CURRICULUM VITAE
Stephanie S. Handler MD
Stephanie S. Handler MD
Associate Professor
Department of Pediatrics
Division of Cardiology
Department of Pediatrics
Division of Cardiology
OFFICE ADDRESS: |
Children’s Wisconsin - Milwaukee Hospital |
8915 W Connell Court |
Milwaukee, WI 53226 |
EDUCATION: |
08/01/2000 - 05/31/2004 BS, Vanderbilt University, Nashville, TN |
08/01/2004 - 05/31/2008 MD, Medical College of Wisconsin, Milwaukee, WI |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
07/01/2008 - 06/30/2011 Pediatric Residency, Pediatrics, Stanford University, Palo Alto, CA |
07/01/2011 - 06/30/2014 Pediatric Cardiology Fellowship, Pediatrics, Cardiology, Stanford University, Palo Alto, CA |
07/01/2014 - 06/30/2016 Pediatric Pulmonary Vascular Disease Fellowship, Pediatrics, Cardiology, Stanford University, Palo Alto, CA |
FACULTY APPOINTMENTS: |
07/01/2016 - Present Assistant Professor, Pediatrics, Pediatric Cardiology, Medical College of Wisconsin, 9000 W Wisconsin Ave, MS 713, Milwaukee, WI 53226 |
SPECIALTY BOARDS AND CERTIFICATION: |
Board Certified | Issue Date | Expiration |
Pediatrician | 2011 | None |
Pediatric Cardiologist | 2016 | None |
Licensure | Number | Issue Date | Expiration |
California Medical License | A109652 | 2008 | 2016 |
Wisconsin Medical License | 63875 | 2016 | None |
AWARDS AND HONORS: |
2000 - 2004 Academic Achievement Scholarship, Vanderbilt University |
2004 - Present Psi Chi Psychology Honor Society, Vanderbilt University |
2004 - Present Pi Delta Phi French Honor Society, Vanderbilt University |
2004 - Present Cum Laude, Vanderbilt University |
2005 - Present Best Medical Student Presentation, Midwest Pediatric Cardiology Conference |
2007 - Present Alpha Omega Alpha Medical Honor Society, Medical College of Wisconsin |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
2014 - Present American College of Cardiology (Fellow) |
2014 - 2016 Pediatric Cardiac Intensive Care Society (Member) |
2016 - Present Pulmonary Hypertension Association (Member) |
2016 - Present Pulmonary Vascular Research Institute (Member) |
2017 - Present National Pediatric Cardiology Quality Improvement Collaborative (Member) |
2017 - Present Pediatric Pulmonary Hypertension Network (Site Primary Investigator) |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorship |
2022 Frontiers in Pediatrics: Advances in the Care of the Pediatric Pulmonary Hypertension Patient: From the Neonate to the Adolescent-Young Adult Patient |
Ad-Hoc Reviewer |
2021 - Present The Journal of Thoracic and Cardiovascular Surgery |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2017 - Present Pediatric Residency Program Interviewer, Medical College of Wisconsin |
2017 - Present Physician Lead, Interstage Home Monitoring Program, Herma Heart Institute |
2018 - Present Physician Lead, Cardiac Insight Team, Herma Heart Institute |
2018 - Present Member, Critical Care Program Evaluation Committee, Medical College of Wisconsin |
2018 - Present Member, Quality Improvement Team, Herma Heart Institute |
2020 - Present Member, Pediatric Cardiology Fellowship Clinical Competency Committee, Medical College of Wisconsin |
2020 - Present Member, Pediatric Cardiology Program Evaluation Committee, Medical College of Wisconsin |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2012 - 2015 Member, Fellows-in-Training Council, American College of Cardiology |
2013 - 2015 Fellow Liaison, Pediatric Cardiac Intensive Care Society |
2013 - 2014 Chair, Fellows-in-Training Council, American College of Cardiology |
2014 - 2016 Member, Governance Task Force, American College of Cardiology |
2017 - 2020 Member, Partners in Quality Committee, American College of Cardiology |
2018 - 2020 Member, ACC Member Hub, American College of Cardiology |
2018 - Present Physician Co-Chair, Clinical Practice Committee, Pediatric Pulmonary Hypertension Network |
2020 - Present Physician Co-Leader, Unplanned Re-intervention Improvement Project, National Pediatric Cardiology Quality Improvement Collaborative |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
Local |
