CURRICULUM VITAE
Maya S. Safarova MD, PhD
Maya S. Safarova MD, PhD
Assistant Professor
Department of Medicine
Division of Cardiology
Department of Medicine
Division of Cardiology
OFFICE ADDRESS: |
Froedtert Hospital |
9200 W Wisconsin Ave |
Milwaukee, WI 53226 |
EDUCATION: |
09/2003 - 07/2009 MD, First Moscow State Medical University, Moscow, Russia |
09/2009 - 06/2013 Clinician-Investigator track, Resident/Fellow, Myasnikov Institute of Clinical Cardiology, National Medical Research Cent |
09/2009 - 06/2013 PhD (Exploring Causality of Lipoprotein(a) in Atherosclerosis Among Patients with Stable Coronary He, National Medical Research Center for Cardiovascular Medicine, Moscow, Russia |
07/2013 - 12/2014 Staff Cardiologist, Department of Atherosclerosis, Myasnikov Institute of Clinical Cardiology, National Medical Research Cent |
12/2014 - 06/2017 Postdoctoral Fellow, Atherosclerosis and Lipid Genomics Laboratory, Department of Cardiovascular Medicine, Mayo Clinic |
07/2017 - 06/2020 Medicine Resident, Department of Internal Medicine, Cooperman Barnabas Medical Center, Rutgers New Jersey Medical Sch |
07/2020 - 06/2023 Cardiology Fellow, Department of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City |
06/2022 - Present Fellow of the National Lipid Association |
01/2024 - Present Fellow of the American College of Cardiology |
03/2024 - Present Fellow of the American Heart Association |
POSTGRADUATE TRAINING AND FELLOWSHIP: |
FACULTY APPOINTMENTS: |
10/2013 - 12/2014 Instructor in Medicine, National Medical Research Center for Cardiovascular Medicine, Moscow, Russia |
08/2023 - Present Clinician-Scientist, Assistant Professor, Consultant, Department of Internal Medicine, Division of Cardiovascular Medicine, The Medical College of Wisconsin, Milwaukee, WI |
EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: |
07/2022 - 06/2023 Chief Cardiology Fellow, University of Kansas Medical Center, Kansas City, KS |
HOSPITAL STAFF PRIVILEGES: |
08/2023 - Present Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Ave., Milwaukee, WI 53226 |
08/2023 - Present Froedtert Menomonee Falls Hospital, W180 N8085, Town Hall Rd, Menomonee Falls, WI 53051 |
08/2023 - Present Froedtert West Bend Hospital, 3200 Pleasant Valley Rd, West Bend, WI 53095 |
SPECIALTY BOARDS AND CERTIFICATION: |
Board Certified | Issue Date | Expiration |
Internal Medicine Board, Russia | 2010 | 2015 |
Cardiovascular Board, Russia | 2011 | 2016 |
Echocardiography Certification, Russia | 2012 | 2017 |
American Board of Internal Medicine Certification | 08/2020 | None |
American Board of Clinical Lipidology Certification | 12/2021 | None |
National Board of Echocardiography (Level 3) | 07/2022 | None |
Certification Board of Nuclear Cardiology (Level 2) | 12/2022 | None |
ABIM Cardiovascular Disease Certification | 10/2023 | None |
Certificates | Issued By | Issue Date | Expiration |
ACLS | AHA | 11/2013 | 08/2026 |
CPR BLS | AHA | 11/2013 | 08/2026 |
Licensure | Number | Issue Date | Expiration |
New Jersey License | 18-00370 | 06/18/2018 | 06/30/2020 |
Kansas License | 94-10148 | 06/01/2020 | 06/30/2023 |
Missouri License | 202-103-8863 | 09/22/2021 | 06/30/2023 |
Wisconsin License | 82250 | 06/12/2023 | 10/31/2025 |
AWARDS AND HONORS: |
2007 - Present NycoMed: Golden Fellows of Medicine Merit Scholarship, Moscow, Russia |
2008 - Present First Place, Internal Medicine Jeopardy, First Moscow State Medical University, Moscow, Russia |
2009 - Present Golden Stethoscope Award, First Moscow State Medical University, Moscow, Russia |
2011 - Present Young Investigator Award, Russian National Congress 'Human and Medicine', Moscow, Russia |
2011 - Present Second Poster Prize, 8th International Society for Apheresis Congress, Vienna, Austria |
2012 - Present Best Poster Prize, 80th European Atherosclerosis Society Congress, Milan, Italy |
2012 - Present American Heart Association International Mentoring Travel Award, Los Angeles, CA |
2012 - Present European Atherosclerosis Society Travel Grant Award, Milan, Italy |
2013 - Present Presenter of the Year Award, First Healthcare Channel, Russia |
2013 - Present Young Investigator Award, 50th National Congress of Cardiology, St Petersburg, Russia |
2014 - Present European Society of Cardiology Travel Grant Award, Barcelona, Spain |
2015 - Present American Heart Association Midwest Affiliate Postdoctoral Fellowship Award |
2016 - Present Jay D. Coffman Early Career Investigator Award, American Heart Association |
2017 - Present Young Investigator Award, Clinical Investigation Track, American College of Cardiology, Washington, DC |
2019 - 2020 Ambulatory Care Medicine Award, Rutgers New Jersey Medical School, Robert Wood Johnson-Saint Barnabas Medical Center, Livingston, NJ |
2020 - Present Outstanding Graduating Resident Award, Rutgers New Jersey Medical School, Robert Wood Johnson-Saint Barnabas Medical Center, Livingston, NJ |
2021 - Present American College of Cardiology, Legislative Conference Travel Award, Washington, DC |
06/2022 - Present Young Investigator Award, Genomic Medicine Course, Children's Mercy Hospital, Kansas City, MO |
10/2022 - Present Best Poster Prize, Kansas Chapter American College of Cardiology, Kansas City, KS |
10/2022 - Present FIT Jeopardy Finalist, Kansas Chapter American College of Cardiology, Kansas City, KS |
06/2023 - Present SHARP Scholarship Award, Epigenetics Boot Camp, Columbia University, New York City, New York |
06/2025 - 2025 Foundation of the National Lipid Association Young Investigator Award (second place), "The promise of progress in cardiovascular residual risk reduction: a complex case of lipoprotein management in pr, FL |
2025 - Present MCW Faculty Development Award, Milwaukee, WI |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
2011 - Present European Society of Cardiology - Council on Cardiovascular Genomics |
2012 - Present American Heart Association - Council on Arteriosclerosis (Thrombosis and Vascular Biology and Council on Genomic and Precision Medicine (GPM)) |
2013 - Present National Lipid Association |
2015 - Present American Society of Human Genetics |
2017 - 2020 American College of Physicians |
2020 - Present American College of Cardiology |
2020 - Present American Society For Apheresis |
2020 - 2023 American Society of Echocardiography |
2021 - 2022 American Society of Nuclear Cardiology |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorship |
2013 - 2014 Member, Journal of Atherosclerosis and Dyslipidaemias |
08/2022 - 03/2025 Deputy Editor, European Heart Journal Case Reports |
10/2022 - 12/2023 Guest Associate Editor, Cardiovascular Genetics and Systems Medicine, Frontiers in Cardiovascular Medicine |
