CURRICULUM VITAE
Laura Smy PhD
Laura Smy PhD
Associate Professor
Department of Pathology
Division of Administration
Department of Pathology
Division of Administration
OFFICE ADDRESS: |
Froedtert/MCW Laboratory Building |
9200 W Wisconsin Ave |
Milwaukee, WI 53226 |
EDUCATION: |
- 1997 Advanced Diploma in Medical Laboratory Technology, The Michener Institute of Education at UHN, Toronto, ON, Canada |
- 2005 Certificate - Pathologist Assistant, Vancouver Community College, Vancouver, BC, Canada |
- 2016 Doctorate of Philosophy - Pharmaceutical Sciences and Biomedical Toxicology, University of Toronto, Toronto, ON, Canada |
- 2011 Honours Bachelor of Science - Chemistry and Biochemistry, University of Toronto, Toronto, ON, Canada |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
2017 - 2019 Clinical Chemistry Fellow, Pathology, University of Utah/ARUP Laboratories, Salt Lake City, UT |
FACULTY APPOINTMENTS: |
07/2019 - 06/2024 Assistant Professor, Pathology and Laboratory Medicine, Medical College of Wisconsin, Milwaukee, WI |
06/2023 - Present MCWFusion PBD Facilitator, Medicine, Medical College of Wisconsin, WI |
07/2024 - Present Associate Professor, Pathology and Laboratory Medicine, Medical College of Wisconsin, Milwaukee, WI |
HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS: |
07/2019 - 08/2022 Section Director of Point-of-Care, Froedtert Hospital, Milwaukee, WI |
07/2019 - Present Co-Director of Chemistry/Toxicology, Wisconsin Diagnostic Laboratories, Milwaukee, WI |
07/2020 - 04/2022 Associate Laboratory Director, Pewaukee and New Berlin Community Hospitals, Milwaukee, WI |
04/2022 - Present CLIA Laboratory Director, Froedtert Community Hospitals - New Berlin, Pewaukee, Oak Creek, Mequon, Greater Milwaukee Area, WI |
HOSPITAL STAFF PRIVILEGES: |
03/2020 - Present Clinical Chemist - on-call coverage, Children's Wisconsin Hospital, Milwaukee, WI |
01/2022 - Present CLIA Laboratory Director, Froedtert Community Hospitals - Pewaukee, New Berlin, Oak Creek, and Mequon, Greater Milwaukee Area, WI |
SPECIALTY BOARDS AND CERTIFICATION: |
Board Certified | Issue Date | Expiration |
Clinical Chemistry | 02/2019 | None |
Licensure | Number | Issue Date | Expiration |
Medical Laboratory Technologist from the College of Medical Laboratory Technologists of Ontario | 10094 | 1997 | None |
AWARDS AND HONORS: |
2012 - 2013 Cohen Benjamin Bursary Fund, University of Toronto |
2013 - 2014 Open Fellowship, University of Toronto |
2014 School of Graduate Studies Conference Grant, University of Toronto, |
2014 Scace Graduate Fellowship,, University of Toronto |
2015 Abstract of Distinction, National Academy of Clinical Biochemistry |
2015 Student Poster Contest Honorable Mention, AACC |
2015 Young Investigator Grant, MSACL |
2015 Ontario Graduate Scholarship, University of Toronto |
2015 SickKids Trainee Travel Grant, The Hospital for Sick Children, |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
1996 - Present Canadian Society for Medical Laboratory Sciences (CSMLS) (Member) |
2012 - 2015 Canadian Society of Pharmacology and Therapeutics (CSPT) (Member) |
2013 - 2019 American Society for Clinical Pharmacology and Therapeutics (ASCPT) (Member) |
2013 - 2017 American Association for the Advancement of Science (AAAS) (Member) |
2015 - Present Canadian Society of Clinical Chemists (CSCC) (Member) |
2015 - Present Association for Diagnostics & Laboratory Medicine (formerly AACC) (Member) |
2016 - 2017 Endocrine Society (Member) |
