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CURRICULUM VITAE

Michael B. Dwinell PhD
Director, Professor
Department of Microbiology and Immunology

OFFICE ADDRESS:
Translational and Biomedical Research Center
8701 Watertown Plank Rd
Milwaukee, WI 53226

EDUCATION:
08/1988 - 05/1990 B.A. University of Wisconsin, Madison, WI.
09/1991 - 12/1993 M.S. University of Wisconsin, Madison, WI.
12/1993 - 12/1996 Ph.D. University of Wisconsin, Madison, WI.

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
10/1996 - 07/1999 Postdoctoral Fellow, Department of Medicine, University of
California, San Diego, La Jolla, CA.

MILITARY SERVICE:
06/1985 - 05/1992 United States Navy Reserve

FACULTY APPOINTMENTS:
07/1999 - 03/2001 Assistant Project Immunologist, Department of Medicine, University of California, San Diego, La Jolla, CA
04/2001 - 06/2007 Assistant Professor, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, WI
07/2004 - Present Professor, Graduate School, Medical College of Wisconsin, Milwaukee, WI
07/2007 - 06/2009 Associate Professor, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, WI
07/2009 - 06/2015 Associate Professor with Tenure, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, WI
07/2015 - Present Professor with Tenure, Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI
03/2017 - Present Professor, Secondary Appointment, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI

ADMINISTRATIVE APPOINTMENTS:
07/2001 - Present Member, Digestive Disease Center, Medical College of Wisconsin, Milwaukee, WI
05/2002 - Present Member, Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, Milwaukee, WI
12/2006 - Present Member, Center for Infectious Disease Research, Medical College of Wisconsin, Milwaukee, WI
09/2009 - 09/2011 Co-Director, Human Pancreatobiliary Biobank, Departments of Microbiology and Molecular Genetics, Surgery, and Pathology, Medical College of Wisconsin, Milwaukee, WI
04/2018 - Present Member, Genomic Sciences & Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI
07/2018 - Present Director, Center for Immunology, Medical College of Wisconsin, Milwaukee, WI

EDUCATIONAL ADMINISTRATIVE APPOINTMENTS:
01/2012 - Present Director, Gastrointestinal and Nutritional Pathophysiology, M2 Discovery Medical School Curriculum, Medical College of Wisconsin, Milwaukee, WI
10/2015 - Present Member, Academic Standing and Professionalism Committee, School of Medicine, Medical College of Wisconsin, Milwaukee, WI

RESEARCH ADMINISTRATIVE APPOINTMENTS:
06/2008 - Present Director, Department of Microbiology and Immunology, Bobbie Nick Voss Laboratory for Colon Cancer Research, Medical College of Wisconsin, Milwaukee, WI
09/2012 - 06/2013 Co-Leader and Investigator, Medical College of Wisconsin Cancer Center, Angiogenesis, Metastasis and the Tumor Microenvironment Research Program, Medical College of Wisconsin, Milwaukee, WI
07/2013 - 2015 Research Member, Medical College of Wisconsin Cancer Center, Cancer Biology Research Program, Medical College of Wisconsin, Milwaukee, WI
07/2019 - Present Member, Medical College of Wisconsin Cancer Center, Internal Advisory Board, Medical College of Wisconsin, Milwaukee, WI

AWARDS AND HONORS:
1994 Student Travel Grant, American Association of Veterinary Parasitologists, San Francisco, CA
1994 Marc Dresden Student Travel Award, American Society of Parasitologists, Fort Collins, CO
1995 George LaRue Award: best student oral presentation, Midwestern Conference of Parasitologists, Milwaukee, WI
1995 - 1996 Predoctoral Fellowship: National Institutes of Health, NIAID, Cellular and Molecular Parasitology Training Grant (T32 AI07414), University of Wisconsin, Madison
1996 - 1999 Postdoctoral Fellowship: National Institutes of Health, NIDDK, Gastroenterology Training Grant (T32 DK07202, University of California, San Diego, La Jolla, CA
1996 Marc Dresden Student Travel Award, American Society of Parasitologists, Tucson, AZ
1999 - 2000 Career Development Award, Crohn's and Colitis Foundation of America, New York, NY
2001 New Investigator Award, Medical College of Wisconsin Digestive Disease Center, Milwaukee, WI
2002 American Cancer Society Pilot Research Award, Medical College of Wisconsin Cancer Center, Milwaukee, WI
2003 New Faculty Grant, Research Affairs Committee, Medical College of Wisconsin, Milwaukee, WI
2003 - 2006 FIRST Award, Crohn's and Colitis Foundation of America, New York, NY
2003 - 2005 Emory T. Clarke Interdisciplinary Research Grant, Medical College of Wisconsin, Cancer Center, Milwaukee, WI
2004 Host Investigator, Mr. Charles Allen, Frontiers in Physiology, Research Teacher, the American Physiological Society, Bethesda, MD
2005 Host Investigator, Mr. Michael Aprill, Frontiers in Physiology Research Teacher, the American Physiological Society, Bethesda, MD
2007 Recipient, Laboratory Naming, Bobbie Nick Voss Charitable Funds in Colon Cancer Research, Elm Grove, WI
2008 Wisconsin Breast Cancer Showhouse Award, Cancer Center, Medical College of Wisconsin, Milwaukee, WI
2009 Outstanding Medical Student Teacher, Medical College of Wisconsin, Milwaukee, WI
2011 Outstanding Reviewer, Laboratory Investigation, Nature Publishing Group, New York, NY
2012 Outstanding Medical Student Teacher, Medical College of Wisconsin, Milwaukee, WI
2014 Outstanding Medical Student Teacher, Medical College of Wisconsin, Milwaukee, WI
2014 Excellence Award, Advancing A Healthier Wisconsin Endowment, Milwaukee, WI
2016 Outstanding Graduate Student Teacher, Medical College of Wisconsin, Milwaukee, WI
2016 Outstanding Medical Student Teacher, Medical College of Wisconsin, Milwaukee, WI
2016 Leadership for Social Inclusion and Equity Workshop, National Coalition Building Institute Campus Affiliate Program at the Medical College of Wisconsin, Milwaukee, WI
2016 Leadership Academy, Medical College of Wisconsin and the University of Wisconsin-Milwaukee Sheldon B. Lubar School of Business, Milwaukee, WI
2017 Outstanding Faculty Service Award, Medical College of Wisconsin, Milwaukee, WI
2017 Permanent Member, Tumor Microenvironment Study Section, Center for Scientific Review, National Institutes of Health, Bethesda, MD
2018 Outstanding Mentor Award, in recognition of Teaching Excellence, Graduate Student Association, Medical College of Wisconsin, Milwaukee, WI
2018 Outstanding Medical Student Teacher, Medical College of Wisconsin, Milwaukee, WI
2018 Magnanimous Mentor, Office of Research, Medical College of Wisconsin, Milwaukee, WI
2018 Mentor of the Year, Graduate School of Biomedical Sciences, Medical College of Wisconsin, Milwaukee, WI
2019 MCW Cancer Center Outstanding Basic Science Achievement Award, Medical College of Wisconsin, Milwaukee, WI

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
1992 - Present American Physiological Society (ID#00008153)
1992 - 1998 American Society of Parasitologists
1999 - Present American Gastroenterological Association (ID# 183761)
2000 - 2004 Gastroenterology Research Group
2005 - 2011 Society for Mucosal Immunology
2006 - 2008 American Association of Immunologists
2012 - Present American Association for Cancer Research (ID# 268584)
2013 - Present American Society for Biological Chemistry & Molecular Biology (ID# 33970)
2015 - 2016 American Society of Clinical Oncology

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Editorial Board
2001 - 2003 American Journal of Physiology Gastroenterology and Liver Physiology, Bethesda MD
2006 - 2009 Laboratory Investigation, New York, NY
2011 - Present Molecular Carcinogenesis, Wiley & Sons Inc, Malden, MA
2012 - Present Tissue Barriers, Landes Bioscience, Austin, TX
2013 - Present Journal of Biological Chemistry, ASBMB, Bethesda, MD
2019 - Present International Journal of Molecular Sciences, MDPI, Basel
Journal Review
2001 - Present Journal of Immunology, Bethesda, MD
2001 - Present American Journal of Physiology, Bethesda, MD
2003 - Present Experimental Parasitology, San Diego, CA
2004 - Present Journal of Biological Chemistry, Bethesda, MD
2004 - Present Gastroenterology, Elsevier, Philadelphia, PA
2004 - Present Laboratory Investigation, New York, NY
2004 - Present Inflammatory Bowel Diseases, Hoboken, NJ
2004 - Present Cytokine, Cambridge, UK
2004 - Present Cellular and Molecular Life Sciences, Basel, Switzerland
2006 - Present Cellular Microbiology, Boston, MA
2006 - Present FEBS Letters, Heidelberg, Germany
2006 - Present Nature Protocols, London, UK
2006 - Present Physiological Genomics, Bethesda, MD
2006 - Present Molecular Cancer Therapeutics, Philadelphia, PA
2006 - Present International Journal of Cancer, Heidelberg, Germany
2007 - Present Oncogene, London, UK
2008 - Present Cancer Research, Stanford, CA
2008 - Present BMC Cancer, London, UK
2008 - Present Hepatology, Hoboken, NJ
2008 - Present Cancer Science, Boston, MA
2009 - Present Gut, BMJ Publishing Group Limited, London, UK
2010 - Present Molecular Carcinogenesis, Wiley Publications, Hoboken, NJ
2011 - Present Free Radical Biology & Medicine, Elsevier, San Diego, CA
2011 - Present Molecular Biology of the Cell, Bethesda, MD
2012 - Present Apoptosis, Springer Netherlands, Amsterdam
2014 - Present Cellular & Molecular Gastroenterology & Hepatology, Elsevier
2015 - Present PloSOne, San Francisco, CA
2016 - Present Nature Communications, Nature Publishing Group
2016 - Present Scientific Reports, Nature Publishing Group
2018 - Present International Journal of Molecular Sciences, MDPI, Basel

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
1992 - 1996 Member, Department of Animal Health and Biomedical Sciences Seminar Committee, University of Wisconsin, Madison
04/2001 - 06/2018 Member, Committee on Immunology, MCW - Center for Immunology
11/2001 - Present Judge, Medical / Graduate Student Research Day, MCW-Graduate School of Biomedical Sciences
02/2002 - 03/2002 Interviewer, Interdisciplinary Program in Biomedical Sciences, MCW - Graduate School of Biomedical Sciences
07/2002 - Present Member, Digestive Disease Center Grant Review Committee, MCW - School of Medicine
08/2002 - Present Reviewer, Summer Program in Undergraduate Research (SPUR) oral presentations, MCW - Biomedical Graduate Program
03/2003 Junior Faculty Committee, Basic Science, Liaison Committee on Medical Education (LCME), MCW - School of Medicine
01/2004 - 07/2004 Member, Search Committee for Assistant/Associate Professor in Virology and Immunology, MCW - Department of Microbiology & Immunology (recruited: A. Hudson, W. Jackson)
03/2004 Curriculum and Evaluation Committee, M1/M2 Educational Objectives Retreat, MCW - School of Medicine
11/2005 Curriculum and Evaluation Committee, Medical Curriculum Objectives Retreat, MCW - School of Medicine
02/2006 - Present Chair of Course Development, Committee on Immunology, MCW - School of Medicine
02/2006 - 07/2007 Member, Search Committee for Assistant / Associate Professor in Center for Biopreparedness and infectious Disease, Microbial Pathogenesis/ Host Response, MCW - Department of Microbiology & Immunology (recruited: V. Tarakanova, C. Kristich)
08/2006 - 2009 Member, Oversight Committee, Biophotonic Imaging Core, MCW - School of Medicine
09/2006 Comprehensive Evaluation, Higher Learning Commission of the North Central Association of Colleges and Schools Accreditation Site Visit, MCW - School of Medicine
09/2006 Curriculum and Evaluation Committee, Genetics in the MCW Medical Curriculum Retreat, MCW - School of Medicine
10/2006 - 04/2012 Reviewer, American Cancer Society, Institutional Research Grant Applications, MCW - Cancer Center
04/2007 Discussant, Institutional Clinical and Translational Science Award Community Engagement Focus Group for Clinical and Translational Genetics Researchers, MCW - School of Medicine
04/2007 Convener, M1 or M2 Test Construction Committee, National Board of Medical Examiners Pilot Customized Assessment Examination, MCW - School of Medicine
04/2007 Reviewer, Reiman Post-Doctoral Fellowship Applications, MCW - Cancer Center
11/2007 Curriculum and Evaluation Committee, Integration of the Medical Curriculum Retreat, MCW - School of Medicine
01/2008 - 11/2008 Member, Search Committee, Van Dueren Endowed Chair in Breast Cancer Research, MCW - Cancer Center
09/2008 Facilitator, Medical College of Wisconsin Education Innovation Retreat, GE Healthcare Institute, MCW - School of Medicine
11/2008 - Present Reviewer, Advancing A Healthier Wisconsin Endowment - Translational Research Grant applications, Research Affairs Committee, MCW - School of Medicine
11/2008 - Present Interviewing & Admissions Committee, Medical Scientist Training Program, MCW - School of Medicine
12/2008 Reviewer, Wisconsin Breast Cancer Showcase grant applications, MCW - Cancer Center
01/2009 - 07/2011 Founder and Director, Inflammation and Cancer Cell Biology Research Group, MCW - Cancer Center
02/2009 Facilitator, Medical College of Wisconsin 2nd Education Innovation Retreat, Brookfield Suites and Convention Center, MCW - School of Medicine
02/2009 - 01/2011 Member, Steering Committee, Biospecimen Resource Facility, MCW - School of Medicine
09/2009 - 09/2011 co-Director with Dr. Doug Evans & Dr. Saul Suster, Human Pancreatobiliary Tissue Biobank Pilot Program, MCW - School of Medicine
09/2009 - 12/2014 co-Director with Dr. Bryon Johnson, Biophotonic Imaging Core, MCW - School of Medicine
10/2009 - 07/2010 Dean's Appointee, Search Committee, Chairman for the Department of Otolaryngology and Communication Sciences, MCW - School of Medicine (recruited: John Rhee, MD)
12/2009 - 11/2011 Reviewer, Clinical and Translational Science Institute Pilot Grants, MCW - School of Medicine
01/2010 - 07/2011 Liaison Committee on Medical Education (LCME) Institutional Self-Study Committee, Retreat on Institutional Setting, MCW - School of Medicine
01/2010 - 10/2010 Member, Search Committee for Assistant / Associate Professor in Innate Immunity, MCW - Department of Microbiology & Immunology (recruited: R. Robinson)
10/2010 Participant, Medical Student Curriculum Retreat, Revitalization of M3-M4 Curriculum, MCW - School of Medicine
01/2011 Reviewer, Women's Health Research Program, MCW - School of Medicine
06/2011 - 10/2012 Member, Search Committee for Assistant / Associate Professor in Cancer Cell Biology Program, MCW - Cancer Center (recruited: J. Jeong)
08/2011 New Curriculum Design Summit #1 and Summit #2, MCW - School of Medicine
11/2011 Reviewer, Novel Cancer Research Project Grant applications, MCW - Cancer Center
07/2012 National Youth Leadership Forum - Medical Forum, Demonstration "A Typical medical School Lecture", MCW - School of Medicine
01/2013 - 07/2014 Co-Chair, Inflammation and Immunology Research Strategy Group, MCW - Center for Immunology
01/2013 - 06/2014 Member, Search Committee for Assistant / Associate Professor in Cancer Cell Signaling & Metabolism Program, MCW - Cancer Center
02/2013 - 09/2014 Chair, Search Committee, Molecular Imaging in Cancer Recruitment, MCWCC Molecular Cancer Therapeutics Program (recruited: A. Joshi)
04/2013 - 06/2015 co-Leader, Inflammation and Immunology Work Group, Research Strategy Planning, MCW - School of Medicine
05/2013 Rounding with the Dean "Translational Pancreatic Cancer Research: A Template for the MCW Cancer Center", MCW - School of Medicine
06/2013 Discussant, Strategic Planning Retreat, MCW - Cancer Center
08/2013 Ad hoc, Clinical Research Seed Grant Review Committee, MCW - Cancer Center
12/2013 - Present Member, American Cancer Society, Institutional Research Grant Application Review Committee, MCW - Cancer Center
12/2013 - Present Member, Basic Research Seed Grant Review Committee, MCW - Cancer Center
03/2014 - Present Judge, MCW Mobile App Challenge, MCW - School of Medicine
04/2014 Inflammation and Immunology Research Strategy, Presentation to School of Medicine Research Council, MCW - Center for Immunology
06/2014 Inflammation and Immunology Lunch and Learn, Research Strategy Presentation to MCW Board of Trustee's, MCW - Center for Immunology
07/2014 - 11/2015 Chair, Search Committee, Cell Signaling in Cancer & Inflammation, Molecular Cancer Therapeutics Program, MCW - Cancer Center
09/2014 - 02/2017 Chair, Search Committee, Pancreatic Cancer Basic Science Researcher, MCW - Cancer Center (recruited: Gwen Lomberk & Raul Urrutia (Director, GSPMC)
05/2015 Wisconsin Breast Cancer Research and Advocacy Boot Camp, Clinical & Translational Science Institute of Southeast Wisconsin, the Medical College of Wisconsin, Froedtert, Medical College Cancer Center, and the Wisconsin Breast Cancer coalition, MCW - School of Medicine
12/2015 - 07/2016 Member, Search Committee for Chairman - Department of Dermatology, MCW - School of Medicine (recruited: Kenneth B. Gordon, MD)
08/2016 - 06/2018 Chairman, M1 / M2 Medical Course Directors Committee., MCW - School of Medicine
03/2017 - 05/2017 Member, Working Group / Steering Committee, MCW - Center for Immunology
10/2017 - 07/2018 Chair, Search Committee for Assistant / Associate Professor in Immunology, MCW - Department of Microbiology & Immunology (recruited: R. Lochhead)
05/2018 - 12/2018 Dean's Appointee, Search Committee, Director, Kern Institute for the Transformation of Medical Education (recruited: Adina Luba Kalet, MD, MPH), MCW - School of Medicine
07/2018 - Present Director, Center for Immunology, MCW
11/2018 - 06/2020 Member, Search Committee for Assistant/Associated Professor in Neuroinflammation - Neuroscience Research Center and Center for Immunology, MCW - Center for Immunology (recruited: P. Lam, & Lezi E, Department of Cell Biology, Neurobiology, & Anatomy)
05/2019 - 09/2019 Member, Search Committee for Immunotherapy Scientist - Department of Medicine, MCW - Cancer Center (recruited: Anthony Zamora, PhD)
07/2019 - 05/2020 Chair, Search Committee for Melanoma Biologist, Department of Dermatology, MCW - Cancer Center (recruited: Yu-Chieh (Jack) Wang)
10/2019 - Present Dean's Appointee, Cancer Research Building Steering Committee, MCW - School of Medicine

