CURRICULUM VITAE
Ling Mei MD
Ling Mei MD
Associate Professor
Department of Medicine
Division of Gastroenterology
Department of Medicine
Division of Gastroenterology
OFFICE ADDRESS: |
Hub for Collaborative Medicine |
8701 Watertown Plank Road |
Milwaukee, WI 53226 |
EDUCATION: |
07/1998 M.D., Shanghai Medical University, Shanghai, China |
07/2001 M.S., Fu Dan University, Shanghai, China |
06/2004 MPH, University of California, Los Angeles, Los Angeles, CA |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
07/1997 - 07/1998 Intern, Hua Shan Hospital, Shanghai Medical University, Shanghai, China |
09/1998 - 07/2001 Residency, Internal Medicine, Hua Shan Hospital, Medical Center of Fu Dan University, Shanghai, China |
11/2004 - 09/2006 Post Doctoral Research, Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, CA |
09/2009 - 08/2012 Resident, Medicine, Internal Medicine, New York Downtown Hospital, New York, NY |
08/2012 - 08/2015 Fellow, Medicine, Gastroenterology & Hepatology, Medical College of Wisconsin, Milwaukee, WI |
FACULTY APPOINTMENTS: |
09/2015 - Present Assistant Professor, Medicine, Gastroenterology & Hepatology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Wauwatosa, WI 53226 |
09/2015 - Present Faculty, Gastroenterology, Clement J. Zablocki VA Medical Center, 5000 W. National Ave, Milwaukee, WI 53214 |
HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS: |
09/2015 - Present Director, GI Motility Lab, Gastroenterology & Hepatology, Clement J. Zablocki VA Medical Center, Milwaukee, WI |
09/2020 - Present Associate Director, GI Motility Lab, Medicine, Gastroenterology & Hepatology, Medical College of Wisconsin, Milwaukee, WI |
HOSPITAL STAFF PRIVILEGES: |
09/2015 - Present Staff Physician, Medicine, Gastroenterology & Hepatology, Froedtert Hospital, 9200 W. Wisconsin Ave., Milwaukee, WI 53226 |
09/2015 - Present Staff Physician, Froedtert Surgery Center, Milwaukee, WI |
09/2015 - Present Staff Physician, Gastroenterology, Clement J Zablocki VA Medical Center, 5000 W. National Ave., Milwaukee, WI 53214 |
SPECIALTY BOARDS AND CERTIFICATION: |
Board Certified | Issue Date | Expiration |
Internal Medicine | 08/2012 | 08/2022 |
Gastroenterology | 11/2015 | 11/2025 |
Certificates | Issued By | Issue Date | Expiration |
Educational Commission for Foreign Medical Graduate | 10/2008 | None | |
AWARDS AND HONORS: |
2006 Genetic Analysis Workshop 15 Scholarship |
2016 - 2018 Certificate of Recognition for Scientific Accomplishments, AGA |
2017 Department of Medicine Research Retreat Award, Early Career Faculty - Basic or Translational Research, Froedtert and the Medical College of Wisconsin |
2018 Champion of Precision Medicine, Dept. of GI and Hep, Medical College of Wisconsin |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
2015 - Present American Gastroenterological Association (Member) |
2015 - Present Society of Dysphagia (Member) |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Journal Review |
2016 - Present Dysphagia |
2018 - Present Plos One-Digestive System |
2019 - Present Gastroenterology |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2015 - Present Member, Interview Committee Research and Clinical Fellowship Program, Medical College of Wisconsin |
2015 - Present Member, Clinical Competency Committee of Gastroenterology Fellowship, Medical College of Wisconsin |
2018 - 2020 Member, Precision Medicine Program, Medical College of Wisconsin |
2019 - Present Member, Committee for Diversity and Inclusion, Department of Medicine, Medical College of Wisconsin |
2021 Poster Judge, Department of Medicine, Research Retreat |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
Local |
Functional Bowel Disorders, DDW Review, Milwaukee, WI, 10/2016 |
Functional Anorectal Disorders, State of The Gut, Milwaukee, WI, 10/2017 |
Anorectal Disorder, State of The Gut, Milwaukee, WI, 10/2018 |
New Therapies in IBS, State of The Gut, Milwaukee, WI, 10/2019 |
Dietary Fiber in Gastrointestinal Health and Disease, Gastroenterology APP Monthly Meeting, Medical College of Wisconsin, Milwaukee, WI, 07/19/2021 |
Mei L, Siddique D, Motility, Research Seminar and Clinical Case Conference in Gastroenterology, Medical College of Wisconsin, Milwaukee, WI, 09/27/2021 |
Mei. L, Van Huis. A, Motility, Research Seminar and Clinical Case Conference in Gastroenterology, Medical College of Wisconsin, 03/21/2022 |
National |
Familial Expression of Anti-Escherichia Coli Outer Membrane Porin C (OmpC) in Relatives of Patients with Crhohn's Disease, American Gastroenterological Association, Chicago, IL, 05/2005 |
Genetic Variation in BTLA is Strongly Associated with Crohn's Disease, American Gastroenterological Association, San Diego, CA, 05/2008 |
Characterization of Impedance Signature of Pharyngo-UES Bolus Transit: A Comparative Study with Fluoroscopy, Digestive Disease Week, San Diego, CA, 05/2016 |
Effect of Aging on UES Pressure Response to Slow and Ultra-slow Simulated Reflux Events: Not all is Lost with Aging, Digestive Disease Week, Chicago, IL, 03/2017 |
Contractile Segment Impedance (CSI)During High-resolution Impedance Manometry Highly Correlates with Intraluminal Baseline Impedance (BI), and is Inversely Related to Esophageal Acid Exposure, Digestive Disease Week, Washington DC, 06/2018 |
Live demonstration of anorectal manometry and esophageal manometry, American Neurogastroenterology and Motility Society Conference, Milwaukee, WI, 07/27/2018 - 07/29/2018 |
Isolated sub-UES striated esophageal peristalsis in response to slow simulated reflux events; effect of age and chemical composition, DDW, Virtual, 2021 |
Mei L, FURTHER CHARACTERIZATION OF ISOLATED STRIATED ESOPHAGUS CONTRACTION AS A UES FORTIFYING MECHANISM AGAINST PHARYNGEAL REFLUX, Digestive Disease Week, San Diego, CA, 05/21/2022 - 05/24/2022 |
Esophageal Imaging/Research on Reflexes between Esophagus and UES: Current Updates and Future Directions, 3rd WDS (World Dysphagia Summit), San Francisco, CA, 03/13/2023 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
Regional |
Mei L, Dua A, Kern M, Gao S, Edeani F, Dua K, Wilson A, Sanvanson P, Jadcherla S, Shaker R, Effect of aging on UES pressure response to slow and ultra-slow simulated reflux events: Not all is lost with aging, To be presented as a poster at Digestive Diseases Week 2017, Chicago, IL, 05/06/2017 - 05/09/2017 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