2017 - 2019 Academy of Clinical Laboratory Physicians and Scientists (ACLPS) (Member) |
2021 - 2023 TIAFT - The International Association of Forensic Toxicologists (Member) |
2022 - Present Academy of Clinical Laboratory Physicians and Scientists (ACLPS) (Member) |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorial Board |
07/2019 AACC CLN Daily News |
Ad-Hoc Reviewer |
2024 - Present Journal of Mass Spectrometry and Advances in the Clinical Lab |
Psychiatry Research |
Journal of Population Therapeutics and Clinical Pharmacology |
AJCP |
Health Science Reports |
Clinical Biochemistry |
Therapeutic Drug Monitoring |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2015 - 2017 Member, Alumni Association, The Michener Institute for Education at UHN |
01/2020 - 01/2022 Member, nominating committee, Chicago Local Section, American Association for Clinical Chemistry |
02/2021 - 02/2022 Member, nominating committee, Steering Committee, Midwest Toxicology Collaborative |
03/2022 - Present Treasurer, Steering Committee, Midwest Toxicology Collaborative |
01/2023 - 09/2023 Chair-elect, Chicago Local Section, American Association for Clinical Chemistry (AACC) |
09/2023 - Present Chair, Chicago Local Section, American Association for Clinical Chemistry (AACC) |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2018 - 2019 Fellow Member, Pediatric and Maternal-Fetal Division Board, American Association for Clinical Chemistry |
2020 - 2022 Member-at-Large, Pediatric and Maternal Fetal Division, American Association for Clinical Chemistry |
09/2021 - Present Member, Education Committee, Academy of Clinical Laboratory Physicians and Scientists (ACLPS) |
07/2022 - Present Secretary, Pediatric and Maternal Fetal Division, American Association for Clinical Chemistry |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
International |
Smy L, Carleton B, Koren G, The safety of inhaled corticosteroid use in pregnancy and childhood [Poster], The 2nd International OTIS-ENTIS Conference, Toronto, ON, 09/19/2014 - 09/21/2014 |
Chaudhry SA, Smy L, Shere M, Koren G, Systematic review of the fetal safety of adalimumab [Poster], The 2nd International OTIS-ENTIS Conference, Toronto, ON, 09/19/2014 - 09/21/2014 |
Smy L, Shaw K, Amstutz U et al, Assessment of Hair Cortisol as a Potential Biomarker for Possible Adrenal Suppression Due to Inhaled Corticosteroid Use in Children with Asthma: A Retrospective Observational Study [Featured Poster], ENDO 2017, Orlando, FL, 05/01/2017 - 05/04/2017 |
Smy, L, The Journey to Incorporating Six Sigma Metrics in the Clinical Laboratory [Oral presentation], Canadian Society of Clinical Chemists Education Roundtable, Webinar, 10/07/2021 |
L Smy, T Yuzyuk, J Genzen, Comparison of Nuclear Magnetic Resonance to Conventional or Liquid Chromatography-Tandem Mass Spectrometry Methods for Lipids, Amino Acids, and Glucose [Poster], 2023 CSCC-CCMG Joint Annual Scientific Meeting, Winnipeg, MB, 06/18/2023 - 06/21/2023 |
National |
Smy L, Koren G, Safety of inhaled corticosteroid use during pregnancy [Poster], The 10th Laurence E. Becker Symposium, Pharmacogenomics: Optimizing Patient Care Through Genome, Toronto, ON, 06/06/2012 |
Smy L, Koren G, Safety of inhaled corticosteroid use during pregnancy [Poster], The joint conference Modern Therapeutics 2012: Advances in Physiology, Pharmacology and Pharmaceutical Sciences Canadian Society of Pharmacologists and Toxicologists, Toronto, ON, 06/12/2012 - 06/15/2012 |
