Chicago, IL, 10/01/2004
Lecture – Transfusion Medicine, Seventeenth Annual Update in Primary Care, Medical College of Wisconsin, Egg Harbor, WI, 10/08/2004
Lecture – Management of Soft Tissue Sarcoma, Gundersen Clinic, La Crosse, WI, 08/13/2009
Lecture – Breast Cancer for Primary Care Physicians, 22nd Annual Update in Primary Care, Medical College of Wisconsin, Egg Harbor, WI, 10/09/2009
Lecture – Primary Care for Cancer Patients, American College of Physicians annual meeting, Wisconsin Dells, WI, 09/11/2010
Lecture – Primary Care Followup after Breast Cancer Treatment, 41st Annual Winter Refresher Course for Family Medicine, Milwaukee, WI, 02/03/2011
 

COMMITTEE SERVICE:
Medical College of Wisconsin
07/2002 - 06/2003 Resident Evaluation Committee, Medical College of Wisconsin
03/2008 - Present Liaison between our division and medicine residency, coordinate resident lecture series and Medicine Grand Rounds speakers, Internal Medicine Resident Curriculum Committee, Medical College of Wisconsin
12/2008 - Present Hematology/Oncology Fellowship Committee, Medical College of Wisconsin
Planning Committee, 8th Biennial MCW Breast Cancer Symposium, Medical College of Wisconsin
 
Hospital
01/2004 - 06/2005 Patient Safety Committee, Froedtert Hospital
01/2007 Internal Review Committee, Pediatric Hematology/Oncology Program
08/2009 I serve as the primary physician representative on this quality improvement working group, implementing efforts to improve quality of care in the cancer center, Cancer Center Working Group Committee, Froedtert Hospital
09/2010 - Present Froedtert Cancer Committee, Froedtert Hospital
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Student Education
07/2002 - 06/2005 JMS Bedside Rounds, ward attending teaching
01/2003 - 05/2003 M1 Interviewing Course
03/2003 - 06/2008 Introduction to Clinical Exam (ICE) Course preceptor
07/2004 - 06/2005 Lecturer, JMS Internal Medicine Core Lecture Series, Topic – Anemia
08/2008 - Present Coordinator and preceptor, M4 Oncology Outpatient Clinic experience
07/2010 - Present Preceptor, M4 Ambulatory Immersion rotation
09/2010 - Present Pathology lecture – M2, Neoplasia Clinical Correlation
 
Resident and Fellow Education
07/2002 - 06/2003 Prepared monthly CPC conferences
07/2002 - 06/2003 Led morning report, prepared Noon Conference lectures
07/2003 - 06/2004 Resident continuity clinic preceptor
09/2003 - 06/2005 Lecturer, Internal Medicine 101 course, topic – Neurologic Examination
07/2004 - 06/2005 Director, Medicine Resident Procedures Rotation Coordinate procedural experiences for senior residents and implement curriculum dealing with issues related to bedside procedures
07/2005 - 06/2007 Monthly lecture to residents on inpatient Oncology service
07/2007 - Present Supervision and teaching as attending physician on Oncology consult and Oncology inpatient services
07/2007 - Present Lecturer, hematology/oncology fellow core curriculum Sarcoma
07/2007 - Present Lecturer, Resident Core Curriculum
08/2008 - Present Coordinator, hematology and oncology lecturers for Resident Academic Half Day
 
Continuing Medical Education
01/2004 - 06/2005 Hospitalist Nursing Education Series A colleague and I provide CME for nursing staff using case-based discussions of inpatient medicine topics
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Neuner J, Smith E, Charlson JA, Pezzin L, Laud P. Medicare Part D low-income subsidy and disparities in breast cancer treatment. J Clin Oncol. 2014 Oct 20;32(30_suppl):2.
2. Klooster B, Rajeev R, Chrabaszcz S, Charlson J, Miura J, Bedi M, Gamblin TC, Johnston F, Turaga KK. Is long-term survival possible after margin-positive resection of retroperitoneal sarcoma (RPS)? J Surg Oncol. 2016 Jun;113(7):823-7.