2015 - Present Department IRB reviewer |
2018 - 2020 Member, Precision Medicine Program, Department of Medicine, Medical College of Wisconsin |
2019 - Present Member, Diversity and Inclusion, Medical College of Wisconsin |
2021 Poster judge, Research Retreat, Department of Medicine, Medical College of Wisconsin |
Hospital |
2015 - Present Clinical Competency Committee Member |
MEDICAL COLLEGE TEACHING ACTIVITIES: |
Medical Student Education |
10/2015 - Present Clinical Apprenticeship and Preceptor for Medical student M2/M3 (half day clinic per week) |
Resident and Fellow Education |
11/13/2019 Gastric Motor Disorder, Fellows Lecture, and Board Review |
12/2019 Academic Half Day Lecture: Functional GI Disorders |
02/2020 BST Mode Session on Gastroenterology |
05/04/2020 Fatigability of External Anal Sphincter Muscles During Various Exercise Methods Using a Novel Strength Training Resistance Exercise Device, Monday Night Gastroenterology Conference |
07/08/2020 Anorectal Manometry, Fellows Lecture, and Review Board |
EXTRAMURAL TEACHING: |
Medical Student Education |
03/2001 - 05/2001 Hua Shan Hospital, Teaching Assistant Letured interns on the diagnosis and treatment of common digestive diseases. |
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Medical Students |
Medical College of Wisconsin, 10/2015 - Present Clinical Apprenticeship |
Clinical/Research Fellows |
Francis Edeani, MD, Medical College of Wisconsin, 2016 - 2018 T32 Research Fellow, Resulted in accepted abstracts and manuscript (peer-reviewed publication #38, #42, #43), presentation at a national meeting, and faculty position at Medical College of Wisconsin |
Shaina Lynch, MD, Medical College of Wisconsin, 06/2017 - 06/2019 T32 Research Fellow, Resulted in accepted abstracts, presentation at a national meeting |
Karlo Kovacic, Medical College of Wisconsin, 2017 - Present T32 Research Fellow, Resulted in accepted abstracts, presentation at a national meeting, and faculty position at Children's Wisconsin |
Krupa Patel, MD, Medical College of Wisconsin, 06/2019 - Present T32 Research Fellow, Resulted in accepted abstracts and manuscript (peer-reviewed publication #42), presentation at a national meeting |
Elliot Yu, MD, Medical College of Wisconsin, 07/2020 - Present T32 Research Fellow, Resulted in accepted abstracts, presentation at a national meeting |
Residents |
Arshish Dua, Medical College of Wisconsin, 2015 - 2016 GI Research Rotation, Resulted in accepted abstracts and manuscript (peer-reviewed publication #35, #38), presentation at a national meeting |
Kathan Chintamaneni, Medical College of Wisconsin, 2016, Accepted Abstract |
Ghavesh Katbamna, Medical College of Wisconsin, 2020 GI Research Rotation |
Clinical Staff |
Benjamin Liu, Medical College of Wisconsin, 2021 - 2022 M4 Clinical Advisor |
PROGRAMMATIC DEVELOPMENTS: |
Research Programs |
2015 - Present Mentor T32 trainees in the GI motility lab on the principles of esophageal and anorectal motility in normal individuals and on clinical motility disorders. |
Clinical Programs |
2015 - Present I help to re-establish and update the GI motility lab since I joined the faculty in VA. |
LANGUAGE: |
English, Chinese |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Lan Rong, Ling Mei, Wei Lu. Immunologic research of millimeter wave radiation on rats hepatoma. The 1st National Conference on the medical appliance of Millimeter Wave, 1999, 128-31 |
2. Rong L, Lu W, Sun DY, Mei L, Zhou BD. Effects of 33.6 GHz millimeter wave radiation on immune function of rats with DEN-induced hepatoma. Chin J Phys Med Rehabil, 2001; 23(1):29-31 |
3. Mei L, Lu W. Effects of Somatostatin on the diagnosis and treatment of gastrointestinal cancer. Foreign Medicine (volume of digestive disease), 2001, 21(2):90-4 |
4. Hu R, Zhai QW, He WJ, Mei L, Liu WY. Pegylation and its effect on the bioactivities and immunoreactivity of ricin. Intern J Biochem & Cell Biol, 2002, 34, 396-402 |
5. Jiang YB, Rong L, Mei L, Zhou BD, Lu W. Effect of millimeter wave radiation on apoptosis of human hepatoma cell. Chin J Digestion, 2002, 22(2): 103-6 |
6. Lu W, Zhou BD, Mei L, Sun D, Rong L. Expression of proliferating cell nuclear antigen, CDK4 and P16 in rat hepatocellular carcinoma by millimeter wave radiation. Chin J Digestion, 2002, 22(6): 357-60 |
7. Mei, L., Targan, S.R., Landers, C., Dutridge, D., Ippoloti, A., Vasiliauskas, E.A., Papadakis, K.A., Fleshner, P., Rotter, J.I., Yang, H.: Familial expression of anti-Escherichia coli outer membrane porin C (OmpC) in relatives of patients with Crohn’s disease, Gastroenterology, 130:1078-1085, April, 2006. |
8. Schluender SJ, Mei L, Yang H, Fleshner PR. Can a meta-analysis answer the question: is mucosectomy and handsewn or double-stapled anastomosis better in ileal pouch-anal anastomosis? Am Surg. 2006 Oct;72(10):912-6. |
9. Wilcox MA, Li Z, Tapper W, Browning S, Curtin K, Ding J, Ding Y, Gagnon F, He Q, Kuo TY, Li M, Matthew G, Mei L, Rao S, Shaw J, Wei Z, Yu Z, Zhang W, Zheng T, Zhu G. Genetic association with rheumatoid arthritis-Genetic Analysis Workshop 15: summary of contributions from Group 2. Genet Epidemiol. 2007;31 Suppl 1:S12-21. |
10. Papadakis, KA, Yang,H, Ippoliti, A, Mei, L, Elson, CO, Hershberg RM, Vasiliauskas, EA, Fleshner, PR, Abreu, MT, Taylor, K, Landers, CJ, Rotter, JI, Targan, SR. Anti-Flagellin (Cbir1) phenotypic and genetic Crohn’s disease association. Inflamm Bowel Dis. 2007 Jan 26;13(5):524-530 |
11. Devlin, S.M., Yang, H., Ippoliti, A., Taylor, K.D., Landers, C.J., Su, XW, Abreu, M.T., Papadakis, K., Vasiliauskas, E, Melmed, G., Fleshner, P., Mei, L., Rotter, J.I., Targan, S.R. NOD2/CARD15 variants are significantly associated with sero-reactivity to microbial antigens in patients with Crohn’s disease and their unaffected relatives. Gastroenterology. 2007 Feb;132(2):576-86. |
12. Su, X., Lee, L., Li, X., Lu, J., Hu, Y., Zhan, S., Cao, W., Mei, L., Tang, Y., Wang, D., Krauss, R., Rotter, J.I., Yang, H.: Association between angiotensin I receptor genes and blood pressure response to an ACE inhibitor. Circulation. 2007 Feb 13;115(6):725-32. |
13. Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.
Nat Genet. 2007 May;39 (5):596-604.