11/2023 - 01/2024 Guest Editor in Epigenetics and Epigenomics, Frontiers in Genetics |
04/2024 - 01/2025 Academic Editor, International Journal of Vascular Medicine |
Journal Review |
10/202 - Present New Amsterdam Pharma |
2021 - 2022 Reviewer, AHA Grant applications to Study COVID effects on the Cardiovascular System |
04/2024 - Present Reviewer, MCW Cardiovascular Center Pilot Award Study Section |
10/2024 - Present Reviewer, AHA Genomics and Translational Biology Fellowship Committee |
11/2024 - Present Novartis |
Journal of the American Heart Association |
American Journal of Cardiology |
Atherosclerosis |
Journal of Clinical Lipidology |
Journal of Clinical Apheresis |
Therapeutic Apheresis and Dialysis |
Abstract Reviewer |
American Heart Association |
American College of Cardiology |
American Medical Informatics Association Annual symposium |
American Association of Human Genetics (DNA Essay Contest Judge) |
American Society For Apheresis |
Study Section Participation |
Advisory Board Member |
European Heart Journal |
Circulation: Genomic and Precision Medicine |
Circulation |
Journal of the American Society of Echocardiography |
Journal of the American Medical Association |
Journal of the American College of Cardiology |
Annals of Internal Medicine |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2017 - 2018 Resident Council Representative, Cooperman Barnabas Medical Center, Livingston, NJ |
2017 - 2019 Representative, New Jersey American College of Physicians Council of Resident/Fellow Members |
2018 - 2019 Resident Representative, Patient Safety and Quality Improvement Committee, Cooperman Barnabas Medical Center, Livingston, NJ |
06/2019 - 06/2020 Liaison, Peripheral Vascular Disease Council to the Clinical Cardiovascular Disease and Stroke in Women and Special Populations Committee |
07/2020 - 06/2023 Liaison, AHA Council on Clinical Cardiology, CLCD Cardiovascular Disease & Stroke in Women & Special Populations Committee |
07/2021 - 06/2023 Member, GME Faculty Development Subcommittee, KUMC |
07/2021 - 06/2023 Fellowship Mentoring Program for Residents and Students, The University of Kansas Medical Center |
07/2021 - 06/2023 Member, Cardiovascular Fellowship Program Evaluation Committee, The University of Kansas Medical Center |
10/2021 - 10/2022 Moderator, Organizing Committee, Annual KU Cardiovascular Medicine Research Day Organizing Committee |
01/2022 - 2023 Reviewer, ACC Young Scholars Application Grading Committee |
06/2022 - 2024 Mentor, ACC Cardiology Applicant Mentorship Program |
09/2022 - 06/2023 Member, Cardiology Fellowship Applicant Review Committee, The University of Kansas Medical Center |
02/2023 - Present Abstract Committee Member, American Society for Apheresis |
06/2023 - Present Abstract Committee Member, American Heart Association |
10/2023 - Present Co-Chair, Pharmacogenomics Committee, Medical College of Wisconsin |
03/2024 - Present Member, Wisconsin-American College of Cardiology Board of Councilors |
10/2024 - Present the Familial Hypercholesterolemia Variant Curation Expert Panel (VCEP), NIH-funded Clinical Genome Resource (ClinGen, clinicalgenome.org); final variant classifications are publicly available in ClinVar and published at 3-star "expert panel" status with FDA recognition |
11/2024 - Present Abstract Committee Member, American College of Cardiology |
11/2024 - Present Member, Genetic Counseling Taskforce, Medical College of Wisconsin |
11/2024 - Present Board Member, European Society of Cardiology |
01/2025 - 06/2026 Member, The Medical College of Wisconsin Affiliated Hospitals (MCWAH) Research and QI Award Committee |
04/2025 - Present Member, American College of Cardiology Prevention of Cardiovascular Disease Section Leadership Council |
07/01/2025 - 06/30/2028 Member, the Research Affairs Committee, Medical College of Wisconsin |
NATIONAL/INTERNATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
International |
3. Co-Chair, Abstract Session: Therapeutic Apheresis, American Society for Apheresis (ASFA) Scientific Sessions, Montreal, Canada, 04/08/2025 - Present |
1. Atherosclerosis and beyond: emerging lipid-lowering drugs. Lomonosov Moscow State University, Moscow, - 12/2011 |
2. Lp(a) apheresis for coronary atherosclerosis regression. 80th European Atherosclerosis Society Congress. Milan, - 05/2012 |
National |
15 - Present |
16 - Present |
24. Panelist, Fellow-in-training. Mix 'N' Mingle, ACC Prevention Section, Chicago, IL, 03/29/2025 - Present |
7. Lipoprotein(a): an evolving therapeutic target. Cardiovascular Conference, University of Kansas Hospital and Medical Center, Kansas City, - 05/2021 |
8. Lipid Disorders in the Age of Genomics. Internal Medicine Grand Rounds, Rutgers New Jersey Medical School/Saint Barnabas Medical Center, Livingston, - 06/2021 |
9. Strain Imaging Echocardiography: Twists and Turns, And Lessons Learned. All-staff Echocardiography Conference, University of Kansas Hospital and Medical Center, Kansas City, - 01/2022 |
10. Women in Cardiology for Medical Students. University of Kansas Hospital and Medical Center, Kansas City, - 03/31/2022 |
11. Duty to Warn: Welcome to the Genomic Era. Humanities Conference, Department of Internal Medicine, Rutgers New Jersey Medical School/Cooperman Barnabas Medical Center, New Brunswick, - 04/22/2022 |
12. Vascular age in patients with severe hypercholesterolemia treated with lipoprotein apheresis. American Society for Apheresis, Philadelphia, - 05/06/2022 |
13. Lipid Disorders in the Age of genomics: Teaching Old Dogmas New Tricks. Cardiovascular Grand Rounds, University of Nebraska Medical Center, Omaha, - 08/03/2022 |
14. Vascular Aging Through Understanding of Inherited Basis of Familial Hypercholesterolemia. Stanford Prevention Research Center, Division of Cardiovascular Medicine, Palo Alto, - 08/24/2022 |
17. Lipid Disorders in the Age of Genomics: Emerging Non-Statin LDL Lowering Agents. National Lipid Association Scientific Association Scientific Sessions |
18. Moderator, Polygenic Risk Scores for Cardiovascular Disease - Opportunities and Challenges for Clinical Implementation. AHA Scientific Sessions, Philadelphia, - 11/2023 |
19. Moderator, From the Basics to NextGen Therapeutics For CVD Prevention. ACC Scientific Sessions, Atlanta, - 04/07/2024 |
20. Exploring Options in the Management of PAD in Patients with FH and Lp(a), ACC and Kaneka, Atlanta, - 04/07/2024 |
21. Invited talk. Cardiovascular Residual Risk: Case Presentation. Translating 'Almost' 100 Years of Lipoprotein Research: Current and Future Lipoprotein Interventions - Its All in the Mechanism, AHA scientific sessions, Chicago, - 11/17/2024 |
