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Jonathan R. Thompson MD
Assistant Professor
Department of Medicine
Division of Hematology and Oncology - Medicine

Froedtert Hospital
9200 W Wisconsin Ave
Milwaukee, WI 53226

2001 - 2005 B.S., Marquette University, Milwaukee, WI
2006 - 2010 M.D., Medial College of Wisconsin, Milwaukee, WI
2016 - 2018 Master of Science - Clinical and Translational Science, Medical College of Wisconsin, Milwaukee, WI

2010 - 2013 Resident, Medicine, Medical College of Wisconsin Affiliated Hospitals, Milwaukee, WI 53226
2013 - 2014 Chief Resident, Medicine, Medical College of Wisconsin, Milwaukee, WI 53226
2014 - 2017 Fellow, Medicine, Hematology/Oncology, Medical College of Wisconsin Affiliated Hospitals, Milwaukee, WI 53226

07/01/2017 - Present Assistant Professor, Medicine, Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI 53226

Board Certified
Issue DateExpiration
Internal Medicine Board Certification
Medical Oncology
05/09/2013 Research Award, Medical College of Wisconsin Affiliated Hospitals
07/01/2016 - 06/30/2017 Mazie Froedtert Willms & Sue Froedtert Cancer Fellow at Froedtert Hospital, Froedtert and the Medical College of Wisconsin
05/17/2017 Research and Quality Award, Medical College of Wisconsin Affiliated Hospitals

2014 - Present American Society of Clinical Oncology (Member)
2015 - Present International Association for the Study of Lung Cancer (Member)

07/01/2020 - Present Committee Member, Immuno-Oncology Committee, Alliance Oncology

Peer Review
Oligosaccharide supplementation among Clostridium difficile Hematology-Oncology Patients
Clinical and Translational Science Institute Southeast Wisconsin
Silvia Munoz-Price
07/15/2019 - 07/14/2020
Direct Funds:
Peer Review
Phase I Study of the Safety of Irradiated Autologous iPSC-based vaccines to elicit Anti-Tumor Responses in Patients with Lung Neoplasias
Medical College of Wisconsin Cancer Center Pilot Award
Ivor Benjamin
12/01/2018 - 11/30/2019
Direct Funds:

The Immunotherapy Revolution for Lung Cancer, American Lung Association LUNG FORCE Expo, Sheraton Milwaukee - Brookfield, WI, 11/14/2018
Green Bay Oncology Grand Rounds, Green Bay, WI, 05/10/2019
Recent Immunotherapy Advanced In Non-small Cell Lung Cancer, Wisconsin Association of Hematology and Oncology Annual Meeting, Milwaukee, WI, 08/23/2019

Medical College of Wisconsin
07/01/2018 - Present IRB Member, IRB Committee #6, Medical College of Wisconsin
09/01/2018 - Present Member, Brain Metastasis Service Line, Medical College of Wisconsin

Community/Lay Public
10/30/2018 Community Discussion: Conversations with Scientists. Immunology: The Best Offense is a Good Defense
Medical Student Education
07/01/2017 - 12/31/2017 M2 Clinical Apprenticeship Preceptor
08/17/2017 - 09/07/2017 Molecules to Cells Course Clinician Preceptor
2018 - Present Course Director - Outpatient and Inpatient M4 Hematology/Oncology Elective
Resident and Fellow Education
08/09/2017 Resident Academic Half Day Oncologic Emergencies Lecture
07/01/2018 - Present Fellowship Clinic Preceptor VA
07/02/2018 Fellow Orientation Lecture Oncologic Emergencies
08/15/2018 Resident Academic Half Day Oncologic Emergencies Lecture

Community/Lay Public
09/11/2018 Froedtert and the Medical College of Wisconsin, Community Education Sesion: Cancer Immunotherapy: CAR T-cells and Beyond

