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CURRICULUM VITAE

Robert Niebler MD
Associate Professor
Department of Pediatrics
Division of Critical Care

OFFICE ADDRESS:
Children's Hospital
9000 W Wisconsin Ave
Milwaukee, WI 53226

EDUCATION:
08/1994 - 05/1997 B.S., Marquette University, Milwaukee, WI
08/1997 - 05/2001 M.D., Medical College of Wisconsin, Milwaukee, WI

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
07/2001 - 06/2004 Resident, Pediatrics, University of Arizona, Tucson, AZ
07/2004 - 06/2005 Chief Resident, Pediatrics, University of Arizona, Tucson, AZ
07/2005 - 06/2008 Fellow, Pediatric Critical Care, Medical College of Wisconsin, Milwaukee, WI
07/2008 - 06/2009 Fellow, Pediatric Cardiac Critical Care, Medical College of Wisconsin, Milwaukee, WI

FACULTY APPOINTMENTS:
07/2005 - 06/2009 Instructor, Department of Pediatrics, Division of Critical Care, The Medical College of Wisconsin, Milwaukee, WI
07/2009 - 06/2016 Assistant Professor, Department of Pediatrics, Division of Critical Care, The Medical College of Wisconsin, Milwaukee, WI
07/2016 - Present Associate Professor, Department of Pediatrics, Division of Critical Care, Medical College of Wisconsin, Milwaukee, WI

HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:
08/2013 - Present Epic Provider Builder, Children's Hospital of Wisconsin, Milwaukee, WI
04/01/2019 - 03/31/2021 Critical Care Section Chief, Children's Hospital of Wisconsin, Milwaukee, WI
07/01/2020 - Present Assistant Medical Director, Cardiac Critical Care Unit, Children's Wisconsin, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:
07/2004 - 06/2005 Northwest Medical Center, 6200 La Cholla Blvd., Tucson, AZ 85741
07/2005 - Present Children's Hospital of Wisconsin, 9000 W. Wisconsin Avenue, Wauwatosa, WI 53226
04/2014 - 06/2016 St. Joseph's/Marshfield Clinic-Security Health Plan, 1515 N Saint Joseph Avenue, PO Box 8000, Marshfield, WI 54449-8000
07/31/2018 - 07/14/2020 Pediatrics, Hospital Medicine, Wheaton Franciscan Healthcare-All Saints, 3801 Spring Street, Racine, WI 53405

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
American Board of Pediatrics-General Pediatrics
12/2004
12/2024
American Board of Pediatrics-Pediatric Critical Care
01/2009
12/2020
 
Certificates
Issued By Issue DateExpiration
Physician Builder
Epic
11/13/2013
None
Physician Builder-Reporting
Epic
07/22/2014
None
Physician Builder-Orders
Epic
09/19/2014
None
PALS
AAP/AHA
03/28/2018
03/2020
ACLS
ACS
10/2020
10/2022
Advanced Cardiovascular Life Support
None
 

Licensure
Number Issue DateExpiration
Arizona License
32678
04/07/2004
09/01/2005
Wisconsin License
47905-20
03/15/2005
10/2021
 

AWARDS AND HONORS:
04/2008 Honorable Mention Clinical Research Award, Medical College of Wisconsin-Department of Pediatrics Joint Fellowship Curriculum Pediatric Fellows Research Day
05/2011 William Williams, MD Young Investigator Award, 7th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion Conference
01/2013 Top Rated Doctors, M Magazine
2013 - 2014 Outstanding Medical Student Teacher, Medical College of Wisconsin, Bench to Bedside Course
2014 - 2015 Outstanding Medical Student Teacher, Medical College of Wisconsin, Molecules to Cells Course
2017 - 2018 Outstanding Medical Student Teacher, Medical College of Wisconsin, Critical Care Pediatrics Course
2017 - 2018 Outstanding Medical Student Teacher, Medical College of Wisconsin, Bench to Bedside Course
11/2018 Top Doctors, Milwaukee Magazine
2018 - 2019 Outstanding Medical Student Teacher, Medical College of Wisconsin, Bench to Bedside Course
2019 - 2020 Outstanding Medical Student Teacher, Medical College of Wisconsin, Bench to Bedside Course
04/2020 Top Doctors, Milwaukee Magazine

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
07/2001 - 06/2013 American Academy of Pediatrics
07/2005 - 06/2013 Society of Critical Care Medicine
02/2008 - Present Pediatric Cardiac Intensive Care Society

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Editorial Board
07/01/2020 - Present Artificial Organs
Journal Review
12/2011 - Present Artificial Organs
01/2012 - Present Pediatric Cardiology
01/2013 - Present Journal of Pediatrics
11/2013 - Present Annals of Thoracic Surgery
01/2014 - Present Pediatric Critical Care Medicine
11/2014 - Present Clinical Medicine Insights: Cardiology
07/2016 - Present Journal of Pediatric Surgery
04/2018 - Present Cardiology in the Young