Handler SS, Pulmonary Hypertension: what the pediatrician needs to know, Children's Hospital CME, Milwaukee, WI, 11/2016 |
Handler SS, Block J, MIS-C: Diagnosis, Treatment and Outcomes (thus far). Best Practices in Pediatrics Special Edition: Moving Beyond COVID-19, Children’s Hospital CME, Milwaukee, WI, 10/2021 |
Regional |
Handler SS, VR in medical education - The Stanford Virtual Heart, Heart Summit, Milwaukee, WI, 10/2018 |
Handler SS, Decision Making and Management of the Borderline LV, Heart Summit, Milwaukee, WI, 10/2018 |
Handler SS, When is the left ventricle too small for biventricular palliation, Single Ventricle Morphology Course, Milwaukee, WI, 10/2019 |
Handler SS, Pediatric Pulmonary Hypertension, Grand Rounds, University of Chicago, Chicago, Il, 01/2021 |
National |
Handler SS, Therapies Aimed at Pulmonary Vascular Remodeling in the Single Ventricle, Stanford Single Ventricle Scientific Summit, Palo Alto, CA, 04/2019 |
Handler SS, Saudek DS, Understanding Outcomes to Inform Medical Decision Making, Cardiology 2021: 24th Annual Update on Pediatric and Congenital Cardiovascular Disease, Philadelphia, PA, 03/2021 |
Handler SS, Update on the National Pediatric Cardiology Quality Improvement Collaborative, 48th Annual Meeting, Congenital Heart Surgeons’ Society, Chicago, IL, 10/2021 |
Handler SS, Chan T, State of the Network: QI Project Learning to Date. Unplanned Reinterventions, National Pediatric Quality Improvement Collaborative, Virtual Learning Session, 04/2022 |
International |
Handler SS, Targeted Therapies in Single Ventricle Patients, 11th Pulmonary Vascular Research Institute Annual World Congress on Pulmonary Vascular Disease, Miami, FL, 01/2017 |
Handler SS, Prostanoids, 10th International Conference Neonatal and Childhood Pulmonary Vascular Disease, San Francisco, CA, 03/2017 |
Handler SS, Prostanoids, 11th International Conference Neonatal and Childhood Pulmonary Vascular Disease, San Francisco, CA, 03/2018 |
Handler SS, Congenital Heart Disease and PH - Novel Treatment Approaches, PHA International PH Conference & Scientific Sessions, Orlando, FL, 06/2018 |
Handler SS, Abman S, Coleman R, Nawaytou H, Career in Pediatric PH: Mentoring and Handler Advice. Session Moderator, UCSF 14th International Conference on Neonatal & Childhood Pulmonary Vascular Disease, San Francisco, CA, 03/2021 |
Handler SS, Berman-Rosenzweig E, Varghese N, PHuzzler Case Presentations: Session Moderator, UCSF 14th International Conference on Neonatal & Childhood Pulmonary Vascular Disease, San Francisco, CA, 03/2021 |
Handler SS, Varghese N, PHuzzler Case Presentations: Session Moderator, UCSF 15th International Conference on Neonatal & Childhood Pulmonary Vascular Disease, San Francisco, CA, 03/2022 |
Handler SS, Varghese N, Building An Inter-Disciplinary PH Program, UCSF 16th International Conference on Neonatal & Childhood Pulmonary Vascular Disease, San Francisco, CA, 03/2023 |
Handler SS, Varghese N, PHuzzler Case Presentations: Session Moderator, UCSF 16th International Conference on Neonatal & Childhood Pulmonary Vascular Disease, San Francisco, CA, 03/2023 |
Handler SS, Personalized or protocolized approach to pulmonary vein stenosis, 8th World Congress of Pediatric Cardiology and Cardiac Surgery, Washington DC, 08/2023 |
Handler SS, Therapeutic Updates Workshop, PH Therapies: Session Moderator, UCSF 17th International Conference on Neonatal & Childhood Pulmonary Vascular Disease, San Francisco, CA, 02/2024 |
Handler SS, Varghese N, PHuzzler Case Presentations: Session Moderator, UCSF 17th International Conference on Neonatal & Childhood Pulmonary Vascular Disease, San Francisco, CA, 02/2024 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
Regional |
Jaquiss RD, Siehr SL, Ghanayem NS, Hoffman GM, Fedderly RT, Cava JR, Mussatto KA, Tweddell JS, Early cavopulmonary anastomosis after Norwood procedure results in excellent Fontan outcome, Midwest Pediatric Cardiology Society Annual Meeting., Des Moines, IA, 09/2005 |
Jaquiss RD, Siehr SL, Ghanayem NS, Hoffman GM, Fedderly RT, Cava JR, Mussatto KA, Tweddell JS, Early cavopulmonary anastomosis after Norwood procedure results in excellent Fontan outcome, 37th Annual Midwest Student Biomedical Research Forum, Lincoln, NE, 01/2006 |
