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CURRICULUM VITAE

Suresh Kumar PhD
Associate Professor
Department of Pathology
Division of Administration

OFFICE ADDRESS:
Children's Research Institute
9000 W Wisconsin Ave
Milwaukee, WI 53226
Phone: 414-955-2448
Fax: 414-955-6533
Email: skumar@mcw.edu

EDUCATION:
1990 - Present B.Sc Loyola college, Madras, India
1992 - Present M.Sc Madurai Kamaraj University, Madurai, India
1998 - Present Ph.D Osmania University, Hyderabad, India

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
1998 - 2000 PDF, Linkoing University, Linkoping, Sweden
2000 - 2005 PDF, Medical college of Wisconsin, Milwaukee, WI
2005 - 2008 Research Scientist, Medical College of WIsconsin, Milwaukee, WI

FACULTY APPOINTMENTS:
2008 - Present Assistant Professor, Pathology, Medical College of Wisconsin, Milwaukee, WI

ADMINISTRATIVE APPOINTMENTS:
2008 - 2015 Imaging Specialist, Children's Research Institute Imaging Core, Medical College of Wisconsin, Milwaukee, WI
2015 - Present Scientific Director, Imaging Facility, Neuro Science Research Center, Milwaukee,, WI
2015 - Present Director, Children's Research Institute Imaging Core, Medical College of Wisconsin, Milwaukee,, WI

RESEARCH ADMINISTRATIVE APPOINTMENTS:
2015 - Present Director, Children's Research Institute Imaging Core, Medical College of
2015 - Present Scientific Director, Imaging Facility, Neuro Science Research Center, Milwaukee WI
Wisconsin, Milwaukee WI

AWARDS AND HONORS:
1990 - 1992 Scholarship award (Masters), Department of Biotechnology (India)
1993 - 1995 Junior Fellowship (Ph.D), Council of Scientific and Industrial Research (India)
1995 - 1998 Senior Research Fellow, Council of Scientific and Industrial Research (India)
2012 Travel Grant, American Society of Cell Biology (USA)

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
2002 - 2005 American Society of cell Biology (Member)
2018 - Present American Heart Association (Member)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
2015 - Present IJBMB
2015 - Present PLOSone

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
miRNA mediated cross talk in CRS4: The role of the miR21p/PPAR-alpha pathway
Source:
NIH
Role:
Cosultant
PI:
Dr. Kriegel A
Dates:
07/01/2016 - 04/30/2021
Direct Funds:
$1,285,000 (total for all years)
 
Title:
Role of Mitochondrial Trifunctional Protein Mutations in
Source:
CRI
Role:
Principal Investigator
Dates:
04/01/2017 - 05/30/19
Direct Funds:
$150,000 (total for all years)
 
Pending
Peer Review
Title:
Ovarian Cancer Chemoresistance Through CLPTM1L/GRP78
Source:
NIH
Role:
Co-Investigator
Dates:
07/01/2019 - 06/30/2023
Direct Funds:
$1,285,000 (total for all years)
 
Prior
Peer Review
Title:
Role of MTP alpha variant in infant's growth and survival
Source:
NIH Advancing Translational Sciences
Role:
Principal Investigator
Dates:
10/31/2016 - 05/01/2017
Direct Funds:
$12,000 (total for all years)
 

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Suresh Kumar, Another biomarker for, Department of Medicine Grand Rounds, Medical College of Wisconsin, 10/05/2005
 

COMMITTEE SERVICE:
Medical College of Wisconsin
2014 - 2018 Research Affairs Grant
2014 - 2017 Member (Adhoc) American Heart Association Grant Review Panel
2014 - 2017 Clinical & Translational Sciences Institute, Pilot grant
2014 - 2018 Cancer Center Basic Science Seed Grant
2014 - Present Member (Adhoc) of CSR-ECR Program
2016 - 2017 University of Wisconsin Milwaukee, Research Growth Initiative Grant
 

PROGRAMMATIC DEVELOPMENTS:
 
Research Programs
2007 - Present Director CRI imaging core
2016 - Present Scientific Director NRC imaging core
 
 
 

DISCOVERIES:
Identified a new isoform of Human Trifunctional protein alpha Jung-Ja P Kim, Paula E North and Suresh N Kumar (2009) NCBI : Nucleotide