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
08/2013 - 12/2014 Member, Database Committee, PC4: Pediatric Cardiac Critical Care Consortium
08/2018 - Present Member, Leadership Committee, ACTION Learning Network
08/2018 - Present Co-Chair, Utilization and Value Committee, ACTION Learning Network

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Non-Peer Review
Title:
A Randomized, Open-Label, Active Controlled, Safety and Extrapolated Efficacy Study of Apixaban in Pediatric Subjects Requiring Anticoagulation for the Treatment of a Venous Thromboembolic Event
Source:
Pfizer
Role:
Site Co-Investigator
PI:
Rowena Punzalan
Dates:
04/2015 - Present
 
Title:
A Prospective, Open-Label, Active-Controlled Study to Evaluate the Pharmacokinetics, Pharamcodynamics, Safety, and Efficacy of Rivaroxaban for Thromboprophylaxis in Pediatric Subjects 2 to 8 years of Age after the Fontan Procedure
Source:
Janssen
Role:
Site-Principal Investigator
Dates:
11/2016 - Present
 
Title:
A Phase 3, Open-Label, Randomized, Multi-Center, Controlled Trial to Evaluate the Pharmacokinetics and Pharmacodynamics of Edoxaban and to Compare the Efficacy and Safety of Edoxaban with Standard of Care Anticoagulant Therapy in Pediatric Subjects from Birth to less than 18 years of age with Confirmed Venous Thromboembolism
Source:
Daiichi Sankyo, Inc.
Role:
Site-Principal Investigator
Dates:
09/2017 - Present
 
Prior
Peer Review
Title:
Pilot Innovative Research Award-Antithrombin III Supplementation Prior to Cardiopulmonary Bypass in Neonates with Single Ventricle Heart Disease and Aortic Arch Hypoplasia
Source:
Children's Research Institute
Role:
Principal Investigator
Dates:
07/2010 - 12/2012
Direct Funds:
$26,000
 
Title:
Perioperative hemostasis in infants undergoing cardiopulmonary bypass
Source:
Children's Hospital of Wisconsin/Medical College of Wisconsin
Role:
Co-Investigator
PI:
Dudley Benson, MD
Dates:
07/01/2013 - 06/30/2016
Direct Funds:
$3,000,000
 
Title:
Total Cell-Free Deoxyribonucleic Acid (total cf-DNA) as a predictor of severity of illness and outcome following pediatric cardiac surgery
Source:
Clinical and Translational Science Institute of Southeast Wisconsin
Role:
Co-Investigator
PI:
Michael Mitchell and Jake Scott
Dates:
04/01/2018 - 03/31/2020
Direct Funds:
$50,000
 
Title:
Nitric oxide administration during pediatric cardiopulmonary bypass surgery to prevent platelet activation
Source:
Clinical and Translational Science Institute of Southeast Wisconsin
Role:
Principal Investigator
Dates:
04/01/2018 - 03/31/2019
Direct Funds:
$50,000
 
Non-Peer Review
Title:
Berlin Heart EXCOR Pediatric Ventricular Assist Device IDE Trial
Source:
Berlin Heart Inc.
Role:
Site Co-Investigator
PI:
James S. Tweddell, MD
Dates:
11/23/2007 - 11/30/2010
 
Title:
A Phase 1, Open-Label, Single-Dose, Non-Randomized Study to Evaluate Pharmacokinetics and Pharmacodynamics of Edoxaban in Pediatric Patients
Source:
Daiichi-Sankyo
Role:
Site-Principal Investigator
Dates:
02/2015 - 02/2020
 
Title:
SynCardia 50cc Temporary Total Artificial Heart (TAH-t) for Bridge To Transplant (BTT)
Source:
Syncardia Systems, Inc.
Role:
Site Co-Investigator
PI:
Ronald Woods, MD/PhD
Dates:
09/2015 - 02/2020
 
Title:
Pediatric Cardiac-Hemostasis and Thrombosis
Source:
Children's Research Institute
Role:
Principal Investigator
Dates:
07/01/2016 - 06/30/2017
Direct Funds:
$17,272
 
Title:
Single-Dose Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Apixaban in Pediatric Subjects at Risk for a Venous or Arterial Thrombotic Disorder
Source:
Bristol-Myers Squibb
Role:
Site-Principal Investigator
Dates:
07/2016 - 09/2019
 