3. Rajeev R, Patel M, Jayakrishnan TT, Johnston FM, Bedi M, Charlson J, Turaga KK. Retroperitoneal solitary fibrous tumor: surgery as first line therapy. Clin Sarcoma Res. 2015;5:19. PMCID: PMC4551387
4. Berger NG, Silva JP, Mogal H, Clarke CN, Bedi M, Charlson J, Christians KK, Tsai S, Gamblin TC. Overall survival after resection of retroperitoneal sarcoma at academic cancer centers versus community cancer centers: An analysis of the National Cancer Data Base. Surgery. 2018 02;163(2):318-323.
5. Neuner JM, Shi Y, Kong AL, Kamaraju S, Smith EC, Smallwood AJ, Laud PW, Charlson JA. Fractures in a nationwide population-based cohort of users of breast cancer hormonal therapy. J Cancer Surviv. 2018 04;12(2):268-275.
6. Charlson JA, McGinley EL, Nattinger AB, Neuner JM, Pezzin LE. Geographic Variation of Adjuvant Breast Cancer Therapy Initiation in the United States: Lessons From Medicare Part D. J Natl Compr Canc Netw. 2017 12;15(12):1509-1517.
7. Bedi M, King DM, Mendez C, Slawski B, Charlson JA, Hackbarth DA, Neilson JC. Postoperative Day 1 Glucose May Be Associated With Wound Complications in Sarcomas Treated With Preoperative Radiation. Clin Orthop Relat Res. 2018 03;476(3):580-586. PMCID: PMC6260049
8. Johnson AC, Ethun CG, Liu Y, Poultsides G, Howard JH, Bedi M, Charlson J, Tseng J, Roggin KK, Votanopoulos K, Cullinan D, Fields RC, Maithel SK, Cardona K, and other members of the US Sarcoma Collaborative. A novel, simplified, externally validated staging system for truncal/extremity soft tissue sarcomas: An analysis of the US Sarcoma Collaborative database. J Surg Oncol. 2018 Dec;118(7):1135-1141.
9. Wilkinson KH, Ethun CG, Hembrook M, Bedi M, Charlson J, Mogal H, Tsai S, Christians K, Tran TB, Poultsides G, Grignol V, Howard JH, Tseng J, Roggin KK, Chouliaras K, Votanopoulos K, Cullinan D, Fields RC, Weber S, Gamblin TC, Cardona K, Clarke CN. Outcomes of Elderly Patients Undergoing Curative Resection for Retroperitoneal Sarcomas: Analysis From the US Sarcoma Collaborative. J Surg Res. 2019 01;233:154-162.
10. Charlson J. Selection of Patients With Localized Extremity Soft Tissue Sarcoma for Treatment With Perioperative Chemotherapy. Curr Treat Options Oncol. 2018 10 25;19(12):65.
11. Piotrowski JT, Schaefer MB, Charlson JA, Iczkowski KA, Johnson SC. Primary angiosarcoma of the testis with retroperitoneal metastasis. Urol Case Rep. 2018 Nov;21:116-118. PMCID: PMC6168964
12. Yu PY, Beal EW, Hughes TM, Suarez-Kelly LP, Shelby RD, Ethun CG, Tran TB, Poultsides G, Charlson J, Gamblin TC, Tseng J, Roggin KK, Chouliaras K, Votanopoulos K, Krasnick BA, Fields RC, Pollock RE, Grignol V, Cardona K, Howard JH. Perioperative chemotherapy is not associated with improved survival in high-grade truncal sarcoma. J Surg Res. 2018 11;231:248-256.
13. Zarnecki KG, Kristianto J, Charlson J, Wilson B, Blank RD, Shaker JL. Diffuse osteosclerosis as a presentation of recurrent breast cancer: role of endothelin 1. Osteoporos Int. 2019 Aug;30(8):1699-1703.
