Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

CURRICULUM VITAE

Ling Mei MD
Associate Professor
Department of Medicine
Division of Gastroenterology

OFFICE ADDRESS:
Hub for Collaborative Medicine
8701 Watertown Plank Road
Milwaukee, WI 53226

EDUCATION:
07/1998 M.D., Shanghai Medical University, Shanghai, China
07/2001 M.S., Fu Dan University, Shanghai, China
06/2004 MPH, University of California, Los Angeles, Los Angeles, CA

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
07/1997 - 07/1998 Intern, Hua Shan Hospital, Shanghai Medical University, Shanghai, China
09/1998 - 07/2001 Residency, Internal Medicine, Hua Shan Hospital, Medical Center of Fu Dan University, Shanghai, China
11/2004 - 09/2006 Post Doctoral Research, Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, CA
09/2009 - 08/2012 Resident, Medicine, Internal Medicine, New York Downtown Hospital, New York, NY
08/2012 - 08/2015 Fellow, Medicine, Gastroenterology & Hepatology, Medical College of Wisconsin, Milwaukee, WI

FACULTY APPOINTMENTS:
09/2015 - Present Assistant Professor, Medicine, Gastroenterology & Hepatology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Wauwatosa, WI 53226
09/2015 - Present Faculty, Gastroenterology, Clement J. Zablocki VA Medical Center, 5000 W. National Ave, Milwaukee, WI 53214

HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:
09/2015 - Present Director, GI Motility Lab, Gastroenterology & Hepatology, Clement J. Zablocki VA Medical Center, Milwaukee, WI
09/2020 - Present Associate Director, GI Motility Lab, Medicine, Gastroenterology & Hepatology, Medical College of Wisconsin, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:
09/2015 - Present Staff Physician, Medicine, Gastroenterology & Hepatology, Froedtert Hospital, 9200 W. Wisconsin Ave., Milwaukee, WI 53226
09/2015 - Present Staff Physician, Froedtert Surgery Center, Milwaukee, WI
09/2015 - Present Staff Physician, Gastroenterology, Clement J Zablocki VA Medical Center, 5000 W. National Ave., Milwaukee, WI 53214

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
Internal Medicine
08/2012
08/2022
Gastroenterology
11/2015
11/2025
   
Certificates
Issued By Issue DateExpiration
Educational Commission for Foreign Medical Graduate
10/2008
None
    

AWARDS AND HONORS:
2006 Genetic Analysis Workshop 15 Scholarship
2016 - 2018 Certificate of Recognition for Scientific Accomplishments, AGA
2017 Department of Medicine Research Retreat Award, Early Career Faculty - Basic or Translational Research, Froedtert and the Medical College of Wisconsin
2018 Champion of Precision Medicine, Dept. of GI and Hep, Medical College of Wisconsin

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
2015 - Present American Gastroenterological Association (Member)
2015 - Present Society of Dysphagia (Member)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
2016 - Present Dysphagia
2018 - Present Plos One-Digestive System
2019 - Present Gastroenterology

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2015 - Present Member, Interview Committee Research and Clinical Fellowship Program, Medical College of Wisconsin
2015 - Present Member, Clinical Competency Committee of Gastroenterology Fellowship, Medical College of Wisconsin
2018 - 2020 Member, Precision Medicine Program, Medical College of Wisconsin
2019 - Present Member, Committee for Diversity and Inclusion, Department of Medicine, Medical College of Wisconsin
2021 Poster Judge, Department of Medicine, Research Retreat

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
Deglutitive and Airway Protective Functions of Proximal/Striated Muscle Esophagus in Health and Disease
Source:
NIH/NIDDK Grant# R01 DK132082
Role:
CO-I
Dates:
04/20/2022 - 02/28/2026
  
Non-Peer Review
Title:
Fecal Incontinence Ensemble
Source:
Clinical and Translational Science of Southeast Wisconsin
Role:
Lead Member
PI:
Reza Shaker, MD
Dates:
01/2020 - Present
Direct Funds:
$50,000
  
Title:
TAK 951-001 Biomarkers in CVS
Source:
Takeda
Role:
Principle Investigator
Dates:
09/2021 - Present
  
Title:
Concept Elicitation and Cognitive Interviews with Adult Patients with Cyclic Vomiting Syndrome (CVS)
Source:
Evidera
Role:
Principle Investigator
Dates:
09/2021 - Present
  
Pending
Non-Peer Review
Title:
A phase 3, Multicenter, Multinational, Randomized, Double-blinded, Placebo Controlled Induction and Maintenance Study To Evaluate The Efficacy and Safety Of CC-93538 In Adult and Adolescent Subjects With Eosinophilic Esophagitis
Source:
Celgene
Role:
PI
Dates:
03/2021 - 03/2024
  
Title:
Effects of clinical black raspberry supplementation on Helicobacter pylori eradication
Source:
Department of Agriculture
Role:
Co-Investigator
Dates:
09/2021 - 09/2026
Direct Funds:
$689,149
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Functional Bowel Disorders, DDW Review, Milwaukee, WI, 10/2016
Functional Anorectal Disorders, State of The Gut, Milwaukee, WI, 10/2017
Anorectal Disorder, State of The Gut, Milwaukee, WI, 10/2018
New Therapies in IBS, State of The Gut, Milwaukee, WI, 10/2019
Dietary Fiber in Gastrointestinal Health and Disease, Gastroenterology APP Monthly Meeting, Medical College of Wisconsin, Milwaukee, WI, 07/19/2021
Mei L, Siddique D, Motility, Research Seminar and Clinical Case Conference in Gastroenterology, Medical College of Wisconsin, Milwaukee, WI, 09/27/2021
Mei. L, Van Huis. A, Motility, Research Seminar and Clinical Case Conference in Gastroenterology, Medical College of Wisconsin, 03/21/2022
 
National
Familial Expression of Anti-Escherichia Coli Outer Membrane Porin C (OmpC) in Relatives of Patients with Crhohn's Disease, American Gastroenterological Association, Chicago, IL, 05/2005
Genetic Variation in BTLA is Strongly Associated with Crohn's Disease, American Gastroenterological Association, San Diego, CA, 05/2008
Characterization of Impedance Signature of Pharyngo-UES Bolus Transit: A Comparative Study with Fluoroscopy, Digestive Disease Week, San Diego, CA, 05/2016
Effect of Aging on UES Pressure Response to Slow and Ultra-slow Simulated Reflux Events: Not all is Lost with Aging, Digestive Disease Week, Chicago, IL, 03/2017
Contractile Segment Impedance (CSI)During High-resolution Impedance Manometry Highly Correlates with Intraluminal Baseline Impedance (BI), and is Inversely Related to Esophageal Acid Exposure, Digestive Disease Week, Washington DC, 06/2018
Live demonstration of anorectal manometry and esophageal manometry, American Neurogastroenterology and Motility Society Conference, Milwaukee, WI, 07/27/2018 - 07/29/2018
Isolated sub-UES striated esophageal peristalsis in response to slow simulated reflux events; effect of age and chemical composition, DDW, Virtual, 2021
Mei L, FURTHER CHARACTERIZATION OF ISOLATED STRIATED ESOPHAGUS CONTRACTION AS A UES FORTIFYING MECHANISM AGAINST PHARYNGEAL REFLUX, Digestive Disease Week, San Diego, CA, 05/21/2022 - 05/24/2022
Esophageal Imaging/Research on Reflexes between Esophagus and UES: Current Updates and Future Directions, 3rd WDS (World Dysphagia Summit), San Francisco, CA, 03/13/2023
 