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Niebler RA, ECMO in the Emergency Department, Pediatric Emergency Medicine Grand Rounds, Medical College of Wisconsin, 03/2010
Niebler RA, Inotropes in Abdominal Surgery and Trauma, Pediatric Surgery Educational Conference, Medical College of Wisconsin, 08/2011
Niebler RA, Anticoagulation in the Pediatric CICU, Pediatric CICU Lecture Series, Medical College of Wisconsin, 11/2012
Niebler RA, NIRS: The Next "Vital" Sign, Pediatric Surgery Education Conference, Medical College of Wisconsin, 12/14/2012
Niebler RA, VAD and Mechanical Circulatory Support in Pediatrics, Pediatric Cardiolgy Core Lecture Series, Medical College of Wisconsin, 09/04/2013
Niebler RA, Peri-Operative Anticoagulation Medication Management, Multidisciplinary Pediatric Surgery Conference, Medical College of Wisconsin, 03/07/2014
Niebler RA, Mechanical Circulatory Support in Single Ventricle Anatomy, S. Bert Litwin Lectureship, Herma Heart Center, Children's Hospital of Wisconsin, 10/01/2015
Niebler RA, Ventricular Assist Device Support in Singel Ventricle Patients, Gallen Lectureship, Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee, WI, 06/16/2016
Niebler RA, Keep 'Er Movin: Coagulation System and Testing in the ICU, Neurointensive Care Educational Lecture, Medical College of Wisconsin, Froedtert Hospital, Milwaukee, WI, 05/28/2019
 
Regional
Niebler RA, Clinical Research and the FDA-Compassion, Emergencies and your own IND, Wisconsin Chapter of the Association of Clinical Research Professionals, Milwaukee, WI, 09/12/2018
 
National
Niebler RA, Antithrombin in ECMO: Beneficial or Not, 31st Annual CNHS Symposium: ECMO and the Advanced Therapies for Respiratory Failure, Keystone, CO, 02/23/2015
 
International
Niebler RA, Medical Management of Neuropsychological Issues Associated with Mechanical Circulatory Support, Fourth Annual Cardiac Neurodevelopmental Symposium, Milwaukee, WI, 06/05/2015
Niebler RA, ECMO in the Pediatric Hem/Onc/HSCT Patient, American Society of Pediatric Hematology/Oncology 30th Annual Meeting, Montreal, Quebec, Canada, 04/29/2017
Niebler, RA, Moderator-Pediatric 2: Overcoming the Limits of Design: Miniturization, Portability and Affordability in Children, ASAIO 64th Annual Conference, Washington D.C., USA, 06/2018
Niebler RA, Panelist-Right Ventricular Failure: A Case-Focused Panel Discussion, International Pediatric VAD and Heart Failure Summit, Stanford, CA, USA, 09/2018
Niebler RA, Zinn M, Right Heart Failure and Biventricular Support Options, ACTION Learning Network Learning Session, Virtual, 08/13/2020
 

PEER REVIEWED WORKSHOPS/PRESENTATIONS:
National
Niebler RA, Hyperosmolar Hyperglycemic Coma in a Nineteen-Year-Old Down Syndrome Patient, Poster Presentation: American Academy of Pediatrics National Convention, San Francisco, CA, 10/2004
Berg MD, Samson RA, Donnerstein RL, Clark LL, Indik JH, Niebler RA, Berg DD, Kern KB, Berg RA, P-Waves During Ventricular Fibrillation (VF) May Result in Malfunction of the Automated External Defibrillator (AED), Poster Presentation: American Heart Association Resuscitation Science Symposium, Dallas, TX, 11/2005
Gamez M, Niebler RA, Lankiewicz MW, Punzalan RC, Risk of Thrombosis with Recombinant Factor VIIa During Extra Corporeal Membrane Oxygenation, Oral Presentation: American Association of Blood Banks Annual Meeting, Miami Beach, FL, 10/2006
Gaies M, Jeffries H, Niebler R, Thiagarajan R, Scheurer M, Vasoactive Inotropic Score (VIS) is Associtated with Outcome After Infant Cardiac Surgery: A Report of the Pediatric Cardiac Critical Care Consortium (PC4), Oral Presentation: American College of Cardiology Annual Meeting, San Francisco, CA, 03/2013
Niebler RA, Egodage SN, Ghanayem NS, Berger S, Shah TK, Woods RK, Mitchell ME, Tweddell JS, Zangwill SD, Mechanical Circulatory Support and Outcomes of Pediatric Heart Transplantation, Oral Presentation: Southern Thoracic Surgery Association 60th Annual Meeting, Scottsdale, AZ, 11/2013
Scott JP, Niebler RA, Stuth EA, Benson DW, Woods RK, Tweddell JS, Cole R, Mitchell ME, Bercovitz RS, Simpson P, Montgomery R, Mast A, Maroney S, Yan K, Punzalan R, Newman DK, Proactive Platelet and Cryoprecipitate Transfusion during Neonatal Cardiopulmonary Bypass Rapidly Normalizes Platelet Count, Fibrinogen, and Functional Rotational Thromboelastometry Parameters, Oral Presentation: 96th Annual Meeting of the American Association of Thoracic Surgery, Baltimore, MD, 05/2016
Hoffman GM, Scott JP, Stuth EA, Niebler RA, Mitchell ME, Tweddell JS, Ghanayem NS, Mussatto KA, Effect of Antifibrinolytic Drug on Hemodynamics in Neonates Undergoing the Norwood Procedure, Oral Presentation: Annual Meeting of the American Society of Anesthesiologists, Chicago, IL, 10/2016
Niebler RA, Kindel SJ, Hraska V, Woods RK, Conversion of Failed Single Ventricle Palliation to in Series Circulation and Total Artificial Heart, Podium Presentation: American Society of Artificial Internal Organs 64th Annual Conference, Washington DC, USA, 06/15/2018
Niebler RA, Brickler M, Hawkins J, Schmidt J, Weber E, Kindel SJ, Woods RK, Compassion, Field Trips, and the Long Journey Home: A Case Study in Pediatric Mechanical Circulatory Support, Virtual Poster Presentation-American Society of Artificial Internal Organs Annual Meeting, Virtual, 05/2020
Scott JP, Tanem J, Michell A, Laulederkind A, Niebler R, Bertrandt R, Hraska V, Woods RW, Mitchell ME, Association of preoperative cell-free DNA levels and outcome following pediatric cardiopulmonary bypass, American Heart Association Scientific Sessions, Virtual, 11/13/2020 - 11/17/2020
 
