CURRICULUM VITAE
Jonathan R. Thompson MD
Jonathan R. Thompson MD
Associate Professor
Department of Medicine
Division of Hematology and Oncology - Medicine
Department of Medicine
Division of Hematology and Oncology - Medicine
OFFICE ADDRESS: |
Froedtert Hospital |
9200 W Wisconsin Ave |
Milwaukee, WI 53226 |
EDUCATION: |
2001 - 2005 B.S., Marquette University, Milwaukee, WI |
2006 - 2010 M.D., Medial College of Wisconsin, Milwaukee, WI |
2016 - 2018 Master of Science - Clinical and Translational Science, Medical College of Wisconsin, Milwaukee, WI |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
2010 - 2013 Resident, Medicine, Medical College of Wisconsin Affiliated Hospitals, Milwaukee, WI 53226 |
2013 - 2014 Chief Resident, Medicine, Medical College of Wisconsin, Milwaukee, WI 53226 |
2014 - 2017 Fellow, Medicine, Hematology/Oncology, Medical College of Wisconsin Affiliated Hospitals, Milwaukee, WI 53226 |
FACULTY APPOINTMENTS: |
07/01/2017 - 06/30/2024 Assistant Professor, Medicine, Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI 53226 |
07/01/2019 - 06/30/2021 Hematology/Oncology Fellow Clinic Supervisor, Medicine, Hematology/Oncology, Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI |
07/01/2024 - Present Associate Professor, Medicine, Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI 53226 |
EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: |
07/01/2018 - Present M4 Medical Student Course Director - Hematology/Oncology Consults, Medical College of Wisconsin |
07/01/2018 - Present M4 Medical Student Course Director - Inpatient Neoplastic Diseases, Medical College of Wisconsin |
07/01/2018 - Present M4 Medical Student Course Director - Outpatient Hematology/Oncology, Medical College of Wisconsin |
RESEARCH ADMINISTRATIVE APPOINTMENTS: |
07/01/2021 - Present Vice Chair - Early Phase Disease Oriented Team, Hematology/Oncology, Medical College of Wisconsin |
SPECIALTY BOARDS AND CERTIFICATION: |
Board Certified | Issue Date | Expiration |
Internal Medicine Board Certification | 2013 | 2023 |
Hematology | 12/20/2017 | 12/20/2027 |
Medical Oncology | 12/20/2017 | 12/20/2027 |
AWARDS AND HONORS: |
05/09/2013 Research Award, Medical College of Wisconsin Affiliated Hospitals |
07/01/2016 - 06/30/2017 Mazie Froedtert Willms & Sue Froedtert Cancer Fellow at Froedtert Hospital, Froedtert and the Medical College of Wisconsin |
05/17/2017 Research and Quality Award, Medical College of Wisconsin Affiliated Hospitals |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
2014 - Present American Society of Clinical Oncology (Member) |
2015 - Present International Association for the Study of Lung Cancer (Member) |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Ad-Hoc Reviewer |
02/19/2019 Clinical Lung Cancer |
10/08/2020 Hematology Oncology & Stem Cell Therapy |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
07/01/2020 - Present Committee Member, Immuno-Oncology Committee, Alliance Oncology |
01/01/2023 - Present Sub-committee member, NRG Oncology Immunotherapy Sub-committee |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
Regional |
Updates in Early Stage Lung Cancer, Best of ASCO: Milwaukee, Hyatt Regency - Milwaukee, 06/29/2024 - 06/30/2024 |
Controversies in Metastatic, EGFR-mutated, Non-small Cell Lung Cancer, OncLive State of the Science Summit: Lung Cancer, Milwaukee, WI, 10/08/2024 |
