CURRICULUM VITAE
Kathleen M. Schmainda PhD
Kathleen M. Schmainda PhD
Professor
Department of Biophysics
Department of Biophysics
OFFICE ADDRESS: |
Medical Education Building |
8701 Watertown Plank Rd |
Milwaukee, WI 53226 |
EDUCATION: |
09/1981 - 05/1986 BSE (Summa Cum Laude), Marquette University, Milwaukee, WI |
09/1986 - 05/1989 MSEE, Massachusetts Institute of Technology, Cambridge, MA |
05/1989 - 09/1993 PhD, Harvard University/Massachusetts Institute of Technology, Cambridge, MA |
1989 - 1993 PhDEE, Massachusetts Institute of Technology, Cambridge, MA |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
09/1993 - 12/1995 Postdoctoral Fellow in MRI, Department of Radiology, Harvard / Massachusetts General Hospital NMR Center, Charlestown, MA |
FACULTY APPOINTMENTS: |
1996 - 2002 Assistant Professor, Biophysics Research Institute, Medical College of Wisconsin, Milwaukee, WI |
1996 - Present Adjunct Professor, Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI |
1998 - 2002 Assistant Professor, Department of Radiology, Medical College of Wisconsin, Milwaukee, WI |
2002 - 2008 Associate Professor, Departments of Radiology (primary) & Biophysics (secondary), Medical College of Wisconsin, Milwaukee, WI |
2008 - 2018 Professor, Departments of Radiology (primary) & Biophysics (secondary), Medical College of Wisconsin, Milwaukee, WI |
2016 - 2018 Robert C. Olson, MD, Professor in Radiology Endowment Professorship, Medical College of Wisconsin, Milwaukee, WI |
2018 - Present Professor, Departments of Biophysics (primary) & Radiology (secondary), Medical College of Wisconsin, Milwaukee, WI |
ADMINISTRATIVE APPOINTMENTS: |
1998 - 2004 Co-Director, Functional Imaging Program, Marquette University & Medical College of Wisconsin, Milwaukee, WI |
2008 - 2012 Research Director, Translational Brain Tumor Research Program, Medical College of Wisconsin, Milwaukee, WI |
2010 - 2014 Director, Cancer Imaging Program, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
2010 - 2017 Vice-Chair, Radiology Research, Department of Radiology, Medical College of Wisconsin, Milwaukee, WI |
RESEARCH ADMINISTRATIVE APPOINTMENTS: |
1984 OTHER RESEARCH EMPLOYMENT: Co-op Engineer, [Co-Op Engineer, Electronics Design Laboratory (1st term), Special Products Design Engineering Unit (2nd term)], General Electric Medical Systems, Waukesha, WI |
1985 - 1987 OTHER RESEARCH EMPLOYMENT: Computer Programmer, Veteran's Administration Medical Center, Milwaukee, WI |
1998 - 2000 OTHER RESEARCH EMPLOYMENT: Consultant, IGC/Medical Advances, Milwaukee, WI |
2004 - Present Co-Founder, Prism Clinical Imaging, Inc., Elm Grove, WI |
2007 - Present Founder, Imaging Biometrics LLC, Elm Grove, WI |
AWARDS AND HONORS: |
1981 - 1986 Academic Scholarship, Marquette University, Milwaukee, WI |
1981 - 1986 Dean's List (all semesters), Marquette University, Milwaukee, WI |
1982 - 1983 Outstanding Sophomore in Engineering Award, Marquette University, Milwaukee, WI |
1985 - 1986 ALPHA ETA MU BETA, Biomedical Engineering Honor Society, Marquette University, Milwaukee, WI |
1985 - 1987 TAU BETA PI, All Engineering Honor Society, Marquette University, Milwaukee, WI |
1986 Engineering convocation speaker, Marquette University, Milwaukee, WI |
1986 Summa Cum Laude Graduate, Marquette University, Milwaukee, WI |
1986 High Scholastic Honors in Biomedical Engineering, Marquette University, Milwaukee, WI |
1986 High Scholastic Honors in Computer Medical Applications, Marquette University, Milwaukee, WI |
1987 - 1988 Outstanding Woman of America |
1989 - 1990 Sterling Winthrop Fellowship, Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA |
1993 - 1994 Gillette Fellowship, Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA |
1996 - 1998 Medical Engineering Fellowship, Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA |
1997 Finisher, Big Sur International Marathon |
1998 Milwaukee Business Journal's 40 under 40 |
1998 Finisher, Milwaukee Lakefront Marathon, Qualifier for Boston Marathon |
04/1999 Magna Cum Laude Poster Award, American Society of Neuroradiology Annual Meeting |
1999 Finisher, Boston Marathon |
04/2001 Scientific Exhibit Gold Medal, 101st Annual Scientific Meeting at American Roentgen Ray Society, Seattle, WA |
05/2004 Young Investigator Award to Dr. Schmainda's graduate student, Kevin Bennett, 12th Annual Meeting of International Society of Magnetic Resonance in Medicine, Kyoto, Japan |
05/2004 First Place Poster Award, Cancer and Spectroscopy Category to Dr. Schmainda's graduate student, Christopher C. Quarles, 12th Annual Meeting of International Society of Magnetic Resonance in Medicine, Kyoto, Japan |
06/2004 Summa Cum Laude Poster Award, 42nd Annual Meeting of American Society of Neuroradiology Meeting |
2004 Summa Cum Laude, American Society of Neuroradiology Meeting |
2004 First Place Poster Award, Cancer Imaging and Spectroscopy, International Society of Magnetic Resonance in Medicine Meeting |
2004 Young Investigator Moore Award, International Society of Magnetic Resonance in Medicine Meeting |
2006 Bayer Best Paper Award, 45th Annual Meeting of American Society of Neuroradiology |
06/2007 Bayer Best Paper Award to Dr. Schmainda's graduate student, Eric Paulson, 45th Annual Meeting of American Society of Neuroradiology Meeting, Chicago |
05/2008 3rd Place Poster Award to Dr. Schmainda's graduate student, Douglas Prah, 16th Annual Meeting of International Society of Magnetic Resonance in Medicine, Toronto |
05/2009 1st Place Poster Award in Cancer Imaging to Dr. Schmainda's post-doctoral fellow, Dr. Elllingson, 17th Annual Meeting for International Society of Magnetic Resonance in Medicine, Honolulu, HI |
05/2010 Young Investigator
Moore Award, International Society of Magnetic Resonance in Medicine Meeting |
05/2012 Merit Award, International Society of Magnetic Resonance in Medicine Meeting |
05/2013 One of five most-cited papers published in Journal of Magnetic Resonance in Imaging in 2010 (announced at 2013 ISMRM meeting), International Society of Magnetic Resonance in Medicine |
05/2013 Summa Cum Laude Merit Award, International Society of Magnetic Resonance in Medicine |
2013 ISMRM Summa Cum Laude Merit Award, International Society of Magnetic Resonance in Medicine Meeting |
04/2016 Elected to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows (induction ceremony on Monday April 4, 2016 at the National Academy of Sciences), Washington, DC |
09/2016 - 2018 Robert C Olson MD Endowed Chair in Radiology, Medical College of Wisconsin, Milwaukee, WI (relinquished endowment in order to switch primary appointment to Biophysics) |
11/2016 Distinguished Investigator of the Academy of Radiology Research, Radiological Society of North America, Chicago, IL |
2016 College of Fellows, American Institute for Medical and Biological Engineering (AIMBE) |
08/28/2019 Nominated as 1 of 15 semifinal candidates nominated for “Scientific Paper of the Year” in the 2019 edition of the Minnies, AuntMinne.com (a large comprehensive community website for medical imaging professionals worldwide) |
08/28/2019 Nominated as 1 of 16 semifinal candidates for “Most Influential Radiology Researcher” in the 2019 edition of the Minnies, AuntMinne.com |
09/05/2019 Dean’s Award for Clinical and Translational Research 2019, Medical College of Wisconsin |
11/20/2019 Outstanding Graduate School Educator 2018-2019, MCW Graduate School of Biomedical Sciences |
04/2020 Elected as a Fellow of the International Society of Magnetic Resonance in Medicine |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
1990 - Present International Society of Magnetic Resonance in Medicine |
1997 Society of Biomedical Engineering |
1998 - 2001 Peter Favre Forum for Catholic Professionals |
1999 - 2012 Wisconsin MIT Alumni Club |
2009 - Present Society of Neuro-Oncology |
2010 - Present Radiologic Society of North America |
2016 - Present University Faculty for Life (Board Member) |
2016 - Present American Institute for Medical and Biological Engineering (AIMBE) (Fellow) |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorship |
1996 - Present Doody Book Publishers |
1996 - Present Medical Physics (Associate Editor) |
Editorial Board |
2017 - Present Tomography |
Journal Review |
1996 - Present Magnetic Resonance in Medicine |
1996 - Present Radiology |
1996 - Present Circulation |
1996 - Present Journal of Magnetic Resonance Imaging |
1996 - Present Journal of Physiology |
1996 - Present Radiographics |
1996 - Present NMR in Biomedicine |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
10/1998 Session Chair, Biomedical Engineering Society Annual Meeting, Cleveland, OH |
04/2000 Session moderator "Quantitative relaxation techniques", International Society of Magnetic Resonance in Medicine, 8th Annual Meeting, Denver, CO |
2000 - Present Abstract Referee, International Society of Magnetic Resonance in Medicine Annual Meetings |
07/2001 Invited Panelist, NCI SBIR review meeting: "Development of novel imaging technologies (R21/SBIR)", Washington, DC |
2001 - 2005 NIH Grant Referee, NIH/NCI Study Section, "Development of In Vivo Imaging and Bioengineering Research", Washington, DC |
2001 - 2002 Ad Hoc Grant Referee, Massachusetts Prostate Cancer Research Grants Program |
05/2002 Session Moderator, International Society of Magnetic Resonance in Medicine, 10th Annual Meeting, Honolulu, HI |
08/2003 NIH Invited Working Group Participant, NIH/NIBIB: "Biomedical entrepreneurial science working group", Washington, DC |
2004 NIH Grant Referee, NIH/MABS (Modeling and analysis of biological systems) Study Section, Washington, DC |
2004 Advisory Committee Member, Head and Neck Subcommittee, ACRIN (American College of Radiology Imaging Network), Washington, DC (The committee's role is to develop and recommend imaging studies for multi-center clinical trials.) |
08/2007 Technical Advisory Committee Member, ACRIN (American College of Radiology Imaging Network) Neuroimaging Core Lab, Washington, DC (The purpose of this committee is to serve as a repository of expertise in helping to define and implement the core lab functions that can help to further ACRIN multi-center clinical trials.) |
2007 - 2008 Grant Referee, NIH/NCI Clinical Studies Special Emphasis Panel, NCI P01 Program, Washington, DC |
2008 Member, Technical Advisory Committee, STIR (Stroke Imaging Repository Consortium), (The purpose of STIR is to create an international consortium of investigators and a repository of source MRI and CT images tow and clinical research methods of image-based stroke research.) |
2008 NIH Grant Referee, NIH/MABS (Modeling and analysis of biological systems) Study Section, Washington, DC |
02/2009 NIH Grant Referee, NIH/NCI, Tumor Biology Study Section, Washington, DC |
03/2009 NIH Grant Referee, NIH/NCI, In Vivo Imaging and Bioengineering Research Review Panel, San Diego, CA |
2009 - 2013 Charter Member, NIH Grant Referee, NIH/NCI Developmental Therapeutics Study Section (DT), Oncology 2 – Translational Clinical (OTC) IRG |
2009 External Advisor, University of Michigan Program Project Grant External Advisory Committee, Ann Arbor, MI |
2010 - 2018 NIH/NCI Grant Referee, NIH/NCI Quantitative Imaging Network (U01, U24, UG3/UH3) |
