Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

CURRICULUM VITAE

Stanley F. Lo PhD
Professor
Department of Pathology
Division of Administration

OFFICE ADDRESS:
Children’s Wisconsin - Milwaukee Hospital
8915 W Connell Court
Milwaukee, WI 53226

EDUCATION:
09/1981 - 05/1985 BA, Chemistry, St. Olaf College, Northfield
09/1985 - 08/1992 PhD, Bioorganic Chemistry, University of Minnesota, Minneapolis

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
08/1992 - 06/1993 Postdoctoral Fellow, Bioorganic Chemistry, University of Minnesota, Minneapolis, MN
07/1993 - 03/1997 Postdoctoral Research, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.
07/1993 - 03/1997 Fellow, Clinical Chemistry, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO
07/1995 - 06/1996 Chief Fellow, Clinical Chemistry, Washington University School of Medicine, St. Louis, MO

FACULTY APPOINTMENTS:
09/1991 - 05/1992 Adjunct Lecturer, Department of Chemistry, University of St. Thomas, St. Paul, MN
04/1997 - 06/2005 Assistant Professor, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI.
07/2005 - 06/2019 Associate Professor, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI
07/2019 - Present Professor, Department of Pathology, Medical College of Wisconsin

EDUCATIONAL ADMINISTRATIVE APPOINTMENTS:
03/2012 - 09/2013 Course-Director (interim), Resident Chemistry Rotation, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI
09/2018 - Present Course-Director, Resident Chemistry Rotation, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI
07/2019 - Present Co-Director, Clinical Chemistry Fellowship Program, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI (program MCWAH approved, acquiring COMACC accreditation, currently on hold)

HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:
04/1997 - Present Technical Director, Clinical Chemistry and Point of Care Testing, Children's Hospital of Wisconsin, Milwaukee, W53226
01/2001 - Present Director, Reference Standards Laboratory, Children's Hospital of Wisconsin, Milwaukee, WI 53226
01/2006 - Present Co-Director, Biochemical Genetics Laboratory, Children's Hospital of Wisconsin, Milwaukee, WI 53226
06/2006 - 09/2006 Administrative Director (interim), Laboratory Services, Children's Hospital of Wisconsin, Milwaukee, WI 53226
10/2006 - Present Associate Director, Clinical Pathology, Children's Hospital of Wisconsin, Milwaukee, WI 53226

HOSPITAL STAFF PRIVILEGES:
05/1997 - Present Children's Hospital of Wisconsin, 9000 W. Wisconsin Ave., Milwaukee, WI 53226

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
American Board of Clinical Chemistry (AACC) Sept
1998
None
   
AWARDS AND HONORS:
2006 - Present Albert A. Dietz Service Award, Chicago Section, AACC
2008 - Present AACC Outstanding Speaker Award, >4.5/5.0 for all speaker evaluations
2009 - Present AACC Outstanding Speaker Award, >4.5/5.0 for all speaker evaluations
2010 - Present AACC Outstanding Speaker Award, >4.5/5.0 for all speaker evaluations
2011 - Present Samuel Natelson Senior Investigator Award, Chicago Section, AACC
2012 - Present AACC SYCL Mentor of the Month (May), Society for Young Clinical Laboratorians, AACC
2013 - Present Outstanding Faculty Service Award, Medical College of Wisconsin
2014 - Present Professor Alvin Dubin Award for service to the Academy and the profession, National Academy of Clinical Biochemistry (now AACC Academy)
2014 - Present Outstanding Contributions to Pediatric and Maternal-Fetal Clinical Chemistry, AACC
2015 - Present Outstanding Faculty Service Award, Medical College of Wisconsin
2016 - Present Outstanding Faculty Service Award, Medical College of Wisconsin

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
1985 - Present American Chemical Society
1993 - Present AACC
1994 - 2016 American Association for Advancement of Science
2000 - Present Academy of Clinical Laboratory Physicians and Scientists
2000 - Present AACC Academy (formerly National Academy of Clinical Biochemistry
2001 - Present North American Chinese Clinical Chemistry Association
2001 - Present Society for Inherited Metabolic Disorders

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Editorial Board
2016 - Present Journal of Applied Laboratory Medicine
Journal Review
1997 - Present Clinical Chemistry
2001 - Present The Journal of Pediatrics
2003 - Present Clinical Chimica Acta
2004 - Present Archives in Pathology and Laboratory Medicine
2005 - Present Clinical Chemistry and Laboratory Medicine
2008 - Present Clinical Biochemistry
2009 - Present Annals of Clinical Biochemistry
2010 - 2011 European Journal of Pediatrics
2015 - Present JAMA Pediatrics
2015 - Present Journal of Applied Laboratory Medicine
Ad-Hoc Reviewer
1998 - 2001 2004-2008, 2010-19 Judge, Student Posters, AACC Annual Meeting
1999 - 2010 Reviewer, ACCENT® Review Board, review CE program applications, AACC
2004 - 2015 Reviewer, Distinguished Abstracts, AACC Academy

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
1996 - Present Member, Legislative Committee, Midwest Section, AACC
1999 - Present Chair, Corporate Liaison, Chicago Section, AACC
2001 - Present Chair and Educational Program Director, Wisconsin Satellite, Chicago Section, AACC
2002 - 2011 Member, Nominating Committee, Chicago Section, AACC
2005 - Present & 2015 Chair ('05), Awards Committee, Chicago Section, AACC
2005 - Present & 2015 Chair, Nominating Committee, Chicago Section, AACC

