Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

CURRICULUM VITAE

Matthew Kudek MD
Assistant Professor
Department of Pediatrics
Division of Hematology and Oncology - Pediatrics

OFFICE ADDRESS:
Children’s Wisconsin - Milwaukee Hospital
8915 W Connell Court
Milwaukee, WI 53226

EDUCATION:
2005 - 2010 Bachelor of Science, Biomedical Engineering, University of Wisconsin, Madison, WI
2010 - 2014 Doctor of Medicine (M.D.), University of Wisconsin School of Medicine and Public Health, Madison, WI

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
2014 - 2017 Pediatric Internship and Residency, Certificate in Global Health, Pediatrics, University of Minnesota Medical School, Minneapolis, MN
2018 - 2021 Pediatric Hematology, Oncology and Bone Marrow Transplant Fellow, Pediatrics, Pediatric Hematology, Oncology, Transplant, Medical College of Wisconsin, Milwaukee, WI
2020 - 2021 Chief Fellow, Pediatrics, Hematology, Oncology, BMT, Medical College of Wisconsin, Milwaukee, WI

FACULTY APPOINTMENTS:
2017 - 2018 Adjunct Assistant Professor, Pediatrics, Emergency Medicine, University of Minnesota, Minneapolis, MN
2021 - Present Assistant Investigator, Laboratory Research Track, Blood Research Institute, Versiti, Milwaukee, WI
2021 - Present Assistant Professor, Pediatrics, Hematology, Oncology, BMT (Primary) | Microbiology and Immunology (Secondary), Medical College of Wisconsin, Milwaukee, WI


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Nguyen C, Kudek M, Zander R, Niu H, Shen J, Bauer A, Alson D, Khatun A, Chen Y, Sun J, Drobyski W, Edelson BT, Cui W. Bhlhe40 Promotes CD4+ T Helper 1 Cell and Suppresses T Follicular Helper Cell Differentiation during Viral Infection. J Immunol. 2024 Jun 01;212(11):1829-1842.
2. Kasmani MY, Topchyan P, Brown AK, Brown RJ, Wu X, Chen Y, Khatun A, Alson D, Wu Y, Burns R, Lin CW, Kudek MR, Sun J, Cui W. A spatial sequencing atlas of age-induced changes in the lung during influenza infection. Nat Commun. 2023 Oct 18;14(1):6597. PMCID: PMC10584893
3. Khatun A, Wu X, Qi F, Gai K, Kharel A, Kudek MR, Fraser L, Ceicko A, Kasmani MY, Majnik A, Burns R, Chen YG, Salzman N, Taparowsky EJ, Fang D, Williams CB, Cui W. BATF is Required for Treg Homeostasis and Stability to Prevent Autoimmune Pathology. Adv Sci (Weinh). 2023 Oct;10(28):e2206692. PMCID: PMC10558681
4. Kharel A, Shen J, Brown R, Chen Y, Nguyen C, Alson D, Bluemn T, Fan J, Gai K, Zhang B, Kudek M, Zhu N, Cui W. Loss of PBAF promotes expansion and effector differentiation of CD8<sup>+</sup> T cells during chronic viral infection and cancer. Cell Rep. 2023 Jun 27;42(6):112649. PMCID: PMC10592487
5. Kudek MR, Xin G, Alson D, Holzhauer S, Shen J, Kasmani MY, Riese M, Cui W. Lymphocytic Choriomeningitis Virus Clone 13 Infection Results in CD8 T Cell-Mediated Host Mortality in Diacylglycerol Kinase α-Deficient Mice. J Immunol. 2023 May 01;210(9):1281-1291. PMCID: PMC10121876
6. Kimball BC*, Kudek MR*, van Ly D, Eagle S, Hausman V, Plaunt E, Lee HY, Sadak KT. Empowering childhood cancer survivors through integrated, individualized health insurance education Precision Cancer Medicine. December 2021;4. (* denotes co-first authorship)
7. Schauder DM, Shen J, Chen Y, Kasmani MY, Kudek MR, Burns R, Cui W. E2A-regulated epigenetic landscape promotes memory CD8 T cell differentiation. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16). PMCID: PMC8072256
8. Topchyan P, Xin G, Chen Y, Zheng S, Burns R, Shen J, Kasmani MY, Kudek M, Yang N, Cui W. Harnessing the IL-21-BATF Pathway in the CD8<sup>+</sup> T Cell Anti-Tumor Response. Cancers (Basel). 2021 Mar 12;13(6). PMCID: PMC7998696
9. Phelan R, Eissa H, Becktell K, Bhatt N, Kudek M, Nuechterlein B, Pommert L, Tanaka R, Baker KS. Upfront Therapies and Downstream Effects: Navigating Late Effects in Childhood Cancer Survivors in the Current Era. Curr Oncol Rep. 2019 Nov 25;21(12):104.
10. Kudek MR, Shanley R, Zantek ND, McKenna DH, Smith AR, Miller WP. Impact of Graft-Recipient ABO Compatibility on Outcomes after Umbilical Cord Blood Transplant for Nonmalignant Disease. Biol Blood Marrow Transplant. 2016 Nov;22(11):2019-2024. PMCID: PMC5067229
11. Kudek MR, Luyet F, Herringa RJ, Knox BL. Restrictive Diet Control as a Means of Child Abuse. Pediatr Emerg Care. 2018 Mar;34(3):e57-e59.
12. Kudek MR, Knox BL. Sublingual hematoma: when to suspect child abuse. Clin Pediatr (Phila). 2014 Jul;53(8):809-12.
 