01/2011 NIH Diffusion Imaging Workshop, Invited speaker and Chair for "Technical Breakout: Image Processing and Analysis Section", Washington, DC |
07/30/2013 NIH/NCI Grant Referee, Division of Translational and Clinical Sciences (DTCS), Surgical Sciences, Biomedical Imaging and Bioengineering (SBIB) IRG, ZRG1 SBIB-Z (03) Study Section |
2013 Member, Search Committee for Chair of Biomedical Engineering, Marquette University, Milwaukee, WI |
02/20/2014 NIH/NCI Grant Referee, Division of Translational and Clinical Sciences (DTCS), Surgical Sciences, Biomedical Imaging and Bioengineering (SBIB) IRG, ZRG1 SBIB-Z (58), Image-Guided Drug Delivery in Cancer, Teleconference Review |
11/13/2014 NIH/NCI Grant Referee, Division of Translational and Clinical Sciences (DTCS), Surgical Sciences, Biomedical Imaging and Bioengineering (SBIB) IRG, ZRG1 SBIB-Z (55), Bioengineering Research Partnerships (BRP) R01 review panel |
03/12/2015 NIH/NCI Grant Referee, Surgical Sciences, Biomedical Imaging and Bioengineering IRG (SBIB), Division of Translational Clinical Sciences, Center for Scientific Review, Image-Guided Drug Delivery in Cancer, ZRG1 SBIB-Z (58) R Study Section |
06/2015 Reviewer, NIH Fellowship Review Panel: F-Awards (F32 Ruth L. Kirstein National Research Service Awards (NRSA): F30, F31, F32, and F33 Fellowship applications review |
07/08/2015 NIH Fellowship Grants Referee, Surgery, Anesthesiology and Trauma Study Section, Review of Pre-Doc (F30, F31) and post-doc (F32) applications, ZRG1 F15-P fellowship special emphasis panel |
09/02/2015 Invited Participant, Marquette University College of Engineering "Thought Leaders Council" |
2015 - 2018 Member, MRI Value Add Committee, International Society of Magnetic Resonance in Medicine |
2015 - 2017 Member, Alliance Neuro-Oncology Imaging Subcommittee |
2015 - 2016 Member, NIH/NCI Site Review Committee, NCI Cancer Center Site Review, January 2016, University of Arizona |
2015 - Present Member, Jumpstarting Brain Tumor Coalition, DSC-MRI Standardization Committee |
2015 - Present Member, RSNA, QIBA (Quantitative Imaging Biomarker Alliance) |
2015 - Present MRI Biomarker Committee: DSC-MRI Subcommittee, QIBA (Quantitative Imaging Biomarker Alliance) |
11/02/2016 - 02/17/2017 Invited Participant, Marquette University College of Engineering “Thought Leaders Council” |
2016 - Present Board Member, University Faculty for Life |
10/20/2017 NIH Grant Referee, Study Section Review Panel, SRO: Nadeem Khan |
02/14/2018 NIH/NCI Grant Referee, Special Emphasis Panel, ZCA1 TCRB-V (M1), Quantitative Imaging |
05/30/2018 NIH/NCI Grant Referee, Surgical Sciences, Biomedical Imaging and Bioengineering (SBIB) IRG, Early Phase Clinical Trials in Imaging and Biomarkers for Early Detection of Aggressive Cancer” Study Section |
02/21/2019 - 02/22/2019 NIH/NCI Grant Referee, Surgical Sciences, Biomedical Imaging and Bioengineering IRB, EITA, BMIT-B), San Diego, CA |
06/24/2019 - 06/25/2019 NIH/NCI Grant Referee, Academic-Industrial Partnership (AIP) Review Panel, ZRG1 SBIB-Q57, Bethesda, MD |
05/06/2020 - 05/08/2020 Reviewer, NIH/NCI Cancer Center Site Review site visit team (SRO: Caterina Bianco, MD, PhD) |
06/10/2020 - 06/12/2020 Reviewer, NIBIB Biomedical Technology Resource Centers (BTRC) P41 Review Panel. (SRO: Dennis J. Hlasta, PhD) |
INTERNATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
04/2001 Invited Panelist, NCI: "High Field MR (1.5T and up) in Oncology: Strategic frontiers in cancer diagnosis", Glasgow, Scotland |
05/2007 Session Moderator, International Society of Magnetic Resonance in Medicine, 15th Annual Meeting, Berlin, Germany |
2015 - 2018 MRI Value Add Committee, International Society of Magnetic Resonance in Medicine |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
Local |
Speaker, MRI in Cardiac Perfusion Imaging, Graduate Seminar Series, Biophysics Research Institute, MCW, Milwaukee, WI, 02/1996 |
Speaker, Functional MRI: How it Works, Scientific Fundraising Presentation, MCW Council Meeting, University Club, Milwaukee, WI, 1997 |
Speaker, Diagnostic Functional MRI, M-2 Medical Engineering Interest Group, MCW, Milwaukee, WI, 1999 |
Speaker, Functional MRI evaluation of tumor angiogenesis, Seminar Series, Department of Pharmacology, MCW, Milwaukee, WI, 1999 |
Speaker, Functional MRI: How it works, Young Presidents Organization (Hosted by MCW), Milwaukee, WI, 1999 |
Speaker, Evaluation of brain tumor angiogenesis using MRI, Functional Imaging Research Center, MCW, Milwaukee, WI, 05/2000 |
Speaker, The role of MRI in targeted gene therapy, Focus meeting to explore the future imaging possibilities in the area of molecular and genetic imaging with GE Medical Systems, MCW, Milwaukee, WI, 06/2000 |
Speaker, Using Functional MRI for the evaluation of therapies in mice, Pediatric Hematology & Oncology Research Meeting, MCW, Milwaukee, WI, 2000 |
Speaker, Diffusion MRI: Fundamentals and Applications, Functional Imaging Research Center, MCW, Milwaukee, WI, 05/2001 |
Speaker, Using MRI for the evaluation of brain tumor angiogenesis, Grand Rounds, Department of Neurosurgery, MCW, Milwaukee, WI, 08/2001 |
Speaker, Functional MRI of Brain Tumor Angiogenesis, Board Meeting, MCW, Milwaukee, WI, 06/2002 |
Speaker, Using MRI for the evaluation of brain tumor angiogenesis, Biophysics Research Institute, MCW, Milwaukee, WI, 10/2002 |
Speaker, Using MRI for the evaluation of brain tumor angiogenesis, Grand Rounds, Department of Neurology, MCW, Milwaukee, WI, 10/2002 |
Speaker, Tumor and Molecular Imaging, External Advisory Meeting, MCW Cancer Center, MCW, Milwaukee, WI, 02/2003 |
Speaker, Imaging of tumor angiogenesis, Seminar Series, Multidisciplinary Breast Cancer Research Group, MCW, Milwaukee, WI, 04/2003 |
Speaker, Innovative Imaging Tracks Brain Tumors, Cancer Media Day Program at MCW, Milwaukee, WI, 11/04/2003 |
Speaker for 7th grade girls, What does a scientist do?, American Association of University Women (AAUW) - Menomonee Falls Branch, WI, 12/2003 |
Speaker, New Directions for MR Imaging of Brain Cancer, Graduate Seminar Series, Department of Biophysics, MCW, Milwaukee, WI, 01/2004 |
Speaker, Image-guided therapy: an emerging technology, Invited Speaker for Visiting Russian Scientists at MCW, Milwaukee, WI, 08/2005 |
Speaker, Making MRI 'Real' in the Clinic, Seminar Series, Department of Biophysics, MCW, Milwaukee, WI, 02/2006 |
Speaker, Brain MRI Perfusion Imaging: Current Status and Future Goals, Grand Rounds, Department of Neurosurgery, MCW, Milwaukee, WI, 12/14/2007 |
Speaker, The Latest and Greatest in MRI Perfusion Imaging of Brain Tumors, Department of Radiology, MCW, Milwaukee, WI, 07/25/2008 |
Speaker, DSC-MRI Perfusion Imaging in Brain Tumors: Current Status & Future Trends at MCW and Nationally, Department of Radiology Research Seminar Series, MCW, Milwaukee, WI, 10/15/2015 |
Speaker, MRI Guided Treatment and Surveillance of Brain Tumors, requested presentation to Dr. Berger, Larson Grand Rounds, Visiting Professor, Department of Neurosurgery, MCW, Milwaukee, WI, 10/30/2015 |
Speaker, MRI of Placenta, Maternal Fetal Medicine Research Meeting, 01/20/2016 |
Speaker, “Diagnosis and Treatment Monitoring of Brain Tumors Using Perfusion and Diffusion MRI: Past, Present and Future Efforts at MCW and Nationally”, Department of Neurosurgery Grand Rounds, MCW, Milwaukee, WI, 03/09/2018 |
Teacher, SPARCC (Student Centered Pipeline to Advance Research in Cancer Careers) to improve diversity and culturally responsive care in the field of cancer research, MCW, Milwaukee, WI, 2019 - 2021 |
Seminar Speaker, Children's Wisconsin, Milwaukee, WI, 02/2020 |
Regional |
Speaker, FMRI in Muscle Perfusion, Research Meeting, General Electric Medical Systems, Waukesha, WI, 1996 |
Speaker, Characterization of FMRI contrast mechanisms, Department of Biomedical Engineering, Marquette University, Milwaukee, WI, 1997 |
Speaker, Functional MRI: How it Works, Meeting of Entrepreneurs, Milwaukee Exchange Club, Milwaukee, WI, 1998 |
Interview, Applications of Echo Planar Imaging to Disease Evaluation, Tip-TV Educational Video Series, General Electric Medical Systems, Waukesha, WI, 1999 |
Speaker, Utility of simultaneously-acquired gradient-echo and spin-echo cerebral blood volume and morphology maps for the evaluation of brain tumors, Department of Medical Physics, University of Wisconsin, Madison, WI, 1999 |
Speaker, What Does an Assistant Professor Do?, Undergraduate Seminar Series, Department of Biomedical Engineering, Marquette University, Milwaukee, WI, 02/2001 |
Speaker, New directions for MR imaging of brain cancer, Seminar, General Electric Medical Systems, Waukesha, WI, 08/2003 |
Lecturer, Understanding functional magnetic resonance imaging (fMRI), Tip-TV Educational Video Series, General Electric Medical Systems, Waukesha, WI, 08/2004 |
Live Interview, Breast Cancer Research at MCW, WITI-Channel 6 Wake-Up News, Milwaukee, WI, 03/2006 |
Speaker, Introduction to MRI, Graduate Seminar Series, Department of Physics, University of Wisconsin, Milwaukee, W, 02/2007 |
Speaker, Leaders, Women Entrepreneur's Dinner, Conference for Women, University Club, Milwaukee, WI, 03/2009 |
Speaker, Wisconsin Women in Science Luncheon Series, Wisconsin Club, Milwaukee, WI, 06/2011 |
Speaker, Challenges of a Pro-Life Scientist, Legatus, Catholic Business Professionals, Milwaukee, WI, 08/2012 |
Speaker, Strategies in translational imaging research: working at the interface of tumors and technology, Biomedical Engineering Seminar, Joint Biomedical Engineering Seminar Series (Marquette University, MCW, University of Wisconsin-Milwaukee), Milwaukee, WI, 02/20/2015 |
Visiting Professor, Towards a Consensus DSC-MRI Approach for the Evaluation of Brain Tumors, Radiology Grand Rounds, University of Wisconsin, Madison, WI, 10/11/2018 |
National |
Course Lecturer, Functional Regional Perfusion using MRI, SPIE Imaging Meeting, San Diego, CA, 1998 |
Panelist, NIH/NCI Conference of the Joint Working Group on Quantitative In Vivo Functional Imaging in Oncology, Washington D.C., 1999 |
Speaker, Role of Functional MRI in the Evaluation of Disease, Howard Hughes Institute, University of Iowa, Iowa City, IA, 03/2000 |
Speaker, Utility of Simultaneous GE/SE MRI for the Evaluation of Brain Tumor Angiogenesis, Seminar, Beth Israel - Deaconess Hospital, Harvard University, Boston, MA, 06/2000 |
Speaker, The role of MRI perfusion imaging for the evaluation of brain cancer, 12th Annual Rachidian Society Meeting, Kona, Hawaii, 02/2004 |
Speaker, Contrast-agent perfusion imaging, Gordon Conference, Lewiston, ME, 07/2004 |
Speaker, rCBV Imaging, Seminar, Johns Hopkins University, Baltimore, MD, 07/2005 |
Lecturer, Steady-state and first-pass contrast agent methods to evaluate cerebral blood volume (CBV) vascular morphology and permeability, Morning Categorical Course, International Society of Magnetic Resonance in Medicine, Seattle, WA, 04/2006 |
Course Lecturer, DSC MRI Quantification of CBV in Presence of BBB Leakage, Advanced in Neuroimaging Course, Massachusetts General Hospital / Harvard Medical School, Boston, MA, 09/25/2007 |
Speaker, Measurement of rCBV in normal brain and brain tumor depends on the choice of DSC acquisition and analysis method, ACRIN (American College of Radiology Imaging Network) Annual Meeting, Washington D.C., 09/28/2007 |