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
1995 - 1998 Corresponding Committee Consultant, Continuing Education Committee, AACC
2001 - 2006 Director (elected), 2002-05 Secretary/Treasurer (elected), American Board of Clinical Chemistry
2002 - 2004 Workshop Coordinator, 2004 Annual Meeting Organizing Committee, AACC
2003 - 2004 AACC Liaison, College of American Pathologists (CAP) Chemistry Resource Committee
2004 - 2007 Chair, Translation Committee for Thyroid NACB LMPG, NACCCA
2004 - 2005 President-Elect, North American Chinese Clinical Chemistry Association (NACCCA)
2004 - 2005 Member, Membership Committee, National Academy of Clinical Biochemistry (NACB)
2004 - 2011 Member, Subcommittee on the Expression of Uncertainty of Measurement (C51-P), Clinical Laboratory Standards Institute (CLSI, formerly NCCLS)
2004 - 2005 Member, AACC Nominating Committee (elected)
2005 - 2006 President, NACCCA
2005 - 2006 Newsletter Editor, Publications Committee, NACB
2005 - 2011 Member, Chemistry Resource Committee, CAP
2005 - 2008 Member, Meetings Management Group, AACC
2006 - 2012 Member, Pediatric Reference Range Committee, AACC
2006 - 2007 Past-President, NACCCA
2006 - 2007 Member, Nominating/Awards Committee for Pediatric Maternal/Fetal Division (elected)
2007 - 2012 Member, Pediatric and Maternal Fetal Division, Editorial Board, AACC
2007 - 2009 Member, Board of Directors, NACB
2007 - 2009 Symposia Coordinator, 2009 Annual Meeting Organizing Committee, AACC
2008 - 2010 Member, Subcommittee on Sweat Testing (C34-A3), CLSI
2008 - 2009 Member, Nominating/Awards Committee for Pediatric Maternal/Fetal Division (appointed)
2009 - 2011 Observer, Subcommittee Newborn Screening for Cystic Fibrosis I/LA35, CLSI
2010 - Present Chair Breakout Group 4 - Process for Assessing Successful Harmonization for an Analyte. AACC conference: Improving Clinical Laboratory Testing through Harmonization: An International Forum October 26, NIST, Gaithersburg, MD
2010 - 2014 Advisor, Executive Committee, NACCCA
2010 - 2012 Co-Chair, 2012 47th Annual Laboratory Medicine Meeting, Milwaukee, WI May 31 - June 2, 2012, Academy of Clinical Laboratory Physicians and Scientists
2010 - 2011 Member, Subcommittee on Metrologic Traceability and its Implementation (EP32-R), CLSI
2011 - Present Member, Van Slyke Foundation Advisory Group, AACC
2011 - Present Member, Program Coordinating Committee, AACC
2011 - Present President-Elect, NACB
2012 - Present President, NACB
2012 - 2013 Member, International Consortium for Harmonization of Clinical Laboratory Working Group, CAP
2012 - 2017 Consultant (ad hoc) to Chemistry Resource Committee
2013 - Present Past-President, NACB
2015 - 2016 Member, Subcommittee on Sweat Testing - Revision of C34-A3, CLSI
2015 - Present Member, Program Coordinating Committee, AACC
2015 - 2016 Member, Endocrinology Division, Executive Committee, Communication Officer, Newsletter Editor, and Listserv Co-moderator (2015), AACC.
2015 - 2017 Chair, AACC 2017 Annual Meeting Organizing Committee
2015 - 2016 Member, Annual Meeting Strategic Advisory Group, AACC
2016 - 2017 Member, TDM/Tox Division, Nominating Committee, AACC (elected)
2016 - 2018 Member, AACC Education Core Committee
2018 - 2019 Member, Chemistry Resource Committee, CAP
2018 - 2020 Member, Sweat Test Advisory Committee, Cystic Fibrosis Foundation
2018 - 2020 Member, Nominating Committee, AACC (elected)
2019 - 2022 Member, Clinical Chemistry Committee, CAP
2019 - 2022 Chair, AACC Awards Committee (appointed)

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Prior
Peer Review
Title:
Validity of Neuron Specific Enolase and S100B Serum Levels in Predicting Neurocognitive and Behavioral Outcomes in Children with Moderate to Severe Closed Traumatic Brain Injury: A Pilot Study
Source:
Injury Research Center, Medical College of Wisconsin
Role:
Co-investigator
Dates:
01/01/2003 - 12/31/2006
  
Title:
A Multi-Center Study of a New Method of Sweat Testing: the CF Quantum® Sweat Test
Source:
PolyChrome Medical, Inc (Legacy of Angels)
Role:
Sub-investigator
Dates:
2014 - 2015
  
Title:
Evaluation of Lactate for the Identification of Severely Injured Children
Source:
Children's Research Institute Pilot Innovation Research
Role:
Co-investigator
Dates:
01/2015 - 12/2015
Direct Funds:
$49,737
  
Non-Peer Review
Title:
Neonatal Network Study - Serum Total Bilirubin Standardization
Source:
Henk Vreman, PhD, Stanford University School of Medicine, Department of Pediatrics, Division of Neonatal & Developmental Medicine
Role:
Co-investigator and Network Participant
Dates:
01/01/3 - 12/31/6
  
Title:
Fresh Frozen Serum Project. College of American Pathologists, Chemistry Resource Committee
Source:
College of American Pathologists, Northfield, IL
Role:
Co-investigator
Dates:
01/01/3 - 2007
  
Title:
Tissue Transglutaminase and Endomysial Antibodies as Screening Tests for Celiac Disease.
Source:
Children's Hospital of Wisconsin
Role:
Co-investigator
Dates:
11/11/3 - 11/11/4
  
Title:
Bilirubin CVL Pilot Project
Source:
College of American Pathologists, Northfield, IL
Role:
Consultant
Dates:
07/15/4 - 07/31/6
  
Title:
Performance Evaluation of Bilirubin Direct Gen.2 (BILD) - verification of standardization vs. manual Diazo Method
Source:
Roche Diagnostics
Role:
Principal Investigator
Dates:
05/25/11 - 11/14/12
Direct Funds:
$13,760
  