Handler SS, Hallis BJ, Tillman KA, Krolikowski M, Kuhn EM, Kirkpatrick EC, Brosig CL, Assessment of Quality of Life in Pediatric Patient with Pulmonary Hypertension, Midwest Pediatric Cardiology Society Annual Meeting, St Louis, MO, 12/2017 |
Raskin A, Lagatta J, Mitchell M, Handler SS, Influence of Pulmonary Hypertension on Surgical PDA Ligation Outcomes in Preterm Neonates, Midwest Pediatric Cardiology Society Annual Meeting, Rochester, MN, 09/2018 |
Kieu V, Sumski C, Cohen S, Reinhardt E, Axelrod DM, Handler SS, The Impact of Virtual Reality Learning on Transition Education in Adolescents with Congenital Heart Disease, Midwest Pediatric Cardiology Conference, Des Moines, IA, 09/2021 |
Mansukhani SA, Visotcky A, Sparapani R, Rudd NA, Handler S, Frommelt M., Implementation of a Post-operative Clinical Pathway for Patients Following Norwood Procedure, Midwest Pediatric Cardiology Conference, Des Moines, IA, 09/2021 |
Henning RE, Blonsky SE, Handler SS, Axelrod DM, Lowery R, Owens ST, Virtual Reality Curriculum Enhances Congenital Heart Disease Medical Education., Midwest Pediatric Cardiology Conference, Des Moines, IA, 09/2021 |
Rauscher J, Rudd N, Handler S, Tanem J, Scott A, Frommelt M, Utilization and Management of Gastrostomy Tubes in Norwood Infants through One Year of Age: A Single-Center Review of Practice, Midwest Pediatric Cardiology Conference, Des Moines, IA, 09/2021 |
Rudd N, Scott A, Baillie D, Hyland H, Kroll K, Bagli S, Frommelt M, Handler SS, Quality Improvement Initiatives Promote Tummy Time Therapy for Infants in the Cardiac Intensive Care Unit, Midwest Pediatric Cardiology Conference, Des Moines, IA, 09/2021 |
National |
Siehr SL, Feinstein JA, Yang W, Penn LF, Ogawa MT Ramamoorthy C, Hemodynamic Effects of Phenylephrine, Vasopressin, and Epinephrine in Children with Pulmonary Hypertension: A Pilot Study, Cardiology 2014: 17th Annual Update on Pediatric and Congenital Cardiovascular Disease, Orlando, FL, 02/2014 |
Siehr SL, Shi S, Hu Z, Jin B, Hanley FL, Reddy VM, McElhinney DB, Ling XB, Shin AY, Exploring the role of polycythemia in patients with cyanosis after palliative congenital heart surgery, 63rd Annual Scientific Session & Expo of the American College of Cardiology, Washington, DC, 03/2014 |
Wilson HC, Lim TR, Axelrod DM, Werho DK, Handler SS, Mullan PB, Cooke JM, Owens, ST, Development and Validation of a Multimedia Pediatric Cardiology Assessment Tool for Pediatric Resident Trainees., American Academy of Pediatrics National Conference & Exhibition, New Orleans, LA, 10/2019 |
Rudd N, Frontier K, Handler SS, Implementation of a Pre-operative Feeding Pathway in Ductal Dependent Congenital Heart Disease, NPC-QIC Learning Session, Ann Arbor, MI, 11/2019 |
Sun H, Ivy DD, Stockbridge N, Handler SS, Bates A, Krishnan U, Yung D, Hopper RK, Fineman J, Varghese NP, Austin ED, Avitabile C, Freire G, Mullen MP, Utilizing Actigraphy to Measure Impact of Genetic Mutations on Heart Rate Variability in Pediatric Pulmonary Arterial Hypertension., American Thoracic Society, San Francisco, CA, 06/2020 |
Wilson HC, Lim TR, Axelrod DM, Werho DK, Handler SS, Mullan PB, Cooke JM, Owens ST, Virtual Reality Curriculum Increases Pediatric Residents’ Knowledge and Ability to Diagnose Congenital Heart Defects, American Academy of Pediatric National Conference & Exhibition, San Diego, CA, 10/2020 |
Sullivan R, Handler SS, Chen S, Feinstein JA, The role of subcutaneous treprostinil after stage 1 and 2 single ventricle palliation. Single Ventricle Investigator Meeting, Single Ventricle Investigator Meeting, Palo Alto, CA, 03/2021 |
Handler SS, Frommelt P, Bertrandt RA, Niebler R, Thompson NE, Scott JP, Wakeham MK, Szadkowski A, Kim FY, Hoffman GM, Distribution of Cardiac Power Indices Following the Norwood Procedure, Annual Scientific Session & Expo of the American College of Cardiology, Washington, DC, 04/2021 |
Blonsky SE, Henning RE, Masterson EM, Axelrod DM, Handler SS, Yu S, Owens ST, Virtual Reality Curriculum Increases Pediatric Clerkship Students’ Knowledge of Congenital Heart Disease, Pediatric Academic Societies Meeting, Denver, CO, 04/2022 |