PEER REVIEWED WORKSHOPS/PRESENTATIONS:
Regional
Mei L, Dua A, Kern M, Gao S, Edeani F, Dua K, Wilson A, Sanvanson P, Jadcherla S, Shaker R, Effect of aging on UES pressure response to slow and ultra-slow simulated reflux events: Not all is lost with aging, To be presented as a poster at Digestive Diseases Week 2017, Chicago, IL, 05/06/2017 - 05/09/2017
 

COMMITTEE SERVICE:
Medical College of Wisconsin
2015 - Present Department IRB reviewer
2018 - 2020 Member, Precision Medicine Program, Department of Medicine, Medical College of Wisconsin
2019 - Present Member, Diversity and Inclusion, Medical College of Wisconsin
2021 Poster judge, Research Retreat, Department of Medicine, Medical College of Wisconsin
 
Hospital
2015 - Present Clinical Competency Committee Member
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Student Education
10/2015 - Present Clinical Apprenticeship and Preceptor for Medical student M2/M3 (half day clinic per week)
 
Resident and Fellow Education
11/13/2019 Gastric Motor Disorder, Fellows Lecture, and Board Review
12/2019 Academic Half Day Lecture: Functional GI Disorders
02/2020 BST Mode Session on Gastroenterology
05/04/2020 Fatigability of External Anal Sphincter Muscles During Various Exercise Methods Using a Novel Strength Training Resistance Exercise Device, Monday Night Gastroenterology Conference
07/08/2020 Anorectal Manometry, Fellows Lecture, and Review Board
 

EXTRAMURAL TEACHING:
Medical Student Education
03/2001 - 05/2001 Hua Shan Hospital, Teaching Assistant Letured interns on the diagnosis and treatment of common digestive diseases.
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
Medical College of Wisconsin, 10/2015 - Present Clinical Apprenticeship
 
Clinical/Research Fellows
Francis Edeani, MD, Medical College of Wisconsin, 2016 - 2018 T32 Research Fellow, Resulted in accepted abstracts and manuscript (peer-reviewed publication #38, #42, #43), presentation at a national meeting, and faculty position at Medical College of Wisconsin
Shaina Lynch, MD, Medical College of Wisconsin, 06/2017 - 06/2019 T32 Research Fellow, Resulted in accepted abstracts, presentation at a national meeting
Karlo Kovacic, Medical College of Wisconsin, 2017 - Present T32 Research Fellow, Resulted in accepted abstracts, presentation at a national meeting, and faculty position at Children's Wisconsin
Krupa Patel, MD, Medical College of Wisconsin, 06/2019 - Present T32 Research Fellow, Resulted in accepted abstracts and manuscript (peer-reviewed publication #42), presentation at a national meeting
Elliot Yu, MD, Medical College of Wisconsin, 07/2020 - Present T32 Research Fellow, Resulted in accepted abstracts, presentation at a national meeting
 
Residents
Arshish Dua, Medical College of Wisconsin, 2015 - 2016 GI Research Rotation, Resulted in accepted abstracts and manuscript (peer-reviewed publication #35, #38), presentation at a national meeting
Kathan Chintamaneni, Medical College of Wisconsin, 2016, Accepted Abstract
Ghavesh Katbamna, Medical College of Wisconsin, 2020 GI Research Rotation
 
Clinical Staff
Benjamin Liu, Medical College of Wisconsin, 2021 - 2022 M4 Clinical Advisor
 

PROGRAMMATIC DEVELOPMENTS:
 
Research Programs
2015 - Present Mentor T32 trainees in the GI motility lab on the principles of esophageal and anorectal motility in normal individuals and on clinical motility disorders.
 
Clinical Programs
2015 - Present I help to re-establish and update the GI motility lab since I joined the faculty in VA.
 
 