International
Niebler RA, Christensen M, Lankiewicz M, McArthur J, Fresh Frozen Plasma Transfusion is not Associated with a Change in the Oxygenation Index in the Pediatric Intensive Care Unit, Poster Presentation: Pediatric Critical Care Colloquium, Whistler, BC Canada, 02/2008
Niebler RA, Ghanayem N, Brabant C, Thromboelastography compared to Standard Coagulation Testing in Evaluation of Coagulopathies after Cardiopulmonary Bypass, Poster Presentation: Pediatric Cardiac Intensive Care Society International Conference, Miami Beach, FL, 12/2008
Niebler RA, Christensen M, Wellner H, Berens R, Antithrombin Replacement during Extracorporeal Membrane Oxygenation, Oral Presentation: Seventh International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion, Philadelphia, PA, 05/2011
Niebler RA, Lew S, Zangwill SD, Woods RK, Mitchell ME, Tweddell JS, Ghanayem NS, Incidence and Outcome of Pediatric Patients with Intracranial Hemorrhage while supported on Ventricular Assist Devices, Oral Presentation: Ninth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion, Hershey, PA, 05/2013
Niebler RA, Scott JP, Cole R, Stuth E, Shah T, Benson D, Tweddell J, Whole Blood Versus Reconstituted Whole Blood for Cardiopulmonary Bypass Surgery in Infants, Poster Presentation: 60th Annual Scientific and Standardization Committee of the International Society of Thrombosis and Haemostasis, Milwaukee, WI, 06/2014
Parker H, Simpson P, Dasgupta M, Niebler RA, Impact of Anticoagulation Strategy on ECMO Bleeding and Thrombotic Complications, Oral Presentation: Eleventh International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion, Verona, Italy, 06/2015
Niebler RA, Woods K, Ghanayem NS, Hoffman G, Mitchell M, Punzalan R, Scott JP, Simpson P, Tweddell JS, A Pilot Study of Antithrombin Replacement Prior to Cardiopulmonary Bypass in Neonates, Oral Presentation: Eleventh International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion, Verona, Italy, 06/2015
Brenner MK, Bercovitz RS, Cole R, Niebler RA, Scott J, Stuth E, Mitchell M, Tweddell J, Woods R, Benson DW, Newman DK, Assessment of Platelet Function and Hemostasis in Neonates Undergoing Cardiopulmonary Bypass, Poster Presentation: XXV Congress of the International Society on Thrombosis and Haemostasis, Toronto, Canada, 06/2015
Auerbach SR, Richmond ME, Schumacker KR, Lopez-Colon D, Mitchell MB, Turrentine MW, Cantor RS, Niebler RA, Eghtesady P, Infectious Complications fo Ventricular Assist Device Use in Children in the US: Data from the Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs), Oral Presentation: 36th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation, Washington DC, USA, 04/2016
Conway J, Miera O, Henderson HT, VanderPluym C, Buchholz H, Fenton M, Niebler RA, Padalino M, Slaughter M, Lorts A, Schweiger M, Hassan M, Schmitto JD, Scheel JN, Martin B, Li Y, Parrino PE, Morales DL, Kirk R, Global Experience with the Heartware HVAD in Pediatric Patients: A Preliminary Analysis, Oral Presentation: 36th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation, Wahington D.C. USA, 04/2016
Imielske B, Niebler RA, Kindel S, Woods R, HeartWare Ventricular Assist Device Implantation for Failing Fontan Physiology, Oral Presenation: 12th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion, New York City, NY, USA, 05/2016
Jeewa A, Imamura M, Canter C, Niebler RA, VanderPluym C, Rosental D, Kirklin JK, McMullan M, Morell V, Turrentine M, Ameduri R, Nguyen K, Kanter K, Conway J, Gajarski R, Fraser C, Post-Transplant Outcomes of Patients Supported wiht the Berlin Heart EXCOR as a Bridge to Transplantation: A Multi-Institutional Sudy, Oral Presentation-37th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation, San Diego, CA, USA, 04/2017
Niebler RA, Scott JP, Stuth E, Cole R, Newman D, Bercovitz R, Simpson P, Dasgupta M, Woods RK, Rotational Thromboelastometry Values Do Not Correlate with Severe Bleeding in Neonatal Surgery Utilizing Cardiopulmonary Bypass, Oral Presentation: 13th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion, Rome, Italy, 09/2017
Hoffman G, Ghanayem N, Mitchell ME, Woods RK, Tweddell JT, Musatto K, Stucke A, Stuth E, Scott JP, Niebler RA, Bertrandt R, Hraska V, Identification of Time-Dependent Risks of Hemodynamic States following Stage 1 Norwood Palliation, Oral Presentation: Society of Thoracic Surgeons 55th Annual Meeting, San Diego, CA, USA, 01/29/2019
C. VanderPluym, M. O'Connor, A. Lorts, M. Ploutz, D. Peng, S. Law, M. Zinn, R. Niebler, D. Rosenthal, J. Conway, S. Auerbach, D. Sutcliffe, M. Mehegan, Anti-Coagulation Management in Pediatric Ventricular Assist Device: A Quality Improvement Target, Oral Presentation: 39th Annual Meeting and Scientific Sessions: International Society of Heart and Lung Transplant, Orlando, FL, USA, 04/03/2019
Amidon MD, Yan K, Zhang J, Niebler RA, 4-Factor Prothrombin Complex Concentrate Use in Pediatric Patients with Ventricular Assist Device Presenting for Cardiac Transplant, Oral Presentation: 15th International Conference on Pediatric Mechanical Circulatory Support and Pediatric Cardiopulmonary Perfusion, New York City, NY, USA, 05/07/2019
Niebler RA, Amdani S, Blume B, Cantor R, Deng L, Kirklin JK, Lorts A, Morales DL, Rosenthal DN, Ghanayem NG, Stroke in pediatric ventricular assist device patients-a PediMACS registry analysis, Oral Presentation-International Society of Heart and Lung Transplant Annual Meeting, Virtual, 04/2020
Tanem J, Scott JP, Niebler RA, Otto M, Bertrandt R, Stamm K, Mitchell ME, Total cell-free DNA (TCF) predicts death and adverse events following pediatric cardiothoracic surgery, Congenital Heart Surgeons Society and European Congenital Heart Surgeons Association Joint Annual Meeting, Virtual, 10/24/2020 - 10/25/2020
 