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
1997 - 1999 Member, Student Awards Committee, American Society of Parasitologists
01/2000 Co-Chair, Workshop on Mucosal Infection and Innate Immunity, Keystone Symposia on Molecular and Cellular Biology,, Innate and Acquired Immunity at Mucosal Surfaces, Taos, NM
2000 Reviewer, Mucosal Inflammation Section, Host Defense; American Gastroenterological Association, Digestive Disease Week 2001, Atlanta, GA
2002 - 2006 Reviewer, Immunology, Microbiology, Inflammatory Bowel Disorders section, American Gastroenterological Association, Bethesda, MD Digestive Disease Week 2003, Orlando, FL. Digestive Disease Week 2006, Los Angeles, CA
2003 - 2014 Chair, Research Forum, American Gastroenterological Association.
2003 Review Committee, US Civilian Research and Development Foundation Cooperative Grant Program
2004 - 2014 Reviewer, Intestinal Disorders Section, American Gastroenterological Association, Bethesda, MD
03/2006 Ad hoc reviewer, National Institutes of Health, NIDDK Special Emphasis Panel Review Committee, ZDK1 GRB-G (M3), Bethesda, MD
11/2006 Ad hoc grant reviewer, The Wellcome Trust, Basic Immunology and Infectious Diseases Panel, London, United Kingdom
02/2007 Ad hoc reviewer, Research Advisory Board of the St Bartholomew and the London Charitable Foundation, London, United Kingdom
11/2007 Ad hoc reviewer, Association for International Cancer Research, Madras House, St Andrews Fife, KY16 9EH
2007 - 2010 Member, Perkins Memorial Fund Committee, American Physiological Society, Bethesda, MD
12/2008 Ad hoc grant reviewer, The Wellcome Trust, Basic Immunology and Gastrointestinal Diseases Panel, London, United Kingdom
2008 - 2011 Reviewer, Senior Research Award Grant Review Committee, Crohn’s and Colitis Foundation of America, New York, NY
03/2009 - 11/2009 Ad hoc reviewer, National Institutes of Health, NIDDK Special Emphasis/Panel Review Committee, Digestive Diseases and Nutrition Mentored and Training Awards, Bethesda, MD
04/2011 Ad hoc reviewer, Individual Research Grants, The Israel Science Foundation, Jerusalem, Israel
02/2012 Ad hoc reviewer, Gastrointestinal Mucosal Pathobiology (GMPB) Study Section, National Institutes of Health, Center for Scientific Review, Bethesda, MD
03/2012 - 10/2013 Ad Hoc Reviewer, NCI Provocative Questions Special Emphasis Study Section, ZCA1 SRLB-R J1 R, Provocative Questions - Group B: Tumor Development or Recurrence, National Institutes of Health, Center for Scientific Review, Bethesda, MD
10/2012 - 06/2014 Ad Hoc Reviewer, NIDDK-DDK-C Scientific Review Group Subcommittee, Digestive Diseases and Nutrition, Mentored Awards and Training Awards, National Institutes of Health, Bethesda, MD
05/2014 Ad hoc reviewer, NCI P01 Special Emphasis Panel I, 2014/10 ZCA1 RPRB-B (O1) P meeting, Bethesda, MD
02/2015 - 06/2015 Ad hoc grant reviewer, Cancer Research UK, Science Committee, London, United Kingdom
07/2015 Ad hoc reviewer, NCI Oncological Sciences Fellowship Special Emphasis Panel/Scientific Review Group 2015/10 ZRG1 F09B-B (20) L, Internet Assisted Review
10/2015 - 06/2016 Ad hoc reviewer, NCI-I Subcommittee I - Transition to Independence Scientific Review Group, Alexandria, VA
10/2016 - 02/2017 Ad hoc reviewer, NCI Tumor Microenvironment Scientific Review Panel, Bethesda, MD
07/2017 - 06/2020 Member & Co-Chair, Tumor Microenvironment Scientific Review Panel, Center for Scientific Review, Bethesda, MD
10/2020 - Present Chair, Tumor Microenvironment Scientific Review Panel, Center for Scientific Review, Bethesda, MD

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
NIDDK Research Education Program
Source:
Research Education Project (R25 DK098104): National Institutes of Diabetes and Digestive and Kidney Diseases, and Kidney Diseases, National Institutes of Health, Bethesda, MD
Role:
Multi-PI/Multi-PD
PI:
KR Regner-contact & MB Dwinell
Dates:
09/01/2013 - 08/31/2020
Direct Funds:
$272,782
  
Title:
Targeting pancreatic cancer energy metabolism, tumor growth, and metastasis
Source:
Research Grant (U01 CA178960): National Cancer Institutes, National Institutes of Health, Bethesda, MD
Role:
Multi-PI
PI:
MB Dwinell-contact & B Kalyanaraman
Dates:
07/01/2014 - 06/30/2019
Direct Funds:
$357,583 (No Cost Extension July 1, 2019 - June 30, 2020)
  
Title:
Structural basis for chemokine function
Source:
Research Grant (R01 AI058072-11), National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD
Role:
Co-Investigator
PI:
BF Volkman
Dates:
12/01/2014 - 11/30/2019
Direct Funds:
$200,000
  
Title:
Regulation of Rap1 Prenylation and Trafficking in Breast Cancer
Source:
Research Grant (R01 CA188871): National Cancer Institutes, National stitutes of Health, Bethesda, MD
Role:
Co-Investigator
PI:
CL Williams
Dates:
04/01/2015 - 03/31/2020
Direct Funds:
$250,000
  
Title:
Sulfotyrosine-guided discovery of small molecule chemokine inhibitors
Source:
Research Grant (R01 GM097381-05A1): National Institutes of General Medical Sciences, National Institutes of Health, Bethesda, MD
Role:
Co-Investigator
PI:
BF Volkman
Dates:
04/01/2018 - 03/31/2022
Direct Funds:
$250,000
  
Title:
Translational investigation of a novel engineered variant of CCL20 as a therapeutic agent for psoriasis
Source:
Research Grant (Translational Research Grant): National Psoriasis Foundation, Portland, OR
Role:
Co-Investigator
PI:
BF Volkman
Dates:
08/01/2018 - 07/31/2020
Direct Funds:
$200,000
  
Title:
Biased chemokine receptor signaling in cancer progression
Source:
Research Grant (R01 CA226279): National Cancer Institutes, National Institutes of Health, Bethesda, MD
Role:
PI
Dates:
01/01/2019 - 12/31/2023
Direct Funds:
$1,762,360
  
Non-Peer Review
Title:
Research in colon cancer
Source:
Bobbi Nick Voss Charitable Foundation
Role:
Principal Investigator
Dates:
07/01/2007 - Present
Direct Funds:
$250,000 (Charitable Gift)
  
Title:
Medical Scientist Training Program
Source:
Institutional National Research Service Award (T32 GM080202): National Institute of General Medicine, National Institutes of Health, Bethesda, MD
Role:
Mentor Investigator
PI:
JT Barbieri
Dates:
07/01/2010 - 06/30/2020
Direct Funds:
$93,944
  
Title:
Pancreas Cancer Research Program
Source:
The Advancing a Healthier Wisconsin Endowment, Medical College of Wisconsin, Milwaukee, WI
Role:
Co-Investigator
PI:
H. Rui
Dates:
02/01/2018 - 01/31/2023
Direct Funds:
$7,313,910
  
Title:
MCW Cancer Center Director’s Promising R01 Award
Source:
Cancer Center, Medical College of Wisconsin, Milwaukee, WI
Role:
Co-PI
PI:
B. Kalyanaraman
Dates:
07/01/2019 - 06/30/2020
Direct Funds:
$50,000
  
Pending
Peer Review
Title:
IVIS Spectrum CT imager for the Medical College of Wisconsin
Source:
Small Instrument Grant (S10 OD026743-01): National Cancer Institutes, National Institutes of Health, Bethesda, MD
Role:
PI
Dates:
07/01/2019 - 06/30/2020
Direct Funds:
$599,999 (IN REVISION FOR MAY 2021)
  
Title:
Metabolic reprogramming in the melanoma tumor microenvironment
Source:
Research Grant (R01 CA253978-01) National Cancer Institutes, National Institutes of Health, Bethesda, MD
Role:
Multi-PI
PI:
MB Dwinell-contact & B Kalyanaraman
Dates:
07/01/2020 - 06/30/2025
Direct Funds:
$2,146,546 (DC Yrl $422,024)
  
Prior
Peer Review
Title:
Functional characterization and regulated expression of chemokine receptors by intestinal epithelial cells
Source:
Career Development Award, Crohn’s & Colitis Foundation of America, New York, NY
Role:
Principal Investigator
Dates:
07/01/1999 - 08/31/2000
  
Title:
Chemokine receptor expression on intestinal epithelium
Source:
Mentored Research Scientist Development Award (K01): National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD. (K01 DK002808)
Role:
Principal Investigator
Dates:
09/01/2000 - 08/31/2004
  
Title:
Chemokine receptor regulation of the epithelial barrier
Source:
Crohn’s and Colitis Foundation of America, New York, NY
Role:
Principal Investigator
Dates:
07/01/2003 - 06/30/2006
  
Title:
Chemokines in host defense to Campylobacter jejuni
Source:
Exploratory/Developmental Research Grant (R21): National Institute of Allergy and Infectious Disease National Institutes of Health, Bethesda, MD. (R21 AI055966)
Role:
Principal Investigator
Dates:
09/30/2003 - 08/31/2006
  
Title:
Epithelial CXCR4 in a mucosal communication network
Source:
Research Grant (R01): National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD. (R01 DK062066)
Role:
Principal Investigator
Dates:
04/15/2005 - 07/31/2010
  
Title:
cAMP functions as a molecular brake for epithelial restitution
Source:
Individual National Research Service Award, National Institute of Diabetes, Digestive and Kidney Diseases National Institutes of Health, Bethesda, MD. (F32 DK083209)
Role:
Sponsor
PI:
N.P. Zimmerman
Dates:
12/01/2008 - 11/30/2010
  
Title:
Epithelial CXCR4 in a mucosal communication network
Source:
Research Grant (R01): National Institutes of Diabetes and Digestive and Kidney Diseases, American Recovery and Reinvestment Act of 2009, National Institutes of Health, Bethesda, MD. (R01 DK062066-05S1)
Role:
Principal Investigator
Dates:
07/15/2009 - 05/31/2010
  
Title:
Epithelial CXCR4 in a mucosal communication network
Source:
Research Grant (R56): National Institutes of Diabetes and Digestive and Kidney Diseases, American Recovery and Reinvestment Act of 2009, National Institutes of Health, Bethesda, MD. (R56 DK062066)
Role:
Principal Investigator
Dates:
08/01/2010 - 07/31/2012
  
Title:
Therapeutic delivery of ADP-ribosylarginine hydrolase
Source:
Small Business Innovation Research Grant (Topic 91): National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
Role:
Vice President, Protein Foundry, LLC
Dates:
09/15/2015 - 03/14/2017
  
Non-Peer Review
Title:
Chemokine immunomodulation of colonic adenocarcinoma growth and differentiation
Source:
American Cancer Society Institutional Research Grant 86-004, Medical College of Wisconsin Cancer Center
Role:
Principal Investigator
Dates:
06/30/2002 - 06/29/2003
  
Title:
Chemokines in host defense to Campylobacter jejuni
Source:
Research Affairs Committee, Medical College of Wisconsin
Role:
Principal Investigator
Dates:
07/01/2003 - 07/01/2004
  
Title:
Analysis of epigenetic silencing in the immune surveillance chemokine SDF1
Source:
Emory T. Clarke Interdisciplinary Research Grant, Cancer Center, Medical College of Wisconsin
Role:
Principal Investigator
Dates:
07/01/2003 - 07/01/2004
  
Title:
Mucosal barrier defense in epithelial CXCR4 null mice
Source:
Bridge Grant, Research Affairs Committee, Medical College of Wisconsin
Role:
Principal Investigator
Dates:
01/01/2005 - 04/14/2005
  
Title:
Biophotonic Imaging Core
Source:
The Advancing a Healthier Wisconsin Endowment, Medical College of Wisconsin
Role:
Co-Investigator
PI:
Robert Truitt, PhD
Dates:
02/01/2006 - 01/31/2007
  
Title:
Epigenetic silencing of the chemokine CXCL12 in colon carcinogenesis
Source:
New Interdisciplinary Research Grant, Cancer Center, Medical College of Wisconsin
Role:
Principal Investigator
Dates:
01/01/2007 - 12/31/2008
  
Title:
Inhibition of breast and prostate cancer cell metastasis with an engineered chemokine
Source:
Wisconsin Tax Check-Off Program to Support Breast Cancer Research, Cancer Center, Medical College of Wisconsin
Role:
Co-Investigator
PI:
B. Volkman
Dates:
01/01/2008 - 02/28/2011
  
Title:
Mechanisms for autocrine SDF1 interruption of breast cancer metastasis
Source:
Wisconsin Breast Cancer Show Showhouse for a Cure Award, Cancer Center, Medical College of Wisconsin
Role:
Principal Investigator
Dates:
03/01/2008 - 02/28/2011
  
Title:
SDF dimer as an inhibitor of inflammatory bowel diseases
Source:
Medical College of Wisconsin Research Foundation
Role:
Co-Investigator
PI:
B. Volkman
Dates:
01/01/2009 - 12/31/2011
  
Title:
CXCR4 in melanoma and cutaneous squamous cell carcinoma
Source:
Postdoctoral Fellowship, Medical College of Wisconsin Cancer Center
Role:
Co-Investigator
PI:
S.T. Hwang
Dates:
01/01/2010 - 12/31/2011
  
Title:
Defining the impact of the protein kinase VRK1 on the proliferation and oncogenic potential of mammary epithelial cells
Source:
Wisconsin Breast Cancer Show Showhouse for a Cure Award, Cancer Center, Medical College of Wisconsin
Role:
Co-Investigator
PI:
P. Traktman
Dates:
07/01/2010 - 12/31/2012
  
Title:
CXCL12 treatment as a novel therapeutic paradigm for breast cancer
Source:
Wisconsin Breast Cancer Showhouse for a Cure Award, Cancer Center
Role:
Principal Investigator
Dates:
06/01/2011 - 05/31/2014
  
Title:
Mechanisms and therapeutic targeting of pancreatic cancer malignancy
Source:
Cancer Center, Medical College of Wisconsin
Role:
Multi-Principal Investigator
PI:
Dwinell & Kalyanaraman
Dates:
10/01/2011 - 09/30/2015
  
Title:
Preclinical Studies of Pancreatic Cancer Malignancy
Source:
Pre-SPORE/PPG Project Planning Seed Grant – FP9214, Medical College of Wisconsin Cancer Center and The Advancing a Healthier Wisconsin Endowment
Role:
Principal Investigator
Dates:
01/01/2016 - 12/31/2018
  
Title:
Treatment of PDAC with combined immunotherapy, Nox inhibition, and altered chemokine signaling
Source:
The Advancing a Healthier Wisconsin Endowment, Medical College of Wisconsin
Role:
Co-PI
PI:
BD Johnson
Dates:
02/01/2016 - 01/31/2018
  
