CURRICULUM VITAE
Susanne M. Cabrera MD
Susanne M. Cabrera MD
Associate Professor
Department of Pediatrics
Division of Endocrinology
Department of Pediatrics
Division of Endocrinology
OFFICE ADDRESS: |
Children's Corporate Center |
999 N 92 St |
Milwaukee, WI 53226 |
Phone: 414-266-6750 |
Fax: 414-266-6749 |
SPECIALTY BOARDS AND CERTIFICATION: |
Board Certified | Issue Date | Expiration |
Pediatric Endocrinology | 11/13/2013 | 12/19/2024 |
AWARDS AND HONORS: |
2021 Teaching Pin, Department of Pediatrics, Medical College of Wisconsin |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
2011 - Present American Diabetes Association (Member) |
2014 - Present American Academy of Pediatrics |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorship |
01/2019 - Present Deputy Editor, Pediatrics Review and Education Program (PREP) Endocrinology Editorial Board, American Academy of Pediatrics (3-year term) |
Editorial Board |
07/2015 - 12/2018 PREP Endocrinology Editorial Board, American Academy of Pediatrics |
01/2022 - 12/2023 Editorial Board, The Journal of Clinical Endocrinology & Metabolism |
Journal Review |
11/2013 - Present ad hoc International Journal of Pediatric Endocrinology |
05/2014 - Present ad hoc Pediatric Diabetes |
03/2020 - Present ad hoc Journal of Clinical Endocrinology and Metabolism |
03/2021 - Present current ad hoc Diabetes Care |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2012 - Present Member, Children's Research Institute, Developmental Genetics and Genomics Research Unit, Children's Hospital of Wisconsin |
2012 - Present Member, Max McGee National Research Center for Juvenile Diabetes, Medical College of Wisconsin |
2014 - Present Grant Reviewer, Children's Research Institute Intramural Pilot Grant, Children's Hospital of Wisconsin |
2014 - Present Grant Reviewer, Clinical Translational Science Institute Pilot Grant, Southwestern Wisconsin CTSI |
2017 - 2020 Invited Member, Medical Advisor Council, Type One Nation Summit, Southeastern Wisconsin JDRF |
2017 - 2020 Invited Member, Medical Advisor Council, Type One Nation Summit, Southeastern Wisconsin JDRF |
2017 - 2019 Invited Member, Board of Directors, Midwest Pediatric Endocrine Society |
2018 - Present ad hoc member, TrialNet Publications and Presentations Committee, TrialNet Consortium |
2018 Invited Reviewer, We care Fund Faculty Seed Grants, We Care Fund Scientific Review Committee, Department of Surgery, Medical College of Wisconsin |
2020 - Present Member, Southeast Wisconsin Community Leadership Board, American Diabetes Association |
2020 - Present Co-chair, Underrepresented Minority Recruitment and Retention Committee, Type 1 Diabetes TrialNet Consortium |
2021 Member, NIH Special Review Panel, Program to Advance the Career Development of Scientists from Diverse Backgrounds Conducting Nutrition, Obesity, Diabetes and Related Research |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
07/01/2015 - 06/30/2018 Member, PREP Endocrinology Board, American Academy of Pediatrics |
2018 - Present Member, TrialNet Publications and Presentations Committee |
2020 - Present Co-Chair, Underrepresented Minority Recruitment and Retention Committee, Type 1 Diabetes TrialNet Consortium |
2021 Member, NIH Special Review Panel, Program to Advance the Career Development of Scientists from Diverse Backgrounds Conducting Nutrition, Obesity, Diabetes, and Related Research, NIH |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
Regional |
Cabrera SM, Diabetes in the Teen, Best Practices Conference, Glacier Canyon Lodge, Wisconsin Dells, WI, USA, 03/08/2013 |
Cabrera SM, Clinical Trials in Type 1 Diabetes, World Diabetes Day - JDRF Southeastern Wisconsin Chapter, Blue Harbor Resort and Conference Center, Sheboygan, Wisconsin, 11/14/2015 |
Cabrera SM, Gender Identity and Gender Dysphoria, Wisconsin Academy of Physician Assistants Spring Conference, Madison, WI, 04/06/2022 |