COMMITTEE SERVICE:
Medical College of Wisconsin
01/2013 - 12/2014 Member, Practice Excellence Committee, Children's Specialty Group
06/2013 - Present Co-Chair, Epic Provider Champion, Children's Specialty Group
 
Hospital
07/2005 - 06/2009 Member, Code Committee, Children's Hospital of Wisconsin
06/2011 - 06/2017 CICU Physician Representative, CLA-BSI Collaborative, Critical Care, Children's Hospital of Wisconsin
11/2011 - 06/2013 Critical Care Representative, iStrategy Provider Core Group, Children's Hospital of Wisconsin
07/2013 - Present Member, Documentation Standards Committee, Children's Hospital of Wisconsin
07/2013 - Present Member, Electronic Health Record Provider Committee, Children's Hospital of Wisconsin
10/2013 - Present Co-Chair, Clinical Decision Support, Children's Hospital of Wisconsin
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Student Education
09/2006 - 12/2009 Case Based Discussion Group Moderator, M1, Medical Biochemistry Course; 4 hours/yr
12/2007 - Present Course Instructor, M4 Pediatric Problem Solving; 50 hours/yr
12/2008 - 12/2010 Facilitator, Pediatric Component to the Clinical Examination and Reasoning Course; 4 hours/yr
03/2010 - 03/2012 Small Group Preceptor, M2 Clinical Examination and Reasoning Course; 20 hours/yr
05/2012 - Present Molecules to Cells Course Clinical Based Discussion Clinician Moderator and Case Author, 20 hours/year
01/2014 - Present M1/M2 Bench to Bedside Course Instructor, 20 hours/yr
07/2015 - Present M3 Pediatric Clerkship History and Physical Reviewer, 10 hours/year
 
Resident and Fellow Education
09/2007 - 09/2012 A Fellow's Guide to ECMO, Annual Lecture to Critical Care Section, 4 hours/yr
09/2008 - 09/2012 Ace the Boards-Pediatric Review Course, Critical Care Review, Children's Hospital of Wisconsin, 4 hours/yr
 

EXTRAMURAL TEACHING:
Community/Lay Public
08/2011 - 01/2012 Children's Hospital of Wisconsin-ECMO Specialists, Anticoagulation Management during Extracorporeal Membrane Oxygenation, 10 hours/year
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
Parker H, Medical College of Wisconsin, 12/2014 - 06/2015 M4 Research Elective Mentor, Abstract presented as oral presentation at international conference, published manuscript
 