Community Discussion: Conversations with Scientists. Immunology: The Best Offense is a Good Defense, Medical College of Wisconsin |
Local |
The Immunotherapy Revolution for Lung Cancer, American Lung Association LUNG FORCE Expo, Sheraton Milwaukee - Brookfield, WI, 11/14/2018 |
Green Bay Oncology Grand Rounds, Green Bay, WI, 05/10/2019 |
Recent Immunotherapy Advances In Non-small Cell Lung Cancer, Wisconsin Association of Hematology and Oncology Annual Meeting, Milwaukee, WI, 08/23/2019 |
Jonathan Thompson, Management of Immune-Related Adverse Events, Medical College of Wisconsin Advances in Hematology & Oncology Virtual Symposium, Virtual, 02/06/2021 |
Immunotherapy Toxicity Management, MCW Updates In Lung Cancer Symposium, Italian Community Center, 08/20/2022 |
It takes a village: Immunotherapy Toxicity at MCW, MCW Department of Medicine Grand Rounds, 02/24/2023 |
Impact of Immunotherapy on Survivorship, 3rd Annual Oncology Survivorship in Primary Care, Medical College of Wisconsin, 10/04/2024 |
New Cancer Therapies, New Side Effects: Engaging PCPs to Optimize Patient Care, MCW Annual Updates In Primary Care, Lake Geneva, WI, 10/10/2024 |
Updates and Controversies in Lung Cancer: 2024 in Year in Review, Advances in Hematology/Oncology MCW Fall Symposium, KI Convention Center, Green Bay, WI, 10/26/2024 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
10/2017 Member, Intern Selection Committee, Medicine, Medical College of Wisconsin |
07/01/2018 - Present Founding Member, IRB Committee #6, Medical College of Wisconsin |
09/2018 - Present Member, Fellow Selection Committee, Hematology/Oncology, Medicine, Medical College of Wisconsin |
04/2020 - Present Thoracic Disease Team Liaison, NCTN LAPS Committee, Hematology/Oncology, Medicine, Medical College of Wisconsin |
04/01/2021 - Present Committee Member, MCW Precision Oncology Workgroup on Training, Education and Mentorship, Hematology/Oncology, Medicine, Medical College of Wisconsin |
MCW TEACHING ACTIVITIES: |
Medical Student Education |
07/01/2017 - Present M1Clinical Apprenticeship Preceptor |
08/17/2017 - 09/07/2017 Molecules to Cells Course Clinician Preceptor |
Resident and Fellow Education |
08/09/2017 Resident Academic Half Day Oncologic Emergencies Lecture |
05/01/2018 - Present Annual Oncology Fellow lecture on Immunotherapy and Lung Cancer |
07/01/2018 - 07/01/2020 Fellowship Clinic Preceptor VA |
07/02/2018 Fellow Orientation Lecture Oncologic Emergencies |
08/15/2018 Resident Academic Half Day Oncologic Emergencies Lecture |
01/08/2019 Pulmonary and Critical Care Fellowship Grand Rounds |
02/12/2021 Pulmonary and Critical Care Fellowship Grand Rounds |
03/02/2022 Division of Rheumatology Invited Lecture: Rheumatologic cancer immunotherapy-related adverse events |
04/14/2023 Pulmonary and Critical Care Fellowship Grand Rounds |
Community/Lay Public |
10/30/2018 Community Discussion: Conversations with Scientists. Immunology: The Best Offense is a Good Defense |
EXTRAMURAL TEACHING: |
Resident and Fellow Education |
05/10/2019 St. Joe's Residency Program, Resident lecture on Lung Cancer |
Community/Lay Public |
09/11/2018 Froedtert and the Medical College of Wisconsin, Community Education Sesion: Cancer Immunotherapy: CAR T-cells and Beyond |
PROGRAMMATIC DEVELOPMENTS: |
Clinical Programs |
09/01/2018 - Present Founding Member, Virtual, real-time brain metastasis tumor board (N.I.M.B.L.E.), Medical College of Wisconsin |
