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Arsenio Andrew Pacheco

Arsenio Andrew Pacheco profile photo picture

Institution: University of Wisconsin - Milwaukee
Department: Chemistry and Biochemistry


Publications (19)

  • Trapping of a Putative Intermediate in the Cytochrome c Nitrite Reductase (ccNiR)-Catalyzed Reduction of Nitrite: Implications for the ccNiR Reaction Mechanism. (Ali M, Stein N, Mao Y, Shahid S, Schmidt M, Bennett B, Pacheco AA) J Am Chem Soc 2019 Aug 28;141(34):13358-13371 PMID: 31381304 SCOPUS ID: 2-s2.0-85071714374 08/06/2019       10 Citations
  • Upon further analysis, neither cytochrome c554 from Nitrosomonas europaea nor its F156A variant display NO reductase activity, though both proteins bind nitric oxide reversibly. (McGarry JM, Pacheco AA) J Biol Inorg Chem 2018 Aug;23(6):861-878 PMID: 29946979 SCOPUS ID: 2-s2.0-85049113759 06/28/2018       4 Citations
  • Direct Monitoring of the Reaction between Photochemically Generated Nitric Oxide and Mycobacterium tuberculosis Truncated Hemoglobin N Wild Type and Variant Forms: An Assessment of Computational Mechanistic Predictions. (Koebke KJ, Waletzko MT, Pacheco AA) Biochemistry 2016 Feb 02;55(4):686-96 PMID: 26757411 SCOPUS ID: 2-s2.0-84957038859 01/13/2016       8 Citations
  • Correlations between the Electronic Properties of Shewanella oneidensis Cytochrome c Nitrite Reductase (ccNiR) and Its Structure: Effects of Heme Oxidation State and Active Site Ligation. (Stein N, Love D, Judd ET, Elliott SJ, Bennett B, Pacheco AA) Biochemistry 2015 Jun 23;54(24):3749-58 PMID: 26042961 PMCID: PMC4743497 SCOPUS ID: 2-s2.0-84935012019 06/05/2015       7 Citations
  • Hydrogen bonding networks tune proton-coupled redox steps during the enzymatic six-electron conversion of nitrite to ammonia. (Judd ET, Stein N, Pacheco AA, Elliott SJ) Biochemistry 2014 Sep 09;53(35):5638-46 PMID: 25137350 PMCID: PMC4159211 SCOPUS ID: 2-s2.0-84907558076 08/20/2014       17 Citations
  • Shewanella oneidensis cytochrome c nitrite reductase (ccNiR) does not disproportionate hydroxylamine to ammonia and nitrite, despite a strongly favorable driving force. (Youngblut M, Pauly DJ, Stein N, Walters D, Conrad JA, Moran GR, Bennett B, Pacheco AA) Biochemistry 2014 Apr 08;53(13):2136-44 PMID: 24645742 PMCID: PMC5047060 SCOPUS ID: 2-s2.0-84898037971 03/22/2014       9 Citations
  • Does the oxidation of nitric oxide by oxyMyoglobin share an intermediate with the metMyoglobin-catalyzed isomerization of peroxynitrite? (Koebke KJ, Pauly DJ, Lerner L, Liu X, Pacheco AA) Inorg Chem 2013 Jul 01;52(13):7623-32 PMID: 23768169 SCOPUS ID: 2-s2.0-84879756872 06/19/2013       20 Citations
  • Direct electrochemistry of Shewanella oneidensis cytochrome c nitrite reductase: evidence of interactions across the dimeric interface. (Judd ET, Youngblut M, Pacheco AA, Elliott SJ) Biochemistry 2012 Dec 21;51(51):10175-85 PMID: 23210513 PMCID: PMC3566639 SCOPUS ID: 2-s2.0-84871535247 12/06/2012       16 Citations