Smy L, Leadley M, Aleksa K, Koren G, Development of a rapid LC-MS/MS method for hair cortisol determination to assess the HPA axis [Poster], The Association for Mass Spectrometry: Applications to the Clinical Lab (MSACL) 2015 US Conference, San Diego, CA, 03/28/2015 - 04/01/2015 |
Smy L, Shaw K, Smith, A et al, Hair cortisol as a novel biomarker of HPA suppression by inhaled corticosteroids in children [Poster], The 13th Laurence E. Becker Symposium, Children are Not Small Adults: Metabolic and Endocrine Disorders of Childhood and Adolescence, Toronto, ON, 06/03/2015 |
Smy L, Shaw K, Smith A et al, Hair cortisol as a novel biomarker of HPA suppression by inhaled corticosteroids in children [Poster], The Canadian Society of Pharmacology and Therapeutics annual meeting, Toronto, ON, 06/07/2015 - 06/10/2015 |
Smy L, Shaw K, Carleton B, Koren G, Hair cortisol as a biomarker of the HPA axis in pregnant women with asthma [Poster], The Canadian Society of Pharmacology and Therapeutics annual meeting, Toronto, ON, 06/07/2015 - 06/10/2015 |
Smy L, Shaw K, Smith A et al, Hair cortisol as a novel biomarker of HPA suppression by inhaled corticosteroids in children [Poster], The Canadian Laboratory Medical Congress, Montreal, QC, 06/20/2015 - 06/24/2015 |
Smy L, Leadley M, Aleksa K, Koren G, Development of a rapid LC-MS/MS
method for hair cortisol determination to assess the HPA axis [Poster], The Canadian Laboratory Medical Congress: Joint Congress of the Canadian Association of Pathologists and Canadian Society of Clinical Chemists, Montreal, QC, 06/20/2015 - 06/24/2015 |
Smy L, Shaw K, Carleton B, Koren G, Hair cortisol as a biomarker of the HPA axis in pregnant women with asthma [Oral presentation, Distinguished abstract award, Honorable mention student poster contest], The American Association for Clinical Chemistry Annual Meeting, Atlanta, GA, 07/26/2015 - 07/30/2015 |
Smy L, Law R, Sadler A et al, Evaluation of imatinib concentrations in samples
submitted for BCR-ABL1 testing [Oral presentation], ACLPS Annual Meeting, Houston, TX, 05/31/2018 - 06/02/2018 |
Smy L, McMillin G, Urine buprenorphine and metabolite patterns in a large cohort of patients [Poster], The American Association for Clinical Chemistry Annual Meeting, Chicago, IL, 07/29/2018 - 08/02/2018 |
Smy L, Kushnir M, Frank E, High Sensitivity LC-MS/MS Method for
Measurement of 3-Methoxytyramine and Observations in Samples Positive for Metanephrines and Dopamine [Poster], The Association for Mass Spectrometry: Applications to the Clinical Lab (MSACL) 2019 US Conference, Palm Springs, CA, 03/31/2019 - 04/04/2019 |
Smy, L, Lee M, De Biase I, Genzen J, Yuzyuk T., Nuclear Magnetic Resonance
(NMR)-Based Serum Metabolic Profiles: Impact of Fasting Status [Oral presentation], ACLPS Annual Meeting, Salt Lake City, UT, 05/30/2019 - 06/01/2019 |
Smy L, Incorporating Six Sigma into your lab quality management system- have you incorporated it yet? [Oral presentation], American Association for Clinical Chemistry Roundtable Sessions (2), Anaheim, CA, 08/04/2019 - 08/06/2019 |
Smy, L, Six Sigma in the Lab [Oral presentation], American Association for Clinical Chemistry Roundtable Sessions (2), Atlanta, GA, 09/25/2021 - 09/30/2021 |
Smy, L, Ho, A, Greer, R, Seiter, J, McMillin, G, Determining the Best Course of Action to Manage Interference in Drug Testing by Immunoassay [Poster], American Association for Clinical Chemistry Annual Meeting, Atlanta, GA, 09/25/2021 - 09/30/2021 |
Local |