10/01/2020 - Present Founder and Leader of Immunotherapy Toxicity Team |
COMMUNITY SERVICE ACTIVITIES: |
12/02/2019 Spoke with students at Whitnall Middle School about careers in healthcare at Career Day |
11/19/2022 Guest Speaker at SDS SHINE Event - Community outreach event designed to engage the Milwaukee African American Community on important cancer topics held at St. Martin De Porres Catholic Church. |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Wu HE, Thompson J, Sun HS, Leitermann RJ, Fujimoto JM, Tseng LF. Nonopioidergic mechanism mediating morphine-induced antianalgesia in the mouse spinal cord. J Pharmacol Exp Ther. 2004 Jul;310(1):240-6. |
2. Wu HE, Thompson J, Sun HS, Terashvili M, Tseng LF. Antianalgesia: stereoselective action of dextro-morphine over levo-morphine on glia in the mouse spinal cord. J Pharmacol Exp Ther. 2005 Sep;314(3):1101-8. |
3. Hillard CJ, Ho WS, Thompson J, Gauthier KM, Wheelock CE, Huang H, Hammock BD. Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. Br J Pharmacol. 2007 Nov;152(5):691-8. PMCID: PMC2190024 |
4. Ho WS, Patel S, Thompson JR, Roberts CJ, Stuhr KL, Hillard CJ. Endocannabinoid modulation of hyperaemia evoked by physiologically relevant stimuli in the rat primary somatosensory cortex. Br J Pharmacol. 2010 Jun;160(3):736-46. PMCID: PMC2931572 |
5. Cornell RF, Hari P, Zhang MJ, Zhong X, Thompson J, Fenske TS, Horowitz MM, Komorowski R, Palmer J, Pasquini MC, Rizzo JD, Saber W, Thomas M, Drobyski WR. Divergent effects of novel immunomodulatory agents and cyclophosphamide on the risk of engraftment syndrome after autologous peripheral blood stem cell transplantation for multiple myeloma. Biol Blood Marrow Transplant. 2013 Sep;19(9):1368-73. |
6. Pingali SR, Jewell SW, Havlat L, Bast MA, Thompson JR, Eastwood DC, Bartlett NL, Armitage JO, Wagner-Johnston ND, Vose JM, Fenske TS. Limited utility of routine surveillance imaging for classical Hodgkin lymphoma patients in first complete remission. Cancer. 2014 Jul 15;120(14):2122-9. |
7. Thompson JR, Menon SP, Dy GK. Tyrosine kinase inhibitors for EGFR- and ALK-mutated non-small cell lung cancer ADMET and DMPK. 1 October 2016;4(3):186-211. |
8. Thompson JR, Zhu J, Kilari D, Wang L. Applications of Extracellular RNAs in Oncology. Mol Diagn Ther. 2017 Feb;21(1):1-11. |
9. Thompson J, Yin Z, D'Souza A, Fenske T, Hamadani M, Hari P, Rizzo JD, Pasquini M, Saber W, Shah N, Shaw BE, Shahir K, Banerjee A, Drobyski WR. Etanercept and Corticosteroid Therapy for the Treatment of Late-Onset Idiopathic Pneumonia Syndrome. Biol Blood Marrow Transplant. 2017 Nov;23(11):1955-1960. |
10. Thompson JR, Menon SP. Liquid Biopsies and Cancer Immunotherapy. Cancer J. 2018;24(2):78-83. |
11. Du M, Thompson J, Fisher H, Zhang P, Huang CC, Wang L. Genomic alterations of plasma cell-free DNAs in small cell lung cancer and their clinical relevance. Lung Cancer. 2018 Jun;120:113-121. |
12. Conroy JM, Pabla S, Nesline MK, Glenn ST, Papanicolau-Sengos A, Burgher B, Andreas J, Giamo V, Wang Y, Lenzo FL, Bshara W, Khalil M, Dy GK, Madden KG, Shirai K, Dragnev K, Tafe LJ, Zhu J, Labriola M, Marin D, McCall SJ, Clarke J, George DJ, Zhang T, Zibelman M, Ghatalia P, Araujo-Fernandez I, de la Cruz-Merino L, Singavi A, George B, MacKinnon AC, Thompson J, Singh R, Jacob R, Kasuganti D, Shah N, Day R, Galluzzi L, Gardner M, Morrison C. Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors. J Immunother Cancer. 2019 Jan 24;7(1):18. PMCID: PMC6346512 |