14. Gannon NP, King DM, Ethun CG, Charlson J, Tran TB, Poultsides G, Grignol V, Howard JH, Tseng J, Roggin KK, Votanopoulos K, Krasnick B, Fields RC, Cardona K, Bedi M. The role of radiation therapy and margin width in localized soft-tissue sarcoma: Analysis from the US Sarcoma Collaborative. J Surg Oncol. 2019 Sep;120(3):325-331.
15. Patel S, von Mehren M, Reed DR, Kaiser P, Charlson J, Ryan CW, Rushing D, Livingston M, Singh A, Seth R, Forscher C, D'Amato G, Chawla SP, McCarthy S, Wang G, Parekh T, Knoblauch R, Hensley ML, Maki RG, Demetri GD. Overall survival and histology-specific subgroup analyses from a phase 3, randomized controlled study of trabectedin or dacarbazine in patients with advanced liposarcoma or leiomyosarcoma. Cancer. 2019 08 01;125(15):2610-2620. PMCID: PMC6771856
16. Dow EN, Piccolo J, Segal EM, Charlson JA. Drug induced periarticular thenar erythema with onycholysis related to nano-albumin bound paclitaxel therapy Cancer Treatment Communications. 2015;4:161-164.
17. Squires MH, Ethun CG, Suarez-Kelly LP, Yu PY, Hughes TM, Shelby RD, Tran TB, Poultsides G, Charlson J, Gamblin TC, Tseng J, Roggin KK, Chouliaras K, Votanopoulos K, Krasnick BA, Fields RC, Pollock RE, Grignol V, Cardona K, Howard JH. Trends in the Use of Adjuvant Chemotherapy for High-Grade Truncal and Extremity Soft Tissue Sarcomas. J Surg Res. 2020 01;245:577-586.
18. . Drug induced periarticular thenar erythema with onycholysis related to nano-albumin bound paclitaxel therapy Cancer Treatment Communications. 2015;4:161-164.
19. Thalji SZ, Tsai S, Gamblin TC, Clarke C, Christians K, Charlson J, Ethun CG, Poultsides G, Grignol VP, Roggin KK, Votanopoulos K, Fields RC, Abbott DE, Cardona K, Mogal H, other members of the US Sarcoma Collaborative. Outcomes of palliative-intent surgery in retroperitoneal sarcoma-Results from the US Sarcoma Collaborative. J Surg Oncol. 2020 Jun;121(7):1140-1147.
20. Bedi M, Ethun CG, Charlson J, Tran TB, Poultsides G, Grignol V, Howard JH, Tseng J, Roggin KK, Chouliaras K, Votanopoulos K, Cullinan D, Fields RC, Cardona K, King DM. Is a Nomogram Able to Predict Postoperative Wound Complications in Localized Soft-tissue Sarcomas of the Extremity? Clin Orthop Relat Res. 2020 03;478(3):550-559. PMCID: PMC7145071
21. Macpherson CF, Stegenga K, Erickson JM, Linder LA, Newman AR, Elswick RK, Charlson J, Thomas S, Ameringer S. Adolescents and Young Adults with Cancer Using a Symptom Heuristics App: Provider Perceptions and Actions. J Adolesc Young Adult Oncol. 2020 10;9(5):579-585. PMCID: PMC7578178
22. Fuller CK, Charlson JA, Dankle SK, Russell TJ. Dramatic improvement of inoperable angiosarcoma with combination paclitaxel and bevacizumab chemotherapy. J Am Acad Dermatol. 2010 Oct;63(4):e83-4.
23. Walters MP, Baynes K, Carrera GF, King DM, Wang D, Charlson J, Zambrano E. Adamantinoma with plasmacytoid features: expanding the spectrum of a diagnostically challenging entity. Ann Diagn Pathol. 2011 Oct;15(5):347-54.
24. Yao X, Hosenpud J, Chitambar CR, Charlson J, Cheng YC. A Phase II Study of Concurrent Docetaxel, Epirubicin and Cyclophosphamide as a Neoadjuvant Chemotherapy Regimen in Patients with Locally Advanced Breast Cancer. J Cancer. 2012;3:145-51. PMCID: PMC3319980
25. Bedi M, King DM, Charlson J, Whitfield R, Hackbarth DA, Zambrano EV, Wang D. Multimodality management of metastatic patients with soft tissue sarcomas may prolong survival. Am J Clin Oncol. 2014 Jun;37(3):272-7.