LANGUAGE:
English, Chinese


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Lan Rong, Ling Mei, Wei Lu. Immunologic research of millimeter wave radiation on rats hepatoma. The 1st National Conference on the medical appliance of Millimeter Wave, 1999, 128-31
2. Rong L, Lu W, Sun DY, Mei L, Zhou BD. Effects of 33.6 GHz millimeter wave radiation on immune function of rats with DEN-induced hepatoma. Chin J Phys Med Rehabil, 2001; 23(1):29-31
3. Mei L, Lu W. Effects of Somatostatin on the diagnosis and treatment of gastrointestinal cancer. Foreign Medicine (volume of digestive disease), 2001, 21(2):90-4
4. Hu R, Zhai QW, He WJ, Mei L, Liu WY. Pegylation and its effect on the bioactivities and immunoreactivity of ricin. Intern J Biochem & Cell Biol, 2002, 34, 396-402
5. Jiang YB, Rong L, Mei L, Zhou BD, Lu W. Effect of millimeter wave radiation on apoptosis of human hepatoma cell. Chin J Digestion, 2002, 22(2): 103-6
6. Lu W, Zhou BD, Mei L, Sun D, Rong L. Expression of proliferating cell nuclear antigen, CDK4 and P16 in rat hepatocellular carcinoma by millimeter wave radiation. Chin J Digestion, 2002, 22(6): 357-60
7. Mei, L., Targan, S.R., Landers, C., Dutridge, D., Ippoloti, A., Vasiliauskas, E.A., Papadakis, K.A., Fleshner, P., Rotter, J.I., Yang, H.: Familial expression of anti-Escherichia coli outer membrane porin C (OmpC) in relatives of patients with Crohn’s disease, Gastroenterology, 130:1078-1085, April, 2006.
8. Schluender SJ, Mei L, Yang H, Fleshner PR. Can a meta-analysis answer the question: is mucosectomy and handsewn or double-stapled anastomosis better in ileal pouch-anal anastomosis? Am Surg. 2006 Oct;72(10):912-6.
9. Wilcox MA, Li Z, Tapper W, Browning S, Curtin K, Ding J, Ding Y, Gagnon F, He Q, Kuo TY, Li M, Matthew G, Mei L, Rao S, Shaw J, Wei Z, Yu Z, Zhang W, Zheng T, Zhu G. Genetic association with rheumatoid arthritis-Genetic Analysis Workshop 15: summary of contributions from Group 2. Genet Epidemiol. 2007;31 Suppl 1:S12-21.
10. Papadakis, KA, Yang,H, Ippoliti, A, Mei, L, Elson, CO, Hershberg RM, Vasiliauskas, EA, Fleshner, PR, Abreu, MT, Taylor, K, Landers, CJ, Rotter, JI, Targan, SR. Anti-Flagellin (Cbir1) phenotypic and genetic Crohn’s disease association. Inflamm Bowel Dis. 2007 Jan 26;13(5):524-530
11. Devlin, S.M., Yang, H., Ippoliti, A., Taylor, K.D., Landers, C.J., Su, XW, Abreu, M.T., Papadakis, K., Vasiliauskas, E, Melmed, G., Fleshner, P., Mei, L., Rotter, J.I., Targan, S.R. NOD2/CARD15 variants are significantly associated with sero-reactivity to microbial antigens in patients with Crohn’s disease and their unaffected relatives. Gastroenterology. 2007 Feb;132(2):576-86.
12. Su, X., Lee, L., Li, X., Lu, J., Hu, Y., Zhan, S., Cao, W., Mei, L., Tang, Y., Wang, D., Krauss, R., Rotter, J.I., Yang, H.: Association between angiotensin I receptor genes and blood pressure response to an ACE inhibitor. Circulation. 2007 Feb 13;115(6):725-32.
13. Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet. 2007 May;39 (5):596-604.
14. Fleshner,P.,Ippoliti, A., Dubinsky, M., Ognibene, S., Vasiliauskas, E., Chelly, M., Mei, L., Papadakis, KA., Landers, C., Targan,S.. A prospective multivariate analysis of perioperative clinical factors associated with pouchitis after Ileal Pouch-Anal Anastomosis. Clin Gastroenterol Hepatol. 2007 Aug;5(8):952-8
15. Picornell Y, Mei L, Taylor K, Yang H, Targan SR, Rotter JI. TNFSF15 is an ethnic-specific IBD gene. Inflamm Bowel Dis. 2007 Nov;13(11):1333-8. PMCID: PMC2552994
16. Schluender SJ, Ippoliti A, Dubinsky M, Vasiliauskas EA, Papadakis KA, Mei L, Targan SR, Fleshner PR. Does infliximab influence surgical morbidity of ileal pouch-anal anastomosis in patients with ulcerative colitis? Dis Colon Rectum. 2007 Nov;50(11): 1747-53
17. Mei L., Li X., Yang K., Cui J., Fang B., Guo X., Rotter JI. Gene-gene interaction and gene-smoking interaction in Rheumatoid Arthritis. BMC Proc. 2007 Dec, 1(suppl 1):S17
18. Dubinsky, M., Kugathsan, S., Mei, L., Picornell, Y., Nebel, J., Wrobel, I., Quiros, A., Silber, G., Wahbeh, G., Katzir, L., Vasiliauskas, E., Bahar, R., Otley, A., Mack, D., Evans, J., Rosh, J., Oliva, H.M., Leleiko, N., Crandall, W., Langton, C., Taylor, K., Targan, S., Rotter, J., Markowitz, J., Hyams, J. for the Western Regional Pediatric IBD Research Alliance, Pediatric IBD Collaborative Research Group and the Wisconsin Pediatric IBD Alliance: Increased immune reactivity predicts aggressive complicating Crohn’s disease in children, Clinical Gastroenterology and Hepatology, 2008, 6(10):1105-11
19. Fleshner P, Ippoliti A, Dubinsky M, Vasiliauskas E, Mei L, Papadakis KA, Rotter JI, Landers C, Targan S. Both preoperative perinuclear antineutrophil cytoplasmic antibody and anti-CBir1 expression in ulcerative colitis patients influence pouchitis development after ileal pouch-anal anastomosis. Clin Gastroenterol Hepatol. 2008 May;6(5):561-8. PMCID: PMC2742560
20. Taylor KD, Targan SR, Mei L, Ippoliti AF, McGovern D, Mengesha E, King L, Rotter JI. IL23R haplotypes provide a large population attributable risk for Crohn's disease. Inflamm Bowel Dis. 2008 Sep;14(9):1185-91. PMCID: PMC2574614
21. Saruta, M., Targan, S.R., Mei, L., Ippoliti, A.F., Taylor, K.D., Rotter, J.I.: High frequency haplotypes in the X-chromosome locus TLR8 are associated with both CD and UC in females, Inflammatory Bowel Diseases, 2009;15(3):321-7.
22. Takedatsu, H., Taylor, K.D., Mei, L., McGovern, D.P., Landers, C.J., Gonsky, R., Cong, Y., Vasiliauskas, E.A., Ippoliti, A., Elson, C.O., Rotter, J.I., Targan, S.R.: Linkage of CD-related serological phenotypes: NFKB1 haplotypes are associated with anti-CBir1 and ASCA, and show reduced NF-B activation, Gut, 58:60-67, 2009
23. Mundwiler ML, Mei L, Landers CJ, Reveille JD, Targan S, Weisman MH. Inflammatory bowel disease serologies in ankylosing spondylitis patients: a pilot study. Arthritis Res Ther. 2009;11(6):R177. PMCID: PMC3003540