Tillman K, Handler SS, Cramer J, Kirkpatrick E, Single-Center Experience in the Administration of Ambrisentan Solution to Pediatric Patients with Pulmonary Hypertension, Cardiology 2024: 27th Annual Update on Pediatric and Congenital Cardiovascular Disease, Scottsdale, AZ, 02/2024 |
Baker K, Heisler R, Froh M, Pladies S, Rauscher J, Rudd N, Scott A, Tanem J, Handler SS, Single-Center Review of Energy and Nutrient Dense Formula in Infants with Congenital Heart Disease, Cardiology 2024: 27th Annual Update on Pediatric and Congenital Cardiovascular Disease, Scottsdale, AZ, 02/2024 |
Tanem J, Rudd N, Scott A, Rauscher J, Handler SS, Outcomes from 20 years of Interstage Home Monitoring, Cardiology 2024: 27th Annual Update on Pediatric and Congenital Cardiovascular Disease, Scottsdale, AZ, 02/2024 |
International |
Siehr SL, Stuth E, Tweddell JS, Hoffman GM, Troshynski T, Jones D, Mitchell M, Ghanayem NS, Hypersensitivity Reactions to Aprotinin Reexposure in Pediatric Surgery, 22nd Annual European Association of Cardiothoracic Surgery Society Conference, Lisbon, Portugal, 09/2008 |
Siehr SL, Ivy DD, Miller-Reed K, Ogawa M, Rosenthal DN, Feinstein JA, Children with pulmonary arterial hypertension and prostanoid therapy: long-term hemodynamics, 31st Annual Meeting & Scientific Session of the International Society for Heart and Lung Transplantation, San Diego, CA, 04/2011 |
Siehr SL, Martin MH, Axelrod D, Efron B, Peng L, Roth SJ, Perry S, Shin AY, Outcomes following cardiac catheterization after congenital heart surgery, 9th International Conference of The Pediatric Cardiac Intensive Care Society, Miami, FL, 12/2012 |
Siehr SL, Bernstein D, Yeh J, Berry GJ, Rosenthal DN, Hollander SA, Orthotopic heart transplantation in two infants with histiocytoid cardiomyopathy and left ventricular non-compaction, 33rd Annual Meeting & Scientific Session of the International Society for Heart and Lung Transplantation, Montreal Canada, 04/2013 |
Siehr SL, Feinstein JA, Yang W, Penn LF, Ogawa MT, Hemodynamic Effects of Phenylephrine, Vasopressin, and Epinephrine in Children with Pulmonary Hypertension: A Pilot Study, European Society for Paediatric Anaesthesiology Annual Congress., Geneva, Switzerland, 12/2013 |
Siehr SL, Hollander SA, Rosenthal D, Gauvreau K, Almond CA, Evaluating Pediatric Heart Re-transplant Candidates: Using a Risk Prediction Model to Estimate Early Mortality after Re-Transplant, 34th Annual Meeting & Scientific Session of the International Society for Heart and Lung Transplantation, San Diego, CA, 04/2014 |
Handler SS, Ogawa MT, Hopper RK, Sakarovitch C, Feinstein JA, Subcutaneous treprostinil in pediatric patients with failing single-ventricle physiology, 36th Annual Meeting & Scientific Session of the International Society for Heart and Lung Transplantation, Washington, DC, 04/2016 |
Sullivan R, Gerardin J, Handler SS, Novel use of selexipag for treatment of severe cyanosis in a patient with unilateral pulmonary arteriovenous malformations after the Fontan procedure, 13th International Conference Neonatal and Childhood Pulmonary Vascular Disease, San Francisco, CA, 03/2020 |
Krishnan S, Files M, Tjoeng Y, Otero Luna A, Handler S, Lay A, Chan T, Incidence, Risk Factors and Outcomes for Infants Requiring Unplanned Reintervention after Stage 2 Palliation for Single Ventricle Heart Disease, 8th World Congress of Pediatric Cardiology and Cardiac Surgery, Washington, DC, 08/2023 |
Rudd N, Tanem J, Scott A, Rauscher J, Baker K, Saudek D, Handler S, Positive Developmental Care Trends in Hypoplastic Left Heart Syndrome Patients with High-Risk Characteristics Undergoing Hybrid Procedure, 8th World Congress of Pediatric Cardiology and Cardiac Surgery, Washington DC, 08/2023 |
