CURRICULUM VITAE
Phaedra Tachtatzis MD
Phaedra Tachtatzis MD
Associate Professor
Department of Medicine
Division of Gastroenterology
Department of Medicine
Division of Gastroenterology
OFFICE ADDRESS: |
Froedtert Hospital |
9200 W Wisconsin Ave |
Milwaukee, WI 53226 |
EDUCATION: |
09/1991 - 07/1992 Ten GCSEs, Sydenham High School for Girls, London, United Kingdom, London |
09/1992 - 07/1994 Five A-levels, Rainham Mark Grammar School, Kent, United Kingdom, Kent |
09/1994 - 07/1999 MB ChB, University of Aberdeen, Aberdeen, SC, United Kingdom, Scotland |
08/2000 - 07/2002 MRCP, Membership of the Royal College of Physicians, London, United Kingdom, England |
10/2007 - 2015 MD, University of Aberdeen, Aberdeen, United Kingdom, Cambridge |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
08/1999 - 08/2000 Pre-Registration House Officer, Aberdeen Royal Infirmary, Aberdeen, United Kingdom |
08/2000 - 08/2002 Senior House Officer, Oxford Deanery Medical Rotation, Oxford, United Kingdom |
08/2002 - 01/2003 Senior House Officer, Intensive Care Medicine, Royal Victoria Infirmary, New Castle, United Kingdom |
01/2003 - 11/2003 Locum Appointment for Training, Gastroenterology & GIM, Royal Berkshire & Battle Hospitals, Reading, United Kingdom |
11/2003 - 09/2004 Specialist Registrar (NTN), Gastroenterology & GIM, Darlington Memorial Hospital, United Kingdom |
09/2004 - 10/2005 Specialist Registrar (NTN), Freeman Hospital, New Castle, United Kingdom |
10/2005 - 10/2006 Specialist Registrar (NTN), Gastroenterology & GIM, South Tyneside District Hospital, South Shields, United Kingdom |
10/2006 - 10/2007 Specialist Registrar (NTN), Hepatology Fellow, Hepatology, Freeman Hospital, New Castle, United Kingdom |
10/2007 - 04/2010 Specialist Registrar (NTN), Out of Programme Research: Hepatology Research Registrar, Hepatology, Addenbrooke’s Hospital, Cambridge, England |
04/2010 - 12/2011 Specialist Registrar (NTN), Gastroenterology & GIM, University Hospital of North Durham, New Castle, United Kingdom |
01/2012 - 09/2012 Hepatology Fellow, Hepatology, King’s College Hospital, London, England |
FACULTY APPOINTMENTS: |
09/2012 - 08/2023 Consultant Hepatologist, Leeds Teaching Hospitals NHS Trust, St James’s University Hospital, United Kingdom, Leeds |
08/2023 - Present Associate Professor of Medicine, Medicine, Gastroenterology and Hepatology, Medical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226 |
HOSPITAL STAFF PRIVILEGES: |
09/2012 - 08/2023 Leeds Teaching Hospitals NHS Trust, St James’s University Hospital, United Kingdom, Leeds |
08/2023 - Present Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Avenue, Milwaukee, WI 53226 |
SPECIALTY BOARDS AND CERTIFICATION: |
Licensure | Number | Issue Date | Expiration |
General Medicine Council | 4602066 | 2009 | None |
AWARDS AND HONORS: |
07/1994 University Entrance Bursary |
07/1994 George Thomson Bursary |
07/1995 Distinction in Genetics |
07/1995 Distinction in Cell Biology |
07/1995 Distinction in Physiology |
07/1995 Distinction in Statistics |
07/1995 Distinction in Biochemistry |
07/1995 Distinction in Chemistry |
07/1996 First Class Honours in Biochemistry |
07/1996 Bursaries awarded for academic excellence |
07/1996 First Class Honours in Physiology |
07/1997 Distinction in Medical Microbiology |
07/1997 Bursaries awarded for academic excellence |
07/1998 Bursaries awarded for academic excellence |
07/1999 Dr C E Anderson memorial fund award for elective project Distinction in Medicine
|
08/2000 Letter of commendation for overall performance as a first year SHO |
03/2005 Travel award for AASLD awarded by BASL |
03/2011 Young Investigator’s Bursary awarded by EASL |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
01/2001 - 01/2012 European Association for the Study of the Liver |
07/2002 - Present Royal College of Physicians of London |
01/2004 - Present British Society of Gastroenterology |