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14. Fleshner,P.,Ippoliti, A., Dubinsky, M., Ognibene, S., Vasiliauskas, E., Chelly, M., Mei, L., Papadakis, KA., Landers, C., Targan,S.. A prospective multivariate analysis of perioperative clinical factors associated with pouchitis after Ileal Pouch-Anal Anastomosis. Clin Gastroenterol Hepatol. 2007 Aug;5(8):952-8 |
15. Picornell Y, Mei L, Taylor K, Yang H, Targan SR, Rotter JI. TNFSF15 is an ethnic-specific IBD gene. Inflamm Bowel Dis. 2007 Nov;13(11):1333-8. PMCID: PMC2552994 |
16. Schluender SJ, Ippoliti A, Dubinsky M, Vasiliauskas EA, Papadakis KA, Mei L, Targan SR, Fleshner PR. Does infliximab influence surgical morbidity of ileal pouch-anal anastomosis in patients with ulcerative colitis? Dis Colon Rectum. 2007 Nov;50(11): 1747-53 |
17. Mei L., Li X., Yang K., Cui J., Fang B., Guo X., Rotter JI. Gene-gene interaction and gene-smoking interaction in Rheumatoid Arthritis. BMC Proc. 2007 Dec, 1(suppl 1):S17 |
18. Dubinsky, M., Kugathsan, S., Mei, L., Picornell, Y., Nebel, J., Wrobel, I., Quiros, A., Silber, G., Wahbeh, G., Katzir, L., Vasiliauskas, E., Bahar, R., Otley, A., Mack, D., Evans, J., Rosh, J., Oliva, H.M., Leleiko, N., Crandall, W., Langton, C., Taylor, K., Targan, S., Rotter, J., Markowitz, J., Hyams, J. for the Western Regional Pediatric IBD Research Alliance, Pediatric IBD Collaborative Research Group and the Wisconsin Pediatric IBD Alliance: Increased immune reactivity predicts aggressive complicating Crohn’s disease in children, Clinical Gastroenterology and Hepatology, 2008, 6(10):1105-11 |
19. Fleshner P, Ippoliti A, Dubinsky M, Vasiliauskas E, Mei L, Papadakis KA, Rotter JI, Landers C, Targan S. Both preoperative perinuclear antineutrophil cytoplasmic antibody and anti-CBir1 expression in ulcerative colitis patients influence pouchitis development after ileal pouch-anal anastomosis. Clin Gastroenterol Hepatol. 2008 May;6(5):561-8. PMCID: PMC2742560 |
20. Taylor KD, Targan SR, Mei L, Ippoliti AF, McGovern D, Mengesha E, King L, Rotter JI. IL23R haplotypes provide a large population attributable risk for Crohn's disease. Inflamm Bowel Dis. 2008 Sep;14(9):1185-91. PMCID: PMC2574614 |
21. Saruta, M., Targan, S.R., Mei, L., Ippoliti, A.F., Taylor, K.D., Rotter, J.I.: High frequency haplotypes in the X-chromosome locus TLR8 are associated with both CD and UC in females, Inflammatory Bowel Diseases, 2009;15(3):321-7. |
22. Takedatsu, H., Taylor, K.D., Mei, L., McGovern, D.P., Landers, C.J., Gonsky, R., Cong, Y., Vasiliauskas, E.A., Ippoliti, A., Elson, C.O., Rotter, J.I., Targan, S.R.: Linkage of CD-related serological phenotypes: NFKB1 haplotypes are associated with anti-CBir1 and ASCA, and show reduced NF-B activation, Gut, 58:60-67, 2009 |
23. Mundwiler ML, Mei L, Landers CJ, Reveille JD, Targan S, Weisman MH. Inflammatory bowel disease serologies in ankylosing spondylitis patients: a pilot study. Arthritis Res Ther. 2009;11(6):R177. PMCID: PMC3003540 |
24. Markowitz J, Kugathasan S, Dubinsky M, Mei L, Crandall W, Leleiko N, Oliva-Hemker M, Rosh J, Evans J, Mack D, Otley A, Pfefferkorn M, Bahar R, Vasiliauskas E, Wahbeh G, Silber G, Quiros JA, Wrobel I, Nebel J, Landers C, Picornell Y, Targan S, Lerer T, Hyams J. Age of diagnosis influences serologic responses in children with Crohn's disease: A possible clue to etiology? Inflamm Bowel Dis. 2009 May;15(5):714-9. |
25. Michelsen, K.S., Thomas, L.S., Taylor, K.D., Yu, Q.T., Mei, L., Landers, C.J., Derkowski, C., McGovern, D.P., Rotter, J.I., Targan, S.R.: IBD-associated TL1a (TNFSF15) haplotypes determine increased expression of TL1A protein, PLoS One. 2009;4(3):e4719. |
26. McGovern, D.P.B., Taylor, K.D., Landers, C., Derkowski, C., Dutridge, D., Dubinsky, M., Ippoliti, A., Vasiliauskas, E., Mei, L., Mengesha, E., King, L., Pressman, S., Targan, S.R., Rotter, J.I.: MAGI2 genetic variation and inflammatory bowel disease (IBD), Inflammatory Bowel Diseases, 2009,15(1):75-83. |
27. McGovern, D.P.B., Rotter, J.I., Mei, L., Haritunians, T., Landers, C., Derkowski, C., Dutridge, D., Dubinsky, M., Ippoliti, A., Vasiliauskas, E., Mengesha, E., King, L., Pressman, S., Targan, S.R., Taylor, K.D.: Genetic epistasis of IL23/IL17 pathway genes in Crohn’s disease, Inflammatory Bowel Disease, 2009 Jun;15(6):883-9. |
28. Hollenbach JA, Ladner MB, Saeteurn K, Taylor KD, Mei L, Haritunians T, McGovern DP, Erlich HA, Rotter JI, Trachtenberg EA. Susceptibility to Crohn's disease is mediated by KIR2DL2/KIR2DL3 heterozygosity and the HLA-C ligand. Immunogenetics. 2009 Oct;61(10):663-71. PMCID: PMC2813946 |
29. Li X, Mei L, Yang K, Rotter JI, Guo X. Identifying association under a previous linkage peak on chromosome 16 for body mass index using cross-sectional and longitudinal data of the Framingham Heart Study. BMC Proc. 2009 Dec 15;3 Suppl 7(Suppl 7):S101. PMCID: PMC2795872 |
30. Dubinsky MC, Mei L, Friedman M, Dhere T, Haritunians T, Hakonarson H, Kim C, Glessner J, Targan SR, McGovern DP, Taylor KD, Rotter JI. Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2010 Aug;16(8):1357-66. PMCID: PMC2889173 |
31. Ippoliti A, Devlin S, Mei L, Yang H, Papadakis KA, Vasiliauskas EA, McGovern DP, Abreu MT, Melmed G, Shaye O, Enayati P, Chen G, Choi J, Taylor K, Landers CJ, Rotter JI, Targan SR. Combination of innate and adaptive immune alterations increased the likelihood of fibrostenosis in Crohn's disease. Inflamm Bowel Dis. 2010 Aug;16(8):1279-85. PMCID: PMC3875376 |
32. Shih DQ, Nguyen M, Zheng L, Ibanez P, Mei L, Kwan LY, Bradford K, Ting C, Targan SR, Vasiliauskas EA. Split-dose administration of thiopurine drugs: a novel and effective strategy for managing preferential 6-MMP metabolism. Aliment Pharmacol Ther. 2012 Sep;36(5):449-58. |