Kirkpatrick EC, Afolayan J, Handler SS, Liegl M, Pan A, Circulating Levels of Bone Morphogenic Protein 7 and C-terminus of hsc70-interacting protein are Elevated in Pediatric Pulmonary Hypertension, 17th International Conference Neonatal and Childhood Pulmonary Vascular Disease, San Francisco, CA, 02/2024 |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Caicedo L, Hopper RK, Garcia H, Ivy DD, Haag D, Fineman J, Humpi T, Al-Tamimi O, Feinstein J, Berger RM, Berman-Rosenzweig E, Kashour T, Diaz GF, Mendoza A, Bobhate P, Handler S, Lopes AA, Barwad P, Kumar Rahit M, Krishnan U, Adatia ITK, Moledina S, Abman S, Cerro Marin MJD. EXPRESS: Acute Vasoreactivity Testing in Pediatric Idiopathic Pulmonary Arterial Hypertension: an international Survey on Current Practice. Pulm Circ. 2019 May 30;9(4):2045894019857533. PMCID: PMC6886286 |
2. Truong DT, Trachtenberg FL, Pearson GD, Dionne A, Elias MD, Friedman K, Hayes KH, Mahony L, McCrindle BW, Oster ME, Pemberton V, Powell AJ, Russell MW, Shekerdemian LS, Son MB, Taylor M, Newburger JW, MUSIC Study Investigators (Supplement 1). The NHLBI Study on Long-terM OUtcomes after the Multisystem Inflammatory Syndrome In Children (MUSIC): Design and Objectives. Am Heart J. 2022 Jan;243:43-53. PMCID: PMC8710361 |
3. Jaquiss RD, Siehr SL, Ghanayem NS, Hoffman GM, Fedderly RT, Cava JR, Mussatto KA, Tweddell JS. Early cavopulmonary anastomosis after Norwood procedure results in excellent Fontan outcome. Ann Thorac Surg. 2006 Oct;82(4):1260-5; discussion 1265-6. |
4. Siehr S, Stuth E, Tweddell J, Hoffman G, Troshynski T, Jones D, Mitchell M, Ghanayem N. Hypersensitivity reactions to aprotinin re-exposure in paediatric surgery. Eur J Cardiothorac Surg. 2010 Feb;37(2):307-11. |
5. Chin C, Chen G, Sequeria F, Berry G, Siehr S, Bernstein D, Rosenthal D, Reinhartz O, Tyan D. Clinical usefulness of a novel C1q assay to detect immunoglobulin G antibodies capable of fixing complement in sensitized pediatric heart transplant patients. J Heart Lung Transplant. 2011 Feb;30(2):158-63. |
6. Hill AC, Maxey DM, Rosenthal DN, Siehr SL, Hollander SA, Feinstein JA, Dubin AM. Electrical and mechanical dyssynchrony in pediatric pulmonary hypertension. J Heart Lung Transplant. 2012 Aug;31(8):825-30. |
7. Siehr SL, Ivy DD, Miller-Reed K, Ogawa M, Rosenthal DN, Feinstein JA. Children with pulmonary arterial hypertension and prostanoid therapy: long-term hemodynamics. J Heart Lung Transplant. 2013 May;32(5):546-52. PMCID: PMC3760159 |
8. Siehr SL, Norris JK, Bushnell JA, Ramamoorthy C, Reddy VM, Hanley FL, Wright GE. Home monitoring program reduces interstage mortality after the modified Norwood procedure. J Thorac Cardiovasc Surg. 2014 Feb;147(2):718-23.e1. |
9. Siehr SL, Hanley FL, Reddy VM, Miyake CY, Dubin AM. Incidence and risk factors of complete atrioventricular block after operative ventricular septal defect repair. Congenit Heart Dis. 2014;9(3):211-5. |
10. Siehr SL, Bernstein D, Yeh J, Berry GJ, Rosenthal DN, Hollander SA. Orthotopic heart transplantation in two infants with histiocytoid cardiomyopathy and left ventricular non-compaction. Pediatr Transplant. 2013 Nov;17(7):E165-7. |
11. Siehr SL, Martin MH, Axelrod D, Efron B, Peng L, Roth SJ, Perry S, Shin AY. Outcomes following cardiac catheterization after congenital heart surgery. Catheter Cardiovasc Interv. 2014 Oct 01;84(4):622-8. |
12. Siehr SL, Punn R, Priest JR, Lowenthal A. Ebstein anomaly and Trisomy 21: A rare association. Ann Pediatr Cardiol. 2014 Jan;7(1):67-9. PMCID: PMC3959069 |
13. Siehr SL, McCarthy EK, Ogawa MT, Feinstein JA. Reported sildenafil side effects in pediatric pulmonary hypertension patients. Front Pediatr. 2015;3:12. PMCID: PMC4353247 |
14. Sinha SS, Julien HM, Krim SR, Ijioma NN, Baron SJ, Rock AJ, Siehr SL, Cullen MW, American College of Cardiology Fellow-in-Training Section Leadership Council. COCATS 4: Securing the Future of Cardiovascular Medicine. J Am Coll Cardiol. 2015 May 05;65(17):1907-14. |
15. Siehr SL, Maeda K, Connolly AA, Tacy TA, Reddy VM, Hanley FL, Perry SB, Wright GE. Mitral Stenosis and Aortic Atresia--A Risk Factor for Mortality After the Modified Norwood Operation in Hypoplastic Left Heart Syndrome. Ann Thorac Surg. 2016 Jan;101(1):162-7. |
16. Anand V, Kwiatkowski DM, Ghanayem NS, Axelrod DM, DiNardo J, Klugman D, Krishnamurthy G, Siehr S, Stromberg D, Yates AR, Roth SJ, Cooper DS. Training Pathways in Pediatric Cardiac Intensive Care: Proceedings From the 10th International Conference of the Pediatric Cardiac Intensive Care Society. World J Pediatr Congenit Heart Surg. 2016 Jan;7(1):81-8. |