01/2005 - Present British Association for the Study of the Liver |
INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
International |
Chronic Hepatitis B Infection and Telomeres, Digestive Disease Week, Chicago, United States, 03/2009 |
Alcoholic Liver Disease: EASL Monothematic Conference, Athens, Greece, 12/2010 |
Astellas Development Programme in Transplantation, Barcelona, Spain, 05/2012 |
Janssen-Sponsored Hepatitis C Workshop, Madrid, Spain, 04/2014 |
Waiting List Patient Monitoring and Optimization, Continuing Education Program, Leeds, England, 07/2021 |
Can Liver Biopsy Guide the Management of Deranged Liver Function Tests in Liver Transplant Recipients Receiving Kaftrio?, European Cystic Fibrosis Conference, Rotterdam, The Netherlands, 06/2022 |
National |
Liver Course, King’s College Liver Course, London, England, 11/2002 |
Colonoscopy Course, James Cook University Hospital, Middlesbrough, England, 07/2004 |
Clinical Nutrition Day, New Castle, United Kingdom, 09/2004 |
Advances in Hepatitis C Management, London, England, 03/2005 |
Capsule Endoscopy Course, Durham. England, 05/2006 |
Cambridge Liver Symposium, Cambridge, England, 10/2008 |
Cambridge Liver Symposium, Cambridge, England, 10/2009 |
Management & Leadership Skills, London, England, 02/2010 |
Advanced Life Support, Papworth Hospital, Cambridge, England, 03/2010 |
CV and Interview Skills, New Castle, United Kingdom, 05/2010 |
Advanced Liver Transplantation Workshop, London, England, 01/2011 |
Masterclass in Chronic Hepatitis B&C, King’s College Hospital, London, England, 04/2011 |
HIV-HBV Co-Infection, North of England HBV meeting, Leeds, England, 11/2012 |
Masterclass in immunosuppression, Delivered Lecture on Post-Transplant HCV Recurrence, Leeds, England, 05/2013 |
Masterclass in Viral Hepatitis, Presented a Challenging Case, London, England, 05/2013 |
Speaker and Conference Organizer, Leeds Hepatology Course, Leeds, England, 11/2013 |
Presentation of Leeds Liver Unit experience of triple antiviral therapy for HCV and Q&A session as expert panel member, Hepatitis C in the UK: a real-world perspective, London, England, 11/2013 |
Speaker and contributor to national guidelines, BTS LDLT guidelines, London, England, 11/2013 |
Invited case presentation, UK & Eire Liver Transplant Meeting, Cambridge, England, 01/2014 |
Training the Trainers Course, Leeds, England, 05/2014 |
Talk on Resistance in Chronic Hepatitis B Infection, Birmingham, England, 05/2014 |
National Workshop on Graft Utilisation, BTS NHSBT Congress, 02/2021 |
Regional |
Speaker and Conference Co-Organizer, Yorkshire & the Humber Liver Network Liver Transplant Symposium, Leeds, England, 12/2013 |
North of England Viral Hepatitis, Sheffield, England, 01/2014 |
Training the Trainers Course, Leeds, England, 05/2014 |
Regional Hepatitis C Symposium, Sheffield, England, 06/2014 |
Frailty and Wait List Management, Leeds Referrer’s Day, Leeds, England, 10/2019 |
Regional RCP Study Day, Leeds, England, 05/2020 |
Frailty and Wait List Management, Leeds Referrer’s Day, Leeds, England, 10/2021 |
Local |
Metabolic Liver Disease, Annual AASLD Meeting Review, Milwaukee, WI, 02/10/2024 |
Chair: Debates and Dilemmas in the Management of Pre-Transplant Patients, Transplant Symposium, 04/13/2024 |
Strategies to Reduce Frailty & Optimize Nutrition in Liver Disease, Transplant Symposium, 04/05/2025 |
Strategies to Reduce Frailty & Optimize Nutrition in Liver Disease, Transplant Service Line Educational Lectures, 04/11/2025 |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Newton JL, Hudson M, Tachtatzis PM, Sutcliffe K, Pairman J, Burt JA & Jones DE. Population prevalence and symptom associations of autonomic dysfunction in primary biliary cirrhosis. Hepatology. 2007 Jun;45(6):1496-505. PMID: 17538969 |
2. Tachtatzis PM, Brais R & Alexander G. An instance of hepatic steatosis in HBV infection. Viral Hepatitis in Practice. 2009;1(2)4-5. |