22. Moderator, Clinical and Translational Studies of Lipoproteins and Lipids in Vascular Diseases. AHA Scientific Sessions, Chicago, - 11/16/2024 |
23. Co-Chair, Ask The Experts Your Burning Questions on Cardiovascular Risk Factor Management and Prevention. ACC Scientific Sessions, Chicago, - 03/30/2025 |
25. Monogenic Familial Hypercholesterolemia; Historical Perspective and Current Directions, NLA Scientific Sessions, Miami, - 05/31/2025 |
26. Expert Theater, Approach to Lower Extremity PAD in FH and Elevated Lp(a), NLA Scientific Sessions, Miami, - 05/31/2025 |
6. Top 10 Clinical Trials of the Year, What's New? Kansas Chapter of ACC. Leawood, - 10/2020 |
5. Identification of Familial Hypercholesterolemia from Electronic Health Records: the SEARCH study. Cardiovascular Research Seminar, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, - 06/2017 |
4. A Phenome-wide association study to uncover pleiotropic effects of PCSK9. Cardiovascular Research Seminar, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, - 03/2017 |
3. Variability in assigning pathogenicity to incidental findings: insights from LDLR sequence linked to the electronic health record in 1013 individuals. eMERGE Network Steering Committee meeting. Washington, - 10/2016 |
2. A Phenome-wide association study to uncover pleiotropic effects of PCSK9. eMERGE Network Steering Committee meeting, Bethesda, - 05/2016 |
1. Lp(a) apheresis and Atherosclerosis. Scientific Advisory Board for ISIS/IONIS-Apo(a) Rx (Ionis Pharmaceuticals), Los Angeles, - 11/2012 |
Regional |
7 - Present |
2. Lipid Clinic Bootcamp 101: Recognizing inherited lipid disorders, APP educational session, West Bend, WI, 10/01/2024 - Present |
9. Interview, Spectrum News 1 Wisconsin, "Lipid clinic provides crucial treatment for cardiovascular patients, " Milwaukee, WI, 02/06/2025 - Present |
1. Lipoprotein(a): an evolving therapeutic target, Cardiovascular Grand Rounds, The Medical College of Wisconsin |
3. Women and Heart Disease: Sex and Gender in CV Health. The Medical College of Wisconsin, Milwaukee, - 02/01/2024 |
4. Lipid Clinic 2024: Recognizing inherited lipid disorders, how to manage and who to refer, The Wisconsin Chapter ACC scientific sessions, Milwaukee, - 10/05/2024 |
5. CTSI Science Cafe Presentation series. Heart Health and Cholesterol: When an ounce of prevention is worth a pound of cure, Milwaukee, - 08/2024 |
6. Lipoprotein Apheresis: An Update. Cardiovascular Division Meeting, MCW |
8. Managing PAD in Patients with FH and Elevated Serum Lp(a): Insights from Two Clinical Cases. Milwaukee, WI. 03/2025 (Sponsored CME event, Kaneka) |
MCW TEACHING ACTIVITIES: |
Medical Student Education |
10/26/2024 - Present Judge, Poster session, MCW Department of Medicine 11th Annual Research Retreat, Milwaukee, WI. |
10/26/2024 - Present Judge, Poster session, Regional Asian Pacific American Student Association (APAMSA) Conference, Milwaukee, WI. |
03/21/2025 - Present Panelist, focus group discussion, Research Mentorship Event, Clinician Scientist Initiative |
Annual Women and Heart Disease: Sex and Gender in CV Health (Cardiovascular Fusion series, MS1). The Medical College of Wisconsin, Milwaukee, WI. |
Graduate Student Education |
01/2024 - 06/2025 Co-Director, Translational Genomics Course |
03/10/2025 - Present Translation Study Design and Strategy |
Resident and Fellow Education |
08/2023 - Present Consult service and Lipid Clinic at the Froedtert Health Network |
04/17/2024 - Present Vascular Aging: Aortopathies in General Cardiology Practice |
05/23/2024 - Present The Iron Claw of Cardiovascular Prevention: Breaking the Curse with Lipoprotein Apheresis |
03/20/2025 - Present Approaches to Genetic Screening in Cardiomyopathies |
EXTRAMURAL TEACHING: |
Graduate Student Education |
2011 - 2014 Nadezhda Artemeva MD, Cardiology fellow, National Medical Research Center for Cardiovascular Medicine, PhD theses "Lipoprotein particle size and coronary artery disease." |
2012 - 2014 Renad Adzhiev MD, Cardiology fellow, National Medical Research Center for Cardiovascular Medicine, PhD theses "Effect of double filtration plasmapheresis on the severity of vein graft disease in patients with stable ischemic heart disease." |
2014 - Present Anna Burdeynaya MD, Cardiology fellow, National Medical Research Center for Cardiovascular Medicine, PhD theses "Role of atherogenic lipoproteins in the development of degenerative aortic valve stenosis." |
2015 - Present Sandya Dandluri MD, trainee, Mayo Clinic Rochester, research project "Rapid identification of familial hypercholesterolemia from electronic health records." |
2016 - Present Nahal Nikroo, medical student, Mayo Clinic Rochester, research project "Association of variation in 84 pharmacogenes with LDL cholesterol levels." |
2017 - Present Magdi Zordok MD, research trainee, Mayo Clinic, research project "Community-based study of familial hypercholesterolemia." |
2023 - 2025 Leili Behrooz, Cardiovascular fellow, and Natalia Tovar, MS1, MCW, WI, research project "Low-density lipoprotein cholesterol goal attainment and cardiovascular outcomes in patients with lower extremity peripheral arterial disease." |
2023 - 2024 Tia Bimal, Cardiovascular prevention fellow, Northwell Health, NY, research project "Prevalence and Mechanisms of Ineffective Subtilisin/Kexin Type 9 (PCSK9) Inhibitors Monotherapy." |
2024 - 2025 Michelle Knezevich, MS, data analyst, Cardiovascular Research Center, "Estimated Prevalence of Ineffective Therapy with Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Real-World Data in the Academic Health System." |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Ezhov M, Safarova M, Afanasieva O, Mitroshkin M, Matchin Y, Pokrovsky S. Matrix Metalloproteinase 9 as a Predictor of Coronary Atherosclerotic Plaque Instability in Stable Coronary Heart Disease Patients with Elevated Lipoprotein(a) Levels. Biomolecules. 2019 Mar 29;9(4). PMCID: PMC6523150 |
2. Kullo IJ, Olson J, Fan X, Jose M, Safarova M, Radecki Breitkopf C, Winkler E, Kochan DC, Snipes S, Pacyna JE, Carney M, Chute CG, Gupta J, Jose S, Venner E, Murugan M, Jiang Y, Zordok M, Farwati M, Philogene M, Smith E, Shaibi GQ, Caraballo P, Freimuth R, Lindor NM, Sharp R, Thibodeau SN. The Return of Actionable Variants Empirical (RAVE) Study, a Mayo Clinic Genomic Medicine Implementation Study: Design and Initial Results. Mayo Clin Proc. 2018 Nov;93(11):1600-1610. PMCID: PMC6652203 |