Abstracts
1. Kudek MR, Xin G, Holzhauer S, Alson T, Shen J, Kasmani M, Riese M, Cui W. CD8 T Cells Mediate Host Death Following Lcmv Clone 13 Infection in DGK alpha Deficiency. American Society of Hematology 64th Annual Meeting. New Orleans, Louisiana. December 10-13, 2022
2. Kudek MR, Shen J, Xin G, Holzhauer S, Riese M, Cui W. Chronic viral infection in the absence of the alpha isoform of diacylglycerol kinase leads to immune dysregulation and early host mortality. Medical College of Wisconsin – Department of Pediatrics Fellow Poster Session. Milwaukee, Wisconsin. March 22, 2021
3. Kudek MR, Phelan R, Talano J. A case of CVID with multifocal CNS complications successfully treated with allogeneic HSCT. Pediatric Transplantation and Cellular Therapy Consortium 8th Annual Meeting at American Society of Pediatric Hematology and Oncology Conference. Fort Worth, Texas. May 6, 2020. (meeting cancelled due to COVID-19)
4. Kudek MR, Shen J, Xin G, Cui W. Pathogen Booted Adoptive Cell Transfer Therapy for the Treatment of Bladder Cancer. Medical College of Wisconsin – Department of Pediatrics Fellow Poster Session. Milwaukee, Wisconsin. April 6, 2020
5. Kudek MR, Knipstein J, Zimbric K, Schloemer N. Minimizing MEK-related maladies: a protocol to ensure safe delivery of MEK-inhibitors for inoperable plexiform neurofibromas. Children’s Hospital of Wisconsin 6th Annual Pediatric Cancer Symposium. Milwaukee, Wisconsin. May 9, 2019.
6. Kudek MR, Knipstein J, Zimbric K, Schloemer N. MEK-ing a plan to treat NF: Safe delivery of MEK-inhibitors for inoperable plexiform neurofibromas. American Society of Pediatric Hematology and Oncology 32nd Annual Meeting. Pediatric Blood and Cancer 2019 66:e27713. S105. New Orleans, Louisiana. May 1-4, 2019.
7. Goodwin K, Kudek M, Smith S, Tracy P. Disciplined Innovation – a device development process to solve unmet clinical needs. University of Minnesota Department of Surgery Research Day. May 22, 2018. Minneapolis, Minnesota
8. Kudek MR, Eagle S, Sadak KT. A Model for Delivering Education on Health Care Insurance to Adolescent and Young Adult Survivors of Childhood Cancer. 15th International Conference on Long-Term Complications of Treatment of Children and Adolescents for Cancer. June 15-17, 2017. Atlanta, Georgia.
9. Gillett A, Cafferty R, Campbell J, Kudek MR, Wilson N, Gutowski E. Improving Hepatitis B Vaccination Rates Among Neonates in a Local Newborn Nursery. Metro Minnesota Council on Graduate Medical Education 4th Annual Quality Forum. May 25, 2016. Minneapolis, Minnesota.
10. Kudek MR, Shanley R, Zantek ND, Smith AR, Miller WP. The Impact of Graft-Recipient ABO Compatibility on Outcomes after Umbilical Cord Blood Transplant for Non-Malignant Disease. American Society of Hematology 57th Annual Meeting. Blood 2015 126(23) 4369. Orlando, Florida. December 3-8, 2015.
11. Kudek MR, Shanley R, Zantek ND, Smith AR, Miller WP. The Impact of Graft-Recipient ABO Compatibility on Outcomes after Umbilical Cord Blood Transplant for Non-Malignant Disease. Pediatric Blood and Marrow Transplant Consortium / American Society of Pediatric Hematology and Oncology 4th Annual Joint Conference. Minneapolis, Minnesota. May 11-14, 2016.
12. Kudek MR, Christensen MB, Durkee BY, Weichert JP. MicroPET/CT Evaluation of 124I-NM404 in a Murine Sarcoma Model. 6th Annual Joint Molecular Imaging Conference. Providence, Rhode Island. September 8-11, 2007
 
Patents
1. Inventor: Kudek MR. Intraoral Device and Method for the Use Thereof. US Patent Number: 11,154,459. October 26, 2021.
2. Co-inventors: Cho RJ, Landaeta F, Kudek MR. Multi-compartment Syringe with Hand Pump Mechanism. Application number: 15/733,552