Medical College of Wisconsin
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Ayan K. Ghosh PhD

Research Scientist I

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Infectious Disease

Publications (24)

  • Harnessing the Noncanonical Keap1-Nrf2 Pathway for Human Cytomegalovirus Control. (Ghosh AK, Su YP, Forman M, Keyes RF, Smith BC, Hu X, Ferrer M, Arav-Boger R) J Virol 2023 Apr 27;97(4):e0016023 PMID: 36939350 PMCID: PMC10134830 SCOPUS ID: 2-s2.0-85159161803 03/21/2023       1 Citation
  • Inhibition of Human Coronaviruses by Piperidine-4-Carboxamides (Xin Guo1, Ayan Kumar Ghosh1, Halli Miller1, Konstance Knox2, Madhuchhanda Kundu2, Francis Peterson3, David J Meyers4, Ravit Arav-Boger1*) Infectious Diseases Diagnosis & Treatment Guo X, Ghosh AK, Miller H, Knox K, Kundu M, et al. (2022) Inhibition of Human Coronaviruses by Piperidine-4-Carboxamides. Infect Dis Diag Treat 6: 199. DOI: https://doi.org/10.29011/2577-1515.100199 09/26/2022    
  • Correction for Abhishek et al., "Phosphorylation of Translation Initiation Factor 2-Alpha in Leishmania donovani under Stress Is Necessary for Parasite Survival". (Abhishek K, Sardar AH, Das S, Kumar A, Ghosh AK, Singh R, Saini S, Mandal A, Verma S, Kumar A, Purkait B, Dikhit MR, Das P) Mol Cell Biol 2022 Aug 18;42(8):e0022722 PMID: 35861535 PMCID: PMC9387245 SCOPUS ID: 2-s2.0-85136911094 07/22/2022    
  • Correction for Kumar et al., "Ascorbate Peroxidase, a Key Molecule Regulating Amphotericin B Resistance in Clinical Isolates of Leishmania donovani". (Kumar A, Das S, Purkait B, Sardar AH, Ghosh AK, Dikhit MR, Abhishek K, Das P) Antimicrob Agents Chemother 2022 Aug 16;66(8):e0082922 PMID: 35861540 PMCID: PMC9380566 SCOPUS ID: 2-s2.0-85136176094 07/22/2022    
  • The Synthesis and Anti-Cytomegalovirus Activity of Piperidine-4-Carboxamides. (Guo X, Ghosh AK, Keyes RF, Peterson F, Forman M, Meyers DJ, Arav-Boger R) Viruses 2022 Jan 25;14(2) PMID: 35215828 PMCID: PMC8876412 SCOPUS ID: 2-s2.0-85123542102 02/27/2022       1 Citation
  • Inhibition of Human Coronaviruses by Antimalarial Peroxides. (Ghosh AK, Miller H, Knox K, Kundu M, Henrickson KJ, Arav-Boger R) ACS Infect Dis 2021 Jul 09;7(7):1985-1995 PMID: 33783182 SCOPUS ID: 2-s2.0-85105043981 03/31/2021       21 Citations
  • Artemisinins target the intermediate filament protein vimentin for human cytomegalovirus inhibition. (Roy S, Kapoor A, Zhu F, Mukhopadhyay R, Ghosh AK, Lee H, Mazzone J, Posner GH, Arav-Boger R) J Biol Chem 2020 Oct 30;295(44):15013-15028 PMID: 32855235 PMCID: PMC7606667 SCOPUS ID: 2-s2.0-85094983683 08/29/2020       14 Citations
  • Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus. (Kapoor A, Ghosh AK, Forman M, Hu X, Ye W, Southall N, Marugan J, Keyes RF, Smith BC, Meyers DJ, Ferrer M, Arav-Boger R) J Med Chem 2020 Apr 23;63(8):3896-3907 PMID: 32191456 PMCID: PMC7386824 SCOPUS ID: 2-s2.0-85084027851 03/20/2020       8 Citations