3. Liao X, Norata GD, Polak JF, Stehouwer CD, Catapano A, Rundek T, Ezhov M, Sander D, Thompson SG, Lorenz MW, PROG-IMT study group, Balakhonova T, Safarova M, Grigore L, Empana JP, Lin HJ, McLachlan S, Bokemark L, Ronkainen K, Schminke U, Lind L, Willeit P, Yanez DN, Steinmetz H, Poppert H, Desvarieux M, Ikram MA, Johnsen SH, Iglseder B, Friera A, Xie W, Plichart M, Su TC, Srinivasan SR, Schmidt C, Tuomainen TP, Völzke H, Nijpels G, Willeit J, Franco OH, Suarez C, Zhao D, Ducimetiere P, Chien KL, Robertson C, Bergström G, Kauhanen J, Dörr M, Dekker JM, Kiechl S, Sitzer M, Bickel H, Sacco RL, Hofman A, Mathiesen EB, Gabriel R, Liu J, Berenson G, Kavousi M, Price JF. Normative values for carotid intima media thickness and its progression: Are they transferrable outside of their cohort of origin? Eur J Prev Cardiol. 2016 Jul;23(11):1165-73. |
4. Bonaca MP, Bhatt DL, Cohen M, Steg PG, Storey RF, Jensen EC, Magnani G, Bansilal S, Fish MP, Im K, Bengtsson O, Oude Ophuis T, Budaj A, Theroux P, Ruda M, Hamm C, Goto S, Spinar J, Nicolau JC, Kiss RG, Murphy SA, Wiviott SD, Held P, Braunwald E, Sabatine MS, PEGASUS-TIMI 54 Steering Committee and Investigators. Long-term use of ticagrelor in patients with prior myocardial infarction. N Engl J Med. 2015 May 07;372(19):1791-800. |
5. Ezhov MV, Safarova MC, Afanas'eva OI, Il'ina LN, Liakishev AA, Pokrovskiĭ SN. [High level of lipoprotein (a) as a predictor of poor long-term prognosis after coronary artery bypass surgery]. Kardiologiia. 2011;51(1):18-22. |
6. Safarova MS, Trukhacheva EP, Ezhov MV, Afanas'eva OI, Afanas'eva MI, Tripoten' MI, Liakishev AA, Pokrovskiĭ SN. [Pleiotropic effects of nicotinic acid therapy in men with coronary heart disease and elevated lipoprotein(a) levels]. Kardiologiia. 2011;51(5):9-16. |
7. Mitroshkin MG, Ezhov MV, Matchin IuG, Safarova MS, Soboleva DI, Dotsenko IuV. [Value of the spectral analysis of radiofrequency intravascular ultrasound data in the evaluation of nonsignificant coronary lesions in chronic CHD patients]. Kardiologiia. 2011;51(10):4-8. |
8. Safarova MS, Ezhov MV. Images in clinical medicine. A head shot. N Engl J Med. 2011 Dec 29;365(26):2519. |
9. Pokrovsky SN, Ezhov MV, Safarova MS, Saidova MA, Shitov VN, Afanasieva MI, Khaustov AI, Adamova IY, Afanasieva OI, Konovalov GA. Ig apheresis for the treatment of severe DCM patients. Atheroscler Suppl. 2013 Jan;14(1):213-8. |
10. Ezhov MV, Il'ina LN, Safarova MS, Afanasieva OI, Adamova IY, Atanesyan RV, Konovalov GA, Akchurin RS, Pokrovsky SN. Cascade plasma filtration during the first year after CABG in patients with hyperlipidemia refractory to statins. Atheroscler Suppl. 2013 Jan;14(1):101-5. |
11. Safarova MS, Ezhov MV, Afanasieva OI, Matchin YG, Atanesyan RV, Adamova IY, Utkina EA, Konovalov GA, Pokrovsky SN. Effect of specific lipoprotein(a) apheresis on coronary atherosclerosis regression assessed by quantitative coronary angiography. Atheroscler Suppl. 2013 Jan;14(1):93-9. |
12. Ezhov MV, Safarova MS, Afanasieva OI, Kukharchuk VV, Pokrovsky SN. Lipoprotein(a) level and apolipoprotein(a) phenotype as predictors of long-term cardiovascular outcomes after coronary artery bypass grafting. Atherosclerosis. 2014 Aug;235(2):477-82. |
13. Utkina EA, Afanas'eva OI, Adamova IIu, Ezhov MV, Safarova MS, Artem'eva NV, Adzhiev RN, Pokrovskiĭ SN. [Effect of cascade plasma filtration on spectrum of subfractions of low density lipoproteins in blood plasma of patients with ischemic heart disease]. Kardiologiia. 2014;54(4):10-5. |
14. Safarova MS, Ezhov MV, Afanasieva OI, Konovalov GA, Pokrovsky SN. Dramatic fate of a young coronary heart disease patient rescued with specific lipoprotein(a) apheresis. J Clin Apher. 2015 Jun;30(3):193-5. |
15. Safarova MS, Ezhov MV. Variance in niacin response in individuals with elevated lipoprotein(a). J Clin Lipidol. 2014;8(6):646-647. |
16. Safarova MS, Imaev TE, Lorie YY, Saidova MA, Ezhov MV. [Transcatheter Treatment of Degenerative Critical Aortic Valve Stenosis in a Patient With Severe Heart Failure and Chronic Lymphocytic Leukemia]. Kardiologiia. 2015 Jan;55(1):82-87. |
17. Safarova MS, Ezhov MV. [Evolution of Lipoprotein(a): From Biomarker to the Therapeutic Target]. Kardiologiia. 2015 Apr;55(4):71-82. |
18. Artemeva NV, Safarova MS, Ezhov MV, Afanasieva OI, Dmitrieva OA, Pokrovsky SN. Lowering of lipoprotein(a) level under niacin treatment is dependent on apolipoprotein(a) phenotype. Atheroscler Suppl. 2015 May;18:53-8. |
19. Ezhov MV, Safarova MS, Afanasieva OI, Pogorelova OA, Tripoten MI, Adamova IY, Konovalov GA, Balakhonova TV, Pokrovsky SN. Specific Lipoprotein(a) apheresis attenuates progression of carotid intima-media thickness in coronary heart disease patients with high lipoprotein(a) levels. Atheroscler Suppl. 2015 May;18:163-9. |
20. Safarova MS, Imaev TĒ, Lorie IuIu, Saidova MA, Ezhov MV. [Transcatheter treatment of degenerative critical aortic valve stenosis in a patient with severe heart failure and chronic lymphocytic leukemia]. Kardiologiia. 2015;55(1):82-7. |
21. Tagieva NR, Shakhnovich RM, Mironov VM, Yezhov MV, Matchin YG, Mitroshkin MG, Safarova MS, Shitov VN, Ruda MY. [Comparison of Atherosclerotic Lesions in Patients With Acute Myocardial Infarction and Stable Angina Pectoris Using Intravascular Ultrasound]. Kardiologiia. 2015 Jul;55(7):5-13. |
22. Sobenin IA, Zhelankin AV, Chernova EV, Kirichenko TV, Safarova MS, Sergienko IV, Doroshchuk AD, Trubinov SS, Karagodin VP, Orekhov AN. [Conventional and novel cardiovascular risk factors and predisposition to the development of atherosclerosis]. Patol Fiziol Eksp Ter. 2015;59(1):4-11. |
23. Safarova MS, Ezhov MV. [The Evolution of Views on Lipoprotein(a): From Biomarker to the Therapeutic Target]. Kardiologiia. 2015;55(4):71-82. |
24. Tagieva NR, Shakhnovich RM, Mironov YM, Yezhov MV, Matchin YG, Mitroshkin MG, Safarova MS, Shitov VN, Ruda MY. [Comparison of Atherosclerotic Lesions in Patients With Acute Myocardial Infarction and Stable Angina Pectoris Using Intravascular Ultrasound]. Kardiologiia. 2015;55(7):5-13. |
25. Safarova MS, Kullo IJ. My Approach to the Patient With Familial Hypercholesterolemia. Mayo Clin Proc. 2016 Jun;91(6):770-86. PMCID: PMC5374743 |
26. Safarova MS, Bailey KR, Kullo IJ. Association of a Family History of Coronary Heart Disease With Initiation of Statin Therapy in Individuals at Intermediate Risk: Post Hoc Analysis of a Randomized Clinical Trial. JAMA Cardiol. 2016 Jun 01;1(3):364-6. |
27. Safarova MS, Liu H, Kullo IJ. Rapid identification of familial hypercholesterolemia from electronic health records: The SEARCH study. J Clin Lipidol. 2016;10(5):1230-9. PMCID: PMC9229555 |
28. Safarova MS, Klee EW, Baudhuin LM, Winkler EM, Kluge ML, Bielinski SJ, Olson JE, Kullo IJ. Variability in assigning pathogenicity to incidental findings: insights from LDLR sequence linked to the electronic health record in 1013 individuals. Eur J Hum Genet. 2017 Apr;25(4):410-415. PMCID: PMC5386413 |