26. Bedi M, King DM, Shivakoti M, Wang T, Zambrano EV, Charlson J, Hackbarth D, Neilson J, Whitfield R, Wang D. Prognostic variables in patients with primary soft tissue sarcoma of the extremity and trunk treated with neoadjuvant radiotherapy or neoadjuvant sequential chemoradiotherapy. Radiat Oncol. 2013 Mar 14;8:60. PMCID: PMC3621722
27. Bedi M, King DM, Whitfield R, Hackbarth DA, Neilson JC, Charlson JA, Wang D. The effect of smoking and major vein resection on post-therapy lymphedema in soft tissue sarcomas treated with neoadjuvant radiation and limb-salvage surgery. Am J Clin Oncol. 2015 Apr;38(2):184-8.
28. Nattinger AB, Pezzin LE, McGinley EL, Charlson JA, Yen TW, Neuner JM. Patient costs of breast cancer endocrine therapy agents under Medicare Part D vs with generic formulations. Springerplus. 2015;4:54. PMCID: PMC4320689
29. Neuner JM, Kamaraju S, Charlson JA, Wozniak EM, Smith EC, Biggers A, Smallwood AJ, Laud PW, Pezzin LE. The introduction of generic aromatase inhibitors and treatment adherence among Medicare D enrollees. J Natl Cancer Inst. 2015 Aug;107(8). PMCID: PMC4580559
30. Andreason M, Zhang C, Onitilo AA, Engel J, Ledesma WM, Ridolfi K, Kim K, Charlson JC, Wisinski KB, Tevaarwerk AJ. Treatment differences between urban and rural women with hormone receptor-positive early-stage breast cancer based on 21-gene assay recurrence score result. J Community Support Oncol. 2015 May;13(5):195-201. PMCID: PMC4511377
31. Miura JT, Charlson J, Gamblin TC, Eastwood D, Banerjee A, Johnston FM, Turaga KK. Impact of chemotherapy on survival in surgically resected retroperitoneal sarcoma. Eur J Surg Oncol. 2015 Oct;41(10):1386-92.
32. Bedi M, King DM, Hackbarth DA, Charlson JA, Baynes K, Neilson JC. Biopsies in the Community Lead to Postoperative Complications in Soft Tissue Sarcomas. Orthopedics. 2015 Sep;38(9):e753-9.
33. Nattinger AB, Pezzin LE, McGinley EL, Charlson JA, Yen TW, Neuner JM. Erratum to: Patient costs of breast cancer endocrine therapy agents under Medicare Part D vs with generic formulations. Springerplus. 2015;4:531. PMCID: PMC4577495
34. Kashtan MA, Jayakrishnan TT, Rajeev R, Charlson JC, Johnston F, Clark Gamblin T, Turaga KK. Age-based disparities in treatment and outcomes of retroperitoneal rhabdomyosarcoma. Int J Clin Oncol. 2016 Jun;21(3):602-8.
35. Charlson J, Smith EC, Smallwood AJ, Laud PW, Neuner JM. Bone Mineral Density Testing Disparities Among Patients With Breast Cancer Prescribed Aromatase Inhibitors. J Natl Compr Canc Netw. 2016 07;14(7):875-80.
36. Saeed H, King DM, Johnstone CA, Charlson JA, Hackbarth DA, Neilson JC, Bedi M. Preoperative Radiation Therapy Followed by Reexcision May Improve Local Control and Progression-Free Survival in Unplanned Excisions of Soft Tissue Sarcomas of the Extremity and Chest-Wall. Int J Surg Oncol. 2016;2016:5963167. PMCID: PMC5075633
37. Biggers A, Shi Y, Charlson J, Smith EC, Smallwood AJ, Nattinger AB, Laud PW, Neuner JM. Medicare D Subsidies and Racial Disparities in Persistence and Adherence With Hormonal Therapy. J Clin Oncol. 2016 12 20;34(36):4398-4404. PMCID: PMC5455308
 
Books, Chapters, and Reviews
1. Kochar's Handbood of Clinical Medicine for Students, 4th ed., 2009; contributing author for hematology and oncology chapters.