Local |
Cabrera SM, Premature Ovarian Insufficiency, Endocrine Grand Rounds, Indiana University School of Medicine, 05/10/2010 |
Cabrera SM, The beta cell as therapeutic target in type 1 and type 2 diabetes, Endocrine Grand Rounds, Indiana University School of Medicine, 01/01/2011 |
Cabrera SM, Prediction of type 1 diabetes mellitus and prevention strategies, Department of Pediatrics Grand Rounds, Indiana University School of Medicine and Riley Hospital for Children, 07/18/2012 |
Cabrera SM, Current and novel prediction techniques of type 1 diabetes mellitus and on-going prevention strategies, RIP/Diabetes Journal Club, Medical College of Wisconsin, 10/02/2012 |
Cabrera SM, Prediction and Prevention of Type 1 Diabetes: Where we're at and where we're going, Department of Pediatrics Grand Rounds, Medical College of Wisconsin, 11/15/2012 |
Cabrera SM, Thyroid disease in the adolescent, Section of Adolescent Medicine Weekly Academic Conference, Medical College of Wisconsin, 02/15/2013 |
Cabrera SM, Perioperative Diabetes Management, Pediatric Surgery Basic Science Conference, Medical College of Wisconsin, 08/27/2013 |
Cabrera SM, 5-alpha-reductase deficiency: a case report, Disorders of Sexual Development Multidisciplinary Conference, Children's Hospital of Wisconsin, 08/29/2013 |
Cabrera, SM, Medical care of transgender children, Division of Adolescent Medicine Grand Rounds, Children's Hospital of Wisconsin, 01/12/2017 |
Cabera SM, Care of gender-non-conforming and transgender youth, Division of Psychiatry Grand Rounds, Children’s Hospital of Wisconsin, 02/15/2018 |
Cabrera SM, GI-mediated interventions to reduce T1D susceptibility, Children’s Research Institute Grand Rounds (CME), Children’s Hospital of Wisconsin, 02/23/2018 |
Cabrera SM, The CHW Gender Health Clinic: providing comprehensive care to gender non- conforming and transgender youth, Department of Pediatric Grand Rounds (CME), Children’s Hospital of Wisconsin, 08/24/2018 |
Cabrera SM, Providing specialty care to gender non-conforming and transgender youth, Division of Allergy/Immunology Grand Rounds, Children’s Hospital of Wisconsin, 09/14/2018 |
Cabrera SM, Clinical trials to alter T1D susceptibility in at-risk children, Center for Advancing Population Science, Medical College of Wisconsin, 02/18/2019 |
Cabrera SM, Gender Health Care at Children’s Hospital of Wisconsin, Social Work Noon Conference Series, Children’s Hospital of Wisconsin, 05/29/2019 |
Cabrera SM, Care of Gender Diverse Youth, CAP Didactics, Department of Pediatric Psychiatry, Medical College of Wisconsin, 04/29/2020 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
National |
Monnier (CABRERA) SM, Rapid and controlled polymerization of lactide by structurally characterized ferric alkoxides, National American Chemical Society Undergraduate Symposium, San Diego, CA, USA, 10/01/2001 - Present |
Cabrera SM, Behzadi JM, DiMeglio LA, and Walvoord EC, Five-year glycemic control in children with type 1 diabetes: does the type of initial education matter?, Endocrine Society National Meeting, San Francisco, CA, USA, 06/20/2008 - Present |
Cabrera SM, Alvarez R, Kaefer MN, Eugster EA, and Nebesio TD, Unexpected finding of intact distal vagina in an infant with mixed gonadal dysgenesis, Endocrine Society Annual Meeting, Poster Session, San Diego, CA, USA, 06/15/2010 - Present |
Cabrera SM, Tersey SA, Morris M, Nadler JL, and Mirmira RG, Combination therapy with growth-promoting and pro-differentiation agents increases beta cell mass and reduces insulitis in diabetic NOD mice., American Diabetes Association 71st Scientific Meeting, Guided Audio Tour Presentation, San Diego, CA, USA, 07/20/2011 - Present |
Cabrera SM, Eugster EA, Incidence and defining characteristics of pseudoprecocious puberty in children with severe primary hypothyroidism., Pediatric Endocrine Society Meeting, Presidential Poster Session and Poster Symposium, Boston, MA, USA, 04/01/2012 - Present |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