Smy L, Carleton B, Koren G, Hair cortisol as a biomarker of the safety of inhaled corticosteroid use during pregnancy and childhood [Poster], The Leslie Dan Faculty of Pharmacy Graduate Research in Progress Symposium, Toronto, ON, 06/16/2013 |
Smy L, Shaw K, Smith A et al, Hair cortisol as a novel biomarker of HPA suppression by inhaled corticosteroids in children [Poster], The Leslie Dan Faculty of Pharmacy Graduate Research in Progress Symposium, Toronto, ON, 06/17/2015 |
Smy L, Law R, Sadler A et al, Evaluation of imatinib concentrations in samples submitted for BCR-ABL1 testing [Oral presentation], Department of Pathology Grand Rounds, Salt Lake City, UT, 05/04/2018 |
Smy, L, Lee M, De Biase I, Genzen J, Yuzyuk T, Nuclear Magnetic Resonance
(NMR)-Based Serum Metabolic Profiles: Impact of Fasting Status [Oral presentation], Department of Pathology Grand Rounds, Salt Lake City, UT, 05/17/2019 |
Laura Smy, Beyond the Jolt: Contemplating the toxicity of energy drinks, Toxicology Grand Rounds, Medical College of Wisconsin, 03/22/2024 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
2019 - 2021 Member, Spurious Results Contamination Task Force, Medical College of Wisconsin and Wisconsin Diagnostic Laboratories |
10/2021 - Present Member, Program Evaluation Committee Pathology Residency Training Program, Pathology and Laboratory Medicine, Medical College of Wisconsin |
11/2022 - Present Member, Quality Committee, Pathology and Laboratory Medicine, Medical College of Wisconsin |
10/2023 - Present Member, Medical Executive Committee, Froedtert Community Hospitals |
Hospital |
07/2019 - Present Member as of 09/2022, Chair 2019-2022, Point-of-Care Management Committee, Froedtert Hospital and the Medical College of Wisconsin |
2019 - Present Member as of 2022, Chair 2019-2022, Point-of-Care Working Group for Collaboration, Froedtert Health and Wisconsin Diagnostic Laboratories |
2019 - 2022 Co-Chair, Point of Service Testing Committee, Froedtert Hospital |
10/2021 - 04/2024 Member, Provider Informaticists Committee, Froedtert Hospital |
07/2022 - Present Co-chair, Core Lab Quality Subcommittee, Wisconsin Diagnostic Laboratories |
09/2022 - Present Member-at-Large, Beaker Steering Committee, Froedtert Health Enterprise |
MCW TEACHING ACTIVITIES: |
Medical Student Education |
2019 - Present Medical student education for Department of Pathology elective courses |
Resident and Fellow Education |
2019 - Present Teaching four or more pathology residents per year for pathology boot camp and during their chemistry and toxicology rotation |
EXTRAMURAL TEACHING: |
Medical Student Education |
2013 - 2016 The Michener Institute for Education at UHN, Instructed and supervised approximately 145 first- and second-year medical laboratory technologist students in their Haematology and Hemostasis and Clinical Chemistry courses inclusive of theory, laboratory exercises, and clinical simulation |
Graduate Student Education |
2018 - 2019 University of Utah, Taught quality management, assurance, and control concepts to a graduate level class |
Resident and Fellow Education |
2002 - 2010 The Hospital for Sick Children, Guided, directed, and assessed the training of over 50 residents, fellows, MLT students, and new employees to meet rotational requirements or attain competency in haematology laboratory tests |
EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Residents |
09/2023 - 06/2024 Katie Golab, Academic and career, Private arrangement during Dr. Golab's Doctor of Clinical Laboratory Science training |