 
Non-Refereed Journal Publications/Original Papers
1. Charlson J, Heinrich T, McCarron RM. How often should women be screened for breast cancer? Current Psychiatry. 2010 Oct;9(10):20-22.
2. Fuller SK, Charlson JA, Dankle SK, Russell TJ. Dramatic improvement of inoperable angiosarcoma with combination paclitaxel and bevacizumab chemotherapy. J Am Acad Dermatol. 2010 Oct, 63(4):e83-4.
3. Walters MP, Baynes K, Carrera GF, King DM, Wang D, Charlson JA, Zambrano E.
4. Adamantinoma with plasmacytoid features: expanding the spectrum of a
5. diagnostically challenging entity. Annals Diagn Pathol. 2010 May 31 (Epub ahead of print).
 
Abstracts
1. Charlson JA, Hedin, T, Sparapani R, Guo C, Nattinger A. Early discontinuation of tamoxifen and aromatase inhibitors (AIs) by postmenopausal women with early-stage breast cancer. ASCO Annual Meeting 2010, abstract 524, poster discussion session.
2. Yao X, Hosenpud JR, Chitambar CR, Charlson JA, Cheng Y. Phase II study of combined docetaxel, epirubicin, and cyclophosphamide as a neoadjuvant chemotherapy regimen in patients with locally advanced breast cancer in a single institution. ASCO Annual Meeting 2010, abstract e11040.
3. Monga V, Skubitz KM, Maliske S, Mott SL, Dietz H, Hirbe AC, Van Tine BA, Oppelt P, Okuno S, Robinson S, O'Connor M, Seetharam M, Attia S, Charlson J, Agulnik M, Milhem M. A Retrospective Analysis of the Efficacy of Immunotherapy in Metastatic Soft-Tissue Sarcomas. Cancers (Basel). 2020 Jul 11;12(7). PMCID: PMC7408640
4. Strong EA, Park SH, Ethun CG, Chow B, King D, Bedi M, Charlson J, Mogal H, Tsai S, Christians K, Tran TB, Poultsides G, Grignol V, Howard JH, Tseng J, Roggin KK, Chouliaras K, Votanopoulos K, Cullinan D, Fields RC, Gamblin TC, Cardona K, Clarke CN. High neutrophil-lymphocyte ratio is not independently associated with worse survival or recurrence in patients with extremity soft tissue sarcoma. Surgery. 2020 10;168(4):760-767.
5. Schulte B, Mohindra N, Milhem M, Attia S, Robinson S, Monga V, Hirbe AC, Oppelt P, Charlson J, Helenowski I, Abbinanti S, Cehic R, Okuno S, Van Tine BA, Agulnik M. Phase II study of pazopanib with oral topotecan in patients with metastatic and non-resectable soft tissue and bone sarcomas. Br J Cancer. 2021 Aug;125(4):528-533. PMCID: PMC8368095
6. Ibrahim EH, Frank L, Baruah D, Arpinar VE, Nencka AS, Koch KM, Muftuler LT, Unal O, Stojanovska J, Rubenstein JC, Brown SA, Charlson J, Gore EM, Bergom C. Value CMR: Towards a Comprehensive, Rapid, Cost-Effective Cardiovascular Magnetic Resonance Imaging. Int J Biomed Imaging. 2021;2021:8851958. PMCID: PMC8147553
7. Ellison C, King DM, Neilson JC, Wooldridge A, Charlson JA, Hackbarth DA, Johnstone C, Bedi M. Preoperative Radiation Performed at a Nonsarcoma Center May Lead to Increased Wound Complications Following Resection in Patients With Soft Tissue Sarcomas. Am J Clin Oncol. 2021 Nov 10.