17. Siehr SL, Shi S, Hao S, Hu Z, Jin B, Hanley F, Reddy VM, McElhinney DB, Ling XB, Shin AY. Exploring the Role of Polycythemia in Patients With Cyanosis After Palliative Congenital Heart Surgery. Pediatr Crit Care Med. 2016 Mar;17(3):216-22. |
18. Siehr SL, Feinstein JA, Yang W, Peng LF, Ogawa MT, Ramamoorthy C. Hemodynamic Effects of Phenylephrine, Vasopressin, and Epinephrine in Children With Pulmonary Hypertension: A Pilot Study. Pediatr Crit Care Med. 2016 May;17(5):428-37. |
19. Handler SS, Ogawa MT, Hopper RK, Sakarovitch C, Feinstein JA. Subcutaneous treprostinil in pediatric patients with failing single-ventricle physiology. J Heart Lung Transplant. 2017 Sep 14. |
20. Handler SS, Ginde S, Bergstrom CP, Woods RK. Tetralogy of fallot with and without pulmonary atresia Critical Heart Disease in Infants and Children. 1 January 2018:705-719.e4. |
21. Kirkpatrick EC, Handler SS, Foerster S, Gudausky T, Tillman K, Mitchell M. Single center experience with the Potts shunt in severe pulmonary arterial hypertension Progress in Pediatric Cardiology. March 2018;48:111-115. |
22. Handler SS, Buelow M, Bergstrom C, Frommelt PC, Hraska V. Hybrid Palliation as a Bridge to Biventricular Repair in Critical Aortic Stenosis With Coarctation. Ann Thorac Surg. 2019 Jun;107(6):e395-e396. |
23. Handler SS, Hallis BJ, Tillman KA, Krolikowski M, Kuhn EM, Kirkpatrick EC, Brosig CL. Assessment of quality of life in pediatric patients with pulmonary hypertension. Pulm Circ. 2019;9(3):2045894018822985. PMCID: PMC6607578 |
24. Edwards JJ, Murali C, Pogoriler J, Frank DB, Handler SS, Deardorff MA, Hopper RK. Histopathologic and Genetic Features of Alveolar Capillary Dysplasia with Atypical Late Presentation and Prolonged Survival. J Pediatr. 2019 Jul;210:214-219.e2. PMCID: PMC6592752 |
25. Caicedo L, Hopper R, Garcia Aguilar H, Ivy D, Haag D, Fineman J, Humpl T, Al-Tamimi O, Feinstein JA, Berger R, Rosenzweig E, Kashour T, Diaz GF, Mendoza A, Krishnan U, Bobhate P, Handler S, Lopes AA, Kumar Rahit M, Barward P, Labrandero de Lera C, Adatia I, Moledina S, Abman S, Cerro MJd. Acute vasoreactivity testing in pediatric idiopathic pulmonary arterial hypertension: an international survey on current practice Pulmonary Circulation. October 2019;9(4). |
26. Reddy S, Handler SS, Wu S, Rabinovitch M, Wright G. Proceedings From the 2019 Stanford Single Ventricle Scientific Summit: Advancing Science for Single Ventricle Patients: From Discovery to Clinical Applications. J Am Heart Assoc. 2020 Apr 07;9(7):e015871. PMCID: PMC7428620 |
27. Sachdeva S, Kuhn E, Frommelt PC, Handler S. Role of echocardiographic scoring systems in predicting successful biventricular versus univentricular palliation in neonates with critical aortic stenosis. Cardiol Young. 2020 Nov;30(11):1702-1707. |
28. Sullivan RT, Tillman KA, Kindel SJ, Handler SS. Diazoxide-associated pulmonary hypertension in a patient with noncompaction cardiomyopathy. Pulm Circ. 2021;11(1):2045894020987117. PMCID: PMC7869162 |
29. Callan EA, Geddes G, Konduri GG, Handler S. A Case of Alveolar Capillary Dysplasia with Misalignment of the Pulmonary Veins (ACD/MPV): The Importance of Early Genetic Testing Journal of Neonatology. March 2021;35(1):38-41. |
30. Cramer J, Bevry M, Handler S, Tillman K, Abourashed EA. Stability Determination of an Extemporaneously Compounded Ambrisentan Suspension by High Performance Liquid Chromatography Analysis. J Pediatr Pharmacol Ther. 2021;26(3):265-270. PMCID: PMC8021248 |
31. McLennan DI, Solano ECR, Handler SS, Lincoln J, Mitchell ME, Kirkpatrick EC. Pulmonary Vein Stenosis: Moving From Past Pessimism to Future Optimism. Front Pediatr. 2021;9:747812. PMCID: PMC8524035 |
32. Rosenzweig EB, Bates A, Mullen MP, Abman SH, Austin ED, Everett A, Fineman J, Feinstein J, Hopper RK, Kinsella JP, Krishnan US, Lu M, Mandl KD, Raj JU, Varghese N, Yung D, Handler SS, Sleeper LA. Cardiac Catheterization and Hemodynamics in a Multicenter Cohort of Children with Pulmonary Hypertension. Ann Am Thorac Soc. 2022 Jun;19(6):1000-1012. PMCID: PMC9169121 |