Title:
Redesign Children's Hospital Clinical Laboratory Space - Implementation of the Core Laboratory Concept
Role:
Director - assimilate collected information, design changes, oversee architectural redesign and instrument positioning
Dates:
1999 - 2000
  
Title:
A Clinical Evaluation of SureStep Pro Test Strips when used with High Hematocrit and High Glucose Neonate Blood Samples. SureStep Neonate Study, Protocol CR-DV-1023001
Source:
Lifescan Inc.
Role:
Principal Investigator
Dates:
12/13/2001 - 09/10/2002
Direct Funds:
$8,600
  
Title:
Reference Standards Laboratory
Source:
Contracts with Beckman Instruments, Inc., Ortho Clinical Diagnostics, Inc., Abbott Diagnostics, Roche Diagnostics, Dade Behring, Inc., College of American Pathologists, Siemens Diagnostics, and Olympus Diagnostics
Role:
Laboratory Director
Direct Funds:
$2,484,595 (total since 2001)
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
LO SF. Pediatric Clinical Chemistry. American Society for Clinical Laboratory Scientists - Wisconsin, Milwaukee, WI. April 2, 2014.
LO SF. Methylmalonic Aciduria. Autopsy Conference, Pathology Conference Room, Children's Hospital of Wisconsin. January 14, 1998
LO SF. Cobalamin Deficiency. Autopsy Conference, Pathology Conference Room, Children's Hospital of Wisconsin, May 13, 1998
LO SF. Pediatric Clinical Chemistry. Medical Technologist Senior Lecture Program. Marquette University, Milwaukee, WI. Annually since 1998.
LO SF. Thyroid Function Tests. Pediatric Endocrine Academic Conference, Children's Hospital of Wisconsin, Oct 13, 2006.
LO SF. Instrumentation for Endocrine Tests. Pediatric Endocrine Academic Conference, Children's Hospital of Wisconsin, Feb 16, 2007 and Mar 30, 2007
LO SF. Pediatric Clinical Chemistry. Clinical Laboratory Sciences Program, University of Wisconsin - Madison, May 7, 2007.
LO SF. Topics in Pediatric Clinical Chemistry. American Society for Clinical Laboratory Science - WI. Waukesha, WI. April 16, 2008
LO SF. Academic Medicine. Brookfield Academy Career Day, Brookfield, WI, March 15, 2013.
LO SF. Neonatal Bilirubin. Faculty Continuing Education Series, Children's Hospital of Wisconsin. January 15, 2014.
 
Regional
LO SF. Children's Reference Intervals. 2002 Wisconsin Ortho Clinical Diagnostics Customer Seminar, Country Inn & Hotel, October 22nd, Pewaukee WI.
LO SF. Children's Reference Intervals. 2002 Chicago Ortho Clinical Diagnostics Customer Seminar, October 23rd, Wyndham Hotel, Itasca, IL.
LO SF. Transcutaneous bilirubin measurements: Is it ready for clinical use? Clinical Pathology Conference, University of Minnesota, Feb 1, 2005.
LO SF. Pediatric Clinical Chemistry. ASCLS-WI State Convention, Country Springs Hotel Conference & Convention Center, Waukesha, WI, April 16, 2008.
LO SF. Laboratory medicine: what's new in the chemistry laboratory? Best Practices in Pediatrics, Wisconsin Dells, WI, March 7, 2009.
LO SF. Standardization in Clinical Chemistry. American Society for Clinical Laboratory Sciences National Meeting, Chicago, IL, July 30, 2014.
 
National
Miller G, Ashwood E, Killeen A, Horowitz G, Eckfeldt J, LO SF, et al. CAP proficiency testing using fresh frozen serum - effects on general chemistry analytes. 2004 AACC Annual Meeting, Los Angeles Convention Center, Los Angeles, July 27, 2004.
LO SF. Neonatal hyperbilirubinemia - Improving the laboratory's role. Clinical Laboratory Science Continuing Education Day, Ochsner Medical Center, New Orleans, LA, November 30, 2007.
LO SF. Enhancing the newborn screening programs: Inclusion of cystic fibrosis and lysosomal disorders - Newborn screening for cystic fibrosis and its impact on the clinical diagnostic laboratory. 2008 AACC Annual Meeting, Washington, D.C. July 29, 2008.
LO SF. Interactive cases in pediatric practice - Pondering problems in pediatrics. Short Course 2008 AACC Annual Meeting, Washington, D.C. July 30, 2008.
LO SF. Personalized medicine in pediatric neurology - Clinical pharmacogenetics in the treatment of new onset childhood epilepsy. Short Course 2010 AACC Annual Meeting, Los Angeles, CA, July 28, 2010.
LO SF. Laboratory Diagnosis of HIV - Should You Change Your Testing Algorithm? Short Course, 2013 AACC Annual Meeting, Houston, TX, July 30, 2013.
LO SF. Neonatal Bilirubin. AACC Southeast Section Meeting, Sandestin, FL, November 15, 2013.
LO SF. Newborn Screening. Midwest Association for Toxicology and Therapeutic Drug Monitoring Annual Meeting, Detroit, MI, April 4, 2014.
LO SF. Interactive cases in pediatric practice. Short Course. 2009 AACC Annual Meeting, Chicago, IL, July 20, 2009.
LO SF. Is Artificial Intelligence in Genomics Ready for Prime Time? Symposium. 2017 AACC Annual Scientific Meeting, San Diego, CA, July 31, 2017.
 