  • Laue crystal structure of Shewanella oneidensis cytochrome c nitrite reductase from a high-yield expression system. (Youngblut M, Judd ET, Srajer V, Sayyed B, Goelzer T, Elliott SJ, Schmidt M, Pacheco AA) J Biol Inorg Chem 2012 Apr;17(4):647-62 PMID: 22382353 PMCID: PMC3412176 SCOPUS ID: 2-s2.0-84862571732 03/03/2012       44 Citations
  • Interaction of nitric oxide with catalase: structural and kinetic analysis. (Purwar N, McGarry JM, Kostera J, Pacheco AA, Schmidt M) Biochemistry 2011 May 31;50(21):4491-503 PMID: 21524057 PMCID: PMC3140772 SCOPUS ID: 2-s2.0-79958167107 04/29/2011       63 Citations
  • Techniques for investigating hydroxylamine disproportionation by hydroxylamine oxidoreductases. (Pacheco AA, McGarry J, Kostera J, Corona A) Methods Enzymol 2011;486:447-63 PMID: 21185448 SCOPUS ID: 2-s2.0-77957255187 12/28/2010       21 Citations
  • Enzymatic interconversion of ammonia and nitrite: the right tool for the job. (Kostera J, McGarry J, Pacheco AA) Biochemistry 2010 Oct 05;49(39):8546-53 PMID: 20812758 SCOPUS ID: 2-s2.0-77957277232 09/04/2010       33 Citations
  • The effect of detergents and lipids on the properties of the outer-membrane protein OmcA from Shewanella oneidensis. (Bodemer GJ, Antholine WA, Basova LV, Saffarini D, Pacheco AA) J Biol Inorg Chem 2010 Jun;15(5):749-58 PMID: 20229092 SCOPUS ID: 2-s2.0-77953285756 03/17/2010       13 Citations
  • Kinetic and product distribution analysis of NO* reductase activity in Nitrosomonas europaea hydroxylamine oxidoreductase. (Kostera J, Youngblut MD, Slosarczyk JM, Pacheco AA) J Biol Inorg Chem 2008 Sep;13(7):1073-83 PMID: 18553112 SCOPUS ID: 2-s2.0-51849098544 06/17/2008       43 Citations
  • Cardiolipin switch in mitochondria: shutting off the reduction of cytochrome c and turning on the peroxidase activity. (Basova LV, Kurnikov IV, Wang L, Ritov VB, Belikova NA, Vlasova II, Pacheco AA, Winnica DE, Peterson J, Bayir H, Waldeck DH, Kagan VE) Biochemistry 2007 Mar 20;46(11):3423-34 PMID: 17319652 PMCID: PMC3356783 SCOPUS ID: 2-s2.0-33947386195 02/27/2007       178 Citations
  • Quantifying the photoinduced release of nitric oxide from N,N'-bis(carboxymethyl)-N,N'-dinitroso-1,4-phenylenediamine. Effect of reducing agents on the mechanism of the photoinduced reactions. (Cabail MZ, Moua V, Bae E, Meyer A, Pacheco AA) J Phys Chem A 2007 Feb 22;111(7):1207-13 PMID: 17266287 SCOPUS ID: 2-s2.0-33847717892 02/03/2007       9 Citations
  • Redox equilibria in hydroxylamine oxidoreductase. Electrostatic control of electron redistribution in multielectron oxidative processes. (Kurnikov IV, Ratner MA, Pacheco AA) Biochemistry 2005 Feb 15;44(6):1856-63 PMID: 15697211 SCOPUS ID: 2-s2.0-13644249873 02/09/2005       34 Citations
  • Laser photoinitiated nitrosylation of 3-electron reduced Nm europaea hydroxylamine oxidoreductase: kinetic and thermodynamic properties of the nitrosylated enzyme. (Cabail MZ, Kostera J, Pacheco AA) Inorg Chem 2005 Jan 24;44(2):225-31 PMID: 15651867 SCOPUS ID: 2-s2.0-12344328191 01/18/2005       14 Citations
  • Selective one-electron reduction of Nitrosomonas europaea hydroxylamine oxidoreductase with nitric oxide. (Cabail MZ, Pacheco AA) Inorg Chem 2003 Jan 27;42(2):270-2 PMID: 12693206 SCOPUS ID: 2-s2.0-0037467739 04/16/2003       27 Citations
  • Last update: 12/11/2019