Clinical/Research Fellows
Amidon MD, Medical College of Wisconsin, 09/2017 - 06/2020, Abstract presented as oral presentation at international conference, recipient of young investigator award, manuscript submitted for publication
 
Residents
Imielski B, Medical College of Wisconsin, 01/2016 - 07/2016 Research Mentor, Abstract presented as oral presentation at international conference, recipient of young investigator award, published manuscript
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Heidenreich JW, Higdon TA, Kern KB, Sanders AB, Berg RA, Niebler R, Hendrickson J, Ewy GA. Single-rescuer cardiopulmonary resuscitation: 'two quick breaths'--an oxymoron. Resuscitation. 2004 Sep;62(3):283-9.
2. Niebler RA, Punzalan RC, Marchan M, Lankiewicz MW. Activated recombinant factor VII for refractory bleeding during extracorporeal membrane oxygenation. Pediatr Crit Care Med. 2010 Jan;11(1):98-102.
3. Niebler RA, Christensen M, Berens R, Wellner H, Mikhailov T, Tweddell JS. Antithrombin replacement during extracorporeal membrane oxygenation. Artif Organs. 2011 Nov;35(11):1024-8.
4. Gandy KL, Mitchell ME, Pelech AN, Niebler RA, Hoffman G, Berger S. Aortic exclusion: a method of handling aortic insufficiency in the pediatric population needing mechanical circulatory support. Pediatr Cardiol. 2011 Dec;32(8):1231-3.
5. Niebler RA, Christensen M, and McArthur J. Plasma transfusion and lung injury in the pediatric intensive care unit. Journal of Blood Disorders and Transfusion. 2012; 3(2): 1-3.
6. Niebler RA, Gill JC, Brabant CP, Mitchell ME, Nugent M, Simpson P, Tweddell JS, Ghanayem NS. Thromboelastography in the assessment of bleeding following surgery for congenital heart disease. World J Pediatr Congenit Heart Surg. 2012 Oct 01;3(4):433-8.
7. Almond CS, Morales DL, Blackstone EH, Turrentine MW, Imamura M, Massicotte MP, Jordan LC, Devaney EJ, Ravishankar C, Kanter KR, Holman W, Kroslowitz R, Tjossem C, Thuita L, Cohen GA, Buchholz H, St Louis JD, Nguyen K, Niebler RA, Walters HL 3rd, Reemtsen B, Wearden PD, Reinhartz O, Guleserian KJ, Mitchell MB, Bleiweis MS, Canter CE, Humpl T. Berlin Heart EXCOR pediatric ventricular assist device for bridge to heart transplantation in US children. Circulation. 2013 Apr 23;127(16):1702-11.
8. Niebler RA, Lew SM, Zangwill SD, Woods RK, Mitchell ME, Tweddell JS, Ghanayem NS. Incidence and outcome of pediatric patients with intracranial hemorrhage while supported on ventricular assist devices. Artif Organs. 2014 Jan;38(1):73-8.
9. Niebler RA, Mitchell ME, Scott JP. Repeated aortopulmonary shunt thrombosis in a neonatal patient with a low antithrombin level. World J Pediatr Congenit Heart Surg. 2014 Jan 01;5(1):94-6.
10. Niebler RA, Ghanayem NS, Shah TK, De La Rosa Bobke A, Zangwill S, Brosig C, Frommelt MA, Mitchell ME, Tweddell JS, Woods RK. Use of a HeartWare ventricular assist device in a patient with failed Fontan circulation. Ann Thorac Surg. 2014 Apr;97(4):e115-6.
11. Gaies MG, Jeffries HE, Niebler RA, Pasquali SK, Donohue JE, Yu S, Gall C, Rice TB, Thiagarajan RR. Vasoactive-inotropic score is associated with outcome after infant cardiac surgery: an analysis from the Pediatric Cardiac Critical Care Consortium and Virtual PICU System Registries. Pediatr Crit Care Med. 2014 Jul;15(6):529-37. PMCID: PMC4159673
12. Niebler RA, Shah TK, Mitchell ME, Woods RK, Zangwill SD, Tweddell JS, Berger S, Ghanayem NS. Ventricular Assist Device in Single-Ventricle Heart Disease and a Superior Cavopulmonary Anastomosis. Artif Organs. 2016 Feb;40(2):180-4.
13. Niebler RA, Woods KJ, Murkowski K, Ghanayem NS, Hoffman G, Mitchell ME, Punzalan RC, Scott JP, Simpson P, Tweddell JS. A Pilot Study of Antithrombin Replacement Prior to Cardiopulmonary Bypass in Neonates. Artif Organs. 2016 Jan;40(1):80-5.
14. Imielski BR, Niebler RA, Kindel SJ, Woods RK. HeartWare Ventricular Assist Device Implantation in Patients With Fontan Physiology. Artif Organs. 2017 Jan;41(1):40-46.
15. Auerbach SR, Richmond ME, Schumacher KR, Lopez-Colon D, Mitchell MB, Turrentine MW, Cantor RS, Niebler RA, Eghtesady P. Infectious complications of ventricular assist device use in children in the United States: Data from the Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs). J Heart Lung Transplant. 2018 01;37(1):46-53. PMCID: PMC5849428
16. Woods RK, Niebler RA, Kindel S, Mitchell ME, Tweddell JS, Hraska V. Multiple Mechanical Support Modalities and Cardiac Transplantation in a Young Child with Corrected Transposition. J Thorac Cardiovasc Surg. 2017 Dec 13 (Epub ahead of print).
17. Bercovitz RS, Shewmake AC, Newman DK, Niebler RA, Scott JP, Stuth E, Simpson PM, Yan K, Woods RK. Validation of a definition of excessive postoperative bleeding in infants undergoing cardiac surgery with cardiopulmonary bypass. J Thorac Cardiovasc Surg. 2018 05;155(5):2112-2124.e2.
18. Woods RK, Kindel SJ, Mitchell ME, Hraska V, Niebler RA. Total Artificial Heart Using Bilateral Paracorporeal Pulsatile Ventricular Assist Devices in an 8.2-kg Child. Ann Thorac Surg. 2018 06;105(6):e255-e257.