24. Markowitz J, Kugathasan S, Dubinsky M, Mei L, Crandall W, Leleiko N, Oliva-Hemker M, Rosh J, Evans J, Mack D, Otley A, Pfefferkorn M, Bahar R, Vasiliauskas E, Wahbeh G, Silber G, Quiros JA, Wrobel I, Nebel J, Landers C, Picornell Y, Targan S, Lerer T, Hyams J. Age of diagnosis influences serologic responses in children with Crohn's disease: A possible clue to etiology? Inflamm Bowel Dis. 2009 May;15(5):714-9.
25. Michelsen, K.S., Thomas, L.S., Taylor, K.D., Yu, Q.T., Mei, L., Landers, C.J., Derkowski, C., McGovern, D.P., Rotter, J.I., Targan, S.R.: IBD-associated TL1a (TNFSF15) haplotypes determine increased expression of TL1A protein, PLoS One. 2009;4(3):e4719.
26. McGovern, D.P.B., Taylor, K.D., Landers, C., Derkowski, C., Dutridge, D., Dubinsky, M., Ippoliti, A., Vasiliauskas, E., Mei, L., Mengesha, E., King, L., Pressman, S., Targan, S.R., Rotter, J.I.: MAGI2 genetic variation and inflammatory bowel disease (IBD), Inflammatory Bowel Diseases, 2009,15(1):75-83.
27. McGovern, D.P.B., Rotter, J.I., Mei, L., Haritunians, T., Landers, C., Derkowski, C., Dutridge, D., Dubinsky, M., Ippoliti, A., Vasiliauskas, E., Mengesha, E., King, L., Pressman, S., Targan, S.R., Taylor, K.D.: Genetic epistasis of IL23/IL17 pathway genes in Crohn’s disease, Inflammatory Bowel Disease, 2009 Jun;15(6):883-9.
28. Hollenbach JA, Ladner MB, Saeteurn K, Taylor KD, Mei L, Haritunians T, McGovern DP, Erlich HA, Rotter JI, Trachtenberg EA. Susceptibility to Crohn's disease is mediated by KIR2DL2/KIR2DL3 heterozygosity and the HLA-C ligand. Immunogenetics. 2009 Oct;61(10):663-71. PMCID: PMC2813946
29. Li X, Mei L, Yang K, Rotter JI, Guo X. Identifying association under a previous linkage peak on chromosome 16 for body mass index using cross-sectional and longitudinal data of the Framingham Heart Study. BMC Proc. 2009 Dec 15;3 Suppl 7(Suppl 7):S101. PMCID: PMC2795872
30. Dubinsky MC, Mei L, Friedman M, Dhere T, Haritunians T, Hakonarson H, Kim C, Glessner J, Targan SR, McGovern DP, Taylor KD, Rotter JI. Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2010 Aug;16(8):1357-66. PMCID: PMC2889173
31. Ippoliti A, Devlin S, Mei L, Yang H, Papadakis KA, Vasiliauskas EA, McGovern DP, Abreu MT, Melmed G, Shaye O, Enayati P, Chen G, Choi J, Taylor K, Landers CJ, Rotter JI, Targan SR. Combination of innate and adaptive immune alterations increased the likelihood of fibrostenosis in Crohn's disease. Inflamm Bowel Dis. 2010 Aug;16(8):1279-85. PMCID: PMC3875376
32. Shih DQ, Nguyen M, Zheng L, Ibanez P, Mei L, Kwan LY, Bradford K, Ting C, Targan SR, Vasiliauskas EA. Split-dose administration of thiopurine drugs: a novel and effective strategy for managing preferential 6-MMP metabolism. Aliment Pharmacol Ther. 2012 Sep;36(5):449-58.
33. Jiao H, Mei L, Sharma T, Kern M, Sanvanson P, Shaker R. A human model of restricted upper esophageal sphincter opening and its pharyngeal and UES deglutitive pressure phenomena. Am J Physiol Gastrointest Liver Physiol. 2016 Jul 01;311(1):G84-90. PMCID: PMC4967170
34. Jiao H, Mei L, Liang C, Dai Y, Fu Z, Wu L, Sanvanson P, Shaker R. Upper esophageal sphincter augmentation reduces pharyngeal reflux in nasogastric tube-fed patients. 2017 Oct 8. doi: 10.1002/lary.26895.
35. Mei L, Jiao H, Sharma T, Dua A, Sanvanson P, Jadcherla SR, Shaker R. Comparative effect of the sites of anterior cervical pressure on the geometry of the upper esophageal sphincter high-pressure zone. Laryngoscope. 2017 Nov;127(11):2466-2474. PMCID: PMC5654682
36. Balasubramanian G, Sharma T, Kern M, Mei L, Sanvanson P, Shaker R. Characterization of pharyngeal peristaltic pressure variability during volitional swallowing in healthy individuals. Neurogastroenterol Motil. 2017 Nov;29(11). PMCID: PMC6757324
37. Xu X, Li C, Gao X, Xia K, Guo H, Li Y, Hao Z, Zhang L, Gao D, Xu C, Xu H, Xiong Z, Qiu Z, Mei L, Xie X, Ruan K, Hu R, Excessive UBE3A dosage impairs retinoic acid signaling and synaptic plasticity in autism spectrum disorders, Cell Res. 2018 Jan;28(1):48-68, PMID: 29076503
38. Mei L, Dua A, Kern M, Gao S, Edeani F, Dua K, Wilson A, Lynch S, Sanvanson P, Shaker R. Older Age Reduces Upper Esophageal Sphincter and Esophageal Body Responses to Simulated Slow and Ultraslow Reflux Events and Post-Reflux Residue. Gastroenterology. 2018 Sep;155(3):760-770.e1. PMCID: PMC6120791
39. Sanvanson P, Li Z, Mei L, Kounev V, Kern M, Ward BD, Medda B, Shaker R. Interplay of spinal and vagal pathways on esophageal acid-related anterior cingulate cortex functional networks in rats. Am J Physiol Gastrointest Liver Physiol. 2019 May 01;316(5):G615-G622. PMCID: PMC6580238
40. Wang L, Echeveste CE, Yu J, Huang Y, Lechner J, Mei L, Sanvanson P, Yearsley M, Wang C, Stoner G. Can Natural Products Suppress Resistant Helicobacter pylori to Fight Against Gastric Diseases in Humans? eFood 2020 Feb;1(1):53-60 PMID: 34308385
41. Boschuetz N, Cheng S, Mei L, Loy VM. Changes in Alcohol Use Patterns in the United States During COVID-19 Pandemic. WMJ. 2020 Sep;119(3):171-176.
42. Mei L, Patel K, Lehal N, Kern MK, Benjamin A, Sanvanson P, Shaker R. Fatigability of the external anal sphincter muscles using a novel strength training resistance exercise device. Am J Physiol Gastrointest Liver Physiol. 2021 Apr 01;320(4):G609-G616. PMCID: PMC8238165
43. Patel K, Mei L, Yu E, Kern M, Lehal N, Edeani F, Sanvanson P, Davidson ERW, Shaker R. Differences in fatigability of muscles involved in fecal continence: Potential clinical ramifications. Physiol Rep. 2021 Dec;9(24):e15144. PMCID: PMC8685596
44. Edeani F. Kern, M. Ulualp, K. Kovacic, K. Sanvanson, P. Mei, L. Shaker, R. Variables influencing manometric parameters of deglutitive and non-deglutitive upper esophageal sphincter: A study of 89 asymptomatic participants, Neurogastroenterol Motil. 2022 Feb;34(2):e14175, PMID: 34431179
45. Edeani F, Sanvanson P, Mei L, Agrawal D, Kern M, Kovacic K, Shaker R. Effect of inter-swallow interval on striated esophagus peristalsis; a comparative study with smooth muscle esophagus. Neurogastroenterol Motil. 2023 Aug;35(8):e14608. PMCID: PMC10789016
 