Title:
Generation of conditional knockout mice with the targeted deletion of the cxcr4 gene from intestinal epithelial cells
Source:
Digestive Disease Center, Medical College of Wisconsin
Role:
Principal Investigator
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Dwinell, M.B., Mucosal chemokines and chemokine receptors, Research update seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 10/2001
Dwinell, M.B., Role of chemokines in mucosal inflammation, Research seminar, Department of Medicine Digestive Disease Center, Medical College of Wisconsin, 01/2002
Dwinell, M.B., Mucosal chemokines, Visiting Professor Research Conference for Michael Sarr, MD, Department of Surgery, Medical College of Wisconsin, 02/2002
Dwinell, M.B., Chemokines and chemokine receptors in mucosal host defense, Research update seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 11/2002
Dwinell, M.B., Chemokines and chemokine receptors in mucosal host defense, 10th Annual Wylie J. Dodds Research Lecture, Department of Medicine, Division of Gastroenterology, Digestive Diseases Center, Medical College of Wisconsin, 02/2003
Dwinell, M.B., Chemokines and chemokine receptors in host defense of the human gastrointestinal mucosa, Research seminar, Department of Biochemistry, Medical College of Wisconsin, 03/2003
Dwinell, M.B., Homeland security: Role for the intestinal epithelium in immune defense, Research update seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 12/2003
Dwinell, M.B., CXCR4 in epithelial migration, Research seminar, Cancer Center Signaling and Gene Expression Research Group, Medical College of Wisconsin, 03/2004
Dwinell, M.B., Chemokine regulation of epithelial barrier immunity: the best defense is a strong offense, Research update seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 03/2005
Dwinell, M.B., Mucosal innate immunity: the epithelium strikes back, Research update seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 02/2006
Dwinell, M.B., Chemokines at the great epithelial barrier reef, Research update seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 02/2007
Dwinell, M.B., Mucosal integrity in the balance: Defining the roles for epithelial SDF1 and CXCR4, Research update seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 03/2008
Dwinell, M.B., Couples That Work in Medicine and/or Science – How Do You Make It Work?, Medical Scientist Training Program Annual Retreat, Medical College of Wisconsin, Blue Harbor Resort & Conference Center, Sheboygan, WI, 11/2008
Dwinell, M.B., Chemokines are key regulators of tumor metastasis, Invited research seminar, Children’s Research Institute, Milwaukee, WI, 01/2009
Dwinell, M.B., Chemokines: Ubiquitous immune regulators of epithelial restitution and tumor metastasis: The yin and yang of chemokine function, Research update seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 02/2009
Dwinell, M.B., The yin and yang of chemokine function, Research seminar, Inflammation and Cancer Cell Biology Research Group, the Cancer Center, Medical college of Wisconsin, 08/2009
Dwinell, M.B., Chemokines in human gastrointestinal disease, Research update seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 11/2009
Dwinell, M.B., Roles for chemokines in inflammation and injury, Research seminar, Infectious Disease Research Conference, Department of Medicine, Division of Infectious Disease, Medical College of Wisconsin, 08/2010
Dwinell, M.B., Chemokines in cancer metastasis, Research seminar, Inflammation and Cancer Cell Biology Research Group, the Cancer Center, Medical College of Wisconsin, 09/2010
Dwinell, M.B., Shifting the paradigm: Chemokine inhibition of tumor metastasis, Invited research seminar, Committee on Immunology 2nd Annual Retreat, Blood Research Institute of Wisconsin, 10/2010
Dwinell, M.B., Epithelial chemokines and chemokine receptors in mucosal injury and cancer, Research-in-progress seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 12/2010
Dwinell, M.B., Roles for the chemokine CXCL12 in tumor malignancy, Invited research seminar, Children’s Research Institute, Milwaukee, WI, 01/2011
Dwinell, M.B., The Dwinell laboratory: A research update, Research-in-progress seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 11/2011
Dwinell, M.B., Chemokine regulation of cancer metastasis, Seminar Series, Cancer Cell Biology Research Program, the Medical College of Wisconsin Cancer Center, 12/2011
Dwinell, M.B., Roles for chemokines in malignant cancers, Cancer Cell Biology Research Forum Angiogenesis, Metastasis, & Tumor Microenvironment Research Program, Medical College of Wisconsin Cancer Center, 01/2013
Dwinell, M.B., A research update: Regulating cancer metastasis, Research-in-progress seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 02/2013
Dwinell, M.B., Chemokines in cancer: The in-and-out of malignant cell movement, Hematologic Malignancy & Transplantation Program Research Forum, Medical College of Wisconsin Cancer Center, 11/2013
Dwinell, M.B., A research update: Chemokines in cancer, Research-in-progress seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 11/2013
Dwinell, M.B., The pancreatic cancer preclinical research platform, Pancreas Club, Tumor Progression & Metastasis Program and the Department of Surgery, Medical College of Wisconsin Cancer Center, 11/2013
Dwinell, M.B., Introduction to the Signature Disease Team in Pancreatic Cancer Research and Translational Research: Preclinical and Culture Model Systems, Workshop Leader, Medical College of Wisconsin Cancer Center 2nd Annual Scientific Retreat, 06/2014
Dwinell, M.B., Anti-cancer properties of the chemokine CXCL12, 6th Annual Committee on Immunology Conference, Blood Research Institute, 09/2014
Dwinell, M.B., and B.D. Johnson, NIH Supported Team Science Opportunities: Pros & Cons for Young Investigators, Chair’s K-Club Rounds, Children’s Hospital of Wisconsin, 06/2015
Dwinell, M.B., Cancer Metastasis, Microenvironment and Mucosal Inflammation, Research-in-progress seminar, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 10/2015
Dwinell, M.B., Chemokine receptor signaling in cancer progression, Cancer Cell Biology Research Forum, Molecular Cancer Therapeutics Research Program, Medical College of Wisconsin Cancer Center, 11/2015
Dwinell, M.B., An introduction to the MCW Drug Discovery and Development Program, Surgical Oncology Research Retreat, Department of Medicine, Division of Hematology / Oncology, Medical College of Wisconsin, 07/2017
Dwinell, M.B., Targeting mitochondrial energy pathways in cancer, Milwaukee Area Mitochondriacs, Department of Biochemistry and the Medical College of Wisconsin Cancer Center and the Department of Surgery, 10/2017
Dwinell, M.B., STING agonist obliterates mouse pancreatic cancer: Is there a potential to re-ignite anti-tumor immunity in patients?, Pancreas Club, Medical College of Wisconsin Cancer Center, 05/2018
Dwinell, M.B., and M.B. Johnson, Strategies to reignite suppressed cancer immunity: STINGing pancreatic cancer, 10th Annual Immunology Conference, Medical College of Wisconsin Center for Immunology, 10/2018
Johnson, B.D., and M.B. Dwinell, Treatment of PDAC with Combined Immunotherapy, Nox Inhibition and Altered Chemokine Signaling, A Healthier Wisconsin Research and Education Program Research Symposium: Changemakers in Science, Medical College of Wisconsin, 11/2018
Dwinell, M.B., Chemokines in cancer: Can we translate into the clinic?, Department of Biophysics, Medical College of Wisconsin, 01/2019
Dwinell, M.B., Reigniting immune suppressed pancreas cancer, Department of Physiology, Medical College of Wisconsin, 03/2019
Dwinell, M.B., Activating anti-pancreatic cancer immunity, Scientific Retreat, Medical College of Wisconsin Cancer Center, 04/2019
 
Regional
Invited Speaker, Intestinal myoelectric activity in rats infected with the tapeworm Hymenolepis diminuta, Midwest Motility Meeting, 10/1993
Invited Speaker, Intestinal myoelectric alterations in tapeworm infected rats, Research update seminar, Gastroenterology Division, Veterans Administration Hospital, University of Wisconsin, Madison, WI, 09/1994
Invited Speaker, Intestinal myoelectric alterations in Hymenolepis diminuta infected rats: Correlation with aerobic bacterial populations, Midwest Motility Meeting, 04/1995
Invited Speaker, Mucosal mast cells and intestinal morphology of rats chronically infected with the tapeworm Hymenolepis diminuta, Midwest Motility Meeting, 10/1995
Invited Speaker, Intestinal transit and endogenous microflora populations in Hymenolepis diminuta infected rats., Midwest Motility Meeting, 04/1996
Lecturer, Modulation of intestinal myoelectric activity in rats infected with the tapeworm Hymenolepis diminuta., Campus wide dissertation defense seminar, Department of Animal Health and Biomedical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison WI, 10/1996
Invited Speaker, Differential expression of chemokines and chemokine receptors by human intestinal epithelial cells, Gastrointestinal Research Seminar, Department of Medicine, University of Wisconsin, Madison, WI, 10/1998
Invited Speaker, Signaling through functional chemokine receptors expressed by intestinal epithelial cells, Inflammatory Bowel Disease Research: Junior Faculty Symposium, Northwestern University Medical School, Chicago, IL, 01/2002
Invited Speaker, Mucosal host defense to Campylobacter jejuni., Midwest Microbial Pathogenesis Conference, 10th Annual meeting, University of Iowa, Iowa City, IA, 10/2003
Visiting Professor, Interruption of colorectal cancer metastasis through regulation of anoikis, Invited Research Seminar, Recent Advances in Biology Lecture Series, Lawrence University, Appleton, WI, 01/2009
Visiting Professor, Inhibiting tumor metastasis with chemokines: A tale of two graduate students, Invited Research Seminar, Interdisciplinary Program in Biomedical Sciences, Graduate School Recruitment, Ferris State University, Big Rapids, MI, 11/2011
Visiting Professor, Controlling tumor cell metastasis with chemokines, Invited Research Seminar, La Crosse BioResearch Forum, Center for Cancer and Blood Disorders, Gundersen Lutheran Medical Foundation, La Crosse, WI, 03/2012
Invited Speaker, New roles for chemotactic cytokines in pancreatic cancer, Midwest Pancreatic Cancer Scientific Research Conference, Chicago, IL, 10/2017
Invited Speaker, Innate immune activation of anti-tumor T cell responses in pancreatic cancer, 5th Annual Midwest Tumor Microenvironment Meeting, Notre Dame University, South Bend, IN, 05/2019
 
National
Invited Speaker, Modulation of intestinal myoelectric activity in rats infected with the tapeworm Hymenolepis diminuta, Research seminar, Laboratory of Mucosal Immunology, University of California, San Diego, School of Medicine, La Jolla, CA, 05/1996
Invited Speaker, Modulation of intestinal myoelectric activity in rats infected with the tapeworm Hymenolepis diminuta, Research seminar, Dartmouth Medical School, Hanover, NH, 06/1996
Invited Speaker, Role of intestinal epithelium in mucosal inflammation and host defense, Faculty candidate seminar, Department of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, MO, 06/2000
Invited Speaker, Role of intestinal epithelium in mucosal inflammation and host defense, Faculty candidate seminar, Division of Infectious Diseases, Tufts University School of Veterinary Medicine, North Grafton, MA, 06/2000
Invited Speaker, Role of intestinal epithelium in mucosal inflammation and host defense, Faculty candidate seminar, Department of Molecular Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, 07/2000
Visiting Professor, CXCR4 and SDF1 regulation of epithelial barrier integrity: the best defense is a strong offense, Invited research seminar, Mayo Clinic, Rochester, MN, 04/2005
Invited Speaker, Chemokine receptor signaling regulates intestinal epithelial cell migration and barrier defense, Research symposium speaker, FASEB 2005 Summer Conference: GI Tract XI, Innovations in GI Research and Therapy, Snowmass, CO, 08/2005
Visiting Professor, Chemokine regulation of the innate mucosal immune barrier: the best defense is a strong offense, Invited research seminar, Department of Nutritional Sciences, University of Wisconsin, Madison, WI, 01/2006
Visiting Professor, Chemokine regulation of the mucosal innate immune barrier, Invited research seminar, Department of Biological Sciences, Committee on Cell Physiology, University of Chicago, Chicago, IL, 10/2006
Visiting Professor, Shifting the paradigm: chemokine regulation of tumor metastasis, Invited research seminar, Tumor Cell Biology program, , Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, 02/2011
Visiting Professor, Controlling epithelial cell migration in inflammation and cancer, Research Seminar, The Saban Research Institute of Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, 05/2011
Visiting Professor, Controlling tumor metastasis with chemokines, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, 10/2012
Visiting Professor, Exploiting chemokine receptor signaling to regulate cancer metastasis., Purdue University Center for Cancer Research, Lafayette, IN, 10/2015
Visiting Professor, Biasing chemokine receptor functions in cancer, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, 03/2017
Visiting Professor, Biased chemokine receptor signaling & functions in cancer, Pancreatic Cancer Research Institute, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL., 03/2019
Visiting Professor, Investigating the pancreatic cancer tumor microenvironment, Department of Pharmacology, Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI., 12/2019
 
International
Visiting Professor, Role for the intestinal epithelium in host defense and mucosal inflammation, Invited research seminar, Department of Medicine B, University of Münster, Münster, GERMANY, 02/2003
Visiting Professor, Epithelial SDF1 and CXCR4: Roles in Mucosal Repair and Carcinoma Metastasis, Invited research seminar, Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, CANADA, 07/2007
Visiting Professor, Chemokine regulation of cancer metastasis, Invited research seminar, Biology Seminar Series, School of Medicine, Department of Pharmacology and Therapeutics, National University of Ireland - Galway, Galway, IRELAND, 11/2009
 

PEER REVIEWED WORKSHOPS/PRESENTATIONS:
Local
Dwinell, M.B., Is aerobic bacterial overgrowth a cause of intestinal myoelectric alterations in Hymenolepis diminuta infected rats?, Selected abstract, Annual Midwestern Conference of Parasitologists 47th Annual meeting, Milwaukee, WI, 06/1995
Roy I, N.P. Zimmerman, A.C. Mackinnon, S. Tsai, D.B. Evans, M.B. Dwinell, CXCL12 is a multifunctional tumor suppressor of pancreatic cancer, Selected abstract, Medical College of Wisconsin Cancer Center Inaugural Annual Scientific Retreat, Milwaukee, WI, 05/2013
 
National
Dwinell, M.B., and J.A. Oaks, Intestinal myoelectric activity in rats treated with the anthelminthic Praziquantel, Selected abstract, American Association of Veterinary Parasitologists 39th Annual Meeting, San Francisco, CA, 05/1994
Dwinell, M.B., and J.A. Oaks, Removal of tapeworm-associated myoelectric activity in rats infected with Hymenolepis diminuta and treated with the anthelmintic Praziquantel, Selected abstract, American Society of Parasitologists, 69th Annual Meeting, Fort Collins, CO, 07/1994
Dwinell, M.B., P. Bass, D.M. Schaefer, and J.A. Oaks, Interactions between Hymenolepis diminuta and the rat host: intestinal transit and endogenous bacterial populations, Selected abstract, American Society of Parasitologists 71st Annual Meeting, Tucson, AZ, 06/1996
Dwinell, M.B., P. Bass, and J.A. Oaks, In vivo stimulation of Hymenolepis diminuta-specific intestinal myoelectric alterations in uninfected rats, Selected abstract, American Society of Parasitologists 72nd Annual Meeting, Nashville, TN, 06/1997
Dwinell, M.B., L. Eckmann, J.D. Leopard and M.F. Kagnoff, Expression of chemokine receptors by human intestinal epithelial cells, Selected abstract, American Gastroenterological Association, Digestive Disease Week, Orlando, FL, 05/1999
Dwinell, M.B., N. Lügering, L. Eckmann, and M.F. Kagnoff, Human intestinal epithelial cells secrete interferon-inducible T lymphocyte chemoattractants, Selected abstract, Keystone Symposia on Molecular and Cellular Biology, Innate and Acquired Immunity at Mucosal Surfaces, Taos, MN, 01/2000
Dwinell, M.B., N. Lügering, L. Eckmann, and M.F. Kagnoff, Interferon (IFN)-y regulated production of chemoattractants specific for CD4+ memory T cells by human intestinal epithelial cells, Selected abstract, American Gastroenterological Association, Digestive Disease Week, New Orleans, LA., 05/2000
Heidemann, J., H. Ogawa, P. Rafiee, C. Maaser, W. Domschke, D.G. Binion and M.B. Dwinell, Mucosal angiogenesis regulated by human intestinal microvascular endothelial cell expressed CXCR4 and its cognate ligand stromal cell-derived factor-1, Selected abstract, Experimental Biology, San Diego, CA, 04/2003
Hwang S. and M.B. Dwinell, CXCL12 stimulation strengthens paracellular tightening and E-cadherin localization during intestinal epithelial restitution, Selected abstract, Digestive Disease Week, American Gastroenterological Association, New Orleans, LA, 05/2010
Agle, K.A., R.A. Vongsa, and M.B. Dwinell, CXCL12 stimulation leads to dynamic activation of laminin specific integrins promoting enterocyte adhesion and spreading, Selected abstract, Experimental Biology 2011, Washington DC, 04/2011
Zimmerman, N.P., J.R. Turner and M.B. Dwinell, cAMP abrogates intestinal epithelial restitution through PKA-dependent inhibition of actin remodeling, Selected abstract, Digestive Disease Week, American Gastroenterological Association, Chicago, IL, 05/2011
Hwang, S., and M.B. Dwinell, Chemokine signaling regulates E-cadherin localization through a ROCK and F-actin dependent mechanism during intestinal epithelial restitution, Selected abstract, Digestive Disease Week, American Gastroenterological Association, San Diego, CA, 05/2012
Moussouras, N.A., C.T. Veldkamp, B.F. Volkman, and M.B. Dwinell, Structural studies into autoinhibition by CCL21, Selected Abstract, Chemotactic Cytokines Gordon Conference: The Chemokine System at the Crossroads of Physiology and Disease, Sunday River, ME, 05/2018
 
International
Johanesen, P.A. and M.B. Dwinell, NF-kB regulates epithelial production of dendritic cell, neutrophil and T lymphocyte chemoattractants in invasive Campylobacter jejuni infection, 13th International Workshop on Campylobacter, Helicobacter and Related Organisms, Gold Coast, Queensland, AUSTRALIA, 09/2005
 