Speaker, New Directions for MR Imaging of Brain Cancer, Arizona State University, Phoenix, AZ, 03/13/2008 |
Speaker, Current Status and Future Directions for MRI Perfusion Imaging in Primary Brain Tumors, Barrows Neurological Institute, Phoenix, AZ, 03/14/2008 |
Speaker, Diffusion Image Processing and Analysis, NIH Diffusion Imaging Workshop, Washington D.C., 02/2011 |
Speaker, MR DSC Perfusion Imaging in Brain Tumors, University of Alabama, Birmingham, AL, 07/2011 |
Speaker, Development of Perfusion and Diffusion MRI Biomarkers for the Evaluation of Brain Tumors, Northwestern University, Chicago, IL, 08/2011 |
Lecturer, Perfusion MRI in Glioma" for Sunrise Educational Session, Society of Neuro-Oncology Annual Meeting, San Jose, CA, 11/2011 |
Debate Panelist, Multimodality/Multiparametric MR of Cancer, ISMRM MR in Cancer Study Group, Salt Lake City, UT, 05/2013 |
Speaker, Role of Advanced Physiologic MRI for the Evaluation of Brain Tumor Response to Therapies: Part I, St. Louis NMR Discussion Group, Washington University, St. Louis, MO, 10/2013 |
Speaker, Perfusion & Diffusion MRI for Brain tumors: current Status Promise & Challenges: Part II, St. Louis NMR Discussion Group, Washington University, St. Louis, MO, 12/2013 |
Speaker, Utero-placental perfusion, Workshop, Human Placenta Project: Placental Structure and Function in Real Time, National Institute of Child Health and Development, Washington D.C., 05/27/2014 |
Speaker, Dynamic susceptibility contrast, Workshop on standards for quantitative MRI, National Institute of Standards (NIST), Boulder, CO, 07/14/2014 |
Visitor/Speaker, Barrow Neurological Institute, Phoenix, AZ, 10/12/2014 |
Speaker, Frye-Halloran (Brain Tumor) Symposium, Hosted by Neurosurgical Oncology, Massachusetts General Hospital, Boston, MA, 04/09/2015 |
Visiting Professor, Mayo Clinic, Phoenix, AZ, 09/14/2015 |
Speaker, Update on Advanced MRI (DSC-MRI) Standardization Efforts, Alliance NeuroOncology, Chicago, IL, 11/06/2015 |
Speaker, DSC-MRI in measuring relative cerebral blood volume for early response to bevacizumab in patients with recurrent glioblastoma, Alliance for Clinical Trials in Oncology, Chicago, IL, 05/13/2017 |
Speaker, DSC-MRI in measuring relative cerebral blood volume for early response to bevacizumab in patients with recurrent glioblastoma, Alliance for Clinical Trials in Oncology, Chicago, IL, 05/13/2017 |
Speaker, Assessment of Treatment Response in Brain Tumors: Perfuson and Diffusion MRI, Rebecca D. Considine Research Institute & Akron Children’s Hospital, Akron University Department of Biomedical Engineering, Akron, OH, 02/22/2018 |
Visiting Professor, “Assessment of Treatment Response in Brain Tumors: Perfusion and Diffusion MRI”, Akron Children’s Hospital & University of Akron, Cleveland, OH, 02/22/2018 |
Presented the EAF151 trial via web-ex to all QIN executive members and their teams, National Cancer Institute Quantitative Imaging Network, 09/17/2018 |
Fellow, AIMBE Fellows Advocacy Day AIMBE (American Institute of Medical and Biologic Engineers), Fellows participated in meetings with US congressmen to advocate for an increase in NIH funding for biomedical research, Washington, DC, 02/2019 |
International |
Panelist, Higher Field MR (1.5T and up) in Oncology, National Cancer Institute Workshop, Glasgow, Scotland, 04/2001 |
Panelist, National Cancer Institute Workshop on “Higher Field MR (1.5T and up) in Oncology, Glasgow, Scotland, 04/2001 |
Lecturer, Weekend Educational Course, International Society of Magnetic Resonance in Medicine, Berlin, Germany, 05/2007 |
Lecturer, Current status of DSC-MRI quantification with BBB leakage, International Society of Magnetic Resonance in Medicine Perfusion/Diffusion Workshop, Salvador, Brazil, 07/2007 |
Lecturer, Advanced MRI Perfusion Methods, Weekend Educational Course, International Society of Magnetic Resonance in Medicine, Stockholm, Sweden, 05/2010 |
Speaker, Perfusion and Diffusion Biomarkers for the Evaluation of Brain Cancer Diagnosis & Treatment, ISMRM Scientific Workshop: Magnetic Resonance of Cancer Gone Multimodal (19-22 February 2013), Valencia, Spain, 02/2013 |
Course Speaker, Quantitative Imaging and Modeling Course at the 2014 ISMRM Annual Meeting, Milan, Italy, 05/2014 |
Course Speaker, Other Methods: DSC-MRI, BOLD, ASL, MRS” given in ISMRM Annual Meeting weekend course on “Imaging for Cancer, International Society of Magnetic Resonance in Medicine 25th Annual Meeting & Exhibition, Honolulu, HI, 04/22/2017 |
Course Speaker, Diffusion and Perfusion Imaging Protocols for Glioma, ISMRM Annual Meeting weekend course on "Brain Cancer from Diagnosis to Treatment", Honolulu, HI, 04/2017 |
Course Speaker, Other Methods: DSC-ASL MRI, BOLD MRS, ISMRM Annual Meeting weekend course on "Imaging for Cancer", Honolulu, HI, 04/2017 |
Speaker, Theoretical Principles of DSC-MRI Perfusion Imaging, AMRINO (Advanced MRI in Neuro-Oncology) Annual Meeting, London, England, 07/20/2018 |
Speaker, “Theoretical Principles of DSC-MRI Perfusion Imaging”, AMRINO (Advanced MRI for NeuroOncology) Conference, London, England, 07/2018 |
Keynote Speaker, European Union, COST Initiative, Malta, 12/2019 |
Speaker, “Dynamic Susceptibility Contrast MRI: Update on Clinical Applications in Brain Tumors”, International Society of Magnetic Resonance in Medicine, Perfusion Study Group, Virtual Meeting with an audience of over 300 international attendees, 03/05/2020 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
1996 - 1998 Supervisor, 3T MRI Technologist |
1996 Poster Judge, Graduate Student Day |
1996 Member, Technical Standards Committee |
1997 - 1999 Chair, Faculty Library Committee |
1997 - 2007 Chair, MR Research Safety Committee |
05/14/1998 Designated MCW Representative, Speaker and Tour Guide Roger Fitzsimonds, Chairman, CEO & Director of Firstar Bank |
11/10/1998 Designated MCW Representative, Speaker and Tour Guide for Dr. Nancy Zimpher, UWM Chancellor |
11/1999 Presenter, MCW Research Foundation Board of Directors Meeting |
12/1999 Designated MCW Representative, Speaker and Tour Guide for Beijing visitors (International Journal of Medical Devices, Chinese Publishing House) |
1999 - 2004 Chair, Keck Research MRI Pilot Studies Committee |
01/21/2000 Designated MCW Representative, Speaker and Tour Guide for Emil Soika, President and CEO, Criticare Systems, Waukesha, WI |
2000 - Present Designated Representative, Speaker, and Tour Guide for Various Potential Philanthropists for MCW |
2000 - 2004 Member, Graduate Studies Council |
02/2002 Designated MCW Representative, Speaker and Tour Guide for U.S. President George W. Bush, (The tour was cancelled at the last minute due to national security concerns regarding a liquid nitrogen tank near tour area.) |
09/2002 Designated MCW Representative, Speaker and Tour Guide for Wisconsin State Senator Green Bay, WI |
10/30/2003 Designated MCW Representative, Speaker and Tour Guide for Joseph Hogan, President & CEO, General Electric Medical Systems |
11/04/2003 Designated MCW Representative, Speaker and Tour Guide for invited speaker for Cancer Media Day Program at MCW |
2003 Member, Ad Hoc Advisory Committee – Imaging Center |
2003 - Present Member, Cancer Center Grants Review Committee |
2004 - 2006 Member, Biomedical and Biotechnology Center Grant Awards Committee |
08/2005 Designated MCW Representative, Speaker and Tour Guide for invited speaker for Visiting Russian Scientists, (Special American Business Internship Training Program and the U.S. Department of Commerce) held at MCW |
2005 - 2007 Member, Advancing a Healthier Wisconsin Research Grants Review Committee |
2007 - 2008 Member, Search Committee, FIRC (Functional Imaging Research Center) Director |
2007 - 2009 Member, Institutional Animal Care and Use Committee |
2008 - 2012 Member, Search Committee, vanDeuren Breast Cancer Chair |
2011 - 2014 Program Co-Leader, Cancer Imaging Program, Cancer Center |
2012 - Present Faculty Mentor, Medical Students for Life Club |
2013 - 2016 Member, Women's Faculty Council |
2014 - 2015 Member, Search Committee, Chair, Department of Neurology |
2014 - Present Reviewer, MCW Cancer Center Grant Reviews (July 2014, January 2018, February 2018, April 2018) |
2014 - 2015 Member, MCW Working Group to Develop Inter Institutional Biomedical Engineering Program with other engineering programs in Southeast Wisconsin |
2015 Member, Marquette – MCW Biomedical Engineering Faculty Recruitment Subcommittee |
2015 Member, Marquette – MCW Biomedical Engineering Advisory Committee |
2016 - 2018 Member, Marquette-MCW Biomedical Engineering, Founding Chair Search Committee |
2017 - 2018 Member, Marquette-MCW Biomedical Engineering, Research Committee |
2019 - Present Group Facilitator, Clinical and Translational Research Pathway for Medical Students |
MEDICAL COLLEGE TEACHING ACTIVITIES: |
Medical Student Education |
1998 - Present Lecturer presenting "MR Fundamentals" and "MR Imaging" for the Basic Science in Radiology course offered each summer. |
02/10/2014 - Present Lecturer, "Perfusion MRI" for "Introduction to Medical Imaging" course offered to M4 medical students. |
Resident and Fellow Education |
1998 - Present Lecturer presenting "MR Physics" for the Radiology Resident course offered each summer. |
02/04/2014 - Present Speaker to Radiology Residents, "Today's Research is Tomorrow's Clinical Practice," Department of Radiology. |
Continuing Medical Education |
1997 - 2008 Lecturer for "Fundamentals of FMRI" which is part of the MCW Functional Magnetic Resonance Imaging Course which is an ongoing course, given each Fall and Spring, to train neuroscientists from around the world to understand and perform FMRI research. |
1998 - Present Radiology Clinical Service, Implemented and educated radiologists and MR technologists about diffusion and perfusion MRI, analyzed clinical image data on a per-call basis. |
Graduate Student Education |
1997 - 2012 Course Director, Biophysics 239: "FMRI Contrast Mechanisms and Applications"; Developed an advanced level graduate course for students undertaking MRI research. |
1999 - 2007 Lecturer, "Advanced Neurosystems" Department of Cell Biology and Anatomy, present a lecture discussing the basis of FMRI each time the course is offered. |
2012 - Present Guest Lecturer, Biophysics 239: "FMRI Contrast Mechanisms" graduate course. |
EXTRAMURAL TEACHING: |
Continuing Medical Education |
2001 - 2004 GE Medical Systems, Waukesha, WI, two-part series on the “Introduction to FMRI” as part of a continuing education course for GE employees, which was part of a teaching collaboration with Marquette University |
Graduate Student Education |
1986 Fall, Department of Electrical Engineering and Computer Science, MIT, Teaching assistant for "Introduction to Electronics"; conducted labs, graded problem sets, had office hours, gave quiz reviews |
1989 Fall, Department of Electrical Engineering and Computer Science, MIT, Head teaching assistant for Dr. Bose for "Acoustics"; supervised six other teaching assistants, lectured 4 hours per week, conducted demonstrations, graded problem sets, wrote exams, held office hours |
1990 Spring, Department of Electrical Engineering and Computer Science, MIT, Teaching Assistant for "Circuits and Electronics"; taught group tutorials (four 1 hour lectures per week), wrote and graded problem sets and supervised laboratory sessions |