09/2014 - Present Director, Clinical Competency Committee, Pediatric Endocrinology Fellowship Program, Endocrinology, Pediatrics, Medical College of Wisconsin |
08/2015 - Present Member, Scholarly Oversight Committee, Pediatric Endocrinology Fellowship Program, Endocrinology, Pediatrics, Medical College of Wisconsin |
01/2021 Member, Internal Division Funding Review Committee, Endocrinology, Pediatrics, Medical College of Wisconsin |
10/2021 - Present Member, Scholarly Oversight Committee, Pediatric Hospitalist Fellow, Pediatrics |
Hospital |
09/2016 - 09/2017 Member, LEAN Committee for Improved Efficiency and Patient Care, Endocrinology, Pediatrics, Children’s Hospital of Wisconsin Diabetes and Endocrine Clinic |
07/2018 Member, Sexual Orientation and Gender Identity EPIC Committee, Endocrinology, Pediatrics, Children’s Hospital of Wisconsin |
09/2018 - 01/2019 Content Expert, Gender Identity Education Project, Endocrinology, Pediatrics, Children’s Hospital of Wisconsin |
MCW TEACHING ACTIVITIES: |
Resident and Fellow Education |
09/01/2012 - Present Ad lib mentor for pediatric residents in preparation of endocrine-based cases for Professor Rounds and Med Peds Noon Conference (approximately 2-3 times/year) |
09/2015 - 12/2016 Staff pediatric endocrinology fellows during their continuity diabetes clinics (12/year) |
EXTRAMURAL TEACHING: |
Community/Lay Public |
05/2013 - Present Medical College of Wisconsin/Children's Hospital of Wisconsin, Informational talks about type 1diabetes research opportunities at MCW/CHW (educational booths at community events including JDRF walks, community adult endocrinology groups, conferences, and diabetes summer camps (4/year)) |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Fisher MM, Cabrera SM, Imel EA. Successful treatment of neonatal severe hyperparathyroidism with cinacalcet in two patients. Endocrinol Diabetes Metab Case Rep. 2015;2015:150040. PMCID: PMC4496565 |
2. Chen YG, Cabrera SM, Jia S, Kaldunski ML, Kramer J, Cheong S, Geoffrey R, Roethle MF, Woodliff JE, Greenbaum CJ, Wang X, Hessner MJ. Molecular signatures differentiate immune states in type 1 diabetic families. Diabetes. 2014 Nov;63(11):3960-73. PMCID: PMC4207392 |
3. Cabrera SM, Bright GM, Frane JW, Blethen SL, Lee PA. Age of thelarche and menarche in contemporary US females: a cross-sectional analysis. J Pediatr Endocrinol Metab. 2014 Jan;27(1-2):47-51. PMCID: PMC4137967 |
4. Cabrera SM, Colvin SC, Tersey SA, Maier B, Nadler JL, Mirmira RG. Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes. Clin Exp Immunol. 2013 Jun;172(3):375-82. PMCID: PMC3646436 |
5. Cabrera SM, Rogol AD. Testosterone exposure in childhood: discerning pathology from physiology. Expert Opin Drug Saf. 2013 May;12(3):375-88. |
6. Cabrera SM, Srivastava NT, Behzadi JM, Pottorff TM, Dimeglio LA, Walvoord EC. Long-term glycemic control as a result of initial education for children with new onset type 1 diabetes: does the setting matter? Diabetes Educ. 2013;39(2):187-94. PMCID: PMC4780749 |
7. Cabrera SM, DiMeglio LA, Eugster EA. Incidence and characteristics of pseudoprecocious puberty because of severe primary hypothyroidism. J Pediatr. 2013 Mar;162(3):637-9. PMCID: PMC4070005 |
8. Cabrera SM, Srivastava NT, Behzadi JM, Pottorff TM, Dimeglio LA, Walvoord EC. Long-term glycemic control as a result of initial education for children with new onset type 1 diabetes: does the setting matter? Diabetes Educ. 2013;39(2):187-94. PMCID: PMC4780749 |
9. Tersey SA, Nishiki Y, Templin AT, Cabrera SM, Stull ND, Colvin SC, Evans-Molina C, Rickus JL, Maier B, Mirmira RG. Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model. Diabetes. 2012 Apr;61(4):818-27. PMCID: PMC3314371 |