33. Luna AO, Kuhnell P, Wooton S, Handler SS, Wright G, Hammel J, Tweddell JS, Chan T. Factors Associated with Inability to Discharge After Stage 1 Palliation for Single Ventricle Heart Disease: An Analysis of the National Pediatric Cardiology Quality Improvement Collaborative Database. Pediatr Cardiol. 2022 Aug;43(6):1298-1310. |
34. Handler SS, Varghese NP, Rosenzweig EB, Yung D, Krishnan U, Whalen E, Bates A, Avitabile CM, Jackson EO, Hirsch R, Fineman J, Abman SH. Building a dedicated pediatric pulmonary hypertension program: A consensus statement from the pediatric pulmonary hypertension network Pulmonary Circulation. January 2022;12(1). |
35. Lim TR, Wilson HC, Axelrod DM, Werho DK, Handler SS, Yu S, Afton K, Lowery R, Mullan PB, Cooke J, Owens ST. Virtual reality curriculum increases paediatric residents' knowledge of CHDs. Cardiol Young. 2023 Mar;33(3):410-414. |
36. Wilson HC, Lim TR, Axelrod DM, Werho DK, Handler SS, Mullan PB, Cooke JM, Owens ST. A multimedia paediatric cardiology assessment tool for medical students and general paediatric trainees: development and validation. Cardiol Young. 2023 Mar;33(3):444-448. |
37. Handler SS, Varghese NP, Rosenzweig EB, Yung D, Krishnan U, Whalen E, Bates A, Avitabile CM, Jackson EO, Hirsch R, Fineman J, Abman SH, Pediatric Pulmonary Hypertension Network (PPHNet). Building a dedicated pediatric pulmonary hypertension program: A consensus statement from the pediatric pulmonary hypertension network. Pulm Circ. 2022 Jan;12(1):e12031. PMCID: PMC9052968 |
38. Siehr SL, Ogawa M, Romfh A, Rosenthal DN, Feinstein JA. Outpatient Subcutaneous Treprostinil for Pediatric Single Ventricle Patients The Journal of Heart and Lung Transplantation. |
39. Handler SS, Feinstein JA. Pulmonary Vascular Disease in the Single-Ventricle Patient: Is it Really Pulmonary Hypertension and if So, How and When Should We Treat it? Advances in Pulmonary Hypertension. . |
40. Anfinson M, Fitts RH, Lough JW, James JM, Simpson PM, Handler SS, Mitchell ME, Tomita-Mitchell A. Significance of α-Myosin Heavy Chain (<i>MYH6</i>) Variants in Hypoplastic Left Heart Syndrome and Related Cardiovascular Diseases. J Cardiovasc Dev Dis. 2022 May 03;9(5). PMCID: PMC9147009 |
41. Clark B, Froh M, Karls C, Feuling MB, Goday P, Uhing M, Handler SS, Nghiem-Rao TH, Polzin E. Assessing growth of infants with chylothorax receiving fortified skimmed human breast milk. Nutr Clin Pract. 2023 Feb;38(1):199-203. PMCID: PMC10448868 |
42. Handler SS, Jin J, Ogawa MT, Feinstein JA, Lo C. Abnormal platelet aggregation in pediatric pulmonary hypertension. Pulm Circ. 2022 Jul;12(3):e12104. PMCID: PMC9294293 |
43. Sullivan RT, Handler SS, Feinstein JA, Ogawa M, Liu E, Ma M, Hopper RK, Norris J, Hollander SA, Chen S. Subcutaneous Treprostinil Improves Surgical Candidacy for Next Stage Palliation in Single Ventricle Patients With High-Risk Hemodynamics. Semin Thorac Cardiovasc Surg. 2023 Winter;35(4):733-743. |
44. Ellepola CD, Handler SS, Frommelt M, Saudek DE, Scott J, Hoffman G, Frommelt PC. Intranasal dexmedetomidine for transthoracic echocardiography in infants with shunt-dependent single ventricle heart disease. Cardiol Young. 2023 Aug;33(8):1327-1331. |
45. Hopper RK, Abman SH, Elia EG, Avitabile CM, Yung D, Mullen MP, Austin ED, Bates A, Handler SS, Feinstein JA, Ivy DD, Kinsella JP, Mandl KD, Raj JU, Sleeper LA, Pediatric Pulmonary Hypertension Network Investigators. Pulmonary Hypertension in Children with Down Syndrome: Results from the Pediatric Pulmonary Hypertension Network Registry. J Pediatr. 2023 Jan;252:131-140.e3. PMCID: PMC10195185 |
46. Segar DE, Pan AY, McLennan DI, Kindel SJ, Handler SS, Ginde S, Woods RK, Goot BH, Spearman AD. Clinical Variables Associated with Pre-Fontan Aortopulmonary Collateral Burden. Pediatr Cardiol. 2023 Jan;44(1):228-236. PMCID: PMC10155213 |
47. Handler SS, Chan T, Ghanayem NS, Rudd N, Wright G, Visotcky A, Sparapani R, Mitchell ME, Hoffman GM, Frommelt MA. Impact of Reintervention During Stage 1 Palliation Hospitalization: A National, Multicenter Study. Ann Thorac Surg. 2023 Apr;115(4):975-981. |