1992 Spring, Harvard-MIT, Division of Health Science and Technology; Teaching assistant for "Magnetic Resonance"; assisted at lectures, graded problem sets |
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Medical Students |
Fred Dawson, Medical College of Wisconsin, 06/2004 - 08/2004 |
Matthew Fishman, Medical College of Wisconsin, 06/2006 - 08/2006 |
Jessica Stratton, Medical College of Wisconsin, 06/2008 - 08/2008 |
Brandon Bodager, Medical College of Wisconsin, 06/2009 - 08/2009 |
Jose Palomares, Medical College of Wisconsin, 2016 - 2019 |
Ran Pan, Medical College of Wisconsin, 09/2017 - 11/2017 |
Thomas Reith, Medical College of Wisconsin, 2018 - 2020 |
Michael Guo, Medical College of Wisconsin, 2018 - 2020 |
Many more rotating residents and fellows, Medical College of Wisconsin |
Postdoctoral Students |
Kimberly Pechman, Ph.D., Medical College of Wisconsin, 2007 - 2009 (under Drs. Schmainda and Kurpad), Current Position: Research Scientist, Vanderbilt University, Nashville, TN |
Faculty |
Sarah White, M.D., Staff Radiologist, Medical College of Wisconsin, 2013 Scientific Advisor to RSNA Research Scholar |
Theresa Kelly, M.D., Assistant Professor, Medical College of Wisconsin, 2013 Mentor to Clinical Research Scholar (CTSI) Clinical Scholars Award |
Bill Hall, M.D., Assistant Professor, Medical College of Wisconsin, 2018 Mentor to RSNA Research Scholar |
EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Undergraduate Students |
Rebecca Hanson, Department of Biomedical Engineering, Marquette University, 06/2000 - 08/2001 |
Allen Joseph, Department of Biomedical Engineering, Marquette University, 06/2001 - 12/2001 |
Michael Piche, Department of Biomedical Engineering, University of Wisconsin, Madison, 06/2002 - 08/2002 |
Kevin Kvasnica, Department of Nuclear Engineering, University of Wisconsin-Madison, 06/2006 - 09/2006 |
Many more summer undergraduate students |
Medical Students |
Sarah Kohn, MCWW Medical School, 2020 |
Many more rotating residents and fellows |
Graduate Students |
Students Advised |
Aaron Olson, MSE, Department of Biomedical Engineering, Marquette University, 2000, Current (known) Position: Graduate of MCW Medical School |
PhD Students Advised |
Young Ro Kim, Biophysics Research Institute, Medical College of Wisconsin, 05/2001, Current Position: Assistant Professor of Radiology, Center for Molecular Imaging, Harvard Medical School; Assistant in NeuroImaging, Massachusetts General Hospital, Charlestown, MA |
Arvind Pathak, MCW/Marquette University Functional Imaging Program, Medical College of Wisconsin, 12/2001, Current Position: Associate Professor of Radiology & Radiological Science, Johns Hopkins University, Baltimore, MD |
Kevin Bennett, Department of Biophysics, Medical College of Wisconsin, 2003, Current Position: Associate Professor of Radiology, Washington University School of Medicine, Biomedical Magnetic Resonance Laboratory, St. Louis, MO |
Christopher C. Quarles, Department of Biophysics, Medical College of Wisconsin, 2004, Current Position: Professor and Chair, Division of Neuroimaging Research; Director, Barrow Neuroimaging Innovation Center, Phoenix, AZ |
Todd Jensen, MCW/Marquette University Functional Imaging Program, Medical College of Wisconsin, 2006, Current Position: Founder, Jensen Informatics, LLC |
Moses Darpolor, MCW/Marquette University Functional Imaging Program, Medical College of Wisconsin, 2006, Current Position: Associate Professor, Department of Natural Sciences,
Stillman College, Tuscaloosa, AL |
Eric Paulson, Department of Biophysics, Medical College of Wisconsin, 07/2008, Current Position: Associate Professor, Department of Radiation Oncology, MCW
Milwaukee, WI |
Douglas Prah, Department of Biophysics, Medical College of Wisconsin, 08/2008, Current Position: Assistant Professor, Department of Radiation Oncology, MCW
Milwaukee, WI |
Peter LaViolette, Department of Biophysics, Medical College of Wisconsin, 08/2011, Current Position: Assistant Professor, MCW, Department of Radiology |
Alex Cohen, Department of Biophysics, Medical College of Wisconsin, 05/2014 MRI and Diffusion Imaging in Liver Cirrhosis, Current Position Research Scientist, MCW Department of Radiology |
PhD Committees |
Kelly Karau, MCW/Marquette University Functional Imaging Program, Medical College of Wisconsin, 2001 |
Michael Ellingson, MCW/Marquette University Functional Imaging Program, Medical College of Wisconsin, 2004 |
Rachael Kirchoff, MCW/Marquette University Functional Imaging Program, Medical College of Wisconsin, 2006 |
Joan Forder, Department of Physiology, Medical College of Wisconsin, 2006 |
Ritobratta Datta, Department of Biophysics, Medical College of Wisconsin, 2006 |
Christopher Pawela, Department of Biophysics, Medical College of Wisconsin, 2008 |
Ben Ellingson, Marquette University, 2008 |
Andrew Nencka, Department of Biophysics, Medical College of Wisconsin, 2009 |
Andrew Hahn, Department of Biophysics, Medical College of Wisconsin, 2010 |
Jain Mangalathu, MCW/Marquette University Functional Imaging Program, Medical College of Wisconsin, 06/2012 - 08/2012 |
Ben Stangel, Department of Biophysics, Medical College of Wisconsin, 2012 |
MS Students Advised |
Casey Anderson, Department of Biophysics, Medical College of Wisconsin, 05/2016, Current Position: Los Alamos National Laboratory, Los Alamos, NM |
Postdoctoral Students |
Benjamin Ellingson, Ph.D., MCW/Marquette Functional Imaging Program, Medical College of Wisconsin, 2009, Current Position: Assistant Professor, UCLA, Los Angeles, CA |
Residents |
Brandon Laine M.D., Department of Neurosurgery, MCW, 2019 - Present, Current Position: Resident, Medical College of Wisconsin Department of Neurosurgery |
Faculty |
Alex Guimaraes, M.D., Ph.D., Staff Radiologist, Harvard Medical School, Massachusetts General Hospital, 2008 - 2009 Scientific Advisor to RSNA Research Scholar for research entitled: “Evaluation of Magnetic Nanoparticle Enhanced Magnetic Resonance Imaging in Clinical Autoimmune Diabetes” |
COMMUNITY SERVICE ACTIVITIES: |
06/2011 Guest Speaker “A Scientist, Entrepreneur and Mother,” Women in Science Luncheon, Milwaukee, WI |
01/24/2015 Guest Speaker, “The Joy of Insight,” Petawa Professional Women Speaker Series, Petawa Residence and Cultural Center, Milwaukee, WI |
07/31/2015 Guest Speaker “Careers in Science,” Summit Educational Association, Milwaukee, WI |
10/19/2015 Participant, “Leadership for Social Inclusion and Equity” workshop |
02/04/2016 Guest Speaker, “Faith & Science,” Petawa Residence and Cultural Center, Milwaukee, WI |
08/12/2017 Invited Workshop Participant, “The Dialogue Initiative” workshop to improve our communication with youth, Shellbourne Conference Center, Valparaiso, IN |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Sarna SK, Soergel KH, Harig JM, Loo FD, Wood CM, Donahue KM, Ryan RP, Arndorfer RC. Spatial and temporal patterns of human jejunal contractions. Am J Physiol. 1989 Sep;257(3 Pt 1):G423-32. |
2. Rosowski JJ, Davis PJ, Merchant SN, Donahue KM, Coltrera MD. Cadaver middle ears as models for living ears: comparisons of middle ear input immittance. Ann Otol Rhinol Laryngol. 1990 May;99(5 Pt 1):403-12. |
3. Kwong KK, Chesler DA, Weisskoff RM, Donahue KM, Davis TL, Ostergaard L, Campbell TA, Rosen BR. MR perfusion studies with T1-weighted echo planar imaging. Magn Reson Med. 1995 Dec;34(6):878-87. |
4. Kwong KK, Wanke I, Donahue KM, Davis TL, Rosen BR. EPI imaging of global increase of brain MR signal with breath-hold preceded by breathing O2. Magn Reson Med. 1995 Mar;33(3):448-52. |
5. Donahue KM, Weisskoff RM, Parmelee DJ, Callahan RJ, Wilkinson RA, Mandeville JB, Rosen BR. Dynamic Gd-DTPA enhanced MRI measurement of tissue cell volume fraction. Magn Reson Med. 1995 Sep;34(3):423-32. |
6. Donahue KM, Van Kylen J, Guven S, El-Bershawi A, Luh WM, Bandettini PA, Cox RW, Hyde JS, Kissebah AH. Simultaneous gradient-echo/spin-echo EPI of graded ischemia in human skeletal muscle. J Magn Reson Imaging. 1998;8(5):1106-13. |
7. Donahue KM, Burstein D, Manning WJ, Gray ML. Studies of Gd-DTPA relaxivity and proton exchange rates in tissue. Magn Reson Med. 1994 Jul;32(1):66-76. |
8. Donahue KM, Weisskoff RM, Chesler DA, Kwong KK, Bogdanov AA Jr, Mandeville JB, Rosen BR. Improving MR quantification of regional blood volume with intravascular T1 contrast agents: accuracy, precision, and water exchange. Magn Reson Med. 1996 Dec;36(6):858-67. |
9. Donahue KM, Weisskoff RM, Burstein D. Water diffusion and exchange as they influence contrast enhancement. J Magn Reson Imaging. 1997;7(1):102-10. |
10. Donahue KM, Krouwer HG, Rand SD, Pathak AP, Marszalkowski CS, Censky SC, Prost RW. Utility of simultaneously acquired gradient-echo and spin-echo cerebral blood volume and morphology maps in brain tumor patients. Magn Reson Med. 2000 Jun;43(6):845-53. |
11. Allamand V, Donahue KM, Straub V, Davisson RL, Davidson BL, Campbell KP. Early adenovirus-mediated gene transfer effectively prevents muscular dystrophy in alpha-sarcoglycan-deficient mice. Gene Ther. 2000 Aug;7(16):1385-91. |
12. Butzen J, Prost R, Chetty V, Donahue K, Neppl R, Bowen W, Li SJ, Haughton V, Mark L, Kim T, Mueller W, Meyer G, Krouwer H, Rand S. Discrimination between neoplastic and nonneoplastic brain lesions by use of proton MR spectroscopy: the limits of accuracy with a logistic regression model. AJNR Am J Neuroradiol. 2000 Aug;21(7):1213-9. PMCID: PMC8174924 |
13. Kerschner JE, Cruz MJ, Beste DJ, Donahue KM, Kehl KS. Computed tomography vs. magnetic resonance imaging of acute bacterial sinusitis: a rabbit model. Am J Otolaryngol. 2000;21(5):298-305. |
14. Straub V, Donahue KM, Allamand V, Davisson RL, Kim YR, Campbell KP. Contrast agent-enhanced magnetic resonance imaging of skeletal muscle damage in animal models of muscular dystrophy. Magn Reson Med. 2000 Oct;44(4):655-9. |
15. Pathak AP, Schmainda KM, Ward BD, Linderman JR, Rebro KJ, Greene AS. MR-derived cerebral blood volume maps: issues regarding histological validation and assessment of tumor angiogenesis. Magn Reson Med. 2001 Oct;46(4):735-47. |
16. Garcia GH, Donahue KM, Ulmer JL, Harris GJ. Qualitative perfusion imaging of the human optic nerve. Ophthalmic Plast Reconstr Surg. 2002 Mar;18(2):107-13. |
17. Kim YR, Rebro KJ, Schmainda KM. Water exchange and inflow affect the accuracy of T1-GRE blood volume measurements: implications for the evaluation of tumor angiogenesis. Magn Reson Med. 2002 Jun;47(6):1110-20. |
18. Durbeej M, Sawatzki SM, Barresi R, Schmainda KM, Allamand V, Michele DE, Campbell KP. Gene transfer establishes primacy of striated vs. smooth muscle sarcoglycan complex in limb-girdle muscular dystrophy. Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8910-5. PMCID: PMC166412 |
19. Abu-Hajir M, Rand SD, Krouwer HG, Schmainda KM. Noninvasive assessment of neoplastic angiogenesis: the role of magnetic resonance imaging. Semin Thromb Hemost. 2003 Jun;29(3):309-15. |
20. Pathak AP, Rand SD, Schmainda KM. The effect of brain tumor angiogenesis on the in vivo relationship between the gradient-echo relaxation rate change (DeltaR2*) and contrast agent (MION) dose. J Magn Reson Imaging. 2003 Oct;18(4):397-403. |