Books, Chapters, and Reviews
1. Ling Mei, Patrick Sanvanson (2017). UES restrictive disorders. In Barden, E, Shaker, R (Ed), Gastrointestinal Motility Disorders. A point of care clinical guide. (pp79-90.)Springer International Publishing
 
Abstracts
1. Mei L, Landers C, Dutridge D, Ippoliti A, Vasiliauskas EA, Papadakis KA, Fleshner P, Targan SR, Rotter JI, Yang H. Familial expression of anti-Escherichia coli outermembrane porin C (OmpC) in relatives of patients with Crohn’s disease, Gastroenterology,128(S2): A2, April, 2005. Presented (oral) to the annual meeting of the American Gastroenterological Association, Chicago, May 15-18, 2005.
2. Mei L, Picornell Y, Gregory F, Mera R, Wang D, Dutridge D, Rotter, JI, Torres EA, Yang H. Association between ancestry proportion and inflammatory bowel disease in Puerto Ricans. Gastroenterology, 130(Suppl 2):A587, April, 2006. Presented to the annual meeting of the American Gastroenterological Association, Los Angeles, May 21-24, 2006.
3. Mei L, Torres EA, Picornell Y, Su X, Gregory F, Mera R, Nieves PJ, Dutridge D, Taylor K, Yang H, Rotter JI: CARD8 is associated with Crohn’s disease in the Puerto Rico population. American Journal of Human Genetics, 2006. Presented to the annual meeting of the American Society of Human Genetics, New Orleans, October 9-14, 2006.
4. Mei L, Su X, Ippoliti AF, Taylor KD, Targan S, Rotter JI: Association between IL17A and IL17RA genes and inflammatory bowel diseases (IBD). Gastroenterology, 2007. Presented to the annual meeting of the American Gastroenterological Association, Washington, DC, May 19-24, 2007.
5. Mei L, Taylor KD, McGovern D, Picornell Y, Su X, Landers CJ, Targan SR, Rotter,JI. Variants in genes related to innate (NOD2, TLR5) and adaptive (TNFSF15/TL1A)immune pathways combine to increase the magnitude of anti-OMPC expression in Jewish CD subjects. Gastroenterology, 2008. Presented to the annual meeting of the American Gastroenterological Association, San Diego, May 17-22, 2008.
6. Mei L, Taylor KD, Landers CJ, McGovern D, Targan SR, Rotter JI. Genetic variation in BTLA is strongly associated with Crohn’s disease. Gastroenterology, 2008. Presented (oral) to the annual meeting of the American Gastroenterological Association, San Diego, May 17-22, 2008.
7. Mei L, Taylor KD, McGovern D, Targan S, Rotter JI. Association between IL17RD gene and Crohn’s disease and gene-gene interaction in the IL23-IL17 pathway. American Journal of Human Genetics: A416, 2008. Presented to the annual meeting of the American Society of Human Genetics, Philadelphia, November 11-15, 2008.
8. Mei L, Vendrell R, Cruz A, Ortiz Z, Rabell N, Rivera M, Rivera C, Salas M, Dutridge D, Landers C, Targan S, Rotter JI, Taylor KD, Torres EA. Childhood hygiene shifts serological profiles in adult CD. Gastroenterology, 2009. Presented to the annual meeting of the American Gastroenterological Association, Chicago, May 30-June 3, 2009.
9. Sharma T, Babaei A, DeMara-Hoth M, Mei L, Sanvanson PP, Kern M, Jiao H, Shaker R. Effect of Neck Positions, Bolus Volume and Body Posture on High Resolution Pharyngo- UES Manometry. May 2013 Gastroenterology, Vol. 144, Issue 5, S-785
10. Sanvanson PP, Kounev V, Mei L, Li R, Hyde JS, Medda BK, Shaker R. Esophageal Acid Induced Brain Functional Connectivity Changes Are Vagally Mediated. May 2013 Gastroenterology, Vol. 144, Issue 5, S-562–S-563
11. Fang, T., Mei, L., Dua, KS. Correlation of Degree of Dysphagia with Endoscopic Ultrasound T-stage of Esophageal Cancer. Presented to DDW2013, Orlando, May 17-22, 2013
12. Mei L, Kounev V, Sanvanson PP, Li R, Li SJ, Medda BK, Shaker R. Effect of Vagotomy on Cortical FMRI Activity Induced by Esophageal Acid Stimulation in Rats: Further Validation of the Model. May 2013 Gastroenterology, Vol. 144, Issue 5, S-558
13. Mei L, Jiao H, Sharma T, Sanvanson P, Jadcherla SR, Shaker R. Effect of External Anterior Cervical Pressure Location on the UES High-Pressure Zone Is Site Specific. May 2014 Gastroenterology, Vol. 146, Issue 5, S-895–S-896
14. Babaei A, Jiao H, Mei L, Kern M, Shaker R. Correlation of Externally Applied Cricoid Pressure With Luminal Upper Esophageal Sphincter Pressure Augmentation; Effect of Posture and Technique. May 2014 Gastroenterology, Vol. 146, Issue 5, S-856
15. Mei L, Sanvanson P, Kounev V, Li R, Medda BK, Shaker R. Effect of Chronic Esophageal Acid Exposure and Acute Acid Re-Challenge on Functional Connectivity of Anterior Cingulate Cortex in Rats. May 2014 Gastroenterology, Vol. 146, Issue 5, S-846
16. Kern M, Babaei A, Siwiec RM, Samuel EA, Mei L, Sanvanson P, Shaker R. Differences in Amygdala Functional Connectivity Between Erosive (ERD) and Non-Erosive Reflux Disease (NERD) Patients During Esophageal Acid Exposure. May 2014 Gastroenterology, Vol. 146, Issue 5, S-844
17. Sanvanson P, Mei L, Kounev V, Li R, Hyde JS, Medda BK, Shaker R. Functional Connectivity of Somatosensory Cortex Is Enhanced by Acute Esophageal Acid Exposure in Rats. May 2014 Gastroenterology, Vol. 146, Issue 5, S-844–S-845
18. Sharma T, Mei L, Jiao H, Shaker R. Nadir UES Relaxation and Hypopharyngeal Intra Bolus Pressures Are More Sensitive to Consistency and Viscosity Challenge Than Pharyngeal Peristalsis Parameters Measured by High Resolution Manometry. May 2014 Gastroenterology, Vol. 146, Issue 5, S-78
19. Jiao H, Mei L, Babaei A, Sharma T, Sanvanson P, Kern M, Jadcherla SR, Shaker R. A Human Model of Restricted UES Opening and Its Characteristic Pharyngeal and UES Deglutitive Pressure Phenomena. May 2014 Gastroenterology, Vol. 146, Issue 5, S-77
20. Rage A, Seamon AR, Mohorek MR, Mei L, Massey BT. A Rapid Initial Lag Phase of Gastric Emptying Is Associated With a Greater Degree of Obesity and Weight Gain Over Time. April 2015 Gastroenterology, Vol. 148, Issue 4, S-669
21. Shaker R, Balasubramanian G, Babaei A, Manderle R, Mei L, Kern M. Effect of a Novel “Resistance Exercise Device” for Swallowing on Pharyngeal Peristalsis. April 2015 Gastroenterology, Vol. 148, Issue 4, S-168–S-169
22. Balasubramanian G, Kern M, Mei L, Maderle R, Babaei A, Shaker R. Variability of Pharyngeal Peristaltic Pressure Parameters Measured by High Resolution Manometry (HRM); A Study of Over 900 Pressure Signatures. April 2015 Gastroenterology, Vol. 148, Issue 4, S-167
23. Balasubramanian G, Kern M, Manderle R, Mei L, Sanvanson P, Babaei A, Shaker R. Dynamics of Pharyngeal Contraction During Vocalization, Cough and Swallowing Maneuvers Using High Resolution Manometry. April 2015 Gastroenterology, Vol. 148, Issue 4, S-895