33. Jiao H, Mei L, Sharma T, Kern M, Sanvanson P, Shaker R. A human model of restricted upper esophageal sphincter opening and its pharyngeal and UES deglutitive pressure phenomena. Am J Physiol Gastrointest Liver Physiol. 2016 Jul 01;311(1):G84-90. PMCID: PMC4967170 |
34. Jiao H, Mei L, Liang C, Dai Y, Fu Z, Wu L, Sanvanson P, Shaker R. Upper esophageal sphincter augmentation reduces pharyngeal reflux in nasogastric tube-fed patients. 2017 Oct 8. doi: 10.1002/lary.26895. |
35. Mei L, Jiao H, Sharma T, Dua A, Sanvanson P, Jadcherla SR, Shaker R. Comparative effect of the sites of anterior cervical pressure on the geometry of the upper esophageal sphincter high-pressure zone. Laryngoscope. 2017 Nov;127(11):2466-2474. PMCID: PMC5654682 |
36. Balasubramanian G, Sharma T, Kern M, Mei L, Sanvanson P, Shaker R. Characterization of pharyngeal peristaltic pressure variability during volitional swallowing in healthy individuals. Neurogastroenterol Motil. 2017 Nov;29(11). PMCID: PMC6757324 |
37. Xu X, Li C, Gao X, Xia K, Guo H, Li Y, Hao Z, Zhang L, Gao D, Xu C, Xu H, Xiong Z, Qiu Z, Mei L, Xie X, Ruan K, Hu R, Excessive UBE3A dosage impairs retinoic acid signaling and synaptic plasticity in autism spectrum disorders, Cell Res. 2018 Jan;28(1):48-68, PMID: 29076503 |
38. Mei L, Dua A, Kern M, Gao S, Edeani F, Dua K, Wilson A, Lynch S, Sanvanson P, Shaker R. Older Age Reduces Upper Esophageal Sphincter and Esophageal Body Responses to Simulated Slow and Ultraslow Reflux Events and Post-Reflux Residue. Gastroenterology. 2018 Sep;155(3):760-770.e1. PMCID: PMC6120791 |
39. Sanvanson P, Li Z, Mei L, Kounev V, Kern M, Ward BD, Medda B, Shaker R. Interplay of spinal and vagal pathways on esophageal acid-related anterior cingulate cortex functional networks in rats. Am J Physiol Gastrointest Liver Physiol. 2019 May 01;316(5):G615-G622. PMCID: PMC6580238 |
40. Wang L, Echeveste CE, Yu J, Huang Y, Lechner J, Mei L, Sanvanson P, Yearsley M, Wang C, Stoner G. Can Natural Products Suppress Resistant Helicobacter pylori to Fight Against Gastric Diseases in Humans? eFood 2020 Feb;1(1):53-60 PMID: 34308385 |
41. Boschuetz N, Cheng S, Mei L, Loy VM. Changes in Alcohol Use Patterns in the United States During COVID-19 Pandemic. WMJ. 2020 Sep;119(3):171-176. |
42. Mei L, Patel K, Lehal N, Kern MK, Benjamin A, Sanvanson P, Shaker R. Fatigability of the external anal sphincter muscles using a novel strength training resistance exercise device. Am J Physiol Gastrointest Liver Physiol. 2021 Apr 01;320(4):G609-G616. PMCID: PMC8238165 |
43. Patel K, Mei L, Yu E, Kern M, Lehal N, Edeani F, Sanvanson P, Davidson ERW, Shaker R. Differences in fatigability of muscles involved in fecal continence: Potential clinical ramifications. Physiol Rep. 2021 Dec;9(24):e15144. PMCID: PMC8685596 |
44. Edeani F. Kern, M. Ulualp, K. Kovacic, K. Sanvanson, P. Mei, L. Shaker, R. Variables influencing manometric parameters of deglutitive and non-deglutitive upper esophageal sphincter: A study of 89 asymptomatic participants, Neurogastroenterol Motil. 2022 Feb;34(2):e14175, PMID: 34431179 |
45. Edeani F, Sanvanson P, Mei L, Agrawal D, Kern M, Kovacic K, Shaker R. Effect of inter-swallow interval on striated esophagus peristalsis; a comparative study with smooth muscle esophagus. Neurogastroenterol Motil. 2023 Aug;35(8):e14608. PMCID: PMC10789016 |
Books, Chapters, and Reviews |
1. Ling Mei, Patrick Sanvanson (2017). UES restrictive disorders. In Barden, E, Shaker, R (Ed), Gastrointestinal Motility Disorders. A point of care clinical guide. (pp79-90.)Springer International Publishing |
Abstracts |
1. Mei L, Landers C, Dutridge D, Ippoliti A, Vasiliauskas EA, Papadakis KA, Fleshner P, Targan SR, Rotter JI, Yang H. Familial expression of anti-Escherichia coli outermembrane porin C (OmpC) in relatives of patients with Crohn’s disease, Gastroenterology,128(S2): A2, April, 2005. Presented (oral) to the annual meeting of the American
Gastroenterological Association, Chicago, May 15-18, 2005. |
2. Mei L, Picornell Y, Gregory F, Mera R, Wang D, Dutridge D, Rotter, JI, Torres EA, Yang H. Association between ancestry proportion and inflammatory bowel disease in Puerto Ricans. Gastroenterology, 130(Suppl 2):A587, April, 2006. Presented to the annual meeting of the American Gastroenterological Association, Los Angeles, May 21-24, 2006. |
3. Mei L, Torres EA, Picornell Y, Su X, Gregory F, Mera R, Nieves PJ, Dutridge D, Taylor K, Yang H, Rotter JI: CARD8 is associated with Crohn’s disease in the Puerto Rico population. American Journal of Human Genetics, 2006. Presented to the annual meeting of the American Society of Human Genetics, New Orleans, October 9-14, 2006. |
4. Mei L, Su X, Ippoliti AF, Taylor KD, Targan S, Rotter JI: Association between IL17A and IL17RA genes and inflammatory bowel diseases (IBD). Gastroenterology, 2007. Presented to the annual meeting of the American Gastroenterological Association, Washington,
DC, May 19-24, 2007. |
5. Mei L, Taylor KD, McGovern D, Picornell Y, Su X, Landers CJ, Targan SR, Rotter,JI. Variants in genes related to innate (NOD2, TLR5) and adaptive (TNFSF15/TL1A)immune pathways combine to increase the magnitude of anti-OMPC expression in Jewish CD subjects. Gastroenterology, 2008. Presented to the annual meeting of the American Gastroenterological Association, San Diego, May 17-22, 2008. |
6. Mei L, Taylor KD, Landers CJ, McGovern D, Targan SR, Rotter JI. Genetic variation in BTLA is strongly associated with Crohn’s disease. Gastroenterology, 2008. Presented (oral) to the annual meeting of the American Gastroenterological Association, San
Diego, May 17-22, 2008. |
7. Mei L, Taylor KD, McGovern D, Targan S, Rotter JI. Association between IL17RD gene and Crohn’s disease and gene-gene interaction in the IL23-IL17 pathway. American Journal of Human Genetics: A416, 2008. Presented to the annual meeting of the American Society of Human Genetics, Philadelphia, November 11-15, 2008.