21. Bennett KM, Schmainda KM, Bennett RT, Rowe DB, Lu H, Hyde JS. Characterization of continuously distributed cortical water diffusion rates with a stretched-exponential model. Magn Reson Med. 2003 Oct;50(4):727-34. |
22. Badruddoja MA, Krouwer HG, Rand SD, Rebro KJ, Pathak AP, Schmainda KM. Antiangiogenic effects of dexamethasone in 9L gliosarcoma assessed by MRI cerebral blood volume maps. Neuro Oncol. 2003 Oct;5(4):235-43. PMCID: PMC1920679 |
23. Ulmer JL, Hacein-Bey L, Mathews VP, Mueller WM, DeYoe EA, Prost RW, Meyer GA, Krouwer HG, Schmainda KM. Lesion-induced pseudo-dominance at functional magnetic resonance imaging: implications for preoperative assessments. Neurosurgery. 2004 Sep;55(3):569-79; discussion 580-1. |
24. Schmainda KM, Rand SD, Joseph AM, Lund R, Ward BD, Pathak AP, Ulmer JL, Badruddoja MA, Krouwer HG. Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis. AJNR Am J Neuroradiol. 2004 Oct;25(9):1524-32. PMCID: PMC7976425 |
25. Bennett KM, Hyde JS, Rand SD, Bennett R, Krouwer HG, Rebro KJ, Schmainda KM. Intravoxel distribution of DWI decay rates reveals C6 glioma invasion in rat brain. Magn Reson Med. 2004 Nov;52(5):994-1004. |
26. Schmainda KM, Rand SD, Joseph AM, Lund R, Ward BD, Pathak AP, Ulmer JL, Badruddoja MA, Krouwer HGJ. Erratum: Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis (American Journal of Neuroradiology (October 2004) 25 (1524-1532)) American Journal of Neuroradiology. 2005;26(3):686. |
27. Quarles CC, Krouwer HG, Rand SD, Schmainda KM. Dexamethasone normalizes brain tumor hemodynamics as indicated by dynamic susceptibility contrast MRI perfusion parameters. Technol Cancer Res Treat. 2005 Jun;4(3):245-9. |
28. Quarles CC, Ward BD, Schmainda KM. Improving the reliability of obtaining tumor hemodynamic parameters in the presence of contrast agent extravasation. Magn Reson Med. 2005 Jun;53(6):1307-16. |
29. Ahunbay E, Schmainda K, Lund R, Prost R, Ulmer J, Alaly J, Deasy J, Schultz C, li X. SU‐FF‐J‐105: Tools for Voxel‐By‐Voxel Correlation of Radiotherapy Dose and MR Signals From Multiple Physiological/functional MRI Modalities Medical Physics. June 2005;32(6):1944. |
30. Boxerman JL, Schmainda KM, Weisskoff RM. Relative cerebral blood volume maps corrected for contrast agent extravasation significantly correlate with glioma tumor grade, whereas uncorrected maps do not. AJNR Am J Neuroradiol. 2006 Apr;27(4):859-67. PMCID: PMC8134002 |
31. Bennett KM, Hyde JS, Schmainda KM. Water diffusion heterogeneity index in the human brain is insensitive to the orientation of applied magnetic field gradients. Magn Reson Med. 2006 Aug;56(2):235-9. |
32. Quarles CC, Schmainda KM. Assessment of the morphological and functional effects of the anti-angiogenic agent SU11657 on 9L gliosarcoma vasculature using dynamic susceptibility contrast MRI. Magn Reson Med. 2007 Apr;57(4):680-7. |
33. Pathak AP, Ward BD, Schmainda KM. A novel technique for modeling susceptibility-based contrast mechanisms for arbitrary microvascular geometries: the finite perturber method. Neuroimage. 2008 Apr 15;40(3):1130-43. PMCID: PMC2408763 |
34. Paulson ES, Schmainda KM. Comparison of dynamic susceptibility-weighted contrast-enhanced MR methods: recommendations for measuring relative cerebral blood volume in brain tumors. Radiology. 2008 Nov;249(2):601-13. PMCID: PMC2657863 |
35. Ellington BM, Schmit BD, Gourab K, Sieber-Blum M, Hu YF, Schmainda KM. Diffusion heterogeneity tensor MRI (?-Dti): mathematics and initial applications in spinal cord regeneration after trauma - biomed 2009. Biomed Sci Instrum. 2009;45:167-72. |
36. Jensen TR, Schmainda KM. Computer-aided detection of brain tumor invasion using multiparametric MRI. J Magn Reson Imaging. 2009 Sep;30(3):481-9. PMCID: PMC4321878 |
37. Hu LS, Baxter LC, Pinnaduwage DS, Paine TL, Karis JP, Feuerstein BG, Schmainda KM, Dueck AC, Debbins J, Smith KA, Nakaji P, Eschbacher JM, Coons SW, Heiserman JE. Optimized preload leakage-correction methods to improve the diagnostic accuracy of dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in posttreatment gliomas. AJNR Am J Neuroradiol. 2010 Jan;31(1):40-8. PMCID: PMC4323177 |
38. Ellingson BM, Rand SD, Malkin MG, Schmainda KM. Utility of functional diffusion maps to monitor a patient diagnosed with gliomatosis cerebri. J Neurooncol. 2010 May;97(3):419-23. PMCID: PMC2956408 |
39. Ellingson BM, Malkin MG, Rand SD, Connelly JM, Quinsey C, LaViolette PS, Bedekar DP, Schmainda KM. Validation of functional diffusion maps (fDMs) as a biomarker for human glioma cellularity. J Magn Reson Imaging. 2010 Mar;31(3):538-48. PMCID: PMC2903058 |
40. Prah DE, Paulson ES, Nencka AS, Schmainda KM. A simple method for rectified noise floor suppression: Phase-corrected real data reconstruction with application to diffusion-weighted imaging. Magn Reson Med. 2010 Aug;64(2):418-29. PMCID: PMC4321728 |
41. Bedekar D, Jensen T, Schmainda KM. Standardization of relative cerebral blood volume (rCBV) image maps for ease of both inter- and intrapatient comparisons. Magn Reson Med. 2010 Sep;64(3):907-13. PMCID: PMC4323176 |
42. Ellingson BM, Malkin MG, Rand SD, LaViolette PS, Connelly JM, Mueller WM, Schmainda KM. Volumetric analysis of functional diffusion maps is a predictive imaging biomarker for cytotoxic and anti-angiogenic treatments in malignant gliomas. J Neurooncol. 2011 Mar;102(1):95-103. PMCID: PMC3033973 |
43. LaViolette PS, Rand SD, Raghavan M, Ellingson BM, Schmainda KM, Mueller W. Three-dimensional visualization of subdural electrodes for presurgical planning. Neurosurgery. 2011 Mar;68(1 Suppl Operative):152-60; discussion 160-1. PMCID: PMC4339031 |
44. Darpolor MM, Molthen RC, Schmainda KM. Multimodality imaging of abnormal vascular perfusion and morphology in preclinical 9L gliosarcoma model. PLoS One. 2011 Jan 31;6(1):e16621. PMCID: PMC3031600 |
45. LaViolette PS, Rand SD, Ellingson BM, Raghavan M, Lew SM, Schmainda KM, Mueller W. 3D visualization of subdural electrode shift as measured at craniotomy reopening. Epilepsy Res. 2011 Mar;94(1-2):102-9. PMCID: PMC4329774 |
46. Ellingson BM, LaViolette PS, Rand SD, Malkin MG, Connelly JM, Mueller WM, Prost RW, Schmainda KM. Spatially quantifying microscopic tumor invasion and proliferation using a voxel-wise solution to a glioma growth model and serial diffusion MRI. Magn Reson Med. 2011 Apr;65(4):1131-43. PMCID: PMC3065939 |
47. Pechman KR, Donohoe DL, Bedekar DP, Kurpad SN, Hoffmann RG, Schmainda KM. Characterization of bevacizumab dose response relationship in U87 brain tumors using magnetic resonance imaging measures of enhancing tumor volume and relative cerebral blood volume. J Neurooncol. 2011 Nov;105(2):233-9. PMCID: PMC4323180 |
48. Ellingson BM, Cloughesy TF, Lai A, Mischel PS, Nghiemphu PL, Lalezari S, Schmainda KM, Pope WB. Graded functional diffusion map-defined characteristics of apparent diffusion coefficients predict overall survival in recurrent glioblastoma treated with bevacizumab. Neuro Oncol. 2011 Oct;13(10):1151-61. PMCID: PMC3177656 |
49. Pechman KR, Donohoe DL, Bedekar DP, Kurpad SN, Schmainda KM. Evaluation of combined bevacizumab plus irinotecan therapy in brain tumors using magnetic resonance imaging measures of relative cerebral blood volume. Magn Reson Med. 2012 Oct;68(4):1266-72. PMCID: PMC3323703 |
50. Boxerman JL, Prah DE, Paulson ES, Machan JT, Bedekar D, Schmainda KM. The Role of preload and leakage correction in gadolinium-based cerebral blood volume estimation determined by comparison with MION as a criterion standard. AJNR Am J Neuroradiol. 2012 Jun;33(6):1081-7. PMCID: PMC4331024 |
51. Schmainda KM. Diffusion-weighted MRI as a biomarker for treatment response in glioma. CNS Oncol. 2012 Nov;1(2):169-80. PMCID: PMC3734866 |
52. Verma S, Landisch R, Quirk B, Schmainda K, Prah M, Whelan HT, Willoughby RE Jr. Presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis. Pediatr Infect Dis J. 2013 Feb;32(2):189-91. PMCID: PMC3548939 |
53. LaViolette PS, Cohen AD, Prah MA, Rand SD, Connelly J, Malkin MG, Mueller WM, Schmainda KM. Vascular change measured with independent component analysis of dynamic susceptibility contrast MRI predicts bevacizumab response in high-grade glioma. Neuro Oncol. 2013 Apr;15(4):442-50. PMCID: PMC3607265 |
54. Cohen AD, LaViolette PS, Prah M, Connelly J, Malkin MG, Rand SD, Mueller WM, Schmainda KM. Effects of perfusion on diffusion changes in human brain tumors. J Magn Reson Imaging. 2013 Oct;38(4):868-75. PMCID: PMC3735792 |
55. Boxerman JL, Paulson ES, Prah MA, Schmainda KM. The effect of pulse sequence parameters and contrast agent dose on percentage signal recovery in DSC-MRI: implications for clinical applications. AJNR Am J Neuroradiol. 2013 Jul;34(7):1364-9. PMCID: PMC4316677 |
56. Liu X, Pillay S, Li R, Vizuete JA, Pechman KR, Schmainda KM, Hudetz AG. Multiphasic modification of intrinsic functional connectivity of the rat brain during increasing levels of propofol. Neuroimage. 2013 Dec;83:581-92. PMCID: PMC3815996 |
57. LaViolette PS, Daun MK, Paulson ES, Schmainda KM. Effect of contrast leakage on the detection of abnormal brain tumor vasculature in high-grade glioma. J Neurooncol. 2014 Feb;116(3):543-549. PMCID: PMC4316680 |
58. Schmainda KM, Prah M, Connelly J, Rand SD, Hoffman RG, Mueller W, Malkin MG. Dynamic-susceptibility contrast agent MRI measures of relative cerebral blood volume predict response to bevacizumab in recurrent high-grade glioma. Neuro Oncol. 2014 Jun;16(6):880-8. PMCID: PMC4022214 |
59. Heroux MS, Chesnik MA, Halligan BD, Al-Gizawiy M, Connelly JM, Mueller WM, Rand SD, Cochran EJ, LaViolette PS, Malkin MG, Schmainda KM, Mirza SP. Comprehensive characterization of glioblastoma tumor tissues for biomarker identification using mass spectrometry-based label-free quantitative proteomics. Physiol Genomics. 2014 Jul 01;46(13):467-81. PMCID: PMC4587597 |
60. LaViolette PS, Mickevicius NJ, Cochran EJ, Rand SD, Connelly J, Bovi JA, Malkin MG, Mueller WM, Schmainda KM. Precise ex vivo histological validation of heightened cellularity and diffusion-restricted necrosis in regions of dark apparent diffusion coefficient in 7 cases of high-grade glioma. Neuro Oncol. 2014 Dec;16(12):1599-606. PMCID: PMC4232087 |
61. Cohen AD, Schieke MC, Hohenwalter MD, Schmainda KM. The effect of low b-values on the intravoxel incoherent motion derived pseudodiffusion parameter in liver. Magn Reson Med. 2015 Jan;73(1):306-11. PMCID: PMC4317387 |
62. Schmainda KM, Zhang Z, Prah M, Snyder BS, Gilbert MR, Sorensen AG, Barboriak DP, Boxerman JL. Dynamic susceptibility contrast MRI measures of relative cerebral blood volume as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 multicenter trial. Neuro Oncol. 2015 Aug;17(8):1148-56. PMCID: PMC4490871 |
63. Jafari-Khouzani K, Emblem KE, Kalpathy-Cramer J, Bjørnerud A, Vangel MG, Gerstner ER, Schmainda KM, Paynabar K, Wu O, Wen PY, Batchelor T, Rosen B, Stufflebeam SM. Repeatability of Cerebral Perfusion Using Dynamic Susceptibility Contrast MRI in Glioblastoma Patients. Transl Oncol. 2015 Jun;8(3):137-46. PMCID: PMC4486737 |
64. Prah MA, Stufflebeam SM, Paulson ES, Kalpathy-Cramer J, Gerstner ER, Batchelor TT, Barboriak DP, Rosen BR, Schmainda KM. Repeatability of Standardized and Normalized Relative CBV in Patients with Newly Diagnosed Glioblastoma. AJNR Am J Neuroradiol. 2015 Sep;36(9):1654-61. PMCID: PMC4567906 |