24. Kern M, Balasubramanian G, Mei L, Manderle R, Babaei A, Shaker R. Inter-Rater Agreement for Analysis of Pharyngeal High Resolution Manometry Parameters. April 2015 Gastroenterology, Vol. 148, Issue 4, S-896
25. Mei L, Balasubramanian G, Manderle R, Kern M, Sanvanson P, Jiao H, Shaker R. Pharyngeal Bolus Transit in a Human Model of Restricted Swallowing; A Multi-Channel Intraluminal Impedance Study. April 2015 Gastroenterology, Vol. 148, Issue 4, S-895
26. Mei L, Sanvanson P, Balasubramanian G, Kern M, Wuerl A, Shaker R. Characterization of Impedance Signature of Pharyngo-UES Bolus Transit: A Comparative Study With Fluoroscopy. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S96.
27. Kern M, Sanvanson P, Mei L, Wuerl A, Shaker R. Differences in Resting State Connectivity of the Homeostatic Interoceptive Network in Erosive as Well as Non-Erosive GERD Patients and Healthy Controls. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-107 - S-108
28. Hongmei J, Mei L, Liang C, Dai Y, Fu Z, Wu L, Sanvanson P, Shaker R. UES Assist Device Reduces the Aspiration Risk By Decreasing Trans-UES Reflux of Gastric Content in Long-Term Nasogastric Tube Fed Patients: A Combined pH-Multichannel Intraluminal Impedance Study. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-110 - S-111
29. Kern M, Balasubramanian G, Sanvanson P, Mei L, Wuerl A, Hyngstrom A, Shaker R. Augmenting the Training Effect of a Swallow Resistance Exercise Device (sRED): Lessons From Exercise Physiology. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-860
30. Kern M, Balasubramanian G, Sanvanson P, Mei L, Wuerl A, Shaker R. Biomechanical Evidence of UES Opening Muscle Fatigue Induced by Resistance to Deglutitive Hyo-Laryngeal Excursion. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-860
31. Kern, M. Balasubramanian G, Sanvanson P, Mei L, Wuerl A, Shaker R. Characterization of the Biomechanical Effects of Externally Applied Resistance to Deglutitive Hyo-Laryngeal Excursion. April 2016 Gastroenterology, Vol. 150, Issue 4, S-859 - S-860
32. Kern M, Balasubramanian G, Sanvanson P, Mei L, Wuerl A, Shaker R. Safety of Restricting the Deglutitive Hyo-Laryngeal Excursion for Overloading and Strength Training of Swallow Muscles. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-861
33. Sanvanson P, Sobin M, Balasubramanian G, Mei L, Wuerl A, Kern M, Shaker R. Effect of Repeated Swallows Against Resistance on Proximal Striated Muscle Segment of Esophagus in the Elderly. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-293 - S294
34. Gao S, Kern M, Balasubramanian G, Sanvanson P, Mei L, Hyngstrom A, Shaker R. Effect of Repeated Swallowing Against Laryngeal Resistance on the Deglutitive Trajectories of the Hyoid and Larynx; A Study of Post-contraction Relaxation Velocity. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-862
35. Sanvanson P, Li Z, Mei L, Kounev V, Medda BK, Ward BD, Kern M, Shaker R. A Novel Method for Characterizing Cerebral Response to Esophageal Acid Exposure by fMRI and fcMRI. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-527-S528
36. Sanvanson P, Li Z, Mei L, Kounev V, Medda BK, Ward BD, Kern M, Shaker R. Alterations of Thalamic Networks in Response to Esophageal Acid Infusion: A Functional Connectivity Study in Rats. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-528
37. Mei L, Dua A, Kern M, Gao S, Edeani F, Dua K, Wilson A, Sanvanson P, Jadcherla S, Shaker R. Effect of aging on UES pressure response to slow and ultra-slow simulated reflux events: Not all is lost with aging. To be presented as a poster at Digestive Diseases Week 2017.
38. Kern M, Balasubramanian G, Sanvanson P, Mei L, Agrawal D, Shaker R. Feasibility and testing of group HRM isocontour maps as a means to facilitate comparison across individuals and conditions: Development of a learning comparative "ManoBank." To be presented as a poster at Digestive Diseases Week 2017.
39. Agrawal D, Kern M, Stevens S, Dulitz L, Dummer T, Monday A, Antinoja J, Wilson A, Balasubramanian G, Edeani F, Mei L, Sanvanson P, Shaker R. Strength training using a novel Swallow Resistance Exercise Device (sRED) improves oropharyngeal swallow function, deglutitive UES opening, and biomechanics in a heterogeneous group of dysphagic patients. To be presented as a poster at Digestive Diseases Week 2017.
40. Sanvanson P, Mei L, Li Z, Kounev V, Medda B, Shaker R. Interplay of spinal and vagal pathways on the esophageal acid-related anterior cingulate cortex functional networks in rats. To be presented as a poster at Digestive Diseases Week 2017.
41. Agrawal D, Kern M, Gao S, Wilson A, Edeani F, Mei L, Sanvanson P, Shaker R. Reversal of pharyngeal constrictor sarcopenia by resistance strength training exercise in the elderly. To be presented as a poster at Digestive Diseases Week 2017.
42. Agrawal D, Kern M, Wilson A, Ulualp K, Li Z, Balasubramanian G, Edeani F, Mei L, Sanvanson P, Shaker R. Effect of a novel strength training exercise technique on pharyngeal phase of swallowing musculature in the elderly: A case for developing preventative swallow health maintenance exercise program in geriatric population. To be presented as a poster at Digestive Diseases Week 2017.
43. Kern M, Sanvanson P, Li Z, Wilson A, Mei L, Shaker R. Comparison of brain function during normal swallow and swallow against resistance: The effect of effort. To be presented as a poster at Digestive Diseases Week 2017.
44. Mei L, Sanvanson P, Li Z, Medda B, Shaker R. Chronic esophageal acid exposure modifies functional connectivity of anterior cingulate cortex during acute acid challenge in rats. To be presented as a poster at Digestive Diseases Week 2017.
45. Mei L, Sanvanson P, Jiao H, Shaker R. Manometric characteristics of esophageal striated muscle contractility in a human model of restricted upper esophageal sphincter opening. To be presented as a poster at Digestive Diseases Week 2017.
46. Edeani F, Ulualp K, Sanvanson P, Mei L, Agrawal D, Kern M, Wilson A, Dua A, Shaker R. Effect of experimental perturbation of pharyngeal phase of swallowing on esophageal motor function. To be presented as a poster at Digestive Diseases Week 2017.
47. Kern M, Edeani FO, Lynch SM, Sanvanson P, Mei L, Crumb C, Shaker R. Spatial Intra-Luminal Pressure Gradient and Variance of Esophageal Pressure Magnitudes in Achalasia Sub-Types and Healthy Controls. May 2018. Gastroenterology, Vol. 154, Issue 6, S-738–S-739
48. Edeani FO, Sobin M, Saeian S, Mei L, Kern M, Sanvanson P, Shaker R. Examining the Deglutitive Integrated Relaxation Pressure (IRP) of the Lower Esophageal Sphincter (LES) in 60 Healthy Asymptomatic Controls and 69 Achalasia Patients. May 2018. Gastroenterology, Vol. 154, Issue 6, S-739.