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8. Mei L, Vendrell R, Cruz A, Ortiz Z, Rabell N, Rivera M, Rivera C, Salas M, Dutridge D, Landers C, Targan S, Rotter JI, Taylor KD, Torres EA. Childhood hygiene shifts serological profiles in adult CD. Gastroenterology, 2009. Presented to the annual meeting of the American Gastroenterological Association, Chicago, May 30-June 3, 2009. |
9. Sharma T, Babaei A, DeMara-Hoth M, Mei L, Sanvanson PP, Kern M, Jiao H, Shaker R. Effect of Neck Positions, Bolus Volume and Body Posture on High Resolution Pharyngo- UES Manometry. May 2013 Gastroenterology, Vol. 144, Issue 5, S-785 |
10. Sanvanson PP, Kounev V, Mei L, Li R, Hyde JS, Medda BK, Shaker R. Esophageal Acid Induced Brain Functional Connectivity Changes Are Vagally Mediated. May 2013 Gastroenterology, Vol. 144, Issue 5, S-562–S-563 |
11. Fang, T., Mei, L., Dua, KS. Correlation of Degree of Dysphagia with Endoscopic Ultrasound T-stage of Esophageal Cancer. Presented to DDW2013, Orlando, May 17-22, 2013 |
12. Mei L, Kounev V, Sanvanson PP, Li R, Li SJ, Medda BK, Shaker R. Effect of Vagotomy on Cortical FMRI Activity Induced by Esophageal Acid Stimulation in Rats: Further Validation of the Model. May 2013 Gastroenterology, Vol. 144, Issue 5, S-558 |
13. Mei L, Jiao H, Sharma T, Sanvanson P, Jadcherla SR, Shaker R. Effect of External Anterior Cervical Pressure Location on the UES High-Pressure Zone Is Site Specific. May 2014 Gastroenterology, Vol. 146, Issue 5, S-895–S-896 |
14. Babaei A, Jiao H, Mei L, Kern M, Shaker R. Correlation of Externally Applied Cricoid Pressure With Luminal Upper Esophageal Sphincter Pressure Augmentation; Effect of Posture and Technique. May 2014 Gastroenterology, Vol. 146, Issue 5, S-856 |
15. Mei L, Sanvanson P, Kounev V, Li R, Medda BK, Shaker R. Effect of Chronic Esophageal Acid Exposure and Acute Acid Re-Challenge on Functional Connectivity of Anterior Cingulate Cortex in Rats. May 2014 Gastroenterology, Vol. 146, Issue 5, S-846 |
16. Kern M, Babaei A, Siwiec RM, Samuel EA, Mei L, Sanvanson P, Shaker R. Differences in Amygdala Functional Connectivity Between Erosive (ERD) and Non-Erosive Reflux Disease (NERD) Patients During Esophageal Acid Exposure. May 2014 Gastroenterology, Vol. 146, Issue 5, S-844 |
17. Sanvanson P, Mei L, Kounev V, Li R, Hyde JS, Medda BK, Shaker R. Functional Connectivity of Somatosensory Cortex Is Enhanced by Acute Esophageal Acid Exposure in Rats. May 2014 Gastroenterology, Vol. 146, Issue 5, S-844–S-845 |
18. Sharma T, Mei L, Jiao H, Shaker R. Nadir UES Relaxation and Hypopharyngeal Intra Bolus Pressures Are More Sensitive to Consistency and Viscosity Challenge Than Pharyngeal Peristalsis Parameters Measured by High Resolution Manometry. May 2014 Gastroenterology, Vol. 146, Issue 5, S-78 |
19. Jiao H, Mei L, Babaei A, Sharma T, Sanvanson P, Kern M, Jadcherla SR, Shaker R. A Human Model of Restricted UES Opening and Its Characteristic Pharyngeal and UES Deglutitive Pressure Phenomena. May 2014 Gastroenterology, Vol. 146, Issue 5, S-77 |
20. Rage A, Seamon AR, Mohorek MR, Mei L, Massey BT. A Rapid Initial Lag Phase of Gastric Emptying Is Associated With a Greater Degree of Obesity and Weight Gain Over Time. April 2015 Gastroenterology, Vol. 148, Issue 4, S-669 |
21. Shaker R, Balasubramanian G, Babaei A, Manderle R, Mei L, Kern M. Effect of a Novel “Resistance Exercise Device” for Swallowing on Pharyngeal Peristalsis. April 2015 Gastroenterology, Vol. 148, Issue 4, S-168–S-169 |
22. Balasubramanian G, Kern M, Mei L, Maderle R, Babaei A, Shaker R. Variability of Pharyngeal Peristaltic Pressure Parameters Measured by High Resolution Manometry (HRM); A Study of Over 900 Pressure Signatures. April 2015 Gastroenterology, Vol. 148, Issue 4, S-167 |
23. Balasubramanian G, Kern M, Manderle R, Mei L, Sanvanson P, Babaei A, Shaker R. Dynamics of Pharyngeal Contraction During Vocalization, Cough and Swallowing Maneuvers Using High Resolution Manometry. April 2015 Gastroenterology, Vol. 148, Issue 4, S-895 |
24. Kern M, Balasubramanian G, Mei L, Manderle R, Babaei A, Shaker R. Inter-Rater Agreement for Analysis of Pharyngeal High Resolution Manometry Parameters. April 2015 Gastroenterology, Vol. 148, Issue 4, S-896 |
25. Mei L, Balasubramanian G, Manderle R, Kern M, Sanvanson P, Jiao H, Shaker R. Pharyngeal Bolus Transit in a Human Model of Restricted Swallowing; A Multi-Channel Intraluminal Impedance Study. April 2015 Gastroenterology, Vol. 148, Issue 4, S-895 |
26. Mei L, Sanvanson P, Balasubramanian G, Kern M, Wuerl A, Shaker R. Characterization of Impedance Signature of Pharyngo-UES Bolus Transit: A Comparative Study With Fluoroscopy. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S96. |
27. Kern M, Sanvanson P, Mei L, Wuerl A, Shaker R. Differences in Resting State Connectivity of the Homeostatic Interoceptive Network in Erosive as Well as Non-Erosive GERD Patients and Healthy Controls. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-107 - S-108 |
28. Hongmei J, Mei L, Liang C, Dai Y, Fu Z, Wu L, Sanvanson P, Shaker R. UES Assist Device Reduces the Aspiration Risk By Decreasing Trans-UES Reflux of Gastric Content in Long-Term Nasogastric Tube Fed Patients: A Combined pH-Multichannel Intraluminal Impedance Study. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-110 - S-111 |
29. Kern M, Balasubramanian G, Sanvanson P, Mei L, Wuerl A, Hyngstrom A, Shaker R. Augmenting the Training Effect of a Swallow Resistance Exercise Device (sRED): Lessons From Exercise Physiology. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-860 |
30. Kern M, Balasubramanian G, Sanvanson P, Mei L, Wuerl A, Shaker R. Biomechanical Evidence of UES Opening Muscle Fatigue Induced by Resistance to Deglutitive Hyo-Laryngeal Excursion. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-860 |
31. Kern, M. Balasubramanian G, Sanvanson P, Mei L, Wuerl A, Shaker R. Characterization of the Biomechanical Effects of Externally Applied Resistance to Deglutitive Hyo-Laryngeal Excursion. April 2016 Gastroenterology, Vol. 150, Issue 4, S-859 - S-860 |
32. Kern M, Balasubramanian G, Sanvanson P, Mei L, Wuerl A, Shaker R. Safety of Restricting the Deglutitive Hyo-Laryngeal Excursion for Overloading and Strength Training of Swallow Muscles. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-861 |
33. Sanvanson P, Sobin M, Balasubramanian G, Mei L, Wuerl A, Kern M, Shaker R. Effect of Repeated Swallows Against Resistance on Proximal Striated Muscle Segment of Esophagus in the Elderly. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-293 - S294 |