10. Cabrera SM, Alvarez R, Kaefer MN, Eugster EA, Nebesio TD. Unexpected finding of an intact distal vagina in an infant with mixed gonadal dysgenesis. J Pediatr Endocrinol Metab. 2011;24(9-10):831-3. PMCID: PMC4094021 |
11. Shull J, Monnier (CABRERA) SM, Solomon SS, Buss N, and Gerling IC. Proteome of H-411E (Liver) cells exposed to insulin and TNF-alpha: Analysis of proteins involved in insulin resistance. J Lab Clin Med 2005;145(5):275-83. |
12. Solomon SS, Buss N, Shull J, Monnier S, Majumdar G, Wu J, Gerling IC. Proteome of H-411E (liver) cells exposed to insulin and tumor necrosis factor-alpha: analysis of proteins involved in insulin resistance. J Lab Clin Med. 2005 May;145(5):275-83. |
13. Baruah H, Rector CL, Monnier SM, Bierbach U. Mechanism of action of non-cisplatin type DNA-targeted platinum anticancer agents: DNA interactions of novel acridinylthioureas and their platinum conjugates. Biochem Pharmacol. 2002 Jul 15;64(2):191-200. |
14. Baruah H, Rector CL, Monnier(CABRERA) SM, Bierbach U. Mechanism of action of non-cisplatin type DNA-targeted platinum anticancer agents: DNA interactions of novel acridinylthioureas and their platinum conjugates. Biochem Pharmacol. 2001;64(2): 191-200. |
15. O'Keefe B, Monnier (CABRERA) SM, Hillmyer M, Tolman WB. Rapid and Controlled Polymerization of Lactide by Structurally Characterized Ferric Alkoxides. J Am Chem Soc 2001;123: 339-40. |
16. O'Keefe BJ, Monnier SM, Hillmyer MA, Tolman WB. Rapid and controlled polymerization of lactide by structurally characterized ferric alkoxides. J Am Chem Soc. 2001 Jan 17;123(2):339-40. |
17. Cabrera SM, Wang X, Chen YG, Jia S, Kaldunski ML, Greenbaum CJ, Type 1 Diabetes TrialNet Canakinumab Study Group, Mandrup-Poulsen T, AIDA Study Group, Hessner MJ. Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset. Eur J Immunol. 2016 Apr;46(4):1030-46. PMCID: PMC4828314 |
18. Cabrera SM, Chen YG, Hagopian WA, Hessner MJ. Blood-based signatures in type 1 diabetes. Diabetologia. 2016 Mar;59(3):414-25. PMCID: PMC4744128 |
19. Henschel AM, Cabrera SM, Kaldunski ML, Jia S, Geoffrey R, Roethle MF, Lam V, Chen YG, Wang X, Salzman NH, Hessner MJ. Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibility. PLoS One. 2018;13(1):e0190351. PMCID: PMC5749787 |
20. Fawley J, Koehler S, Cabrera S, Lam V, Fredrich K, Hessner M, Salzman N, Gourlay D. Intestinal alkaline phosphatase deficiency leads to dysbiosis and bacterial translocation in the newborn intestine. J Surg Res. 2017 Oct;218:35-42. |
21. Narala B, Cabrera SM. Short stature The 5-Minute Pediatric Consult, 8th Edition. 1 January 2018:844-845. |
22. Hessner MJ, Cabrera SM. Broadening Our Understanding Type 1 Diabetes Heterogeneity by Exploring Effects of Race/Ethnicity on Disease Trajectory. J Clin Endocrinol Metab. 2020 Dec 01;105(12):e4961-3. PMCID: PMC7531905 |
23. Walch AM, Cobb CE, Tsaih SW, Cabrera SM. The medical transition of young adults with type 1 diabetes (T1D): a retrospective chart review identifies areas in need of improvement. Int J Pediatr Endocrinol. 2020;2020:10. PMCID: PMC7254679 |
24. Wolfgram PM, Cabrera SM. Youth Along the T2D Risk Continuum Remain Concerningly Refractory to Therapeutic Interventions. J Clin Endocrinol Metab. 2021 Jun 16;106(7):e2803-e2805. PMCID: PMC8208664 |
25. Cabrera SM, Engle S, Kaldunski M, Jia S, Geoffrey R, Simpson P, Szabo A, Speake C, Greenbaum CJ, Type 1 Diabetes TrialNet CTLA-4 Ig (Abatacept) Study Group, Chen YG, and Hessner MJ. Innate immune activity as a predictor of persistent insulin secretion and association with responsiveness to CTLA4-Ig treatment in recent onset type 1 diabetes. Diabetologia.2018;61(11):2356-2370. |
26. Cabrera SM, Engle S, Kaldunski M, Jia S, Geoffrey R, Simpson P, Szabo A, Speake C, Greenbaum CJ, Type 1 Diabetes TrialNet CTLA4-Ig (Abatacept) Study Group, Chen YG, Hessner MJ. Innate immune activity as a predictor of persistent insulin secretion and association with responsiveness to CTLA4-Ig treatment in recent-onset type 1 diabetes. Diabetologia. 2018 Nov;61(11):2356-2370. PMCID: PMC6182660 |