COMMITTEE SERVICE:
Medical College of Wisconsin
08/2001 - 07/2003 Member, Curriculum and Programs Committee, Graduate Studies Council, Graduate School of Biomedical Sciences
07/2004 - 06/2007 Member, Curriculum and Evaluation Committee, Faculty Council
10/2004 - 09/2006 Member, Faculty Credentials Committee, Graduate Studies Council, Graduate School of Biomedical Sciences
02/2005 - 06/2008 Dean's Appointee, Library Committee, Faculty Council
07/2005 - 06/2008 Chair, M1-M2 Subcommittee, Curriculum and Evaluation Committee, Faculty Council
12/2005 - 06/2008 Recruitment Committee, Interdisciplinary Program in Biomedical Sciences, Graduate School of Biomedical Sciences
04/2006 - 07/2006 Dean's Appointee, Educational Strategic Taskforce, Medical College of Wisconsin Strategic Planning Committee
08/2006 - 06/2011 Curriculum Committee, Interdisciplinary Program in Biomedical Sciences, Graduate School of Biomedical Sciences
07/2007 - 06/2008 Dean's Appointee, Curriculum and Evaluation Committee, Faculty Council
06/2008 - 06/2011 Chair, Recruitment Committee, Interdisciplinary Program in Biomedical Sciences, Graduate school of Biomedical Sciences
07/2009 - 06/2012 Member, Curriculum and Programs Committee, Graduate School of Biomedical Sciences
08/2009 - 01/2010 Member, Clinical Educator Planning Council, Deans Educational Innovation Advisory Committee
09/2009 - 06/2012 Member, Integration Advisory Council, Dean's Educational Innovation Advisory Committee
01/2010 - Present Member, Clinical & Translational Science Institute Clinical Scientist Mentoring Committee
07/2010 - 12/2011 Member, Discovery Curriculum Design, M1/M2 Workgroup, Medical College of Wisconsin
10/2010 - Present Member, M1/M2 Unit Directors Committee, Medical College of Wisconsin
01/2012 - 06/2018 Directors of Medical Student Education Committee Meeting
03/2013 - 12/2013 Chief's Appointee, Search Committee, MACC Fund Endowed Chair, Department of Pediatrics, Pediatric Hematology/Oncology/Bone Marrow Transplant
07/2015 - 07/2018 Chair, M1/M2 Unit Directors Committee, Medical College of Wisconsin
07/2015 - 08/2018 Member, Academic Standing Committee, Medical College of Wisconsin
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Community/Lay Public
03/2002 Advisory Board, Digestive Disease Center, Title: “Role of the Intestinal Epithelium in Mucosal Immunity”
09/2004 Advisory Board, Digestive Disease Center, Title: “Regulation of Gut Inflammation”
02/2005 Cub Scout Pack 281, Wauwatosa, WI
06/2006 - 11/2006 Laboratory Tour & Colon Cancer Research Brief, Bobbie Nick Voss Charitable Funds Board, Digestive Disease Center
07/2007 Videograph and Correspondent, Bobbie Nick Voss Charitable Funds, Medical College of Wisconsin Newsletter
09/2007 Videograph, Medical College of Wisconsin Annual Report, Graduate School of Biomedical Sciences
01/2008 Laboratory Tour & Colon Cancer Research Brief, Mr. S.D. Fisher, Digestive Disease Center Advisory Board, Medical College of Wisconsin
04/2008 Videograph Bobbie Nick Voss Charitable Funds 2008 Golf Classic
05/2008 Laboratory Tour & Research Brief, President’s Breakfast, Digestive Disease Center
09/2008 Eureka Alert, AAAS, New synthetic form of protein holds promise to stop cancer spread
09/2008 Television Interview, “Lighting Up Cancer”, Julie Feldman, WITI, Fox6 News, Milwaukee, WI
11/2008 Laboratory Tour & Research Brief, Mr. D.S. Lex, Digestive Disease Center Advisory, Medical College of Wisconsin
01/2009 President’s Breakfast, Colon Cancer Research, Digestive Disease Center and the Cancer Center, Medical College of Wisconsin
05/2009 Videograph Bobbie Nick Voss Charitable Funds, 2009 Golf Classic
09/2009 Laboratory Tour and Research Brief, Mr. Kevin Conroy, President and CEO, Exact Sciences Corp., Madison, WI
10/2009 Article, Pancreatic Tissue Bank, Pilot Biospecimen Tissue Repository, Dr. Dwinell, Dr. Suster, Dr. Evans, Medical College of Wisconsin Annual Report 2009
2009 Science Daily, Natural Protein May Halt Colorectal Cancer's Spread
09/2010 Laboratory Tour and Research Brief, Mrs. Susan Selig, Ms. Ann and Katie Heil, Medical College of Wisconsin Cancer Center
08/2011 Laboratory Videograph, Bob Uecker Introduces the Medical College of Wisconsin’s We Care Fund, Milwaukee Brewers Pregame
09/2011 VIP Laboratory Tour, Research Investigations Brief and Demonstration, Mr. J. Hovel, Department of Surgery, Medical College of Wisconsin
09/2011 Laboratory Tour and Research Brief, Mr. Brian Wroblewski, Invitee, We Care Fund Board of Trustees, Department of Surgery, Medical College of Wisconsin
11/2011 We Care Fund, Research Update, Department of Surgery, Medical College of Wisconsin
06/2013 Presentation, Cancer Research at MCW, Honoring the Lorax, The Triumph Fund, Milwaukee, WI
06/2014 Preventing Cancer Metastasis, MCW YouTube Channel (https://www.youtube.com/watch?v=vuH2hGQFSD4)
07/2014 Milwaukee Journal Sentinel, Business Section (http://www.jsonline.com/business/protein-foundry-first-start-up-in-medical-college-of-wisconsins-incubator-program-b99316416z1-268726481.html)
07/2014 WTMJ Wisconsin Weekend Morning News "For Your Health" with Steve Daniels. Recorded On – Air discussion: Starving pancreas Cancer Cells of Energy as a New Therapy (http://www.jrn.com/wtmj/shows/wisconsins-weekend-morning-news/Dr-Michael-Dwinell-267847011.html)
08/2014 Laboratory Tour, Drive Fore a Cure “Cancer Researcher for a Day”, David Castaneda (Market Development Consulting Group, Inc), Nicolas Castaneda, Raymond Juranitch, Trish Juranitch
04/2015 VIP Laboratory Tour, Research Investigations Brief and Demonstration, Mr. John Couvillon, Department of Surgery, Pancreas Cancer Research Program, Medical College of Wisconsin
05/2015 Biology of Breast Cancer, Wisconsin Breast Cancer Research and Advocacy Boot Camp, A project of the Wisconsin Breast Cancer Symposium: Innovation and Action to End Breast Cancer, CTSI of Southeastern Wisconsin, Medical College of Wisconsin
07/2015 Milwaukeean of the Week, Milwaukee Journal Sentinel, Business Blogs On Ramp (http://www.jsonline.com/blogs/business/milwaukeean-of-the-week-michael-dwinell-582884731535-315523541.html)
04/2016 Cancer Biology: The World within a Cancer Cell. Interactive lecture as part of the Conversations with Scientists: Cancer: Past, Present, and Future lecture series, Advancing a Healthier Wisconsin and the Medical College of Wisconsin Cancer Center
04/2016 Protein Stops Spread of Pancreatic Cancer, Offers Hope for Treatment for 20 Types of Cancer, (http://www.froedtert.com/blogs/ possible/chemokine-protein) Froedtert & The Medical College of Wisconsin
10/2018 Introducing your Immune System. Interactive lecture part of the Conversations with Scientists: Immunology: The Best Offense is a Good Defense lecture series, Advancing a Healthier Wisconsin and the Medical College of Wisconsin Center for Immunology
 
Medical Student Education
08/2002 - 03/2013 201-Medical Microbiology, (6 lecture contact hours, 3 small group contact hours)
08/2002 - 12/2009 201-Medical Microbiology General Laboratory, (29 laboratory contact hours)
08/2006 - 06/2013 280-M48476, Graded Elective in Translational Mucosal Immunology and Cancer Research
11/2009 - Present Physician Scientist Pathway, Mentor
06/2010 - 03/2012 Course Director, Immunology & Infection Module, 6-weeks, 72 team-based learning contact hours
04/2011 Gastrointestinal/ Nutrition Module, Small Intestine Block, Pilot Integrated Curriculum (9 TBL contact hours)
12/2011 Hematology / Neoplasia Module, Metastasis & Angiogenesis, Pilot Integrated Curriculum (3 TBL contact hours Cancer Metastasis)
01/2012 - 06/2019 Course Director, Gastrointestinal & Nutritional Pathophysiology, 3.8-weeks – oversee 80 - education hours 4 contact hours
01/2012 Hematology / Neoplasia Module, Immunology Block Director, Pilot Integrated Curriculum Team-based learning: 15 contact hours
01/2012 - 06/2014 Expert Panel Member, M2-Foundations of Pathological Processes Immunology Block Director
07/2012 - 06/2014 Expert Panel Member, M2-Endocrine and Reproductive Unit
07/2012 - 06/2014 Expert Panel Member, M2-Hematology/Lymphatic Unit
08/2012 200-Medical Pathology, (1 lecture contact hour)
02/2013 - Present Infectious Agents and Host Immunity, Immunology Block Director (coordinate 13 lecture hours) -Lecture: 8 contact hours -Small Group Team-Based Learning (TBL): 3 contact hours
04/2014 Instructor, Symptoms, Lecture: 2 contact hours
08/2014 - Present Instructor, Foundations of Pathological Processes, Lecture: 1 contact hour
07/2019 - Present Lecturer, Gastrointestinal & Nutritional Pathophysiology
 
Resident and Fellow Education
08/2003 - 06/2005 Advisory Committee, Pediatric Residency Research, Darryl Fish, MD, Children’s Hospital of Wisconsin
10/2012 - 06/2013 Scholarship Oversight Committee, Hematology/Oncology/Bone Marrow Transplant Fellowship, Sam Milanovich, MD, Department of Pediatrics, Children’s Hospital of Wisconsin
 
Continuing Medical Education
04/2006 “Mucosal Immunity”, Allergy and Immunology Grand Rounds, Children’s Hospital of Wisconsin, Medical College of Wisconsin
05/2011 Pancreas Club 45th Annual Meeting, May 6-7, 2011, Chicago, IL
 
Graduate Student Education
09/2001 - Present 05-230 - Lecturer, Current Topics in Microbiology & Immunology, Department of Microbiology and Molecular Genetics
11/2001 - 06/2007 05-242 - Lecturer, Techniques of Molecular and Cellular Biology, Department of Microbiology and Molecular Genetics
08/2002 - 05/2009 05-234 - Lecturer, Cellular and Molecular Immunology, Department of Microbiology and Molecular Genetics
08/2003 - 2010 05-236 - Lecturer, Cellular Microbiology, Department of Microbiology and Molecular Genetics
02/2006 - 12/2008 07-254 - Lecturer, Cellular Signal Transduction, Department of Pharmacology
08/2006 - 06/2007 05-242 - Course Director, Techniques of Molecular and Cellular Biology, Department of Microbiology and Molecular Genetics
06/2007 - 2009 16-242 - Co-course Director and Lecturer, Techniques of Molecular and Cellular Biology, Interdisciplinary Biomedical Graduate Program
07/2008 - 06/2017 25-251 - Lecturer, Advanced Molecular Genetics of Cancer, Department of Microbiology and Molecular Genetics
01/2009 16-300 - Lecturer, Biomedical Sciences Seminar, Interdisciplinary Biomedical Graduate Program
06/2009 - Present 25-234 - Course Director and Lecturer, Cellular and Molecular Immunology, Department of Microbiology and Molecular Genetics
08/2009 - Present 05-259 - Course Director and Lecturer, Mucosal Immunity Department of Microbiology and Molecular Genetics
10/2009 - 2011 05-260 – Lecturer, Mucosal Pathogenesis, Department of Microbiology and Molecular Genetics
12/2009 - Present 05-266, Clinical Immunology, Coordinator
12/2009 - Present 05-265, Immunological Tolerance, Coordinator
12/2009 - Present 05-263, Signaling in the Immune System, Coordinator / Lecturer
12/2009 - Present M05-264, Developmental Immunology, Coordinator
12/2009 - Present 05-262, Tumor Immunology, Coordinator
07/2010 - 09/2011 16-242 - Lecturer, Techniques of Molecular and Cellular Biology, Interdisciplinary Biomedical Graduate Program
07/2018 - Present 07-226 – Lecturer, Current Concepts in Cancer Biology, Department of Pharmacology and Toxicology (reverse classroom)
 

EXTRAMURAL TEACHING:
Community/Lay Public
04/1998 - 04/2001 University of California, San Diego, BISP-199, Instructor, Ms. Seung-eun Lee, Biology Special Studies: Independent Study, Department of Biology, University of California, San Diego, La Jolla, CA. Graduate: Master’s of Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore MD (12/2006). Current: Seung-eun Lee, MPH, U.S. Army Center for Health Promotion and Preventive Medicine, Silver Spring MD.
 
Graduate Student Education
1994 University of Wisconsin - Madison, 934-501, Teaching Assistant: Veterinary Histology, School of Veterinary Medicine, University of Wisconsin, Madison, WI.
1995 University of Wisconsin - Madison, 703-514, Laboratory Assistant: Veterinary Parasitology Laboratory, School of Veterinary Medicine, University of Wisconsin, Madison, WI.
1995 - 1996 University of Wisconsin - Madison, 970-351, Laboratory Assistant: Parasitology Laboratory, Department of Zoology, University of Wisconsin, Madison, WI.
03/1996 University of Wisconsin - Madison, 934-506, Lecturer: Veterinary Physiology-Gastrointestinal Physiology, School of Veterinary Medicine, University of Wisconsin, Madison, WI.
01/2006 University of Wisconsin - Madison, NS-881, Guest Lecturer, The Immune System in the Gastrointestinal Tract. Interdepartmental Graduate Program in Nutritional Sciences, University of Wisconsin, Madison, WI.
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
Amanda N. Cooper, M.D., Medical College of Wisconsin, 02/2006 - 12/2008, Honors Thesis, Medical Student Summer Research Program, National Cancer Institute Fellowship. 2008-2013 Residency Dermatology University of Illinois-Chicago, Chicago, IL. Current: Private Practice, Dermatology, Germantown, WI.
Eric A. Luedke, M.D., Medical College of Wisconsin, 09/2006 - 10/2006, M4-Graded Elective in Microbiology / Mucosal Immunology Research. 2007-2014, Residency General Surgery, The Ohio State University School of Medicine, Columbus, OH. 2014-2017, Clinical Instructor, General Surgery, Stanford School of Medicine, Palo Alto, CA. Current: General Surgery, Sharp Memorial Hospital, Stanford Health Care-Stanford Hospital, San Diego, CA.
Yana Thaker, M.D., Medical College of Wisconsin, 01/2011 - 09/2011, Alpha Omega Alpha Carolyn L. Kuckein Student Research Fellow. 2014-2019 Residency Gastroenterology, University of Washington. Current: General Internal Medicine, Gastroenterology, University of Washington, Seattle, WA.
Joanne P. Boisvert (Hayes), M.D., Medical College of Wisconsin, 01/2012 - 04/2015, Physician Scientist Pathway and Medical Student Summer Research Program, Honor's in Research, National Heart, Lung & Blood Institutes Fellowship. 2016-2019 Residency Family Medicine, Washington State University. Current: Family Medicine Practice, Madras, OR.
Egal I. Gorse, M.D., Medical College of Wisconsin, 01/2013 - 01/2016, Physician Scientist Pathway and Medical Student Summer Research Program, Honor's in Research, NHLBI Summer Research Program to Increase Diversity in Health-Related Research Fellow. 2016-2018 Residency Internal Medicine – Hematology / Oncology, Department of Medicine, Johns Hopkins University School of Medicine. Current: 2018- Fellowship Hematology and Medical Oncology, Emory University School of Medicine 2020 Recipient Nell W. and William Simpson Elkin Fellowship.
 
