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CURRICULUM VITAE

Matthew Kudek MD
Assistant Professor
Department of Pediatrics
Division of Hematology and Oncology - Pediatrics

OFFICE ADDRESS:
Children's Hospital
9000 W Wisconsin Ave
Milwaukee, WI 53226

EDUCATION:
2005 - 2010 Bachelor of Science, Biomedical Engineering, University of Wisconsin, Madison, WI
2010 - 2014 Doctor of Medicine (M.D.), University of Wisconsin School of Medicine and Public Health, Madison, WI

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
2014 - 2017 Pediatric Internship and Residency, Certificate in Global Health, Pediatrics, University of Minnesota Medical School, Minneapolis, MN
2017 - 2018 Fellow, Medical Device Innovation Program, Institute for Engineering in Medicine, University of Minnesota, Minneapolis, MN
2018 - 2021 Pediatric Hematology, Oncology and Bone Marrow Transplant Fellow, Pediatrics, Pediatric Hematology, Oncology, Transplant, Medical College of Wisconsin, Milwaukee, WI
2020 - 2021 Chief Fellow, Pediatrics, Hematology, Oncology, BMT, Medical College of Wisconsin, Milwaukee, WI

FACULTY APPOINTMENTS:
2017 - 2018 Adjunct Assistant Professor, Pediatrics, Emergency Medicine, University of Minnesota, Minneapolis, MN
2021 - Present Assistant Investigator, Laboratory Research Track, Blood Research Institute, Versiti, Milwaukee, WI
2021 - Present Assistant Professor, Pediatrics, Hematology, Oncology, BMT, Medical College of Wisconsin, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:
2017 - 2018 Emergency Medicine Pediatrician, Pediatrics, Emergency Medicine, University of Minnesota Masonic Children's Hospital, Minneapolis, MN
2017 - 2018 Pediatrician, Hennepin County Medical Center, Minneapolis, MN
2021 - Present Pediatric Oncologist, Pediatrics, Hematology, Oncology, BMT, Children's Wisconsin, Milwaukee, WI 53151

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
American Board of Pediatrics, General Pediatrics Certification
2017
None
 
Licensure
Number Issue DateExpiration
Drug Enforcement Administration (DEA) Certification, Schedule II-V Prescribing License
2016
None
Minnesota State Medical Board
2016
2018
Wisconsin State Medical Board
2018
None
 

AWARDS AND HONORS:
2005 - 2010 Dean's List (9 semesters), University of Wisconsin College of Engineering
2007 Travel Stipend, Joint Molecular Imaging Conference
2007 Department of Biomedical Engineering Scholarship for Outstanding Performance from the Richard H. Thomas Family Scholarship, University of Wisconsin
2008 Tong Research and Development Award, University of Wisconsin - Madison, Madison, WI
2008 Invitation acceptance to Tau Beta Pi, a national engineering honor society
2009 People’s Choice Award, University of Wisconsin Engineering Expo; Madison, WI
2011 Wisconsin Medical Society Summer Fellowship Grant, Wisconsin Medical Society
2015 Abstract Achievement Award, American Society of Hematology
2016 Young Investigator Award, Pediatric Blood & Marrow Transplant Consortium
2018 Most Medically Impactful Venture, University of Minnesota & Mayo Clinic Walleye Tank Competition 2018 Spring Opener
2018 Most Scalable Venture Award, University of Minnesota & Mayo Clinic Walleye Tank Competition 2018 Spring Opener

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
Society for Immunotherapy of Cancer
American Society of Hematology
Minnesota Medical Association
Wisconsin Medical Alumni Asociation
American Society of Pediatric Hematology and Oncology

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Ad-Hoc Reviewer
2017 - Present Pediatric Emergency Care

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
CD19-20 CAR T Trial
Source:
Vince Lombardi Cancer Research Foundation
Role:
Co-investigator
PI:
Julie Talano
Dates:
2020 - Present
Direct Funds:
$4,444 (5% effort)
 
Title:
Dissecting the Cellular Mechanisms of Differential Outcomes of CD20-19 CAR-T Therapy in Acute Lymphoblastic Leukemia (ALL)
Source:
Children's Research Institute, Milwaukee WI
Role:
Co-investigator
PI:
Julie Talano
Dates:
2020 - Present
Direct Funds:
$4,444 (5% effort)
 