34. Gao S, Kern M, Balasubramanian G, Sanvanson P, Mei L, Hyngstrom A, Shaker R. Effect of Repeated Swallowing Against Laryngeal Resistance on the Deglutitive Trajectories of the Hyoid and Larynx; A Study of Post-contraction Relaxation Velocity. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-862 |
35. Sanvanson P, Li Z, Mei L, Kounev V, Medda BK, Ward BD, Kern M, Shaker R. A Novel Method for Characterizing Cerebral Response to Esophageal Acid Exposure by fMRI and fcMRI. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-527-S528 |
36. Sanvanson P, Li Z, Mei L, Kounev V, Medda BK, Ward BD, Kern M, Shaker R. Alterations of Thalamic Networks in Response to Esophageal Acid Infusion: A Functional Connectivity Study in Rats. April 2016 Gastroenterology, Vol. 150, Issue 4, Supplement 1, S-528 |
37. Mei L, Dua A, Kern M, Gao S, Edeani F, Dua K, Wilson A, Sanvanson P, Jadcherla S, Shaker R. Effect of aging on UES pressure response to slow and ultra-slow simulated reflux events: Not all is lost with aging. To be presented as a poster at Digestive Diseases Week 2017. |
38. Kern M, Balasubramanian G, Sanvanson P, Mei L, Agrawal D, Shaker R. Feasibility and testing of group HRM isocontour maps as a means to facilitate comparison across individuals and conditions: Development of a learning comparative "ManoBank." To be presented as a poster at Digestive Diseases Week 2017. |
39. Agrawal D, Kern M, Stevens S, Dulitz L, Dummer T, Monday A, Antinoja J, Wilson A, Balasubramanian G, Edeani F, Mei L, Sanvanson P, Shaker R. Strength training using a novel Swallow Resistance Exercise Device (sRED) improves oropharyngeal swallow function, deglutitive UES opening, and biomechanics in a heterogeneous group of dysphagic patients. To be presented as a poster at Digestive Diseases Week 2017. |
40. Sanvanson P, Mei L, Li Z, Kounev V, Medda B, Shaker R. Interplay of spinal and vagal pathways on the esophageal acid-related anterior cingulate cortex functional networks in rats. To be presented as a poster at Digestive Diseases Week 2017. |
41. Agrawal D, Kern M, Gao S, Wilson A, Edeani F, Mei L, Sanvanson P, Shaker R. Reversal of pharyngeal constrictor sarcopenia by resistance strength training exercise in the elderly. To be presented as a poster at Digestive Diseases Week 2017. |
42. Agrawal D, Kern M, Wilson A, Ulualp K, Li Z, Balasubramanian G, Edeani F, Mei L, Sanvanson P, Shaker R. Effect of a novel strength training exercise technique on pharyngeal phase of swallowing musculature in the elderly: A case for developing preventative swallow health maintenance exercise program in geriatric population. To be presented as a poster at Digestive Diseases Week 2017. |
43. Kern M, Sanvanson P, Li Z, Wilson A, Mei L, Shaker R. Comparison of brain function during normal swallow and swallow against resistance: The effect of effort. To be presented as a poster at Digestive Diseases Week 2017. |
44. Mei L, Sanvanson P, Li Z, Medda B, Shaker R. Chronic esophageal acid exposure modifies functional connectivity of anterior cingulate cortex during acute acid challenge in rats. To be presented as a poster at Digestive Diseases Week 2017. |
45. Mei L, Sanvanson P, Jiao H, Shaker R. Manometric characteristics of esophageal striated muscle contractility in a human model of restricted upper esophageal sphincter opening. To be presented as a poster at Digestive Diseases Week 2017. |
46. Edeani F, Ulualp K, Sanvanson P, Mei L, Agrawal D, Kern M, Wilson A, Dua A, Shaker R. Effect of experimental perturbation of pharyngeal phase of swallowing on esophageal motor function. To be presented as a poster at Digestive Diseases Week 2017. |
47. Kern M, Edeani FO, Lynch SM, Sanvanson P, Mei L, Crumb C, Shaker R. Spatial Intra-Luminal Pressure Gradient and Variance of Esophageal Pressure Magnitudes in Achalasia Sub-Types and Healthy Controls. May 2018. Gastroenterology, Vol. 154, Issue 6, S-738–S-739
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48. Edeani FO, Sobin M, Saeian S, Mei L, Kern M, Sanvanson P, Shaker R. Examining the Deglutitive Integrated Relaxation Pressure (IRP) of the Lower Esophageal Sphincter (LES) in 60 Healthy Asymptomatic Controls and 69 Achalasia Patients. May 2018. Gastroenterology, Vol. 154, Issue 6, S-739.
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49. Kern M, Edeani FO, Lynch SM, Sanvanson P, Mei L, Crumb C, Shaker R. Agglomerative Hierarchical Clustering of Esophageal Body Manometric Isocontour Data: Similartities and Differences Across Four Patient Groups and Healthy Subjects. May 2018 Gastroenterology, Vol. 154, Issue 6, S-971.
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50. Kern M, Edeani FO, Sanvanson P, Mei L, Lynch SM, Crumb C, Shaker R. An Esophageal “Manobank”: Feasibility and Testing of Group HRM Isocontour Pressure Maps of Centrality and Dispersion to Facilitate Comparison Across Individuals and Conditions. May 2018 Gastroenterology, Vol. 154, Issue 6, S-970–S-971.
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51. Edeani FO, Kern M, Sanvanson P, Mei L, Ulualp K, Crumb C, Cheng CY, Shaker R. Effects of Position, Age, Gender, and Number of Swallows on Multiple Rapid Swallow (MRS)-Induced Peristaltic Augmentation of the Distal Esophagus. May 2018 Gastroenterology, Vol. 154, Issue 6, S-739.
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52. Edeani FO, Kern M, Sobin M, Sanvanson P, Lynch SM, Mei L, Crumb C, Cheng CY, Shaker R. Effect of Aging on Deglutitive Lower Esophageal Sphincter Integrated Relaxation Pressure. May 2018 Gastroenterology, Vol. 154, Issue 6, S-966.
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53. Edeani FO, Ulualp K, Kern M, Kovacic K, Sanvanson P, Mei L, Shaker R. Manometric Parameters of Deglutitive upper Esophageal Sphincer Across Age Spectrum: A Study of 87 Healthy Participants. May 2018 Gastroenterology, Vol. 154, Issue 6, S-13.
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54. Kern M, Edeani FO, Lynch SM, Sanvanson P, Mei L, Crumb C, Shaker R. Machine Learning Techniques for Classifying High Resolution Manometric Isocontours. May 2018 Gastroenterology, Vol. 154, Issue
6, S-738.
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55. Shaker R, Edeani FO, Agrawal D, Mei L, Lynch SM, Wilson A, Crumb C, Sanvanson P. A Single Combined Manometry and Perfusion Catheter for Studying the Upper Esophageal Sphincter Competency: UES Stress Test Catheter. May 2018 Gastroenterology, Vol. 154, Issue 6, S-473–S-474.