Graduate Students
Committees
Monica Mann, Medical College of Wisconsin, 04/2003 - 08/2007, PhD Awarded. Interdisciplinary Biomedical Graduate Program Department of Microbiology & Molecular Genetics and the Blood Research Institute of Wisconsin. Mentor, Bonnie Dittel, PhD
Chris Veldkamp, Medical College of Wisconsin, 06/2003 - 12/2006, PhD Awarded. Interdisciplinary Biomedical Graduate Program Department of Biochemistry. Mentor, Brian Volkman, PhD Current: Assistant Professor, University of Wisconsin-Whitewater.
M. Eric Kohler, Medical College of Wisconsin, 12/2004 - 07/2009, PhD Awarded - Medical Student Training Program, Department of Microbiology & Molecular Genetics and Department of Pediatrics. Mentor, Rimas J. Orentas, PhD
Lance Relland, Medical College of Wisconsin, 12/2004 - 03/2009, PhD Awarded. Medical Student Training Program, Department of Microbiology & Molecular Genetics and Department of Pediatrics. Mentor, Calvin A. Williams, MD, PhD
Dharini Van der Hoeven, Medical College of Wisconsin, 06/2006 - 10/2008, PhD Awarded. Interdisciplinary Biomedical Graduate Program Department of Pharmacology. Mentor, John A. Auchampach, PhD
Chrystalla Demetriadou, Medical College of Wisconsin, 08/2006 - 07/2009, MS Awarded. Interdisciplinary Biomedical Graduate Program Department of Microbiology & Molecular Genetics. Mentor, Thomas C. Zahrt, PhD
Rachel Becker, Medical College of Wisconsin, 08/2006 - 08/2009, Interdisciplinary Biomedical Graduate Program Department of Microbiology & Molecular Genetics. Mentor, Dara Frank, PhD
James Schuman, Medical College of Wisconsin, 10/2006 - 05/2010, PhD Awarded. Interdisciplinary Biomedical Graduate Program Department of Microbiology & Molecular Genetics and the Blood Research Institute of Wisconsin. Mentor, Demin Wang, PhD
Kathryn Marshall, Medical College of Wisconsin, 05/2007 - 03/2009, PhD Awarded. Interdisciplinary Biomedical Graduate Program, Department of Cell Biology, Neurobiology & Anatomy. Mentor, Allan Mayer, MD, PhD
Alec (Oleg) Vishnevsky, Medical College of Wisconsin, 03/2008 - 10/2008, Medical Student Training Program, Department of Microbiology & Molecular Genetics and Department of Pediatrics. Mentor, William Grossmann, MD, PhD
Alicia Castonguay, Medical College of Wisconsin, 07/2008 - 04/2011, PhD Awarded. Interdisciplinary Biomedical Graduate Program Department of Biochemistry. Mentor, Nancy Dahms, PhD
Katherine Schmalzer, Medical College of Wisconsin, 10/2008 - 03/2012, PhD Awarded. Interdisciplinary Biomedical Graduate Program Department of Microbiology & Molecular Genetics. Mentor, Dara Frank, PhD
Erica Treslley-Schmitt, Medical College of Wisconsin, 01/2009 - 12/2012, PhD Awarded. Medical Student Training Program, Department of Microbiology & Molecular Genetics and Department of Pediatrics. Mentor, Calvin A. Williams, MD, PhD
Sreemanti Basu, Medical College of Wisconsin, 01/2009 - 01/2012, PhD Awarded. Interdisciplinary Biomedical Graduate Program Department of Microbiology & Molecular Genetics and the Blood Research Institute of Wisconsin. Mentor, Bonnie Dittel, PhD
Tyce Kearl, Medical College of Wisconsin, 02/2009 - 08/2012, PhD Awarded. Medical Student Training Program, Department of Microbiology & Molecular Genetics and Department of Pediatrics. Mentor, Bryon Johnson, PhD
Ty Molitor, Medical College of Wisconsin, 02/2009 - 04/2012, PhD Awarded. Interdisciplinary Biomedical Graduate Program, Department of Microbiology & Molecular Genetics. Mentor, Paula Traktman, PhD
Krista E. Asp, Medical College of Wisconsin, 04/2009 - 11/2010, Medical Student Training Program, Department of Microbiology & Molecular Genetics. Mentor, Thomas Zahrt, PhD
Adam Gastonguay, Medical College of Wisconsin, 05/2009 - 05/2012, PhD Awarded. Interdisciplinary Biomedical Graduate Program Department of Pharmacology & Toxicology. Mentor, Carol Williams, PhD
Amy J. Beres, Medical College of Wisconsin, 08/2009 - 10/2012, – PhD Awarded. Interdisciplinary Biomedical Graduate Program Department of Microbiology & Molecular Genetics and Department of Medicine. Mentor, William Drobyski, MD
Joshua J. Ziarek, Medical College of Wisconsin, 10/2009 - 11/2011, PhD Awarded. Interdisciplinary Biomedical Graduate Program Department of Biochemistry. Mentor: Brian Volkman, PhD. Current: Postdoctoral Research, Harvard Univ.
Andrew D. Hauser, Medical College of Wisconsin, 06/2011 - 05/2013, PhD Awarded. Interdisciplinary Biomedical Graduate Program Department of Pharmacology & Toxicology. Mentor: Carol Williams, PhD. Current: Postdoctoral Associate, New York University, Mentor: Dafna Bar-Sagi, MD
Ya Zhuo, Medical College of Wisconsin, 09/2011 - 03/2014, PhD Awarded. Interdisciplinary Biomedical Graduate Program, Department of Biophysics. Mentor: Candice Klug, PhD.
Nathan J. Schuld, Medical College of Wisconsin, 01/2012 - 01/2014, – PhD Awarded. Interdisciplinary Biomedical Graduate Program, Department of Pharmacology & Toxicology. Mentor: Carol Williams, PhD. Current: Postdoctoral Fellow, University of Minnesota. Mentor: Deborah Ferrington, PhD
Anthony E. Getschman, Medical College of Wisconsin, 05/2012 - 05/2016, PhD Awarded. Interdisciplinary Biomedical Graduate Program, Department of Biochemistry. Mentor: Brian Volkman, PhD
Amy Rymaszewski, Medical College of Wisconsin, 08/2012 - 01/2017, PhD Awarded. Interdisciplinary Biomedical Graduate Program, Department of Pharmacology & Toxicology. Mentor: Haris Vikis, PhD / Carol L. Williams, PhD
Matthew Forsberg, Medical College of Wisconsin, 02/2013 - 07/2017, – PhD Awarded. Interdisciplinary Biomedical Graduate Program, Department of Department of Microbiology & Molecular Genetics. Mentor: Yi-Guang Chen, PhD
Jonathan Jeschke, Medical College of Wisconsin, 02/2013 - 06/2017, PhD Awarded. Medical Student Training Program, Department of Microbiology & Molecular Genetics and Department of Pediatrics. Mentor, Calvin A. Williams, MD, PhD
Aye Mon, Medical College of Wisconsin, 02/2013 - 06/2015, Interdisciplinary Biomedical Graduate Program, Department of Department of Microbiology & Molecular Genetics. Mentor: Paula Traktman, PhD. student moved with her advisor to Medical University of South Carolina
Kathleen Dixon, Medical College of Wisconsin, 12/2014 - 2019, - PhD Awarded. Interdisciplinary Biomedical Graduate Program, Department of Department of Microbiology & Immunology. Mentor: Subramaniam Malarkannan, PhD
Vanessa (Cheng-Yin) Yuan, Medical College of Wisconsin, 03/2015 - Present, Interdisciplinary Biomedical Graduate Program, Department of Department of Microbiology & Molecular Genetics. Mentor: William Drobyski, MD
Sarah Riutta, Medical College of Wisconsin, 04/2015 - 05/2018, PhD Awarded. Interdisciplinary Biomedical Graduate Program, Department of Biochemistry. Mentor, Brian Volkman, PhD
Andrew Kleist, Medical College of Wisconsin, 04/2015 - 04/2019, PhD Awarded. Medical Student Training Program, Ruth L. Kirschstein National Research Service Fellow (CA196040), National Cancer Institute, NIH, Department of Biochemistry. Mentor, Brian Volkman, PhD
Monica Thomas, Medical College of Wisconsin, 04/2015 - 05/2018, PhD Awarded. Medical Student Training Program, Ruth L. Kirschstein National Research Service Fellow (F30 HL134253), National Heart, Lung, and Blood Institute, NIH, Department of Biochemistry. Mentor, Brian Volkman, PhD.
Peter Volberding, Medical College of Wisconsin, 11/2017 - 05/2020, PhD Awarded. Interdisciplinary Biomedical Graduate Program, Department of Department of Microbiology & Immunology. Mentor: Weiquo Cui, PhD
Paytsar Topchyan, Medical College of Wisconsin, 12/2018 - Present, Medical Student Training Program, Department of Microbiology & Immunology. Mentor: Weiguo Cui, PhD
Ammar Alsheikh, Medical College of Wisconsin, 12/2018 - 05/2020, PhD Awarded. Physiology Graduate Program, Department of Physiology. Mentor: David Mattson, PhD
Kyler Crawford, Medical College of Wisconsin, 12/2019 - Present, Medical Student Training Program, Department of Biochemistry. Mentor: Brian F. Volkman, PhD
Joseph Crecelius, Medical College of Wisconsin, 08/2020 - Present, Interdisciplinary Biomedical Graduate Program, Department of Biochemistry. Mentor: Adriano Marchese, PhD
Jian Shen, Medical College of Wisconsin, 08/2020 - Present, Interdisciplinary Biomedical Graduate Program, Department of Microbiology & Immunology. Mentor, Weiguo Cui, PhD.
PhD Students Advised
Michael K. Wendt, Ph.D., Medical College of Wisconsin, 06/2003 - 10/2007 Interdisciplinary Biomedical Graduate Program, Department of Microbiology & Molecular Genetics, Recipient, Doctor of Philosophy Outstanding Dissertation Award. Postdoc: Research Scientist, American Cancer Society Postdoctoral Fellow, NCI Temin K99/R00 Award recipient, Case Western Reserve University, Cleveland, OH. Mentor: William Schiemann, Ph.D. Current (01/2014- ): Associate Professor, Purdue University, Lafayette, IN
Rebecca A. Vongsa (nee Moyer), Ph.D., Medical College of Wisconsin, 06/2004 - 12/2008 Interdisciplinary Biomedical Graduate Program, Department of Microbiology & Molecular Genetics, Current (01/2009- ): Scientist-III, Kimberly-Clark Corp., Skin Health and Infection Control Health Care Division, Appleton, WI.
Luke J. Drury, Ph.D., Medical College of Wisconsin, 06/2006 - 05/2011 Interdisciplinary Biomedical Graduate Program, Department of Microbiology & Molecular Genetics, Postdoc: NHLBI Postdoctoral Fellow, University of Iowa Holden Comprehensive Cancer Center Mentor: Adam Dupuy, Ph.D. Current (11/2013 -): Human Molecular Geneticist, Prevention Genetics, Marshfield Clinic, Marshfield, WI.
Soonyean Hwang, Ph.D., Medical College of Wisconsin, 06/2007 - 05/2012 Interdisciplinary Biomedical Graduate Program, Department of Microbiology & Molecular Genetics, Current: Postdoctoral Fellow, Dana-Farber Cancer Institute, Harvard Cancer Center, Mentor: Martin E. Hemler, PhD.
Kimberle A. Agle, Ph.D., Medical College of Wisconsin, 06/2008 - 04/2012 Interdisciplinary Biomedical Graduate Program, Department of Microbiology & Molecular Genetics, Current: Scientist-II, Immucor, Inc, Waukesha, WI.
Hong Guan, Ph.D., Medical College of Wisconsin, 01/2009 - 10/2009 Interdisciplinary Biomedical Graduate Program, Department of Microbiology & Molecular Genetics, Current: Doctoral Candidate, Department of Chemistry and Biochemistry, University of South Carolina.
Ishan Roy, M.D., Ph.D., Medical College of Wisconsin, 10/2009 - 06/2014 Medical Scientist Training Program, Department of Microbiology & Molecular Genetics, Current (2016): Clinical Instructor & Chief Resident Physician; Department of Physical Medicine & Rehabilitation, Northwestern University/Shirley Ryan Ability Lab.
Jonathan D. Van Wickle, Medical College of Wisconsin, 01/2015 - 06/2016 Medical Scientist Training Program, Department of Microbiology & Immunology, Current: Resident, Radiation Oncology, University of Iowa.
Natasha A. Moussouras, Ph.D., Medical College of Wisconsin, 04/2015 - 06/2020 Medical Scientist Training Program, Ruth L. Kirschstein National Research Service Fellow (F30 CA210587), National Cancer Institute, NIH, Department of Microbiology & Immunology
Emily Vonderhaar, Ph.D., Medical College of Wisconsin, 02/2016 - 06/2020 Medical Scientist Training Program, CTSA TL1 Mentored Clinical Research Training Fellow (TR001437), National Center for Advancing Translational Sciences, NIH, Department of Microbiology & Immunology
Mahmoud Abu Eid, Medical College of Wisconsin, 05/2018 - Present Interdisciplinary Biomedical Graduate Program, Department of Microbiology & Immunology
 
Postdoctoral Students
Jan Heidemann, MD, Medical College of Wisconsin, 09/2001 - 08/2002, Postdoctoral Scientist, Co-mentor with David G. Binion MD. Current: Assoc. Dr. med, Director, Department of Gastroenterology, University Hospital Bielefeld, GERMANY.
Priscilla A. Johanesen, PhD, Medical College of Wisconsin, 05/2002 - 02/2007, Postdoctoral Fellow, Mucosal Immunology, Department of Microbiology & Molecular Genetics Current: Associate Professor (Tenured), Deputy Head of Department (Education), Department of Microbiology, Monash University, Melbourne, AUSTRALIA.
Jennifer M. Boardman (nee Smith), PhD, Medical College of Wisconsin, 05/2002 - 07/2004, , Postdoctoral Fellow, Mucosal Immunology. Current: Assistant Dean for Academic Affairs for the School of Graduate Studies, Associate Professor, Microbiology and Immunology, Department of Basic Sciences, Geisinger Commonwealth School of Medicine, Scranton, PA.
W. Martin Floer, MD, Medical College of Wisconsin, 07/2006 - 06/2007, Postdoctoral Scientist, Co-mentor with David G. Binion MD. Current: Department of Gastroenterology, HELIOS Albert-Schweitzer-Hospital Northeim, GERMANY.
Noah P. Zimmerman, PhD, Medical College of Wisconsin, 08/2006 - 11/2010, NIDDK Postdoctoral Fellow, Mucosal Immunology. 02/2012-12/2012. Instructor, Departments of Medicine and Microbiology and Molecular Genetics, the Medical College of Wisconsin Cancer Center. Current: Research Manager, Arm and Hammer, Waukesha, WI
 
Residents
Sridevi Ramalingam, MD, Medical College of Wisconsin, 06/2014 - 06/2015 Research Mentor, Froedtert Lutheran Hospital, Department of Medicine, Division of Hematology & Oncology
Andres Yarur, MD, Medical College of Wisconsin, 02/2017 - 06/2018 Research Mentor, Froedtert Lutheran Hospital, Department of Medicine, Division of Gastroenterology & Hepatology
Michael Halyko, MD, Medical College of Wisconsin, 07/2019 - Present Research Mentors, Children's Hospital of Wisconsin, Department of Pediatrics, Division of Hematology & Oncology,
 
Faculty
Haris Vikis, PhD, Medical College of Wisconsin, 12/2011 - 07/2014 Assistant Professor, Department of Pharmacology, Medical College of Wisconsin Cancer Center
Jay Tichelaar, PhD, Medical College of Wisconsin, 02/2012 - 07/2014 Assistant Professor, Department of Pharmacology, Medical College of Wisconsin Cancer Center
Laura Kresty, PhD, Medical College of Wisconsin, 08/2013 - 06/2017 Associate Professor, Department of Medicine, Division of Hematology & Oncology,
Anna Huppler, MD, Medical College of Wisconsin, 01/2014 - Present Assistant Professor, Department of Pediatrics, Division of Infectious Disease
Scott R Welak, MD, Medical College of Wisconsin, 08/2014 - Present Assistant Professor, Department of Pediatrics, Division of Neonatology
Michael James, PhD, Medical College of Wisconsin, 08/2014 - Present Assistant Professor, Department of Surgery, Division of Surgical Oncology
Robert Lochhead, PhD, Medical College of Wisconsin, 08/2018 - Present, Assistant Professor, Department of Microbiology & Immunology,
Jacek Ziekonka, PhD, Medical College of Wisconsin, 01/2019 - Present Assistant Professor, Department of Biophysics
Brian Craig, MD, Medical College of Wisconsin, 09/2020 - Present, Assistant Professor, Department of Surgery, Division of Pediatric Surgery, Children’s Wisconsin, Medical College of Wisconsin
 
Clinical Staff
Christy Barrios, PhD, Medical College of Wisconsin, 12/2014 - 06/2015 Research Scientist-I, Department of Microbiology & Molecular Genetics,
Kathleen Boyle, PhD, Medical College of Wisconsin, 07/2015 - 02/2019 Research Scientist-II, Department of Microbiology & Immunology. Current: Assistant Professor, Mt. Mary University, Milwaukee, WI
 

EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
High School Students
N Ruth Marks, 06/2009 - 08/2009 Supervisor, Student Hourly, Summer Undergraduate Trainee, American Recovery and Reinvestment Act of 2009 Undergraduate Fellow Brookfield Academy High School, Class of 2010. Current: Medical Student, Stanford University School of Medicine.
Olivia Gorman, Nicolet High School Science and Engineering Fair, Class of 2016, 01/2013 - 04/2013 Research Mentor
Katya Opryshchenko, 01/2013 - 04/2013 Research Mentor, Nicolet High School Science and Engineering Fair, Class of 2016
Hajira Fuad, University School of Milwaukee, Class of 2017, 06/2016 - 06/2017 Research Mentor
Vaishnavi Gundamrai, 12/2017 - 02/2019 Research Mentor, Brookfield Academy, Students Understanding Principles of Research Education through Medicine, Engineering, and Science (SUPREMES) program and CTSI 500 Stars Internship Program
Jada Mitchell, 06/2018 - 08/2019 Research Mentor, CTSI 500 Stars Internship Program, Current: Ohio University
 
Undergraduate Students
Arash Izadpanah, 07/1999 - 06/2000 Supervisor, Independent Study Project Committee Member, University of California, San Diego, School of Medicine, Howard Hughes Medical Institute Medical Student Fellow. Current: Dermatologist, Scripp’s Clinic Carmel Valley, San Diego. http://www.scripps.org/Doctors.aspx?ID=9130
Lisa Guerrettaz, 04/2000 - 04/2001 Supervisor/Mentor, Work-Study Undergraduate Student, University of California, San Diego School of Medicine PhD awarded 2009, University of Colorado. Postdoctoral Fellow, Genomics Institute, Novartis Research Foundation, San Diego, CA. Current: Scientist II, Fate Therapeutics, Inc., San Diego, CA.
Michael K. Wendt, 05/2001 - 08/2001 Preceptor, Summer Program for Undergraduate Research, St. Norbert College
Scott Teper, 07/2001 - 09/2001 Supervisor, Student Hourly, University of Chicago. Graduate: Master’s of Public Health (2004), Epidemiology and Public Health, Yale University, New Haven, CT. Current: Senior Associate, Homeland Security and Emergency Management Practice ICF International, Washington DC
Eric A Luedke, 05/2002 - 08/2002 Preceptor, Summer Program for Undergraduate Research, Marquette University. Graduate: MD, Medical College of Wisconsin (2007) Surgical Resident, Department of Surgery, The Ohio State University College of Medicine, Columbus, OH. Current: General Surgeon, Sharp HealthCare, Stanford Hospital & Clinics, San Diego, CA.
Jeffrey M Gehl, 05/2003 - 08/2003 Preceptor, Summer Program for Undergraduate Research, University of Wisconsin. Graduate: MD, Rush Medical College (2009) Current: Staff Physician, Internal Medicine & Pediatrics, Medical College of Wisconsin, Children’s Hospital of Wisconsin, Milwaukee, WI.
Kristen Aicher, 05/2006 - 08/2006 Preceptor, Summer Program for Undergraduate Research, Carroll College.
Cayla Thompson (nee Lillge), 05/2009 - 08/2009 Preceptor, Summer Program for Undergraduate Research and Fellow of the American Recovery and Reinvestment Act of 2009, University of Wisconsin, Platteville. PhD (2017) Medical College of Wisconsin, Milwaukee, WI. Current (2017-): Scientist, Cellular Dynamics International, Madison, WI.
 
Graduate Students
Committees
Cynthia Opansky, 05/2006 - 05/2007, MS Awarded, Thesis Committee, University of Wisconsin-Milwaukee, Clinical Laboratory Science Program Mentor: Robert S. Burlage, PhD Current: Research Scientist, Blood Research Institute, Milwaukee, WI.
Erica Lowthers, 04/2007 - 07/2007, External Examiner, PhD Awarded, Department of Pharmacology, Faculty of Graduate Studies, Dalhousie University, CANADA. Mentor: Jonathan Blay, PhD
Angela O’Gorman, 09/2009 - 02/2010, External Examiner, PhD Awarded, Department of Pharmacology & Therapeutics, National University of Ireland, Galway, IRELAND. Mentor, Laurence J. Egan, MD
 

PROGRAMMATIC DEVELOPMENTS:
Educational Programs
Student
09/13/2007 - 09/01/2009 M1-2 Curriculum Integration Action Plan, Learning Resource Subcommittee, Medical College of Wisconsin
02/19/2008 - 02/20/2009 M1 NBME Customized Examination, Learning Resource Subcommittee, Medical College of Wisconsin
01/01/2015 - 12/31/2015 Self-Directed Integrated Medical Immunology & Inflammation Curriculum
Faculty
05/01/2005 - 07/31/2007 A Strategic Planning Retreat for Identifying and Addressing the Hidden Professionalism Curriculum, Learning Resource Subcommittee, Medical College of Wisconsin
03/01/2006 - 11/01/2009 Integrating CEC Strategic Themes Across the Curriculum: Phase-1, Learning Resource Subcommittee, Medical College of Wisconsin
 
 
 
 

COMMUNITY SERVICE ACTIVITIES:
08/2003 Speaker, Research Alliance Reception, Crohn’s and Colitis Foundation of America Wisconsin Chapter, David Barnett Gallery, Milwaukee, WI
02/2004 Speaker, February Family Conference, Laughter and Medicine 2004, Crohn’s and Colitis Foundation of America Wisconsin Chapter, Wisconsin Dells, WI
09/2004 Speaker, Research Alliance Reception, Crohn’s and Colitis Foundation of America Wisconsin Chapter, Allan Bradley Clocktower, Milwaukee, WI
07/2005 Speaker, American Cancer Society, Relay for Life 2005, Fort Atkinson, WI
09/2005 Discussant, Research Alliance Reception, Crohn’s and Colitis Foundation of America Wisconsin Chapter, Allan Bradley Clocktower, Milwaukee, WI
09/2006 Discussant, Research Alliance Reception, Crohn’s and Colitis Foundation of America Wisconsin Chapter, Allan Bradley Clocktower, Milwaukee, WI
07/2007 Invited Guest, Bobbie Nick Voss Golf Classic, North Hills Country Club, Menomonee Falls, WI
06/2008 Invited Guest, Bobbie Nick Voss Golf Classic, North Hills Country Club, Menomonee Falls, WI
06/2011 Invited Guest, 2011 Wisconsin Breast Cancer Showhouse Preview, Milwaukee, WI
06/2011 Invited Guest, Bobbie Nick Voss Golf Classic, North Hills Country Club, Menomonee Falls, WI
07/2011 Invited Guest, Annual Emmie S. Mikulay Tee Up for a Cure, the Wisconsin Breast Cancer Showhouse, Milwaukee, WI
10/2011 Guest, Wisconsin Breast Cancer Showhouse annual Recognition Dinner, River Hills, WI
01/2012 Guest Speaker, Delafield Chamber of Commerce and the Wisconsin Breast Cancer Showhouse Pink Tie Gala, Delafield, WI
06/2012 Invited Guest, Annual Emmie S. Mikulay Tee Up for a Cure, the Wisconsin Breast Cancer Showhouse, Milwaukee, WI
07/2012 Invited Guest, MCW Alumni Golf Outing
05/2013 Invited Guest, 2011 Wisconsin Breast Cancer Showhouse Preview, Milwaukee, WI
06/2013 Triumph Funding, "Metastasis — Hope Peeks Out From Behind Its Dark Shadows", (http://thetriumphfund.wordpress.com/musings-5/)
07/2013 Invited Guest, Annual Emmie S. Mikulay Tee Up for a Cure, the Wisconsin Breast Cancer Showhouse, Milwaukee, WI
07/2014 Invited Guest, Annual Emmie S. Mikulay Tee Up for a Cure, the Wisconsin Breast Cancer Showhouse, Milwaukee, WI
10/2014 Turning the Table, The Medical College of Wisconsin Cancer Center is Committed to Curing Pancreatic Cancer. Article By Deborah R. Huso, pg 140, October 2014 usairwaysmag.com
07/2018 “Let’s Crush Cancer – Bella’s Story” MCW Cancer Center signature fundraising campaign.
 