Title:
Pathogen Boosted Adoptive Cell Transfer for the Treatment of Neuroblastoma
Source:
St. Baldrick's Foundation Fellowship
Role:
Principal Investigator
Dates:
2021 - Present
Direct Funds:
$191,464
 

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Global Health Disparities Speaker Series, Engineering World Health, University of Minnesota Chapter, Minneapolis, MN, 04/05/2018
 
National
Promote Early Childhood Literacy for Spanish-Speaking Families: Leyendo Juntos!, 2016 American Academy of Pediatrics National Conference & Exhibition, San Francisco, CA, 10/22/2016 - 10/25/2016
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Student Education
2019 - 2020 Small-group presentation: Integrating the Foundations of Immunity. Component of the first-year medical student course “Infectious Agents and Host Immunity”.
 

PROGRAMMATIC DEVELOPMENTS:
 
 
Clinical Programs
2020 - Present COMPASS (Comprehensive Molecular Pathway Assessment) program. Partners include internal Pediatric Oncology, Genetics, Pharmacy and Dermatology, and an external molecular oncology program.
 
 

COMMUNITY SERVICE ACTIVITIES:
2016 - 2018 Outreach Chairman for Bethlehem Lutheran Church Leadership Council in Lakeville, Minnesota. Participated in leadership efforts for capital campaign for campus relocation. Additional responsibilities included supervision of outreach endeavors in Lakeville and Minneapolis communities, and the development, promotion and continued supervision of a sponsor partnership between our church members and young children of a Thailand community.
 

GLOBAL HEALTH ACTIVITIES:
2014 Uganda, Africa. Spent one month in Mbale, a small village in Uganda. Experiences included volunteering as a medical provider at Joy Hospice in Mbale and at Zion Medical Community Clinic in the village of Butooto. Developed and provided didactic seminars for community members on topics including childhood immunizations, the importance of proper hygiene, hand washing, bathing, and sickle cell disease.
2016 Bolivia, South America Spent six weeks in Cochabamba, Bolivia. Responsibilities included weekday obligations in a free, walk-in clinic in a rural community outside of Cochabamba. Additionally, helped implement a reading program in the school adjacent to the clinic, modeled after "Reach out and Read". Program entitled "Programa ABC: Ayudame a Brotar mi Cerebro." Launch of this program included selection of age-appropriate books, development of program name and logo, meetings with parents to explain the importance of reading with their children, and modeling various strategies of how to read with children. Program development model presented at 2016 Workshop at American Academy of Pediatrics National Conference & Exhibition.
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Schauder DM, Shen J, Chen Y, Kasmani MY, Kudek MR, Burns R, Cui W. E2A-regulated epigenetic landscape promotes memory CD8 T cell differentiation. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16). PMCID: PMC8072256
2. Topchyan P, Xin G, Chen Y, Zheng S, Burns R, Shen J, Kasmani MY, Kudek M, Yang N, Cui W. Harnessing the IL-21-BATF Pathway in the CD8<sup>+</sup> T Cell Anti-Tumor Response. Cancers (Basel). 2021 Mar 12;13(6). PMCID: PMC7998696
3. Phelan R, Eissa H, Becktell K, Bhatt N, Kudek M, Nuechterlein B, Pommert L, Tanaka R, Baker KS. Upfront Therapies and Downstream Effects: Navigating Late Effects in Childhood Cancer Survivors in the Current Era. Curr Oncol Rep. 2019 11 25;21(12):104.
4. Kudek MR, Shanley R, Zantek ND, McKenna DH, Smith AR, Miller WP. Impact of Graft-Recipient ABO Compatibility on Outcomes after Umbilical Cord Blood Transplant for Nonmalignant Disease. Biol Blood Marrow Transplant. 2016 11;22(11):2019-2024. PMCID: PMC5067229
5. Kudek MR, Luyet F, Herringa RJ, Knox BL. Restrictive Diet Control as a Means of Child Abuse. Pediatr Emerg Care. 2018 Mar;34(3):e57-e59.
6. Kudek MR, Knox BL. Sublingual hematoma: when to suspect child abuse. Clin Pediatr (Phila). 2014 Jul;53(8):809-12.
 