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56. Edeani FO, Sanvanson P, Kovacic K, Lynch SM, Mei L, Crumb C, Kern M, Shaker R. Comparison Between the Effect of Swallow Interval on Striated and Smooth Muscle Esophagus Peristalsis. May 2018 Gastroenterology, Vol. 154, Issue 6, S-966.
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57. Kern M, Edeani FO, Lynch SM, Sanvanson P, Mei L, Crumb C, Shaker R. Ineffective Esophageal Motility Manometric Isocontour Analysis: Spatiotemporal Differences from Healthy Controls. May 2018
Gastroenterology, Vol. 154, Issue 6, S-971–S-972.
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58. Mei L. Babaei A. Contractile Segment Impedance (CSI) During High-Resolution Impedance Manometry Highly Correlates with Intraluminal Baseline Impedance (BI), and is Inversely Related to Esophageal Acid Exposure. May 2018 Gastro 154(6): S85 |
59. Mei L, Kern M, Edeani F, Wilson A, Sanvanson P, Shaker R. The Effect of Aging on Esophago-UES Relaxation Response Induced by Rapid Esophageal Air Distention. Accepted Poster DDW 2019 |
60. Mei L, Lynch S, Kovacic K, Crumb C, Shaker R. Variation of Basal UES Pressure within 2-minute Interval while Refraining Swallow. Accepted Poster DDW 2019. |
61. Kern M, Edeani F, Kovacic K, Sanvanson P, Mei L, Crumb C, Shaker R. Aberrant Striated Muscle Contractility in Symptomatic Patients with Normal Esophageal Manometry. Accepted Poster DDW 2019. |
62. Kern M, Agrawal D, Edeani F, Sanvanson P, Mei L, Shaker R. Effects of Strength Training on Deglutitive Pharyngeal Pressure Maps in Healthy Elderly Subjects. Accepted Poster DDW 2019 |
63. Kovacic K, Mei L, Lynch S, Kern M, Nelson, Crumb C, Shaker R. Effect of Acute Esophageal Acid Exposure on Striated Muscle Esophagus and UES Relaxation. Accepted Poster DDW 2019. |
64. Lynch S, Agrawal D, Mei L, Sanvanson P, Kern M, Shaker R. Initial Gains by Swallowing Against Laryngeal Restriction (SALR) Exercise in Dysphagic Patients Requires Maintenance Regimen to Sustain Effects. Accepted Poster DDW 2019 |
65. Lynch S, Agrawal D, Mei L, Sanvanson P, Kern M, Shaker R. Swallowing against Laryngeal Restriction (SALR) Exercise Technique Significantly Increases the Duration and Diameter of UES Opening in Both Healthy Elderly and Dysphagic Patients. Accepted Poster DDW 2019 |
66. Zhang N, Liang C, Wu I, Lu W, Sun D, Mei L, Jiao H. MANOMETRIC CHARACTERISTICS OF UPPER ESOPHAGEAL SPHINCTER AND STRIATED ESOPHAGEAL CONTRACTILITY IN PATIENTS WITH INEFFECTIVE ESOPHAGEAL MOTILITY |
67. Edeani FO, Saeian S, Kern M, Kovacic K, Mei L, Sanvanson P, Shaker R. Rapid Drinking Challenge May Help Distinguish Opioid-Associated Esophageal Dysmotility. Accepted DDW 2019 Poster |
68. Mei L, Patel K, Lehal N, Kern M, Benjamin A, Sanvanson P, etc., Sa1692 Fatigability of External Anal Sphincter Muscles During Various Exercise Methods Using a Novel Strength Training Resistance Exercise Device, Gastroenterology, Vol. 158, Issue 6, Supplement, S-385, Published in issue: May, 2020 |
69. Patel K, Mei L, Lehal N, Benjamin A, Sanvanson P, Kern M, etc. Sa1698 External Anal Sphincter Strength Training Exercise Using a Novel Continence Muscles Resistance Exerciser Device Results in Improved Anal Sphincter Contractility in Patients with Fecal Incontinence, Gastroenterology, Vol. 158, Issue 6, Supplement, S-388, Published in issue: May, 2020 |
70. Patel K, Mei L, Kern M, Sanvanson P, Lehal N, Edeani F, etc., Sa1699 Geometric Characteristics of the Anal Canal High-Pressure Zone During Repetitive Contraction Against a Resistive Load Can Help Define the Fatigability of Muscles Involved in Fecal Continence, Gastroenterology, Vol. 158, Issue 6, Supplement, S-388, Published in issue: May, 2020 |
71. Li J, Li L, Fu Z, Liu M, Mei L, Jiao H, Su 1360 The Effect of Proton Pump Inhibitor on the Image Quality of Magnetically Controlled Capsule Endoscopy in Aging Patients, Gastroenterology, Vol. 158, Issue 6, Supplement, S-565, Published in issue: May, 2020 |
72. Mei L, Edeani F, Sanvanson P, Kern M, Shaker R, 695 Isolated Sub-Ues Striated Esophageal Peristalsis in Response to Slow Simulated Reflux Events: Effect of Age and Chemical Composition, Gastroenterology, Vol. 160, Issue 6, Supplement, S-140-S-141, Published in issue: May, 2021 |
73. Kern M, Sanvanson P, Mei L, Edeani F, Agrawal D, Patel K, etc., Sa191 Normalized Impedance Isocontour Data in Patients with Ineffective Esophageal Motility (IEM) Exhibit Bolus Retention Proximal Esophagus as well as Globally Lower Baseline Impedance Values Compared to Healthy Controls, Gastroenterology, Vol. 106, Issue 6, Supplement, S-459, Published in issue: May, 2021 |
74. Kern M, Sanvanson P, Mei L, Edeani F, Agrawal D, Patel K, etc., Sa192 Patients with Diagnosis of IEM and those with Swallowing Complaint but Normal Manometry have Significantly Different Deglutitive Straited Esophagus Flow Dynamics Compared to Healthy Controls and Patients with Achalasia, Gastroenterology, Vol. 160, Issue 6, Supplement, S-459-S-460, Published in issue: May 2021 |
75. Patel K, Mei L, Lehal N, Sanvanson P, Kern K, Shaker R, Sa416 Fatigability of the Puborectalis Muscle by Repetitive Anal Contractions Against the Continence Muscles Resistance Exerciser Device, Gastroenterology, Vol. 160, Issue 6, Supplement, S-500-S-501, Published in issue: May, 2021 |
76. Edeani F, Kern M, Mei L, Yu E, Patel K, Sanvanson P, etc., Su188 Manometric Characteristics of Proximal Esophagus in 92 Asymptomatic Volunteers, Gastroenterology, Vol. 160, Issue 6, Supplement, S-641, Published in issue: May, 2021 |
77. Edeani F, Kern M, Mei L, Sanvanson P, Patel K, Kovacic K, etc., Su189 Effects of Bolus Volume on Upper Esophageal Sphincter Post-Deglutitive Contraction, Gastroenterology, Vol. 160, Issue 6, Supplement, S-641, Published in issue: May, 2021 |