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Suresh N Kumar and Guntupalli Venkateswerlu. (1997) Involvement of an endogenous metalloprotease in the activation of protoxin in Bacillus thuringiensis subsp. Kurstaki. Biochem. Mol. Biol. Internat. 42(5): 901-908.
2. Suresh N Kumar and Guntupalli Venkateswerlu. (1998) Endogenous protease activated 66 kDa toxin from Bacillus thuringiensis subsp. kurstaki active against Spodoptera littoralis. FEMS Microbiol. Lett. 159(1): 113-120.
3. Suresh N Kumar, Sreelatha T Reddy and Guntupalli Venkateswerlu. (1998) Effect of SDS on Con A-sepharose during affinity chromatography of high-affinity binding toxin protein of Bacillus thuringiensis subsp. Kurstaki. Anal. Lett. 31 (10): 1677-1687.
4. Suresh N Kumar and Guntupalli Venkateswerlu. (1998) Intracellular proteases in sporulated Bacillus thuringiensis subsp. kurstaki and their role in protoxin activation. FEMS Microbiol. Lett. 166 (2): 377-382.
5. Suresh N Kumar, Eugene A Konorev, Deepika Aggarwal and Balaraman Kalyanaraman. (2011) Analysis of proteome changes in doxorubicin treated adult rat cardiomyocyte. Journal of Proteomics 74(5): 683-697 PMID : 21338723
6. Noah P Zimmerman, Suresh N Kumar, Jerrold R Turner, Michael B Dwinell(2011) Cyclic AMP dysregulates intestinal epithelial cell restitution through PKA and the small GTPase RhoA. Inflamatory Bowel Diseases (Special accept without external review) [Epub ahead of publication] PMID : 21993975
7. Marija Renic, Suresh N Kumar, Mathew A Florence, Nashaat Z Gerges, Debebe Gebremedhin, J Russell Falck, David R Harder and Richard J Roman (2012) Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures. Am. J. Physiol. Heart & Circ. Physiol. 302(6): H1285-1293 PMID : 22245774
8. Soonyean Hwang, Noah P Zimmerman, Kimberle A Agle, Suresh N Kumar, Michele A Battle, Jerrold R Turner and Michael B Dwinell. (2012) E-cadherin is a critical effector of basal and inducible intestinal epithelial restitution. J. Biol. Chem. 287 (26): 22227-22240 PMID : 22549778.
9. Kathryn E Marshall, Amber J Tomasini, Khadijah Makky, Suresh N Kumar and Alan N Mayer (2010) Dynamic Lkb1-TORC1 signaling as a possible mechanism for regulating the endoderm intestine transition. Developmental Dynamics 239: 3000-3012 PMID: 21204094 Erratum published - (2011) Developmental Dynamics 240(2): 459
10. Hong W, Khampang P, Erbe C, Kumar S, Taylor SR, Kerschner JE. Nontypeable Haemophilus influenzae inhibits autolysis and fratricide of Streptococcus pneumoniae in vitro. Microbes Infect. (2014) 16(3):203-13. PMID: 24269704
11. Tabatabai NM, North PE, Regner KR, Kumar SN, Duris CB and Blodgett AB. De novo expression of sodium-glucose cotransporter SGLT2 in Bowman's capsule coincides with replacement of parietal epithelial cell layer with proximal tubule-like epithelium. J Membr Biol. (2014) 247(8):675-83 PubMed PMID: 24906870
12. Cossette SM, Bhute VJ, Bao X, Harmann LM, Horswill MA, Sinha I, Gastonguay A, Pooya S, Bordas M, Kumar SN, Mirza SP, Palecek SP, Strande JL, and Ramchandran R. Sucrose Nonfermenting-Related Kinase Enzyme-Mediated Rho-Associated Kinase Signaling is Responsible for Cardiac Function. Circ Cardiovasc Genet. (2016):474-486. PMID: 27780848
13. Jin Y, Hu W, Liu T, Rana U, Aguilera-Barrantes I, Kong A, Kumar SN, Wang B, Gao P, Wang X, Duan Y, Shi A, Song D, Yang M, Li S, Han B, Zhao G, Fan Z and Miao QR (2018) Nogo-B receptor increases the resistance of estrogen receptor positive breast cancer to paclitaxel. Cancer Lett. 419: 233-244
14. Cheng G, Zielonka M, Dranka B, Kumar SN, Myers CR, Bennett B, Garces AM, Dias Duarte Machado LG, Thiebaut D, Ouari O, Hardy M, Zielonka J, Kalyanaraman B. Detection of mitochondria-generated reactive oxygen species in cells using multiple probes and methods: Potentials, pitfalls, and the future. J Biol Chem. (2018) 293(26):10363-10380. PMID: 29739855
15. Jeschke JC, Mayne CG, Ziegelbauer J, DeCiantis CL, Singh S, Kumar SN, Suchi M, Iwakura Y, Drobyski WR, Salzman NH, Williams CB. A model of TH17-associated ileal hyperplasia that requires both IL-17A and IFN╬│ to generate self-tolerance and prevent colitis. Mucosal Immunol. (2018) 11(4):1127-1137. PMID: 29728642
16. Chowdhury TA, Koceja C, Eisa-Beygi S, Kleinstiver BP, Kumar SN, Lin CW, Li K, Prabhudesai S, Joung JK, Ramchandran R. Temporal and Spatial Post-Transcriptional Regulation of Zebrafish tie1 mRNA by Long Noncoding RNA During Brain Vascular Assembly. Arterioscler Thromb Vasc Biol. (2018) 38(7):1562-1575 PMID: 29724820
17. Zemanovic S, Ivanov MV, Ivanova LV, Bhatnagar A, Michalkiewicz T, Teng RJ, Kumar S, Rathore R, Pritchard KA Jr, Konduri GG, Afolayan AJ. Dynamic Phosphorylation of the C Terminus of Hsp70 Regulates the Mitochondrial Import of SOD2 and Redox Balance. Cell Rep. (201825(9):2605-2616.e7. PMID: 30485823
 

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