3. Alfahad A, Thet EM, Radwan F, Sudhakar J, Nini K & Tachtatzis PM. Spontaneous Incomplete transverse subtrochanteric femoral fracture with cortical thickening possibly secondary to risedronate use: a case report. Journal of medical case reports. 2012;6(1):272. PMID: 22943389 |
4. Verma S, Tachtatzis PM, Penrhyn-Lowe S, Scarpini C, Jurk D, Von Zglinicki T, Coleman N & Alexander GJ. Sustained telomere length in hepatocytes and cholangiocytes with increasing age in normal liver. Hepatology. 2012 Oct;56(4):1510-20. PMID: 22504828
|
5. Davis M & Tachtatzis PM. From haemochromatosis to liver transplant. BMJ. 2013;347:f4423. PMID: 23963547 |
6. Aravinthan A, Scarpini C, Tachtatzis PM, Verma S, Penrhyn-Lowe S, Harvey R, Davies SE, Allison M, Coleman N & Alexander GJ. Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease. Journal of Hepatology. 2013 Mar;58(3):549-56. PMID: 23142622 |
7. Tachtatzis PM, Marshall A, Aravinthan A, Verma S, Penrhyn-Lowe S, Mela M, Scarpini C, Davies SE, Cole-man N, Alexander GJ. Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis. PLoS One. 2015. May 29;10(5): e0127511. PMID: 26024529 |
8. Tachtatzis PM, Marshall A, Aravinthan A, Verma S, Penrhyn-Lowe S, Mela M, Scarpini C, Davies SE, Coleman N, Alexander GJM. Correction: Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis. PLoS One. 2015 Jul 28;10(7):e0134315. doi: 10.1371/journal.pone.0134315. eCollection 2015. PMID: 26218071 |
9. Hill QA, Harrison LC, Padmakumar AD, Owen RG, Prasad KR, Lucas GF, Tachtatzis P. A fatal case of transplantation-mediated alloimmune thrombocytopenia following liver transplantation. Hematology. 2017. Apr;22(3):162-167. PMID: 27764999 |
10. Fararjeh FA, Mahmood S, Tachtatzis P, Yallop D, Devereux S, Patten P, Agarwal K, Suddle A, O'Grady J, Heaton N, Marcus R, Kassam S. A retrospective analysis of post-transplant lymphoproliferative disorder following liver transplantation. Eur J Haematol. 2018. Jan;100(1):98-103. PMID: 29094407 |
11. Vionnet J, Miquel R, Abraldes JG, Wall J, Kodela E, Lozano J, Ruiz P, Navasa M, Marshall A, Nevens F, Gel-son, W, Leithead J, Masson S, Jaeckel E, Taubert R, Tachtatzis P, Eurich D, Simpson KJ, Bonaccorsi-Riani E, Femg S, Bucuvalas J, Ferguson J, Quaglia A, Sidorova J, Elstad M, Douiri A, Sanchez-Fueyo A. Non-invasive alloimmune risk stratification of long-term liver transplant recipients. J Hepatol. 2021;75:1409-1419. PMID: 34437910 |
12. Tachtatzis P, Spoletini G, Clifton I, Etherington C, Peckham D. Changes in liver biochemistry and tacrolimus levels following the introduction of elexacaftor/tezacaftor/ivacaftor in patients with cystic fibrosis and liver transplant. J Cyst Fibros. 2023 May 8:S1569-1993(23)00129-7. doi: 10.1016/j.jcf.2023.04.023. Online ahead of print. PMID: 37164896. |
13. Vionnet J, Torres-Yaguana J, Miquel R, Abraldes JG, Wall J, Kodela E, Lozano JJ, Ruiz P, Navasa M, Marshall A, Nevens F, Gelson W, Leithead J, Masson S, Jaeckel E, Taubert R, Tachtatzis P, Eurich D, Simpson KJ, Bonaccorsi-Riani E, Ferguson J, Quaglia A, Demetris AJ, Lesniak AJ, Elstad M, Delord M, Douiri A, Rebollo-Mesa I, Martinez-Llordella M, Silva JAF, Markmann JF, Sánchez-Fueyo A. Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression. Am J Transplant. 2025 May;25(5):1045-1058. doi: 10.1016/j.ajt.2024.12.002. Epub 2024 Dec 18. PMID: 39706366. |
Abstracts |
1. Vionnet J, Miquel R, Abraldes JG, Lozano JJ, Ruiz P, Navasa M, Marshall A, Nevens F, Gelson W, Leithead J, Masson S, Jaeckel E, Taubert R, Tachtatzis P, Eurich D, Simpson K, Bonaccorsi-Riani E, Ferguson J, Quaglia A, Elstad M, Delord M, Douiri A, Sánchez-Fueyo A. The clinical utility and safety of biomarker-guided immunosuppression withdrawal in liver transplantation: the LIFT prospective RCT. Southampton (UK): National Institute for Health and Care Research; 2025 Apr. PMID: 40238953. |