29. Kullo IJ, Safarova MS. Child-Parent Familial Hypercholesterolemia Screening in Primary Care. N Engl J Med. 2017 Feb 02;376(5):498. |
30. Burdeinaya AL, Safarova MS, Ezhov MV, Kukharchuk VV. [Degenerative Aortic Stenosis: Modern View on Development, Course, and Management]. Kardiologiia. 2016 Jun;56(6):69-74. |
31. Pokrovsky SN, Afanasieva OI, Safarova MS, Balakhonova TV, Matchin YG, Adamova IYU, Konovalov GA, Ezhov MV. Specific Lp(a) apheresis: A tool to prove lipoprotein(a) atherogenicity. Atheroscler Suppl. 2017 Nov;30:166-173. |
32. Ezhov MV, Afanasieva OI, Il'ina LN, Safarova MS, Adamova IY, Matchin YG, Konovalov GA, Akchurin RS, Pokrovsky SN. Association of lipoprotein(a) level with short- and long-term outcomes after CABG: The role of lipoprotein apheresis. Atheroscler Suppl. 2017 Nov;30:187-192. |
33. Safarova MS, Kullo IJ. Lessening the Burden of Familial Hypercholesterolemia Using Health Information Technology. Circ Res. 2018 Jan 05;122(1):26-27. PMCID: PMC5757515 |
34. Hasnie AA, Kumbamu A, Safarova MS, Caraballo PJ, Kullo IJ. A Clinical Decision Support Tool for Familial Hypercholesterolemia Based on Physician Input. Mayo Clin Proc Innov Qual Outcomes. 2018 Jun;2(2):103-112. PMCID: PMC6124345 |
35. Safarova MS, Satterfield BA, Fan X, Austin EE, Ye Z, Bastarache L, Zheng N, Ritchie MD, Borthwick KM, Williams MS, Larson EB, Scrol A, Jarvik GP, Crosslin DR, Leppig K, Rasmussen-Torvik LJ, Pendergrass SA, Sturm AC, Namjou B, Shah AS, Carroll RJ, Chung WK, Wei WQ, Feng Q, Stein CM, Roden DM, Manolio TA, Schaid DJ, Denny JC, Hebbring SJ, de Andrade M, Kullo IJ. A phenome-wide association study to discover pleiotropic effects of <i>PCSK9</i>, <i>APOB</i>, and <i>LDLR</i>. NPJ Genom Med. 2019;4:3. PMCID: PMC6370860 |
36. Safarova MS, Fan X, Austin EE, van Zuydam N, Hopewell J, Schaid DJ, Kullo IJ. Targeted Sequencing Study to Uncover Shared Genetic Susceptibility Between Peripheral Artery Disease and Coronary Heart Disease-Brief Report. Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1227-1233. PMCID: PMC6531315 |
37. Robinson JR, Carroll RJ, Bastarache L, Chen Q, Mou Z, Wei WQ, Connolly JJ, Mentch F, Sleiman P, Crane PK, Hebbring SJ, Stanaway IB, Crosslin DR, Gordon AS, Rosenthal EA, Carrell D, Hayes MG, Wei W, Petukhova L, Namjou B, Zhang G, Safarova MS, Walton NA, Still C, Bottinger EP, Loos RJF, Murphy SN, Jackson GP, Kullo IJ, Hakonarson H, Jarvik GP, Larson EB, Weng C, Roden DM, Denny JC. Association of Genetic Risk of Obesity with Postoperative Complications Using Mendelian Randomization. World J Surg. 2020 Jan;44(1):84-94. PMCID: PMC6925615 |
38. Safarova MS, Kullo IJ. Using the electronic health record for genomics research. Curr Opin Lipidol. 2020 Apr;31(2):85-93. PMCID: PMC9229554 |
39. Willeit P, Tschiderer L, Allara E, Reuber K, Seekircher L, Gao L, Liao X, Lonn E, Gerstein HC, Yusuf S, Brouwers FP, Asselbergs FW, van Gilst W, Anderssen SA, Grobbee DE, Kastelein JJP, Visseren FLJ, Ntaios G, Hatzitolios AI, Savopoulos C, Nieuwkerk PT, Stroes E, Walters M, Higgins P, Dawson J, Gresele P, Guglielmini G, Migliacci R, Ezhov M, Safarova M, Balakhonova T, Sato E, Amaha M, Nakamura T, Kapellas K, Jamieson LM, Skilton M, Blumenthal JA, Hinderliter A, Sherwood A, Smith PJ, van Agtmael MA, Reiss P, van Vonderen MGA, Kiechl S, Klingenschmid G, Sitzer M, Stehouwer CDA, Uthoff H, Zou ZY, Cunha AR, Neves MF, Witham MD, Park HW, Lee MS, Bae JH, Bernal E, Wachtell K, Kjeldsen SE, Olsen MH, Preiss D, Sattar N, Beishuizen E, Huisman MV, Espeland MA, Schmidt C, Agewall S, Ok E, Aşçi G, de Groot E, Grooteman MPC, Blankestijn PJ, Bots ML, Sweeting MJ, Thompson SG, Lorenz MW, PROG-IMT and the Proof-ATHERO Study Groups. Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100 667 Patients. Circulation. 2020 Aug 18;142(7):621-642. PMCID: PMC7115957 |
40. Rosenthal EA, Crosslin DR, Gordon AS, Carrell DS, Stanaway IB, Larson EB, Grafton J, Wei WQ, Denny JC, Feng QP, Shah AS, Sturm AC, Ritchie MD, Pacheco JA, Hakonarson H, Rasmussen-Torvik LJ, Connolly JJ, Fan X, Safarova M, Kullo IJ, Jarvik GP. Association between triglycerides, known risk SNVs and conserved rare variation in SLC25A40 in a multi-ancestry cohort. BMC Med Genomics. 2021 Jan 06;14(1):11. PMCID: PMC7789246 |
41. Saadatagah S, Jose M, Dikilitas O, Alhalabi L, Miller AA, Fan X, Olson JE, Kochan DC, Safarova M, Kullo IJ. Genetic basis of hypercholesterolemia in adults. NPJ Genom Med. 2021 Apr 14;6(1):28. PMCID: PMC8046820 |
42. Safarova MS, Ackerman MJ, Kullo IJ. A call for training programmes in cardiovascular genomics. Nat Rev Cardiol. 2021 Aug;18(8):539-540. |
43. Saadatagah S, Jose M, Dikilitas O, Alhalabi L, Miller AA, Fan X, Olson JE, Kochan DC, Safarova M, Kullo IJ. Author Correction: Genetic basis of hypercholesterolemia in adults. NPJ Genom Med. 2021 Jun 29;6(1):56. PMCID: PMC8241831 |
44. Satterfield BA, Dikilitas O, Safarova MS, Clarke SL, Tcheandjieu C, Zhu X, Bastarache L, Larson EB, Justice AE, Shang N, Rosenthal EA, Shah AS, Namjou-Khales B, Urbina EM, Wei WQ, Feng Q, Jarvik GP, Hebbring SJ, de Andrade M, Manolio TA, Assimes TL, Kullo IJ. Associations of Genetically Predicted Lp(a) (Lipoprotein [a]) Levels With Cardiovascular Traits in Individuals of European and African Ancestry. Circ Genom Precis Med. 2021 Aug;14(4):e003354. PMCID: PMC8634549 |
45. Acharya P, Dalia T, Ranka S, Sethi P, Oni OA, Safarova MS, Parashara D, Gupta K, Barua RS. The Effects of Vitamin D Supplementation and 25-Hydroxyvitamin D Levels on the Risk of Myocardial Infarction and Mortality. J Endocr Soc. 2021 Oct 01;5(10):bvab124. PMCID: PMC8358990 |
46. EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). Lancet. 2021 Nov 06;398(10312):1713-1725. |
47. Acharya P, Safarova MS, Dalia T, Bharati R, Ranka S, Vindhyal M, Jiwani S, Barua RS. Effects of Vitamin D Supplementation and 25-Hydroxyvitamin D Levels on the Risk of Atrial Fibrillation. Am J Cardiol. 2022 Jun 15;173:56-63. |
48. Safarova MS, Nugent AK, Gorby L, Dutton JA, Thompson WJ, Moriarty PM. Effect of Lipoprotein Apheresis on Progression of Carotid Intima-Media Thickness in Patients with Severe Hypercholesterolemia. Am J Cardiol. 2022 Aug 15;177:22-27. |
49. Safarova MS, Gupta K. Severe Hypertriglyceridemia as a Cause of Aortic Thrombus with Peripheral Embolic Complications. Kans J Med. 2022;15(2):298-301. PMCID: PMC9409939 |
50. Safarova MS, Kullo IJ. Lipoprotein(a) lowering and cardiovascular risk reduction by PCSK9 inhibitors. Atherosclerosis. 2022 Nov;361:30-31. |