COMMUNITY SERVICE ACTIVITIES: |
2010 Volunteer, Department of Cell and Systems Biology
University of Toronto, Toronto, ON |
2010 - 2017 Volunteer, New College Alumni Association
University of Toronto, Toronto, ON |
2012 - 2014 Pharmaceutical Sciences Graduate Student Association Executive
Graduate Student Union Representative
Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON |
SCIENTIFIC MEETING ABSTRACT REVIEWER / POSTER JUDGE: |
07/2022 - Present Student poster judge - Association for Diagnostics & Laboratory Medicine (formerly AACC) annual meeting |
06/2023 - Present Abstract reviewer - Canadian Society of Clinical Chemists annual meeting |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Smy L, Shaw K, Smith A, Russell E, Van Uum S, Rieder M, Carleton B, Koren G. Hair cortisol as a novel biomarker of HPA suppression by inhaled corticosteroids in children. Pediatr Res. 2015 Jul;78(1):44-7. |
2. Smy L, Chan AC, Bozzo P, Koren G. Is it safe to use inhaled corticosteroids in pregnancy? Can Fam Physician. 2014 Sep;60(9):809-12, e433-5. PMCID: PMC4162695 |
3. Smy L, Shaw K, Amstutz U, Smith A, Berger H, Carleton B, Koren G. Hair cortisol as a hypothalamic-pituitary-adrenal axis biomarker in pregnant women with asthma: a retrospective observational study. BMC Pregnancy Childbirth. 2016 Jul 20;16(1):176. PMCID: PMC4955128 |
4. Smy L, Shaw K, Amstutz U, Staub M, Chaudhry S, Smith A, Carleton B, Koren G. Assessment of hair cortisol as a potential biomarker for possible adrenal suppression due to inhaled corticosteroid use in children with asthma: A retrospective observational study. Clin Biochem. 2018 Jun;56:26-32. |
5. Smy L. Imatininb mesylate: Should cancer drug be added to the list of therapeutic drugs to monitor? Clinical and Forensic Toxicology News (Quarterly, AACC/CAP). June 2018. |
6. Smy L, Straseski JA. Measuring estrogens in women, men, and children: Recent advances 2012-2017. Clin Biochem. 2018 Dec;62:11-23. |
7. Needham LL, Smy L, Lee MA, Kunzler TM, Genzen JR. Phlebotomy tube interference with nuclear magnetic resonance (NMR) lipoprotein subclass analysis. Clin Chim Acta. 2019 Jan;488:235-241. |
8. Smy L, Sadler AJ, McMillin GA. Evaluation of Imatinib Concentrations in Samples Submitted for BCR-ABL1 or Imatinib Testing-Evidence to Support Therapeutic Drug Monitoring for Dose Optimization? Ther Drug Monit. 2020 Aug;42(4):559-564. |
9. Smy L, De Biase I, Genzen JR, Yuzyuk T. The nuclear magnetic resonance metabolic profile: Impact of fasting status. Clin Biochem. 2021 Jan;87:85-92. |
Books, Chapters, and Reviews |
1. L Smy, K Apfeld, S Ampomah, M Thieme. "Management of Point-of-Care Testing." Clinical Laboratory Management 3rd ed., edited by Andrea Linscott, ASM Press, in press [CLM3-0037-2022R]. |
2. Smy L, Ledeboer NA, Wood MG. At-home testing for respiratory viruses: a minireview of the current landscape. J Clin Microbiol. 2024 May 08;62(5):e0031223. PMCID: PMC11077999 |
Non-Refereed Journal Publications/Original Papers |
1. Smy L, Kushnir MM, Frank EL. A high sensitivity LC-MS/MS method for measurement of 3-methoxytyramine in plasma and associations between 3-methoxytyramine, metanephrines, and dopamine. J Mass Spectrom Adv Clin Lab. 2021 Aug;21:19-26. PMCID: PMC8601001 |
Non-Peer Reviewed Educational Products |
1. A Grover and L Smy. K is for Kleihauer-Betke test: A brief review. Pediatric and Maternal-Fetal Division News. February 2023;42(1):2-4. |