International
Doumas BT, LO SF, Ashwood E. The status of total and direct bilirubin measurements in neonatal and adult blood in U.S. laboratories. 18th International Congress of Clinical Chemistry and Laboratory Medicine, Kyoto, Japan, October 23, 2002.
LO SF. Humans cannot be measured by cows. 5th Athena Society Meeting, Hinitsa Bay, Greece, September 9, 2009.
LO SF. Neonatal Bilirubin - Are we any better at measuring it? 3rd Beijing Lab Medicine Forum in Women and Children's Health, Beijing, China, October 19, 2018.
LO SF. Traceability of bilirubin testing and its role in neonatal hyperbilirubinemia. 11th Asian-Pacific Congress of Clinical Biochemistry, Beijing, China, October 17, 2007
 

COMMITTEE SERVICE:
Medical College of Wisconsin
09/1998 - 08/2001 Member, Admissions Committee
09/2002 - 12/2002 Interviewer (ad hoc), Admissions Committee
01/2003 - 12/2006 Extended Member, Admissions Committee
07/2010 - 07/2016 Member (Secretary 2015/6), Faculty Benefits Committee
2016 - 2019 Member, Annual Faculty Staff Gift Drive Committee
 
Hospital
1997 - Present Member, ETT (Point of Care) Quality Control Task Force
1997 - 2008 Technical Director, Point of Care Oversight Committee
2004 - 2005 Consultant, RALS Implementation Committee
2007 - 2011 Member, Pharmacogenetics and Genomic Medicine, Steering Committee; Clinical and Clinical Laboratory Group; and Implementation Group
2008 - Present Acting Chair, Point of Care Testing Committee
2008 - Present Technical Director, Point of Care Operational Committee
2008 - 2010 Member, Finance Committee, Children's Specialty Group
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Resident and Fellow Education
01/17/11 - 01/31/11 Biochemical Genetics, Jessica Scott-Schwoerer, Genetics Fellowship
01/06/14 - 01/17/14 Biochemical Genetics, Gabrielle Geddes, Genetics Fellowship
03/30/15 - 04/10/15 Pediatric Chemistry, Stacy L. Hitt, Pediatric Pathology Fellowship
09/14/15 - 09/25/15 Biochemical Genetics, Randeep Brar, Genetics Fellowship
04/10/16 - 04/23/16 Pediatric Chemistry, Lauren Parsons, Pediatric Pathology Fellowship
1997 - 2007 Pediatric Clinical Chemistry in Pediatric Pathology Rotation
2004 - Present Pathology Residents, Chemistry Residency Training Program
2004 - 2009 Postdoctoral Training Program in Clinical Chemistry, Toxicology, Forensics and Molecular Diagnostics, 2-year program. Program currently not active
2005 - Present Pathology Residents, Pathology Review and Updates
2018 - Present Course-Director, Resident Chemistry, Pathology, Medical College of Wisconsin, Milwaukee, WI
 