ENTREPRENUERSHIP:
04/2014 Co-Founder, Vice President, and Managing Member, Protein Foundry LLC, Milwaukee, WI
03/2020 Co-Founder, Managing Member, Xlock Biosciences, LLC, Milwaukee, WI

PATENTS AND INTELLECTUAL PROPERTY:
06/2005 MCWRF #1371 “The Chemokine Stromal Cell-Derived Factor-1 (SDF1)/CXCL12 in therapeutic treatment of carcinoma” U.S. Patent 8,404,640 “Method of Diagnosing and Treating Colon Cancer – Dwinell et al” Issued: March 26, 2013
08/2005 MCWRF#1377 “The chemokine receptor CXCR4 and its chemokine stromal cell-derived factor-1 (SDF1)/CXCL12 in therapeutic repair of the mucosal epithelium” Disclosed
11/2006 MCWRF #1524 “Establishment and maintenance of a novel and unique intestinal epithelial cell line expressing human Paneth cell antimicrobial peptide human alpha defensins” Disclosed.
11/2006 MCWRF #1506 “Chemokine Receptor CXCR4-Knockout Mouse” Disclosed
04/2008 MCWRF #1574 “Floxed CXCL12 Mice” Disclosed.
09/2015 MCWRF #C1890 "Chemokine Variants as Immune Stimulants" Disclosed. Patent Application Pending


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Dwinell, M.B., P. Bass, and J.A. Oaks. 1994. Intestinal myoelectric alterations in rats chronically infected with the tapeworm Hymenolepis diminuta. American Journal of Physiology 267 (Gastrointestinal & Liver Physiology 30): G851-G858. PMID: 7977747
2. Dwinell, M.B., P. Bass, and J.A. Oaks. 1995. Praziquantel treatment normalizes intestinal myoelectric alterations associated with Hymenolepis diminuta infected rats. Journal of Parasitology, 81(6): 979-984. PMID: 8544075
3. Rowell, D.L., L. Eckmann, M.B. Dwinell, S.P. Carpenter, J.L. Raucy, S-K. Yang, and M.F. Kagnoff. 1997. Human hepatocytes express a regulated array of proinflammatory cytokines following agonist stimulation or bacterial invasion. American Journal of Physiology 273 (Gastrointestinal & Liver Physiology 36): G322-G332. PMID: 9277410
4. Dwinell, M.B., P. Bass, D.M. Schaefer, and J.A. Oaks. 1997. Tapeworm infection decreases intestinal transit and enteric aerobic bacterial populations. American Journal of Physiology 273 (Gastrointestinal & Liver Physiology 36): G480-G485. PMID: 9277428
5. Dwinell, M.B., R.M. Wise, P. Bass, and J.A. Oaks. 1998. Hymenolepis diminuta: Mucosal mastocytosis and intestinal smooth muscle hypertrophy occurs in tapeworm-infected rats. (Cover Art) Experimental Parasitology, 89: 92-102. PMID: 9603494
6. Dwinell, M.B., P. Bass, and J.A. Oaks. 1998. Hymenolepis diminuta-fractions but not previous tapeworm infection stimulate intestinal myoelectric alterations in vivo in the rat. Journal of Parasitology, 84(4): 673-670. PMID: 9714192
7. Dwinell, M.B., L. Eckmann, J.D. Leopard, N.M. Varki, and M.F. Kagnoff. 1999. Chemokine receptor expression on human intestinal epithelial cells. (Cover Commentary) Gastroenterology, 117: 359-367. PMID: 10419917
8. Merendino, N., M.B. Dwinell, N.M. Varki, L. Eckmann, and M.F. Kagnoff. 1999. Human intestinal epithelial cells express receptors for platelet activating factor. American Journal of Physiology 277 (Gastrointestinal & Liver Physiology 40): G810-G818. PMID: 10516147
9. Eckmann, L., J.R. Smith, M.P. Housley, M.B. Dwinell, and M.F. Kagnoff. 2000. Analysis by high-density cDNA arrays of altered gene expression in human intestinal epithelial cells in response to infection with the invasive enteric bacteria Salmonella. Journal of Biological Chemistry, 275: 14084-14094. PMID: 10799483
10. Dwinell, M.B., N. Lügering, L. Eckmann, and M.F. Kagnoff. 2001. Regulated production of interferon-inducible T cell chemoattractants by human intestinal epithelial cells. Gastroenterology, 120: 49-59. PMID: 11208713 Commentary: Luster AD (2001) Chemokines regulate lymphocyte homing to the intestinal mucosa. Gastroenterology. 120(1):291-4. PMID: 11208738
11. Izadpanah, A., M.B. Dwinell, L. Eckmann, N.M. Varki, and M.F. Kagnoff. 2001. Regulated production MIP-3/CCL20 production by human intestinal epithelium: Mechanism for modulating mucosal immunity. American Journal of Physiology Gastrointestinal and Liver Physiology, 280: G710-G719. PMID: 11254498
12. Berin, M.C., M.B. Dwinell, L. Eckmann, and M.F. Kagnoff. 2001. Production of MDC/CCL22 by human intestinal epithelial cells. American Journal of Physiology Gastrointestinal and Liver Physiology, 280: G1217-G1226. PMID: 11352815
13. Heidemann, J., H. Ogawa, M.B. Dwinell, P. Rafiee, C. Maaser, H.R. Gockel, M.F. Otterson, N. Lügering, W. Domschke, and D.G. Binion. 2003. Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2. Journal of Biological Chemistry, 278: 8508-8515. Epub 2002 Dec 20. PMID: 12496258
14. Rafiee, P., H. Ogawa, J. Heidemann, M.S. Li, M. Aslam, T.H. Lamirand, P.J. Fisher, S.J. Graewin, M.B. Dwinell, C.P. Johnson, R. Shaker, D.G. Binion. 2003. Isolation and characterization of human esophageal microvascular endothelial cells: Mechanisms of inflammatory activation. American Journal of Physiology Gastrointestinal and Liver Physiology, 285: G1277-1292. Epub 2003 Aug 14. PMID: 12919942
15. Dwinell, M.B., H. Ogawa, K.E. Barrett, and M.F. Kagnoff. 2004. Stromal cell-derived factor-1/CXCL12 regulates cyclic AMP production and ion transport in intestinal epithelial cells via CXCR4. American Journal of Physiology Gastrointestinal and Liver Physiology, 286: G844-G850. Epub 2003 Dec 18. PMID: 14684377
16. Heidemann, J., H. Ogawa, P. Rafiee, N. Lügering, C. Maaser, W. Domschke, D.G. Binion and M.B. Dwinell. 2004. Mucosal angiogenesis regulation by CXCR4 and its ligand CXCL12 expressed by human intestinal microvascular endothelial cells. American Journal of Physiology Gastrointestinal and Liver Physiology, 286: G1059-G1068. Epub 2004 Feb 05. PMID: 14764445
17. Smith, J.M., P.A. Johanesen, M.K. Wendt, D.G. Binion, and M.B. Dwinell. 2005. CXCL12 activation of CXCR4 regulates mucosal host defense through stimulation of epithelial cell migration and promotion of barrier integrity. American Journal of Physiology Gastrointestinal and Liver Physiology, 288: G316-G326. Epub 2004 Sep 09. PMID: 15358596
18. Yang, C., H. Ogawa H., M.B. Dwinell, D.F. McCole, L. Eckmann, and M.F. Kagnoff. 2005. Chemokine receptor CCR6 transduces signals that activate p130Cas and alter cAMP-stimulated ion transport in human intestinal epithelial cells. American Journal of Physiology Cell Physiology, 288: C321-C328. Epub 2004 Oct 13. PMID: 15483227
19. Wendt, M.K., P.A. Johanesen, N. Kang-Decker, D.G. Binion, V. Shah, and M.B. Dwinell. 2006. Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. Oncogene, 25:4986-4997. Epub 2006 Mar 27. PMID: 16568088
20. Johanesen, P.A. and M.B. Dwinell. 2006. Flagellin-independent regulation of chemokine host defense in Campylobacter jejuni-infected intestinal epithelium. Infection and Immunity, 74: 3437-3447. PMID: 16714574 / PMCID: PMC1479283
21. Moyer, R.A., M.K. Wendt, P.A. Johanesen, J.R. Turner, and M.B. Dwinell. 2007. Rho activation regulates CXCL12 chemokine stimulated actin rearrangement and restitution in model intestinal epithelia. (Cover Art) Laboratory Investigation, 87:807-817. Epub 2007 Jun 18. PMID: 17572689 / PMCID: PMC2693067
22. Wendt, M.K., A.N. Cooper, and M.B. Dwinell. 2008. Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells. Oncogene, 27:1461-1471. Epub 2007 Sept 3. PMID: 17724466
23. Wendt, M.K., L.J. Drury, R.A. Vongsa, and M.B. Dwinell. 2008. Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells. Gastroenterology, 135:508-517. Epub 2008 May 15. PMID: 18558091 / PMCID: PMC2583344
24. Vongsa, R.A., N.P. Zimmerman, and M.B. Dwinell. 2009. CCR6 regulation of the actin cytoskeleton orchestrates human beta-defensin-2 and CCL20-mediated restitution of colonic epithelial cells. Journal of Biological Chemistry, 284: 10034-10045. Epub 2009 Feb 20. PMID: 19233848 / PMCID: PMC2665058
25. Agle, K.A., R.A. Vongsa, and M.B. Dwinell. 2010. Calcium mobilization triggered by the chemokine CXCL12 regulates migration in wounded intestinal epithelial monolayers. Journal of Biological Chemistry, 285: 16066–16075. Epub 2010 Mar 26. PMID: 20348095 / PMCID: PMC2871475
26. Drury, L.J., M.K. Wendt, and M.B. Dwinell. 2010. CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through Bim-mediated intrinsic apoptosis. PLoSOne 5(9): e12895. Epub 2010 Sept 22. PMID: 20877573 / PMCID: PMC2943927
27. Zimmerman, N.P., S. Faherty, R.A. Vongsa, N.H. Salzman, and M.B. Dwinell. 2011. Targeted intestinal epithelial deletion of the chemokine receptor CXCR4 reveals important roles for extracellular-regulated kinase-1/2 in restitution. Laboratory Investigation, 91:1040-1055. Epub 2011 May 2. PMID: 21537329 / PMCID: PMC3167207
28. Agle, K.A., R.A. Vongsa, and M.B. Dwinell. 2011. Chemokine stimulation promotes enterocyte migration through laminin-specific integrins. American Journal of Physiology Gastrointestinal and Liver Physiology, 301(6):G968-980. Epub 2011 Sep 15. PMID: 21921288 / PMCID: PMC3233784
29. Drury L.J., J.J. Ziarek, S. Gravel, C.T. Veldkamp, T. Takekoshi, S.T. Hwang, N. Heveker, B.F. Volkman, and M.B. Dwinell. 2011. Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways. Proceedings of the National Academy of Sciences, USA, 108:17655-17660. Epub 2011 Oct 11. PMID: 21990345 / PMCID: PMC3203819.
30. Zimmerman, N.P., S.N. Kumar, J.R. Turner, M.B. Dwinell. 2011. Cyclic AMP dysregulates intestinal epithelial cell restitution through PKA and RhoA. Inflammatory Bowel Diseases, Jun;18(6):1081-91. Epub 2011 Oct 12. doi:10.1002/ibd.21898. PMID: 21993975 / PMCID: PMC3167207
31. Hwang, S., N.P. Zimmerman, K.A. Agle, J.R. Turner, S.N. Kumar, and M.B. Dwinell. 2012. E-cadherin is critical for collective sheet migration and is regulated by the chemokine CXCL12 during restitution. Journal of Biological Chemistry, 287: 22227-22240. Epub 2012 May 1 doi:10.1074/jbc.M112.367979 PMID: 22549778 / PMCID: PMC3381184
32. Takekoshi, T., X. Wu, H. Mitsui, Y. Tada, M .C. Kao, S. Sato, M.B. Dwinell, S.T. Hwang. 2013. CXCR4 negatively regulates keratinocyte proliferation in IL-23-mediated psoriasiform dermatitis. Journal of Investigative Dermatology,133:2530–2537. Epub 2013 Mar 25. doi: 10.1038/jid.2013.151. PMID: 23528817 / PMCID: PMC3972890 Commentary: Bollag, W.B. and W.D. Hill (2013) CXCR4 in Epidermal Keratinocytes: Crosstalk within the Skin. Journal of Investigative Dermatology, 133, 2505–2508. doi:10.1038/jid.2013.271. PMID: 24129780
33. Ntantie, E, P. Gonyo, E. Lorimer, D. McAllister, B. Kalyanaraman, M.B. Dwinell, J. Auchampach, and C.L. Williams. 2013. An adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering. (Cover Art) Science Signaling, 6:ra39. Epub 2013 May28 doi: 10.1126/scisignal.2003374. PMID: 23716716 / PMCID: PMC4278376 Commentary: Linden J (2013) Adenosine promotes tumor metastasis. PMID: 23716715
34. Cheng, G., J. Zielonka, D.M. McAllister, A.C. Mackinnon, J. Joseph, M.B. Dwinell, and B. Kalyanaraman. 2013. Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promotes cell death. BMC Cancer. 13:285. doi: 10.1186/1471-2407-13-285. PMID: 23764021 / PMCID: PMC3686663
35. Zimmerman, N.P., I. Roy, A.D. Hauser, J.M. Wilson, C.L. Williams, and M.B. Dwinell. 2015. Cyclic AMP levels regulate the migration and invasion potential of human pancreatic cancer cells. Molecular Carcinogenesis. 54(3):203-215. doi: 10.1002/mc.22091. PMID: PMID: 24115212 / PMCID: PMC4087083
36. Wang, L., S. Cossette, K. Rarick, J. Gershan, M.B. Dwinell, D.A. Harder, and R. Ramchandran. 2013. Astrocytes directly influence tumor cell invasion and metastasis in vivo. PLoSOne. 8(12):e80933. Epub. 2013 Dec 4;doi: 10.1371/pone.0080933. PMID: 24324647 / PMCID: PMC3851470
37. Roy, I., N.P. Zimmerman, A.C. Mackinnon, S. Tsai, D.B. Evans, and M.B. Dwinell. 2014. CXCL12 chemokine expression suppresses human pancreatic cancer growth and metastasis. PLoSOne. 9(3): e90400. Epub. 2014 Mar 4 doi: 10.1371/pone.0090400. PMID: 24594697 / PMCID: PMC3942415
38. Cheng, G., J. Zielonka, D. McAllister, S. Tsai, M.B. Dwinell, and B. Kalyanaraman. 2014. Profiling and targeting of cellular bioenergetics: Inhibition of pancreatic cancer cell proliferation. British Journal of Cancer. 111:85-93. Epub 2014 May 27 doi: 10.1038/bjc.2014.272. PMID:24867695 / PMCID: PMC4090735
39. Flister M.J., B.T. Endres, N. Rudemiller, A.B. Sarkis, S. Santarriaga, A. Lemke, I. Roy, A.M. Geurts, C. Moreno, S. Ran, S-W. Tsaih, J. De Pons, D.F. Carlson, W. Tan, S.C. Fahrenkrug, Z. Lazarova, J. Lazar, P.E. North, P.S. LaViolette, M.B. Dwinell, J.D. Shull, and H.J. Jacob. 2014. CXM - a new tool for mapping breast cancer risk in the tumor microenvironment. Cancer Research. 74(22):6419-5429. Epub 2014 Aug 29 doi: 10.1158/0008-5472.CAN-13-3212. PMID: 25172839 / PMCID: PMC4247541
40. Cheng, G., J. Zielonka, D. McAllister, M. Hardy, O. Ouari, J. Joseph, M.B. Dwinell, and B. Kalyanaraman. 2015. Anti-proliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism. Cancer Letters, 365(1):96-106. Epub 2015 doi: 10.1016/j.canlet.2015.05.016, PMID: 26004344 / PMCID: PMC4476640.
41. Qi, X-M, N. Yin, S. Ma, A. Lepp, J. Tang, W. Jing, B. Johnson, M.B. Dwinell, C.R. Chitambar, and G. Chen. 2015. p38γ MAPK is a therapeutic target for triple-negative breast cancer by stimulation of cancer stem-like cell expansion. Stem Cells, 365(1):96-106. Jun 15. doi: 10.1002/stem.2068. PMID: 26077647 / PMCID: PMC4476640.
42. Roy, I., D. McAllister, E. Gorse, K. Dixon, C.T. Piper, N.P. Zimmerman, A.E. Getschman, S. Tsai, D.D. Engle, D.B. Evans, B.F. Volkman, B. Kalyanaraman, and M.B. Dwinell. 2015. Chemokine biased agonism regulates pancreatic cancer migration and metastasis through bioenergetic signaling. Cancer Research, 75:3529-3542. Epub Sept2 2015 doi: 10.1158/0008-5472.CAN-14-2645. PMID: 26330165 / PMCID: PMC4560104.
43. Hillmer, R.E., J.P. Boisvert, M.J. Cucciare, M.B. Dwinell* and M. Joksimovic*. 2015. Generation and characterization of mice harboring a conditional CXCL12 allele. International Journal of Developmental Biology, 59:205-209. doi: 10.1387/ijdb.140348mj. PMID: 26505253 / PMCID: In process. * = co-corresponding senior authors
44. Cheng, G., J. Zielonka, O. Ouari, M. Lopez, D. McAllister, K. Boyle, C.S. Barrios, J. J. Weber, B.D. Johnson, M. Hardy, M.B. Dwinell and B. Kalyanaraman. 2016. Mitochondria-targeted analogs of metformin exhibit enhanced antiproliferative and radiosensitizing effects in pancreatic cancer cells. Cancer Research, 76:3904-3915. Epub 2016 May 23 doi: 10.1158/0008-5472.CAN-15-2534. PMID: 27216187 / PMCID: PMC4930686.
45. Palen K., J. Weber, M.B. Dwinell, B. Johnson, R. Ramchandran and J. Gershan. 2016. E-cadherin re-expression shows in vivo evidence for mesenchymal to epithelial transition in clonal metastatic breast tumor cells. Oncotarget, 7:43363-43375. Epub 2016 May 30. doi: 10.18632/oncotarget.9715. PMID: 27270319 / PMCID: PMC5190029.
46. Roy, I, K.A. Boyle, E.P. Vonderhaar, N.P. Zimmerman, E. Gorse, A.C. Mackinnon, R.F. Hwang, J. Franco-Barraza, E. Cukierman, S. Tsai, D.B. Evans, and M.B. Dwinell. 2017. Cancer cell chemokines direct chemotaxis of activated stellate cells in pancreatic ductal adenocarcinoma. (Cover Art) Laboratory Investigation, 97:302–317. Epub 2017 Jan 16. doi: 10.1038/labinvest.2016.146. PMID: 28092365 / PMCID: PMC5334280.
47. Ziarek J.J., A.B. Kleist, N. London, B. Raveh, N. Montpas, J. Bonneterre, G. St-Onge, C.J. DiCosmo-Ponticello, C.A. Koplinski, I. Roy, B. Stephens, S. Thelen, C.T. Veldkamp, F.D. Coffman, M.C. Cohen, M.B. Dwinell, M. Thelen, F.C. Peterson, N. Heveker, and B.F. Volkman. 2017. Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation. Science Signaling. 10(471). EPub 2017Mar 21;10(471). pii: eaah5756. doi: 10.1126/scisignal.aah5756. PMID: 28325822 / PMCID: PMC5648539.
48. Phillips A.J., D. Taleski, C.A. Koplinski, A.E. Getschman, N.A. Moussouras, A.M. Richard, F.C. Peterson, M.B. DWINELL, B.F. Volkman, R.J. Payne, and C.T. Veldkamp. 2017. CCR7 sulfotyrosine enhances CCL21 binding. International Journal of Molecular Sciences, 18(9), 1857; EPub 2017Aug24; doi:10.3390/ijms18091857. PMID: 28841151 / PMCID: PMC5618506.
49. Moussouras, N.A., A.E. Getschman, E.R. Lackner, C.T. Veldkamp, M.B. Dwinell, and B.F. Volkman. 2017. Differences in sulfotyrosine binding amongst CXCR1 and CXCR2 chemokine ligands. International Journal of Molecular Sciences, 18(9):1894. EPub 2017 Sep 3. doi: 10.3390/ijms18091894. PMID: 28869519 / PMCID: PMC5618543.
50. Tsai, S., L. McOlash, K. Palen, B.D. Johnson, C. Duris, Q. Yang, M.B. Dwinell, B. Hunt, D.B. Evans, J. Gershan, and M.A. James. 2018. Development of primary human pancreatic tumor organoids, matched stromal and immune cells and 3D tumor microenvironment models. BMC Cancer, 18:335. EPub. 2018 Mar27. doi: 10.1186/s12885-018-4238-4. PMID: 29587663 / PMCID: PMC5870823
51. Wesley, E., G. Xin, D. McAllister, S. Malarkannan, D.K. Newman, M.B. Dwinell, W. Cui, B.D. Johnson, and M.J. Riese. 2018. Diacylglyerol kinase ζ and Casitas b-lineage proto-oncogene b deficient mice have similar functional outcomes in T cells but DGKζ-deficient mice have increased T cell activation and tumor clearance. ImmunoHorizons, 2(4):107-118. doi: 10.4049/immunohorizons.1700055. PMID: 30027154 / PMCID: PMC6048965
52. Boyle, K.A., J. Van Wickle, R. B. Hill, A. Marchese, B. Kalyanaraman, and M.B. Dwinell. 2018. Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation. Journal of Biological Chemistry, 293(38):14891-14904 2018 Aug 7. doi: 10.1074/jbc.RA117.001469. PMID: 30087121 / PMCID: PMC6153299
53. Tsai, S., L. McOlash, S. Jia, J. Zhang, P. Simpson, M. Kaldunski, M. Aldakkak, J. Grewal, K. Palen, M.B. Dwinell, B.D. Johnson, A.C. Mackinnon, M.J. Hessner, and J.A. Gershan. 2019. A serum-induced transcriptome and serum cytokine signature analyzed from pre-treatment serum obtained at diagnosis correlates with the development of early pancreatic ductal adenocarcinoma metastasis. Cancer Epidemiology, Biomarkers & Prevention, 28(4):680-689. 2018 Dec 7. doi: 10.1158/1055-9965.EPI-18-0813. PMID: 30530849 / PMCID: PMC6545232
54. Jing, W., D. McAllister, E.P. Vonderhaar, K. Palen, M.J. Riese, J. Gershan, B.D. Johnson, and M.B. Dwinell. 2019. STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models. Journal for ImmunoTherapy of Cancer, 7(1):115. 2019 Apr 29. 10.1186/s40425-019-0573-5. PMID: 31036082 / PMCID: PMC6489306
55. Cheng, G., J. Zielonka, M. Hardy, O. Ouari, C.R. Chitambar, M.B. Dwinell, and B. Kalyanaraman. 2019. Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators. Oncotarget, 10(37):3518-3532. doi: 10.18632/oncotarget.26943. eCollection 2019 May 28. PMID: 31191823 PMCID: PMC6544408
56. Cheng, G., J. Pan, R. Podsiadly, J. Zielonka, A. Garces, L.G.D. Machado, B. Bennett, D. McAllister, M.B. Dwinell, M. You, and B. Kalyanaraman. 2020. Increased formation of reactive oxygen species during tumor growth: Ex vivo low-temperature EPR and in vivo bioluminescence analyses. Free Radical Biology & Medicine, 147:167-174. doi: 10.1016/j.freeradbiomed.2019.12.020. PMID: 31874251/ PMCID: PMC6948008
57. Moussouras, N.A., G. Hjortø, F.C. Peterson, M. Szpakowska, A. Chevigne, M.M. Rosenkilde, B.F. Volkman, and M.B. Dwinell. 2020. Structural features of an extended C-terminal tail modulate function of the chemokine CCL21. Biochemistry, 59(13):1338-1350. doi: 10.1021/acs.biochem.0c00047. eCollection 2020 Mar17. PMID: 32182428 / PMCID: In Progress
58. Wang, F., X-M Qi, R. Wertz, M. Mortensen, C. Hagen, J. Evans, Y. Sheinin, M. James, P. Liu, S. Tsai, J. Thomas, A.C. Mackinnon, M.B. Dwinell, C.R. Myers, R. Bartrons L. Fu, and G. Chen. 2020. p38gamma MAPK is essential for aerobic glycolysis and pancreatic tumorigenesis. Cancer Research, 80(16):3251-3264. 10.1158/0008-5472.CAN-19-3281. PMID: 32580961 / PMCID: In Progress.
59. Cheng, G., M. Hardy, J. Zielonka, K. Weh, M. Zielonka, K.A. Boyle, M. Abu Eid, D. McAllister, B. Bennett, L.A. Kresty, M.B. Dwinell, B. Kalyanaraman. 2020. Mitochondria-Targeted Magnolol Inhibits OXPHOS, Proliferation, and Tumor Growth via Modulation of Energetics and Autophagy in Melanoma Cells. Cancer Treatment and Research Communications, 25:100210, doi: 10.1016/j.ctarc.2020.100210. PMID: 32987287 / PMCID: In Progress.
60. Parashar, D, A. Geethadevi, D. McAllister, J. Ebben, F. Peterson, D. Jensen, E. Bishop, S. Pradeep, B. Volkman, M.B. Dwinell, P. Chaluvally-Raghavan, and M.A. James. 2020. Targeted biologic inhibition of both tumor cell-intrinsic and intercellular CLPTM1L/CRR9-mediated chemotherapeutic drug resistance. Precision Oncology, In Revision.
61. SUBMITTED / IN REVISION: Vonderhaar, E.P., N.S. Barnekow, D. McAllister, L. McOlash, M. Abu Eid, M.J. Riese, V.L. Tarakanova, B.D. Johnson, and M.B. Dwinell. Systemic effects of intratumoral STING agonist therapy in non-immunogenic pancreatic ductal adenocarcinoma. In REVISION, Cell and Molecular Gastroenterology & Hepatology.
62. SUBMITTED / IN REVISION: Abu Eid, M, D. McAllister, L. McOlash, G. Cheng, K.A. Boyle, J. Zielonka, B.D. Johnson, B. Kalyanaraman, M.B. Dwinell. Inhibition of Oxidative Phosphorylation Remodels the Tumor Immune Microenvironment and Abrogates Melanoma Progression. IN REVISION,
63. SUBMITTED / IN REVISION: Hjortø, G., A. Jørgensen, E. Brandum, C. Goth, D. Boilesen, K. Egerod, N. Moussouras, F. Vilhardt, Y-H Chen, Z. Yang, M. Dwinell, B. Volkman, C. Veldkamp, P. Holst, M. Rosenkilde, and K. Orfin. Basic chemokine fragments are important regulators of immune activation - a case story from CCR7. eLIFE, submitted.
64. SUBMITTED / IN REVISION: Geethadevi, A., D. Parashar, Z. Ku, J. George, Y. Li, D. McAllister, I.P. Kadamberi, P. Gupta, M.B. Dwinell, H. Rui, N. Zhang, Z. An, S. Pradeep and P. Chaluvally-Raghavan. Target Oncostatin M Receptor-driven tumor growth and metastasis of ovarian cancer using monoclonal antibodies. Submitted.
 