65. Boxerman JL, Schmainda KM, Zhang Z, Barboriak DP. Dynamic susceptibility contrast MRI measures of relative cerebral blood volume continue to show promise as an early response marker in the setting of bevacizumab treatment. Neuro Oncol. 2015 Nov;17(11):1538-9. PMCID: PMC4648309 |
66. Mickevicius NJ, Carle AB, Bluemel T, Santarriaga S, Schloemer F, Shumate D, Connelly J, Schmainda KM, LaViolette PS. Location of brain tumor intersecting white matter tracts predicts patient prognosis. J Neurooncol. 2015 Nov;125(2):393-400. PMCID: PMC6094943 |
67. Renu D, Aggarwal P, Bhat V, Cherukuri SC, Livi C, Rosenberg M, Tata P, Al-Gizawiy M, Schmainda KM, Mizra SP. Molecular Subtypes in Glioblastoma
Multiforme: Integrated Analysis Using Agilent GeneSpring and Mass Profiler
Professional Multi-Omics Software. Agilent Technologies, Inc. 2015; 5991-5505EN. |
68. Huang W, Chen Y, Fedorov A, Li X, Jajamovich GH, Malyarenko DI, Aryal MP, LaViolette PS, Oborski MJ, O'Sullivan F, Abramson RG, Jafari-Khouzani K, Afzal A, Tudorica A, Moloney B, Gupta SN, Besa C, Kalpathy-Cramer J, Mountz JM, Laymon CM, Muzi M, Schmainda K, Cao Y, Chenevert TL, Taouli B, Yankeelov TE, Fennessy F, Li X. The Impact of Arterial Input Function Determination Variations on Prostate Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge. Tomography. 2016 Mar;2(1):56-66. PMCID: PMC4869732 |
69. Gerstner ER, Zhang Z, Fink JR, Muzi M, Hanna L, Greco E, Prah M, Schmainda KM, Mintz A, Kostakoglu L, Eikman EA, Ellingson BM, Ratai EM, Sorensen AG, Barboriak DP, Mankoff DA, ACRIN 6684 Trial Group. ACRIN 6684: Assessment of Tumor Hypoxia in Newly Diagnosed Glioblastoma Using 18F-FMISO PET and MRI. Clin Cancer Res. 2016 Oct 15;22(20):5079-5086. PMCID: PMC5065740 |
70. Nguyen HS, Milbach N, Hurrell SL, Cochran E, Connelly J, Bovi JA, Schultz CJ, Mueller WM, Rand SD, Schmainda KM, LaViolette PS. Progressing Bevacizumab-Induced Diffusion Restriction Is Associated with Coagulative Necrosis Surrounded by Viable Tumor and Decreased Overall Survival in Patients with Recurrent Glioblastoma. AJNR Am J Neuroradiol. 2016 Dec;37(12):2201-2208. PMCID: PMC5161572 |
71. McGarry SD, Hurrell SL, Kaczmarowski AL, Cochran EJ, Connelly J, Rand SD, Schmainda KM, LaViolette PS. Magnetic Resonance Imaging-Based Radiomic Profiles Predict Patient Prognosis in Newly Diagnosed Glioblastoma Before Therapy. Tomography. 2016 Sep;2(3):223-228. PMCID: PMC5074084 |
72. Paulson ES, Prah DE, Schmainda KM. Spiral Perfusion Imaging With Consecutive Echoes (SPICE™) for the Simultaneous Mapping of DSC- and DCE-MRI Parameters in Brain Tumor Patients: Theory and Initial Feasibility. Tomography. 2016 Dec;2(4):295-307. PMCID: PMC5226659 |
73. Doan NB, Nguyen HS, Montoure A, Al-Gizawiy MM, Mueller WM, Kurpad S, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP. Acid ceramidase is a novel drug target for pediatric brain tumors. Oncotarget. 2017 Apr 11;8(15):24753-24761. PMCID: PMC5421885 |
74. Bell LC, Does MD, Stokes AM, Baxter LC, Schmainda KM, Dueck AC, Quarles CC. Optimization of DSC MRI Echo Times for CBV Measurements Using Error Analysis in a Pilot Study of High-Grade Gliomas. AJNR Am J Neuroradiol. 2017 Sep;38(9):1710-1715. PMCID: PMC5591773 |
75. Doan NB, Nguyen HS, Al-Gizawiy MM, Mueller WM, Sabbadini RA, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP. Acid ceramidase confers radioresistance to glioblastoma cells. Oncol Rep. 2017 Oct;38(4):1932-1940. PMCID: PMC5652937 |
76. Doan NB, Alhajala H, Al-Gizawiy MM, Mueller WM, Rand SD, Connelly JM, Cochran EJ, Chitambar CR, Clark P, Kuo J, Schmainda KM, Mirza SP. Acid ceramidase and its inhibitors: a <i>de novo</i> drug target and a new class of drugs for killing glioblastoma cancer stem cells with high efficiency. Oncotarget. 2017 Dec 22;8(68):112662-112674. PMCID: PMC5762539 |
77. Prah MA, Al-Gizawiy MM, Mueller WM, Cochran EJ, Hoffmann RG, Connelly JM, Schmainda KM. Spatial discrimination of glioblastoma and treatment effect with histologically-validated perfusion and diffusion magnetic resonance imaging metrics. J Neurooncol. 2018 Jan;136(1):13-21. PMCID: PMC5756123 |
78. Newitt DC, Malyarenko D, Chenevert TL, Quarles CC, Bell L, Fedorov A, Fennessy F, Jacobs MA, Solaiyappan M, Hectors S, Taouli B, Muzi M, Kinahan PE, Schmainda KM, Prah MA, Taber EN, Kroenke C, Huang W, Arlinghaus LR, Yankeelov TE, Cao Y, Aryal M, Yen YF, Kalpathy-Cramer J, Shukla-Dave A, Fung M, Liang J, Boss M, Hylton N. Multisite concordance of apparent diffusion coefficient measurements across the NCI Quantitative Imaging Network. J Med Imaging (Bellingham). 2018 Jan;5(1):011003. PMCID: PMC5633866 |
79. Malyarenko D, Fedorov A, Bell L, Prah M, Hectors S, Arlinghaus L, Muzi M, Solaiyappan M, Jacobs M, Fung M, Shukla-Dave A, McManus K, Boss M, Taouli B, Yankeelov TE, Quarles CC, Schmainda K, Chenevert TL, Newitt DC. Toward uniform implementation of parametric map Digital Imaging and Communication in Medicine standard in multisite quantitative diffusion imaging studies. J Med Imaging (Bellingham). 2018 Jan;5(1):011006. PMCID: PMC5658654 |
80. Chitambar CR, Al-Gizawiy MM, Alhajala HS, Pechman KR, Wereley JP, Wujek R, Clark PA, Kuo JS, Antholine WE, Schmainda KM. Gallium Maltolate Disrupts Tumor Iron Metabolism and Retards the Growth of Glioblastoma by Inhibiting Mitochondrial Function and Ribonucleotide Reductase. Mol Cancer Ther. 2018 Jun;17(6):1240-1250. PMCID: PMC5984712 |
81. Schmainda KM, Prah MA, Rand SD, Liu Y, Logan B, Muzi M, Rane SD, Da X, Yen YF, Kalpathy-Cramer J, Chenevert TL, Hoff B, Ross B, Cao Y, Aryal MP, Erickson B, Korfiatis P, Dondlinger T, Bell L, Hu L, Kinahan PE, Quarles CC. Multisite Concordance of DSC-MRI Analysis for Brain Tumors: Results of a National Cancer Institute Quantitative Imaging Network Collaborative Project. AJNR Am J Neuroradiol. 2018 Jun;39(6):1008-1016. PMCID: PMC6002911 |
82. Doan NB, Nguyen HS, Alhajala HS, Jaber B, Al-Gizawiy MM, Ahn EE, Mueller WM, Chitambar CR, Mirza SP, Schmainda KM. Identification of radiation responsive genes and transcriptome profiling via complete RNA sequencing in a stable radioresistant U87 glioblastoma model. Oncotarget. 2018 May 04;9(34):23532-23542. PMCID: PMC5955095 |
83. Alhajala HS, Nguyen HS, Shabani S, Best B, Kaushal M, Al-Gizawiy MM, Erin Ahn EY, Knipstein JA, Mirza S, Schmainda KM, Chitambar CR, Doan NB. Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy <i>via</i> genome-wide transcriptome changes. Oncotarget. 2018 Sep 25;9(75):34122-34131. PMCID: PMC6183347 |
84. Ratai EM, Zhang Z, Fink J, Muzi M, Hanna L, Greco E, Richards T, Kim D, Andronesi OC, Mintz A, Kostakoglu L, Prah M, Ellingson B, Schmainda K, Sorensen G, Barboriak D, Mankoff D, Gerstner ER, ACRIN 6684 trial group. ACRIN 6684: Multicenter, phase II assessment of tumor hypoxia in newly diagnosed glioblastoma using magnetic resonance spectroscopy. PLoS One. 2018;13(6):e0198548. PMCID: PMC6002091 |
85. Bell LC, Semmineh N, An H, Eldeniz C, Wahl R, Schmainda KM, Prah MA, Erickson BJ, Korfiatis P, Wu C, Sorace AG, Yankeelov TE, Rutledge N, Chenevert TL, Malyarenko D, Liu Y, Brenner A, Hu LS, Zhou Y, Boxerman JL, Yen YF, Kalpathy-Cramer J, Beers AL, Muzi M, Madhuranthakam AJ, Pinho M, Johnson B, Quarles CC. Evaluating Multisite rCBV Consistency from DSC-MRI Imaging Protocols and Postprocessing Software Across the NCI Quantitative Imaging Network Sites Using a Digital Reference Object (DRO). Tomography. 2019 Mar;5(1):110-117. PMCID: PMC6403027 |
86. Schmainda KM, Prah MA, Hu LS, Quarles CC, Semmineh N, Rand SD, Connelly JM, Anderies B, Zhou Y, Liu Y, Logan B, Stokes A, Baird G, Boxerman JL. Moving Toward a Consensus DSC-MRI Protocol: Validation of a Low-Flip Angle Single-Dose Option as a Reference Standard for Brain Tumors. AJNR Am J Neuroradiol. 2019 Apr;40(4):626-633. PMCID: PMC6461489 |
87. Schmainda KM, Prah MA, Zhang Z, Snyder BS, Rand SD, Jensen TR, Barboriak DP, Boxerman JL. Quantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor Trial. AJNR Am J Neuroradiol. 2019 Jul;40(7):1132-1139. PMCID: PMC6620020 |
88. Huang W, Chen Y, Fedorov A, Li X, Jajamovich GH, Malyarenko DI, Aryal MP, LaViolette PS, Oborski MJ, O'Sullivan F, Abramson RG, Jafari-Khouzani K, Afzal A, Tudorica A, Moloney B, Gupta SN, Besa C, Kalpathy-Cramer J, Mountz JM, Laymon CM, Muzi M, Kinahan PE, Schmainda K, Cao Y, Chenevert TL, Taouli B, Yankeelov TE, Fennessy F, Li X. The Impact of Arterial Input Function Determination Variations on Prostate Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge, Part II. Tomography. 2019 Mar;5(1):99-109. PMCID: PMC6403046 |
89. Hoxworth JM, Eschbacher JM, Gonzales AC, Singleton KW, Leon GD, Smith KA, Stokes AM, Zhou Y, Mazza GL, Porter AB, Mrugala MM, Zimmerman RS, Bendok BR, Patra DP, Krishna C, Boxerman JL, Baxter LC, Swanson KR, Quarles CC, Schmainda KM, Hu LS. Performance of Standardized Relative CBV for Quantifying Regional Histologic Tumor Burden in Recurrent High-Grade Glioma: Comparison against Normalized Relative CBV Using Image-Localized Stereotactic Biopsies. AJNR Am J Neuroradiol. 2020 Mar;41(3):408-415. PMCID: PMC7077911 |
90. Zhang Q, Cheng G, Pan J, Zielonka J, Xiong D, Myers CR, Feng L, Shin SS, Kim YH, Bui D, Hu M, Bennett B, Schmainda K, Wang Y, Kalyanaraman B, You M. Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I. Cell Commun Signal. 2020 Apr 07;18(1):58. PMCID: PMC7140380 |
91. Bovi JA, Prah MA, Retzlaff AA, Schmainda KM, Connelly JM, Rand SD, Marszalkowski CS, Mueller WM, Siker ML, Schultz CJ. Pulsed Reduced Dose Rate Radiotherapy in Conjunction With Bevacizumab or Bevacizumab Alone in Recurrent High-grade Glioma: Survival Outcomes. Int J Radiat Oncol Biol Phys. 2020 Nov 15;108(4):979-986. PMCID: PMC8655709 |
92. Boxerman JL, Quarles CC, Hu LS, Erickson BJ, Gerstner ER, Smits M, Kaufmann TJ, Barboriak DP, Huang RH, Wick W, Weller M, Galanis E, Kalpathy-Cramer J, Shankar L, Jacobs P, Chung C, van den Bent MJ, Chang S, Al Yung WK, Cloughesy TF, Wen PY, Gilbert MR, Rosen BR, Ellingson BM, Schmainda KM, Jumpstarting Brain Tumor Drug Development Coalition Imaging Standardization Steering Committee. Consensus recommendations for a dynamic susceptibility contrast MRI protocol for use in high-grade gliomas. Neuro Oncol. 2020 Sep 29;22(9):1262-1275. PMCID: PMC7523451 |
93. Alhajala HS, Markley JL, Kim JH, Al-Gizawiy MM, Schmainda KM, Kuo JS, Chitambar CR. The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1. Oncotarget. 2020 Apr 28;11(17):1531-1544. PMCID: PMC7197450 |
94. Bell LC, Semmineh N, An H, Eldeniz C, Wahl R, Schmainda KM, Prah MA, Erickson BJ, Korfiatis P, Wu C, Sorace AG, Yankeelov TE, Rutledge N, Chenevert TL, Malyarenko D, Liu Y, Brenner A, Hu LS, Zhou Y, Boxerman JL, Yen YF, Kalpathy-Cramer J, Beers AL, Muzi M, Madhuranthakam AJ, Pinho M, Johnson B, Quarles CC. Evaluating the Use of rCBV as a Tumor Grade and Treatment Response Classifier Across NCI Quantitative Imaging Network Sites: Part II of the DSC-MRI Digital Reference Object (DRO) Challenge. Tomography. 2020 Jun;6(2):203-208. PMCID: PMC7289259 |
95. Schmainda KM, Prah MA, Marques H, Kim E, Barboriak DP, Boxerman JL. Value of dynamic contrast perfusion MRI to predict early response to bevacizumab in newly diagnosed glioblastoma: results from ACRIN 6686 multicenter trial. Neuro Oncol. 2021 Feb 25;23(2):314-323. PMCID: PMC7906067 |