49. Kern M, Edeani FO, Lynch SM, Sanvanson P, Mei L, Crumb C, Shaker R. Agglomerative Hierarchical Clustering of Esophageal Body Manometric Isocontour Data: Similartities and Differences Across Four Patient Groups and Healthy Subjects. May 2018 Gastroenterology, Vol. 154, Issue 6, S-971.
50. Kern M, Edeani FO, Sanvanson P, Mei L, Lynch SM, Crumb C, Shaker R. An Esophageal “Manobank”: Feasibility and Testing of Group HRM Isocontour Pressure Maps of Centrality and Dispersion to Facilitate Comparison Across Individuals and Conditions. May 2018 Gastroenterology, Vol. 154, Issue 6, S-970–S-971.
51. Edeani FO, Kern M, Sanvanson P, Mei L, Ulualp K, Crumb C, Cheng CY, Shaker R. Effects of Position, Age, Gender, and Number of Swallows on Multiple Rapid Swallow (MRS)-Induced Peristaltic Augmentation of the Distal Esophagus. May 2018 Gastroenterology, Vol. 154, Issue 6, S-739.
52. Edeani FO, Kern M, Sobin M, Sanvanson P, Lynch SM, Mei L, Crumb C, Cheng CY, Shaker R. Effect of Aging on Deglutitive Lower Esophageal Sphincter Integrated Relaxation Pressure. May 2018 Gastroenterology, Vol. 154, Issue 6, S-966.
53. Edeani FO, Ulualp K, Kern M, Kovacic K, Sanvanson P, Mei L, Shaker R. Manometric Parameters of Deglutitive upper Esophageal Sphincer Across Age Spectrum: A Study of 87 Healthy Participants. May 2018 Gastroenterology, Vol. 154, Issue 6, S-13.
54. Kern M, Edeani FO, Lynch SM, Sanvanson P, Mei L, Crumb C, Shaker R. Machine Learning Techniques for Classifying High Resolution Manometric Isocontours. May 2018 Gastroenterology, Vol. 154, Issue 6, S-738.
55. Shaker R, Edeani FO, Agrawal D, Mei L, Lynch SM, Wilson A, Crumb C, Sanvanson P. A Single Combined Manometry and Perfusion Catheter for Studying the Upper Esophageal Sphincter Competency: UES Stress Test Catheter. May 2018 Gastroenterology, Vol. 154, Issue 6, S-473–S-474.
56. Edeani FO, Sanvanson P, Kovacic K, Lynch SM, Mei L, Crumb C, Kern M, Shaker R. Comparison Between the Effect of Swallow Interval on Striated and Smooth Muscle Esophagus Peristalsis. May 2018 Gastroenterology, Vol. 154, Issue 6, S-966.
57. Kern M, Edeani FO, Lynch SM, Sanvanson P, Mei L, Crumb C, Shaker R. Ineffective Esophageal Motility Manometric Isocontour Analysis: Spatiotemporal Differences from Healthy Controls. May 2018 Gastroenterology, Vol. 154, Issue 6, S-971–S-972.
58. Mei L. Babaei A. Contractile Segment Impedance (CSI) During High-Resolution Impedance Manometry Highly Correlates with Intraluminal Baseline Impedance (BI), and is Inversely Related to Esophageal Acid Exposure. May 2018 Gastro 154(6): S85
59. Mei L, Kern M, Edeani F, Wilson A, Sanvanson P, Shaker R. The Effect of Aging on Esophago-UES Relaxation Response Induced by Rapid Esophageal Air Distention. Accepted Poster DDW 2019
60. Mei L, Lynch S, Kovacic K, Crumb C, Shaker R. Variation of Basal UES Pressure within 2-minute Interval while Refraining Swallow. Accepted Poster DDW 2019.
61. Kern M, Edeani F, Kovacic K, Sanvanson P, Mei L, Crumb C, Shaker R. Aberrant Striated Muscle Contractility in Symptomatic Patients with Normal Esophageal Manometry. Accepted Poster DDW 2019.
62. Kern M, Agrawal D, Edeani F, Sanvanson P, Mei L, Shaker R. Effects of Strength Training on Deglutitive Pharyngeal Pressure Maps in Healthy Elderly Subjects. Accepted Poster DDW 2019
63. Kovacic K, Mei L, Lynch S, Kern M, Nelson, Crumb C, Shaker R. Effect of Acute Esophageal Acid Exposure on Striated Muscle Esophagus and UES Relaxation. Accepted Poster DDW 2019.
64. Lynch S, Agrawal D, Mei L, Sanvanson P, Kern M, Shaker R. Initial Gains by Swallowing Against Laryngeal Restriction (SALR) Exercise in Dysphagic Patients Requires Maintenance Regimen to Sustain Effects. Accepted Poster DDW 2019
65. Lynch S, Agrawal D, Mei L, Sanvanson P, Kern M, Shaker R. Swallowing against Laryngeal Restriction (SALR) Exercise Technique Significantly Increases the Duration and Diameter of UES Opening in Both Healthy Elderly and Dysphagic Patients. Accepted Poster DDW 2019
66. Zhang N, Liang C, Wu I, Lu W, Sun D, Mei L, Jiao H. MANOMETRIC CHARACTERISTICS OF UPPER ESOPHAGEAL SPHINCTER AND STRIATED ESOPHAGEAL CONTRACTILITY IN PATIENTS WITH INEFFECTIVE ESOPHAGEAL MOTILITY
67. Edeani FO, Saeian S, Kern M, Kovacic K, Mei L, Sanvanson P, Shaker R. Rapid Drinking Challenge May Help Distinguish Opioid-Associated Esophageal Dysmotility. Accepted DDW 2019 Poster
68. Mei L, Patel K, Lehal N, Kern M, Benjamin A, Sanvanson P, etc., Sa1692 Fatigability of External Anal Sphincter Muscles During Various Exercise Methods Using a Novel Strength Training Resistance Exercise Device, Gastroenterology, Vol. 158, Issue 6, Supplement, S-385, Published in issue: May, 2020
69. Patel K, Mei L, Lehal N, Benjamin A, Sanvanson P, Kern M, etc. Sa1698 External Anal Sphincter Strength Training Exercise Using a Novel Continence Muscles Resistance Exerciser Device Results in Improved Anal Sphincter Contractility in Patients with Fecal Incontinence, Gastroenterology, Vol. 158, Issue 6, Supplement, S-388, Published in issue: May, 2020
70. Patel K, Mei L, Kern M, Sanvanson P, Lehal N, Edeani F, etc., Sa1699 Geometric Characteristics of the Anal Canal High-Pressure Zone During Repetitive Contraction Against a Resistive Load Can Help Define the Fatigability of Muscles Involved in Fecal Continence, Gastroenterology, Vol. 158, Issue 6, Supplement, S-388, Published in issue: May, 2020
71. Li J, Li L, Fu Z, Liu M, Mei L, Jiao H, Su 1360 The Effect of Proton Pump Inhibitor on the Image Quality of Magnetically Controlled Capsule Endoscopy in Aging Patients, Gastroenterology, Vol. 158, Issue 6, Supplement, S-565, Published in issue: May, 2020
72. Mei L, Edeani F, Sanvanson P, Kern M, Shaker R, 695 Isolated Sub-Ues Striated Esophageal Peristalsis in Response to Slow Simulated Reflux Events: Effect of Age and Chemical Composition, Gastroenterology, Vol. 160, Issue 6, Supplement, S-140-S-141, Published in issue: May, 2021
73. Kern M, Sanvanson P, Mei L, Edeani F, Agrawal D, Patel K, etc., Sa191 Normalized Impedance Isocontour Data in Patients with Ineffective Esophageal Motility (IEM) Exhibit Bolus Retention Proximal Esophagus as well as Globally Lower Baseline Impedance Values Compared to Healthy Controls, Gastroenterology, Vol. 106, Issue 6, Supplement, S-459, Published in issue: May, 2021
74. Kern M, Sanvanson P, Mei L, Edeani F, Agrawal D, Patel K, etc., Sa192 Patients with Diagnosis of IEM and those with Swallowing Complaint but Normal Manometry have Significantly Different Deglutitive Straited Esophagus Flow Dynamics Compared to Healthy Controls and Patients with Achalasia, Gastroenterology, Vol. 160, Issue 6, Supplement, S-459-S-460, Published in issue: May 2021