Books, Chapters, and Reviews
1. Dwinell, M.B. and M.F. Kagnoff. 1999. Mucosal immunity. Current Opinion in Gastroenterology, 15: 33-38. PMID: 17023915
2. Dwinell, M.B., P.A. Johanesen, and J.M. Smith. 2003. Immunobiology of epithelial chemokines in the intestinal mucosa. Surgery, 133: 601-607. PMID: 12796725
3. Zimmerman, N.P., R.A. Vongsa, M.K. Wendt, and M.B. Dwinell. 2008. Chemokines and chemokine receptors in mucosal homeostasis at the intestinal epithelial barrier in inflammatory bowel disease. (Cover Art) Inflammatory Bowel Diseases. 14: 1000-1011. Epub 2008 May 1. PMID: 18452220 / PMCID: PMC4114077.
4. Roy, I., D.B. Evans, and M.B. Dwinell. 2014. Chemokines and chemokine receptors. Update on utility and challenges for the clinician. Surgery, 155: 961-973. Epub 2014 Feb 8, doi: 10.1016/j.surg.2014.02.006 PMID: 24856117 / PMCID: PMC4390364.
5. Roy, I., A. Getschman, B.F. Volkman, and M.B. Dwinell. 2017. CXCL12 agonist biased signaling in cancer. Molecular Carcinogenesis, 56(3):804-813. Epub 2016 Sep 20, doi: 10.1002/mc.22571. PMID: 27648825 / PMCID: PMC5479419.
6. Kalyanaraman, B., G. Cheng, M. Hardy, O. Ouari, A. Sikora, J. Zielonka, and M.B. Dwinell. 2017. Mitochondria-targeted metformins: Antitumour and redox signaling mechanisms. Interface Focus. Epub 2017 Feb 17 doi: 10.1098/rsfs.2016.0109. PMCID: PMC5311906.
7. Kalyanaraman, B., G. Cheng, M. Hardy, O. Ouari, A. Sikora, J. Zielonka, and M.B. Dwinell. 2017. Modified metformin as a more potent anticancer drug: Mitochondrial inhibition, redox signaling, antiproliferative effects and future EPR studies. Cell Biochemistry and Biophysics, 75(3-4):311-317. Epub: 2017 Apr 21 doi: 10.1007/s12013-017-0796-3 PMID: 28429253 / PMCID: PMC5680142.
8. Boyle, K.A., M.A. James, S. Tsai, D.B. Evans, and M.B. Dwinell. 2017. Stromal inflammation in pancreatic cancer: Mechanisms and translational applications. Pancreatic Cancer, 2nd Edition, edited by J.P. Neoptolemos, R.A. Urrutia, J.L. Abbruzzese, and M.W. Büchler, Springer Nature Publishing, New York, USA. doi:10.1007/978-1-4939-6631-8_55-1, Print ISBN: 978-1-4939-6631-8.
9. Kalyanaraman⁠, B.⁠, G. Cheng⁠, M. Hardy, O. Ouari⁠e, M. Lopez⁠, J. Joseph, J. Zielonka⁠, and M.B. Dwinell. 2017. ⁠A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds. Redox Biology, 14:316-327. Epub 2017 Sep 29. doi: 10.1016/j.redox.2017.09.020. PMID: 29017115 / PMCID: PMC5633086
10. IN PREP: Moussouras, N.A., B.F. Volkman, and M.B. Dwinell. Structure - function studies of CCL21-CCR7 in inflammation and cancer.
 
Editorials, Letters to Editor, Other
1. Binion, D.G., S. Kugathasan, and M.B. Dwinell. 2006. Molecular stratification of Crohn's disease by chemokine receptors: fractalkine receptor polymorphisms define a fibrostenosing ileal subgroup. Editorial, American Journal of Gastroenterology, 101: 107-109. PMID: 16405541
2. M.B. Dwinell. 2011. Science-Business eXchange, This Week in Therapeutics - Cancer. CXC chemokine receptor 4 (CXCR4; NPY3R); chemokine CXC motif ligand 12 (CXCL12; SDF-1). SciBX 4(43); doi:10.1038/scibx.2011.1202. Published online Nov. 3 2011
3. Roy, I, C.T. Veldkamp, B.F. Volkman, and M.B. Dwinell. 2013. Chemokines in colitis: microRNA control. Commentary, Gut, 63:1202-1204. doi:10.1136/gutjnl-2013-305886. PMID: PMID: 24142964 / PMCID: PMC4608425
4. Boyle, K.A. and M.B. Dwinell 2018. GEMMs are a gem when it comes to defining the role of HIF2alpha in mucinous cystic neoplasms. Editorial, Cellular and Molecular Gastroenterology and Hepatology, 5:165-166. doi: http://dx.doi.org/10.1016/j.jcmgh.2017.11.008. PMID: 29693045 / PMCID: PMC5904046
 
Non-Refereed Journal Publications/Original Papers
1. Dwinell, M.B. 1993. Intestinal myoelectric alterations in rats chronically infected with the tapeworm Hymenolepis diminuta. Madison, University of Wisconsin. Thesis, Master of Science.
2. Dwinell, M.B. 1996. Modulation of intestinal myoelectric activity in rats infected with the tapeworm Hymenolepis diminuta. Madison, University of Wisconsin. Dissertation, Doctor of Philosophy.
 