96. Huang S, Michalek JE, Reardon DA, Wen PY, Floyd JR, Fox PT, Clarke GD, Jerabek PA, Schmainda KM, Muzi M, Hyun H, Lee EQ, Brenner AJ. Assessment of tumor hypoxia and perfusion in recurrent glioblastoma following bevacizumab failure using MRI and <sup>18</sup>F-FMISO PET. Sci Rep. 2021 Apr 07;11(1):7632. PMCID: PMC8027395 |
97. Lee TS, Feeney MB, Schmainda KM, Sherley JL, Prentice DA. Human Fetal Tissue from Elective Abortions in Research and Medicine: Science, Ethics, and the Law. Issues Law Med. 2020;35(1):3-61. |
98. Connelly JM, Prah MA, Santos-Pinheiro F, Mueller W, Cochran E, Schmainda KM. Magnetic Resonance Imaging Mapping of Brain Tumor Burden: Clinical Implications for Neurosurgical Management: Case Report. Neurosurg Open. 2021 Dec;2(4):okab029. PMCID: PMC8508085 |
99. McGarry SD, Brehler M, Bukowy JD, Lowman AK, Bobholz SA, Duenweg SR, Banerjee A, Hurrell SL, Malyarenko D, Chenevert TL, Cao Y, Li Y, You D, Fedorov A, Bell LC, Quarles CC, Prah MA, Schmainda KM, Taouli B, LoCastro E, Mazaheri Y, Shukla-Dave A, Yankeelov TE, Hormuth DA 2nd, Madhuranthakam AJ, Hulsey K, Li K, Huang W, Huang W, Muzi M, Jacobs MA, Solaiyappan M, Hectors S, Antic T, Paner GP, Palangmonthip W, Jacobsohn K, Hohenwalter M, Duvnjak P, Griffin M, See W, Nevalainen MT, Iczkowski KA, LaViolette PS. Multi-Site Concordance of Diffusion-Weighted Imaging Quantification for Assessing Prostate Cancer Aggressiveness. J Magn Reson Imaging. 2022 Jun;55(6):1745-1758. PMCID: PMC9095769 |
100. Reith TP, Prah MA, Choi EJ, Lee J, Wujek R, Al-Gizawiy M, Chitambar CR, Connelly JM, Schmainda KM. Basal Ganglia Iron Content Increases with Glioma Severity Using Quantitative Susceptibility Mapping: A Potential Biomarker of Tumor Severity. Tomography. 2022 Mar 15;8(2):789-797. PMCID: PMC8938779 |
101. Henriksen OM, Del Mar Álvarez-Torres M, Figueiredo P, Hangel G, Keil VC, Nechifor RE, Riemer F, Schmainda KM, Warnert EAH, Wiegers EC, Booth TC. High-Grade Glioma Treatment Response Monitoring Biomarkers: A Position Statement on the Evidence Supporting the Use of Advanced MRI Techniques in the Clinic, and the Latest Bench-to-Bedside Developments. Part 1: Perfusion and Diffusion Techniques. Front Oncol. 2022;12:810263. PMCID: PMC8961422 |
102. Booth TC, Wiegers EC, Warnert EAH, Schmainda KM, Riemer F, Nechifor RE, Keil VC, Hangel G, Figueiredo P, Álvarez-Torres MDM, Henriksen OM. High-Grade Glioma Treatment Response Monitoring Biomarkers: A Position Statement on the Evidence Supporting the Use of Advanced MRI Techniques in the Clinic, and the Latest Bench-to-Bedside Developments. Part 2: Spectroscopy, Chemical Exchange Saturation, Multiparametric Imaging, and Radiomics. Front Oncol. 2021;11:811425. PMCID: PMC8948428 |
103. Amidon RF, Santos-Pinheiro F, Straza M, Prah MA, Mueller WM, Krucoff MO, Connelly JM, Kleefisch CJ, Coss DJ, Cochran EJ, Bovi JA, Schultz CJ, Schmainda KM. Case report: Fractional brain tumor burden magnetic resonance mapping to assess response to pulsed low-dose-rate radiotherapy in newly-diagnosed glioblastoma. Front Oncol. 2022;12:1066191. PMCID: PMC9763264 |
104. Boxerman JL, Snyder BS, Barboriak DP, Schmainda KM. Early post-bevacizumab change in rCBV from DSC-MRI identifies pseudoresponse in recurrent glioblastoma: Results from ACRIN 6677/RTOG 0625. Front Oncol. 2023;13:1061502. PMCID: PMC9909012 |
105. Hangel G, Schmitz-Abecassis B, Sollmann N, Pinto J, Arzanforoosh F, Barkhof F, Booth T, Calvo-Imirizaldu M, Cassia G, Chmelik M, Clement P, Ercan E, Fernández-Seara MA, Furtner J, Fuster-Garcia E, Grech-Sollars M, Guven NT, Hatay GH, Karami G, Keil VC, Kim M, Koekkoek JAF, Kukran S, Mancini L, Nechifor RE, Özcan A, Ozturk-Isik E, Piskin S, Schmainda KM, Svensson SF, Tseng CH, Unnikrishnan S, Vos F, Warnert E, Zhao MY, Jancalek R, Nunes T, Hirschler L, Smits M, Petr J, Emblem KE. Advanced MR Techniques for Preoperative Glioma Characterization: Part 2. J Magn Reson Imaging. 2023 Jun;57(6):1676-1695. PMCID: PMC10947037 |
106. Schmainda KM. Perfusion magnetic resonance imaging for brain tumour characterisation and assessment of treatment response Handbook of Neuro-Oncology Neuroimaging. 1 January 2022:395-414. |
107. Malik DG, Rath TJ, Urcuyo Acevedo JC, Canoll PD, Swanson KR, Boxerman JL, Quarles CC, Schmainda KM, Burns TC, Hu LS. Advanced MRI Protocols to Discriminate Glioma From Treatment Effects: State of the Art and Future Directions. Front Radiol. 2022;2:809373. PMCID: PMC10365126 |
108. Hu LS, D'Angelo F, Weiskittel TM, Caruso FP, Fortin Ensign SP, Blomquist MR, Flick MJ, Wang L, Sereduk CP, Meng-Lin K, De Leon G, Nespodzany A, Urcuyo JC, Gonzales AC, Curtin L, Lewis EM, Singleton KW, Dondlinger T, Anil A, Semmineh NB, Noviello T, Patel RA, Wang P, Wang J, Eschbacher JM, Hawkins-Daarud A, Jackson PR, Grunfeld IS, Elrod C, Mazza GL, McGee SC, Paulson L, Clark-Swanson K, Lassiter-Morris Y, Smith KA, Nakaji P, Bendok BR, Zimmerman RS, Krishna C, Patra DP, Patel NP, Lyons M, Neal M, Donev K, Mrugala MM, Porter AB, Beeman SC, Jensen TR, Schmainda KM, Zhou Y, Baxter LC, Plaisier CL, Li J, Li H, Lasorella A, Quarles CC, Swanson KR, Ceccarelli M, Iavarone A, Tran NL. Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures. Nat Commun. 2023 Sep 28;14(1):6066. PMCID: PMC10539500 |
109. Shiroishi MS, Weinert D, Cen SY, Varghese B, Dondlinger T, Prah M, Mendoza J, Nazemi S, Ameli N, Amini N, Shohas S, Chen S, Bigjahan B, Zada G, Chen T, Neman-Ebrahim J, Chang EL, Chow FE, Fan Z, Yang W, Attenello FJ, Ye J, Kim PE, Patel VN, Lerner A, Acharya J, Hu LS, Quarles CC, Boxerman JL, Wu O, Schmainda KM. A cross-sectional study to test equivalence of low- versus intermediate-flip angle dynamic susceptibility contrast MRI measures of relative cerebral blood volume in patients with high-grade gliomas at 1.5 Tesla field strength Frontiers in Oncology. 2023;13. |
110. Shiroishi MS, Weinert D, Cen SY, Varghese B, Dondlinger T, Prah M, Mendoza J, Nazemi S, Ameli N, Amini N, Shohas S, Chen S, Bigjahan B, Zada G, Chen T, Neman-Ebrahim J, Chang EL, Chow FE, Fan Z, Yang W, Attenello FJ, Ye J, Kim PE, Patel VN, Lerner A, Acharya J, Hu LS, Quarles CC, Boxerman JL, Wu O, Schmainda KM. A cross-sectional study to test equivalence of low- versus intermediate-flip angle dynamic susceptibility contrast MRI measures of relative cerebral blood volume in patients with high-grade gliomas at 1.5 Tesla field strength. Front Oncol. 2023;13:1156843. PMCID: PMC10548232 |
111. Botros NE, Polinger-Hyman D, Beck RT, Kleefisch C, Mrachek EKS, Connelly J, Schmainda KM, Krucoff MO. Magnetic resonance imaging-derived relative cerebral blood volume characteristics in a case of pathologically confirmed neurocysticercosis: illustrative case. J Neurosurg Case Lessons. 2023 Dec 18;6(25). PMCID: PMC10732321 |
112. Al-Gizawiy MM, Wujek RT, Alhajala HS, Cobb JM, Prah MA, Doan NB, Connelly JM, Chitambar CR, Schmainda KM. Potent <i>in vivo</i> efficacy of oral gallium maltolate in treatment-resistant glioblastoma. Front Oncol. 2023;13:1278157. PMCID: PMC10822938 |
113. Prah MA, Schmainda KM. Practical guidance to identify and troubleshoot suboptimal DSC-MRI results. Front Radiol. 2024;4:1307586. PMCID: PMC10913595 |
114. Anil A, Stokes AM, Karis JP, Bell LC, Eschbacher J, Jennings K, Prah MA, Hu LS, Boxerman JL, Schmainda KM, Quarles CC. Identification of a single-dose, low flip angle based CBV threshold for fractional tumor burden (FTB) mapping in recurrent glioblastoma. AJNR Am J Neuroradiol. 2024 May 23. |
Books, Chapters, and Reviews |
1. Birn R, Donahue KM, Bandettini PA. "Magnetic Resonance Imaging: Principles, Pulse Sequences, and Functional Imaging". In: W.R. Hendee (ed), Biomedical Uses of Radiation, Wiley-VDH (1999). |
2. Donahue KM, Ulmer JL. "Neuroimaging: Technology and Clinical Applications". In: Neuroscience Secrets, Hanley and Belfus, Inc. (1999). |
3. Bandettini PA, Birn RM, Donahue KM. "Functional MRI: Background, Methodology, Limits and Implementation." In: J. T. Cacioppo, L. G. Tassinary, G. Bernston (eds.), Handbook of Psychophysiology, Cambridge University Press (2000). |
4. Provenzale JM, Schmainda K. Perfusion Imaging for Brain Tumor Characterization and Assessment of Treatment Response. In: H. Newton and F. Jolesz (eds.), Handbook of Neuro-Oncology Neuroimaging. 2008:264-277. |
5. Schmainda K. Perfusion Imaging for Brain Tumor Characterization and Assessment of Treatment. In: H. Newton and F. Jolesz (eds.), Response Handbook of Neuro-Oncology Neuroimaging (Second Edition). 12 April 2016:335-351. |
Abstracts |
1. Donahue KM, Burstein D. "Tissue relaxivity". 11th Ann. Mtg., SMRM, Berlin, (1992). |
2. Donahue KM, Burstein D. "Proton exchange rates in myocardial tissue with Gd-DTPA administration". 12th Ann. Mtg., SMRM, New York, p.623 (1993). |
3. Donahue KM, Weisskoff RM, Parmelee DJ, Walovitch RC, Mandeville JB, Ouelette HS, Tyeklar Z, Heinig G, Nadler S, Lauffer RB, Rosen BR. "Evaluation of tumor cellular volume fractional and interstitial albumin concentration using Gd-DTPA and a novel albumin-binding contrast agent". 2nd Ann. Mtg., SMR, San Francisco, p. 926, (1994). |
4. Callahan RJ, Wilkinson RA, Bogdanov AA, Jr., Donahue K, Weissleder R, Fischman AJ. "Validation of plasma volume determinations in the rat using an In-111 labeled polymer and I-125 human serum albumin". 42nd Ann. Mtg., Soc. Nuclear Med., Minneapolis, (06/1995). |
5. Kwong KK, Donahue KM, Ostergaard L, Shen T, Bandettini PA, Wanke I, Moore J, Rosen BR. "Mechanism of MR brain signal increase in hyperoxia". 3rd Ann. Mtg., SMR, Nice, p. 768 (08/1995). |
6. Donahue KM, Weisskoff RM, Callahan RC, Wilkinson RA, Parmelee DJ, Binello E, Mandeville JB, Rosen BR. "Dynamic Gd(DTPA)-enhanced MRI measurement of tissue cell fraction: predicted accuracy and correlated with 99mTc(DTPA)-measured cell fraction". 3rd Ann. Mtg., SMR, Nice, p. 169, (08/1995). |
7. Donahue KM, Weisskoff RM, Bogdanov Jr. AA, Mandeville JB, Rosen BR. "Measurement of vascular volume fraction and water permeability with intravascular contrast agents". 3rd Ann. Mtg., SMR, Nice, p. 1073, (08/1995). |
8. Weisskoff RM, Donahue KM, Chesler DA. "Two-site exchange and short TR gradient echo imaging". 4th Ann. Mtg., SMR, New York, (04/1996). |
9. Donahue KM, Weisskoff RM, Chesler DA, Kwong KK, Bogdanov AA, Jr., Mandeville JB, and Rosen BR. "Improving MR quantification of regional blood volume with intravascular T1 contrast agents: accuracy, precision, and water exchange". 4th Ann. Mtg., SMR, New York, (04/1996). |
10. Prost R, Donahue K, Mark L, Li S. "Decrease in water resonance linewidth in glial tumors detected by 0.5T MRS". 5th Ann. Mtg., ISMRM, Vancouver, (04/1997) |
11. Van Kylen J, Donahue KM, Luh W-M, El-Bershawi A, Guven S, Jones K, Kissebah A. "Simultaneous acquisition of flow and BOLD signal in human skeletal muscle during reactive hyperemia". 5th Ann. Mtg., ISMRM, Vancouver, (04/1997). |
12. *Van Kylen J, Donahue KM, Luh W-M, El-Bershawi A, Guven S, Jones K, Kissebah A. "Alternating TE interleaved gradient-echo/spin-echo EPI of graded ischemia in human skeletal muscle". 5th Ann. Mtg., ISMRM, Vancouver, (04/1997). |
13. Donahue KM, *Van Kylen J, Luh W-M, El-Bershawi A, Guven S, Jones K, Kissebah A. "Functional MRI evaluation of insulin action in human skeletal muscle". 5th Ann. Mtg., ISMRM, Vancouver, (04/1997). |