Abstracts
1. Kudek MR, Shen J, Xin G, Holzhauer S, Riese M, Cui W. Chronic viral infection in the absence of the α-isoform of diacylglycerol kinase leads to immune dysregulation and early host mortality. Medical College of Wisconsin – Department of Pediatrics Fellow Poster Session. Milwaukee, Wisconsin. March 22, 2021
2. Kudek MR, Phelan R, Talano J. A case of CVID with multifocal CNS complications successfully treated with allogeneic HSCT. Pediatric Transplantation and Cellular Therapy Consortium 8th Annual Meeting at American Society of Pediatric Hematology and Oncology Conference. Fort Worth, Texas. May 6, 2020. (meeting cancelled due to COVID-19)
3. Kudek MR, Shen J, Xin G, Cui W. Pathogen Booted Adoptive Cell Transfer Therapy for the Treatment of Bladder Cancer. Medical College of Wisconsin – Department of Pediatrics Fellow Poster Session. Milwaukee, Wisconsin. April 6, 2020
4. Kudek MR, Knipstein J, Zimbric K, Schloemer N. Minimizing MEK-related maladies: a protocol to ensure safe delivery of MEK-inhibitors for inoperable plexiform neurofibromas. Children’s Hospital of Wisconsin 6th Annual Pediatric Cancer Symposium. Milwaukee, Wisconsin. May 9, 2019.
5. Kudek MR, Knipstein J, Zimbric K, Schloemer N. MEK-ing a plan to treat NF: Safe delivery of MEK-inhibitors for inoperable plexiform neurofibromas. American Society of Pediatric Hematology and Oncology 32nd Annual Meeting. Pediatric Blood and Cancer 2019 66:e27713. S105. New Orleans, Louisiana. May 1-4, 2019.
6. Goodwin K, Kudek M, Smith S, Tracy P. Disciplined Innovation – a device development process to solve unmet clinical needs. University of Minnesota Department of Surgery Research Day. May 22, 2018. Minneapolis, Minnesota
7. Kudek MR, Eagle S, Sadak KT. A Model for Delivering Education on Health Care Insurance to Adolescent and Young Adult Survivors of Childhood Cancer. 15th International Conference on Long-Term Complications of Treatment of Children and Adolescents for Cancer. June 15-17, 2017. Atlanta, Georgia.
8. Gillett A, Cafferty R, Campbell J, Kudek MR, Wilson N, Gutowski E. Improving Hepatitis B Vaccination Rates Among Neonates in a Local Newborn Nursery. Metro Minnesota Council on Graduate Medical Education 4th Annual Quality Forum. May 25, 2016. Minneapolis, Minnesota.
9. Kudek MR, Shanley R, Zantek ND, Smith AR, Miller WP. The Impact of Graft-Recipient ABO Compatibility on Outcomes after Umbilical Cord Blood Transplant for Non-Malignant Disease. American Society of Hematology 57th Annual Meeting. Blood 2015 126(23) 4369. Orlando, Florida. December 3-8, 2015.
10. Kudek MR, Shanley R, Zantek ND, Smith AR, Miller WP. The Impact of Graft-Recipient ABO Compatibility on Outcomes after Umbilical Cord Blood Transplant for Non-Malignant Disease. Pediatric Blood and Marrow Transplant Consortium / American Society of Pediatric Hematology and Oncology 4th Annual Joint Conference. Minneapolis, Minnesota. May 11-14, 2016.
11. Kudek MR, Christensen MB, Durkee BY, Weichert JP. MicroPET/CT Evaluation of 124I-NM404 in a Murine Sarcoma Model. 6th Annual Joint Molecular Imaging Conference. Providence, Rhode Island. September 8-11, 2007
 
Patents
1. Kudek MR. Intraoral Device and Method for the Use Thereof. PCT and US application. Application number: 16/354,766
2. Cho RJ, Landaeta F, Kudek MR. Multi-compartment Syringe with Hand Pump Mechanism. Application number: 15/733,552