78. Kern M, Sanvanson P, Mei L, Edeani F, Agrawal D, Patel K, etc., Su191 Effects of Swallowing Against Laryngeal Resistance (SALR) on Bolus Dynamics of the Esophageal Straited Muscle and Pharyngoesophageal Junction, Gastroenterology, Vol. 160, Issue 6, Supplement, S-642, Published in issue: May, 2021 |
79. Kern M, Sanvanson P, Mei L, Edeani F, Agrawal D, Patel K, etc., Su192 Correlation of the Striated Muscle Esophagus Pre-Peristaltic Liquid Bolus Dynamics with Pharyngeal Deglutitive Biomechanical Metrics, Gastroenterology, Vol. 160, Issue 6, Supplement, S-642-S-643, Published in issue: May, 2021 |
80. Kovacic K, Kern M, Mei L, Sancvanson P, Patel K, Lehal N, etc., Su201 Bolus Effect on Contractile Segment Impedance in Healthy Subjects, Gastroenterology, Vol. 160, Issue 6, supplement, S-646, Published in issues: May, 2021 |
81. Kovacic K, Kern M, Sanvanson P, Mei L, Edeani F, Shaker R, 266: General Anesthesia Using Sevoflurane, Alfentanil and Propofol Prior to Manometry Does Not Result in Abnormal Findings in Children Without Dysphagia, Gastroenterology Vol. 162Issue 7SupplementS-59Published in issue: May, 2022 |
82. Mei L, Edeani F, Yu E, Sanvanson P, Kern M, Shaker R, 1081: Further Characterization of Isolated Striated Esophagus Contraction as a Use Fortifying Mechanism Against Pharyngeal Reflux, Gastroenterology, Vol. 162, Issue 7, Supplement, S-251, Published in issue: May, 2022 |
83. Shaker R, Kern M, Edeani F, Mei L, Yu E, Sanvanson P, Sa1209: TEMPORO-SPATIAL MAPPING OF STRIATED ESOPHAGUS DEGLUTITIVE MOTOR FUNCTION, Gastroenterology, Vol. 162, Issue 7, Supplement, S-348, Published in issue: May, 2022 |
84. Edeani F, Kern M, Sanvanson P, Mei L, Yu E, Shaker R, Sa1213: Further Characterization of Striated Muscle Esophagus Contractile Function in Health and Disease, Gastroenterology, Vol. 162, Issue 7, Supplement, S-349–S-350, Published in issue: May, 2022 |
85. Kern M, Edeani F, Sanvanson P, Mei L, Shaker R, Su1240: Assessment of Bolus Injection Length (BIL): A Measure of Striated Esophageal Flow Dynamics by Mano-Impedance Compared to Video-Fluoroscopic Techniques, Gastroenterology, Vol. 162, Issue 7, Supplement, S-555–S-556, Published in issue: May, 2022 |
86. Kern M, Edeani F, Sanvanson P, Mei L, Shaker R, Su1243: Correlation of Striated Esophageal Flow Dynamics and Contractile Vigor: Difference Between Healthy Individuals and Patients, Gastroenterology, Vol. 162, Issue 7, Supplement, S-557, Published in issue: May, 2022 |
87. Kern M, Edeani F, Sanvanson P, Mei L, Shaker R, Su1244: The Effect of Aging on the Interaction Between Striated Esophageal Flow Dynamics and Contractile Vigor, Gastroenterology, Vol. 162, Issue 7, Supplement, S-557–S-558, Published in issue: May, 2022 |
88. Sanvanson P, Li Z, Medda B, Mei L, Shaker R, Mo1418: Impact of Vagotomy on Somatosensory Functional Networks in Rats Exposed to Esophageal ACID Infusion: An FCMRI Study, Gastroenterology, Vol. 162, Issue 7, Supplement, S-764, Published in issue: May, 2022 |
89. Yu E, Mehdi M, Mei L, Sanvanson P, Kern M, Shaker R, Tu1140: Reflux Associated Impedance Change in the Proximal Esophagus is not Accompanied by Changes in Contractility, Gastroenterology, Vol. 162, Issue 7, Supplement, S-899, Published in issue: May, 2022 |
90. Patel K, Mei L, Lehal N, Yu E, Kern M, Sanvanson P, etc., Su193 Effect of Respiration Pattern on Esophageal Motility Recorded by High Resolution Impedance Manometry, Gastroenterology, Vol. 160, Issue 6, Supplement, S-643, Published in issue: May, 2022 |
91. Mei, L; Yu, ES; Edeani, FO; Kern, M; Sanvanson, P; Shaker, R. Patients with Laryngo-Pharyngeal Reflux Demonstrate Impaired Striated Esophageal Response During Slow Simulated Acid Reflux Events and the Following Refluxate Dwell Periods. Gastroenterology 164 (6) S-821, May 2023. |
92. Kern, M; Edeani, FO; Sanvanson, P; Mei, L; Shaker, R. The Effect of Aging on the Interaction Between Striated Esophageal Peristaltic Velocity, Contractile Vigor and Flow Dynamics. Gastroenterology, 164 (6) S-828, May 2023. |
93. Kovacic, K; Kern, M; Sanvanson, P; Mei, L; Edeani, FO; Shaker, R. Substantial Number of Children with Esophageal Dysmotility are Erroneously Given Diagnosis of Normal Motility Per Chicago Classification. Gastroenterology, 164 (6) S-31, May 2023. |
94. Hassan, H; Shaker, R; Yu, ES; Kern, M; Edeani, FO; Sanvanson, P; Mei, L. Acute Esophageal Acid Exposure Sensitizes The Upper Esophageal Sphincter Relaxation Response to Esophageal Air Distension. Gastroenterology, 164 (6) S-1024-S-1025, May 2023. |
95. Edeani, FO; Shaker, R; Sanvanson, P; Mei, L; Hassan, H; Yu, ES; Kern, M. Patients with Diagnosis of Ineffective Esophageal Motility (IEM) Disorders Exhibit Abnormalities of Various Aspects of Striated Esophageal Motor Function. Gastroenterology, 164 (6) S-816, May 2023. |
96. Yu, ES; Sanvnason, P; Mehdi, M; Patel, K; Kern, M; Edeani, FO; Shaker, R; Mei, L. Patients with Laryngopharyngeal Complications of Reflux Disease (LPR) Exhibit Impaired UES Response to Simulated Ultra-Slow Reflux Events. Gastroenterology, 164 (6) S-568, May 2023. |
97. Yu, ES; Sanvanson, P; Mei, L; Edeani, FO; Hassan, H; Wells, M; Kern, M; Shaker, R. Feasibility and Safety of Concurrent Intragastric Pressure Measurements and Endoscopic Visualization of LES/GEJ Opening. Gastroenterology, 164 (6) S-1023-S-1024, May 2023. |
98. Kerschner, A; Hassan, H; Edeani, FO; Mei, L; Kern, M; Sanvanson, P; Shaker, R; Yu, ES. Parkinson's Disease is Associated with Decreased Striated Esophagus Contractility Potentially Contributing to Development of Dysphagia. Gastroenterology, 164 (6) S-818-S-819, May 2023. |
99. Mei, L; Hassan, H; Yu, Elliot; Kern, M; Weng, P; Edeani, FO; Sanvanson, P; Shaker, R. Fatigue Characteristics of Continence Muscles in Fecal Incontinent Patients. Gastroenterology, 166 (5) S-1384, May 2024. |