14. Bandettini PA, Donahue KM, Luh W-M, Risinger RC, Stein EA, Li SJ. "A comparison of blood agent level dependence (BALD) and blood oxygenation level dependent (BOLD) R2* and R2 magnitudes and ratios using synchronous gradient-echo and spin-echo (SGS) EPI". 6th Ann. Mtg., ISMRM, Sydney, (04/1998). |
15. Bandettini PA and Donahue KM. "Analysis of activation-induced and post-activation undershoot ∆R2* and ∆R2 magnitudes and ratios at 1.5 Tesla using synchronous gradient-echo and spin-echo (SGS)-EPI". Ann. Mtg., 6th Ann. Mtg., ISMRM, Sydney, (04/1998). |
16. *Pathak AP, Bandettini PA, Risinger R, Stein EA, Donahue KM. "The effect of sequential contrast agent studies on the assessment of relative cerebral blood volume". Ann. Mtg., ISMRM, Sydney, (04/1998). |
17. Kim YR, Donahue KM, "Experimental evaluation of T1 exchange minimization methods for the quantification of compartment volume fractions". 6th Ann. Mtg., ISMRM, Sydney, (04/1998). |
18. Donahue KM, Rand SD, *Pathak AP, Prost RW, Bandettini PA, Krouwer HGJ. "Evaluation of human brain tumor angiogenesis using simultaneously-acquired gradient-echo & spin-echo EPI during dynamic susceptibility contrast". 6th Ann. Mtg., ISMRM, Sydney, (04/1998). |
19. Krouwer HGJ, Donahue KM, *Pathak AP, Rand SD. "Simultaneous Acquisition of blood volume and permeability maps to evaluate brain tumor angiogenesis". ASNR, San Diego, (05/1999). |
20. Luh W-M, Donahue KM, Hyde JS. "Estimation of T1 relaxation times and fractional volumes of brain tissues using EPI-based T1 maps". 7th Ann. Mtg., ISMRM, Philadelphia, p. 610, (05/1999). |
21. Stein EA, Maestas M, Donahue KM, Ross TJ, Hyde JS, Greene AS. "Event-related fMRI in rat whisker barrel cortex at 3 Tesla". 7th Ann. Mtg., ISMRM, Philadelphia, p. 813, (05/1999). |
22. Latour L, Donahue KM, Prost R, Ulmer J. "FLAIR-prepared DWI to reduce the effect of partial volume averaging on ADC maps of cerebral ischemia in humans". 7th Ann. Mtg., ISMRM, Philadelphia, p. 1776, (05/1999). |
23. *Pathak AP, Donahue KM, Risinger R, Hoffman R, Stein E. "The utility of the sequential contrast agent protocol in assessing changes in relative cerebral blood volume". 7th Ann. Mtg., ISMRM, Philadelphia, p. 1873, (05/1999). |
24. Ross TJ, Donahue KM, Hudetz AG, Stein EA. "Regional changes in cerebral blood flow and volume following acute cocaine administration". 7th Ann. Mtg., ISMRM, Philadelphia, p. 813, (05/1999). |
25. Kim YR, Cox R, Donahue KM. "Quantification of fractional blood volume under effects of inflow and water exchange". 7th Ann. Mtg., ISMRM, Philadelphia, p. 1338, (05/1999). |
26. Donahue KM, *Pathak AP, Rand S, Prost R, Krouwer H. "Utility of acquiring vascular blood volume, permeability and morphology information from dynamic susceptibility contrast agent studies in patients with brain tumors". 7th Ann. Mtg., ISMRM, Philadelphia, p. 149, (05/1999). |
27. Ulmer JL, *Olson AT, Latour LL, Nordling OB, Donahue KM. ASNR, Atlanta, April 1999. |
28. *Kim YR, Donahue KM. "Accurate measurement of absolute fractional blood volume for the evaluation of tumor angiogenesis". 8th Ann. Mtg., ISMRM, Denver, p. 1061 (04/2000). |
29. Biswal BB, Pathak AP*, Ward BD, Ulmer JL, Donahue KM, Hudetz AG. "Decoupling of the hemodynamic delay from the task-induced delay in FMRI". 8th Ann. Mtg., ISMRM, Denver, p.990, (04/2000). |
30. Stein EA, Maestas MM, Hudetz A, Donahue K, Ozel B, Greene AS. Effect of hematocrit on BOLD signal changes. 8th Ann. Mtg., ISMRM, Denver, p.926 (04/2000). |
31. *Olson AT, Donahue KM, Latour LL, Ulmer J. "Diffusion weighted imaging (DWI) of early stroke: a comparison of fluid-attenuated inversion-recovery (FLAIR) and non-FLAIR techniques". 8th Ann. Mtg., ISMRM, Denver, p.758, (04/2000). |
32. *Pathak AP, Linderman RJ, Xu H, Ward BD, Greene AS, Donahue KM. "Characterization of ∆R2*/∆R2 for the evaluation of angiogenesis induced changes in vascular morphology". 8th Ann. Mtg., ISMRM, Denver, p.617 (04/2000). |
33. *Pathak AP, Schmainda KM, Ward BD, *Rebro KJ, Greene AS. "MR-derived cerebral blood volume maps: isues regarding histological validation and assessment of tumor angiogenesis." 9th Ann. Mtg., ISMRM, Glasgow, (04/2001). |
34. *Pathak AP, Schmainda KM, Ward BD, *Rebro KJ, Rand SD. "Assessing tumor angiogenesis with dynamic susceptibility contrast fMRI: which morphologic correlates are relevant?" 9th Ann. Mtg., ISMRM, Glasgow, (04/2001). |
35. *Bennett KM, Cox RW, Lu H, Schmainda K, Bennett R, Hyde JS. "ADC measurements in a rat model with compartmental geometric considerations at 3T". 9th Ann. Mtg., ISMRM, Glasgow, (04/2001). |
36. Schmainda KM, *Pathak AP, Badruddoja M, Rand SD, *K. Rebro, Krouwer HGJ. "Effect of dexamethasone treatment on dynamic susceptibility CBV measurements in a rat brain tumor model." 9th Ann. Mtg., ISMRM, Glasgow, (04/2001). |
37. Schmainda KM, Greene AS, Hudetz AG, Ross TJ, Stein EA. "Contribution of resting and activation-induced cerebral blood volume changes to BOLD signal changes in the rat whisker barrel model." 9th Ann. Mtg., ISMRM, Glasgow, (04/2001). |
38. Ulmer JL, Strottman JM, Prost RW, Schmainda KM, Biswal BB, Mark LP, Daniels DL. "Physiologic magnetic resonance imaging of the brain: a conceptual approach to contrast mechanisms and measurable physiologic parameters." 101st Annual Scientific Meeting of American Roentgen Ray Society, Seattle, Washington (04/2001). Awarded the Scientific Exhibit Gold Medal. |
39. Ellingson BM, Schmit BD, Gourab K, Sieber-Blum M, Hu YF, Schmainda KM. Diffusion heterogeneity tensor MRI (α-DTI): Mathematics and initial applications in spinal cord regeneration after trauma 46th Annual Rocky Mountain Bioengineering Symposium and 46th International ISA Biomedical Sciences Instrumentation Symposium 2009. 2009;476:167-172. |
40. Badruddoja MA, Krouwer HG, Schmainda KM, Rand SD, *Rebro KJ, *Pathak AP, Marszalkowski CS. "Dexamethasone decreases relative cerebral blood volume (rCBV) and vessel diameter in 9L gliosarcoma." Society of NeuroOncology, Washington D.C., (11/2001). |
41. Schmainda KM, Rand SD, Badruddoja M, *Pathak AP, *Rebro KJ, Krouwer HG. Dexamethasone Selectively Treats Tumor Vasculature as Demonstrated by Simultaneous GE and SE rCBV Measurements. 10th Annual Meeting of International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii, p 2136 (5/2002). |
42. Ulmer JL, Prost RW, Schmainda KM, Strottman JM, Hacein-Bey L, Mark LP, Daniels DL, Mueller WM, Krouwer HGJ. Physiologic Magnetic Resonance Imaging of Brain Tumors: A conceptual approach to contrast mechanisms and measurable physiologic parameters. Proceedings of 40th Annual Meeting American Society of Neuroradiology, Vancouver, Canada, (05/2002) Awarded Magna Cum Laude. |
43. Rand SD, Schmainda KM *Pathak AP, Badruddoja MA, *Rebro KJ, Krouwer HGJ. Effects of Dexamethasone on Rat 9L Gliosarcoma Model Vasculature Measured with MR Derived Relative Cerebral Blood Volume Maps and Validated with Histologic Analysis. Proceedings of 40th Annual Meeting American Society of Neuroradiology, Vancouver, Canada, (05/2002). |
44. Schmainda KM, Rand SD, *Joseph AM, *Hanson R, Ward BD, *Pathak AP, Baddrudoja MA, Krouwer HGJ. Dynamic Gradient-Echo and Spin-Echo Measurements of Tumor Blood Volume and Vascular Morphology Predict Tumor Grade in Patients with Brain Tumors. International Society for Magnetic Resonance in Medicine. Workshop on In Vivo Functional and Molecular Assessment of Cancer. Santa, Cruz, CA p 122 (10/2002). |
45. Ulmer JL, Prost RW, Schmainda KM, Strottmann JM, Hacein-Bey L, Mark LP. Physiologic MR imaging of Brain Tumors: A Conceptual Approach to Contrast Mechanisms and Measureable Physiologic Parameters. 88th Scientific Assembly and Annual Meeting of the Radiological Society of North America, Chicago, Illinois, (12/2002). |
46. Schmainda KM, Rand SD, *Joseph A, Ward B, *Hanson R, *Pathak AP, Badruddoja M, Krouwer HGJ. A combined gradient-echo/spin-echo DSC method: a surrogate marker for brain tumor histologic grade and angiogenesis in patients. 11th Annual Meeting of International Society for Magnetic Resonance in Medicine, Toronto, Ontario, Canada, (07/2003). |
47. *Bennett KM, Hyde JS, *Rebro KJ, Rand SD, Rowe D, Schmainda KM. Detection of brain tumor invasion. 11th Annual Meeting of International Society for Magnetic Resonance in Medicine, Toronto, Ontario, Canada, (07/2003). |
48. *Quarles CC, Schmainda KM. The importance of contrast agent leakage correction on tumor CBF measurements using DSC MRI. 11th Annual Meeting of International Society for Magnetic Resonance in Medicine, Toronto, Ontario, Canada, (07/2003). |
49. *Bennett KM, Schmainda KM, Rowe D, *Rebro KJ, Hyde JS. A stretched-exponential model of distributed diffusion rates in brain. 11th Annual Meeting of International Society for Magnetic Resonance in Medicine, Toronto, Ontario, Canada, (07/2003). |
50. Krouwer HGJ, Schmainda KM, Rand SD, Badruddoja MA, *Joseph AM, *Hanson R, Ward BD, *Pathak AP. "Dynamic gradient-echo and spin-echo measurements of tumor blood volume and vascular morphology predict grade in patients with brain tumors" 8th Annual Meeting for the Society of Neuro-Oncology, Keystone, Colorado (11/2003). |
51. Krouwer HGJ, Salvan CV, Aralasmak A, Rand SD, Schmainda KM, Prost RW, Ulmer JL, Mueller WM, Meyer GA, Deyoe EA. "Integrated physiologic MR imaging of respectable brain tumors." 8th Annual Meeting for the Society of Neuro-Oncology, Keystone, Colorado (11/2003). |
52. *Wagner ML, Ulmer JL, Rand SD, Krouwer HGJ, Schmainda KM. "The relationship between contrast enhancement and brain tumor neovascularity revealed by blood volume functional imaging." 42nd Annual Meeting of American Society of Neuroradiology, Seattle, WA (05/2004). |
53. *Quarles CC, Ward BD, Schmainda KM. "Improving the reliability of tumor CBF measurements obtained in the presence of contrast extravasation." International Society for Magnetic Resonance in Medicine Workshop on Quantitative Cerebral Perfusion Imaing Using MRI: A Technical Perspective, Venice, Italy, p. 14 (03/2004). |
54. Schmainda KM, Rand SD, Ward BD, Ulmer JL, Krouwer HGJ. "Evaluation of brain tumor neovascularity using a gradient-echo/spin-echo DSC method: biophysical issues and implications for tumor biology in patients." International Society for Magnetic Resonance in Medicine Workshop on Quantitative Cerebral Perfusion Imaging Using MRI: A Technical Perspective, Venice, Italy, p. 127 (03/2004). |
Patents |
1. US Patent No. 6-807-441-B2 (issued October 19, 2007), “Evaluation of Tumor Angiogenesis Using Magnetic Resonance Imaging” Inventor: Kathleen M. Schmainda |
2. US Patent No. US-2009-7,567,832-B2 (issued July 28, 2009), “MRI method for measuring tumor hemodynamic parameters in the presence of contrast agent extravasation” Inventors: Kathleen M. Schmainda, Christopher Quarles, B. Douglas Ward |
3. US Patent No. US-2009-0214437-A1 (issued August 27, 2009), “In Vivo Mitochondrial Labeling Using Positively-Charges Nitroxide Enhanced and Gadolinium Chelate Magnetic Resonance Imaging” Inventors: Balaraman Kalyanaraman, Kathleen M. Schmainda, Joy Joseph, Marcos Lopez, Douglas E. Prah, Micael Hardy |
4. US Patent No. US Utility Patent, 12/601,241 (issued October 2, 2013), “Multiparameter Perfusion Imaging with Leakage Correction” Inventors: Kathleen M. Schmainda, Eric S. Paulson, Douglas E. Prah |