  • Development of a sandwich ELISA to detect Leishmania 40S ribosomal protein S12 antigen from blood samples of visceral leishmaniasis patients. (Zhang WW, Ghosh AK, Mohamath R, Whittle J, Picone A, Lypaczewski P, Ndao M, Howard RF, Das P, Reed SG, Matlashewski G) BMC Infect Dis 2018 Oct 03;18(1):500 PMID: 30285653 PMCID: PMC6171325 SCOPUS ID: 2-s2.0-85054383273 10/05/2018       14 Citations
  • Leishmania donovani Inhibitor of Serine Peptidases 2 Mediated Inhibition of Lectin Pathway and Upregulation of C5aR Signaling Promote Parasite Survival inside Host. (Verma S, Mandal A, Ansari MY, Kumar A, Abhishek K, Ghosh AK, Kumar A, Kumar V, Das S, Das P) Front Immunol 2018;9:63 PMID: 29434593 PMCID: PMC5796892 SCOPUS ID: 2-s2.0-85041104497 02/13/2018       20 Citations
  • Reduced pathogenicity of fructose-1,6-bisphosphatase deficient Leishmania donovani and its use as an attenuated strain to induce protective immunogenicity. (Saini S, Ghosh AK, Das S, Singh R, Abhishek K, Verma S, Kumar A, Mandal A, Purkait B, Sinha KK, Das P) Vaccine 2018 Feb 21;36(9):1190-1202 PMID: 29395522 SCOPUS ID: 2-s2.0-85041122722 02/06/2018       3 Citations
  • l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis. (Mandal A, Das S, Kumar A, Roy S, Verma S, Ghosh AK, Singh R, Abhishek K, Saini S, Sardar AH, Purkait B, Kumar A, Mandal C, Das P) Front Immunol 2017;8:839 PMID: 28798743 PMCID: PMC5526900 SCOPUS ID: 2-s2.0-85026520998 08/12/2017       28 Citations
  • Deciphering the interplay between cysteine synthase and thiol cascade proteins in modulating Amphotericin B resistance and survival of Leishmania donovani under oxidative stress. (Singh K, Ali V, Pratap Singh K, Gupta P, Suman SS, Ghosh AK, Bimal S, Pandey K, Das P) Redox Biol 2017 Aug;12:350-366 PMID: 28288415 PMCID: PMC5349463 SCOPUS ID: 2-s2.0-85014844342 03/14/2017       36 Citations
  • Glucose-6-phosphate dehydrogenase and Trypanothione reductase interaction protects Leishmania donovani from metalloid mediated oxidative stress. (Ghosh AK, Saini S, Das S, Mandal A, Sardar AH, Ansari MY, Abhishek K, Kumar A, Singh R, Verma S, Equbal A, Ali V, Das P) Free Radic Biol Med 2017 May;106:10-23 PMID: 28179112 SCOPUS ID: 2-s2.0-85012113427 02/10/2017       19 Citations
  • Phosphorylation of Translation Initiation Factor 2-Alpha in Leishmania donovani under Stress Is Necessary for Parasite Survival. (Abhishek K, Sardar AH, Das S, Kumar A, Ghosh AK, Singh R, Saini S, Mandal A, Verma S, Kumar A, Purkait B, Dikhit MR, Das P) Mol Cell Biol 2017 Jan 01;37(1) PMID: 27736773 PMCID: PMC5192082 SCOPUS ID: 2-s2.0-85008155985 11/01/2016       14 Citations
  • Deprivation of L-Arginine Induces Oxidative Stress Mediated Apoptosis in Leishmania donovani Promastigotes: Contribution of the Polyamine Pathway. (Mandal A, Das S, Roy S, Ghosh AK, Sardar AH, Verma S, Saini S, Singh R, Abhishek K, Kumar A, Mandal C, Das P) PLoS Negl Trop Dis 2016 Jan;10(1):e0004373 PMID: 26808657 PMCID: PMC4726550 SCOPUS ID: 2-s2.0-84969420632 01/26/2016       37 Citations