51. Robinson JR, Carroll RJ, Bastarache L, Chen Q, Pirruccello J, Mou Z, Wei WQ, Connolly J, Mentch F, Crane PK, Hebbring SJ, Crosslin DR, Gordon AS, Rosenthal EA, Stanaway IB, Hayes MG, Wei W, Petukhova L, Namjou-Khales B, Zhang G, Safarova MS, Walton NA, Still C, Bottinger EP, Loos RJF, Murphy SN, Jackson GP, Abumrad N, Kullo IJ, Jarvik GP, Larson EB, Weng C, Roden D, Khera AV, Denny JC. Quantifying the phenome-wide disease burden of obesity using electronic health records and genomics. Obesity (Silver Spring). 2022 Dec;30(12):2477-2488. PMCID: PMC9691570 |
52. Safarova MS, Moriarty PM. Lipoprotein Apheresis: Current Recommendations for Treating Familial Hypercholesterolemia and Elevated Lipoprotein(a). Curr Atheroscler Rep. 2023 Jul;25(7):391-404. |
53. Tschiderer L, Seekircher L, Izzo R, Mancusi C, Manzi MV, Baldassarre D, Amato M, Tremoli E, Veglia F, Tuomainen TP, Kauhanen J, Voutilainen A, Iglseder B, Lind L, Rundek T, Desvarieux M, Kato A, de Groot E, Aşçi G, Ok E, Agewall S, Beulens JWJ, Byrne CD, Calder PC, Gerstein HC, Gresele P, Klingenschmid G, Nagai M, Olsen MH, Parraga G, Safarova MS, Sattar N, Skilton M, Stehouwer CDA, Uthoff H, van Agtmael MA, van der Heijden AA, Zozulińska-Ziółkiewicz DA, Park HW, Lee MS, Bae JH, Beloqui O, Landecho MF, Plichart M, Ducimetiere P, Empana JP, Bokemark L, Bergström G, Schmidt C, Castelnuovo S, Calabresi L, Norata GD, Grigore L, Catapano A, Zhao D, Wang M, Liu J, Ikram MA, Kavousi M, Bots ML, Sweeting MJ, Lorenz MW, Willeit P, Proof‐ATHERO Study Group. Association of Intima-Media Thickness Measured at the Common Carotid Artery With Incident Carotid Plaque: Individual Participant Data Meta-Analysis of 20 Prospective Studies. J Am Heart Assoc. 2023 Jun 20;12(12):e027657. PMCID: PMC10356054 |
54. Lisa Seekircher, Lena Tschiderer, Lars Lind, Maya S Safarova, Maryam Kavousi, M Arfan Ikram, Eva Lonn, Salim Yusuf, Diederick E Grobbee, John J P Kastelein, Frank L J Visseren, Matthew Walters, Jesse Dawson, Peter Higgins, Stefan Agewall, Alberico Catapano, Eric de Groot, Mark A Espeland, Gerhard Klingenschmid, Dianna Magliano, Michael H Olsen, David Preiss, Dirk Sander, Michael Skilton, Dorota A Zozulińska-Ziółkiewicz, Muriel P C Grooteman, Peter J Blankestijn, Kazuo Kitagawa, Shuhei Okazaki, Maria V Manzi, Costantino Mancusi, Raffaele Izzo, Moise Desvarieux, Tatjana Rundek, Hertzel C Gerstein, Michiel L Bots, Michael J Sweeting, Matthias W Lorenz, Peter Willeit. Intima-media thickness at the near or far wall of the common carotid artery in cardiovascular risk assessment European Heart Journal Open. European Heart Journal Open, 2023;, oead089, https://doi.org/10.1093/ehjopen/oead089 . |
55. Seekircher L, Tschiderer L, Lind L, Safarova MS, Kavousi M, Ikram MA, Lonn E, Yusuf S, Grobbee DE, Kastelein JJP, Visseren FLJ, Walters M, Dawson J, Higgins P, Agewall S, Catapano A, de Groot E, Espeland MA, Klingenschmid G, Magliano D, Olsen MH, Preiss D, Sander D, Skilton M, Zozulińska-Ziółkiewicz DA, Grooteman MPC, Blankestijn PJ, Kitagawa K, Okazaki S, Manzi MV, Mancusi C, Izzo R, Desvarieux M, Rundek T, Gerstein HC, Bots ML, Sweeting MJ, Lorenz MW, Willeit P. Intima-media thickness at the near or far wall of the common carotid artery in cardiovascular risk assessment. Eur Heart J Open. 2023 Sep;3(5):oead089. PMCID: PMC10575622 |
56. Safarova MS. Editorial: Clinical implementation of genetic scores in cardiovascular medicine. Front Cardiovasc Med. 2023;10:1292116. PMCID: PMC10704594 |
57. Hu J, Korchina V, Zouk H, Harden MV, Murdock D, Macbeth A, Harrison SM, Lennon N, Kovar C, Balasubramanian A, Zhang L, Chandanavelli G, Pasham D, Rowley R, Wiley K, Smith ME, Gordon A, Jarvik GP, Sleiman P, Kelly MA, Bland HT, Murugan M, Venner E, Boerwinkle E, eMERGE III consortium, Prows C, Mahanta L, Rehm HL, Gibbs RA, Muzny DM. Genetic sex validation for sample tracking in next-generation sequencing clinical testing. BMC Res Notes. 2024 Mar 03;17(1):62. PMCID: PMC10910835 |
58. Koschinsky ML, Bajaj A, Boffa MB, Dixon DL, Ferdinand KC, Gidding SS, Gill EA, Jacobson TA, Michos ED, Safarova MS, Soffer DE, Taub PR, Wilkinson MJ, Wilson DP, Ballantyne CM. A focused update to the 2019 NLA scientific statement on use of lipoprotein(a) in clinical practice. J Clin Lipidol. 2024;18(3):e308-e319. |
59. Safarova MS, Moriarty PM, Kullo IJ, Ballantyne CM, Gianos E. Bempedoic Acid Falls in Line. J Am Coll Cardiol. 2024 Jul 09;84(2):163-164. |
60. Safarova M, Bimal T, Soffer DE, Hirsh B, Shapiro MD, Mintz G, Cha A, Gianos E. Advances in targeting LDL cholesterol: PCSK9 inhibitors and beyond. Am J Prev Cardiol. 2024 Sep;19:100701. PMCID: PMC11278114 |
61. Haines J, Garster N, Mohananey D, Safarova MS. Diagnosis and management of arrhythmogenic cardiomyopathy: a case report. Eur Heart J Case Rep. 2024 Jul;8(7):ytae321. PMCID: PMC11276958 |
62. Safarova MS, Santos RD, Moriarty PM. Special Patient Populations: Familial Hypercholesterolemia and Other Severe Hypercholesterolemias Clinical Lipidology: A Companion to Braunwald's Heart Disease. 1 January 2023:320-335.e2. |
63. The eMERGE III consortium. Genetic sex validation for sample tracking in next-generation sequencing clinical testing. BMC Res Notes. 2024;17(1):62. PMID: 38433186. |
64. Haines J, Garster N, Mohananey D, Safarova MS. Diagnosis and management of arrhythmogenic cardiomyopathy: a case report. Eur Heart J Case Rep. 2024;8(7):ytae321. doi: 10.1093/ehjcr/ytae321 (commissioned). PMID: 39071538 |
65. The Proof-ATHERO Study Group, Intima-media thickness at the near or far wall of the common carotid artery in cardiovascular risk assessment. Eur Heart J Open. 2023; 3(5): oead089. PMID: 37840587. |
66. The Proof-ATHERO consortium. Association of intima-media thickness measured at the common-carotid artery with incident carotid plaque: Participant-level meta-analysis of 20 prospective studies. J Am Heart Assoc. 2023;12(12):e027657. PMID: 37301757. |
67. Safarova MS, Nugent AK, Gorby L, et al. Effect of Lipoprotein apheresis on progression of carotid intima-media thickness in patients with severe hypercholesterolemia. Am J Cardiol. 2022;S0002-9149(22)00520-3. PMID: 35718549. |
68. Safarova MS, Gupta K. Severe hypertriglyceridemia as a cause of aortic thrombus with peripheral embolic complications. Kans J Med. 2022; 15: 298-301. PMID: 36042836. |
69. Acharya P, Safarova MS, et al. Effects of vitamin D supplementation and 25-hydroxyvitamin D levels on the risk of atrial fibrillation. Am J Cardiol. 2022;173:56-63. PMID: 35369930. |
70. Robinson JR, Carroll RJ, Bastarache L, et al. Quantifying the phenome-wide disease burden of obesity using electronic health records and genomics. Obesity (Silver Spring). 2022;30(12):2477-2488. PMID: 36372681. |
71. Satterfield BA, Dikilitas O, Safarova MS, et al. Associations of Genetically Predicted Lipoprotein(a) Levels with Cardiovascular Traits in Individuals of European and African Ancestry. Circ Genom Precis Med. 2021;14(4):e003354. PMID: 34282949. |