COMMUNITY SERVICE ACTIVITIES:
2008 - 2019 Board of Directors, Brookfield Soccer Association, Brookfield, WI 53045
2009 - 2018 Club President, Elmbrook United Soccer Club (formerly Brookfield Soccer Association), Brookfield, WI 53045
2011 - 2014 Marketing Committee, Brookfield Academy, Brookfield, WI 53045
2014 - 2018 Education Committee, Brookfield Academy, Brookfield, WI 53045
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. LO SF, Yu Y, Yang DY, Liu HW. A colorimetric method for the estimation of 2-deoxy-3-C-methyl-branched sugars. Carbohydr. Res. 189:368, 1989.
2. Thorson JS, LO SF, Liu HW. Molecular basis of 3,6-dideoxyhexose biosynthesis: Elucidation of CDP-ascarylose biosynthetic genes and their relationship to other 3,6-dideoxyhexose pathways. J.A.C.S. 115:5827, 1993.
3. Thorson JS, LO SF, Liu HW, Hutchinson CR. Biosynthesis of 3,6-dideoxyhexoses: New mechanistic reflections upon 2,6-dideoxy, 4,6-dideoxy, and amino sugar construction. J.A.C.S. 115:6993, 1993.
4. Miller VP, Thorson JS, Ploux O, LO SF, Liu HW. Cofactor characterization and mechanistic studies of CDP-6-deoxy-3,4-glucoseen reductase: Exploration into a novel enzymatic C-O bond cleavage event. Biochemistry 32:11934, 1993.
5. LO SF, Miller VP, Lei Y, Thorson JS, Liu HW, Schottel JL. CDP-6-deoxy-3,4-glucoseen reductase gene: Enzyme purification and characterization. J. Bacteriology 176:460, 1994.
6. Thorson JS, LO SF, Ploux O, He XM, Liu HW. Studies of the biosynthesis of 3,6-dideoxyhexoses - Molecular cloning and characterization of the asc (ascarylose) region from yersinia pseudotuberculosis serogroup VA. J. Bacteriology 176:5483, 1994.
7. LO SF, Nahm MH, Parvin CA, Kessler G. Singleton versus duplicate prostate-specific antigen (PSA) measurements. Clin Chem 41:1535, 1995.
8. Parvin CA, LO SF, Deuser SM, Weaver BSN, Lewis LM, Scott MG. Impact of point-of-care testing on patient length of stay in a large emergency department. Clin Chem 42:711, 1996.
9. Matsumoto M, LO SF, Carruthers CJL, Min J, Mariathasan S, Plas D, Martin SM, Geha R, Nahm MH, Chaplin D. Affinity maturation without germinal centers in lymphotoxin- (Lt) deficient mice. Nature 382:462, 1996.
10. LO SF, Doumas BT, Ashwood ER. Performance of Bilirubin Determinations in US Laboratories - Revisited. Clin Chem 50: 190, 2004
11. VI Luzzi, AN Saunders, JW Koenig, J Turk, SF LO, UC Garg, D. Dietzen. Analytic Properties of Abused Drug Immunoassays Below Established Cutoff Values. Clin Chem. 50:717, 2004.
12. LO SF, Doumas BT, Ashwood ER. Proficiency testing for bilirubin determinations using specimens containing human serum and unconjugated bilirubin. Results of a College of American Pathologists Study. Arch. Path. Lab. Med. 128:1219, 2004.
13. LO SF, Jendrzejczak B, Doumas BT. Total or Neonatal bilirubin in the Vitros 5,1 FS assays? Hemoglobin interference, Hemolysis Index, Icterus Index. Clin Chem. 53; 799-800, 2007.
14. Miller WG, Myers G, Ashwood ER, Killeen AA, Wang E, Walsh M, Ehlers GW, Hassemer D, LO SF, Seccombe D, Siekmann L, Thienpont LM, Toth A, Umemoto M. State of the Art in Trueness and Inter-Laboratory Harmonization for 10 frequently measured analytes in Clinical Chemistry. Arch. Path. Lab. Med. 132:838-46, 2007.
15. Zidan H, LO SF, Wiebe D, Talano J, Alemzadeh R. Severe hypercholesterolemia mediated by lipoprotein X in a pediatric patient with chronic graft-versus-host disease of the liver. Pediatric Blood & Cancer. 50:1280-1, 2008.
16. LO SF, Jendrzejczak B, Doumas BT. Laboratory Performance in Neonatal Bilirubin Testing Using Commutable Specimens - A Progress Report on a College of American Pathologists Study. Arch. Path. Lab. Med. 132: 1781-1785, 2008.
17. Dietzen DJ, Rinaldo P, Whitley RJ, Rhead WJ, Hannon WH, Garg UC, LO SF, Bennett MJ. National Academy of Clinical Biochemistry: Laboratory Medicine Practice Guidelines. Follow Up Testing for Metabolic Diseases Identified by Expanded Newborn Screening Using Tandem Mass Spectrometry. Executive Summary. Clin Chem 55: 1615-1626, 2009.
18. LO SF, Kytzia H-j, Schumann G, Swartzentuber M, Vader HL, Weber F, Doumas BT. Interlaboratory comparison of the Doumas bilirubin reference method. Clin Biochem 42: 1328-1330, 2009.
19. LO SF, Jendrzejczak B, Doumas BT. Bovine serum-based bilirubin calibrators are inappropriate for some diazo methods. Clin Chem 56: 869-72, 2010.
20. Karon BS, Wickremasinghe AC, LO SF, Saenger AK, Cook WJ. BiliChek transcutaneous bilirubin meter overestimates serum bilirubin as measured by the Doumas reference method. Clin Biochem 43: 1009-1012, 2010.
21. LO SF and Doumas BT. Chapter. The Status of Bilirubin Measurements in U.S. Laboratories - Why is accuracy elusive? In Bhutani V (ed), Seminars in Perinatology - Newborn Jaundice Technologies. Philadelphia, PA. Elsevier Saunders; 35:141-7, 2011.
22. McDonagh AF, LO SF, Maisels MJ, and Watchko JF. Serum bilirubin measurements in hemolyzed samples. (letter) Clinica Chimica Acta 412: 1275, 2011.
23. Kahn SE, Astles JR, LO SF, Bennett MJ. AGREE II Instrument is Helpful for Creation of National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines. (letter) Clin Chem 2013 59: 446-7.
24. LO SF, Miller WG, and Doumas BT. Laboratory Performance in Albumin and Total Protein Measurement Using a Commutable Specimen - Results of a College of American Pathology Study. Arch Path Lab Med 2013 137: 912-20.
25. LO SF. Laboratory Accuracy in Neonatal Bilirubin: The Search for Truth in Laboratory Medicine. (Invited editorial) JAMA Pediatr 2016; 170:529-30. doi:10.1001/jamapediatrics.2016.0279.
26. Dietzen DJ, Bennett MJ, LO SF, Grey VL, Jones PM. Dried Blood Spot Reference Intervals for Steroids and Amino Acids in a Neonatal Cohort of the National Children's Study. Clin Chem 2016 62: 1658-67.
27. Colon -Franco JM, LO SF, Gourlay D, Drendel A, Lerner EB. Validation of a Hand-held Point of Care Device for Lactate in Adult and Pediatric Patients Using Traditional and Locally-smoothed Median and Maximum Absolute Difference Curves. Clin Chim Acta 2017 468: 145-9.
28. Wiencek JR, LO SF. Advances in the Diagnosis and Management of Cystic Fibrosis in the Genomic Era. [Epub ahead of print] Clin Chem February 7, 2018 as doi:10.11373.2017.274670.
 