  • Development of a Simple Dipstick Assay for Operational Monitoring of DDT. (Ismail HM, Kumar V, Singh RP, Williams C, Shivam P, Ghosh A, Deb R, Foster GM, Hemingway J, Coleman M, Coleman M, Das P, Paine MJ) PLoS Negl Trop Dis 2016 Jan;10(1):e0004324 PMID: 26760773 PMCID: PMC4711890 SCOPUS ID: 2-s2.0-84961349997 01/14/2016       11 Citations
  • DDT-based indoor residual spraying suboptimal for visceral leishmaniasis elimination in India. (Coleman M, Foster GM, Deb R, Pratap Singh R, Ismail HM, Shivam P, Ghosh AK, Dunkley S, Kumar V, Coleman M, Hemingway J, Paine MJ, Das P) Proc Natl Acad Sci U S A 2015 Jul 14;112(28):8573-8 PMID: 26124110 PMCID: PMC4507214 SCOPUS ID: 2-s2.0-84937232322 07/01/2015       73 Citations
  • Metabolic reconfiguration of the central glucose metabolism: a crucial strategy of Leishmania donovani for its survival during oxidative stress. (Ghosh AK, Sardar AH, Mandal A, Saini S, Abhishek K, Kumar A, Purkait B, Singh R, Das S, Mukhopadhyay R, Roy S, Das P) FASEB J 2015 May;29(5):2081-98 PMID: 25690656 SCOPUS ID: 2-s2.0-84932617791 02/19/2015       38 Citations
  • Up-regulation of silent information regulator 2 (Sir2) is associated with amphotericin B resistance in clinical isolates of Leishmania donovani. (Purkait B, Singh R, Wasnik K, Das S, Kumar A, Paine M, Dikhit M, Singh D, Sardar AH, Ghosh AK, Das P) J Antimicrob Chemother 2015 May;70(5):1343-56 PMID: 25667407 SCOPUS ID: 2-s2.0-84929751492 02/11/2015       22 Citations
  • Unmethylated CpG motifs in the L. donovani DNA regulate TLR9-dependent delay of programmed cell death in macrophages. (Das S, Ghosh AK, Singh S, Saha B, Ganguly A, Das P) J Leukoc Biol 2015 Feb;97(2):363-78 PMID: 25473100 SCOPUS ID: 2-s2.0-84925372254 12/05/2014       15 Citations
  • Ascorbate peroxidase, a key molecule regulating amphotericin B resistance in clinical isolates of Leishmania donovani. (Kumar A, Das S, Purkait B, Sardar AH, Ghosh AK, Dikhit MR, Abhishek K, Das P) Antimicrob Agents Chemother 2014 Oct;58(10):6172-84 PMID: 25114128 PMCID: PMC4187981 SCOPUS ID: 2-s2.0-84907279801 08/13/2014       33 Citations
  • Spinigerin induces apoptotic like cell death in a caspase independent manner in Leishmania donovani. (Sardar AH, Das S, Agnihorti S, Kumar M, Ghosh AK, Abhishek K, Kumar A, Purkait B, Ansari MY, Das P) Exp Parasitol 2013 Dec;135(4):715-25 PMID: 24184774 SCOPUS ID: 2-s2.0-84887689546 11/05/2013       24 Citations
  • Diagnosis of visceral leishmaniasis in Bihar India: comparison of the rK39 rapid diagnostic test on whole blood versus serum. (Matlashewski G, Das VN, Pandey K, Singh D, Das S, Ghosh AK, Pandey RN, Das P) PLoS Negl Trop Dis 2013;7(5):e2233 PMID: 23717700 PMCID: PMC3662694 SCOPUS ID: 2-s2.0-84878511483 05/30/2013       26 Citations
    • Last update: 11/30/2023