72. Saadatagah S, Jose M, Dikitas O, Alhabi L, Miller A, Fan X, Olson J, Kochan D, Safarova MS, Kullo IJ. Genetic basis of hypercholesterolemia in adults. NPJ Genom Med. 2021;6(1):28. PMID: 33854068. |
73. EAS Familial Hypercholesterolaemia Studies Collaboration. Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). Lancet. 2021;398(10312):1713-1725. |
74. Rosenthal EA, Crosslin DR, Gordon AS, Carrell DS, Stanaway IB, Larson EB, Grafton J, Wei WQ, Denny JC, Feng QP, Shah A, Sturm AC, Ritchie MD, Pacheco JA, Hakonarson H, Rasmussen-Torvik L, Connolly JJ, Fan X, Safarova MS, Kullo IJ, Jarvik GP. Association between triglycerides, known risk SNVs and conserved rare variation in SLC25A40 in a multi-ancestry cohort. BMC Med Genomics. 2021; 14: 11. PMID: 33407432. |
75. Acharya P, Dalia T, Ranka S, Sethi P, Oni OA, Safarova MS, et al. The Effects of Vitamin D Supplementation and 25-Hydroxyvitamin D Levels on the Risk of Myocardial Infarction and Mortality. J Endocr Soc. 2021; 5(10): bvab124. PMID: 34396023. |
76. Safarova MS, Kullo IJ. Using the electronic health record for genomics research. Curr Opin Lipidol. 2020;31(2):85-93. PMID: 32073412. |
77. Safarova MS, Satterfield BA, Fan X, Austin EE, Ye Z, Bastarache L, Zheng N, Ritchie MD, Borthwick KM, Williams MS, Larson EB, Scrol A, Jarvik GP, Crosslin DR, Leppig K, Rasmussen-Torvik LJ, Pendergrass SA, Sturm AC, Namjou B, Shah AS, Carroll RJ, Chung WK, Wei WQ, Feng Q, Stein CM, Roden DM, Manolio TA, Schaid DJ, JC Denny, Hebbring SJ, de Andrade M, Kullo IJ. A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR. NPJ Genom Med. 2019; 4:3. PMID: 30774981. |
78. Safarova M, Fan X, Austin E, Dr. Van Zuydam N, Hopewell J, Schaid D, Kullo IJ. A targeted sequencing study to uncover shared genetic susceptibility between peripheral artery disease and coronary heart disease. Arterioscler Thromb Vasc Biol. 2019;39(6):1227-1233. PMID: 31070467. |
79. Ezhov M, Safarova M, Afanasieva O, MitroshkinM, Matchin Y, Pokrovsky S. Matrix metalloproteinase 9 as a predictor of coronary atherosclerotic plaque instability in stable coronary artery disease patients with elevated lipoprotein(a) levels. Biomolecules. 2019;9(4). PMID: 30934954. |
80. Hasnie AA, Kumbamu A, Safarova MS, Caraballo PJ, Kullo IJ. A clinical decision support tool for familial hypercholesterolemia based on physician input. Mayo Clin Proc Innov Qual Outcomes. 2018;2(2):103-112. PMID: 30225440. |
81. Safarova MS, Klee EW, Baudhuin LM, Winkler EM, Kluge ML, Bielinski SJ, Olson JE, Kullo IJ. Variability in assigning pathogenicity to incidental findings: insights from LDLR sequence linked to the electronic health record in 1013 individuals. Eur J Hum Genet. 2017;25(4):410-415. PMID: 28145427. |
82. Ezhov MV, Afanasieva OI, Il'ina LN, Safarova MS, et al. Association of lipoprotein(a) level with short- and long-term outcomes after CABG: The role of lipoprotein apheresis. Atheroscler Suppl. 2017;30:187-192. PMID: 29096836. |
83. Safarova MS, Liu H, Kullo IJ. Rapid identification of familial hypercholesterolemia from electronic health records: the SEARCH Study. J Clin Lipidol. 2016;10(5):1230-9. PMID: 27678441. |
84. Safarova MS, Bailey KR, Kullo IJ. Association of a family history of coronary heart disease with initiation of statin therapy in individuals at intermediate risk: post hoc analysis of a randomized clinical trial. JAMA Cardiol. 2016;1(3):364-6. PMID: 27438122. |
85. Ezhov MV, Safarova MS, Afanasieva OI, et al. Specific Lipoprotein(a) apheresis attenuates progression of carotid intima-media thickness in coronary heart disease patients with high lipoprotein(a) levels. Atheroscler Suppl. 2015;18:163-9. PMID: 25936321. |
86. Safarova MS, Ezhov MV, Afanasieva OI, et al. Dramatic fate of a young coronary heart disease patient rescued with specific lipoprotein(a) apheresis. J Clin Apher. 2015;30(3):193-5. PMID: 25181645. |
87. Artemeva NV, Safarova MS, Ezhov MV, et al. Lowering of lipoprotein(a) level under niacin treatment is dependent on apolipoprotein(a) phenotype. Atheroscler Suppl. 2015;18:53-8. PMID: 25936305. |
88. Safarova MS, Ezhov MV. Variance in niacin response in individuals with elevated lipoprotein(a). J Clin Lipidol. 2014;8(6):646-7. PMID: 25499949. |
89. Ezhov MV, Safarova MS, Afanasieva OI, et al. Lipoprotein(a) level and apolipoprotein(a) phenotype as predictors of long-term cardiovascular outcomes after coronary artery bypass grafting. Atherosclerosis. 2014;235(2):477-82. PMID: 24952151. |
90. Safarova MS, Ezhov MV, Afanasieva OI, et al. Effect of specific lipoprotein(a) apheresis on coronary atherosclerosis regression assessed by quantitative coronary angiography. Atheroscler Suppl. 2013;14(1):93-9. PMID: 23357149. |
91. PROG-IMT and the Proof-ATHERO Study Groups. Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100,667 Patients. Circulation. 2020;142(7)1-642. PMID: 32546049. |
92. Proof-ATHERO consortium. Normative values for carotid intima media thickness and its progression: Are they transferrable outside of their cohort of origin? Eur J Prev Cardiol. 2016;23(11):1165-73. PMID: 26746227. |
93. PEGASUS-TIMI 54 Steering Committee and Investigators. Long-term use of ticagrelor in patients with prior myocardial infarction. N Engl J Med. 2015;372(19):1791-800. PMID: 25773268. |
94. |
95. Tagieva NR, Shakhnovich RM, Mironov YM, Yezhov MV, Matchin YG, Mitroshkin MG, Safarova MS, et al. [Comparison of atherosclerotic lesions in patients with acute myocardial infarction and stable angina pectoris using intravascular ultrasound]. Kardiologiia. 2015;55(7):5-13. PMID: 26688920. |
96. Sobenin IA, Zhelankin AV, Chernova EV, Kirichenko TV, Safarova MS, et al. [Conventional and novel cardiovascular risk factors and predisposition to the development of atherosclerosis]. Patol Fiziol Eksp Ter. 2015;59(1):4-11. PMID: 26226683. |
97. Utkina EA, Afanasieva OI, Adamova IIu, Ezhov MV, Safarova MS, et al. [Effect of cascade plasma filtration on spectrum of subfractions of low density lipoproteins in blood plasma of patients with ischemic heart disease]. Kardiologiia. 2014;54(4):10-5. PMID: 25177780. |
98. Ezhov MV, Ilyina LN, Safarova MS, et al. Cascade plasma filtration during the first year after CABG in patients with hyperlipidemia refractory to statins. Atheroscler Suppl. 2013;14(1):101-5. PMID: 23357150. |
99. Pokrovsky SN, Ezhov MV, Safarova MS, et al. Ig apheresis for the treatment of severe dilated cardiomyopathy patients. Atheroscler Suppl. 2013;14(1):213-8. PMID: 23357167. |
100. Ezhov MV, Egorova LA, Safarova MS, et al. [Regression of coronary atherosclerosis in a young man with coronary heart disease following lipoprotein(a) apheresis (clinical case)]. Journal of Atherosclerosis and Dyslipidaemias. 2012;1 (12): 31-34. |