Books, Chapters, and Reviews
1. LO SF. Urine Studies. In Fischbach F. & Dunning MB (eds). A Manual of Laboratory & Diagnostic Tests (7th Ed). Philadelphia, PA. Lippincott Williams & Wilkins; 2002.
2. LO SF. Chemistry Studies. In Fischbach F. & Dunning MB (eds). A Manual of Laboratory & Diagnostic Tests (7th Ed). Philadelphia, PA. Lippincott Williams & Wilkins; 2002.
3. Shi RZ, LO SF, Jin M, Schur BC, Stremski E, Wong SH. Clinical Toxicology-Pharmacogenomics as an adjunct for Interpretation of Drug Toxicity. In Wong SH, Linder MW, Valdes R Jr, Eds. Pharmacogenomics and Proteomics: Enabling the Practice of Personalized Medicine. Washington D.C., AACC Press; 2006: 283-294.
4. Kazmierczak S, Bhutani V, Gourley G, Kerr S, LO SF, Robertson A, Sena S. Transcutaneous bilirubin testing. In Nichols J, Ed. National Academy of Clinical Biochemistry: Laboratory Medicine Practice Guidelines. Evidence-based practice for point-of-care testing. Washington D.C., AACC Press; 2006:5-12.
5. LO SF. Chemistry Studies. In Fischbach F. & Dunning MB (eds). A Manual of Laboratory & Diagnostic Tests (8th Ed). Philadelphia, PA. Lippincott Williams & Wilkins; 2009.
6. Bennett MJ (chair), Rinaldo P, Whitley RJ, Rhead WJ, Hannon WH, Dietzen DJ, Garg UC, LO SF. National Academy of Clinical Biochemistry: Laboratory Medicine Practice Guidelines. Follow Up Testing for Metabolic Diseases Identified by Expanded Newborn Screening Using Tandem Mass Spectrometry. Washington, D.C., AACC Press; 2009.
7. LeGrys VA, Applequist R, Briscoe DR, Farrell P, Hickstein R, LO SF, Passarell R, Rheinheimer DW, Rosenstein BJ, and Vaks JE. CLSI. Sweat Testing: sample collection and quantitative chloride analysis; Approved guideline - Third edition. CLSI document C34-A3. Wayne, PA, Clinical and Laboratory Standards Institute, 2009.
8. LO SF, Young V, Rhead WJ. Identification of urine organic acids for the detection of inborn errors of metabolism using urease and gas chromatography-mass spectrometry (GC-MS). In Garg U and Hammett-Stabler CA (eds). Clinical Applications of Mass Spectrometry. New York, NY. Humana Press; 2010.
9. LO SF. In Dunning MB (ed). Nurses' Quick Reference to Common Laboratory & Diagnostic Tests, (5th ed). Philadelphia, Wolters Kluwer Lippincott Williams & Wilkins; 2011.
10. LO SF. Chapter 714. Laboratory testing in infants and children. In Behrman RE, Kliegman RM and Jenson HB (eds). Nelson Textbook of Pediatrics (19th Ed). Philadelphia, PA. WB Saunders; 2011.
11. LO SF. Chapter 715. Reference ranges for laboratory tests and procedures. In Behrman RE, Kliegman RM and Jenson HB (eds). Nelson Textbook of Pediatrics (19th Ed). Philadelphia, PA. WB Saunders; 2011.
12. Kallner A, Boyd JC, Duewer DL, Hatjimihail AT, Klee GG, LO SF, Pennello G, Sogin D, Tholen DW, Toman B, and White GH. CLSI. Expression of Measurement Uncertainty in Laboratory Medicine; Approved Guideline. CLSI document C51-A. Wayne, PA: Clinical and Laboratory Standards Institute; 2012.
13. LO SF. Chapter 9. Principles of basic techniques and laboratory safety. In Burtis CA, Ashwood ER, and Bruns DE (eds), Tietz Textbook of Clinical Chemistry and Molecular Diagnostics (5th Ed). Philadelphia, PA. Elsevier Saunders; 2012.
14. LO SF, Scott-Schwoerer JA, and Rhead WR. Chapter 3. Organic acid disorders. In Garg U, Smith, and Heese (eds). Inherited Metabolic Diseases, Washington D.C., AACC Press, 2012.
15. LO SF. In Dunning MB (ed). Nurses' Quick Reference to Common Laboratory & Diagnostic Tests, (6th ed). Philadelphia, PA. Wolters Kluwer Lippincott Williams & Wilkins; 2015.
16. LO SF. Chapter 8. Principles of Basic Technique and Laboratory Safety. In Burtis CA and Bruns DE (eds), Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics (7th Ed). Philadelphia, PA. Elsevier Saunders: 2015.
17. LO SF. Chapter 726. Laboratory testing in infants and children. In Kliegman RM, Stanton BF, St.Geme III J, and Schor N (eds). Nelson Textbook of Pediatrics (20th Ed). Philadelphia, PA. Elsevier; 2016.
18. LO SF. Chapter 727. Reference ranges for laboratory tests and procedures. In Kliegman RM, Stanton BF, St.Geme III J, and Schor N (eds). Nelson Textbook of Pediatrics (20th Ed). Philadelphia, PA. Elsevier; 2016.
19. Brown SM, LO SF. Chapter 42. Inborn Errors of Metabolism. In Clark W (ed), Contemporary Practice in Clinical Chemistry (3rd Ed). Washington D.C., AACC Press, 2016.
20. LO SF. Chapter 6. Cystic Fibrosis and Sweat Testing. In Jones P, Dietzen D, Haymond S, and Bennett B (eds). Pediatric Laboratory Medicine, New York, NY, McGraw-Hill, 2017.
21. LO SF. Chapter 2. Organic Acidemias. In Garg U and Smith LD (eds), Biomarkers in Inborn Errors of Metabolism: Clinical Aspects and Laboratory Determination. Philadelphia, PA. Elsevier Saunders: 2017.
22. LO SF. Chapter 12. Principles of basic techniques and laboratory safety. In Rifai N, Horvath R, and Wittwer C (eds), Tietz Textbook of Clinical Chemistry and Molecular Diagnostics (8th Ed). Philadelphia, PA. Elsevier Saunders; 2018.
23. Swinkels D, Cappellini N, LO SF. Chapter 38. Hemoglobin, iron and bilirubin. In Rifai N, Horvath R, and Wittwer C (eds). Tietz Textbook of Clinical Chemistry and Molecular Diagnostics (6th Ed). Philadelphia, PA. Elsevier Saunders; 2018.
24. Ellervik C, Swinkels D, Cappellini N, LO SF. Chapter 38. Hemoglobin, iron and bilirubin. In Rifai N, Horvath R, and Wittwer C (eds). Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics (8th Ed). Philadelphia, PA. Elsevier Saunders; 2019.
25. LO SF. Chapter 8. Principles of Basic Technique and Laboratory Safety. In Rifai N, Horvath R, and Wittwer C (eds), Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics (8th Ed). Philadelphia, PA. Elsevier Saunders: 2019.
 