19. Conway J, Miera O, Adachi I, Maeda K, Eghtesady P, Henderson HT, Guleserian K, Fan CS, Kirk R, Pediatric VAD Investigators. Worldwide Experience of a Durable Centrifugal Flow Pump in Pediatric Patients. Semin Thorac Cardiovasc Surg. 2018 Autumn;30(3):327-335.
20. Niebler RA, Parker H, Hoffman GM. Impact of Anticoagulation and Circuit Technology on Complications During Extracorporeal Membrane Oxygenation. ASAIO J. 2019 Mar/Apr;65(3):270-276.
21. Scott JP, Niebler RA, Stuth EAE, Newman DK, Tweddell JS, Bercovitz RS, Benson DW, Cole R, Simpson PM, Yan K, Woods RK. Rotational Thromboelastometry Rapidly Predicts Thrombocytopenia and Hypofibrinogenemia During Neonatal Cardiopulmonary Bypass. World J Pediatr Congenit Heart Surg. 2018 07;9(4):424-433.
22. Woods RK, Niebler R, Kindel S, Troshynski T, Joyce LD, Hraska V. A new method for implanting a total artifical heart in the patient with a Fontan circulation. J Thorac Cardiovasc Surg. 2019 01;157(1):353-355.
23. Jeewa A, Imamura M, Canter C, Niebler RA, VanderPluym C, Rosenthal DN, Kirklin JK, Cantor RS, Tresler M, McMullan DM, Morell VO, Turrentine M, Ameduri R, Nguyen K, Kanter K, Conway J, Gajarski R, Fraser CD , Jr.,. Long-term outcomes after transplantation after support with a pulsatile pediatric ventricular assist device. J Heart Lung Transplant. 2019 04;38(4):449-455.
24. VanderPluym CJ, Adachi I, Niebler R, Griffiths E, Fynn-Thompson F, Chen S, O'Connor MJ, Machado D, Hawkins B, Bleiweis MS, Koehl DA, Cantor RS, Morales D, Lorts A. Outcomes of children supported with an intracorporeal continuous-flow left ventricular assist system. J Heart Lung Transplant. 2019 04;38(4):385-393.
25. Maroney SA, Peterson JA, Zwifelhofer W, Martinez ND, Yan K, Niebler RA, Stuth EAE, Scott JP, Bercovitz RS, Woods RK, Mast AE. Erratum to: "Erratum to: Plasma proteolytic cascade activation during neonatal cardiopulmonary bypass surgery". Thromb Haemost. 2019 01;119(1):187.
26. Hoffman GM, Scott JP, Ghanayem NS, Stuth EA, Mitchell ME, Woods RK, Hraska V, Niebler RA, Bertrandt RA, Mussatto KA, Tweddell JS. Identification of Time-Dependent Risks of Hemodynamic States After Stage 1 Norwood Palliation. Ann Thorac Surg. 2020 01;109(1):155-162.
27. Niebler RA. Acquired von Willebrand Syndrome in Pediatric Extracorporeal Membrane Oxygenation: Sheared and Cleaved Everywhere, but What to Do About It? Pediatr Crit Care Med. 2019 10;20(10):998-999.
28. Woods RK, Kindel S, Mitchell ME, Hraska V, Niebler RA. Evolving understanding of total artificial heart support of young infants and children. J Thorac Cardiovasc Surg. 2020 03;159(3):1075-1082.
29. Zwifelhofer NMJ, Bercovitz RS, Cole R, Yan K, Simpson PM, Moroi A, Newman PJ, Niebler RA, Scott JP, Stuth EAD, Woods RK, Benson DW, Newman DK. Platelet Function Changes during Neonatal Cardiopulmonary Bypass Surgery: Mechanistic Basis and Lack of Correlation with Excessive Bleeding. Thromb Haemost. 2020 Jan;120(1):94-106. PMCID: PMC7003188
30. VanderPluym CJ, Cantor RS, Machado D, Boyle G, May L, Griffiths E, Niebler RA, Lorts A, Rossano J, Sutcliffe DL, Lytrivi ID, Buchholz H, Fynn-Thompson F, Hawkins B, Conway J. Utilization and Outcomes of Children Treated with Direct Thrombin Inhibitors on Paracorporeal Ventricular Assist Device Support. ASAIO J. 2019 Nov 20.
31. Lorts A, Smyth L, Gajarski RJ, VanderPluym CJ, Mehegan M, Villa CR, Murray JM, Niebler RA, Almond CS, Thrush P, O'Connor MJ, Conway J, Sutcliffe DL, Lantz JE, Zafar F, Morales DLS, Peng DM, Rosenthal DN. The Creation of a Pediatric Health Care Learning Network: The ACTION Quality Improvement Collaborative. ASAIO J. 2020 04;66(4):441-446.
32. Niebler RA, Amdani SM, Blume B, Cantor RS, Deng L, Kirklin JK, Lorts A, Morales D, Rosenthal DN, Ghanayem NS. Stroke in Pediatric Ventricular Assist Device Patients-A PediMACS Registry Analysis. J Heart Lung Transplant. 2020 Apr;39(4S):S129-S130.
33. Hoffman GM, Niebler RA, Scott JP, Bertrandt RA, Wakeham MK, Thompson NE, Ghanayem NS, Stuth EA, Mitchell ME, Woods RK, Hraska V, Mussatto KA, Tweddell JS. Interventions Associated With Treatment of Low Cardiac Output After Stage 1 Norwood Palliation. Ann Thorac Surg. 2020 Jul 08.
34. Niebler RA, Chiang-Ching H, Daley K, Janecke R, Jobe SM, Mitchell ME, Varner K, Woods K, Scott JP. Nitric Oxide Added to the Sweep Gas of the Oxygenator during Cardiopulmonary Bypass in Infants: A Pilot Randomized Controlled Trial. Artificial Organs; In Press.
35. Niebler RA, Chiang-Ching H, Daley K, Janecke R, Jobe SM, Mitchell ME, Varner C, Woods K, Scott JP. Nitric oxide added to the sweep gas of the oxygenator during cardiopulmonary bypass in infants: A pilot randomized controlled trial. Artif Organs. 2020 Aug 01.
36. VanderPluym CJ, Cantor RS, Machado D, Boyle G, May L, Griffiths E, Niebler RA, Lorts A, Rossano J, Sutcliffe DL, Lytrivi ID, Buchholz H, Fynn-Thompson F, Hawkins B, Conway J. Utilization and Outcomes of Children Treated with Direct Thrombin Inhibitors on Paracorporeal Ventricular Assist Device Support. ASAIO J. 2020 08;66(8):939-945.
 