101. Safarova MS, Ezhov MV. Images in clinical medicine. A head shot. N Engl J Med. 2011;365(26):2519. PMID: 22204727. Safarova MS, Trukhacheva EP, Ezhov MV, et al. [Pleiotropic effects of nicotinic acid therapy in men with coronary heart disease and elevated lipoprotein(a) levels]. Kardiologiia. 2011;51(5):9-16. PMID: 21649590. |
102. Mitroshkin MG, Ezhov MV, Matchin IuG, Safarova MS, et al. [Value of the spectral analysis of radiofrequency intravascular ultrasound data in the evaluation of non-obstructive coronary lesions in chronic CAD patients]. Kardiologiia. 2011;51(10):4-8. PMID: 22117674. |
103. Ezhov MV, Safarova M, Afanasieva OI, et al. [High level of lipoprotein(a) as a predictor of poor long-term prognosis after coronary artery bypass surgery]. Kardiologiia. 2011;51(1):18-22. PMID: 21626797. |
104. Ezhov MV, Safarova MS, Matchin YuG, et al. [Association of high lipoprotein(a) level with coronary angiographic patency within the first year after percutaneous coronary intervention]. The Clinician. 2011;1:16-21. |
105. Safarova MS, Ezhov MV. [Effects of statin therapy in patients with chronic ischemic heart disease before and after myocardial revascularization]. Handbook of Outpatient Physician. 2011;2:33-37. |
106. Afanasieva OI, Ezhov MV, Safarova MS, et al. Lipoprotein(a) polymorphism as a risk factor for coronary and carotid atherosclerosis and its complications in women]. Journal of Cardiovascular Therapy and Prevention. 2010;6:10-16. |
107. Safarova MS, Ezhov MV, Lupanov VP, et al. [Myocardial infarction in a young man without traditional risk factors]. Journal of Cardiovascular Therapy and Prevention. 2010;5:86-90. |
108. BOOKS, CHAPTERS, REVIEWS & SCIENTIFIC STATEMENTS |
109. Safarova M, Bimal T, Soffer DE, Hirsh B, Shapiro MD, Mintz G, Cha A, Gianos E. Advances in targeting LDL cholesterol: PCSK9 inhibitors and beyond. Am J Prev Cardiol. 2024:19:100701. PMID: 39070027. |
110. Koschinsky ML, Bajaj A, Boffa MB, et al. A focused update to the 2019 NLA scientific statement on use of lipoprotein(a) in clinical practice. J Clin Lipidol. 2024:S1933-2874(24)00033-3. |
111. Safarova MS, Santos R, Moriarty PM. Special Patient Populations: Familial Hypercholesterolemia And Other Severe Hypercholesterolemias. In: Clinical Lipidology: A Companion to Braunwald's Heart Disease 3d Edition. 2023. Ed: Christie M. Ballantyne. ISBN: 978-0-323-88286-6. |
112. Safarova MS, Moriarty PM. Thrombosis, Inflammation and Lipoprotein(a): Clinical Implications. In: Lipoprotein(a). 2023. Ed.: Kostner K, Kostner GM, Toth PP. ISBN: 978-3-031-24575-6. |
113. Safarova MS, Moriarty PM. Lipoprotein Apheresis: Current Recommendations for Treating Familial Hypercholesterolemia and Elevated Lipoprotein(a) (Invited Review). Curr Atheroscler Rep. 2023;25(7):391-404. |
114. Safarova MS, de Groot E, Moriarty PM. Barbarians at The Gate: Vascular Age as an Opportunity to Timely Prevent Atherosclerotic Cardiovascular Disease. J Clin Prev Cardiol. 2023; 12(1):16-22. |
115. Safarova MS, Ackerman MJ, Kullo IJ. A call for training programmes in cardiovascular genomics. Nat Rev Cardiol. 2021;18(8):539-540. PMID: 34168341. |
116. Safarova MS, Kullo IJ. My Approach to the patient with familial hypercholesterolemia. Mayo Clin Proc. 2016;91(6):770-786. PMID: 27261867. |
117. Burdeinaya AL, Safarova MS, Ezhov MV, et al. [Degenerative aortic stenosis: modern view on development, course, and management]. Kardiologiia. 2016;56(6):69-74. Russian. PMID: 28290851. |
118. Safarova MS, Ezhov MV. [The evolution of views on Lipoprotein(a): from biomarker to the therapeutic target]. Kardiologiia. 2015;55(4):71-82. Review. Russian. PMID: 26502507. |
119. Gilyarov MYu, Safarova MS, Syrkin AL. [Stress-induced cardiomyopathy (Tako-tsubo syndrome)]. Journal of Cardiology and Cardiovascular Surgery. 2008;2:69-75. |
Editorials, Letters To Editor, Other |
1. Safarova MS, Moriarty PM, Kullo IJ, Ballantyne CM, Gianos E. Bempedoic Acid Falls in Line. J Am Coll Cardiol. 2024;84(2):163-164. PMID: 38960509. |
2. Safarova MS. Clinical implementation of genetic scores in cardiovascular medicine. Front Cardiovasc Med. 2023:10:1292116. PMID: 38075967. |
3. Safarova MS, Kullo IJ. Lipoprotein(a) lowering and cardiovascular risk reduction by PCSK9 inhibitors. Atherosclerosis. 2022;361:30-31. PMID:36042836. |
4. Safarova MS, Kullo IJ. Lessening the Burden of Familial Hypercholesterolemia Using Health Information Technology. Circ Res. 2018;122(1):26-27. PMID: 29301842. |
5. Kullo IJ, Safarova MS. Child-Parent Familial Hypercholesterolemia Screening in Primary Care. Letter to the Editor. N Engl J Med. 2017;376(5):498. PMID: 28150922. |
6. ABSTRACTS (selected out of 111 abstracts) |
7. Safarova MS, Treml A. An Uncommon Bridge to New Therapies in Severe Hypertriglyceridemia: Case Report Levels (Poster presentation at the American Society of Apheresis, 2025). |
8. Voros S, Boatwright W, Brown BO, Lozama A, Watson DS, Barnes MR, Bhatia H, Rinehart SJ, Safarova MS, Narula J. First Demonstration by Cardiac Computed Tomography that Lp(a) Drives Coronary Atherosclerosis and Calcified Plaque Development in Patients with Low ApoB and Low LDL-C Levels (Poster presentation at the American College of Cardiology Scientific Sessions, 2025). |
9. Safarova MS et al. Lipoprotein Apheresis improves HDL Proteomics and reduces the risk of Aortic Stenosis in patients with elevated Lipoprotein(a) levels and Familial Hypercholesterolemia (Moderated poster presentation at the American Heart Association Scientific Sessions, Chicago IL, 2024). |
10. Moriarty PM, Gorby L, Safarova MS, Salat D, Burns J, Moreno T, Juni JE. External counterpulsation on performance in patients with mild cognitive impairment or mild Alzheimer's disease: a randomized sham-controlled study (Moderated poster presentation at the American College of Cardiology Scientific Sessions, 2023). |
11. Safarova MS, Beaver TA, Rosamond TL, Simmons AA. Cardiobra: a novel wearable improving patient exercise tolerance and satisfaction during stress echocardiography (Poster presentation at the American College of Cardiology Scientific Sessions, 2022). |
12. Safarova MS, Gorby L, Dutton JA, Nugent A, Moriarty PM. Vascular Age in Patients With Familial Hypercholesterolemia and/or Elevated Lipoprotein(a) Treated With Lipoprotein Apheresis (Poster presentation at the American Heart Association Scientific Sessions, 2021). |
13. Dikilitas O, Satterfield BA, Safarova MS, et al. LPA Variants Are Associated With Aortic Valve Stenosis, Heart Failure and Chronic Kidney Disease. Circulation. 2020;142:A15209 (Moderated poster presentation at the American Heart Association Scientific Sessions, 2020). |