Abstracts
1. Dwinell, M.B., P. Bass and J.A. Oaks. 1994. Intestinal myoelectric alterations in rats chronically infected with the tapeworm Hymenolepis diminuta. FASEB J. 8(4): A568.
2. Dwinell, M.B. and J.A. Oaks. 1994. Intestinal myoelectric activity in rats treated with the anthelminthic Praziquantel. Proceedings Amer. Assoc. Veterinary Parasitologists 39th Annual Meeting, San Francisco, CA. (MBD Selected Oral Presentation)
3. Dwinell, M.B. and J.A. Oaks. 1994. Removal of tapeworm-associated myoelectric activity in rats infected with Hymenolepis diminuta and treated with the anthelmintic Praziquantel. Program and Abstracts, American Society of Parasitologists, 69th Annual Meeting. Fort Collins, CO. (MBD Selected Oral Presentation)
4. Dwinell, M.B. 1995. Is aerobic bacterial overgrowth a cause of intestinal myoelectric alterations in Hymenolepis diminuta infected rats? Annual Midwestern Conference of Parasitologists, 47th Annual Meeting, Milwaukee, WI. (Award: Best Student Oral Presentation)
5. Dwinell, M.B., P. Bass, and J.A. Oaks. 1996. Mucosal mast cell hyperplasia and smooth muscle hypertrophy during intestinal motility alterations in tapeworm infected rats. FASEB J. 10(3): A381.
6. Dwinell, M.B., P. Bass, D.M. Schaefer, and J.A. Oaks. 1996. Interactions between Hymenolepis diminuta and the rat host: intestinal transit and endogenous bacterial populations. Program and Abstracts, American Society of Parasitologists 71st Annual Meeting, Tucson, AZ. (MBD Selected Oral Presentation)
7. Oaks, J.A., M.B. Dwinell, R.M. Wise, and P. Bass. 1996. Adult Hymenolepis diminuta and the rat: an apparently benign relationship, but who is in charge? Annual Southwestern Association of Parasitologists, Lake Texoma, OK.
8. Dwinell, M.B., P. Bass, and J.A. Oaks. 1997. In vivo stimulation of Hymenolepis diminuta-specific intestinal myoelectric alterations in uninfected rats. Program and Abstracts, American Society of Parasitologists 72nd Annual Meeting, Nashville, TN. (MBD Selected Oral Presentation)
9. Dwinell, M.B., L. Eckmann, and M.F. Kagnoff. 1998. HT-29 human intestinal epithelial cells express mRNA and protein for tumor necrosis factor receptors I and II. Gastroenterology 114(4): A969.
10. Dwinell, M.B., L. Eckmann, and M.F. Kagnoff. 1999. Human intestinal epithelial cells express an array of CC and CXC chemokine receptors. Keystone Symposia on Molecular and Cellular Biology, Chemokines and Chemokine Receptors, Keystone, CO. (Jan. 18-23).
11. Dwinell, M.B., L. Eckmann, J.D. Leopard, and M.F. Kagnoff. 1999. Expression of chemokine receptors by human intestinal epithelial cells. Gastroenterology, 116(4): A703. (MBD Selected Oral Presentation)
12. Merendino, N., M.B. Dwinell, L. Eckmann, and M.F. Kagnoff. 1999. Expression of platelet activating factor receptors on human intestinal epithelial cells. Gastroenterology. 116(4): A774.
13. Dwinell, M.B., N. Lügering, L. Eckmann, and M.F. Kagnoff. 2000. Human intestinal epithelial cells secrete interferon-inducible T lymphocyte chemoattractants. Keystone Symposia on Molecular and Cellular Biology, Innate and Acquired Immunity at Mucosal Surfaces, Taos, NM. (MBD Selected Oral Presentation)
14. Merendino, N., M.B. Dwinell, L. Eckmann, and M.F. Kagnoff. 2000. Platelet activating factor receptor expression by intestinal epithelial cells in vitro and in vivo. Keystone Symposia on Molecular and Cellular Biology, Innate and Acquired Immunity at Mucosal Surfaces, Taos, NM.
15. Izadpanah, A., M.B. Dwinell, and M.F. Kagnoff. 2000. Regulated secretion of the T lymphocyte and dendritic cell chemokine macrophage inflammatory protein (MIP)-3 by human intestinal epithelial cells. Gastroenterology, 118(4): A94. (AI Selected Oral Presentation)
16. Eckmann, L., J.R. Smith, M.P. Housley, M.B. Dwinell, and M.F. Kagnoff. 2000. Analysis using high-density cDNA arrays of altered gene expression in human intestinal epithelial cells in response to infection with the invasive enteric bacteria Salmonella. Gastroenterology, 118(4): A100.
17. Dwinell, M.B., N. Lügering, L. Eckmann, and M.F. Kagnoff. 2000. Interferon (IFN)- regulated production of chemoattractants specific for CD4+ memory T cells by human intestinal epithelial cells. Gastroenterology, 118(4): A672. (MBD Selected Oral Presentation)
18. Berin, M.C., M.B. Dwinell, L. Eckmann, and M.F. Kagnoff. 2000. Regulated production of the Th2-lymphocyte chemoattractant macrophage derived chemokine (MDC) by human intestinal epithelial cells. Gastroenterology, 118(4): A793.
19. Ogawa, H., M.B. Dwinell, and M.F. Kagnoff. 2001. CCR6 is a functional signal transducing receptor on human intestinal epithelial cells. Gastroenterology, 120(5): A181.
20. Dwinell, M.B., H. Ogawa, and M.F. Kagnoff. 2001. The chemokine receptor CXCR4 is apically and basolaterally expressed on polarized colonic epithelial cells and is a functional receptor for its cognate ligand. Gastroenterology, 120(5): A319.
21. Heidemann, J., M.B. Dwinell, P. Rafiee, H. Ogawa, T.H. Lamirand, P.J. Fisher, M.F. Otterson, N. Lugering, W. Domschke, and D.G. Binion. 2002. Mechanisms of interleukin 8 (IL8) induced angiogenesis in human intestinal microvascular endothelial cells (HIMEC). Gastroenterology 122(4): A437.
22. Heidemann, J., H. Ogawa, P. Rafiee, C. Maaser, W. Domschke, D.G. Binion and M.B. Dwinell. 2003. Mucosal angiogenesis regulated by human intestinal microvascular endothelial cell expressed CXCR4 and its cognate ligand stromal cell-derived factor-1. FASEB J. 17(5): A802. (MBD Oral Presentation)
23. Johnson, N.A., M.B. Dwinell, D.G. Binion, S. Kugathasan. 2003. Expression of CXCR3, CXCR4, CCR5 in early and late pediatric Crohn's disease intestinal mucosal T-lymphocytes. Gastroenterology 124(4): A323.
24. Heidemann, J., H. Ogawa, P. Rafiee, C. Maaser, H. Gockel, W. Domschke, D.G. Binion and M.B. Dwinell. 2003. Human intestinal microvascular endothelial cells express CXCR4 and its cognate ligand stromal cell-derived factor-1. Gastroenterology 124(4): A596.
25. Dwinell M.B. and P.A. Johanesen. 2003. Mucosal host defense to Campylobacter jejuni. 10th Annual Midwest Microbial Pathogenesis Conference, Iowa City, IA. (MBD Oral Presentation)
26. Smith, J.M., P.A. Johanesen, and M.B. Dwinell. 2004. The chemokine SDF-1/CXCL12 stimulates intestinal epithelial cell migration and barrier integrity. Gastroenterology 126(4): A141. (Poster of Distinction, top 10% of submitted and peer-reviewed abstracts)
27. Johanesen, P.A. and M.B. Dwinell. 2004. Human intestinal epithelial cells secrete the dendritic cell chemoattractant MIP-3/CCL20 in response to infection by Campylobacter jejuni. Program and Abstracts, American Society of Microbiologists 104th General Meeting, New Orleans, LA.
28. Johanesen, P.A. and M.B. Dwinell. 2005. NF-B and intracellular calcium regulate intestinal epithelial expression of the dendritic cell chemokine macrophage inflammatory protein (MIP)3/CCL20 in response to infection with Campylobacter jejuni. FASEB J. 19(4): A380.
29. Wendt, M.K., P.A. Johanesen, and M.B. Dwinell. 2005. Constitutive intestinal epithelial expression of SDF1/CXCL12 is transcriptionally silenced by DNA hypermethylation in colorectal adenocarcinoma cells. FASEB J. 19(5): A1506. (MKW Oral Presentation)
30. Wendt, M.K., P.A. Johanesen, and M.B. Dwinell. 2005. Constitutive intestinal epithelial expression of stromal cell-derived factor-1/CXCL12 is transcriptionally silenced by DNA hypermethylation in colorectal adenocarcinoma cells. Gastroenterology 128(4): A140. (MKW Selected Oral Presentation)
31. Johanesen, P.A., and M.B. Dwinell. 2005. NF-B and intracellular calcium regulate intestinal epithelial expression of the dendritic cell chemokine macrophage inflammatory protein (MIP)3/CCL20 in response to infection with Campylobacter jejuni. Gastroenterology 128(4): A195.
32. Moyer, R.A., M.K. Wendt, P.A. Johanesen, and M.B. Dwinell. 2006. The chemokine CXCL12 regulates intestinal epithelial restitution by increasing actin rearrangement and activity of the Rho signaling pathway. Gastroenterology 130(4): A490. (Poster of Distinction, top 10% of submitted and peer-reviewed abstracts)
33. Wendt, M.K., P.A. Johanesen, N. Kang-Decker, V. Shah, and M.B. Dwinell. 2006. Epigenetic silencing of the chemokine CXCL12 in colorectal carcinoma regulates epithelial metastasis. Gastroenterology 130(4): A679.
34. Wendt, M.K., and M.B. Dwinell. 2007. Epigenetic silencing of CXCL12 in mammary carcinoma cells enhances metastasis. Keystone Symposia on Molecular Targets for Cancer, March 18th-23rd, Whistler, British Columbia, CANADA
35. Vongsa, R.A. and M.B. Dwinell. 2008. Parallel roles for human beta-defensin 2 (HBD2) and the inflammatory chemokine CCL20 in regulating restitution of model intestinal epithelium. Gastroenterology 134(4): A70. (RAV Selected Oral Presentation)
36. Wendt, M.K., L.J. Drury, R.A. Vongsa, and M.B. Dwinell. 2008. Basal ERK1/2 signaling induces anoikis in colorectal carcinoma cells following constitutive re-expression of the chemokine CXCL12. Gastroenterology 134(4): A304.
37. Drury, L.J. and M.B. Dwinell. 2009. Re-establishment of CXCL12 expression in colorectal carcinoma cells regulates anoikis through Bim-mediated intrinsic apoptosis. Proceedings of the American Association for Cancer Research 100th Annual Meeting 50: 791, A3271.
38. Zimmerman, N.P., R.A. Vongsa, P.A. Johanesen, M.K. Wendt, N.H. Salzman and M.B. Dwinell 2009. Targeted deletion of intestinal epithelial CXCR4 modulates epithelial barrier repair through altered ERK1/2 signaling. Digestive Disease Week Program 2009, pg 782.
39. Vongsa, R.A., K. A. Agle, and M.B. Dwinell. 2009. Calcium mobilization signaled by CXCL12 regulates integrin activation and cellular migration in intestinal epithelial cells. Digestive Disease Week Program 2009, pg 362. (RAV Selected Oral Presentation)
40. Drury, L.J. and M.B. Dwinell. 2009. CXCL12 chemokine expression induces anoikis of human colonic carcinoma cells through Bim upregulation. FASEB Summer Conferences: GI Tract XIII; Advances in the Molecular and Cell Biology of the Intestinal Epithelium: Development, Inflammation, Host Defense and Cancer, Snowmass, CO. (08/2009)
41. Hwang, S. and M.B. Dwinell. 2010. CXCL12 stimulation strengthens paracellular tightening and E-cadherin localization during intestinal epithelial restitution. Digestive Disease Week Program 2010, pg 363. (MBD Oral Presentation)
42. Drury, L.J., J.J. Ziarek, C.T. Veldkamp, N. Heveker, B.F. Volkman and M.B. Dwinell. 2010. Dimeric SDF-1/CXCL12 inhibits CXCR4-mediated metastasis of colorectal carcinoma. Gordon Research Conferences: Chemotactic Cytokines. Lucca (Barga) ITALY, May 30 - June 04, 2010.
43. Zimmerman, N.P. and M.B. Dwinell. 2010. cAMP regulates intestinal epithelial cell wound repair through PKA and the small GTPase RhoA. Gordon Research Conference on Cyclic Nucleotide Phosphodiesterases, Waterville Valley Resort, NH, June 13 - 18, 2010.
44. Agle, K.A., R.A. Vongsa, and M.B. Dwinell. 2011. CXCL12 stimulation leads to dynamic activation of laminin specific integrins promoting enterocyte adhesion and spreading. Experimental Biology 2011 Program, pg366. (KAA Oral Presentation)
45. Zimmerman, N.P., J.R. Turner, and M.B. Dwinell. 2011. cAMP abrogates intestinal epithelial restitution through PKA-dependent inhibition of actin remodeling. Digestive Disease Week Program 2011, pg. 796. (NPZ video presentation)
46. Drury, L.J., J.J. Ziarek, B.F. Volkman, and M.B. Dwinell. 2011. CXCL12 oligomerization dictates divergent signaling and migratory responses in human intestinal epithelial cells. Digestive Disease Week Program 2011, pg. 793. (Poster of Distinction, top 10% of submitted and peer-reviewed abstracts)
47. Zimmerman, N.P., I. Roy, J.M. Wilson, and M.B. Dwinell. 2012. Elevated cAMP decreases migratory potential in pancreatic cancer cells. Program of the American Association for Cancer Research Annual Meeting2012. Cancer Research 72(8 Suppl):473. doi:10.1158/1538-7445.AM2012-473.
48. Hwang, S., M.B. Dwinell. 2012. Chemokine signaling regulates E-cadherin localization through a ROCK and F-actin dependent mechanism during intestinal epithelial restitution. Digestive Disease Week Program 2012, pg 363. (SH Selected Oral Presentation)
49. Takekoshi, T., X. Wu, M.B. Dwinell, and S.T. Hwang. 2012. CXCR4 regulates lymphangiogenesis and keratinocyte proliferation in contact and IL23-mediated dermatitis. Society of Investigative Dermatology Annual Meeting, Raleigh, NC, May 9-May 12, 2012.
50. Roy, I., N.P. Zimmerman, S. Tsai, D.B. Evans, and M.B. Dwinell. 2012. CXCL12 and CXCR4 are reciprocally expressed in normal pancreatic ducts and pancreatic ductal adenocarcinoma respectively. Program of the American Association for Cancer Research, Pancreatic Cancer: Progress and Challenges, Lake Tahoe, NV, Cancer Research, 72(12 Suppl):A74. doi: 10.1158/1538-7445.PANCA2012-A74.
51. Walker, A.S., X. Chen, L. Gomez-Arellano, R. Ishan, M.B. Dwinell, S. Tsai, D. Evans, A.C. Mackinnon. 2013. TYMS and ERCC1 expression in naive and neoadjuvant-treated pancreatic cancer. American Pancreatic Association and International Association of Pancreatology 2012 Joint Meeting, Miami, FL. Pancreatology, 13(2): e83.
52. Wang, L., S. Cossette, M.B. Dwinell, D.A. Harder and R. Ramchandran, 2013. MMPs secreted by astrocytes are responsible for tumor cell invasion and metastasis. Gordon Research Conferences: Matrix Metalloproteinases Crucial Components of Molecular Networks and Disease Pathways, Lucca (Barga) ITALY, May 19-24, 2013.
53. Flister, M, A. Lemke, M.B. Dwinell, J. Shull, and H. Jacob. 2014. CXM - a new tool for genetic mapping of cancer risk in the tumor microenvironment. Program of the American Association for Cancer Research Annual Meeting 2014, April 5-9, 2014, San Diego, CA.
54. Roy, I., N.P. Zimmerman, A.C. Mackinnon, S. Tsai, D.B. Evans, and M.B. Dwinell. 2014. CXCL12 suppresses pancreatic cancer by regulating tumor cell growth, migration, and metastatic homing. Digestive Disease Week Program 2014, Chicago, IL, May 3-6, 2014.
55. Roy, I, D. McAllister, E. Gorse, K. Dixon, G. Cheng, A. Getschman, D. Engle, S. Tsai, D.A. Tuveson, D.B. Evans, B.F. Volkman, B. Kalyanaraman, and M.B. Dwinell. 2014. Chemokine biased agonists regulate pancreatic cancer migration and metastasis through bioenergetic signaling. Program of the American Association for Cancer Research, Pancreatic Cancer: Innovations in Research and Treatment, New Orleans, LA, Cancer Research, 75(13 Suppl):B55. doi: 10.1158/1538-7445.PANCA2014-B55.
56. Roy, I, D. McAllister, E. Gorse, K. Dixon, C.T. Piper, N.P. Zimmerman, A.E. Getschman, S. Tsai, D.D. Engle, D.B. Evans, B.F. Volkman, B. Kalyanaraman, and M.B. Dwinell. 2015. Chemokine biased agonism regulates pancreatic cancer migration and metastasis through bioenergetic signaling. Selected Abstracts, Midwest Tumor Microenvironment Meeting, University of Wisconsin, Madison, WI, May 11-13, 2015.
57. Flister, M., A. Lemke, M.B. Dwinell, C. Bergom, J. Shull, and H. Jacob. 2015. NextGen strategies for mapping genetic modifiers in the tumor microenvironment. Program of the American Association for Cancer Research Annual Meeting, April 5-9, 2015, Philadelphia, PA. Cancer Research 75(15 Suppl): A3217. doi:10.1158/1538-7445.AM2015-3217.
58. Roy, I., K. Boyle, A.C. Mackinnon, R. Hwang, S. Tsai, D.B. Evans, M.B. Dwinell. 2016. Chemokine directed migration of activated stellate cells in pancreatic ductal adenocarcinoma. Program of the American Association for Cancer Research Special Conference on Pancreatic Cancer: Advances in Science and Clinical Care, Orlando, FL. Cancer Research 76(24 Suppl):A21. doi: 10.1158/1538-7445.PANCA16-A21.
59. Boyle, K., I. Roy, R. Hwang, S. Tsai, D.B. Evans and M.B. Dwinell. 2016. CCL28-CCR10 mediate chemotactic migration of activated tumor associated fibroblasts in pancreatic cancer. Selected Abstracts, 2nd Annual Midwest Tumor Microenvironment Meeting, University of Minnesota, Minneapolis, MN, May 18-20, 2016.
60. Roy, I., B.F. Volkman, and M.B. Dwinell. 2016. Chemokine biased agonism regulates tumor cell migration and metastasis through bioenergetic signaling. Gordon Research Conference: Chemotactic Cytokines, May 29-June 3, 2016, Girona, SPAIN.
61. Vonderhaar, E.P., I. Roy, D. McAllister, and M.B. Dwinell. 2017. Favorable effects of CXCL12 biased signaling on pancreatic cancer progression. Selected Abstracts, Midwest Tumor Microenvironment Meeting, Washington University, St. Louis, MO, April 24-26, 2017.
62. Vonderhaar, E.P., I. Roy, D.M. McAllister, M.A. James, and M.B. Dwinell. 2017. Effects of biased CXCL12 signaling on pancreatic adenocarcinoma growth. Selected Abstracts, Midwest Pancreatic Cancer Symposium, Chicago, IL, October 12-13, 2017.
63. Boyle, K.A. J. Van Wickle, J. Zielonka, B. Kalyanaraman, and M.B. Dwinell. 2018. Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation. Program of the American Association for Cancer Research Annual Meeting, April 14-18, 2018, Chicago, IL. Cancer Research 78(13 Suppl): A878. doi: 10.1158/1538-7445.AM2018-878
64. Vonderhaar, E.P., I. Roy, D. McAllister, and M.B. Dwinell. 2018. High concentrations of CXCL12 decrease pancreatic adenocarcinoma growth. Journal of Clinical and Translational Science, A2543. doi: 10.1017/cts.2018.79.
65. Moussouras, NA, C.T. Veldkamp, B.F. Volkman, and M.B. Dwinell. 2018. Structural studies into autoinhibition by CCL21. Chemotactic Cytokines Gordon Conference: The Chemokine System at the Crossroads of Physiology and Disease, Jordan Hotel at Sunday River, Maine, USA. (NAM Selected for Oral Presentation)
66. Boyle, K.A., J. Van Wickle, B. Kalyanaraman, and M.B. Dwinell. 2018. Activation of mitophagy-mediated anti-proliferative program upon treatment of colon cancer cells with mitochondrial-targeted compounds. Selected Abstracts, Midwest Tumor Microenvironment Meeting, University of Iowa, Iowa City, IA, May 2018.
67. McAllister, D, W. Jing, B.D. Johnson, and M.B. Dwinell. 2018. Immune modulation of the pancreatic cancer tumor microenvironment via STING agonist. Selected Abstracts, Midwest Tumor Microenvironment Meeting, University of Iowa, Iowa City, IA, May 2018.
68. Dwinell, M.B., B.D. Johnson, W. Jing, D. McAllister, and E. Vonderhaar. 2019. Innate immune activation of anti-tumor T cell responses in pancreatic cancer. Selected Abstracts, Midwest Tumor Microenvironment Meeting, University of Notre Dame, South Bend, IN, May 2019.
69. Roy, I., B. Binder-Markey, D. Sychowski, D. McAllister, D. D’Andrea, C. Franz, M. Dwinell, and R. Lieber. A novel approach to the development of pre-clinical models of cancer rehabilitation. Submitted for presentation at the Association of Academic Physiatrists Annual Meeting, New Orleans, LA, Feb 1-5, 2021.
70. Roy, I., B. Binder-Markey, D. Sychowski, D. McAllister, D. D’Andrea, C. Franz, M.B. Dwinell, R. Lieber. Rehabilitating cachexia - development and functional characterization of a novel longitudinal and translational model of cancer-associated cachexia. Society on Sarcopenia, Cachexia and Wasting Disorders Annual Meeting. Journal of Cachexia, Sarcopenia and Muscle.