Books, Chapters, and Reviews
1. Meyer M, Niebler R, Quasney M. "Extracorporeal Membrane Oxygenation" in Current Concepts in Pediatric Critical Care. Society of Critical Care Medicine; Mount Prospect, IL 2011
2. Hehir DA, Niebler RA, Brabant CC, Tweddell JS, Ghanayem NS. Intensive care of the pediatric ventricular assist device patient. World J Pediatr Congenit Heart Surg. 2012 Jan 01;3(1):58-66.
3. Giglia TM, Dinardo J, Ghanayem NS, Ichord R, Niebler RA, Odegard KC, Massicotte MP, Yates AR, Laussen PC, Tweddell JS. Bleeding and thrombotic emergencies in pediatric cardiac intensive care: unchecked balances. World J Pediatr Congenit Heart Surg. 2012 Oct 01;3(4):470-91.
4. Woods RK, Ghanayem NS, Mitchell ME, Kindel S, Niebler RA. Mechanical Circulatory Support of the Fontan Patient. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2017 Jan;20:20-27.
5. Niebler RA, Lehmann LE. "ECMO use in the Pediatric Immunocompromised Hematology/Oncology Patient" in Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient-An Evidence Based Guide. Springer International Publishing; Cham, Switzerland 2019.
 
Peer Reviewed Educational Products
1. Niebler RA. Critical Appraisal of: Cambonie G, Milesi C, Fournier-Favre S, et al. Clinical Effects of Heliox Administration for Acute Bronchiolitis in Young Infants. Chest 2006; 129:676-682. In The PedsCCM Evidence-Based Journal Club, October 2, 2006. Available from: http://pedsccm.org/view.php?id=308. Accessed May 8, 2008.
2. Niebler RA. Critical Appraisal of: Khan H, Belsher J, Yilmaz M, Afessa B, Moore SB, Hubmayr RD, Gajic O. Fresh frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients. Chest 2007 131:1308-1314 . In The PedsCCM Evidence-Based Journal Club, April 5, 2008. Available from: http://pedsccm.org/view.php?id=476. Accessed May 8, 2008.
 

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