75. Patel K, Mei L, Lehal N, Sanvanson P, Kern K, Shaker R, Sa416 Fatigability of the Puborectalis Muscle by Repetitive Anal Contractions Against the Continence Muscles Resistance Exerciser Device, Gastroenterology, Vol. 160, Issue 6, Supplement, S-500-S-501, Published in issue: May, 2021
76. Edeani F, Kern M, Mei L, Yu E, Patel K, Sanvanson P, etc., Su188 Manometric Characteristics of Proximal Esophagus in 92 Asymptomatic Volunteers, Gastroenterology, Vol. 160, Issue 6, Supplement, S-641, Published in issue: May, 2021
77. Edeani F, Kern M, Mei L, Sanvanson P, Patel K, Kovacic K, etc., Su189 Effects of Bolus Volume on Upper Esophageal Sphincter Post-Deglutitive Contraction, Gastroenterology, Vol. 160, Issue 6, Supplement, S-641, Published in issue: May, 2021
78. Kern M, Sanvanson P, Mei L, Edeani F, Agrawal D, Patel K, etc., Su191 Effects of Swallowing Against Laryngeal Resistance (SALR) on Bolus Dynamics of the Esophageal Straited Muscle and Pharyngoesophageal Junction, Gastroenterology, Vol. 160, Issue 6, Supplement, S-642, Published in issue: May, 2021
79. Kern M, Sanvanson P, Mei L, Edeani F, Agrawal D, Patel K, etc., Su192 Correlation of the Striated Muscle Esophagus Pre-Peristaltic Liquid Bolus Dynamics with Pharyngeal Deglutitive Biomechanical Metrics, Gastroenterology, Vol. 160, Issue 6, Supplement, S-642-S-643, Published in issue: May, 2021
80. Kovacic K, Kern M, Mei L, Sancvanson P, Patel K, Lehal N, etc., Su201 Bolus Effect on Contractile Segment Impedance in Healthy Subjects, Gastroenterology, Vol. 160, Issue 6, supplement, S-646, Published in issues: May, 2021
81. Kovacic K, Kern M, Sanvanson P, Mei L, Edeani F, Shaker R, 266: General Anesthesia Using Sevoflurane, Alfentanil and Propofol Prior to Manometry Does Not Result in Abnormal Findings in Children Without Dysphagia, Gastroenterology Vol. 162Issue 7SupplementS-59Published in issue: May, 2022
82. Mei L, Edeani F, Yu E, Sanvanson P, Kern M, Shaker R, 1081: Further Characterization of Isolated Striated Esophagus Contraction as a Use Fortifying Mechanism Against Pharyngeal Reflux, Gastroenterology, Vol. 162, Issue 7, Supplement, S-251, Published in issue: May, 2022
83. Shaker R, Kern M, Edeani F, Mei L, Yu E, Sanvanson P, Sa1209: TEMPORO-SPATIAL MAPPING OF STRIATED ESOPHAGUS DEGLUTITIVE MOTOR FUNCTION, Gastroenterology, Vol. 162, Issue 7, Supplement, S-348, Published in issue: May, 2022
84. Edeani F, Kern M, Sanvanson P, Mei L, Yu E, Shaker R, Sa1213: Further Characterization of Striated Muscle Esophagus Contractile Function in Health and Disease, Gastroenterology, Vol. 162, Issue 7, Supplement, S-349–S-350, Published in issue: May, 2022
85. Kern M, Edeani F, Sanvanson P, Mei L, Shaker R, Su1240: Assessment of Bolus Injection Length (BIL): A Measure of Striated Esophageal Flow Dynamics by Mano-Impedance Compared to Video-Fluoroscopic Techniques, Gastroenterology, Vol. 162, Issue 7, Supplement, S-555–S-556, Published in issue: May, 2022
86. Kern M, Edeani F, Sanvanson P, Mei L, Shaker R, Su1243: Correlation of Striated Esophageal Flow Dynamics and Contractile Vigor: Difference Between Healthy Individuals and Patients, Gastroenterology, Vol. 162, Issue 7, Supplement, S-557, Published in issue: May, 2022
87. Kern M, Edeani F, Sanvanson P, Mei L, Shaker R, Su1244: The Effect of Aging on the Interaction Between Striated Esophageal Flow Dynamics and Contractile Vigor, Gastroenterology, Vol. 162, Issue 7, Supplement, S-557–S-558, Published in issue: May, 2022
88. Sanvanson P, Li Z, Medda B, Mei L, Shaker R, Mo1418: Impact of Vagotomy on Somatosensory Functional Networks in Rats Exposed to Esophageal ACID Infusion: An FCMRI Study, Gastroenterology, Vol. 162, Issue 7, Supplement, S-764, Published in issue: May, 2022
89. Yu E, Mehdi M, Mei L, Sanvanson P, Kern M, Shaker R, Tu1140: Reflux Associated Impedance Change in the Proximal Esophagus is not Accompanied by Changes in Contractility, Gastroenterology, Vol. 162, Issue 7, Supplement, S-899, Published in issue: May, 2022
90. Patel K, Mei L, Lehal N, Yu E, Kern M, Sanvanson P, etc., Su193 Effect of Respiration Pattern on Esophageal Motility Recorded by High Resolution Impedance Manometry, Gastroenterology, Vol. 160, Issue 6, Supplement, S-643, Published in issue: May, 2022
91. Mei, L; Yu, ES; Edeani, FO; Kern, M; Sanvanson, P; Shaker, R. Patients with Laryngo-Pharyngeal Reflux Demonstrate Impaired Striated Esophageal Response During Slow Simulated Acid Reflux Events and the Following Refluxate Dwell Periods. Gastroenterology 164 (6) S-821, May 2023.
92. Kern, M; Edeani, FO; Sanvanson, P; Mei, L; Shaker, R. The Effect of Aging on the Interaction Between Striated Esophageal Peristaltic Velocity, Contractile Vigor and Flow Dynamics. Gastroenterology, 164 (6) S-828, May 2023.
93. Kovacic, K; Kern, M; Sanvanson, P; Mei, L; Edeani, FO; Shaker, R. Substantial Number of Children with Esophageal Dysmotility are Erroneously Given Diagnosis of Normal Motility Per Chicago Classification. Gastroenterology, 164 (6) S-31, May 2023.
94. Hassan, H; Shaker, R; Yu, ES; Kern, M; Edeani, FO; Sanvanson, P; Mei, L. Acute Esophageal Acid Exposure Sensitizes The Upper Esophageal Sphincter Relaxation Response to Esophageal Air Distension. Gastroenterology, 164 (6) S-1024-S-1025, May 2023.
95. Edeani, FO; Shaker, R; Sanvanson, P; Mei, L; Hassan, H; Yu, ES; Kern, M. Patients with Diagnosis of Ineffective Esophageal Motility (IEM) Disorders Exhibit Abnormalities of Various Aspects of Striated Esophageal Motor Function. Gastroenterology, 164 (6) S-816, May 2023.
96. Yu, ES; Sanvnason, P; Mehdi, M; Patel, K; Kern, M; Edeani, FO; Shaker, R; Mei, L. Patients with Laryngopharyngeal Complications of Reflux Disease (LPR) Exhibit Impaired UES Response to Simulated Ultra-Slow Reflux Events. Gastroenterology, 164 (6) S-568, May 2023.
97. Yu, ES; Sanvanson, P; Mei, L; Edeani, FO; Hassan, H; Wells, M; Kern, M; Shaker, R. Feasibility and Safety of Concurrent Intragastric Pressure Measurements and Endoscopic Visualization of LES/GEJ Opening. Gastroenterology, 164 (6) S-1023-S-1024, May 2023.
98. Kerschner, A; Hassan, H; Edeani, FO; Mei, L; Kern, M; Sanvanson, P; Shaker, R; Yu, ES. Parkinson's Disease is Associated with Decreased Striated Esophagus Contractility Potentially Contributing to Development of Dysphagia. Gastroenterology, 164 (6) S-818-S-819, May 2023.
99. Mei, L; Hassan, H; Yu, Elliot; Kern, M; Weng, P; Edeani, FO; Sanvanson, P; Shaker, R. Fatigue Characteristics of Continence Muscles in Fecal Incontinent Patients. Gastroenterology, 166 (5) S-1384, May 2024.