Editorials, Letters to Editor, Other
1. LO SF, Human-based bilirubin challenge (discussion). In NB-A Participant Summary, CAP Surveys, 2003.
2. LO SF, Educational evaluation of total bilirubin results for specimen C-97 (discussion). In C-B Participant Summary, CAP Surveys, 2004.
3. LO SF, Educational evaluation of total bilirubin results for specimen NB-06 (discussion). In NB-B Participant Summary, CAP Surveys 2004.
4. LO SF, Pediatric reference ranges derived by different methodologies. In Baer DM, Ed. MLO Tips for the Clinical Experts. Nelson Publishing, 2006;Mar:47.
5. LO SF, Appropriateness of finger stick or capillary blood draw tubes for chemistry testing. In CAP TODAY, Q and A.2006;20: 90.
6. LO SF, Venipuncture-finger stick correlations. In Baer DM, Ed. MLO Tips for the Clinical Experts. Nelson Publishing, 2006. Submitted.
7. LO SF, Sweat chloride testing and the diagnosis of cystic fibrosis (discussion). In SW-A Participant Summary, CAP Surveys, 2007.
8. LO SF, Discontinuation of calculated TIBC and UIBC, and change in grading status for percent iron saturation (discussion). In C-B Participant Summary, CAP Surveys 2007.
9. LO SF, Educational grading of neonatal bilirubin results for specimen NB-06 (discussion). In NB-B Participant Summary, CAP Surveys, 2007.
10. LO SF, Educational grading of neonatal bilirubin results for specimen NB-11 (discussion). In NB-C Participant Summary, CAP Surveys, 2007.
11. LO SF, Pediatric reference ranges derived by different methodologies. In Baer DM, Ed. MLO Tips for the Clinical Experts. Nelson Publishing, 2007; Dec: 41.
12. LO SF, Screening for CF. In Baer DM, Ed. MLO Tips for the Clinical Experts. Nelson Publishing, 2008; Feb: 39.
13. LO SF, Educational grading of neonatal bilirubin results for specimen NB-02 (discussion). In NB-C Participant Summary, CAP Surveys, 2008.
14. Schneider R, LO SF. Critical values for total bilirubin in adults and children. In Baer DM, Ed. MLO Tips for the Clinical Experts. Nelson Publishing, 2008. Nov: 40.
15. LO SF, Educational grading of neonatal bilirubin results for specimen NB-12 (discussion). In NB-C/NB2-C Participant Summary, CAP Surveys, 2009.
16. LO SF. Is it necessary to protect all bilirubin specimens from light? In Karon BS, Ed. MLO Tips for the Clinical Experts. Nelson Publishing, 2010. Mar: 47.
17. LO SF, Educational grading of neonatal bilirubin results for specimen NB-02 (discussion). In NB-A/NB2-A Participant Summary, CAP Surveys, 2010.
18. LO SF, Sweat chloride testing (discussion). In SW-A Participant Summary, CAP Surveys, 2010.
19. LO SF, Revised reference intervals for sweat chloride interpretation (discussion). In SW-B Participant Summary, CAP Surveys, 2010.
20. LO SF, Educational grading of neonatal bilirubin results for specimen NB-02 (discussion). In NB-A/NB2-A Participant Summary, CAP Surveys, 2011.
21. LO SF, Educational grading of neonatal bilirubin results for specimen NB-06 (discussion). In NB-B/NB2-B Participant Summary, CAP Surveys, 2011.
22. LO SF, Educational grading of neonatal bilirubin results for specimen NB-12 (discussion). In NB-C/NB2-C Participant Summary, CAP Surveys, 2011.
23. Park J and LO SF, Revisions to Cystic Fibrosis Foundation guidelines (discussion). In SW-B Participant Summary, CAP Surveys, 2017.
24. LO SF, 2018 SW-A Supplemental question discussion (discussion). In SW-B Participant Summary, CAP Surveys, 2018.
 
Non-Refereed Journal Publications/Original Papers
1. LO SF, Kessler G. Prostate-specific antigen update. BJC-Laboratory Medicine Newsletter 3(3):1, 1995.
2. LO SF, Parvin CA, Scott MG. Impact of point-of-care testing on patient length of stay in a large emergency department. Proceedings of the 3rd International Symposium on Electrolytes and Blood Gases, AACC Press, 1997.
3. Zehnbauer B, LO SF, Radford D. Molecular testing for inherited breast cancer - Is it time? BJC-Laboratory Medicine Newsletter 4(5):1, 1997.
4. LO SF. Preanalytical variation. Heart Matters 5(2):3, 2002.
5. LO SF. Diagnosis of Neonatal Hyperbilirubinemia. Clinical Laboratory News 36(6):10-13, 2010.
6. LO SF. Cystic Fibrosis - How newborn screening algorithms detect disease. Clinical Laboratory News 37(10):10-12, 2011.
 