Refereed Journal Publications/Original Papers
1. Wu HE, Thompson J, Sun HS, Leitermann RJ, Fujimoto JM, Tseng LF. Nonopioidergic mechanism mediating morphine-induced antianalgesia in the mouse spinal cord. J Pharmacol Exp Ther. 2004 Jul;310(1):240-6.
2. Hillard CJ, Ho WS, Thompson J, Gauthier KM, Wheelock CE, Huang H, Hammock BD. Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. Br J Pharmacol. 2007 Nov;152(5):691-8. PMCID: PMC2190024
3. Wu HE, Thompson J, Sun HS, Terashvili M, Tseng LF. Antianalgesia: stereoselective action of dextro-morphine over levo-morphine on glia in the mouse spinal cord. J Pharmacol Exp Ther. 2005 Sep;314(3):1101-8.
4. Ho WS, Patel S, Thompson JR, Roberts CJ, Stuhr KL, Hillard CJ. Endocannabinoid modulation of hyperaemia evoked by physiologically relevant stimuli in the rat primary somatosensory cortex. Br J Pharmacol. 2010 Jun;160(3):736-46. PMCID: PMC2931572
5. Cornell RF, Hari P, Zhang MJ, Zhong X, Thompson J, Fenske TS, Horowitz MM, Komorowski R, Palmer J, Pasquini MC, Rizzo JD, Saber W, Thomas M, Drobyski WR. Divergent effects of novel immunomodulatory agents and cyclophosphamide on the risk of engraftment syndrome after autologous peripheral blood stem cell transplantation for multiple myeloma. Biol Blood Marrow Transplant. 2013 Sep;19(9):1368-73.
6. Pingali SR, Jewell SW, Havlat L, Bast MA, Thompson JR, Eastwood DC, Bartlett NL, Armitage JO, Wagner-Johnston ND, Vose JM, Fenske TS. Limited utility of routine surveillance imaging for classical Hodgkin lymphoma patients in first complete remission. Cancer. 2014 Jul 15;120(14):2122-9.
7. Jonathan R. Thompson, Smitha P. Menon, Grace K. Dy. Tyrosine kinase inhibitors for EGFR- and ALK-mutated non-small cell lung cancer ADMET & DMPK. ADMET & DMPK 4(3)(2016) 186-211.
8. Thompson JR, Zhu J, Kilari D, Wang L. Applications of Extracellular RNAs in Oncology. Mol Diagn Ther. 2017 02;21(1):1-11.
9. Thompson J, Yin Z, D'Souza A, Fenske T, Hamadani M, Hari P, Rizzo JD, Pasquini M, Saber W, Shah N, Shaw BE, Shahir K, Banerjee A, Drobyski WR. Etanercept and Corticosteroid Therapy for the Treatment of Late-Onset Idiopathic Pneumonia Syndrome. Biol Blood Marrow Transplant. 2017 Nov;23(11):1955-1960.
10. Thompson JR, Menon SP. Liquid Biopsies and Cancer Immunotherapy. Cancer J. 2018 Mar/Apr;24(2):78-83.
11. Du M, Thompson J, Fisher H, Zhang P, Huang CC, Wang L. Genomic alterations of plasma cell-free DNAs in small cell lung cancer and their clinical relevance. Lung Cancer. 2018 06;120:113-121.
12. Conroy JM, Pabla S, Nesline MK, Glenn ST, Papanicolau-Sengos A, Burgher B, Andreas J, Giamo V, Wang Y, Lenzo FL, Bshara W, Khalil M, Dy GK, Madden KG, Shirai K, Dragnev K, Tafe LJ, Zhu J, Labriola M, Marin D, McCall SJ, Clarke J, George DJ, Zhang T, Zibelman M, Ghatalia P, Araujo-Fernandez I, de la Cruz-Merino L, Singavi A, George B, MacKinnon AC, Thompson J, Singh R, Jacob R, Kasuganti D, Shah N, Day R, Galluzzi L, Gardner M, Morrison C. Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors. J Immunother Cancer. 2019 01 24;7(1):18. PMCID: PMC6346512
13. Pabla S, Conroy JM, Nesline MK, Glenn ST, Papanicolau-Sengos A, Burgher B, Hagen J, Giamo V, Andreas J, Lenzo FL, Yirong W, Dy GK, Yau E, Early A, Chen H, Bshara W, Madden KG, Shirai K, Dragnev K, Tafe LJ, Marin D, Zhu J, Clarke J, Labriola M, McCall S, Zhang T, Zibelman M, Ghatalia P, Araujo-Fernandez I, Singavi A, George B, MacKinnon AC, Thompson J, Singh R, Jacob R, Dressler L, Steciuk M, Binns O, Kasuganti D, Shah N, Ernstoff M, Odunsi K, Kurzrock R, Gardner M, Galluzzi L, Morrison C. Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients. J Immunother Cancer. 2019 02 01;7(1):27. PMCID: PMC6359802
1. Jonathan R Thompson, Carlos Arce-Lara, Aniko Szabo, Smitha Menon. Microbiome & Immunotherapy: Antibiotic Use Is Associated with Inferior Survival for Lung Cancer Patients Receiving PD-1 Inhibitors World Conference on Lung Cancer 2017. Abstract 693.
2. Ravi K Narra, Arun K Singavi, Jonathan Thompson, Smitha Menon, James Thomas, Carolyn Oxencis, Matthew Riese, Paul Ritch, Deepak Kilari, Aniko Szabo, Ben George. Application of comprehensive genomic profiling (CGP) to predict therapeutic response to immune checkpoint inhibitors (ICI). AACR Annual Meeting 2018.
3. Chad Glisch, Aniko Szabo, Jonathan R Thompson, Smitha Menon, Jay Patel. Sarcopenia is Associated with Metastatic Burden and is a Negative Prognostic Factor in Metastatic Non-Small Cell Lung Cancer World Conference on Lung Cancer 2018. .
4. Jonathan R Thompson, Carlos Arce-Lara, Smitha Menon. Use of Immune Checkpoint Inhibitors (ICIs) in Patients with Refractory Non-Small Cell Lung Cancer (NSCLC) and Poor Performance Status (PS) World Conference on Lung Cancer 2018. .
5. Enriqueta Felip, Paal Brunsvig, Nuria Vinolas, Santiago Ponce Aix, Enric Carcereny Costa, Manuel Dómine Gomez, Jose Manuel Trigo Perez, Edurne Arriola, Rosario Garcia Campelo, James F. Spicer, Jonathan Robert Thompson, Ana Laura Ortega Granados, Robert J Holt, Katherine Lorens, James B. Lorens, Muhammad Shoaib, Abdul Siddiqui, Emmett V. Schmidt, Michael Jon Chisamore, Matthew Krebs. A phase II study of bemcentinib (BGB324), a first-in-class highly selective AXL inhibitor, with pembrolizumab in pts with advanced NSCLC: OS for stage I and preliminary stage II efficacy J Clin Oncol. J Clin Oncol 37, 2019 (suppl:abstr 9098).
6. Sherry-Ann Brown, Svetlana Zaharova, Peter Mason, Jonathan Thompson, Bicky Thapa, David Ishizawar, Erin Wilkes, Gulrayz Ahmed, Jason Rubenstein, Joyce Sanchez, David Joyce, Balaraman Kalyanaraman, Michael Widlansky. Pandemic Perspective: Commonalities Between COVID-19 and Cardio-Oncology Frontiers in Cardiovascular Medicine. Front. Cardiovasc. Med., 04 December 2020.

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