48. Konkel T, Kroll KH, Goertz MT, Lavoie J, Bagli SP, Kogutkiewicz K, Kostroski R, Scott L, Stoll P, Andres J, Saudek D, Handler SS, Brosig CL. Screening for traumatic stress in children and adolescents with congenital heart disease Progress in Pediatric Cardiology. March 2023;68. |
49. Elias MD, Truong DT, Oster ME, Trachtenberg FL, Mu X, Jone PN, Mitchell EC, Dummer KB, Sexson Tejtel SK, Osakwe O, Thacker D, Su JA, Bradford TT, Burns KM, Campbell MJ, Connors TJ, D'Addese L, Forsha D, Frosch OH, Giglia TM, Goodell LR, Handler SS, Hasbani K, Hebson C, Krishnan A, Lang SM, McCrindle BW, McHugh KE, Morgan LM, Payne RM, Sabati A, Sagiv E, Sanil Y, Serrano F, Newburger JW, Dionne A, Pediatric Heart Network MUSIC Study Investigators. Examination of Adverse Reactions After COVID-19 Vaccination Among Patients With a History of Multisystem Inflammatory Syndrome in Children. JAMA Netw Open. 2023 Jan 03;6(1):e2248987. PMCID: PMC9857632 |
50. Clark B, Froh M, Karls C, Feuling MB, Goday P, Uhing M, Handler SS, Nghiem-Rao TH, Polzin E. Assessing growth of infants with chylothorax receiving fortified skimmed human breast milk. Nutr Clin Pract. 2023 Feb;38(1):199-203. PMCID: PMC10448868 |
51. Youssef DE, Handler SS, Richards SM, Sheppard CA, Smith J, Tillman K, Pietrosanu M, Kirkpatrick E, Bates A. Multicenter review of a tadalafil suspension formulation for infants and children with pulmonary hypertension: A North American experience. Front Pediatr. 2023;11:1055131. PMCID: PMC9909267 |
52. Avitabile CM, Yung D, Handler S, Hopper RK, Fineman J, Freire G, Varghese N, Mullen MP, Krishnan US, Austin E, Silveira L, Ivy DD. Measurement of Physical Activity by Actigraphy in Infants and Young Children with Pulmonary Arterial Hypertension. J Pediatr. 2023 Nov;262:113639. |
53. Avitabile CM, Hopper RK, Handler SS, Bates A. Editorial: Advances in the care of the pediatric pulmonary hypertension patient: from the neonate to the adolescent-young adult patient. Front Pediatr. 2023;11:1220070. PMCID: PMC10248507 |
54. Kieu V, Sumski C, Cohen S, Reinhardt E, Axelrod DM, Handler SS. The Use of Virtual Reality Learning on Transition Education in Adolescents with Congenital Heart Disease. Pediatr Cardiol. 2023 Dec;44(8):1856-1860. |
55. Collaco JM, Abman SH, Austin ED, Avitabile CM, Bates A, Fineman JR, Freire GA, Handler SS, Ivy DD, Krishnan US, Mullen MP, Varghese NP, Yung D, Nies MK, Everett AD, Zimmerman KO, Simmons W, Chakraborty H, Yenokyan G, Newell-Sturdivant A, Christensen E, Eyzaguirre LM, Hanley DF, Rosenzweig EB, Romer LH. Kids Mod PAH trial: A multicenter trial comparing mono- versus duo-therapy for initial treatment of pediatric pulmonary hypertension. Pulm Circ. 2023 Oct;13(4):e12305. PMCID: PMC10617301 |
56. Boeding S, Aguilera V, Smith J, Handler S, Snyder J, Kroll K. Use of the Transcultural Integrative Ethical Decision-Making Model in the Care of a Rohingya Infant With Hypoplastic Left Heart Syndrome Ethical Human Psychology and Psychiatry. 1 October 2023;25(2):135-151. |
57. Blanch-Granada A, Samyn MM, Handler SS, Gerardin JF, Goot B, Hraška V, Cava JR, LaDisa JF. Effect of Virtual Aortic Arch Reconstruction After Norwood Procedure on Cardiac Function, Energy Efficiency, and Wall Shear Stress from Multiscale Simulations Current Cardiovascular Imaging Reports. December 2023;16(12):117-127. |
58. O'Byrne ML, McHugh KE, Huang J, Song L, Griffis H, Anderson BR, Bucholz EM, Chanani NK, Elhoff JJ, Handler SS, Jacobs JP, Li JS, Lewis AB, McCrindle BW, Pinto NM, Sassalos P, Spar DS, Pasquali SK, Glatz AC. Cumulative In-Hospital Costs Associated With Single-Ventricle Palliation JACC: Advances. June 2022;1(2). |
59. Avitabile CM, Krishnan US, Yung D, Handler SS, Varghese N, Bates A, Fineman J, Sullivan R, Friere G, Austin E, Mullen MP, Pereira C, Christensen EJ, Yenokyan G, Collaco JM, Abman SH, Romer L, Dunbar Ivy D, Rosenzweig EB. Actigraphy methodology in the Kids Mod PAH trial: Physical activity as a functional endpoint in pediatric clinical trials. Pulm Circ. 2024 Jan;14(1):e12339. PMCID: PMC10923039 |