27. Fanning B, Narala B, Cabrera SM. Obtundation and respiratory depression during diabetic ketoacidosis. Pediatr Rev. Accepted for publication |
28. Cabrera SM., Coren AT, Pant T, Ciecko AE, Jia S, Roethle MF, Simpson PM, Atkinson SN, Salzman NH, Chen YG, Hessner MJ. 2022. Probiotic normalization of systemic inflammation in siblings of Type 1 diabetes patients: An open-label pilot study. Scientific Reports. 12(1):3306. doi: 10.1038/s41598-022-07203-6. PMID: 35228584. |
29. Sargin P, Roethle MF, Jia S, Pant T, Ciecko AE, Atkinson SN, Salzman NH, Teng RJ, Chen YG, Cabrera SM, Hessner MJ. <i>Lactiplantibacillus plantarum</i> 299v supplementation modulates β-cell ER stress and antioxidative defense pathways and prevents type 1 diabetes in gluten-free BioBreeding rats. Gut Microbes. 2022;14(1):2136467. PMCID: PMC9586621 |
30. Cabrera SM, Coren AT, Pant T, Ciecko AE, Jia S, Roethle MF, Simpson PM, Atkinson SN, Salzman NH, Chen YG, Hessner MJ. Probiotic normalization of systemic inflammation in siblings of type 1 diabetes patients: an open-label pilot study. Sci Rep. 2022 Feb 28;12(1):3306. PMCID: PMC8885673 |
31. Fanning BC, Narala B, Cabrera SM. Obtundation and Respiratory Depression during Diabetic Ketoacidosis. Pediatr Rev. 2023 Jun 01;44(6):340-342. |
32. Sims EK, Kulkarni A, Hull A, Woerner SE, Cabrera S, Mastrandrea LD, Hammoud B, Sarkar S, Nakayasu ES, Mastracci TL, Perkins SM, Ouyang F, Webb-Robertson BJ, Enriquez JR, Tersey SA, Evans-Molina C, Long SA, Blanchfield L, Gerner EW, Mirmira RG, DiMeglio LA. Inhibition of polyamine biosynthesis preserves β cell function in type 1 diabetes. Cell Rep Med. 2023 Nov 21;4(11):101261. PMCID: PMC10694631 |
Books, Chapters, and Reviews |
1. Cabrera SM, Henschel AM, Hessner MJ. Innate inflammation in type 1 diabetes. Transl Res. 2016 Jan;167(1):214-27. PMCID: PMC4626442 |
2. Kashmiri, HK, and SM Cabrera. 'Short Stature'. The 5 Minute Pediatric Consult Standard. Ed. Michael Cabana. 7th ed. New York: Wolters-Kluwer, 2015. |
3. Cabrera SM, Rigby MR, Mirmira RG. Targeting regulatory T cells in the treatment of type 1 diabetes mellitus. Curr Mol Med. 2012 Dec;12(10):1261-72. PMCID: PMC3709459 |
4. Cabrera SM, Henschel AM, and Hessner MJ. Innate inflammation in type 1 diabetes. Trans Res. 2015 Apr 29. Epub ahead of print. |
5. Cabrera SM, Rogol AD Testosterone exposure in childhood: discerning pathology from physiology. Expert Opin Drug Saf. 2013 May;12(3):375-88 |
6. Cabrera SM, Chen YG, Hagopian WA, Hessner MJ Blood-based signatures in type 1 diabetes. Diabetologia. 2016 Mar;59(3):414-25 |
7. Narala B, Cabrera SM. ‘Short Stature’. The 5 Minute Pediatric Consult Standard. Ed. Michael Cabana. 8th ed. New York: Wolters-Kluwer, 2018. |
8. Hessner MJ, Cabrera SM. Broadening our understanding of type 1 diabetes heterogeneity by exploring effects of race/ethnicity on disease trajectory. J Clin Endocrinol Metab. 2020 Dec 1:105(12):e4961-3. PMID 32542394. (invited commentary) |
9. Wolfgram PM, Cabrera SM. Youth along the T2D risk continuum remain concerningly refractory to therapeutic interventions. J Clin Endocrinol Metab. 2021 Jun 16;106(7):e2803-e2805. (invited commentary) |
10. Cabrera SM. Medfyle Endocrine Society, Expert Invited Commentary and Podcast in response to “Fat mass accretion from birth to 5 years and metabolic homeostasis in childhood: The Healthy Start Study (Sauder)” in JCEM May 2021 |
11. Cabrera SM. Medfyle American Diabetes Association, Expert Invited Commentary, Podcast, and Clinical Case Presentation in response to “Uncovering pathways to personalized therapies in type 1 diabetes (Linsley)” in Diabetes April 2021. |
12. Cabrera SM. “'Short Stature'. The 5 Minute Pediatric Consult Standard. Ed. Michael Cabana. 9th ed. New York: Wolters-Kluwer, 2022. |