13. Pabla S, Conroy JM, Nesline MK, Glenn ST, Papanicolau-Sengos A, Burgher B, Hagen J, Giamo V, Andreas J, Lenzo FL, Yirong W, Dy GK, Yau E, Early A, Chen H, Bshara W, Madden KG, Shirai K, Dragnev K, Tafe LJ, Marin D, Zhu J, Clarke J, Labriola M, McCall S, Zhang T, Zibelman M, Ghatalia P, Araujo-Fernandez I, Singavi A, George B, MacKinnon AC, Thompson J, Singh R, Jacob R, Dressler L, Steciuk M, Binns O, Kasuganti D, Shah N, Ernstoff M, Odunsi K, Kurzrock R, Gardner M, Galluzzi L, Morrison C. Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients. J Immunother Cancer. 2019 Feb 01;7(1):27. PMCID: PMC6359802 |
14. Brown SA, Zaharova S, Mason P, Thompson J, Thapa B, Ishizawar D, Wilkes E, Ahmed G, Rubenstein J, Sanchez J, Joyce D, Kalyanaraman B, Widlansky M. Pandemic Perspective: Commonalities Between COVID-19 and Cardio-Oncology. Front Cardiovasc Med. 2020;7:568720. PMCID: PMC7746643 |
15. Jain PV, Thompson J, Sheinin Y. Resected cytokeratin-negative small cell lung carcinoma. BMJ Case Rep. 2023 Apr 03;16(4). PMCID: PMC10083812 |
16. Thapa B, Ahmed G, Szabo A, Kamgar M, Kilari D, Mehdi M, Menon S, Daniel S, Thompson J, Thomas J, George B. Comprehensive genomic profiling: Does timing matter? Front Oncol. 2023;13:1025367. PMCID: PMC9971445 |
17. Simone CB 2nd, Serebrenik AA, Gore EM, Mohindra P, Brown SL, Wang D, Chetty IJ, Vujaskovic Z, Menon S, Thompson J, Fine G, Kaytor MD, Movsas B. Multicenter Phase 1b/2a Clinical Trial of Radioprotectant BIO 300 Oral Suspension for Patients With Non-Small Cell Lung Cancer Receiving Concurrent Chemoradiotherapy. Int J Radiat Oncol Biol Phys. 2024 Feb 01;118(2):404-414. |
18. Borghaei H, de Marinis F, Dumoulin D, Reynolds C, Theelen WSME, Percent I, Gutierrez Calderon V, Johnson ML, Madroszyk-Flandin A, Garon EB, He K, Planchard D, Reck M, Popat S, Herbst RS, Leal TA, Shazer RL, Yan X, Harrigan R, Peters S, SAPPHIRE Investigators. SAPPHIRE: phase III study of sitravatinib plus nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. Ann Oncol. 2024 Jan;35(1):66-76. |
19. Stratton N, Thompson J. Prolonged Cancer Control With Adagrasib in Patients With Metastatic, KRAS<sup>G12C</sup>-Mutated NSCLC After Sotorasib-Induced Hepatotoxicity: A Case Report JTO Clinical and Research Reports. April 2024;5(4). |
20. Ellison C, Martens M, Alvarez Argote J, Benz S, Currey A, Johnstone C, Klawikowski S, Livingston K, Longo JM, Menon S, Ortiz de Choudens S, Puckett L, Retseck J, Shukla M, Thompson J, Gore E. High-Grade Pneumonitis Events in Patients With Unresectable, Locally Advanced NSCLC Treated With Definitive Chemoradiation Followed by Adjuvant Durvalumab JTO Clinical and Research Reports. December 2024;5(12). |
21. Bo AY, Cheng YC, George B, Kilari D, Thompson JR, Jorns JM. Online Portal Use of Pathology Reports in Patients With Solid Tumors. Arch Pathol Lab Med. 2024 Dec 26. |
Abstracts |
1. Jonathan R Thompson, Carlos Arce-Lara, Aniko Szabo, Smitha Menon. Microbiome & Immunotherapy: Antibiotic Use Is Associated with Inferior Survival for Lung Cancer Patients Receiving PD-1 Inhibitors World Conference on Lung Cancer 2017. Abstract 693. |