Abstracts
1. LO SF, Thorson JT, Liu HW. Cloning and sequence analysis of ascB and ascD, the genes coding for yersinia pseudotuberculosis CDP-D-glucose oxidoreductase (Eod) and CDP-6-deoxy- 3,4-glucoseen reductase (E3). Xth Midwest Enzyme Chemistry Conference, Loyola University, Chicago, IL, October 13, 1990.
2. Lei Y, Liu L, LO SF, Miller VP, Thorson JS, Weigel TM, Liu HW. Biosynthesis of 3,6-dideoxyhexoses: Exploration into the mechanism of CDP-ascarylose formation. 32nd ACS National Organic Chemistry Symposium, University of Minnesota, Minneapolis, MN June 16-20, 1991.
3. Miller VP, Weigel TM, Liu L, Russell RN, Thorson JS, Yu Y, LO SF, Liu HW. The biosynthesis of 3,6-dideoxyhexoses: Exploration of a novel enzymatic C-O bond cleavage event. XIth Midwest Enzyme Chemistry Conference, University of Illinois, Chicago, IL, October 12, 1991.
4. Thorson JS, LO SF, Yang DY, Lei Y, Liu HW. The biosynthesis of 3,6-dideoxy sugars: Enzyme purification, gene cloning, and mechanistic studies. XVIth International Carbohydrate Symposium, Paris-France, July 9, 1992.
5. Matsumoto M, Baranyay F, Nahm M, LO SF, Mariathasan S, Plas D, Geha R, Kanagawa O, Chaplin D. Isotype switching in the absence of germinal centers in peripheral lymphoid organs of lymphotoxin- deficient mice. Experimental Biology '95, Atlanta, GA, April 9-13, 1995.
6. LO SF, Liu HW. Cloning and characterization of the CDP-6-deoxy- 3,4-glucoseen reductase gene. XIIth Midwest Enzyme Chemistry Conference, The University of Chicago, Chicago, IL, October 10, 1992.
7. LO SF, Nahm MH, Parvin CA, Kessler G. Singleton versus duplicate prostate-specific antigen (PSA) measurements. The 1995 AACC Annual Meeting, Anaheim, CA, July 18, 1995.
8. Nahm MH, Park MK, McCourt D, LO SF, Irigoyen M, Diamond B, Sun Y. Antibodies to the capsular polysaccharide of S. Pneumoniae 6B serotype express the idiotype expressed by anti-DNA antibodies. 96th ASM General Meeting, New Orleans, LA, May 19-23, 1996.
9. Luzzi VI, Saunders AN, Koenig JW, Turk J, LO SF, Garg UC, Dietzen DJ. Incidence an analytic precision of abused drub detection below established cutoff concentrations. The 2003 AACC Annual Meeting, Philadelphia, PA, July 23, 2003. Clin Chem. 49:A80, 2003.
10. Myers GL, Miller WG, Ashwood ER, Killeen AA, Wang E, Ehlers GW, Hassemer DJ, LO SF, Seccombe DW, Siekmann L, Thienpont LM, Toth A, Umemoto M. Performance of Reference Measurement Procedures for the College of American Pathologists Fresh Frozen Serum Project. The 2004 AACC Annual Meeting, Los Angeles, CA, July 25-29, 2004. Clin Chem. 50:A107,2004
11. LO SF, Doumas BT. Effect of hemoglobin on the measurement of total (TBIL), unconjugated (Bu) and conjugated (Bc) bilirubins in the Fusion analyzer. The 2006 AACC Annual Meeting, Chicago, IL, July 23-27, 2006. Clin Chem. 52:A36,2006.
12. LO SF, Jendrzejczak B, Doumas BT. Interference of hyperlipidemia on chemistry tests performed on the Vitros analyzer. The 2007 AACC Annual Meeting, San Diego, CA, July 10-14, 2007. Clin Chem. 53:A122, 2007.
13. Young V, LO SF, Shoemaker J, Thomas A, Rhead WR. Validation and extension of the urease method for urine organic and amino acid analysis. The Society for Inherited Metabolic Disease 2008 Annual Meeting, Pacific Grove, CA, March 2-5, 2008. Molec Genet Metab 93:267, 2008.
14. LO SF, Schneider RJ, Jendrzejczak B, Hubbard L, Doumas BT. Pitfalls in the measurement of neonatal bilirubin. The 2008 AACC Annual Meeting, Washington, DC, July 20-24, 2008. Clin Chem 54:A229, 2008.
15. Young V, LO SF, Shoemaker J, Thomas A, Rhead WR. Validation and extension of the urease method for urine organic and amino acid analysis. Society for the Study of Inborn Errors of Metabolism 2008 Annual Symposium, Lisboa, Portugal, Sept 2-5, 2008. J Inherit Metab Dis 31 (Suppl 1);14, 2008
16. Colon-Franco JM, Drendel A, Gourlay D, LO SF, Lerner EB. Validation of a hand-held point of care device for lactate in adult and pediatric patients: analytical and clinical considerations for use in the pre-clinical setting. Clin Chem. 61:B-256, 2015
17. Lerner, EB, Drendel AL, Gourlay D, LO S, Colon-Franco JM. Comparison of Point-of-Care lactate values obtained using capillary or venous samples to laboratory values. SAEM19, May 14-17, 2019, Las Vegas, NV.
18. LO SF, Hubbard L, Korander M, Doumas B. Standardization of neonatal bilirubin testing and the lack of a primary reference material. The 2019 AACC Annual Scientific Meeting. Anaheim, CA Aug 4-8, 2019. Accepted.
19. NON-PEER REVIEWED ABSTRACTS
20. Shi R-Z, Jannetto PJ, Jing M, Schur BC, LO SF, Gock SB, Jentzen JM, Wong SH. CYP450 3A4 and 3A5 Genotyping in Methadone Intoxication Cases Using Pyrosequencing. The 9th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology, Louisville, KY, April 23-28th, 2005. Therapeutic Drug Monitoring, April 2005.
21. LO SF. Traceability of bilirubin testing and its role in neonatal hyperbilirubinemia. 11th Asian-Pacific Congress of Clinical Biochemistry, Beijing, China, October 14-19, 2007, Chinese Medical Journal 120 Suppl 2: 45 (S24-3), 2007.
22. Sander T, Noll L, Goodacre S, Le M, Hines R, LO S, North P. Analytical validation of a pharmacogenetic test for the epileptic population. MCW Research Day. Milwaukee, WI. Sept 16, 2009. and ASIP meeting April 2010.
 
Non-Peer Reviewed Educational Products
1. LO SF. Neonatal Hyperbilirubinemia. In Neonatal Bilirubin Survey (2007 NB-B), CAP Educational Activity, College of American Pathologists, 2007, 1-8. (CME/CE activity)
2. Allen K, LO SF, Sacks DB. Ketones. In Ketones Survey (2008 KET-B), CAP Educational Activity, College of American Pathologists, 2008, 1-8. (CME/CE activity)
3. LO SF. Learn why the NACB may be of interest to SYCL members. SYCL360 Podcast. June, 2012.