2. Ravi K Narra, Arun K Singavi, Jonathan Thompson, Smitha Menon, James Thomas, Carolyn Oxencis, Matthew Riese, Paul Ritch, Deepak Kilari, Aniko Szabo, Ben George. Application of comprehensive genomic profiling (CGP) to predict therapeutic response to immune checkpoint inhibitors (ICI). AACR Annual Meeting 2018. |
3. Chad Glisch, Aniko Szabo, Jonathan R Thompson, Smitha Menon, Jay Patel. Sarcopenia is Associated with Metastatic Burden and is a Negative Prognostic Factor in Metastatic Non-Small Cell Lung Cancer World Conference on Lung Cancer 2018. . |
4. Jonathan R Thompson, Carlos Arce-Lara, Smitha Menon. Use of Immune Checkpoint Inhibitors (ICIs) in Patients with Refractory Non-Small Cell Lung Cancer (NSCLC) and Poor Performance Status (PS) World Conference on Lung Cancer 2018. . |
5. Enriqueta Felip, Paal Brunsvig, Nuria Vinolas, Santiago Ponce Aix, Enric Carcereny Costa, Manuel Dómine Gomez, Jose Manuel Trigo Perez, Edurne Arriola, Rosario Garcia Campelo, James F. Spicer, Jonathan Robert Thompson, Ana Laura Ortega Granados, Robert J Holt, Katherine Lorens, James B. Lorens, Muhammad Shoaib, Abdul Siddiqui, Emmett V. Schmidt, Michael Jon Chisamore, Matthew Krebs. A phase II study of bemcentinib (BGB324), a first-in-class highly selective AXL inhibitor, with pembrolizumab in pts with advanced NSCLC: OS for stage I and preliminary stage II efficacy J Clin Oncol. J Clin Oncol 37, 2019 (suppl:abstr 9098). |
6. Griffiths C, Menon S, Thompson JR Durvalumab Consolidation Following Chemoradiation for Unresectable Non-Small Cell Lung Cancer: A "Real-World" Experience. World Conference on Lung Cancer 2020, Singapore. |
7. Krebs MG, Helland A, Carcereny Costa E, Arriola Apperibay E, Domine Gomez M, Trigo Perez J, Thompson J, Strauss J, Ortega Granados AL, Felip E, Schmidt E, Chisamore M, Madeleine N, Rayford A, Lorens K, Siddiqui A, Gabra H, Nauiyal J, Micklem D, Lorens J, Spicer J. A Phase II Study of the Oral Selective AXL Inhibitor Bemcentinib with Pembrolizumab in Patients with Advanced NSCLC. World Conference on Lung Cancer 2020, Singapore. |
8. Fernando Santos-Pinheiro, Joseph Bovi, Wendy Peltier, Jennifer Connelly, Wade Mueller, Michael Straza, Lindsay Puckett, Marianne Crabb, Julianne Leuck, Nathan Zwagerman, Jonathan Thompson, Christopher Schultz, Jennifer Lindstedt, Kimberly Roller-Voigt, Ariel Nelson, Sarah Bichler, Alexandra Leutenegger, Tracy Erlitz, Carolyn Brausch, Hina Saeed, Dustin Hahn, Fernando Santos-Pinheiro. QOLP-01. OUTCOME ASSESSMENT OF MULTIDISCIPLINARY BRAIN TUMOR BOARD MEETING RECOMMENDATIONS FOR BRAIN METASTASIS: IS THERE A GAP? Neuro-Oncology. Volume 22, Issue Supplement_2, November 2020, Page ii174. |
9. Joseph Bovi, Jennifer Lindstedt, Fernando Santos-Pinheiro, Wade Mueller, Straza Michael, Lindsay Puckett, Jonathan Thompson, Ariel Nelson, Wendy Peltier, Carolyn Brausch, Tracy Erlitz, Heather Meerstein, David Atkinson, Marianne Crabb, Julianne Leuck, Kimberly Roller-Voigt, Christopher Schultz. INNOVATIVE USE OF A CUSTOM MOBILE APPLICATION (APP) BY A BRAIN METASTASES PROGRAM FACILITATES MULTIDISCIPLINARY MANAGEMENT OF PATIENTS AND DECREASED LENGTH OF HOSPITAL STAY (LOS) Neuro-Oncology Advances. Volume 2, Issue Supplement_2, August 2020, Page ii7. |
10. Joe R, Matsumura Y, Siddiqui A, Foulks J, Beg M, Thompson J, Yamamoto N, Spira A, Sarantopoulos J, Melear J, Lou Y, Lebedinsky C, Li J, Watanabe A, Warner S. The AXL inhibitor, TP-0903, reverses EMT and shows activity in non-small cell lung cancer preclinical models European Journal of Cancer. October 2022;174:S57-S58. |
